LOCUS       NZ_KZ195572            21044 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. CS057 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195572
VERSION     NZ_KZ195572.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS057
  ORGANISM  Streptomyces sp. CS057
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 265.32x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188345.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 02:40:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,152
            CDSs (total)                      :: 7,074
            Genes (coding)                    :: 6,991
            CDSs (with protein)               :: 6,991
            Genes (RNA)                       :: 78
            rRNAs                             :: 10, 6 (16S, 23S)
            complete rRNAs                    :: 10, 6 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 23 of 83
            Pseudo Genes (incomplete)         :: 71 of 83
            Pseudo Genes (internal stop)      :: 4 of 83
            Pseudo Genes (multiple problems)  :: 14 of 83
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:25:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2736955
            Orig. end                         :: 2757999
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195572.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..21044
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="19"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21044
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21044
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11044](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11044)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(1200..2081)
                     /locus_tag="B9W61_RS11165"
                     /old_locus_tag="B9W61_11150"
     CDS             complement(1200..2081)
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611287.1"
                     /locus_tag="B9W61_RS11165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11150"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_047178753.1"
                     /transl_table=11
                     /translation="MIGPLIAVTGATGAVGGRVARRLARTGVPVRLLGRDPARLPDLPG
                     ADHAPAARYGDAEAMRRALDGAHTLFLVSAHESPYRVREHTTAIDAAVAVGVERIVYVS
                     FQGAAPDATFTFARDHWDTEAHIRTAEIRHTFLRDNWYLAGLPAMTGTDGVLRGPGGDG
                     RVAAVAHEDIADAAAAVLLDEGTDHDDRVYDLTGPEAFTLAEAADELSRVTGRPVVYVP
                     ETREEAYASRAGYGAEDWEVAGWVTSYEAIAGGELAAVSDAVPTLTGHPAKSFAQFLVE
                     NPDSYRHLLPGG"
     gene            complement(2078..2428)
                     /locus_tag="B9W61_RS11170"
                     /old_locus_tag="B9W61_11155"
     CDS             complement(2078..2428)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959102.1"
                     /locus_tag="B9W61_RS11170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11155"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_056700642.1"
                     /transl_table=11
                     /translation="MTEPLLHLAEAPLWEAARGTGTYEMSTRGRTLQEEGFIHLSLPHQ
                     LPGVARMLYGDDDRDLVVLVVDPARLADPVRYEAMKPGGEEFPHLYGPLPVGAVVEVRP
                     WDGGRREEDEPQ"
     CDS             complement(2462..>2697)
                     /GO_component="GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966355.1"
                     /locus_tag="B9W61_RS36835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11160"
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_256967627.1"
                     /transl_table=11
                     /translation="TPTEPTPTPTEPTATPTEPTPTPTGHTPHPTHSPSHPGELPDTGS
                     RGGEWIIGSIAAALVAAGGTVLVATRRARRRTF"
     gene            complement(2462..>2699)
                     /locus_tag="B9W61_RS36835"
                     /old_locus_tag="B9W61_11160"
     assembly_gap    2700..2724
                     /estimated_length=25
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2725..3821)
                     /locus_tag="B9W61_RS11175"
                     /old_locus_tag="B9W61_11165"
     CDS             complement(<2725..3821)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019546145.1"
                     /locus_tag="B9W61_RS11175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11165"
                     /product="choice-of-anchor A family protein"
                     /protein_id="WP_256967882.1"
                     /transl_table=11
                     /translation="MEQKARRRGNAIRAAVTVATAAAMVGVLAPAAGADPLPGGLGPCL
                     GSSCPPSWNDPNNGPVEYFDSNINVYVGGDFLVREAAAEAEGKVVTLGRFDMDKRDGVS
                     QIYNVGIAGVGSRVPPPDGSDYLTAGGDVTIAEGERLLAEEGTHSGRVAYAGDLTGTVE
                     PATAPRFDEDAAAPYTELRPQLTEASHCYAYDGDEHREATGTWVKTGDLMTFTGDGSSA
                     IQIFDVDADLESEAGGNTGFVFNGIPEGATVLVNVYGSTRSVATFMGSFPNEGLRENLL
                     WNFPDATDLSMTGPAQFEGSVLVGQPTSTTVLSMSGTNGRFYTAGSLTHTSSGTSGGQE
                     IHAYPFDGDLPTCTPEPTPTPTEPTP"
     misc_feature    3853..3866
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.03"
                     /tool="antismash"
     misc_feature    complement(3880..3895)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.56"
                     /tool="antismash"
     gene            complement(3937..4935)
                     /locus_tag="B9W61_RS11180"
                     /old_locus_tag="B9W61_11170"
     CDS             complement(3937..4935)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458285.1"
                     /locus_tag="B9W61_RS11180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11170"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_256967628.1"
                     /transl_table=11
                     /translation="MRLLMLGGTEFVGRAVTDAALERGWDVTVFHRGRHAPPPGVSALT
                     GDRTEGPYGLAALAESGQDWDLVVDTWSGAPAAVRDAARLLSGRAGHFAYVSSRSVYAY
                     PAAPGLDENGPLVAGASPDDGADVPYDRAKRGGELAALDAFGDRALLARAGLIIGPWEN
                     IGRLPWWLTRIARGGPVIAPGRPGTELQYIDARDLADWILGAAAGGLHGAYNTVSRPGH
                     TTMGELLEACVRVTGADAELRWTDPEVLLAAGAEPWSDLPIWLPPGELYDTLHRGDHTR
                     AYAAGLRCRPAEETVADTWAWLRSLGGVAPQRPDRPVVGLDPLLEAKLLAL"
     misc_feature    complement(4938..4951)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            complement(5052..6005)
                     /locus_tag="B9W61_RS11185"
                     /old_locus_tag="B9W61_11175"
     CDS             complement(5052..6005)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959105.1"
                     /locus_tag="B9W61_RS11185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11175"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_047178749.1"
                     /transl_table=11
                     /translation="MELEVRHLRALCAIADAGSLHQAARRLGVSQPSLTTQLRRIENVL
                     GAELFRRERTGCRPTSLGRAVLSRARPLVDGMSDLVAEALAEAEAARPRGSRLRIGSTA
                     SRVIGGWLRRLRVALPGTDISLRVDVSAHALLRSVEEGRLDVAFVHEVEGSPLAVPERL
                     EQRVLVDREPQFISLSRDHPAARRRVVELGDLAGDPWMVDPTVDGEWDGVRRVLGAAGL
                     NPPVLHGDYLTAASLVVLGEAVAPCQPTSGPRDDMVIRPLLGDPLAVRLLLVSRPGTDI
                     AVVYAQLEDAYRDAARRASGYHEWLLRHRSPLARTP"
     gene            6320..6973
                     /gene="snpA"
                     /locus_tag="B9W61_RS11190"
                     /old_locus_tag="B9W61_11180"
     CDS             6320..6973
                     /EC_number="3.4.24.77"
                     /codon_start=1
                     /gene="snpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127499.1"
                     /locus_tag="B9W61_RS11190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11180"
                     /product="snapalysin"
                     /protein_id="WP_087764990.1"
                     /transl_table=11
                     /translation="MRHLRTAVATAAAGLGLVAALGTAPVVAAAPAPAAPSSTTIAAYN
                     GSGENAAANRAFLDAVMKSVAEKRAANPGIKAVTVTYNASSAPSFRGEIANSTQIWNSS
                     VSNVRLQEGSNADFTYREGNDPRGSYASTDGHGRGYIFLDYRQNQQYDSTRVTTHETGH
                     VLGLPDTYSGPCSQLMSGGGPGPSCTNAYPDANERARVNQLWQNGLAALARSAS"
     gene            complement(7107..7463)
                     /locus_tag="B9W61_RS11195"
                     /old_locus_tag="B9W61_11185"
     CDS             complement(7107..7463)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458277.1"
                     /locus_tag="B9W61_RS11195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11185"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_087764991.1"
                     /transl_table=11
                     /translation="MLFRVDPTSTVPLGDQIAASVRRAVADGAVVPGERLPAARVLAES
                     LGVNVHTVLRGYQRLREEGLIELRRGRGAAITADASPQRARLLERVREAVADARDLGMT
                     EDELLVLVRSELDA"
     gene            complement(7466..8434)
                     /locus_tag="B9W61_RS11200"
                     /old_locus_tag="B9W61_11190"
     CDS             complement(7466..8434)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061501.1"
                     /locus_tag="B9W61_RS11200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11190"
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_087764992.1"
                     /transl_table=11
                     /translation="MTSKNLGRATLAALPFVLALLVDLVLHVTVKDRLPARLAVHFDAG
                     GSANGYMGITAHLLYTVTSLLVLGALWAFIAANGKVYGRAHRWFIGGGFAVAAFLGYLM
                     IAVLFVNVDAPESGPDGGFPLWHIAVALGAGVLAGALGLLCSRLVPAVEDPRDTDPANR
                     ERIALADGEVAGWARGIGVWWAPIAVLVFLAAGVTVGLEVNWFVGVPLFLLALVAATFC
                     RPHVTVDRRGLTVSGLLPRPRVRVPLERMAGADSRRVNALAEYGGWGYRIRPERSGVIT
                     RSGEAIVVSLTSGREFAVTVDDSATGAALLNTLLDRQRTGR"
     gene            complement(8590..9258)
                     /locus_tag="B9W61_RS11205"
                     /old_locus_tag="B9W61_11195"
     CDS             complement(8590..9258)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959109.1"
                     /locus_tag="B9W61_RS11205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11195"
                     /product="DUF6304 family protein"
                     /protein_id="WP_047178745.1"
                     /transl_table=11
                     /translation="MTDESWAGWYRDTKGSDAVVLTTDGRQLRIRIRGVDFEGESFDGL
                     GPVAGPPPESGMFALADGALTDCVLEWDLPLPVLVAGTLRHATLSCLLSLRRVDPDLHL
                     ALHLDGAVYESARAERDFDTALATVQRILPDGVRIQTCVACAFSDYFPAPGRGLSGGLA
                     CFRGAKDAYRGSAGENDVRDLWDRRSGFVQEVWSCREFEVRPADGAGTGHRGAFPLELA
                     "
     gene            complement(9315..9911)
                     /locus_tag="B9W61_RS11210"
                     /old_locus_tag="B9W61_11200"
     CDS             complement(9315..9911)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959110.1"
                     /locus_tag="B9W61_RS11210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11200"
                     /product="N-acetyltransferase"
                     /protein_id="WP_087764993.1"
                     /transl_table=11
                     /translation="MGIRIQRAEQHDRELVVAVMEKAFHHDPVSCWVFPDEAHRRAVHG
                     RFLGVFVDVALAEGRIDIAEDGAAVALWLPVPAGAPEGEDPTPALMRRTADPDNERCEL
                     VGRLTGAVHPHDRAHAYLLMIGVTPDRQGEGIGAELIGAELERCDREGLPAYLEASSAR
                     SRVLYERLGFRLPGRAVELPDGPPMYPMWREPQAG"
     gene            complement(10001..11044)
                     /locus_tag="B9W61_RS11215"
                     /old_locus_tag="B9W61_11205"
     CDS             complement(10001..11044)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959111.1"
                     /locus_tag="B9W61_RS11215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11205"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_087764994.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.9e-60, bitscore:
                     201.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTDAATEGHEAAALLERTRAVVDPHLRSAVESLPGGIRRVAMY
                     HFGWENADGTPATGQAGKAIRPALVLAAARALGGDPERAVRAAVAVELAHNFTLLHDDV
                     IDEDTTRRHRPTAWAVFGIPDAVITGDAMLALAQRLLAEDAHPAAAPAVARLSSCIIEL
                     CAGQQADCAFEERGPDEVTLDECLAMATAKTGALLGCACALGALYAGAEDRAVRAMDGF
                     GREAGLSFQLIDDLIGIWGDPDRTGKPVGADLSAHKKSLPVVAALTSGTPAAAELAALY
                     RGPMTTSGEVSRAADAVDRAGGRDWAQVCAADRMARAVHHLSRAVPDPGAAGDLLALAE
                     FVTRRTS"
     gene            complement(11136..12542)
                     /locus_tag="B9W61_RS11220"
                     /old_locus_tag="B9W61_11210"
     CDS             complement(11136..12542)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966367.1"
                     /locus_tag="B9W61_RS11220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11210"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_087764995.1"
                     /transl_table=11
                     /translation="MSVGEEVRDTQAPPQQSLGTAAARNLATTTKSAPQMQEITSRWLL
                     KMLPWVQVQGGTYRVNRRLSYAVGDGRVTFVQTGGRVSVIPAELGELPALREFGDEEVL
                     AELARRCEQRDVAAGEVLAASGEAADRVFLLAHGKVAKIGSGPYGDETELGVLADGAYF
                     GDRSLIDGDAVWEYTARAVTSCTLLTLSRADVYNLAERAASLQDHLAGLLSIPRQRTNH
                     YGEAAIDLSAGHVGEAVVPHTFVDYEAAPREYELSVAQTVLKVHSRVADLYNQPMNQTE
                     QQLRLTVEALRERQEHELINNREFGLLNNCDYGQRLQPHDGVPGPDDMDELLSRRRGSK
                     LFLAHPKAIAAFGRECSRRGLVPESIDIGGHHVPSWRGVPIFPSDKIPVSDARTTSIIC
                     MRTGEAEQGVIGLHQTGIPDEIEPSLSVRFMGIDEKAIISYLVTAYYSAAVLVPDALGV
                     LENVEVGRRH"
     misc_feature    complement(12575..12589)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.32"
                     /tool="antismash"
     misc_feature    complement(12684..12700)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: medium, score: 26.86"
                     /tool="antismash"
     misc_feature    12695..12711
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.12"
                     /tool="antismash"
     gene            12719..13165
                     /locus_tag="B9W61_RS11225"
                     /old_locus_tag="B9W61_11215"
     CDS             12719..13165
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611275.1"
                     /locus_tag="B9W61_RS11225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11215"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_047178741.1"
                     /transl_table=11
                     /translation="MRLTRFTDVALRVLMRLAVAEDREPPTTREVAATMRVPYTHTAKV
                     VARLQHLGLLDARRGRGGGLTLTPAGRSASIGSLVRELEGPEEVVECEGDTPCPLRSAC
                     RLRGALRKAQDAFYATLDPITVADLVASPTGPLLLGIGSRPPPD"
     misc_feature    complement(13216..13229)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.3"
                     /tool="antismash"
     gene            13259..14455
                     /locus_tag="B9W61_RS11230"
                     /old_locus_tag="B9W61_11220"
     CDS             13259..14455
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127491.1"
                     /locus_tag="B9W61_RS11230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11220"
                     /product="globin domain-containing protein"
                     /protein_id="WP_087764996.1"
                     /transl_table=11
                     /translation="MLSDRSTATVRATLPAVGAAIGDIADLFYEKLFAAHPELLRDLFN
                     RGNQASGDQRRALAGSIAAFATQLVERPGTRPDVMLDRIAHKHASLGVTPAQYEVVHTH
                     LFAAIAEVLGDAVTPEVAAAWDEVYWLMAGSLTAVEERLYAQQGVLAGDVWHTWEVTAR
                     VEETEDVATFLLRPADDTPPPAFRPGQYVSVQVELPDGARQIRQYSLSSAPGSRLRSIT
                     VKRVRGQGTPDGEVSRHLHEHTRVGDLLRVSVPYGDLVLDHLDAPLLLASAGIGCTPML
                     SMLEHLVQEGHSGPVTVVHGDRSPADHALRTDHVRLTEKLPDAEAHFWYETPEAGQPAN
                     RTGLVDLEGITVRPGTHAYLCGPLPFMRAVRAQLLEAGVRPADVHYEVFGPDLWLASS"
     gene            14482..15411
                     /locus_tag="B9W61_RS11235"
                     /old_locus_tag="B9W61_11225"
     CDS             14482..15411
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959115.1"
                     /locus_tag="B9W61_RS11235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11225"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_087764997.1"
                     /sec_met_domain="PALP (E-value: 2.3e-17, bitscore: 62.0,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSPPRLDALLRPRVPSPLREVHDERFARHGVRLFLKRDDLIHPD
                     LPGNKWRKLALNLEAAAGRTVLTFGGAYSNHLRATAAAGRLLGFPTVGVVRGDELAHRP
                     LNPSLARCAADGMRLHFVDRTTYRAKASPEVLEGLLSLFGEVEVIPEGGSNALAAEGCT
                     ALGRELAGACDVAAVACGTGGTLAGLAAGLGPGQRALGIPVLRGGFLGREVERLQREAF
                     GGPSGNWSLDERFAFGGYARSTPELEAFAADFEDRHGLPVERVYVAKLLFALTALTAEG
                     AFAPGARVSAVITGTPDAPPPQDASVSR"
     gene            complement(15387..16988)
                     /locus_tag="B9W61_RS11240"
                     /old_locus_tag="B9W61_11230"
     CDS             complement(15387..16988)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510032.1"
                     /locus_tag="B9W61_RS11240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11230"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_087764998.1"
                     /transl_table=11
                     /translation="MDALPLIALVAVSAAVAGAARRTPVPAPLVLVAVGLVAGYLPGVP
                     TYHLDAHVVLPLLLPPLLHTAALDSSYLDLRANVRPVALLSVGYTLFATVAVGWLAHLI
                     IPDLPLTAALVLGAVIAPPDAVTAAAIARRVGLPSRVTTILQGESLVNDATAITAFKVA
                     LAAAVGEGMSWGAGIGEFLLAAVGGVGVGLLLMVPLHWLRTHLKEALLQNTLSLLIPFV
                     AYAAAERVHASGVLAVVVVALYLGHRSWQVDFATRLQEAAVWKMVAFVLESAVFALIGL
                     QLPFVLKGLGSFGVWEALGYAAIVFLVVVVVRFVWVYPATYLPRWLSRRVREREPGTDW
                     TAPLIVGWAGMRGVVSLAVAFSIPLVMLDGEPFPARSLVLFLTFTTVIGTLVIQGLTLP
                     VLVRVLKLPGPDPQTVTLVEAQAQNEASEAAEARLDQLLADPHSSLPPPLADRLRSVLE
                     RRRNSVWERLGAADPVTGESADDTYRRLSREMIEAEREVFVRLRDERRIDDEMMRTLLR
                     RLDLEEAAAYRETDAS"
     gene            17024..17284
                     /locus_tag="B9W61_RS11245"
                     /old_locus_tag="B9W61_11235"
     CDS             17024..17284
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="B9W61_RS11245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11235"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_047178737.1"
                     /transl_table=11
                     /translation="MSECAHVAELPRPEPAPLGETCPECLEAGSHPVQLRLCLTCGHVG
                     CCDSSPLRHATGHFRATGHPVMRSFEAGESWRWCFEDGSIV"
     misc_feature    17420..17440
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.43"
                     /tool="antismash"
     gene            17517..17930
                     /locus_tag="B9W61_RS11250"
                     /old_locus_tag="B9W61_11240"
     CDS             17517..17930
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="B9W61_RS11250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11240"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_003966375.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVDSTVADDRTVSISLYKQRGAGPGPA"
     gene            17954..18883
                     /locus_tag="B9W61_RS11255"
                     /old_locus_tag="B9W61_11245"
     CDS             17954..18883
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072101.1"
                     /locus_tag="B9W61_RS11255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11245"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_026290743.1"
                     /transl_table=11
                     /translation="MRDETIRSGVVRPAGIPEQQARPHPVDGADGPESIDVAVEQQSQA
                     GRAGQMSEHGHHDPHDRSGARALFFELRELPDGSAEKAELRNRLVRMHLPLVEHLARRF
                     RNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVP
                     RRLQELRLSLTTATAELSQQHGRSPTVHELAERLGISEEEVLEGLESANAYSTLSLDVP
                     DTDDESPAVADTLGSEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQ
                     EVGISQMHVSRLLARTLAQLRERLLVEE"
     misc_feature    17959..17973
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.11"
                     /tool="antismash"
     gene            complement(18926..19375)
                     /locus_tag="B9W61_RS11260"
                     /old_locus_tag="B9W61_11250"
     CDS             complement(18926..19375)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072100.1"
                     /locus_tag="B9W61_RS11260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11250"
                     /product="hypothetical protein"
                     /protein_id="WP_047178736.1"
                     /transl_table=11
                     /translation="MSTQATPSTPSPSAAERPTRITVLAGVNALEGLALALGGVYMLVM
                     GLLGKLESTQQAETVGITLVALGAIPLIAARGLLLLRSWSRGPALITQIMALPVAWTLL
                     RSQGALIPTGIALAVVAVTGLVLVLKPATTQDLGIRRGPRATPEA"
     misc_feature    19462..19475
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.28"
                     /tool="antismash"
     gene            19540..20508
                     /locus_tag="B9W61_RS11265"
                     /old_locus_tag="B9W61_11255"
     CDS             19540..20508
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="B9W61_RS11265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_11255"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_047178735.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRRAADSDDIDLVVALGGDGTVNEVVNGLLHRGPDVDNLPKLAVVPGGSTNVFARALG
                     LPNDAVEATGAILDALENRTERTVGLGLAAGTPGTEDESVPERWFTFCAGLGFDAGVIG
                     RVEQKREHGKRSTHALYVRQVVRQFLNEAHRRHGQITLDVPGQDPVTDLALSIICNTAP
                     WTYLGNRPMYASPKASFDTALDVLGLKRLSTPAVALYGTQLLTSSPEKGPRGKHAVSRH
                     DLTDFTLHSKVPLPFQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(20535..20548)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.67"
                     /tool="antismash"
     misc_feature    complement(20598..20607)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20769..20784)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20772..20783
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
ORIGIN
        1 cgccgtccga gaccgagcag ctcctccacg aggcggcact gcgcggcgat gcccgggccc
       61 agctggcggc gctcgccggg gccgagctgt acatcccggc cccgcgcgcc gaggtggacg
      121 cgaagccgga caccatcacc tggcgcgcgc accacgaccc ggccggcttc gtctgccgac
      181 cggtgctcac ccgggggatg ctgccggcct ggcatccgga ctgggtcttc cacggggtca
      241 cgctgcgctg ggccgccgag ttcggctggc gcgacccgaa cgtgctcctc ggcgtgaacg
      301 tgggaacgcc cgggcagttg ctgctgccca ccggcccgat ggacctggcg ctgtggcagc
      361 gcgcgtacgc ggagaacgac cgccttccgg agaaccggct gctcgcgctg cgccacggcg
      421 cgctgcacgg gccgctggcg tacgggctgg cctgcggggc acatctggcg atcgggaacg
      481 cggtgccgtg gaacgaggtc ggcacggtct accgcgagta caccaccgag cgcgatctgc
      541 tccgcgagtc ctggggcatc accgaccacg cggagtggcg caagcagctg gacgccttgc
      601 tggaggcccg caacagcccg ccggaaccgg acttcgtgct gcgcacccgc gaccaactcg
      661 cttcggcgct gggcgagttg ccctcggccg acctgtggcg ggagaccgcg gcgggccacg
      721 cccaggacct gggggcggac tccggcacgg tgaagggcat cgaggagctg gtgcgccgga
      781 tcatgcgcta cgaggcccgg ttccgcgcgg acgggctgct gccgccggac ggccgggtcc
      841 gtacgacggt ggcgtacgac tacgggcggg cggtgaacct ggcgcgctgg gggctggcgg
      901 cgcgctactg cgccccggcc gacgcggagc aggcgatcgt ctacgccggg gcgctgagca
      961 agtcggccca ccgctcctgg gaggagttct cggcgggcta ctcgctgggg cgggtgctgc
     1021 ggttcgacga ggaggagtac gggccgttct acgagaagaa cgtcctcgcc caccgtctgc
     1081 tggcggagag cgagggcagt ccgtggcgcc atatcccgtg gcgctgagcg cggcgtgacc
     1141 cgcgggcccc gggcggtccg cgccggcctg ccgcaggtca gccggaggtc agccgcgggt
     1201 cagccgcccg gcagcaggtg tcggtagctg tcggggttct ccaccaggaa ctgcgcgaag
     1261 ctcttggccg ggtgcccggt gagcgtgggc accgcgtcgg agacggcggc cagctccccg
     1321 cccgcgatgg cctcgtacga ggtgacccag ccggccacct cccagtcctc ggccccgtag
     1381 ccggcccggg aggcgtaggc ctcctcgcgg gtctcgggga cgtagacgac gggacgcccg
     1441 gtgacccggc tcagttcatc ggccgcctcg gcgagggtga acgcctcggg tccggtgagg
     1501 tcgtagaccc ggtcgtcgtg gtccgtgccc tcgtccagca gcacggccgc cgccgcgtcg
     1561 gcgatgtcct cgtgggcgac ggccgccacc cgtccgtcgc cgcccggtcc gcgcagcacc
     1621 ccgtcggtcc cggtcatcgc gggcagcccc gccagatacc agttgtcccg caggaacgtg
     1681 tggcggatct cggccgtacg gatgtgggcc tcggtgtccc agtgatcgcg ggcgaaggtg
     1741 aacgtggcgt cgggcgcggc cccctggaag gacacgtaca cgatccgttc cacgcccacc
     1801 gccacggcgg cgtcgatcgc cgtggtgtgc tcgcggaccc ggtaggggct ttcgtgggcg
     1861 gagaccagga acagggtgtg ggccccgtcg agggccctgc gcatggcctc cgcgtcgccg
     1921 tagcgggcgg cgggcgcgtg gtcggcgccg ggcaggtcgg gcagccgggc ggggtcgcgg
     1981 ccgaggagcc gcacgggtac gccggtccgg gccagtcgtc gggcgacccg gccgccgacg
     2041 gctccggtcg ctccggtcac cgcgatgagg gggccgatca ctggggttcg tcttcctctc
     2101 gtcgtcctcc gtcccagggc cgcacctcca cgaccgcgcc caccgggagc ggtccgtaca
     2161 ggtgcgggaa ctcctcgccg ccgggcttca tcgcctcgta ccggacgggg tcggcgaggc
     2221 gggcggggtc gacgaccagg accacgaggt cccggtcgtc gtccccgtac agcatccggg
     2281 ccacaccggg gagttggtgg ggcagcgaga ggtggatgaa gccctcctcc tggagggtgc
     2341 ggccgcgggt ggacatctcg tacgtccctg tcccgcgggc cgcctcccac agaggtgctt
     2401 cggcgaggtg cagcagcggc tcggtcatcg aaccacgcta acggtcggtg ctcagcgccc
     2461 gctagaaggt gcggcgacga gccctgcgcg tggccacgag cacggtgcca cctgcggcga
     2521 ccagcgctgc cgcgatggat ccgatgatcc attcgccgcc ccgggagccg gtgtcgggca
     2581 gctcacccgg gtggctcggc gagtgcgtgg ggtgcggcgt gtgaccggtg ggcgtggggg
     2641 tgggctcggt gggagtcgcc gtgggctcgg tcggggtggg agtgggttct gtgggtgtcn
     2701 nnnnnnnnnn nnnnnnnnnn nnnnggcgtc ggctccgtgg gcgtcggcgt cggctccggc
     2761 gtgcaggtcg gcaggtcgcc gtcgaagggg tacgcgtgga tctcctggcc gcccgacgtg
     2821 cccgaagagg tgtgggtgag cgaacccgcc gtgtagaagc ggccgttggt gccgctcatg
     2881 ctgagcacgg tggtgctcgt cggctggccc accagcacgc tgccctcgaa ctgggccggg
     2941 ccggtcatgg acaggtcggt ggcgtccggg aagttccaca gcaggttctc gcggaggccc
     3001 tcgttgggga acgagcccat gaacgtggcg acgctgcggg tggatccgta gacgttgacc
     3061 aggacggtcg ccccctcggg gatgccgttg aacacgaacc ccgtattgcc gcccgcctcc
     3121 gactccaggt ccgcgtccac gtcgaagatc tggatcgcgg acgagccgtc accggtgaag
     3181 gtcatgaggt caccggtctt cacccacgtg cccgtcgcct cgcggtgctc gtcgccgtcg
     3241 tacgcgtagc agtggctcgc ctcggtgagc tgcgggcgca gctccgtgta cggggcggcc
     3301 gcgtcctcgt cgaagcgcgg ggcggtggcg ggttccaccg tgccggtgag gtcacccgcg
     3361 tacgcgacgc ggccggagtg cgtgccctcc tcggcgagca gacgctcgcc ctcggcgatg
     3421 gtcacgtccc cgcccgccgt caggtagtcg gagccgtccg gcggcggcac ccgcgaaccg
     3481 acgcccgcga tgccgacgtt gtagatctgc gagaccccgt cccgcttgtc catgtcgaac
     3541 cggccgagag tgacgacctt cccctccgcc tcggccgccg cctcccggac caggaagtca
     3601 ccgccgacgt agacgttgat attgctgtcg aagtactcga ccgggccgtt gttggggtcg
     3661 ttccagctgg gcgggcagga gctgccgagg cagggtccca gtccgcccgg cagcggatcg
     3721 gcgcccgcgg ccggcgccag cacgcccacc atcgccgcgg ccgtggccac tgtcactgct
     3781 gcccggattg cgttgccgcg cctgcgcgcc ttctgttcca tgccgcgcaa tatgcatggt
     3841 caacacttag tcattttgta tgacacgccg atcttgctcc tttgtgtaga cctataggag
     3901 gtttcttcgc cgcgacacgc gcacggaggc ggcccgtcag agagccagca gcttcgcctc
     3961 cagcaggggg tcgaggccga cgaccgggcg gtcggggcgc tggggcgcca cgcccccgag
     4021 gctgcgcagc caggcccagg tgtccgcgac ggtctcctcg gccgggcggc agcgcagccc
     4081 cgcggcgtac gccctggtgt ggtcgccccg gtgcagcgtg tcgtacagct cgcccggcgg
     4141 cagccagatc ggcaggtcgc tccagggttc ggccccggca gccagcagga cctccggatc
     4201 ggtccagcgc agctcggcgt cggccccggt gacgcgcacg caggcctcca acagctcgcc
     4261 catggtcgtg tggccggggc ggctgacggt gttgtacgcg ccgtgcagcc cgcccgccgc
     4321 cgcgcccagg atccagtccg ccaggtcccg ggcgtcgatg tactggagtt ccgtcccggg
     4381 ccggccaggg gcgatcaccg ggccgccccg cgcgatccgc gtcagccacc agggcagccg
     4441 gccgatgttc tcccacgggc cgatgatcag tccggccctc gccagcaggg cccggtcgcc
     4501 gaaggcgtcg agggcggcca gctcgccgcc gcgcttggcc cggtcgtacg gcacgtccgc
     4561 gccgtcgtcg ggcgacgctc cggccaccag cgggccgttc tcgtcgagtc ccggggcggc
     4621 cgggtaggcg tacaccgagc ggctggagac gtaggcgaag tgcccggccc ggccggacag
     4681 cagacgggcg gcgtcgcgga cggcggcggg cgcgccgctc caggtgtcga cgaccagatc
     4741 ccagtcctgc ccgctctccg ccagggccgc gagtccgtac gggccctcgg tccggtcccc
     4801 ggtcagcgcg ctcacgccgg gcgggggcgc gtgacggccc cggtggaaca ccgtgacgtc
     4861 ccagccccgc tccagcgcgg cgtcggtgac ggcccgtccg acgaactccg taccgcccag
     4921 catcagaagc ctcatggttc gactctgccc accggaaggc ggcgggtgaa cccgtccacg
     4981 ctgtcagcag aacgggggac ccgacgtcgc gggggcggag gactccgcgg cgcgagcggg
     5041 acggcggagg gtcagggcgt gcgggccagc ggggagcggt ggcgcagcag ccactcgtgg
     5101 tagccgctcg cccgtcgcgc cgcgtcccgg taggcgtcct ccaactgcgc gtacaccacc
     5161 gcgatgtccg tcccgggccg ggagaccagg agcagccgta ccgcgagcgg gtcgcccagc
     5221 agcgggcgga tcaccatgtc gtcgcgcggg cccgacgtcg gctggcaggg ggcgacggcc
     5281 tcgccgagca cgacgaggga ggcggcggtg aggtagtcgc cgtgcaggac cggagggttc
     5341 aggccggcgg cgccgagcac ccggcgcacc ccgtcccact cgccgtccac cgtcggatcg
     5401 accatccacg ggtcgcccgc caggtccccg agctccacca cgcggcggcg ggcggcgggg
     5461 tggtcgcggg agagcgagat gaactgcggc tcccggtcca cgagtacacg ctgctccagg
     5521 cgctccggca cggcgagcgg ggagccctcc acctcgtgca cgaaggcgac gtccaggcgg
     5581 ccctcctcga ccgagcgcag cagcgcgtgg gcggagacgt cgacccgcag cgagatgtcg
     5641 gtgccgggca gggcgaccct cagccggcgc agccagccgc cgatgacccg gctcgcggtg
     5701 gagccgatac gcagccggga tccgcgcggc cgggcggcct cggcctccgc cagcgcctcg
     5761 gcgaccaggt cgctcatgcc gtccacgagg ggccgggccc ggctcaggac ggcccgcccc
     5821 agggaggtcg gccggcagcc ggtccgttcg cggcggaaca gctcggcgcc gagcacgttc
     5881 tcgatccgcc gcagctgggt ggtcagggag ggctggctca cgccgaggcg tcgggccgcc
     5941 tgatgcagac tgcccgcgtc ggcgatggcg cacagcgccc tgaggtgtct cacctccagc
     6001 tccatgcagc ggagactatg accgccgcac gccgcgcacc agacgtcgca accccatcaa
     6061 acggcggcaa ttcagggagt gttgggcccc ggtacatgtg acgatgccgt gcgcgtgagg
     6121 tgagcgcggc atgcccttgg gcggctgacc tgcgcgaaca gggggccggg gcggcgatag
     6181 ggcggcgcta tcaccgttcg gcatcatccc cggcgactgt gtgctgcccc acactcttcc
     6241 ccgtaccgcc ccacgccttg tccgcccagc ggacaccccc acggcgcggg ttcgatcgga
     6301 caggtaggag aaacccccca tgagacacct caggactgcc gtcgccaccg ccgccgccgg
     6361 gctcggtctc gtcgccgcgc tcggtaccgc acccgtcgtc gccgccgccc cggcccctgc
     6421 cgccccctcc tccaccacca tcgccgcgta caacggctcg ggcgagaacg ccgcggccaa
     6481 ccgcgccttc ctcgacgccg tcatgaagtc cgtcgccgag aagcgcgccg ccaacccggg
     6541 catcaaggcc gtcacggtca cctacaacgc gtcgagcgcg ccgtccttcc gcggcgagat
     6601 agccaacagc acgcagatct ggaacagctc ggtctccaac gtccggctgc aggaaggctc
     6661 caacgcggac ttcacctacc gcgagggcaa cgacccccgg ggctcctacg cgagcaccga
     6721 cgggcacggt cgcgggtaca tcttcctgga ctaccgccag aaccagcagt acgactcgac
     6781 ccgcgtcacc acgcacgaga ccgggcacgt cctcggcctg ccggacacct actccggtcc
     6841 gtgcagccag ttgatgtccg gcggcggtcc cggcccgtcc tgcaccaacg cctacccgga
     6901 cgccaacgag cgggcccggg tgaaccagct gtggcagaac ggcctggccg cgctcgcccg
     6961 ctccgcttcc tgacaccggg acacaccggc ggtcaggcgg aggacggccg gtcccgtgtc
     7021 ccgggaccgg ccggaacccc ccacacgaca gaggaccgtt ccgctcgcgg aacggtcctc
     7081 tgcgcggtgc gtgcccgggg tgccggtcag gcgtcgagct cgctgcggac gaggaccagc
     7141 agctcgtcct cggtcatccc gaggtcccgg gcgtccgcga cggcttcacg gacccgctcc
     7201 agcagccggg cccgctgcgg cgacgcgtcg gcggtgatcg ccgcgccccg gccgcggcgc
     7261 agctcgatga gcccttcctc gcgcagccgt tggtagccgc gcagcaccgt gtggacgttc
     7321 acgccgaggg attcggcgag gacccgggcg gcgggcagcc gctcgcccgg gaccaccgca
     7381 ccgtcggcga ccgcacgccg gaccgaggcg gcgatctggt cgccgagcgg gacggtggag
     7441 gtcggatcga cccggaagag catggtcagc gccccgtccg ctgccggtcg agcagcgtgt
     7501 tgaggagggc cgcgccggtg gccgagtcgt cgacggtgac ggcgaactcg cgaccgctcg
     7561 tcaggctgac gacgatggcc tcgcccgagc gggtgatgac accgctgcgc tcggggcgga
     7621 tgcggtagcc ccaaccgccg tactccgcga gtgcgttgac gcggcggctg tccgcccccg
     7681 ccatccgctc cagcggcacc cgcacccggg gccggggcag cagtccggag acggtgaggc
     7741 cccgccggtc cacggtgacg tgcgggcggc agaaggtggc cgccaccagg gcgaggagga
     7801 acagcggcac cccgacgaac cagttcacct ccagaccgac ggtgacaccg gccgccagga
     7861 acacgagcac ggcgatcggc gcccaccaca ccccgatccc gcgcgcccag ccggccactt
     7921 cgccgtcggc gagcgcgatc ctctcccggt tcgccggatc cgtgtcgcgg gggtcctcga
     7981 cggcggggac gagtcgggag cacagcaggc cgagggcccc ggcgaggacg cccgccccga
     8041 gggccacggc gatgtgccac agcgggaagc cgccgtccgg gccgctctcg ggagcgtcca
     8101 cgttgacgaa caggacggcg atcatcagat agccgaggaa cgccgcgacg gcgaagcctc
     8161 cgccgatgaa ccaccggtgg gcgcggccgt agaccttgcc gttggccgcg atgaaggccc
     8221 acagcgcgcc gagcacgagc agcgacgtga ccgtgtagag gaggtgggcg gtgatgccca
     8281 tgtagccgtt ggcggaaccg ccggcgtcga agtggacggc cagccgggcg ggcagacggt
     8341 ccttgacggt gacgtgaagg acgaggtcga cgaggagtgc gagcacaaag ggcagggctg
     8401 cgagcgttgc gcggccaagg ttcttacttg tcatggaaaa cctccgttgt tcgcatgcta
     8461 gtagaacaat gaggccgagg caacggcatg acgcgcgtcc gccccgtacc gggacgcggt
     8521 acggggcgga cgcgggtgat cctgttggcg gcgggcgatc ccggcggggc gggcgctccc
     8581 ggggtcgggt caggcgagtt ccagcgggaa ggctccgcgg tggccggtgc ccgcaccgtc
     8641 ggccgggcgc acctcgaact cgcggcagct ccagacctcc tggacgaacc cggacctccg
     8701 gtcccacaga tcccgtacgt cgttctcgcc cgccgagccc cggtaggcgt ccttggcccc
     8761 ccggaagcag gcgagaccgc cggagaggcc ccggccgggg gccgggaagt agtcggagaa
     8821 ggcgcaggcg acacaggtct ggatccggac gccgtcgggg aggatccgct ggacggtggc
     8881 cagggcggtg tcgaagtccc gctcggcacg ggccgattcg tacaccgcgc cgtccaggtg
     8941 gagggcgaga tggagatccg gatcgacccg ccgcagggag agcaggcaac tgagcgtggc
     9001 gtggcggagc gtgcccgcga cgaggacggg cagcggcagg tcccactcca gtacgcagtc
     9061 ggtgagcgcg ccgtccgcga gagcgaacat cccgctctcc ggcggcgggc cggcgaccgg
     9121 ccccaggccg tcgaaactct cgccctcgaa gtcgacccct ctgatccgga tccggagctg
     9181 ccgcccgtcc gtggtgagaa cgacggcgtc ggaacccttg gtgtcccggt accagccggc
     9241 ccacgactca tctgtcatga gcagggactg tagcccctgc cccggacggc ttgcgtacca
     9301 ccctccgcga gaactcaacc cgcttggggc tcccgccaca tggggtacat cggcgggccg
     9361 tccggcagct cgacggcgcg gcccggaagg cggaatccga gccgctcgta cagcacccgg
     9421 ctccgggcgc tgctcgcctc cagataggcc ggcaggccct cccggtcgca gcgctccagc
     9481 tccgctccga tcagctccgc gccgataccc tccccctgac ggtcgggggt gacgccgatc
     9541 atcagcagat aggcgtgcgc gcggtcgtgc gggtgaacgg ccccggtgag cctgcccacc
     9601 agttcgcagc gctcgttgtc ggggtcggcg gtccggcgca tcagggcggg cgtcgggtcc
     9661 tccccctcgg gggccccggc gggcaccggc agccagaggg ccaccgcggc cccgtcctcg
     9721 gcgatgtcga tacgcccctc ggcgagggcg acgtcgacga agacgccgag gaacctgccg
     9781 tggaccgcgc gccggtgcgc ctcgtcgggg aacacccagc agctgaccgg gtcgtggtgg
     9841 aacgcctttt ccatgaccgc gacgaccagc tcccggtcgt gctgctccgc ccgttgaatc
     9901 cgtatgccca tgaccggctg ccgcccttcc gtgctgtttt cgctcaacca acctccggaa
     9961 tcctagagtt gatgggtcgg tgccggtcac gcgaggtggt tcagctggtc ctgcgggtga
    10021 cgaattcggc cagcgccagc aggtctccgg ccgcacccgg gtcggggacc gcccgggaga
    10081 ggtggtggac cgcgcgggcc atccggtcgg ccgcgcagac ctgggcccag tcccggccgc
    10141 cggcccggtc caccgcgtcg gcggcccggc tcacctcgcc ggaggtggtc atgggccccc
    10201 ggtagagcgc ggcgagctcg gcggcggccg gggtgcccga ggtgagggcg gcgacgacgg
    10261 gcagggactt cttgtgggcg gacaggtcgg ccccgacggg cttgccggtg cggtccgggt
    10321 cgccccagat gccgatcagg tcgtcgatga gctggaacga gaggccggcc tcccgcccga
    10381 acccgtccat cgcgcggacc gcccggtcct ccgccccggc gtagagcgcc ccgagggcgc
    10441 aggcgcagcc gagcagcgcg ccggtcttgg cggtggccat ggcgaggcat tcgtcgagcg
    10501 tgacctcgtc ggggccgcgc tcctcgaagg cgcagtccgc ctgctggccc gcgcacagct
    10561 cgatgatgca ggaggagagg cgggcgacgg cgggcgcggc ggccgggtgg gcgtcctcgg
    10621 ccagcagccg ttgggccagg gcgagcatgg cgtcgccggt gatgacggcg tccgggatgc
    10681 cgaagaccgc ccaggcggtg ggccggtgtc tccgggtggt gtcctcgtcg atgacgtcgt
    10741 cgtggagcag ggtgaagttg tgggcgagtt cgacggccac ggcggccctg acggcgcgtt
    10801 ccggatcgcc gcccagcgca cgggcggcgg ccagcacgag ggcgggcctg atggccttgc
    10861 ccgcctggcc ggtggcgggg gttccgtcgg cgttctccca gccgaagtgg tacatcgcga
    10921 cgcggcgtat gccgccgggc agcgactcca cggccgatcg cagatgcggg tcgacgacgg
    10981 cacgggtgcg ctccaggagc gcggccgcct cgtgcccttc cgtcgctgcg tccgtactgg
    11041 tcatggtcac ggtcactccc tggggcgagg cgatgggtac ggggtgcggg gcccgggcga
    11101 ctcctgccgc ccgggccccc ggggtgaagc cggggtcagt gccggcgacc gacctcgacg
    11161 ttctccagca ccccgagggc gtccggcacc aggacggcgg cggagtagta cgccgtcacg
    11221 aggtaggaga tgatcgcctt ctcgtcgatg cccatgaagc ggaccgagag gctcggctcg
    11281 atctcgtcgg ggatgcccgt ctggtggagg ccgatgacgc cctgctccgc ctcgccggtc
    11341 ctcatgcaga tgatggaggt ggtgcgggcg tcggagacgg ggatcttgtc ggacgggaag
    11401 atcggcaccc cccgccagga gggcacgtgg tggccgccga tgtcgatgct ctccgggacg
    11461 agtccgcgcc ggctgcactc gcggccgaag gcggcgatgg ccttcgggtg ggcgaggaag
    11521 agcttggatc cgcggcggcg cgagagcagc tcgtccatgt cgtccgggcc gggcaccccg
    11581 tcgtgcggct ggagccgctg cccgtagtcg cagttgttga gcagcccgaa ctccctgttg
    11641 ttgatcagct cgtgctcctg gcgctcgcgc agcgcctcga ccgtgagccg caactgctgc
    11701 tcggtctggt tcatcggctg gttgtagagg tcggcgaccc tgctgtgcac cttcagcacc
    11761 gtctgggcga cgctcagttc gtactcgcgc ggcgccgctt cgtagtcgac gaaggtgtgc
    11821 gggacgaccg cctcccccac atggccggcg gagaggtcga tcgccgcctc gccgtagtgg
    11881 ttggtccgct gtcgcgggat ggagagcagc ccggcgagat ggtcctgcag cgacgcggcg
    11941 cgctccgcga ggttgtacac gtcggcgcgg ctcagggtga gcagtgtgca cgaggtgacg
    12001 gcgcgggcgg tgtactccca gacggcgtcg ccgtcgatca ggctccggtc gccgaagtac
    12061 gcgccgtcgg cgaggactcc gagctccgtc tcgtccccgt aggggcccga tccgatcttc
    12121 gccaccttgc cgtgcgccag caggaagacc cggtccgccg cttcccccga ggcggcgagc
    12181 acctcccccg cggccacgtc ccgctgctcg cacctgcggg ccagctcggc gagcacctcc
    12241 tcgtccccga actcccgcag ggcgggcagc tcccccagct ccgcggggat cacggacacc
    12301 cggcccccgg tctggacgaa ggtcacccgg ccgtcaccga ccgcatagct gagccgacgg
    12361 ttcacccggt acgtaccgcc ctgtacctgc acccacggca gcatcttcag cagccaccgc
    12421 gaggtgatct cctgcatctg cggcgcggat ttggtggtcg tcgcgaggtt ccgcgcagcc
    12481 gccgtcccca gactctgctg cggcggcgcc tgcgtgtcgc gaacctcttc accaacggac
    12541 atctgacgtc ctttcgatct tgggctgacc tgcgtgcaaa agcctttcag caggaggacc
    12601 gggtcgccat tacacaaaag agtgcgacta atccgccttc ggtcggggca cgttgcccct
    12661 cgtcgcccgg cggaccacat aacttgcatc tcttatgcaa cttatctacg gttgacccat
    12721 gcggttgacg agattcaccg acgtggcact ccgcgtcctc atgcgactgg cggtcgccga
    12781 ggaccgggaa ccgccgacca cccgcgaggt ggcggccacc atgcgggtcc cgtacacgca
    12841 cacagcgaag gtcgtcgcca ggcttcagca cctcggcctc ctcgacgccc gtcgcggccg
    12901 gggcggcggg ctcaccctga ccccggccgg ccgctccgcg tcgatcggct cgctggtgcg
    12961 ggagctggag gggccggagg aggtcgtcga gtgcgagggg gacaccccct gcccgctccg
    13021 ctccgcctgc cggctgcggg gcgccctgcg caaggcccag gacgccttct acgccacgct
    13081 ggacccgatc accgtcgccg acctcgtcgc ctcccccacc ggcccgctgc tgctgggcat
    13141 cggcagccgc cctccacccg actgaacccc gccccggccg cgcgaacgaa cccacgcgcc
    13201 gccggggccg ccccctgcca ataaatatgc atctcacatt ccaataagga gctccgtcat
    13261 gctctccgac cggtccaccg ccactgtccg cgccaccctt cccgccgtcg gcgcggccat
    13321 cggggacatc gccgacctct tctacgagaa gctcttcgcc gcccaccccg agctgctgcg
    13381 ggacctgttc aaccggggca accaggcctc cggcgaccag cggcgggcgc tcgcgggctc
    13441 catcgccgcc ttcgcgaccc agctggtcga gcggcccggc acccggcccg acgtgatgct
    13501 ggaccggatc gcccacaaac acgcctcgct cggggtgacc ccggcgcagt acgaggtggt
    13561 gcacacccat ctgttcgcgg ccatcgccga ggtcctgggc gacgcggtca ccccggaggt
    13621 cgccgccgcc tgggacgagg tctactggct gatggcgggc tccctgacag ccgtcgagga
    13681 gcgcctctac gcgcagcagg gcgtcctggc gggcgatgtg tggcacacct gggaggtgac
    13741 cgcccgggtg gaggagaccg aggacgtcgc caccttcctg ctgcgccccg ccgacgacac
    13801 gcccccgccc gccttccggc ccggccagta cgtctccgtc caggtcgaac tcccggacgg
    13861 cgcccgccag atacgccagt acagcctctc cagcgccccc ggctcccggc tgcggtcgat
    13921 caccgtgaag cgcgtgcgcg gccagggcac gcccgacggc gaggtctccc ggcacctgca
    13981 cgagcacacc cgcgtcggcg acctgctgcg cgtctccgtc ccctacgggg acctggtgct
    14041 cgaccacctg gacgcgcccc tgctgctggc ctcggcgggc atcggctgca cccccatgct
    14101 gtcgatgctg gaacacctcg tccaggaggg ccacagcggc ccggtcaccg tcgtgcacgg
    14161 cgaccgttcg ccggccgacc acgccctgcg caccgaccac gtccggctga cggagaagct
    14221 cccggacgcc gaggcgcact tctggtacga gaccccggag gccgggcagc cggcgaaccg
    14281 caccggcctc gtcgacctgg aaggcatcac cgtacgcccg gggacgcacg cctatctgtg
    14341 cggcccgctc cccttcatgc gggctgtcag ggcccagttg ctggaggcgg gggtccggcc
    14401 ggccgacgtc cactacgagg tgttcggccc ggacctctgg ctggcctctt cctgaaacac
    14461 cggagaggcg acaatgggcg ggtgaacagc ccgccccgcc tcgacgccct cctgcggccc
    14521 cgggtgccct cgccgctgcg ggaggtccac gacgaacgct tcgcgcgcca cggtgtgcgg
    14581 ctgttcctca agcgggacga tctgatccat cccgacctgc cgggcaacaa gtggcgcaag
    14641 ctcgccctca acctggaggc cgccgccggg cgcaccgtgc tgacgttcgg cggcgcgtac
    14701 tccaaccacc tccgggcgac cgcggcggcc gggcggctgc tgggttttcc caccgtcggc
    14761 gtggtccgcg gcgacgagct ggcgcaccgg ccgctcaacc cctcgctcgc ccgctgcgcg
    14821 gccgacggca tgcgcctgca tttcgtggac cgcacgacgt accgggcgaa ggcctcgccc
    14881 gaggtcctgg aggggctgct gagcctgttc ggggaggtgg aggtcatccc ggagggcggc
    14941 agcaacgcgc tggccgcaga gggctgtacg gcactgggcc gcgaactggc cggagcgtgc
    15001 gacgtggcgg ccgtggcctg cgggaccggc ggcaccctgg cggggctcgc cgccggcctg
    15061 ggccccgggc agcgggccct gggcatcccg gtcctgcgcg gcggcttcct cgggcgggag
    15121 gtggagcggc tccagcgcga ggcgttcggc ggcccgtccg ggaactggtc gctggacgag
    15181 cgcttcgcct tcggcggcta cgcccgctcc accccggagc tggaggcctt cgccgcggac
    15241 ttcgaggacc ggcacggcct gcccgtggaa cgcgtgtacg tcgccaagct gctgttcgcg
    15301 ctgaccgcgc tgaccgcgga gggggcgttc gcgccgggcg cccgggtgag cgccgtgatc
    15361 accggcaccc ccgacgcacc gccccctcag gacgcgtccg tctcccggta ggccgccgcc
    15421 tcctccagat ccagccggcg cagcagggtg cgcatcatct cgtcgtcgat ccgccgctcg
    15481 tcccggagcc ggacgaagac ctcgcgctcg gcctcgatca tctccctcga cagccgccgg
    15541 taggtgtcgt ccgccgactc cccggtcacc gggtcggcgg cgcccagccg ctcccacacg
    15601 gagttgcggc ggcgctccag cacactgcgc agccggtccg ccaacggtgg cggcagactg
    15661 ctgtgcgggt cggcgagcag ctggtccagg cgggcctcgg ccgcctcgga cgcctcgttc
    15721 tgggcctgcg cctcgacgag cgtgacggtc tgcgggtcgg ggcccggcag cttcagtacg
    15781 cgcacgagga cgggcagggt gaggccctgg atcaccaggg tcccgatgac ggtggtgaag
    15841 gtcaggaaca gcaccaggct gcgggccggg aagggttcgc cgtcgagcat gaccaacgga
    15901 atggagaacg cgacggcgag cgagacgacc ccgcgcatcc cggcccagcc cacgatcagc
    15961 ggcgcggtcc agtcggtgcc cggttcgcgt tcccggactc ggcgcgagag ccaccggggc
    16021 agataggtgg ccgggtagac ccagacgaag cggaccacga cgacgaccag gaacacgatg
    16081 gccgcgtaac cgagcgcctc ccacacgccg aacgagccga gccccttcag gacgaacggc
    16141 agctggagcc cgatcagggc gaacaccgcg gactccagga cgaaggccac catcttccag
    16201 acggccgcct cctggagtcg ggtggcgaag tcgacctgcc aggagcggtg gcccaggtag
    16261 agggcgacga cgaccacggc gagcaccccg gaggcgtgca cccgttcggc cgccgcgtac
    16321 gccacgaagg ggatcaggag ggagagggtg ttctggagga gggcttcctt caggtgcgtg
    16381 cgcagccagt ggagcggcac catcagcagc aggccgacgc cgaccccgcc gaccgcggcc
    16441 agcaggaact cgccgatccc cgcgccccag ctcatcccct cccccaccgc ggcggccagc
    16501 gccaccttga aggcggtgat cgccgtggcg tcgttcacca gggactcgcc ctggaggatc
    16561 gtggtcaccc gggagggcag cccgacccgg cgggcgatcg cggcggccgt cacggcgtcc
    16621 ggcggggcga tgaccgcccc caggaccagc gcggcggtca gcggcagatc cgggatgatc
    16681 aggtgggcca gccagcccac ggcgacggtc gcgaagaggg tgtaccccac ggagagcagg
    16741 gcgaccggcc ggacgttggc ccgcagatcc agataggagc tgtccagggc cgccgtgtgg
    16801 agcagcggcg gaagcagcag cgggagcacc acgtgcgcgt ccaggtggta cgtcgggacg
    16861 cccggcagat agccggccac gagccccacg gccaccagga cgagcggggc gggcaccggt
    16921 gtgcggcggg ccgcgccggc gaccgccgca ctgaccgcga ccagggcaat cagcggcagc
    16981 gcgtccatcc caccgtcctc ggatccgtcg taacctgccc atcatgagcg agtgcgcgca
    17041 cgtagccgaa ctgccacgcc ccgagccggc gccgctcggt gagacgtgcc ccgagtgcct
    17101 ggaggcgggc agccaccccg tgcagctgcg gctctgcctg acctgcgggc acgtcggctg
    17161 ctgcgattcg tcgccgctgc ggcacgccac cggacacttc cgggcgaccg gtcaccccgt
    17221 gatgcggagc ttcgaggcgg gcgagagctg gcgctggtgc ttcgaggacg gttcgatcgt
    17281 ctgacgcctg ggtacgtcaa tgcggcgctg gttcttcgca attggacgcc gcagacccct
    17341 agccactgtg cgtacgcatg ggcttaccat gagtgacggt cggggtatgg ggtccgtacg
    17401 acacggcatc atggatccga taacgtcgcc gagccgaaga accgtcgacg gaccgcatgg
    17461 ctccgggcca cccttcccgg agcctcgaaa gagtttgtgc caccttggag gtgagggtgt
    17521 cccagatcgc aggcgagccc gggaatcagg acttcgtaga agtccgactg ccggctgcgg
    17581 gtgcctacct gtcggtgctg cgaacggcca cggccggtct cgcagcgcgt ttggacttca
    17641 ctctcgacga gatcgaggat cttcgtatcg cggtcgacga ggcctgcgcg atcctgcttc
    17701 agcaggccgt gccgggctcc gtcctcagct gcgtgttccg tctcgtcgac gactccctcg
    17761 aagtgacggt gtcggcgccc accacggacg gccgcgcgcc cgagcgcgac accttcgcct
    17821 ggaccgtgct ctccgcactg gccggcaagg tcgactccac ggtcgccgat gaccgtacgg
    17881 tcagcatcag cctctacaaa cagcgcggcg cgggccccgg gccggcgtga gcgacgggaa
    17941 cggggacggt cctgtgcggg acgagacgat ccgatccggg gtggtgcggc cggcaggcat
    18001 cccggagcaa caggcccggc cgcatccggt ggacggagcg gacgggcccg agagcatcga
    18061 cgtcgcggtg gagcagcagt cgcaggcagg gcgggcgggc cagatgagcg agcacgggca
    18121 ccacgatcca catgaccgca gcggggcccg ggccctgttc ttcgagctgc gggagctgcc
    18181 cgacggttcg gcggagaagg ccgagctgcg caacaggctg gtgcggatgc acctgccgct
    18241 ggtggagcac ctggcccgcc gcttccgcaa ccgcggggag ccgttggacg acctgaccca
    18301 ggtggccacg atcgggctga tcaagtccgt ggaccggttc gacccggacc ggggcgtgga
    18361 gttctcgacg tacgccaccc ccacggtggt cggcgagatc aagcgccact tccgggacaa
    18421 gggctgggcg gtgcgggtgc cgcgccgcct ccaggaactg cggctgtcgc tgaccacggc
    18481 gaccgcggag ctctcccagc agcacggccg ctcgccgacg gtgcacgagc tggccgagcg
    18541 gctgggcatc tccgaggagg aggtgctgga gggcctggag tcggccaatg cctacagcac
    18601 gctctcgctg gacgtgccgg acaccgacga cgagtcgccg gcggtcgcgg acacgctggg
    18661 ctcggaggac gaggcgctgg agggcgtgga gtaccgggag tcgctcaagc cgctcctgga
    18721 ggatctgccg ccgcgcgaga agcgcattct gctgctgcgc ttcttcggga acatgaccca
    18781 gtcgcagatc gcccaggagg tcggcatctc gcagatgcac gtctcccggc tgctggcccg
    18841 caccctggct cagctgcgcg agcggctgct cgtcgaggag tagacaggaa gggcgtccgc
    18901 cggttcgggg ccgcccggca gcctctcagg cctcgggggt cgccctgggg ccccggcgga
    18961 tgcccaggtc ctgggtggtg gccggcttga ggacgagcac gaggccggtg acggccacca
    19021 ccgccagcgc gatcccggtg gggatcagcg caccctgcga gcgcagcagc gtccaggcca
    19081 ccggcagcgc catgatctgc gtgatcagcg cgggcccccg gctccagctg cgcagcagca
    19141 gcagtccgcg ggcggcgatc agcgggatcg cgccgagcgc gaccagcgtg atgccgaccg
    19201 tctccgcctg ctgcgtgctc tccagcttcc cgagcagccc catgaccagc atgtagaccc
    19261 cgccgagggc gagcgccagg ccttcgaggg cgttgacccc ggcgaggacg gtgatcctgg
    19321 tcgggcgctc cgcggcggag ggcgacggcg tggagggggt cgcttgagta ctcacgcctt
    19381 tcaggttggc atccccgggg cccggaagtg aagccggggt gcgcgggagc ctcccccgtt
    19441 cggcggagga cgggggaggc catcacgctc cgtcaccggg gtcgagcgga gcgaaccggg
    19501 aggcactgtt ccgaccgccc ggtaggtagg ctggccgtca tgcgcgcact cctcgtggtc
    19561 aatccagctg ctaccaccac cagtgcccgc acccgcgacg tactgatcca cgcgctggcc
    19621 agcgagatga agctggaggc ggtgaccacc gagtaccggg ggcacgcgcg ggacctgggg
    19681 cggcgggccg cggacagcga cgacatcgat ctggtggtcg ccctcggcgg cgacggcacg
    19741 gtgaacgagg tcgtgaacgg gctgctgcac cggggcccgg acgtggacaa cctcccgaag
    19801 ctcgccgtgg tccccggcgg atccacgaat gtcttcgcgc gcgccctcgg gctgccgaac
    19861 gacgcggtgg aggcgaccgg cgcgatcctg gacgccctgg agaaccggac cgaacgcacg
    19921 gtcgggctcg gactggcggc cggcaccccc ggcaccgagg acgagtccgt tcccgaacgc
    19981 tggttcactt tctgcgccgg tctcggattc gacgccggag tcatcggccg ggtcgaacag
    20041 aaacgcgagc acgggaagcg ttcgactcat gccctgtatg tgcgccaggt ggtgcggcag
    20101 ttcctgaacg aggcccatcg cagacacggc cagatcacgc tcgacgtgcc cggccaggac
    20161 ccggtgaccg acctcgcgct ctccataatc tgcaacaccg ccccctggac ctacctgggc
    20221 aatcgcccga tgtacgcctc gccgaaggcc tccttcgaca cggctctgga cgtcctcgga
    20281 ctgaagcgtc tgtccacccc ggcggtggcc ctttacggca cccagctgct cacttcgagc
    20341 cccgagaagg ggccgcgcgg caagcacgcc gtttcacggc atgacctcac ggacttcacc
    20401 ttgcattcaa aggtcccact gcccttccag atggacggcg accacctggg actgcgcacg
    20461 agcgtgacgt tcacaggcgt acgccgtgca ctgcgtgtga ttgtgtgagt ggaagggccc
    20521 aaagtccttt aactcgaacg tttggactgg cccccacccc taagaagtgc ggctgtgacc
    20581 tagtcgacac cgaggaatca aaaaaaactt tccagaaggg gttgtatccg ccgccgaggt
    20641 ttgcgaatct ctacatggcg atcgggacgg cccgcaacac cggcctccac tgagagccag
    20701 aacccctcct caccacacag accacaccca gcacatctgg gagtcggccc gtcatctgcg
    20761 gggggattcg tgaaagcgtt cacattcaca agcaacaagc gtgtaatacc aaggagaggt
    20821 agcagccatg gactggcgtc acaacgccgt ttgtcgtgag gaagacccgg agcttttctt
    20881 ccccatcggc aacaccggtc ctgcgctgct gcagatcgag gaagccaagg ctgtctgccg
    20941 ccgctgcccc gtcatggagc agtgcctgca gtgggcgctc gagtccggcc aggactccgg
    21001 cgtctggggt ggcctcagcg aggacgagcg ccgcgcgatg aagc
//
