LOCUS       NZ_KZ195572            21326 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. CS057 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195572
VERSION     NZ_KZ195572.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS057
  ORGANISM  Streptomyces sp. CS057
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 265.32x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188345.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 02:40:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,152
            CDSs (total)                      :: 7,074
            Genes (coding)                    :: 6,991
            CDSs (with protein)               :: 6,991
            Genes (RNA)                       :: 78
            rRNAs                             :: 10, 6 (16S, 23S)
            complete rRNAs                    :: 10, 6 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 23 of 83
            Pseudo Genes (incomplete)         :: 71 of 83
            Pseudo Genes (internal stop)      :: 4 of 83
            Pseudo Genes (multiple problems)  :: 14 of 83
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:25:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1430611
            Orig. end                         :: 1451937
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195572.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..21326
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="12"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21326
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21326
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11326](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11326)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    69..80
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     misc_feature    211..225
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(326..970)
                     /locus_tag="B9W61_RS05805"
                     /old_locus_tag="B9W61_05805"
     CDS             complement(326..970)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764397.1"
                     /locus_tag="B9W61_RS05805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05805"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_007454866.1"
                     /transl_table=11
                     /translation="MDVLTENFSLYGKGFLGTVELTVYASALALVLGFLMASFRVAPVG
                     SFRVLGTVWVTVLRNTPLTLLFFAVLLGLPRFGLVLPFQVFAVLALGCYTSAFICEVLR
                     SGINTVPKGQGEAARSLGMNFGQTLSTVVLPQAFRSVIPPVGSTLIALAKNSAIAGAFS
                     VTELLGTYKTLNELGYSIIWSFIWIAVGYLIITLTISAVFNVMEKRWGVAR"
     gene            complement(987..1916)
                     /locus_tag="B9W61_RS05810"
                     /old_locus_tag="B9W61_05810"
     CDS             complement(987..1916)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965159.1"
                     /locus_tag="B9W61_RS05810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05810"
                     /product="glutamate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_087764403.1"
                     /transl_table=11
                     /translation="MLRTRNTRTGRAAALVAGLLLAALAAGCGKDGSPPVKGPKAEALP
                     VYQVDTGFELPDSRTWTKAKKRGYLVVGAKEDQPYLGEKDPASGIYSGFDIEIARMMSA
                     SLGFEPKTIRFRTIASANRETALQNGQIDYYVGTYTINDMRKKLVGFAGPYYMAGQGLL
                     VRTDENDIDGPQDLAGKTVCSAAGSTPYQRIAADYPKATLVAYDTYSICVDNLLTYQVD
                     AVTTDDAILLGFAAKAPDEMKVVGKPFSEEPYGIGVPRDDNALRNALNDALEANEKNGN
                     WKKAYEATLGLSGAPAPTPPPIDRYPAN"
     gene            complement(1928..2671)
                     /locus_tag="B9W61_RS05815"
                     /old_locus_tag="B9W61_05815"
     CDS             complement(1928..2671)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377699.1"
                     /locus_tag="B9W61_RS05815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05815"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_047179584.1"
                     /transl_table=11
                     /translation="MAVDPLIELRDVNKHFGELHVLQDINLTVGRGEVVVVIGPSGSGK
                     STLCRAINRLETIESGSIMIDGRPLPEEGKGLAQLRAEVGMVFQSFNLFAHKTVLDNVS
                     LAQLKVRKRKKDEADRRSRELLERVGLAAHADKFPAQLSGGQQQRVAIARALAMDPKAL
                     LFDEPTSALDPEMINEVLEVMQQLARDGMTMVVVTHEMGFARSAANRVVFMSDGCVVED
                     RTPEDFFTNPSSDRAKDFLSKILKH"
     misc_feature    2628..2637
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     gene            complement(2818..3258)
                     /locus_tag="B9W61_RS05820"
                     /old_locus_tag="B9W61_05820"
     CDS             complement(2818..3258)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128629.1"
                     /locus_tag="B9W61_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05820"
                     /product="DUF6278 family protein"
                     /protein_id="WP_047179583.1"
                     /transl_table=11
                     /translation="MNIPFLDNWRKRQGGTRSGALAAAVEADPDGVAELLAECELLRVR
                     AGQHGLELDDTPASLAALDQLPPRWRDDPEELPWLGNDAGLYLGTVIVRTVPGAAWDVW
                     PSGQPVVRLESGREIDVVAAGLDWAMAGSPELSQVYAESAEN"
     misc_feature    3234..3247
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.42"
                     /tool="antismash"
     misc_feature    complement(3243..3257)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.26"
                     /tool="antismash"
     gene            3368..4147
                     /locus_tag="B9W61_RS05825"
                     /old_locus_tag="B9W61_05825"
     CDS             3368..4147
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (16-180). E-value: 1.1e-12.
                     Score: 40.2. Matches aSDomain:
                     nrpspksdomains_B9W61_RS05825_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128628.1"
                     /locus_tag="B9W61_RS05825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05825"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_047179582.1"
                     /sec_met_domain="adh_short (E-value: 4.6e-30, bitscore:
                     103.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAHAYVSELFSLEGRVAVVTGGSSGIGRAITGALARAGARVVVV
                     ARREAELRATADELTAEGCRAAWVSADLGTAEGVRAGAEGAAQAFGEPDILVNCAGINL
                     RPPMAELGEDVWDTTMAVNLKAPFLLGQRFGPGMAERGYGRIIHVTSQQAHRAFVDSGA
                     YGVSKGGLESLARSQAEAWSAHGVTVNTLVPGFVLTPLNARLQSDPEKVASLAARTLVG
                     RNGLAEDFAGAAVFLAGRSSAYVTGQSVFVDGGFSVH"
     aSDomain        3416..3907
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W61_RS05825_PKS_KR.1"
                     /evalue="1.10E-12"
                     /label="B9W61_RS05825_PKS_KR.1"
                     /locus_tag="B9W61_RS05825"
                     /protein_end="180"
                     /protein_start="16"
                     /score="40.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGGSSGIGRAITGALARAGARVVVVARREAELRATADELTA
                     EGCRAAWVSADLGTAEGVRAGAEGAAQAFGEPDILVNCAGINLRPPMAELGEDVWDTTM
                     AVNLKAPFLLGQRFGPGMAERGYGRIIHVTSQQAHRAFVDSGAYGVSKGGLESLARSQA
                     E"
     CDS_motif       3422..3562
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9W61_RS05825_0001"
                     /evalue="3.70E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="B9W61_RS05825"
                     /protein_end="65"
                     /protein_start="18"
                     /score="19.6"
                     /tool="antismash"
                     /translation="VVTGGSSGIGRAITGALARAGARVVVVARREAELRATADELTAEG
                     CR"
     gene            complement(4181..4927)
                     /locus_tag="B9W61_RS05830"
                     /old_locus_tag="B9W61_05830"
     CDS             complement(4181..4927)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010064073.1"
                     /locus_tag="B9W61_RS05830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05830"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_087764404.1"
                     /transl_table=11
                     /translation="MTQPLPAAPSVRLDDLIEAIKKSNTDALGQLSGAVIAADHLGDVA
                     DHLIGHFVDQARRSGASWTDIGRSMGVTRQAAQKRFVPKKGDGASDLDPSQGFGRFTQR
                     ARNVVMAAHNEAQAARHAEIVPAHLVLGLLAEPESIAAGVLLGPEITPDALRAAAVAAL
                     PAAAEEVPELIPYDADSRKVLELTFREALRLGHNYVGTEHILLALLEFEGGSGVLSGLG
                     VEKDAVSAAVEAAVTEAAAALWQQKP"
     gene            complement(5020..5799)
                     /locus_tag="B9W61_RS05835"
                     /old_locus_tag="B9W61_05835"
     CDS             complement(5020..5799)
                     /EC_number="3.1.11.2"
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961423.1"
                     /locus_tag="B9W61_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05835"
                     /product="exodeoxyribonuclease III"
                     /protein_id="WP_073804022.1"
                     /transl_table=11
                     /translation="MRIATYNVNSITARLPRLLAWLESSGTDVLCIQETKCTAEQFPTA
                     ALAELGYESAVNATGRWNGVALLSRVGLSDVVTGLPDGPEYDGVQEPRAISATCGPLRL
                     WSVYVPNGREVEHEHYAYKLRWLEALRKAVAADAAKALPFAVLGDFNVAPTDEDVWDPA
                     LFAGATHVTPAERAALTALEAEGLSEVLPRPLKYDRAFTFWDYRELRFPKNKGMRIDLT
                     FGNAPFVAAVKDSYVDREERKGKGASDHAPVVVDLDL"
     gene            complement(5842..6495)
                     /locus_tag="B9W61_RS05840"
                     /old_locus_tag="B9W61_05840"
     CDS             complement(5842..6495)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965292.1"
                     /locus_tag="B9W61_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05840"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_087764405.1"
                     /transl_table=11
                     /translation="MNASSGALTLTKKTHSCVRIEKEGRVLVIDPGGFSEDDAALGADV
                     VLVTHEHPDHFNEARLRVGLEANPAAEIWTLRSVAEQLSAAFPGRVHTVGDGDAFSAAG
                     FDVTVHGELHAVIHPDIPRITNVGFLVDGSVFHPGDALTVPERSVDTLLLPVMAPWSKI
                     SEVIDYVREVKPRRAIDVHDALLTDLARPIYDNQIGALGGADHGRLAPGGTTEL"
     misc_feature    6481..6495
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.18"
                     /tool="antismash"
     gene            complement(6508..7797)
                     /locus_tag="B9W61_RS05845"
                     /old_locus_tag="B9W61_05845"
     CDS             complement(6508..7797)
                     /NRPS_PKS="Domain: Abhydrolase_1 (19-129). E-value:
                     5.6e-22. Score: 70.5. Matches aSDomain:
                     nrpspksdomains_B9W61_RS05845_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010064077.1"
                     /locus_tag="B9W61_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05845"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_075347906.1"
                     /sec_met_domain="PF00561 (E-value: 1.7e-16, bitscore: 59.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.6e-15, bitscore:
                     55.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKNVESLKYCVDGPEDAPVLVIGPSLGTTWHMWDRQIPELSQH
                     WRVVRYDLPGHGGAPAHASASVTDLADRLIATLDGLGIQRFGYAGCSIGGAIGADLALR
                     HPQRVASLALVASSPRFGTADEFRQRGVIVRTNGLEPMARTAPERWFTPGFAAAQPAIV
                     EWAVQMVRTTDPGCYIAACEALAAFDIRGALGRIGVPTLVLVGAEDQVTGPAEARTLVA
                     GIPDARLALVPGASHLAPVEQPAAVSDLLLMHFSTSWQQDTSAAIPVLPIAPVPAAPAA
                     PFAPVAEIAPAVPTPETSAATPDARHEQGIKVRREVLGDAHVDAVNASADGFTEDFQEL
                     VTRYAWGEVWSRDGLDRRTRSCITLTALVASGHLEGLAAHTRAALRNGLTPAEIKEVLL
                     QTAVYCGLPAAGAAFAVAQKVIQEETTPPA"
     aSDomain        complement(7411..7740)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W61_RS05845_Abhydrolase_1.1"
                     /evalue="5.60E-22"
                     /label="B9W61_RS05845_Abhydrolase_1.1"
                     /locus_tag="B9W61_RS05845"
                     /protein_end="129"
                     /protein_start="19"
                     /score="70.5"
                     /tool="antismash"
                     /translation="PVLVIGPSLGTTWHMWDRQIPELSQHWRVVRYDLPGHGGAPAHAS
                     ASVTDLADRLIATLDGLGIQRFGYAGCSIGGAIGADLALRHPQRVASLALVASSPRFGT
                     ADEFRQ"
     misc_feature    7778..7793
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.55"
                     /tool="antismash"
     gene            complement(7910..8899)
                     /locus_tag="B9W61_RS05850"
                     /old_locus_tag="B9W61_05850"
     CDS             complement(7910..8899)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378419.1"
                     /locus_tag="B9W61_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05850"
                     /product="nitroreductase family protein"
                     /protein_id="WP_087764406.1"
                     /sec_met_domain="PF00881 (E-value: 3e-09, bitscore: 35.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDRVTEAVPALVAAAVAAPSMHNAQPWRFVHHTDTGVLSLYGDP
                     DRALPVGDPEHRGMHLGCGGALFNLRVAAAREGWNTVAEVFPDRRDPWRLVDVTLEEPG
                     TVPLDRDLADLFPAVAARHTNRSPFSDEQIPPEIFDELCAAALLEGARLAVPSDWHADD
                     LVDLVHDAELHEAASDLMRAEIIAWTRTGRAGEGPEAEGVPSYAFGPRQHDVKVPVRDF
                     GLPRDTHRRATATFEERPQLAVLGTETDDPADWLRAGQAMERILLVATRDGLATSMMSQ
                     PLEWPELRSMARDPASRMGFVHMVFRLGYGPPAAPTPRRPVADVLTVV"
     gene            complement(9090..9968)
                     /locus_tag="B9W61_RS05855"
                     /old_locus_tag="B9W61_05855"
     CDS             complement(9090..9968)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512513.1"
                     /locus_tag="B9W61_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05855"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_047179563.1"
                     /transl_table=11
                     /translation="MTSAELTTAPTLRIPGPATPYQGDIARYWDGEARPVNLRLGDVDG
                     LYHHHYGIGEVDTASLGDPEDSESEKKLITELHRLESAQAEFLLGHLGDIGRDDTLVDA
                     GCGRGGSMVMAHQRFGCSVEGVTLSAKQADFANGRAAELGIGDHVRARVCNMLSTPFAT
                     GSAAASWNNESSMYVDLDDLFAEHSRVLKVGGRYVTITGCWNPRYGQPSKWVSQINAHF
                     ECNIHSRREYLRAMADNRLVPQAVIDLTPDTLPYWELRATSSLVTGIEDAFINSYRDGS
                     FQYLLIAADRV"
     gene            complement(10001..11326)
                     /locus_tag="B9W61_RS05860"
                     /old_locus_tag="B9W61_05860"
     CDS             complement(10001..11326)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378420.1"
                     /locus_tag="B9W61_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05860"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_087764407.1"
                     /sec_met_domain="T1TS (E-value: 5.7e-67, bitscore: 225.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVPELPPPQSSLPEAVTRFGATVLGAVAARAHDTDAVGGPTGGH
                     PLPGPPAGLPFGPPATAVPPSSVPPIAVPATDASGEGAGLERLLRGPHGLGTAGLRLTP
                     REEPPVTAAPREGRPIPGLYHHPVPEPDEARVDEVSRRIKAWALDEVSLYPEEWEEQFD
                     GFSVGRYMVGCHPDAPTVDHLMLATRLMVAENAVDDCYCEDHGGSPIGLGERLLLAHTA
                     LDPLYTVREYQPEWADSLHADAPRRAYRSAMDYFVRAAGPSQADRLRHDMARLHLGYLA
                     EASWAQQDQVPEVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHARADMQKVIALASN
                     ATTIVNDLYSYTKELDAPGRHLNLPVVIAEREGLSDQDAYLKSVEVHNELMHDFETEAA
                     ALAAACPVPVVQRFLRGVAAWVDGNHHWHQSNTYRYSLPDFW"
     gene            complement(11433..12845)
                     /locus_tag="B9W61_RS05865"
                     /old_locus_tag="B9W61_05865"
     CDS             complement(11433..12845)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965306.1"
                     /locus_tag="B9W61_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05865"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_087764408.1"
                     /transl_table=11
                     /translation="MTVDSSSEARLEVPRQSSLGTAAARNLASTTKSAPQMQEITSRWL
                     LRMLPWVETKGGAYRVNRRLTYTVGDGRVEFVQDGTAVRVIPQELGELALLRDFDDAEV
                     LTAIADRCVQRDFRAGETLVERGTAADQLHLIAHGRIGRTSAGSYGDEVTLDVLADGDH
                     FGEDSLLDDDAQWTQTATAETSGTLLTLSRADFAAVVANSPDLRAHLAEFTARSGQRQN
                     HRGEAEIAMSAGHVGEHDLPGAFADYELKPREYELSVAQTILRVHTRVADLYNGPMNQT
                     EEQLRLTIEALRERQEHELINNREFGLLHNADFKQRIQTHSGPPTPDDLDELLCRRRGT
                     KFFLAHPRTIAAMGREFNARGLYPDHTDLGGQQVPAWRGVPILPCGKIPITPERTSSIL
                     AMRTGEENQGVIGLRQTGLPDEYEPGLSVRFMGIDEKAIISYLVSTYYSAAILVPDAVG
                     VLENVQIANWPR"
     gene            complement(13378..13974)
                     /locus_tag="B9W61_RS05870"
                     /old_locus_tag="B9W61_05870"
     CDS             complement(13378..13974)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612389.1"
                     /locus_tag="B9W61_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05870"
                     /product="hypothetical protein"
                     /protein_id="WP_047179560.1"
                     /transl_table=11
                     /translation="MIAAEHPVVPHQSESPGDGEGKPPEDRRHVFKRRFITATIIVLLI
                     GIPAGYLLISAGQSRRSGQDKEAEAAAQGLREGWPSKMQRRIFEIPIPGNGQGVQYYET
                     NNWKASRMYAKFRTTSAGLDRFLTGVGTGRAALEPDTIDISPRDIKITGWSFGPGEEWA
                     STTHKNKKPRPTQNITVNMTDPASPVVYVVSAATP"
     gene            complement(14047..15213)
                     /locus_tag="B9W61_RS05875"
                     /old_locus_tag="B9W61_05875"
     CDS             complement(14047..15213)
                     /EC_number="2.7.1.2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965308.1"
                     /locus_tag="B9W61_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05875"
                     /product="ROK family glucokinase"
                     /protein_id="WP_047179559.1"
                     /transl_table=11
                     /translation="MSTYRDFAHRGSARATVLKTVGTKERRSHLTAPRVPTVGIDIGGT
                     KVMAGVVDADGNILEQLRTETPDKSKSPKVVEDTIVELVLDLSDRHDVHAVGIGAAGWV
                     DADRSKVLFAPHLAWRDEPLRDAIASRLVVPVMVDNDANTAAWAEWRFGAGRGEDHLVM
                     ITLGTGIGGAILEDGQVKRGKYGVAGEFGHMQVVPSGHRCPCGNRGCWEQYSSGNALVR
                     EARELAAADSPVAHYLLDRVKGNVSDITGPLITELAREGDAMCIELLQDIGQWLGIGIA
                     NLAAALDPSCFVIGGGVSAADDLLINPARDAFKRHLTGRGYRPEARIAKAQLGPEAGMV
                     GAADLARLVARRFRRANRRRVERYERYAQIYDQAASTIRNTRPTRTAD"
     gene            complement(15347..16216)
                     /locus_tag="B9W61_RS05880"
                     /old_locus_tag="B9W61_05880"
     CDS             complement(15347..16216)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378422.1"
                     /locus_tag="B9W61_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05880"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_087764409.1"
                     /transl_table=11
                     /translation="MTATPEETAGATGGTTTGPLVELDDVSKFYGNIKALEHVSLEVHA
                     GEITCVLGDNGAGKSTLIKIIAGLHRHDAGRFLIEGEETVLANPRDALDRGIATVYQDL
                     AVVPLMPVWRNFFLGSEPTVGVGPFKRLDVRKMRETTRTELLRMGIDLRDVDQPIGTLS
                     GGERQCVAIARAVYFGAKVLVLDEPTAALGVKQSGVVLKYVAAARDAGLGVVLITHNPH
                     HAHLVGDRFILLKRGAMSGSHTKDDVTLDELTRQMAGGSELEELSHELERTPTPTLPGA
                     HGTKDGTP"
     gene            complement(16213..17259)
                     /locus_tag="B9W61_RS05885"
                     /old_locus_tag="B9W61_05885"
     CDS             complement(16213..17259)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961417.1"
                     /locus_tag="B9W61_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05885"
                     /product="ABC transporter permease"
                     /protein_id="WP_047179557.1"
                     /transl_table=11
                     /translation="MSGSTAAPGRLDERLVRTSPLRKLLGRPELGSVVGAAAVFLFFAI
                     VADSFLQASSLGTVLYAASVLGIMAAPVALLMIGGEFDLSAGVMVTSSALISSMFSYQM
                     TANVWVGVFVSLLVTLAIGAFNGFMLTRTKLPSFIITLGTFLMLTGLNLGFTKLISGTV
                     STKAIGDMEGFASARALFASTLTLGGVEFKVTILWWAALVGVATWILLRTRFGNWIFAV
                     GGEADAARAVGVPVVRTKIGLYLGVAFAAWVSGQHLLFSYDVVQSGEGVGNELTYIIAA
                     VIGGCLITGGYGSAIGSAVGAIIFGMTSKGIVYAEWNPDWFKFFLGAMLLLATLLNAWV
                     RKRAEATS"
     gene            complement(17256..18236)
                     /locus_tag="B9W61_RS05890"
                     /old_locus_tag="B9W61_05890"
     CDS             complement(17256..18236)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153146.1"
                     /locus_tag="B9W61_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05890"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_087764410.1"
                     /transl_table=11
                     /translation="MGAVLAVVLGASLAGCSSTGGKRAEERAAAEAEGRAAVNTPRWTF
                     AMVTHSGDGDTFWDIVQKGAEQAALKDNINFLYSHNDEANQQAQLVQTAIDKKVDGLIV
                     SLAKPDAMKAVVAKAVKAGIPVVTVNSGSAESKEFGALTHIGQDETIAGEAVGDELNAR
                     GRKKALCVLHEQGNVGHEQRCAGAKKTFDGTMQNLYVDGTNMPDVTASIEAKLQSDKSI
                     DAVVTLGAPFADAAVQAKQTAGSKAEIDTFDLNAKVATGLQADKLGFAVDQQPYLQGYE
                     AVDLLWLYRYNRNVLGGGLPVLTGPQIITKDDADALADYTKRGTR"
     gene            complement(18557..19315)
                     /locus_tag="B9W61_RS05895"
                     /old_locus_tag="B9W61_05895"
     CDS             complement(18557..19315)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961415.1"
                     /locus_tag="B9W61_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05895"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_075347532.1"
                     /transl_table=11
                     /translation="MTAHGTDRPLPLSVDRTSPVPLYFQLAQQLEAAVEQGRLAPGALL
                     GNEVDLAARLGLSRPTVRQAIQSLVDKGLMVRRRGVGTQVVHSKVRRPLELSSLYDDLE
                     AAGQRPATSVLRNTTEPATAEVAAALGVAEGGEVHLVERLRSAHGEPMALLRNHLPLGL
                     LPLTTEELEATGLYRLMRTGGITLHSARQTVGACAADDRQARALSEPVGAPLLTMERTT
                     YDDTGRVVEFGSHVYRADRYAFEFQLLVRA"
     gene            19446..20465
                     /locus_tag="B9W61_RS05900"
                     /old_locus_tag="B9W61_05900"
     CDS             19446..20465
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965313.1"
                     /locus_tag="B9W61_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_05900"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_087764411.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.5e-15, bitscore:
                     56.6, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 7.4e-25,
                     bitscore: 86.0, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGLIGTGRIGTFHAEVLSRHPAVDALLLADAAPERAAGAAART
                     GATAVPVDALFGGEGAAGGPPDAMVICSATSAHAGLIARAARAGLPVFCEKPIALDLPG
                     TLAALAEVEAAGSVLQLGFMRRFDAGYGEARAAVREGRLGRLHTVRAVTSDPAPPPAAY
                     LPLSGGLYRDCLVHDFDILRWVTGREVSEVYATGSDAGPAMFREAGDVDTAAALLTLDD
                     GTLATATATRCNGAGYDVRMELAGERDQIAVGLDDRTPLTSAEPGGSGAPAKPWPGFLE
                     RFAPAYEAELDAFLRVVRGELANPCDGREALHALRIAEACEVSRRERRPVAMSEIPGG"
ORIGIN
        1 agcacccggt gttcggagag ccggccgacc gcgaggaccg cgcccaggac gagcgagagg
       61 acggcggcgt acgcgaacgc cttgagggtg ttgccgagtc cccgcagcag cagttcctgg
      121 atgcccttgt actcgaaggg cgtccacttc tcggcggtga actggtcggt gtcgaagagc
      181 agatagacga tccagccgaa cagcgccagg atcaggaccg tcgaggcgat cccgtacatc
      241 cggtgccgtc tacgggtcac cgggccgggg atgtcgtaga gcgcggtggc cgccgggagc
      301 gtgggcctgc gggtgagggt cttggtcatc gtgccactcc ccagcgcttc tccatcacgt
      361 tgaacaccgc gctgatggtc agggtgatga tcaggtagcc gaccgcgatc cagatgaagg
      421 accagatgat gctgtagccc aactcgttga gggtcttgta ggtgccgagg agttcggtga
      481 cgctgaacgc cccggcgatc gcggagttct tcgccagcgc gatcagcgtc gagccgaccg
      541 gcgggatcac cgaccggaac gcctgcggca gcaccacggt gctgagggtc tgcccgaagt
      601 tcatgccgag gctgcgggcg gcctcgccct ggcccttggg cacggtgttg ataccggagc
      661 gcagcacctc gcagatgaag gccgaggtgt agcagccgag cgccagcacc gcgaagacct
      721 ggaacggcag gacgagcccg aagcggggca ggccgagcag gaccgcgaag aacagcagcg
      781 tcagcggggt gttgcggagc acggtgaccc agaccgtgcc cagcacccgg aaggagccga
      841 cgggcgcgac ccggaaggac gccatcagga agccgaggac gagcgccagc gcggaggcgt
      901 agacggtcag ctcgacggtg ccgaggaagc ccttgccgta gagggagaag ttctctgtca
      961 gtacgtccat gggtggggcc gtcccctcag ttcgccgggt agcggtcgat gggcggcggg
     1021 gtcggcgcgg gcgctccgga gagccccagc gtcgcttcgt acgccttctt ccagttgccg
     1081 ttcttctcgt tggcctccag cgcgtcgttg agcgcgttgc gcagcgcgtt gtcgtcgcgc
     1141 ggtacgccga tgccgtacgg ctcctcggag aagggcttgc cgacgacctt catctcgtcg
     1201 ggcgccttcg ccgcgaagcc cagcaggatc gcgtcgtcgg tggtgacggc gtcgacctgg
     1261 taggtgagga ggttgtcgac gcagatcgag tacgtgtcgt acgcgacgag cgtcgccttg
     1321 ggatagtcgg cggcgatgcg ctggtagggc gtggagccgg ccgccgaaca gacggtcttg
     1381 cccgccaggt cctggggccc gtcgatgtcg ttctcgtcgg tgcgcaccag caggccctgg
     1441 cccgccatgt agtacggacc ggcgaagccg acgagcttct tgcgcatgtc gttgatggtg
     1501 tacgtgccga cgtagtagtc gatctggccg ttctgcagtg ccgtctcgcg gttggcggag
     1561 gcgatcgtgc ggaagcggat cgtcttcggt tcgaagccga gcgaggccga catcatccgg
     1621 gcgatctcga tgtcgaaccc ggagtagatc ccgctcgccg ggtccttctc ccccaggtac
     1681 ggctggtcct ccttggcgcc gaccaccaga tagccgcgct tcttcgcctt ggtccaggtg
     1741 cgcgagtcgg gcagttcgaa gccggtgtcg acctggtaca ccggcagcgc ttcggccttc
     1801 ggacccttga ccggcgggct gccgtccttg ccgcagcccg cggccagtgc ggcgagcagg
     1861 agaccggcca cgagggcggc ggccctgccc gtacgcgtgt tcctcgtacg caacatgaag
     1921 cctcccctca gtgcttgagg atcttggaca ggaagtcctt ggcgcggtcg ctcgaagggt
     1981 tcgtgaagaa gtcctccggg gtgcggtcct cgacgacgca gccgtcggac atgaacacca
     2041 cgcggttggc cgcggagcgg gcgaagccca tctcgtgggt gaccacgacc atggtcatgc
     2101 cgtcccgggc gagttgctgc atgacctcca gcacctcgtt gatcatctcc gggtcgagcg
     2161 ccgaggtggg ctcgtcgaag aggagcgcct tggggtccat ggccagggcg cgggcgatgg
     2221 ccacgcgctg ctgctgaccg ccggagagct gggcggggaa cttgtcggcg tgggcggcca
     2281 gtccgacccg ctcaaggagt tcgcgggagc gacggtcggc ctcgtccttc ttgcgcttgc
     2341 ggaccttgag ctgggccagc gagacgttgt ccagcacggt cttgtgggcg aagaggttga
     2401 acgactggaa gaccatgccg acttcggcac ggagctgggc caggcccttg ccctcctcgg
     2461 gaaggggtct gccgtcgatc atgatgctgc cggactcgat cgtctccagc cggttgatcg
     2521 cccggcacag ggtggatttc cccgagccgg aggggccgat gaccaccacc acctccccgc
     2581 ggccgacggt gagattgatg tcctgaagta cgtgcaactc cccgaagtgt ttgttgacgt
     2641 cccgcagttc gatcaacgga tcgacggcca tgcgctgccc tacccacttg tcgctgtgtc
     2701 gaggtcagcg caaactatcc atcccgaaaa gggacttcgc acccgacacg cgtaaatggc
     2761 gcaaaaggct ttttaactgg attagctgag gagaggaggc cccggtcggc cgtcggctca
     2821 gttctcggcg gactccgcgt agacctggga gagctcgggg ctgcccgcca tcgcccagtc
     2881 gagaccggca gcgacgacgt cgatctcccg cccggactcc agccgcacca cgggctgacc
     2941 gctcggccag acgtcccacg ccgcacccgg gacggtccgc acgatcacgg tgccgaggta
     3001 gagaccggcg tcgttgccga gccagggaag ctcctcgggg tcgtcgcgcc agcggggcgg
     3061 caactggtcg agcgcggcca acgaggccgg tgtgtcgtcg agttcgagtc cgtgctgccc
     3121 cgcccggacg cgcagcagtt cgcattcggc gagcagttcg gccacgccgt cggggtctgc
     3181 ctcgacggcg gcggcgagtg cgcccgaacg cgtaccaccc tgacgcttac gccagttgtc
     3241 caagaaaggg atgttcatac cactagggtc ccatcccggc caggttccgc accacagggc
     3301 gcgcggcgtt caccgatccc ccaccccacc tcggccgcgc atccgagcag atatctaaag
     3361 tgcgcacatg agtgcacacg cttacgtttc ggaactgttc tcactggaag gccgggtggc
     3421 ggtggtcacc ggcggcagct cgggcatcgg ccgggcgatc accggcgccc tggcccgggc
     3481 cggcgcgcgc gtcgtcgtgg tggcccgccg ggaggccgag ctgagggcga ccgcggacga
     3541 gctgaccgcc gagggctgcc gggccgcctg ggtgagcgcg gacctcggca ccgccgaggg
     3601 cgtgcgcgcg ggagcggagg gggccgccca ggcgttcggg gagccggaca tcctggtgaa
     3661 ctgcgccggg atcaatctgc gcccgccgat ggccgagctc ggcgaggacg tctgggacac
     3721 cacgatggcg gtgaacctga aggcgccgtt cctgctgggg cagcgcttcg ggcccgggat
     3781 ggccgagcgc ggctacgggc ggatcatcca cgtcacctcg cagcaggcgc accgggcctt
     3841 cgtggacagc ggcgcctacg gggtgtccaa gggcggtctg gaatccctgg cccgctccca
     3901 ggcggaggcg tggtccgcgc acggcgtcac cgtgaacacg ctggtgcccg ggttcgtgct
     3961 gaccccgctg aacgcgcgtc tccagtcgga cccggaaaag gtggcgtcgc tcgccgcccg
     4021 gaccctggtc ggccgcaacg gcctcgcgga ggacttcgcg ggggccgcgg tgttcctggc
     4081 ggggcgttcc tcggcgtacg tcaccgggca gtcggtgttc gtggacggcg ggttctcggt
     4141 gcactgagaa cccgccgccc gcgccgcggg ggccgtccgg tcagggcttc tgctgccaca
     4201 gggcggcggc cgcttcggtc accgccgcct cgacggccgc cgagacggcg tccttctcca
     4261 ctccgaggcc gctcagcacg ccggatccgc cctcgaactc cagcagggcc agcaggatgt
     4321 gctcggtgcc gacgtagttg tgcccgagcc gcagcgcctc gcggaaggtc agctccagga
     4381 ccttgcggga gtccgcgtcg tacgggatca gctcgggcac ctcttcggcc gcggccggca
     4441 gcgcggcgac cgccgccgca cggagggcgt ccggggtgat ctccgggccg aggagcaccc
     4501 cggccgcgat ggactcgggc tcggcgagca ggccgagcac caggtgggcc gggacgatct
     4561 cggcgtgccg ggcggcctgg gcctcgttgt gagcggccat gacgacgttg cgggcgcgct
     4621 gggtgaagcg gccgaagccc tggctcgggt ccaggtcgga ggcgccgtcg cccttcttgg
     4681 gcacgaagcg cttctgggcc gcctggcggg tgactcccat gctccggccg atgtccgtcc
     4741 aggaggcgcc ggaacggcgc gcctggtcca cgaagtggcc gatcagatgg tcggccacgt
     4801 cgccgaggtg gtcggcggcg atgaccgcgc cggagagctg ccccagagca tcggtgttgg
     4861 acttcttgat ggcctcgatc aggtcgtcga ggcgcacgga cggtgcggcg ggaagaggct
     4921 gcgtcatgcg tcaaccgtag gttgacaccc cattggtgtc aaccttgggt tgtcagcatg
     4981 gcgtggcctc agcccccgcg ggcccccgcg gatcgcgcct cagaggtcga ggtcgacgac
     5041 caccggggca tggtccgacg cgcccttgcc cttgcgctcc tcgcggtcga cgtagctgtc
     5101 cttgacggcg gcgacgaacg gggcgttgcc gaaggtgagg tcgatccgca tgcccttgtt
     5161 cttggggaac ctcagctcgc ggtagtccca gaaggtgaag gcgcggtcgt acttgagggg
     5221 gcggggcagg acctcgctca ggccctccgc ctccagggcc gtgagggcgg cgcgctcggc
     5281 gggcgtcaca tgcgtggcgc cggcgaacag cgccgggtcc cagacgtcct catcggtcgg
     5341 ggccacgttg aagtcgccga ggaccgcgaa cggcagtgcc ttcgcggcgt ccgccgccac
     5401 ggccttccgc agggcctcca gccagcgcag cttgtacgcg tagtgctcgt gctcgacctc
     5461 gcggccgttg ggcacgtaca ccgaccagag gcgcagcggg ccgcacgtcg ccgagatcgc
     5521 gcgcggctcc tgcaccccgt cgtactccgg gccgtcgggc agcccggtga cgacgtcgga
     5581 gaggccgacg cgggagagca gcgcgacccc gttccaccgg ccggtggcgt tgaccgcgga
     5641 ctcataaccc agctcggcga gggcggcggt ggggaactgc tccgccgtgc acttggtctc
     5701 ctggatgcac agcacatcgg tgccgctgct ctccagccag gccagaagcc tgggcagccg
     5761 ggcggtgatc gaattgacgt tgtacgtggc gatgcgcatg gcagccaacc tagccgctcc
     5821 cactgacagc ggccgccggg ctcacagctc ggtggtgccg cccggggcca gccggccgtg
     5881 gtccgcgccg cccagggccc cgatctggtt gtcgtagatg ggccgtgcca gatcggtcag
     5941 cagggcgtcg tggacgtcga tggcgcgccg cggcttcacc tcgcgtacgt agtcgatgac
     6001 ctcggagatc ttgctccagg gggccatcac cggcagcagc agcgtgtcca cggagcgctc
     6061 ggggacggtg agcgcgtcgc cggggtggaa gaccgaaccg tccacgagga agccgacgtt
     6121 ggtgatcctc gggatgtccg ggtggatcac cgcgtgcagt tcgccgtgca cggtgacgtc
     6181 gaatccggcg gcggagaacg cgtccccgtc gcccacggtg tgcacccgcc cggggaaggc
     6241 cgccgaaagc tgctcggcca cgctgcgcag cgtccagatc tcggccgccg ggttcgcctc
     6301 caggcccacc cgcagccgcg cctcgttgaa gtggtccggg tgttcgtgcg tcaccaggac
     6361 gacatcggcg ccgagcgccg cgtcgtcctc ggagaagccg ccggggtcga tgaccaggac
     6421 ccgcccctcc ttctcgatcc ggacgcagga gtgggtcttc ttggtgaggg tgagagcccc
     6481 ggacgatgcg ttcatggccc catcctgcta cgcgggcggc gtggtttcct cctggatcac
     6541 cttctgcgcg acggcgaagg cggccccggc ggccgggagc ccgcagtaga cggcggtctg
     6601 gagcaggact tccttgatct cggcgggtgt caggccgttg cgcagggcgg cccgggtgtg
     6661 cgcggccagg ccttccaggt ggccggaggc gacgagcgcg gtgagcgtga tgcagctgcg
     6721 ggtgcggcgg tcgagtccgt cccggctcca gacctcgccc caggcgtacc gggtgaccag
     6781 ctcctggaag tcctcggtga atccgtcggc cgaggcgttc acggcgtcga catgggcgtc
     6841 gcccagcacc tcccggcgta ccttgatgcc ctgctcgtgc cgggcgtccg gcgtcgcggc
     6901 ggaggtctcg ggcgtcggga cggccggggc gatctcggcc accggggcga acggggcggc
     6961 gggcgccgcg ggcaccgggg cgatcggcag cacgggaatc gcggccgagg tgtcctgctg
     7021 ccaggaggtg gagaagtgca tcagcagcag gtcgctgacg gcggcgggct gctcgaccgg
     7081 ggcgaggtgc gaggccccgg ggacgagcgc caggcgggcg tccggtatcc cggcgaccag
     7141 cgtgcgggcc tcggcgggtc cggtgacctg gtcctccgcc ccgaccagca ccagggtggg
     7201 cacaccgatc cggcccaggg cgccgcggat gtcgaacgcc gcgagcgcct cgcaggcggc
     7261 gatgtagcac ccgggatcgg tggtgcggac catctgcacg gcccattcga cgatggcggg
     7321 ctgcgcggcg gcgaagccgg gggtgaacca gcgctccgga gcggtgcggg ccatcggctc
     7381 cagaccgttg gtgcggacga tcacgccgcg ctggcggaac tcgtcggccg tgccgaaccg
     7441 gggcgaggag gcgacgagcg ccagcgaggc cacccgctgc ggatgtctca gtgccaggtc
     7501 cgcgccgatc gccccgccga tcgagcagcc cgcgtagccg aaccgctgga tgccgagccc
     7561 gtccagcgtc gcgatcagcc ggtcggccag atcggtgacg gaggcggagg cgtgggcggg
     7621 ggcgccgcca tggccgggca ggtcgtagcg gacgacccgc cagtgctggg acagctcggg
     7681 tatctggcgg tcccacatat gccatgtggt acccagcgag gggccgatga ccaggaccgg
     7741 agcgtcttcc ggcccgtcga cgcagtactt cagggactca acgttcttct cactcaccca
     7801 ctcacgctcc cacatctcac gtccgcctcg tgagctgggg ccggagcgct cgccggatct
     7861 ccccacctgt ccgcaggtgg tgcggccggg cacggcacgc accggtgcgt cacacgacgg
     7921 tgagcacatc ggcgaccggt ctgcgcgggg tgggcgccgc cggggggccg taaccgaggc
     7981 ggaagaccat gtggacgaag cccatcctgg acgcgggatc gcgggccatc gacctcagct
     8041 ccggccactc cagcggctgc gacatcatcg aggtcgccag gccgtcccgc gtcgccacga
     8101 gcaggatccg ctccatggcc tgccctgccc tgagccagtc ggcggggtca tccgtctccg
     8161 tgccgagcac cgccagttga gggcgctcct cgaacgtggc cgtggcacgg cggtgcgtgt
     8221 cccggggcag cccgaagtcc cgcacgggca ccttcacgtc gtgctggcgc gggccgaacg
     8281 cgtaggaggg cactccttcg gcctccggtc cttcccccgc cctccccgtg cgcgtccagg
     8341 cgatgatctc cgcccgcatg agatcgctgg cggcctcgtg gagctccgcg tcgtgcacga
     8401 ggtcgacgag gtcatcggcg tgccagtcgc tcggaacggc gagccgggcc ccttccagga
     8461 gcgcggccgc gcacagctcg tcgaatatct ccggcgggat ctgctcgtcg gagaacgggg
     8521 agcggttggt gtgccgggcc gccacagcgg ggaagaggtc cgccagatcc cggtcgaggg
     8581 gcacggtacc gggctcctcc agcgtgacgt cgaccaggcg ccaggggtcc cgacggtccg
     8641 ggaacacctc ggcgaccgtg ttccagccct cccgggcggc ggccacccgc agattgaaca
     8701 gcgcgccccc gcatccgaga tgcatgcccc ggtgctcggg gtcgccgacc ggaagagcac
     8761 ggtccggatc gccgtacagg gagaggacgc cggtgtccgt gtggtggacg aatctccacg
     8821 gctgggcgtt gtgcatggac ggcgcggcga cggccgccgc caccagtgcc gggaccgctt
     8881 cggtgactcg gtctctcatc acagttcctt ctcgctccac aaggccgtcg cgccgccccg
     8941 gtgaaccgcg atgcgtccgg ccgcttccac ccgatcggac cgcctccttc caaactaacc
     9001 ccgcggccgt gccggctcat gccgaacgcc gagatggccg gccgccaccg ggatgtcccc
     9061 ggtgacggcc ggccctgggc cgggcgccgt cagacgcggt cggccgcgat gaggaggtac
     9121 tggaaggacc cgtcccggta ggagttgatg aacgcgtcct cgatccccgt gaccagcgag
     9181 gacgtggcgc gcagctccca gtagggcagg gtgtcggggg tcaggtcgat gacggcctgc
     9241 ggcacgaggc ggttgtcggc catggcgcgc aggtactccc ggcgcgagtg gatgttgcac
     9301 tcgaagtgcg cgttgatctg cgaaacccac ttcgagggct ggccgtagcg cgggttccag
     9361 cagccggtga tggtcacgta gcgaccgccg accttcagga cgcgggagtg ctcggcgaag
     9421 aggtcgtcca ggtccacgta catgctcgac tcgttgttcc acgacgccgc ggcggaaccg
     9481 gtcgcgaagg gtgtggagag catgttgcag acgcgggcgc ggacgtggtc gccgattccc
     9541 agttccgcgg cgcgcccatt ggcgaagtcg gcctgcttgg ccgacagcgt cacgccttcc
     9601 acggaacagc cgaagcgctg gtgcgccatc accatcgagc caccccggcc gcagcccgcg
     9661 tccacgagcg tgtcgtcgcg cccgatgtca ccgaggtgcc ccagcaggaa ctcggcctgg
     9721 gccgactcca gccggtgcag ctcggtgatc agcttcttct cgctctcgct gtcctcgggg
     9781 tcgccgagcg aagcggtgtc gacctcaccg atgccgtagt ggtggtggta gaggccgtcg
     9841 acatcgccga ggcgtaggtt cacgggccgg gcctccccgt cccagtagcg ggcgatgtct
     9901 ccctggtagg gcgtcgcggg gcccgggata cgcagggtgg gggcggtggt gagttcagcg
     9961 ctggtcacag atggttcctg tctcttgacg gatgccgggc ctaccagaag tcgggcaggc
    10021 tgtagcggta ggtgttcgat tggtgccagt ggtgattgcc gtcgacccag gcggcgacgc
    10081 cccgcaggaa acgctgcacg accgggacgg ggcaggcggc ggccagcgcc gcggcctcgg
    10141 tctcgaagtc gtgcatcagc tcgttgtgga cctcgaccga cttgagatag gcgtcctggt
    10201 cggacagccc ctcgcgttcg gcgatcacga cgggcaggtt cagatgccgg cccggggcgt
    10261 cgagctcctt ggtgtacgag tagaggtcgt tcacgatcgt cgtggcgttg gaggccaggg
    10321 cgatgacctt ctgcatgtcg gcccgggcgt gcaggtccgc cgggagctcg taaccgccga
    10381 cggtgtcggt gatggtgggg cagggccgga agttgttgaa ctggcgcatc gccaggtact
    10441 cccagacctc ggggacctgg tcctgttgcg cccaggacgc ctcggcgaga tacccgaggt
    10501 gcagtcgcgc catgtcgtgg cggagccggt ccgcctggga ggggccggcc gcgcggacga
    10561 agtagtccat ggcggagcgg taggcgcgcc ggggggcgtc cgcgtggagc gagtccgccc
    10621 actccggctg gtactcgcgc acggtgtaga gggggtcgag cgcggtgtgc gcgagcagaa
    10681 gccgctcgcc caggccgatg ggggacccgc cgtggtcctc gcagtagcag tcgtccaccg
    10741 cgttctcggc gaccatcagc cgggtggcga gcatcaggtg gtcgacggtg ggcgcgtccg
    10801 gatggcatcc gaccatgtag cggcccacgg agaagccgtc gaactgctcc tcccactcct
    10861 cggggtacag ggagacctcg tccagcgccc aggccttgat cctccggctg acctcgtcga
    10921 cgcgcgcctc gtcgggctcg gggaccgggt ggtggtacag gcccgggatc ggccggcctt
    10981 cccggggggc cgccgttacg ggcggctcct cgcggggtgt cagccgcagc ccggccgtgc
    11041 ccaggccgtg gggcccgcgc agcagccgct ccagcccggc accctccccg gacgcatcgg
    11101 tcgccggtac ggcgatcggc ggtacggagc tgggcggtac ggcggtggcc ggcgggccga
    11161 agggcagtcc tgcgggcggg cccggcaggg ggtgtccgcc ggtcggcccg ccgacggcgt
    11221 cggtgtcatg ggcgcgagcc gcgaccgcgc cgagcacggt cgccccgaag cgggtgacgg
    11281 cctccggcag gctcgactgc ggaggtggca gctcgggcac gggcatgcgt ggctctcctt
    11341 ggtggggggc gaatgttccg gggcgtccgg gatggcggcc cgcttcgcgg gggccggccg
    11401 ggtgggccgg gccgccgcgt gggccgcgac cactacctgg gccagttggc gatctgcacg
    11461 ttctccagga cgccgaccgc gtcgggcacg aggatggcgg cggagtagta ggtgctgacg
    11521 aggtaggaga tgatcgcctt ctcgtcgatg cccatgaagc ggaccgagag gcccggttcg
    11581 tactcgtccg gcaggccggt ctggcgcaga ccgatgacgc cctggttctc ctcgccggta
    11641 cgcatggcga ggatcgagct ggtcctctcc ggggtgatgg ggatcttgcc gcagggcagg
    11701 atcggcacac cgcgccaggc gggaacctgc tggccgccga ggtcggtgtg gtccgggtag
    11761 aggccgcgcg cgttgaactc gcgccccatc gccgcgatcg tccgggggtg cgcgaggaag
    11821 aacttggtgc cccggcggcg gcagagcagc tcgtccaggt cgtccggggt cggcgggccg
    11881 gaatgcgtct ggatgcgctg cttgaagtcg gcgttgtgga gcagaccgaa ttcccggttg
    11941 ttgatcagct cgtgctcctg gcgctcccgc agcgcctcga tggtgagcct gagctgttcc
    12001 tcggtctggt tcatcgggcc gttgtagagg tcggcgaccc tggtgtggac ccgcaggatg
    12061 gtctgggcga ccgagagttc gtactcgcgc ggcttcagtt cgtagtcggc gaacgcgccg
    12121 ggcagatcgt gctcgccgac gtggccggcc gacatcgcga tctccgcctc gccccggtgg
    12181 ttctgccgct gcccggagcg tgcggtgaac tcggcgaggt gggcccggag gtccggcgag
    12241 ttcgccacga cggccgcgaa gtcggcgcgg gacagggtga gcagcgtgcc cgaggtctcg
    12301 gcggtggcgg tctgcgtcca ctgggcgtcg tcgtccagca ggctgtcctc gccgaagtgg
    12361 tcgccgtccg ccaggacgtc cagggtgacc tcgtcgccgt agctgccggc ggaggtccgg
    12421 ccgatccggc cgtgcgcgat cagatggagc tggtccgcgg ccgtgccccg ctcgaccagc
    12481 gtctcccccg cccggaagtc acgctggacg caccggtcgg cgatggccgt cagcacctcg
    12541 gcgtcgtcga agtcccgcag cagggccagt tcgcccagct cctgggggat gacccggacc
    12601 gcggtcccgt cctggacgaa ctccacccgc ccgtcgccca cggtgtaggt gagccgccgg
    12661 ttgacccggt aggcgccgcc cttggtctcg acccagggaa gcatccgcag cagccagcgg
    12721 gaggtgatct cctgcatctg cggggcggac ttcgtcgtgc tggcgaggtt gcgggcggcg
    12781 gccgtcccca ggctggactg gcggggcact tccagccgcg cttccgagct cgagtcaaca
    12841 gtcatcgggc aggctctcct tggtcggagc gggaacgcgc atagcggacg cgaacctacg
    12901 aaagggtgaa aaagtgaggc aaagggacga tatgaaggga atccctccag atcagatcca
    12961 cgggaacact aaggtcccct ccggcctccg gaccaaggaa atccgccgac attagctcga
    13021 tgcgatgatc gcgcccggga gatgtttgcc cctgtgccga cggatttcag ccgtcatcgg
    13081 agcagggtgc acggcagcgc tccgggccca cacggctcga agcctcggaa gcgcgacgaa
    13141 atccggccgg tcggggcaga ccgacggcga ggatgacgcg cgggacacgg tagagggccc
    13201 tcgcggacac gacagcacgc gaacacgaca gcgcgcggac acagcacgcg gacacactgc
    13261 ggccccggcg gtggcttacc gccggggccg acacacacgc gcgccgccac cgggtcaatg
    13321 cgatcggtgg cggcgcggcg cgcccggggc cgggtcgacg tgctcagcgg ctcccgctca
    13381 gggggtcgcc gccgagacga cgtacacgac cggactggcc gggtcggtca tgttgaccgt
    13441 gatgttctgg gtcgggcgcg gcttcttgtt cttgtgcgtg gtgctggccc attcctcgcc
    13501 cgggccgaag gaccagccgg tgatcttgat gtcccggggg ctgatgtcga tcgtgtcggg
    13561 ctccagcgcc gcgcgtccgg tgcccactcc ggtcaggaag cggtcgagac cggcggaggt
    13621 cgtccggaac ttcgcgtaca tccggctggc cttccagttg ttggtctcgt agtactggac
    13681 gccctgcccg ttgccgggga tcgggatctc gaagatccgg cgctgcatct tggagggcca
    13741 gccctcgcgg agcccctggg cggccgcctc ggcctccttg tcctggcccg agcggcggct
    13801 ctgaccggcc gagatcagca gatagccggc cgggatgccg atcagcagca cgatgatcgt
    13861 cgcggtgatg aaacgccgtt tgaacacatg ccgccggtcc tcgggcggct tgccctcgcc
    13921 gtcgcccgga gactccgact ggtgcggcac cacggggtgc tcggctgcga tcatgatcag
    13981 gtgatcccta agggtgctgc gatgacggcg tactgaaggg tggacgccga aaagggcggc
    14041 tgcggttcag tcagcggtac gggtggggcg cgtgttgcgg atggtgctcg ccgcctggtc
    14101 gtagatctgg gcgtaccgct cgtaccgctc gacgcgccgc cggttggccc ggcggaatcg
    14161 gcgggcgacc agcctggcca ggtccgcggc gccgaccata cccgcctcgg ggccgagctg
    14221 cgccttggcg atcctggcct cggggcggta gccgcggccg gtgaggtggc gcttgaaggc
    14281 gtcccgggcg gggttgatca ggaggtcgtc ggcggcgctg acaccgcctc cgatcacgaa
    14341 gcaggagggg tcgagcgcgg cggccagatt ggcgatgccg atgccgagcc actggccgat
    14401 gtcctggagg agttcgatgc acatcgcatc gccctcgcgg gccagttcgg tgatgagcgg
    14461 cccggtgatg tcggagacgt tccccttcac ccggtccagc aggtagtggg cgaccgggga
    14521 gtcggcggcg gccagttccc tggcctcgcg gacgagggcg ttgccggagc tgtactgctc
    14581 ccagcagccc cggttgccgc aggggcaccg gtggcccgag ggcacgacct gcatgtggcc
    14641 gaactcaccg gccacgccgt acttgccgcg cttgacctgg ccgtcctcca ggatcgcgcc
    14701 gccgatgccc gtaccgaggg tgatcatgac caggtggtcc tcgccccggc ccgctccgaa
    14761 gcgccattcc gcccaggcgg cggtgttggc gtcgttgtcg accatgacgg ggacgacgag
    14821 gcgggaggcg atggcgtcgc gcaggggctc gtcgcgccag gcgaggtgcg gggcgaacag
    14881 gaccttggag cggtcggcgt ccacccagcc cgccgcgccg atgcccaccg cgtggacgtc
    14941 gtggcggtcg gagaggtcca ggaccagttc gacgatggtg tcctcgacga ccttggggct
    15001 cttggacttg tcgggcgtct cggtgcggag ctgttccagg atgttgccgt cggcgtccac
    15061 gacgcccgcc atcaccttgg tgccgccgat gtcgatcccg accgtgggga cccggggggc
    15121 ggtgaggtgc gagcggcgtt ccttggtgcc gacggtcttg aggacggtgg cgcgggcgga
    15181 gccgcggtgt gcgaagtcgc ggtacgtgct catcgtccct gcggggtctg gggggccggg
    15241 ccgctgtcgc ggccggcggc ggacgacgcc cgccgggctc gattctgcca ctgcccggcc
    15301 ccggggagcc gttgggcggg gtcggccgcg ccggggcggt cgccgctcag ggagtcccgt
    15361 ccttcgtgcc gtgggcgccc gggagggtgg gggtcggggt gcgttccagc tcgtggctga
    15421 gctcctccag ctcgctgccg cccgccatct gccgggtcag ctcgtccagc gtgacgtcgt
    15481 ccttggtgtg gctgccggac atcgcgccgc gcttgaggag gatgaagcgg tcgccgacga
    15541 ggtgggcgtg gtgcgggttg tgcgtgatga ggaccacgcc gaggccggcg tcgcgggcgg
    15601 ccgccacgta cttgaggacc acgccggact gcttgacgcc gagggcggcg gtcggctcgt
    15661 ccaggaccag gaccttcgcg ccgaagtaga cggcgcgggc gatggccacg cactggcgtt
    15721 cgccgccgga cagggtgccg atgggctggt cgacgtcgcg caggtcgatg cccatgcgca
    15781 gcagttcggt acgggtcgtc tcgcgcatct tccggacgtc gaggcgcttg aaggggccga
    15841 ccccgacggt gggctcggag ccgaggaaga agttccgcca gaccggcatc agggggacga
    15901 cggcgaggtc ctggtagacg gtggcgatgc cccggtccag ggcgtcgcgc gggttggcga
    15961 ggacggtctc ctccccctcg atcaggaagc gtccggcgtc gtgccggtgc agccccgcga
    16021 tgatcttgat gagggtggac ttgccggcgc cgttgtcccc gaggacgcag gtgatctcgc
    16081 ccgcgtggac ctccagcgag acatgctcca gggccttgat gttgccgtag aacttggaca
    16141 cgtcgtccag ctcgaccagc ggcccggtgg tcgttccccc ggtcgctccc gcggtctctt
    16201 caggggtggc cgtcatgacg tcgcctccgc gcgcttgcgc acccacgcgt tgagcagggt
    16261 ggccaggagc agcatcgctc ccaggaagaa tttgaaccag tccgggttcc actcggcgta
    16321 cacgatgccc ttgctggtca tgccgaagat gatggcgccg acggccgagc cgatcgcgga
    16381 gccgtagccg ccggtgatca ggcagccgcc gatgacggcg gcgatgatgt acgtcagctc
    16441 gttgccgacg ccctcgccgg actggacgac gtcgtagctg aacagcaggt gctggccgga
    16501 gacccaggcg gcgaaggcga cgcccaggta gagcccgatc ttggtgcgga cgaccgggac
    16561 gccgaccgcg cgggcggcgt ctgcctcgcc cccgacggcg aagatccagt tgccgaagcg
    16621 ggtacggagg aggatccagg tggccacgcc gacgagcgcc gcccaccaca ggatcgtcac
    16681 cttgaactcg acgccgccga gggtcagcgt cgaggcgaac agcgcgcggg ccgatgcgaa
    16741 gccctccatg tcgccgatgg ccttggtgga gacggtgccg ctgatgagct tggtgaagcc
    16801 gaggttcagg ccggtcagca tcaggaacgt gccgagcgtg atgatgaagc tcggcagttt
    16861 ggtgcgggtc agcatgaagc cgttgaacgc gccgatggcg agcgtgacca gcagcgacac
    16921 gaagacgccg acccagacgt tggccgtcat ctggtagctg aacatcgagg agatcagcgc
    16981 ggagctggtc accatgacgc cggcggacag gtcgaactcg ccgccgatca tcagcagggc
    17041 gaccggtgcg gccatgatgc cgaggacgga ggccgcgtac agcacggtgc cgaggctgga
    17101 ggcctggagg aagctgtcgg cgacgatcgc gaagaacagg aagacggccg cggcgccgac
    17161 gaccgagccg agctcggggc ggccgaggag cttgcgcagc ggcgaggtgc gcaccagccg
    17221 ctcgtccagc cggccggggg cggcggtgga gccgctcatc gcgtgccccg cttggtgtag
    17281 tcggcgaggg cgtcggcgtc gtccttggtg atgatctgcg ggccggtcag gacggggagt
    17341 ccgccgccga ggacgttgcg gttgtagcgg tagagccaga gcaggtcgac ggcctcgtag
    17401 ccctggaggt agggctgctg gtcgacggcg aagccgagct tgtcggcctg gaggccggtg
    17461 gcgaccttgg cgttcaggtc gaaggtgtcg atctcggcct tgctgcccgc cgtctgcttg
    17521 gcctggacgg ccgcgtcggc gaagggggcc ccgagggtga ccaccgcgtc gatgctcttg
    17581 tcggactgga gcttggcctc gatggacgcg gtgacgtcgg gcatgttggt gccgtcgacg
    17641 tacaggttct gcatcgtgcc gtcgaaggtc ttcttcgccc ccgcgcagcg ctgctcgtgg
    17701 cccacgttgc cctgctcgtg caggacgcag agggccttct tgcggccccg cgcgttgagc
    17761 tcgtcgccga ccgcctcacc ggcgatggtc tcgtcctggc cgatgtgggt gagcgcgccg
    17821 aactccttgg actccgcgga gccggagttc acggtgacga ccgggatgcc cgccttgacg
    17881 gccttggcga ccacggcctt catcgcgtcc ggcttggcca gcgagacgat caggccgtcg
    17941 accttcttgt cgatcgcggt ctggacgagc tgggcctgct ggttggcctc gtcgttgtgc
    18001 gagtagagga agttgatgtt gtccttgagg gccgcctgct cggcgccctt ctggacgatg
    18061 tcccagaagg tgtcgccgtc gcccgagtgg gtgaccatgg cgaaggtcca gcgcggtgtg
    18121 ttcaccgcgg cccgtccctc ggcctcggcg gccgcgcgct cctcggcgcg cttgccgccg
    18181 gtgctgctgc atcccgcgag ggaggcgccc agcaccactg ccagcacggc gcccatcgcg
    18241 cgtacccctg tccgaaccct tgccacgacg ccgtgccctt ctactgctgc tcgctgtgct
    18301 gcttgacggg gccggggagt gtacggtccc ggcccggctg cccaagtatc cccgagcccc
    18361 gcccctcggt gcccgcaccc ccagcccgtc cggcgtttga ggacggaccc ttgcgtgggt
    18421 gggcccgacg gacacaggag cctggggcac aggacccgcc gagcgcaacc cgtgtgcacg
    18481 ggacggttcc gtcctcgaac gccggacggg ctgggcaggt cgccggacgg gctggatcag
    18541 cgggttcgca taccgctcag gcgcgtacca ggagctggaa ctcgaaggcg taccgatccg
    18601 cccggtagac gtgcgagccg aactcgacca cccggccggt gtcgtcgtac gtggtgcgct
    18661 ccatcgtgag cagcggggcg cccacgggct ccgacagcgc ccgtgcctgt cggtcgtccg
    18721 cggcgcacgc gccgacggtc tggcgggcgc tgtgcagcgt gatgccaccg gtccgcatca
    18781 gccggtagag gccggtggcc tccagttcct cggtggtcag gggcagcagt ccgaggggca
    18841 ggtggttgcg caggagggcc atcggttcgc cgtgggcgct gcgcagccgt tcgacgaggt
    18901 ggacctcgcc gccctcggcg acgccgagcg cggcggcgac ctcggcggtg gccggttccg
    18961 tggtgttgcg caggacgctg gtggcggggc gctggccggc cgcctccagg tcgtcgtaga
    19021 gcgagctgag ctccagcggg cggcggacct tgctgtggac gacctgggtg ccgactcccc
    19081 ggcggcggac catcaggccc ttgtcgacga gcgactggat ggcctggcgg acggtcggcc
    19141 gggacaggcc gaggcgggcg gcgaggtcga cctcgttccc gagcagggcg ccgggggcca
    19201 gccggccctg ttccacggcg gcctccagtt gctgcgccag ctggaagtag agcggcaccg
    19261 ggctggtgcg gtccacactc agcggcagcg gccggtcggt tccatgtgcg gtcacggggc
    19321 gagcgtagtt cgcttgtccg gacaaagcca tggcgtaccg gggcggggag cggccgatcg
    19381 aggcggctcc gtttgtcagg acaaacgctt gacatggcga ccgggcgaac gccaccttgg
    19441 ggcccatgcg catcggactg atcggaacgg gacggatcgg caccttccat gcggaggtgt
    19501 tgagccgtca ccccgccgtg gacgccctgc tgctggcgga cgcggccccg gagcgggcgg
    19561 ccggagccgc ggcgcggacg ggggcgacgg ccgttccggt ggacgctctg ttcggcggag
    19621 agggcgcggc cgggggcccg cccgacgcca tggtgatctg ttcggcgacc tcggcccatg
    19681 ccgggctcat cgcgcgggcc gcccgcgccg ggctgcccgt cttctgcgag aagccgatcg
    19741 ccctggacct gcccggcacg ctcgccgcgc tcgcggaggt cgaggcggcg ggcagcgtgc
    19801 tccagctcgg tttcatgcgg cgtttcgacg ccgggtacgg cgaggccagg gccgccgtgc
    19861 gggaggggcg gctcggccgg ctgcacaccg tgcgggcggt cacctccgat ccggccccgc
    19921 cgcccgccgc ctacctcccg ctgtccggcg ggctgtaccg cgactgcctg gtccacgact
    19981 tcgacatcct gcgctgggtg acgggccgcg aggtgagcga ggtgtacgcc accggctcgg
    20041 acgccgggcc cgcgatgttc cgggaggccg gggacgtgga cacggccgcc gctctgctca
    20101 ccctcgacga cgggacgctc gccaccgcca ccgcgacccg gtgcaacggc gccgggtacg
    20161 acgtacggat ggagctggcc ggcgaacggg accagatcgc cgtcggcctg gacgaccgta
    20221 cgccgctgac ctcggccgag cccgggggct ccggcgcccc ggcgaagccc tggccggggt
    20281 tcctggaacg gttcgccccg gcgtacgagg cggaactgga cgcgttcctg cgcgtcgtcc
    20341 gcggcgagct ggccaatccg tgcgacgggc gggaggccct gcacgccctg cggatcgccg
    20401 aggcgtgcga ggtctcccgc cgggaacgcc ggccggtcgc gatgagcgag atccccggcg
    20461 gctgaaccgg gaccccggac cggccggccg ctaccaggcg accgggagac tcagcggccc
    20521 ccgcatcagg atcccggtgc gccaggcgag cgtcgccggg tcggcggcca gtcgcaggtc
    20581 cggacagcgt tccagcagcg accggatggc gatcctggcc tcgatgcggg ccagcggcgc
    20641 gcccaggcag tagtggatgc cgtggccgaa ggcgatgtgc ccccgggcgt cgcgggtgat
    20701 gtcgaagcgg gacccgtcgg ggtagcggac ggggtcccgg ttggcgtccg acatcgcgac
    20761 gaggaccagc tcgccgccgc cggggatcat caccccggcg acctcgaccg gatcggtcgt
    20821 gaagcggtag gtgggggtct ccaccggccc ctcgaaccgc aggatctcct cgaccgcgtt
    20881 gtcgatcagc gtgaagtcgg ctcgcagaga cgccagttga tcgggatggg cgagaaggtt
    20941 gtgcacgccg ttggtgatga ggttgacggt ggtctcgtgc ccggcgacca gcaacagcca
    21001 ggccatgccg atcagttcgt cgccggacag ccggtcgccg tcctcgtcgg aggtgtggat
    21061 cagcgcgctc agcaggtcct cgcccggctt ctcgcgcttg tcggcgagca gcccggcgat
    21121 gtacgcggtc atctcctgcg tggaggaggc gcgcagggac gggtcgacgg aggagaccgc
    21181 ctggccggac caggtgcgga aggcctcgcg gtccagggaa gggacgccga gcagctcgca
    21241 gatcaccgac atgggcagcg ggaaggagag cgcctcgacc aggtccgccg tacggtccgg
    21301 ggccgcgagc atcgcgtcca gcaggc
//
