LOCUS       NZ_KZ195572            21056 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. CS057 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195572
VERSION     NZ_KZ195572.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS057
  ORGANISM  Streptomyces sp. CS057
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 265.32x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188345.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 02:40:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,152
            CDSs (total)                      :: 7,074
            Genes (coding)                    :: 6,991
            CDSs (with protein)               :: 6,991
            Genes (RNA)                       :: 78
            rRNAs                             :: 10, 6 (16S, 23S)
            complete rRNAs                    :: 10, 6 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 23 of 83
            Pseudo Genes (incomplete)         :: 71 of 83
            Pseudo Genes (internal stop)      :: 4 of 83
            Pseudo Genes (multiple problems)  :: 14 of 83
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:25:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8309141
            Orig. end                         :: 8330197
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195572.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..21056
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="37"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11056](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(970..1896)
                     /locus_tag="B9W61_RS35560"
                     /old_locus_tag="B9W61_35530"
     CDS             complement(970..1896)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459150.1"
                     /locus_tag="B9W61_RS35560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35530"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_087767651.1"
                     /transl_table=11
                     /translation="MDIEAVRTFVTVADTGQFQEAAVELRVSQQAVSKRVAGLERVLGV
                     TLFVRTARGAHPTADGQAFLPHAREVLRAVERAAASVRPGDRVLRVDVLHRRIAPALAV
                     RGFYQAHPGTDLDVVTLADRNVTGAAEAVRAGEIDATFRAVPVGALPDGISAERVLDDP
                     LQLLVGPRHPLASARSLAPADLAGHRIWIPGIKQGTEWAAYYDRLAEDFGLRIDAVGPD
                     FGTEALMDSIADSAALATLVGSRDRYVWPAAHDLRRIPVVGPTPVYPHVFLYRTGNPHP
                     VLAALRRYLVRARPESPADAWTPGWAR"
     gene            2005..2619
                     /locus_tag="B9W61_RS35565"
                     /old_locus_tag="B9W61_35535"
     CDS             2005..2619
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971247.1"
                     /locus_tag="B9W61_RS35565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35535"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_087768114.1"
                     /transl_table=11
                     /translation="MTQEDGELDSLVRKRIRALRVAQGWSLEELAGRAKVSQSTLSRIE
                     NGRRRLALDQLVTLARALDTSLDQLVETASDDVVSNPTIDGAHGQMRWPIKAEPGLTVI
                     RQRLTEPPPDNPSRLRAHPGREWLVVLSGTAILLLGNRRLRIETNQAAEFPTMLPHAIG
                     AEGGPCELLGIFDRDARRGHQRGEGAEQANRPTPPPGRSLP"
     gene            complement(2773..3909)
                     /locus_tag="B9W61_RS35570"
                     /old_locus_tag="B9W61_35540"
     CDS             complement(2773..3909)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893396.1"
                     /locus_tag="B9W61_RS35570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35540"
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_087767652.1"
                     /transl_table=11
                     /translation="MKFRTRSSAIIGTLCLVTSLALASASAVEPADPVKPVSASLTEVA
                     RAQGPSAGAAGPDDTLWIAERAGTVRVLDDQGLGAPVLDISDETTTDGERGLLGVAFDK
                     TFAHFYISYTDLEGTSTIDEFAVEGGQLQPETRRTVLTQTQPYANHNGGDIKFGPDGYL
                     YIAFGDGGSGGDPHGNGQKLDTLLGKLLRIDPTGGEPYAVPADNPFVDDANAKDEIWAY
                     GLRNPWRFSFDAGTGDLLIGDVGQSDWEEIDWAPADSEGGENYGWASMEGTHPFRGGTE
                     PANHVPPVYEYDRTGLGCSVTGGFVYRGDALPDLRGSYVFSDYCDGTLRTLRMTDGEVT
                     GVGDLGVSGGEVISFAEGGDGELYVLGSNGVISRVDPA"
     misc_feature    complement(4052..4067)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.0"
                     /tool="antismash"
     misc_feature    complement(4181..4195)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.66"
                     /tool="antismash"
     misc_feature    4182..4196
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.19"
                     /tool="antismash"
     misc_feature    complement(4268..4282)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.15"
                     /tool="antismash"
     misc_feature    4269..4283
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     gene            4389..6518
                     /locus_tag="B9W61_RS35575"
                     /old_locus_tag="B9W61_35545"
     CDS             4389..6518
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971249.1"
                     /locus_tag="B9W61_RS35575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35545"
                     /product="glycoside hydrolase family 6 protein"
                     /protein_id="WP_087767653.1"
                     /transl_table=11
                     /translation="MRSRGATPHAPHAFRRRAAAALSALIMGAALAVAVPGQASAAARV
                     DNPYAGATAYVNPDWSARAAAEPGGEVIADEPSFVWMDRIAAIGGTPGARGLRAHLDTA
                     VSQGADLFQVVIYNLPGRDCAALASNGELGPTELGRYKDDYIDPIADILGDPAYASLRI
                     VTLIEPDSLPNLVTNAGGTPGSTPECATMKANGNYEKGIGYALHTLGALPNVYNYVDAA
                     HHGWLGWDSNFVPAAQQFKKAATTEGATVSDVHGFIVNTANYSALKEPHFAVTDSVNGT
                     TVRQSRWVDWNYYVDELSFAKALRTELVRQGFASDIGMLIDTARNGWGGSDRPAGPGPL
                     TSTDAYVDGSRTDRRIHAGNWCNQSGAGIGERPTAAPEPGIDAYVWAKPPGESDGSSEP
                     IDNDEGKGFDRMCDPTYTGNGRNGFNLTGALPDSPVAGHWFSGQFQELLRNAHPPLDGG
                     SGGEEDTQAPTVPTNLRVTAKSSSSVTLAWTASTDDTGVTGYDILRDGAPVGTTTATTY
                     TDTGVSASTAYSYSVRAKDAAGNVSAGAPAAQVTTEAGGGTGTGALKAEYRNTDGSPTD
                     NQIRMSLRLVNTGSAAIDLSTVTARYWFTPDGGASTFATACDYAVLGCGSVTHGVRSAG
                     APATGASHYLEVGFGSGSLAAGATTGEIQLRINKSDWSAFQESDDYSRSTNTAFADAPR
                     IGVFTGSTLAWGTAP"
     gene            complement(6635..8564)
                     /locus_tag="B9W61_RS35580"
                     /old_locus_tag="B9W61_35550"
                     /pseudo=""
     CDS             complement(6635..8564)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766648.1"
                     /locus_tag="B9W61_RS35580"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35550"
                     /product="HtaA domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSMPRRGRLAALAALTVVSVGAGVLAVPASAAPGVHAAARAEAGG
                     TTSAAAPILVTGRSSWGFKDSWVRYVTGMGGSVERGRRRERGRGRTGRLSRQARLGGPC
                     PALGRCALRRLGHLRGPESRDNRHHARQPACRPQGRQGHAPHGRDDRHRRRPGPGDHAR
                     RAARRAHGVRRRPRRNRPRLDGHHGRAHRRGLDHLRLPGPAHVPGRHGAGPRRHQRRRQ
                     RPDADGQPGQRAGRRERGHRQRQGLPARARRVSGAVHRPARHHLPQRLRQRGVHPSGRR
                     GRHLQHHAEAHRDLHPLRGPRSRLPHHRLLRHELQLARRR"
     misc_feature    complement(7005..7007)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8554..8567
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.85"
                     /tool="antismash"
     misc_feature    8694..8712
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 31.03"
                     /tool="antismash"
     gene            complement(8716..9891)
                     /locus_tag="B9W61_RS35585"
                     /old_locus_tag="B9W61_35555"
     CDS             complement(8716..9891)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152514.1"
                     /locus_tag="B9W61_RS35585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35555"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_087767654.1"
                     /transl_table=11
                     /translation="MTYTEASMNALRQRGDELADATVATLFDRGEVGTFNSLMRYVSTA
                     GAPLPDGLPDVARDYLQATSAPPAWVDWEEMEKARLFFIDNNVHISTALSFASMPACYV
                     VPHVAKLLSATHGLSYPSKRMAETGQFTVYLMRPDAFEAGGRFIPAAQKVRLLHASIRH
                     HLLRERRWDTEALGTPICQEDMIGGQMFFSLLVLDSLHRLGIHMSEEGAAAYYYAWRVV
                     GAMLGVSQESVPRSLEEARRFLDLYMIRHMGPSEEGALLTRQLIDLYEEVVPGTFFDPI
                     VSALVRHLVGDTCADWLRVPRTSWDTAVKAVPHLLGVLETVEDRSPLGAWALDRLGHLT
                     TVLELSSLTRGRVMHYAIPEQLKEEYGVPGGASRSRWKPPSVTVPGDTPPW"
     gene            complement(10001..11056)
                     /locus_tag="B9W61_RS35590"
                     /old_locus_tag="B9W61_35560"
     CDS             complement(10001..11056)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956355.1"
                     /locus_tag="B9W61_RS35590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35560"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_087767655.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.5e-34, bitscore:
                     116.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADRWDAAVFKARVDEELHPFVAREADLFAAIDPSLAPVAAQVE
                     AAVADGKRLRAAFCYWGWRAAGQPDSAALVRAAASLELIHAAAVVHDDLIDDSALRHGR
                     PTAHIALRGAVRRRPHSVAAARSLAMLVGDLLMGMAGQLFTTSGLPAAYLGRARPLWTV
                     LGRELIAGECLEILRTGAEPDTGTSLKVIRYKTAKYTVEQPLLIGGALAGAGGRLREGY
                     SAYGLPLGEAFQLRDDLLGLFGDPERTGKANADDVRGHRPTALLAETWRVAGDDDRDRL
                     RALLGRRDLDEDGLHAVRDVMRRLKTPGLVEDMITARVAEALDALHELDVPSHAAAALT
                     ALANSATVRLS"
     gene            complement(11046..11324)
                     /locus_tag="B9W61_RS35595"
                     /old_locus_tag="B9W61_35565"
     CDS             complement(11046..11324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240940.1"
                     /locus_tag="B9W61_RS35595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35565"
                     /product="polyprenyl synthetase"
                     /protein_id="WP_087768115.1"
                     /transl_table=11
                     /translation="MTREAGRDGDLDERVVLLVAGAADLAVSAVGSALGAVRGLLRRSD
                     VGDLAAEAEHELTARGRLVLDRYAAPPPAHLELLARHVVARRASDDG"
     misc_feature    11359..11374
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(11529..12674)
                     /locus_tag="B9W61_RS35600"
                     /old_locus_tag="B9W61_35570"
     CDS             complement(11529..12674)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956352.1"
                     /locus_tag="B9W61_RS35600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35570"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_047174923.1"
                     /transl_table=11
                     /translation="MNEALLRSLTPSVLGILVRRGADFAAAEDAVQDALVEAVRTWPDE
                     QPRDPKGWLVTVAWRRFLDATRAEAARRRREDLVDEEPAPGPVPAADDTLQLYFLCAHP
                     SLTPSSAVALTLRAVGGLTTRQIARAYLVPEATMAQRISRAKRTVSGVPFDRPGDVATV
                     LRVLYLVFNEGYSGDVDLAAEAIRLTRQLAASIDHPEVAGLLALMLLHHARRATRTAPD
                     GSLVPLAEQDRGRWDTGAITEGVGILQAALARDRLGEFQAQAAIAALHADAPTAEETDW
                     VQIVEWYDELAGLTDSPVVRLNRAVAVGEADGPRAGLAELAALSDTLPRHTAVAAYLHE
                     RDGDLPTAARLYAEAAHKAPTLAERDHLTRRAARLNTGLRR"
     gene            complement(12682..13089)
                     /locus_tag="B9W61_RS35605"
                     /old_locus_tag="B9W61_35575"
     CDS             complement(12682..13089)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003945999.1"
                     /locus_tag="B9W61_RS35605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35575"
                     /product="YciI family protein"
                     /protein_id="WP_047174922.1"
                     /transl_table=11
                     /translation="MAKYLLLKHYRGAPAAVNDVPMDRWTPEEISAHMRYMQDFADRLE
                     KTGEFVDGSALAPEGAWVRYDGEGRPPVTDGPFAETKDLIAGWMIIDVDGYDRAVELAG
                     ELSAAPGAGGKPIHEWLEVRPFLSAPPTVTE"
     misc_feature    complement(13123..13132)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    13182..13197
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.87"
                     /tool="antismash"
     gene            complement(13222..14430)
                     /locus_tag="B9W61_RS35610"
                     /old_locus_tag="B9W61_35580"
     CDS             complement(13222..14430)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057045.1"
                     /locus_tag="B9W61_RS35610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35580"
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="WP_087767656.1"
                     /transl_table=11
                     /translation="MRVLLVGAGGVGTAITRIAARRAFFDHMVVTDHDLPRAEAAVAAL
                     GGEETRFTALRIDASDRAAVTALLTEQRCDILLNATDPRFVMPLFEAALAAGVDYLDMA
                     MSLSSPHPERPYEQCGVKLGDRQFERAAAWEEAGRLALVGVGVEPGLSDVFARYAADEL
                     FDEIEEIGVRDGANLTVEGYDFAPSFSIWTTIEECLNPPVVWERDRGWFTTAPFSEPEV
                     FDFPEGIGPVACVNVEHEEVLLIPRWVESRRVTFKYGLGDEFIETLKTLHSLGLDRTDK
                     VTVPGGEVSPRDVVAACLPDPASLGALMRGKTCAGTRVTGTKDGAPRDVYLYHVVDNQW
                     SMREYGSQAVVWQTAINPVIALELVASGVWGGAGVLGAEALAPRPFLDLLVAYGSPWGL
                     REQ"
     misc_feature    complement(14506..14519)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.16"
                     /tool="antismash"
     gene            14675..15481
                     /locus_tag="B9W61_RS35615"
                     /old_locus_tag="B9W61_35585"
     CDS             14675..15481
                     /NRPS_PKS="Domain: Abhydrolase_1 (21-125). E-value:
                     3.6e-14. Score: 44.9. Matches aSDomain:
                     nrpspksdomains_B9W61_RS35615_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158131.1"
                     /locus_tag="B9W61_RS35615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35585"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_087767657.1"
                     /sec_met_domain="PF00561 (E-value: 8.1e-09, bitscore: 34.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.6e-23, bitscore:
                     81.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEYADLPGVRTWYETEGTGDPLVLLHGGFCTNDTWGALRADLAA
                     AHRVYLPERRAHGHTADVAGPLTYQDMADDTVAFLEEVVGGPAHLVGWSDGGVVALIVA
                     GDRPDLVRKAVAIGANFRPGPECFVEPSMLDTMTPFGPDLAFFRELYEPVSPDGAGHWP
                     VVAEKVIDMWRTQPALTAEDLARVGAPTLVMAGDDDLMTLEHTTALYRAVPDAELAVVP
                     GASHLVPLEKPALVGRLILDHLAQEAVETMMPIRRAETGAPEGTGT"
     aSDomain        14738..15049
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W61_RS35615_Abhydrolase_1.1"
                     /evalue="3.60E-14"
                     /label="B9W61_RS35615_Abhydrolase_1.1"
                     /locus_tag="B9W61_RS35615"
                     /protein_end="125"
                     /protein_start="21"
                     /score="44.9"
                     /tool="antismash"
                     /translation="PLVLLHGGFCTNDTWGALRADLAAAHRVYLPERRAHGHTADVAGP
                     LTYQDMADDTVAFLEEVVGGPAHLVGWSDGGVVALIVAGDRPDLVRKAVAIGANFRPGP
                     "
     CDS_motif       14930..14986
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9W61_RS35615_0001"
                     /evalue="9.20E-06"
                     /label="NRPS-te1"
                     /locus_tag="B9W61_RS35615"
                     /protein_end="104"
                     /protein_start="85"
                     /score="18.2"
                     /tool="antismash"
                     /translation="GPAHLVGWSDGGVVALIVA"
     gene            complement(15508..15999)
                     /locus_tag="B9W61_RS35620"
                     /old_locus_tag="B9W61_35590"
     CDS             complement(15508..15999)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459124.1"
                     /locus_tag="B9W61_RS35620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35590"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_087767658.1"
                     /transl_table=11
                     /translation="MPAQDRAAQPSAGPSTSPGDPDQRLGFLLAYHGNATQTLIHKALA
                     ATGLTPRHMMTLLQLADGPVTQKALIERLGVDPSVLVALLNDLEGDDLVRRRRDTADRR
                     RHIVEITPRGASQLRTSETALQTVEHELFTDLSERDLATLRRLLGKLRTSPQDFSCTEE
                     "
     gene            16026..16445
                     /locus_tag="B9W61_RS35625"
                     /old_locus_tag="B9W61_35595"
     CDS             16026..16445
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382334.1"
                     /locus_tag="B9W61_RS35625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35595"
                     /product="DoxX family protein"
                     /protein_id="WP_087767659.1"
                     /transl_table=11
                     /translation="MEPRKSFIVINDSVIHIIDDPEVTMFIAYAVVGVLLALALGASAV
                     LTFTRNEAITATMGKVGVPGTWFPWLASLKAAGALGLLVGLGVPLIGSAAAIGVFLYFV
                     GAVVTHLRVKDYEIAPPVVLALLAAAALVLRVLSA"
     misc_feature    16035..16049
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
     misc_feature    16037..16048
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.71"
                     /tool="antismash"
     misc_feature    complement(16045..16058)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.77"
                     /tool="antismash"
     gene            16575..17159
                     /locus_tag="B9W61_RS35630"
                     /old_locus_tag="B9W61_35600"
     CDS             16575..17159
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971263.1"
                     /locus_tag="B9W61_RS35630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35600"
                     /product="DUF998 domain-containing protein"
                     /protein_id="WP_087767660.1"
                     /transl_table=11
                     /translation="MRSAPWWALVSSGCAPVLLTGSWMIAQLRQGPAYDPARQTLSVLA
                     SYGAASYWLMTGMLLALGTCYVVTAHALRPAAPAGRVALAGGGLCALALTLVPAPSSGG
                     ALEHGAVAAVGLVLLAVWPPLAAVRDRKPVPWGLRLDVSLAASALMCASALWFLAELQS
                     ARAPGVAERVVTFVQALWPFLVVVSCRRNAT"
     gene            complement(17195..>17383)
                     /locus_tag="B9W61_RS35635"
                     /old_locus_tag="B9W61_35605"
                     /pseudo=""
     CDS             complement(17195..>17383)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006350621.1"
                     /locus_tag="B9W61_RS35635"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35605"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VRTGAGRPFVRVDDEITDIDRAWVAVHHPGPALLHRVDPRRGPAD
                     HDYTVVGAWLRGVAGDV"
     gene            complement(17430..20426)
                     /locus_tag="B9W61_RS35640"
                     /old_locus_tag="B9W61_35610"
     CDS             complement(17430..20426)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971264.1"
                     /locus_tag="B9W61_RS35640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_35610"
                     /product="family 16 glycoside hydrolase"
                     /protein_id="WP_087767661.1"
                     /transl_table=11
                     /translation="MHPRPFHRCRRHLTGLLVSAFLVGAFSAAPAAAAPVPLDELPPQE
                     PGVTLRVFDVQVPLSELCDIKAGQTPNVDKLMPGIDWSSPDDFGFGDHFVSQVTANLTV
                     PEDGAYAFRLTSDDGSRLRIDGFTVIDHDGLHGAEPKDGTVELTAGHHPLRIDHFDRAG
                     GQQVTLEWKPPGAGDFAVVPTSVLSTDADVVRVTAPGRKECEGVLDSPGDGLPLAGTHP
                     DYALTDLRPAGFEPQVTAMDWLPDGRLAVTTWGGTDNTTGEVYLLDNVQGDTGPGEVTA
                     KKVAEGLKEPMGIKAVDGKLYVSQKHELTELTDADGDDVTDGRRTVATWPYGGNFHEFA
                     FGLLYRDGYFYLNLSVAIDLGGATTDPQPAPNRGSTIKVNKETGEVDYIAGGLRTPNGI
                     GWGPEDDMFVLDNQGGWLPSSKLLHIKQDRFFNHYTNPSGPFDAKPVTKPVLWLPQNEI
                     ANSPSTPLLLDEGRFAGQMLFGDVTYGGIQRAYLEKVDGEYQGAVFRFTQGLEAGVNRI
                     STGPDGAIYAGGLGAGGNWGQEGKLTYGLQKLSPSGDKAFDILAMRAKPGGFELEYTDP
                     LSEETAAKLAESYRVEQWTYAPTPAYGGPKIDEESLDVGAATLSEDRKKVTLTIPGLKA
                     NRVVHVRSPRPFSSADGTELWSTEAWYTLNSLPGDQPPATRYEAEEAALSGGAGFDTEH
                     AGYSGGGFVDNFGNEGAAVAFDVEAGKAGTHDVGLRYSNGPDPAPGTKTVSVHVNGEKV
                     RQIELLSTTDWKTWSTGTEQLELRKGRNTITYSFDSGDTGHVNLDMITVHPKGARVQLF
                     DGTDQAAWQHPDGRTPEWPVGGGEMEVAGGDLRTKQGFQDFRAHVEFWLPNLPPDVTGQ
                     DRANSGVYLQERYEVQILDSYGDTTLADNEAGAIYTKKAPDVNAATAPETWQTYDITFR
                     AARFDASGAKTEDARVTVVWNGVTVHDDVAVDGTTGGGAAEGPTAGAIRLQDHGSKVRY
                     RNVWVEPLT"
ORIGIN
        1 ccgacgccga cgaccggtac gcccgtgaac tgaccgcgtt gaggctggcc gcaggagccg
       61 atccggccgt ggtgcccgca ctgctgggca ccgcccccgg cgaccgggtg ctggtcctgg
      121 agcatctgga ccaccaacac cccaccggcg actggatcgt ggactacgcg gcggcactgg
      181 cccggctgca tgccgtcgcc cgccccgagc acaccggaat gctgccccgc tggcagggcc
      241 cggacgaggc cgacgccgcc tccttcctcc ggctggccgc ggccctcgac gctcccgtcc
      301 ctcccggagt gcccggggag ctcgacggcc tcgtggaccg gctcgcccgg gcgccggtgc
      361 acgccctgct ccacggcgac ccgtgccccg gcaacgacct gcacaccgcc gacggaaccc
      421 ggttcatcga cttcgaacag gcctcactgg gcagcgggct gatggaactc gcctacctgc
      481 gcatcggctt cccgacctgc tggtgtgtca ccgcggcccc cgccccgctg ctggaacggg
      541 cggaggccgc ctaccgcacg gcatggcgca ccgagaccgg cgacgaactc cacggcgacc
      601 tcaccgaccc ctgcgccggc tggctgatca ggggagacgc cctggtccga agagcccacc
      661 gcggaggcac cgatcacctg gcccggattc cggtccgcga ctggaagtgg ggcacggcga
      721 ccgcccggca acgcctcgtc caccggctcg gtgtcgtcgg cggcatgacc tccggccacg
      781 acggtctgag cgggctgagc accctctgcg cggacatgcg tcggcagctg ctcgcccgct
      841 ggccccggct ccgacccgtc cccgcggaac gcccctgagc cgaggccgct cgcggcccgg
      901 gccgacggcc accgatgcgg ggaagccgag gcggggcgtc ggtgggcggg ccgggttcga
      961 cggctggcgt caacgggccc agcccggtgt ccaggcgtcg gccggcgact ccggccgcgc
     1021 tcgtacgagg taccggcgca gcgccgccag aaccggatgc gggttgcccg tgcggtacag
     1081 gaacacgtgc ggatagaccg gcgtcgggcc caccaccggg atccgcctca ggtcatgagc
     1141 ggccggccac acgtatctgt cgcgggagcc gacgagcgtg gccagcgcgg cggagtcggc
     1201 gatcgagtcc atcagcgcct cggtcccgaa gtcgggcccg accgcgtcga tgcgcagacc
     1261 gaagtcctcc gccagccggt cgtagtaggc ggcccactcg gtgccctgct tgatgcccgg
     1321 gatccagatc cggtgcccgg ccaggtccgc cggggccaac gaccgggcgg aggccagcgg
     1381 atggcgcggc ccgaccagga gctgcaacgg atcgtccagg acgcgttcgg cgctgatccc
     1441 gtcgggcagc gcacccacgg gaacggcgcg gaaggtcgcg tcgatctcgc cggcccgcac
     1501 cgcctcggcc gcccccgtca cgttcctgtc cgcgagcgtc accacgtcca ggtccgtgcc
     1561 ggggtgggcc tggtagaagc cgcgtacggc cagcgccggg gcgatacgcc ggtgcaacac
     1621 gtccacgcgc agcacccggt cccccggacg taccgaggcg gcggcccgct ccacggcccg
     1681 cagcacctca cgggcgtggg gcaggaacgc ctgcccgtcc gcggtggggt gcgctccacg
     1741 ggcggtacgg acgaacaacg tcaccccgag cacacgttcc aggcccgcca cgcgcttgga
     1801 gacggcctgc tgactgacgc gcagctccac ggcggcttcc tggaactgtc cggtgtccgc
     1861 gacggtgacg aacgtgcgca cggcttcgat gtccacgccc tgaaccctat ggggccacaa
     1921 cgcagggtcg tggcacaccg acagctgggt cgtcggatca gggcgcccgc gcgcaccttg
     1981 ccccactggc ataggctcat gctcatgacg caagaagacg gtgagctgga cagcctggta
     2041 cgcaaacgca tccgcgccct gcgcgtggcc cagggctggt ccctggagga gctggccggc
     2101 cgcgcgaagg tcagtcagtc cacgctcagc cgcatcgaga acggccgacg ccgactggcc
     2161 ctggaccagt tggtcacgct cgcccgcgcc ctggacacct ccctcgacca gttggtcgag
     2221 accgcctccg acgacgtcgt ctccaacccg acgatcgacg gggcccacgg tcagatgcgg
     2281 tggcccatca aggcggaacc cggcctgacc gtcatccgtc agcgcttgac cgagccgccg
     2341 cccgacaacc cttcacgcct ccgcgcgcat ccgggccgcg agtggctcgt cgtcctctcc
     2401 ggcaccgcga tcctgctcct gggcaaccgg cgcctgcgga tcgagacgaa ccaggcggcg
     2461 gagttcccca cgatgctccc gcacgcgatc ggcgccgagg gcgggccgtg cgaactgctg
     2521 gggatcttcg accgggacgc ccgccgcggc caccagcgcg gcgaaggcgc ggagcaggcg
     2581 aaccgcccga ctccgccgcc cgggcggagc ctgccgtgac gagcgccggg ccctgatcgg
     2641 gcgtgcccgc cgcacgatcg gggcccgagc gccctcgcat acgcccggac cgggtgacgg
     2701 ggcccgccga tcgtcatgac cggcgggccc ggtgccggtc cgcgcggccg gcctgccgcg
     2761 cgtttcagcg gctcacgcgg ggtcgacgcg ggagatcacg ccattgctgc cgaggacgta
     2821 cagctcgccg tcaccgccct cggcgaacga gatcacctca ccgccgctga ctccgaggtc
     2881 gccgacgccg gtcacctcgc cgtccgtcat ccggagcgtc cgcagggtgc cgtcgcagta
     2941 gtcgctgaac acatagctgc cccgcaggtc cgggagcgcg tcgccgcggt agacgaatcc
     3001 gccggtcacc gagcagccga ggcccgtacg gtcgtactcg tacaccggcg ggacgtggtt
     3061 cgcgggctcc gtgccgcccc ggaaggggtg ggtgccctcc atggaggccc agccgtagtt
     3121 ctcgccgccc tcgctgtccg ccggggccca gtcgatctcc tcccagtcgc tctggccgac
     3181 atcgccgatc agcaggtcgc ccgtgcccgc gtcgaaggag aaccgccacg ggttgcgcag
     3241 cccgtacgcc cagatctcgt ccttcgcgtt cgcgtcgtcc acgaacgggt tgtccgcggg
     3301 gacggcgtac ggctcgccgc cggtcgggtc gatccgcagc agcttgccga gcagggtatc
     3361 gagcttctgc ccgttgccgt gcgggtcgcc gcccgagccg ccgtcaccga aggcgatgta
     3421 caggtagccg tcggggccga acttgatgtc cccgccgttg tggttcgcgt acggctgggt
     3481 ctgggtgagg accgttcgcc gtgtctccgg ctggagttgg ccgccctcca ccgcgaactc
     3541 gtcgatcgtg ctggtgcctt cgaggtcggt gtacgagatg tagaagtgcg cgaacgtctt
     3601 gtcgaacgcg acgcccagca ggccgcgttc gccgtccgtg gtggtctcgt cggagatgtc
     3661 gagcacgggt gcgccgaggc cctggtcgtc cagcaccctt acggtgcccg cgcgttcggc
     3721 gatccacagc gtgtcatcgg ggccggccgc cccggcggac ggaccctggg ccctggccac
     3781 ttcggtcagg gacgcgctca ccggcttgac cggatctgcg ggctcgacgg ccgacgccga
     3841 ggccagggcc agggacgtga cgaggcagag cgtgccgatg atcgccgagc ttctggtgcg
     3901 aaatttcacc gtggcctcct ggaggcggcg aaggggggag gtcacccggc tgctcgagcg
     3961 gagttgagtg gggggcgcga gccggcaggc aacctgggtg ggggagttgg tgtgtcaccg
     4021 gctacaggcg aggatagggg gacggacgtg gtctggccta gaccagcgtt acggcatctt
     4081 cttccgcggt gacgagcgcg gcctccgcaa gtcggtagtc ggccaaatcg tcgacgcgaa
     4141 cgcgaccggt gatgcactcg tgccgccacc gcaggctgat atgggagcgc tccaacactc
     4201 tccaactggc cctccgcgca aggttattgc gctgcactgc ttgacagtcc tcgcctgccg
     4261 cgtcagtttg ggagcgctcc cacatgcacg cttcccccac ctgaacccct tacctcctga
     4321 gcgtcacgga cccctgaacc cgtccgtcga cacccccgac ggacgtacga gaggagcacg
     4381 gagccgcaat gagaagcaga ggcgccaccc cgcacgcacc gcacgcgttc cgcaggagag
     4441 cggccgccgc actgtccgca ctgatcatgg gtgcggcact cgcggtggcc gtacccggac
     4501 aggcgtcggc cgccgcccgc gtcgacaacc cctacgccgg tgccaccgcg tacgtgaacc
     4561 ccgactggtc cgcccgggcc gccgccgagc ccggcggcga agtcatcgcg gacgaaccgt
     4621 cgttcgtctg gatggaccgc atcgccgcga tcggcggcac tcccggcgcg cggggcctgc
     4681 gcgcgcacct cgacacggcc gtgagccagg gagccgacct cttccaggtc gtcatctaca
     4741 acctgcccgg ccgggactgc gccgcactcg cctccaacgg cgaactcggc cccaccgagc
     4801 tgggccgcta caaggacgac tacatcgacc ccatcgccga catcctcggc gaccccgcct
     4861 acgcgagcct gcgcatcgtc acgctcatcg aaccggactc gctgcccaac ctcgtcacca
     4921 acgccggagg gacccccggc tcgacgcccg agtgcgccac gatgaaggcc aacggcaact
     4981 acgagaaggg catcggatac gccctgcaca ccctgggtgc cctgcccaac gtctacaact
     5041 acgtcgacgc cgcccaccac ggctggctcg gctgggactc caacttcgtc cccgccgcac
     5101 agcagttcaa gaaggccgcg acgacggagg gcgccaccgt ctccgacgtc cacggcttca
     5161 tcgtcaacac ggccaactac tcggcgctca aggagccgca cttcgcggtg accgactccg
     5221 tgaacgggac cacggtgcgt cagtcgcgct gggtggactg gaactactac gtggacgagc
     5281 tctcgttcgc caaggccctg cgcacggaac tggtccgcca gggcttcgcc tccgacatcg
     5341 gcatgctcat cgacaccgcc cgcaacggct ggggcggctc ggaccggccc gccggtcccg
     5401 gaccgctgac cagcaccgac gcctatgtcg acggtagccg gaccgatcgc cgcatccacg
     5461 cgggcaactg gtgcaaccag agcggcgcgg gcatcggcga gcgcccgacg gccgcccccg
     5521 agccggggat cgacgcctac gtctgggcca agcccccggg cgagtccgac ggcagcagcg
     5581 agcccatcga caacgacgag ggcaagggct tcgaccggat gtgcgacccg acgtacaccg
     5641 gcaacggccg caacggcttc aacctcacgg gcgccctgcc cgactccccg gtggccgggc
     5701 actggttctc cggacagttc caggagctgc tccgcaacgc ccacccgccg ctggacggcg
     5761 gcagcggagg cgaggaggac acccaggcgc cgaccgtgcc cacgaacctg cgggtgacgg
     5821 ccaagtccag cagcagcgtc accctcgcct ggacggcgtc cacggacgac accggcgtca
     5881 cggggtacga catcctccgc gacggcgccc cggtggggac gacgaccgcg acgacctaca
     5941 cggacaccgg cgtgagcgcc tcgaccgcct acagctactc ggtccgggcc aaggacgcgg
     6001 caggcaacgt ctcggccggg gccccggccg cacaggtcac caccgaggcg ggcggcggca
     6061 ccggaacggg agcgctcaag gccgaatacc gcaacaccga cggatccccg accgacaacc
     6121 agatccggat gtcgctgcgc ctggtcaaca ccggttcggc cgcgatcgac ctgtccacgg
     6181 tcaccgcccg ctactggttc acccccgacg gcggtgcgag caccttcgcc accgcctgcg
     6241 actacgccgt gctcgggtgc ggaagcgtga cgcacggggt ccggtcggcc ggcgcgccgg
     6301 ccaccggcgc cagccactac ctggaggtcg gcttcggcag cggcagcctc gcggcgggcg
     6361 ccacgaccgg ggagatccag ctgcggatca acaagagcga ctggtcggcg ttccaggaga
     6421 gcgacgacta cagccgctcc accaacaccg ccttcgccga cgccccgagg atcggcgtct
     6481 tcaccggctc caccctcgcc tggggcaccg ccccctgacc tgaaccgccc ccggcacggc
     6541 atccgcccct gccactgccg ctgcccctct ccccggacga cgggagaggg gcagcggcgc
     6601 ggaggtgcgg aggccgggag ggacgggatc ccggtcagcg cacgtcgacc cggtcgccgg
     6661 agccgatcgt gcccagacgg gacgacgtgg ccttgaactg cgccttccag gtgccgtcct
     6721 tcttggcggt gaaccccttc gagaacacgc ccttgccgtt ggtgcgcacg gtcgccagct
     6781 tgctccactt gctggagccg tcggccttga acaggatgat cacggactgg ccggaggcgt
     6841 tcttccaggt gccgtccagg ctgcgcaggg tgcccttgac ggtgatggtg cgccccttgc
     6901 ggaccggctc gggggaggcg ttgaagccgg agacggccgt ccgcagcttg acgtccacgt
     6961 tgtcggagga gctgacggcc gcggcgcggt cggcggtccc cgcgtaacgg gcgcgccagg
     7021 tgccgtcctt gacggcggtg accgacgccg aggcgacgcc cttgctgctg gtggtgaccg
     7081 tggtggcccg gctccagctc ttgccgccct tggaccggaa ctcgatcacg acgggagtct
     7141 tggccagcgg acgccatacg ttgtccgtgg cggacgcggt ctggagcgtg gcgaccacct
     7201 tcagcttgga gcccttgccc accggctcgg gcgaggcgtt gaaggagacg atccgggtcg
     7261 gcacggcgga gaccgtgagc gtggcggccg acgtggccgt ctcaccggag gcgttgacga
     7321 agacggcacg gtagcggtgg ccgtcgaggg cggcggccgc cttcaccgac agggtggcgg
     7381 tggtggcccc ggggacggtg ctccaggtcg cgccgcggtc ggtgctgcgc tcccagcgga
     7441 ccgagtccgc gccggtcgcg gcggcggtga acgtgccggt cgcacccgag cggacggtac
     7501 gcgacgcggg gtgctgggtc acggtggcgg ccgggacctc gacgccgaac cggagcggct
     7561 gggcgacgtc ctgggcccgg gagggcatcc aggtggggtc accgccgtcg tgcgagttga
     7621 agctcgtgac gaagcaggcg gtggtgcggc agtcgactac gggggccccg gagggggtga
     7681 aggtctcggt gagcttcagc gtggtgctga aggtgccgtc cgcgccgacc tgacggatgt
     7741 acgccgcgtt gccgaagacg ctggggtagg tggtgccggg cagggcgatg gactgcgcca
     7801 gatacacgcc gcgcccgggc tggtagccct tgccgctgac ggtgacctcg ttctcggcgc
     7861 ccagctcgct gacctggctg accgtcagcg tcgggacgct gacgtcgccg ctgatggcga
     7921 cggggtccag cgccgtgccg gccgggtaca tgggccggcc ctggtaggcg aagatggtcg
     7981 agccctcttc ggtgagcgcg gccgtgatgc ccgtccagtc gaggacggtt ccgtcgaggg
     8041 cgtcggcgga cgccgtgagc gcggcgagcg gcacgccggg cgtggtcacc ggggcctggc
     8101 cggcggcgat gtcggtcgtc acgtccatgt ggagcgtgcc cttgccgtcc ttgaggacga
     8161 cacgcgggtt ggcgagcgtg atggcggtta tcccgtgact cgggaccgcg taggtgaccg
     8221 agccgccgaa gcgcacatcg gccgagcgcc gggcagggtc caccgagccg tgcttgacgg
     8281 gatagtcgac ccgtccggcc gcgtccgcgc tcgcgccgcc ggccacgttc aaccgagccg
     8341 cccatgccgg tgacgtagcg gacccaggag tccttgaagc cccaggagga ccggccggtc
     8401 accaggatcg gggcggctgc cgacgtcgtg ccgccagcct cggcccgcgc ggcggcgtgg
     8461 acgccggggg cggcggaggc gggaacggcg aggacgcccg cacccacgga tacgacggtc
     8521 agggcggcga gtgcggccag gcggccgcgg cggggcatgg acatgcgctg catgtctcct
     8581 tcgggagagg ggcacggcgc acgtctggac ggagccgttc ccgggaggcg aacgaaagaa
     8641 ggggggatac cggcttctcg gcgtgtgggg acccgaagac gactcatcga atattaggtg
     8701 aggcttacct aattgtcacc atgggggtgt gtcgcccggg acggtgacgg agggcggctt
     8761 ccagcgggag cgggacgccc cgccggggac gccgtactcc tccttgagct gctcggggat
     8821 ggcgtagtgc atcacgcgtc cgcgggtgag ggaggacagt tcgaggacgg tggtgaggtg
     8881 gccgaggcgg tccagggccc aggcgccgag gggggaccgg tcctcgacgg tctccaggac
     8941 gccgagcagg tggggtacgg ccttgacggc ggtgtcccac gaggtgcgcg gcacccggag
     9001 ccagtcggcg caggtgtcgc cgaccaggtg gcggacgagc gcggagacga tcgggtcgaa
     9061 gaaggtcccg ggtacgacct cctcgtagag gtcgatgagc tgccgggtca gtagcgcgcc
     9121 ctcctcggac gggcccatgt gccggatcat gtacaggtcg aggaaccggc gggcctcctc
     9181 cagggaccgg gggacggact cctggctgac gcccagcatc gccccgacca cacgccaggc
     9241 gtagtagtag gccgcagcgc cctcctccga catgtggatg ccgaggcggt gcaggctgtc
     9301 gagcacgagc agcgagaaga acatctgccc gccgatcatg tcctcctggc agatgggcgt
     9361 cccgagcgct tcggtgtccc accgccgctc gcgcaggagg tgatggcgga tcgacgcgtg
     9421 cagtagacgg accttctggg cggcggggat gaagcggccc ccggcctcga aggcgtcggg
     9481 ccgcatcagg tagaccgtga actggcctgt ctccgccatc cgtttggagg ggtaactcag
     9541 cccgtgggtc gccgacagga gcttcgccac gtgcgggacc acgtagcagg cgggcatgga
     9601 ggcgaacgac agtgcggtgg agatatgcac gttgttgtcg atgaagaaca gccgggcctt
     9661 ctccatctcc tcccaatcga cccaggccgg cggggcgctg gtggcctgga ggtagtcccg
     9721 ggcgacatcg ggcagcccgt ccggcaaggg agcgcccgcg gtggagacgt agcgcatcag
     9781 tgagttgaac gtgcccacct ccccgcggtc gaagagcgtg gcgacggtcg cgtcggccag
     9841 ttcgtcgccc ctctgacgca gggcgttcat cgaagcctcg gtataggtca agacggactt
     9901 ccttgtactc gatgcggtgc gaagtggtgc ggtgcgaagc gaagcggtgc ggtggagtgc
     9961 ggcgcgctgg tgcgggtgtg tgcggtgggc gggcgagggg tcaggacagc cggacggtcg
    10021 ccgagttcgc cagcgccgtc agggcggcgg ccgcatgcga cggcacgtcc agctcatgga
    10081 gcgcgtcgag ggcttccgcg acgcgcgccg tgatcatgtc ttcgacgagg ccgggggtct
    10141 tcagcctgcg catgacgtcg cgcaccgcgt gcagcccgtc ctcgtccagg tcgcgccggc
    10201 ccagaagagc ccgcagccgg tcacggtcgt cgtcaccggc gacacgccag gtctccgcca
    10261 gcagggccgt gggccggtgg ccgcgcacat cgtcggcgtt ggccttgccg gtccgttccg
    10321 ggtctccgaa cagcccgagc agatcgtccc tcagctggaa ggcctcgccc agcggcagcc
    10381 cgtaggcgga gtagccctcg cgcagccgac cgccggcccc ggccagcgca ccgccgatca
    10441 acaggggctg ctcgacggtg tacttggcgg tcttgtaccg gatcaccttc agcgaggttc
    10501 cggtgtccgg ctccgcgccg gtgcgcagga tctccaggca ctcgcccgcg atcagctccc
    10561 gccccagcac cgtccacaac gggcgggccc ggcccagata ggcggccggc agaccgctgg
    10621 tggtgaacag ctgcccggcc atccccatca gcagatcgcc caccagcatc gccagcgatc
    10681 gggcggcggc gacggagtgg gggcgccggc gtacggcacc gcgcagagcg atgtgcgcgg
    10741 tggggcggcc gtgccgcaga gcgctgtcgt cgatgaggtc gtcgtggacg acagcggcgg
    10801 cgtggatcag ctccagggag gccgccgccc gcaccagcgc ggcgctgtcc ggctgccccg
    10861 ccgcccgcca gccccagtag cagaacgccg cccgcagccg tttgccgtcc gcgacggctg
    10921 cctccacctg cgcggccacc ggagccagcg acgggtcgat cgccgcgaac agatcggcct
    10981 cccgggcgac gaaggggtgc aactcctcgt cgacccgggc cttgaaaacc gccgcgtccc
    11041 accggtcagc cgtcatcgga ggcccgccgg gcgacgacgt gccgggcgag cagctccaga
    11101 tgggccggcg gcggggcggc gtaccggtcc agcaccaggc gcccgcgcgc cgtcagctcg
    11161 tgctctgcct ccgccgccag gtccccgacg tccgagcggc gcagcagccc gcgtaccgcg
    11221 cccagggccg aacccaccgc gctcaccgcc agatcggccg cccccgccac gagcaggacc
    11281 acccgctcgt ccaggtcccc gtcacgcccc gcttctcgcg tcatgcctct ccccacctcg
    11341 tcactgccga cggcgcaggt cacgcgcccg tcccacagca tcgcgaggca ccgggagccg
    11401 aaggggcgga agtcacgatc gagtgcgcaa ctcgctcggc cgtgcggttc cacgacggcc
    11461 tcggtgaggc gtacgcagga ccgccccgcc catcgcaccc gcggatgcga cgggcgcggt
    11521 ccgatccgtc agcgccgaag gccggtgttg agccgggcgg cccggcgcgt gaggtggtcg
    11581 cgctcggcga gcgtcggggc cttgtgggcg gcctccgcgt acagccgggc cgccgtcggc
    11641 aggtcgccgt cgcgctcgtg gagatacgcc gccaccgccg tgtgacgggg caacgtgtcg
    11701 ctcagcgcgg cgagttcggc cagcccggcg cgcggtccgt cggcctcgcc gacggccacg
    11761 gcccggttga gccggacgac cgggctgtcc gtcaggcccg cgagctcgtc gtaccactcg
    11821 acgatctgca cccagtcggt ctcctcggcg gtcggcgcgt cggcgtggag cgccgcgatg
    11881 gcggcctggg cctggaactc tcccagccgg tcgcgggcga gggccgcctg caggatcccg
    11941 acgccctcgg tgatggcccc ggtgtcccag cggccccggt cctgctcggc gagcggcacc
    12001 aggctcccgt cgggcgcggt ccgggtggca cggcgggcat ggtggagcag catgagggcg
    12061 agcagccccg ccacctccgg gtggtcgatc gaggccgcga gctgccgggt gagccggatc
    12121 gcctcggcag cgaggtcgac gtcgccggaa tagccctcgt tgaagaccag atagaggacg
    12181 cgcaaaacgg tggcgacatc gccgggccgg tcgaacggca cgccggagac ggtgcgcttc
    12241 gcccggctga tgcgctgcgc catggtcgcc tcgggcacca gataggcccg ggcgatctgg
    12301 cgggtcgtga gtcccccgac ggcgcgcagc gtgagcgcga cggcggacga cggcgtcagt
    12361 gacgggtggg cgcacaggaa atagagctgg agcgtgtcgt ccgccgccgg tacggggccg
    12421 ggcgccggct cctcgtcgac caggtcctcc cgccgccgcc gggcggcctc cgcccgggtc
    12481 gcgtcgagga accgccgcca ggccacggtg accaaccagc ccttcgggtc ccgcggttgc
    12541 tcgtccggcc aggtgcggac cgcctctacc agggcgtcct gcacggcgtc ctcggccgcc
    12601 gcgaagtctg ctccgcggcg gacgaggatc ccgaggacgc tcggcgtgag gctccgcagg
    12661 agggcctcgt tcatcgtggt gtcactccgt gacggtgggc ggcgcggaca ggaacgggcg
    12721 tacctccagc cactcgtgga tcggcttccc gcccgccccc ggagcggccg acagctcccc
    12781 ggccagctcg acggcacggt cgtatccgtc gacgtcgatg atcatccagc ccgcgatgag
    12841 gtccttggtc tcggcgaacg gcccgtcggt gaccggcggg cggccctcgc cgtcgtaccg
    12901 gacccacgcg ccctcggggg cgagcgccga gccgtcgacg aactccccgg tcttctccag
    12961 ccggtcggcg aagtcctgca tgtaccgcat gtgcgccgag atctcctcgg gcgtccaccg
    13021 gtccatcggt acgtcgttga ccgccgccgg ggctccgcgg tagtgcttga gcagaaggta
    13081 cttggccatg gtgctactcc tcggtcctgt gcggcccatt gtggccgcct tcactacggg
    13141 gacggagccg gacgcgggtt ctcgacatcg tcgcccgaaa cttctcgact tttttccggc
    13201 gggccgggga cgggcccgcg gtcactgctc gcgcaggccc cacggggacc cgtacgcgac
    13261 gagcagatcc aggaacgggc gcggggccag cgcctcggcg ccgagcacgc ccgcaccgcc
    13321 ccagacgccg ctcgccacca gttccagggc gatcaccggg ttgatggccg tctgccagac
    13381 cacggcctgc gagccgtact cgcgcatcga ccactggttg tcgaccacgt ggtacaggta
    13441 cacgtcgcgg ggcgcaccgt ccttcgtgcc cgtgacccgg gtgccggcac aggtcttgcc
    13501 ccgcatgagt gcgccgagag aggccgggtc gggcagacag gccgccacca cgtcacgggg
    13561 ggacacctcg ccgccgggca cggtcacctt gtccgtgcgg tccaggccga ggctgtgcag
    13621 ggtcttgagg gtctcgatga actcgtcgcc cagcccgtac ttgaacgtga cgcgccggga
    13681 ctccacccag cgcgggatca gcaggacctc ctcgtgctcg acattgacgc atgcgaccgg
    13741 accgatgccc tccgggaagt cgaacacctc cggctcgctg aacggggccg tggtgaacca
    13801 cccccggtcc cgctcccata ccaccggcgg gttcagacac tcctcgatgg tggtccagat
    13861 cgagaacgac ggggcgaagt catagccctc gacggtgagg ttcgcgccgt cccggacgcc
    13921 gatctcctcg atctcgtcga acagctcgtc cgccgcgtac cgggcgaaga cgtcggacag
    13981 ccccggctcc acgcccaccc cgacgagcgc gagccggccg gcctcctccc acgccgcggc
    14041 ccgctcgaac tgccgatcgc cgagcttcac cccgcactgc tcgtacgggc gctccggatg
    14101 cggcgaggac agcgacatgg ccatgtccag atagtcgacc ccggcggcca gcgccgcctc
    14161 gaacagcggc atcacgaacc gggggtcggt ggcgttgagg aggatgtcgc accgctgctc
    14221 ggtgaggagc gcggtgaccg cggcccggtc ggaggcgtcg atgcgcagag cggtgaatct
    14281 ggtctcctcc ccgccgagcg ccgccaccgc ggcctcggcc cggggaagat cgtggtcggt
    14341 gacgaccatg tggtcgaaga aggcgcggcg ggcggcgatc ctggtgatcg ccgtacccac
    14401 gccacctgcg ccgacgagca gtacgcgcat gccggatgtg cctttcgtcg gagggacggg
    14461 ccgtgaggac cggtgccctt ggattcgtcc gggcaagggg tgcgcttgag cggcgtcaac
    14521 gcggttggcg taacgacggg gccaggcagg ccacgggcca cgctccgccc gacccccgga
    14581 ggcaacagct cgggctccgc atggcggccc ccggggccac ggcgcagact ggccggagac
    14641 ggaaaaggcg actgccccgg agaggcctgg aacgatgggt gagtacgcgg atctgcccgg
    14701 cgtcaggacc tggtacgaga ccgaggggac cggcgacccg ctggttctgc tgcacggcgg
    14761 cttctgtacc aacgacacgt ggggcgcact gcgcgccgac ctcgccgccg cccaccgcgt
    14821 gtatctgccg gaacggcgcg cccacgggca cacggccgac gtcgcggggc cgctgacgta
    14881 ccaggacatg gccgacgaca ccgtggcctt cctggaggag gtcgtcgggg gaccggcgca
    14941 tctggtgggc tggagcgacg ggggagtcgt cgcgctgatc gtcgccgggg accggcccga
    15001 cctcgtccgc aaggccgtgg cgatcggggc caacttccgg ccgggccccg agtgtttcgt
    15061 cgagccgtcg atgctcgaca cgatgacgcc gttcgggccc gatctggcgt tcttccggga
    15121 gttgtacgag cctgtctcac cggacggcgc gggccactgg ccggtggtgg ccgagaaggt
    15181 gatcgacatg tggcgtacgc agccggcgct gacggccgag gacctggccc gcgtcggcgc
    15241 gcccaccctg gtcatggccg gcgacgacga cctgatgaca ctggagcaca cgaccgccct
    15301 gtaccgcgcg gtcccggacg ccgagctggc tgtcgttccc ggggcgtccc atctggtccc
    15361 gctggagaag ccggcgctcg tcggccgact gatcctcgac catctcgcac aggaggcggt
    15421 ggagacgatg atgcccatcc ggcgggcgga gaccggggcc ccggagggca ccgggacctg
    15481 agccggaggc gtcgaggacc gcggggctca ttcctccgtg cagctgaagt cctgcggaga
    15541 ggtccgcagc ttgcccagca gccggcgcag cgtggccagg tcgcgctcgg acaggtccgt
    15601 gaagagttcg tgctccacgg tctggagtgc cgtctccgag gtccgcagct gcgaggcgcc
    15661 ccgcggagtg atctcgacga tgtgacgtcg tcggtcggcg gtgtcacgac gacggcgtac
    15721 gagatcgtcg ccttcgagat cgttgaggag ggcgacgaga acgctggggt cgacgccgag
    15781 cctctcgatg agcgctttct gtgtgaccgg cccgtcggcg agctgcagga gcgtcatcat
    15841 gtgccgcgga gtcagcccgg tggccgcgag cgccttgtgg atcagtgtct gcgtcgcgtt
    15901 gccgtggtag gcgagcagga atccgaggcg ctggtccgga tcgccgggag acgtcgaagg
    15961 ccccgccgat ggctgggcgg ccctgtcctg agctggcatt ccaccacggt atcagggcac
    16021 acattgtgga acctaggaaa tcgtttatag tcatcaacga ttcagtcatt cacatcattg
    16081 atgatcccga ggtaaccatg ttcatcgcct acgccgtggt cggcgtcctt ctcgccctcg
    16141 ccctcggcgc ctccgccgtg ctgacgttca cgcgcaacga ggccatcacg gccacgatgg
    16201 gcaaggtggg ggtccccggc acctggttcc cctggctggc ctcgctcaag gcggccggcg
    16261 ccctcggcct cctggtcggc ctcggtgtgc cgctgatcgg atccgccgcc gccataggcg
    16321 tcttcctcta cttcgtcgga gccgtcgtca ctcacctgcg cgtcaaggac tacgagatcg
    16381 caccgcccgt ggtgctcgcc ctgctggccg ccgccgcact ggtcctgcgc gtgctgtcgg
    16441 cctgaacgtc cccagggggt gtctcacccg cgcgggcggc ggcgtgatcg gctgctctcg
    16501 ccggtggcgg cgcggtcggc cgaaagcagt cggatgtcag cagtgggcgg gatgttcaca
    16561 tttatgctga ctcgatgcga tctgctccct ggtgggcctt ggtctcctcc ggatgcgccc
    16621 ccgtccttct gaccggttcc tggatgattg cgcagctgcg ccaggggccg gcgtacgacc
    16681 ccgcgcggca gaccctgagc gtgctggcct cctacggcgc tgccagctac tggctgatga
    16741 cggggatgct cctggcgctg gggacgtgct acgtggtgac ggcgcacgcg ctccgcccgg
    16801 cggcgcccgc cgggcgggtc gccctggccg gcggcggact gtgcgcactg gccctgacac
    16861 tggtgcccgc cccgagcagc ggcggggcgt tggagcacgg ggccgtggcc gccgtgggcc
    16921 ttgtgctgct ggcggtgtgg ccgcccctgg ccgcggtccg ggaccggaag ccggtgccgt
    16981 gggggctgag gctcgatgtg tcgctcgccg cgagcgcctt gatgtgcgcg agcgctctgt
    17041 ggttcctggc ggagctgcag agcgcgaggg cgcccggcgt cgccgagcgc gtggtcacgt
    17101 tcgtccaggc gctgtggccg ttcctggtgg tcgtctcctg ccggagaaac gcgacctgac
    17161 cggggcgaag cccgaggagg cgacgggcac gcgcctacac gtcgcccgcc acgccccgca
    17221 gccaggcgcc gacaaccgtg tagtcgtggt ccgccgggcc tcgtcgggga tccacccggt
    17281 ggagcagggc ggggcccggg tggtggacgg cgacccacgc ccgatcgatg tcggtgatct
    17341 cgtcgtcgac ccggacgaac ggacggccgg cgccggtgcg gacggttccg gggcgacagc
    17401 gggccgctgc caccccggaa ccggcgcgcc taggtgagcg gctcgaccca cacgttgcgg
    17461 tagcggacct tgctcccgtg gtcctggagc ctgatcgccc cggccgtcgg accctcggcc
    17521 gctccgccgc cggtcgtgcc gtcgacggcc acgtcgtcgt gaacggtgac gccgttccac
    17581 acgacggtga ccctggcgtc ctccgtcttc gcgcccgagg cgtcgaagcg ggcggcgcgg
    17641 aaggtgatgt cgtacgtctg ccaggtctcc ggggccgtgg cggcgttcac gtccggggcc
    17701 ttcttggtgt agatcgcccc ggcctcgttg tcggcgagcg tggtgtcacc gtacgagtcg
    17761 aggatctgca cctcgtagcg ctcctgcagg tacacgccgc tgttggcgcg gtcctggccg
    17821 gtcacgtccg gcgggaggtt cggcagccag aactcgacat gggcacggaa gtcctggaag
    17881 ccctgcttgg tgcgcaggtc cccgccggcg acctccatct ccccgccgcc caccggccat
    17941 tcgggagtgc ggccgtccgg atgctgccag gccgcctggt ccgtgccgtc gaagagctgg
    18001 acgcgggcgc ccttcggatg gacggtgatc atgtccaggt tcacatgacc ggtgtcaccg
    18061 ctgtcgaagg agtaggtgat cgtgttgcgg cccttgcgca gctccagctg ttccgtcccc
    18121 gtcgaccagg tcttccagtc ggtggtcgac agcagctcga tctgccgcac cttctcgccg
    18181 ttgacgtgga cgctcaccgt tttggtgccg ggcgccggat ccggcccgtt ggagtagcgc
    18241 agacccacat cgtgcgtccc cgcctttccg gcctccacgt cgaaggcgac cgccgccccc
    18301 tcgttgccga agttgtcgac gaagccgccg cccgaatagc ccgcgtgctc ggtgtcgaag
    18361 cccgcgcccc cgctgagggc ggcctcctcc gcctcgtacc gggtggccgg gggctggtcg
    18421 ccgggcaggg agttgagggt gtaccaggcc tccgtgctcc acagctccgt gccgtcggcg
    18481 gagctgaagg ggcgcggcga acggacgtgg accacacggt tcgccttgag cccgggaatg
    18541 gtcagcgtga ccttcttgcg gtcctcggag agggtggccg caccgacgtc gagggactcc
    18601 tcgtcgatct tggggccgcc gtaggcgggc gtcggggcgt acgtccactg ctcgacccgg
    18661 tagctctcgg cgagcttcgc ggccgtctcc tcggagagcg gatcggtgta ctccagctcg
    18721 aaaccgcccg gcttcgcgcg catcgccagg atgtcgaagg ccttgtcacc actgggggag
    18781 agcttctgga gcccgtaggt cagcttgccc tcctggcccc agttgccgcc cgcgccgagg
    18841 ccgccggcgt agatcgcgcc gtccgggccc gtgctgatcc ggttgacgcc cgcctccagg
    18901 ccctgggtga agcggaagac cgccccctgg tactcgccgt cgaccttctc caggtaggcg
    18961 cgctggatgc cgccgtacgt gacatcaccg aacagcatct gcccggcgaa ccgcccctcg
    19021 tccaacaaca gaggcgtact gggggagttg gctatctcgt tctgcggcag ccacagcacc
    19081 ggcttggtca ccggcttcgc gtcgaacggg cccgacgggt tggtgtagtg gttgaagaag
    19141 cggtcctgct tgatgtggag cagcttcgag gagggcagcc agccgccctg gttgtcgagg
    19201 acgaacatgt cgtcctccgg gccccagccg atgccgttgg gcgtacgcag gcccccggcg
    19261 atgtagtcga cctcgccggt ctccttgttc accttgatcg tcgagccgcg gttcggtgcg
    19321 ggctgcgggt cggtcgtcgc cccgcccaga tcgatcgcca cggacaggtt caggtagaaa
    19381 tagccgtccc ggtagagcag accgaaggcg aactcgtgga agttcccgcc gtacggccag
    19441 gtcgccaccg tccggcgccc atcggtcacg tcgtcgccgt cggcatcggt cagctcggtg
    19501 agttcgtgct tctgcgacac gtacagcttg ccgtcgacgg ccttgatgcc catcggctcc
    19561 ttgagcccct ccgccacctt cttggcggtc acctcgccgg gaccggtgtc gccctggacg
    19621 ttgtcgagga ggtagacctc gccggtcgtg ttgtcggtgc cgccccaggt ggtcacggcg
    19681 agccggccgt cgggcagcca gtccatcgcg gtgacctgcg gttcgaagcc cgcggggcgc
    19741 agatcggtga gcgcgtagtc cgggtgcgtc ccggccaggg gcagcccgtc gccgggggag
    19801 tcgaggacgc cctcgcactc cttgcgtccc ggcgccgtca cccgtacgac gtcggcgtcg
    19861 gtgctcagca cggaagtcgg cacgacggcg aagtccccgg caccgggcgg cttccattcg
    19921 agggtgacct gctgcccacc ggcgcggtcg aagtgatcga tgcgcagcgg atggtgaccc
    19981 gccgtcagct cgacggtgcc gtccttgggc tccgcgccgt gcagcccgtc gtgatcgatg
    20041 acggtaaagc cgtcgatccg cagccgcgaa ccgtcgtcac tggtcaggcg gaaggcgtac
    20101 gcgccgtcct cgggaacggt gaggttcgcc gtgacctggg agacgaagtg gtcgccgaag
    20161 ccgaagtcgt ccggcgaact ccagtcgatg ccgggcatca acttgtcgac gttcggggtc
    20221 tgtccggcct tgatgtcgca cagctcgctg agggggacct gcacatcgaa gacgcgcagg
    20281 gtgacgcccg gttcctgtgg cgggagctcg tccagcggca ccggcgcggc ggcggccggc
    20341 gcggcggaga aggcgccgac gagaaacgcg gagaccagca gaccggtgag atgtctgcgg
    20401 caacggtgga acggccgtgg atgcattctt cctcctggcc cctcgcggcg aggggcacgt
    20461 cgcggcggtg ggtggggcca cccggcgccc gggggtgaac gttcggctcg tgcggtggac
    20521 agcgctgcgt ccggacaggg gctccggtgg ctgcgccgag aacagtagga ggcttctacc
    20581 ggcggcgtcc atacttcgtc accacagtgt tcaaagttcg caggtgttga tgcaaagtgc
    20641 ccaaacccct tgatgtgcaa ggcatatggc actccgtcag aacagaagga accccggctg
    20701 agccctccga cggcatatgt gtgatcgcac ccgacgccgg tgaagcgggc agcgcaggcc
    20761 cgcttcaccg gcacccctcg cccgccccct gcccacgcct cgtcggcgga cccgctcagg
    20821 tacgggcgcc tgcggcgttg ccgcgcgcag cgtcaggggc aggggcaggg cgaacgtgtg
    20881 tgtgctactg gccctcgcgg ccggaggcgg aggcgaatcc cagccaggtg tggcggttgc
    20941 cccaccagca ccagccgacc ttgggggcgt tgcgccgctc ccggccgtcc cgcccggtgc
    21001 cgttgctgat ccagatcgcc ggggtacgcg cgtccagggc gccgttcgcc ttccgc
//
