LOCUS       NZ_KZ195572            26576 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. CS057 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195572
VERSION     NZ_KZ195572.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS057
  ORGANISM  Streptomyces sp. CS057
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8333859)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 265.32x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188345.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 02:40:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,152
            CDSs (total)                      :: 7,074
            Genes (coding)                    :: 6,991
            CDSs (with protein)               :: 6,991
            Genes (RNA)                       :: 78
            rRNAs                             :: 10, 6 (16S, 23S)
            complete rRNAs                    :: 10, 6 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 23 of 83
            Pseudo Genes (incomplete)         :: 71 of 83
            Pseudo Genes (internal stop)      :: 4 of 83
            Pseudo Genes (multiple problems)  :: 14 of 83
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:25:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1037324
            Orig. end                         :: 1063900
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195572.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..26576
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26576
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26576
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16576](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16576)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            182..1576
                     /locus_tag="B9W61_RS04145"
                     /old_locus_tag="B9W61_04145"
     CDS             182..1576
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955422.1"
                     /locus_tag="B9W61_RS04145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04145"
                     /product="STM4012 family radical SAM protein"
                     /protein_id="WP_087764205.1"
                     /sec_met_domain="PF04055 (E-value: 1.9e-14, bitscore: 53.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTVAAEAATSGLPSVRPYESYVYAYPHKTAYRPLEDRPSLRSL
                     WAAEPKDALSLYLHIPFCEVRCGFCNLFTRIGAPEELTTRYLDALERQAGAVREALGDE
                     EPVRFAAAAFGGGTPTFLTAGELERLCDIAEQRMGADLRSVPLSVETSPSTATADRLAV
                     LADRGTTRISIGVQSFVAEEARAAVRPQRRADVEAALGRIREARIPVLNIDLIYGIDGQ
                     TERSWLVSLDAALAWRPEELYLYPLYVRPLTGLHRLGAAAGAETEALEQAAWDEQRLRL
                     YAVGRDHLLAHGYEQVSMRMFRRTDAPREQESPEDYACQTDGMIGLGCGARSYTAALHY
                     SFDYAVDMREVRSIIDRFTAAEDFSRAEVGRYVDAGEARRRHLLQSLLQAAGLPVADYR
                     ARFGTDPGADFPAELAEFAARGWLDASAPDGLLRLSPSGLAHSDALGPALFSPGVRAAM
                     AAYERK"
     gene            1584..2507
                     /locus_tag="B9W61_RS04150"
                     /old_locus_tag="B9W61_04150"
     CDS             1584..2507
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378201.1"
                     /locus_tag="B9W61_RS04150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04150"
                     /product="STM4011 family radical SAM protein"
                     /protein_id="WP_087764206.1"
                     /transl_table=11
                     /translation="MDLTILYRGPLASCDYDCPYCPFAKRRDSRAQLTADREALERFTG
                     WAAERTDERLSVLFTPWGEGLVRSWYRRALTELSRLPHIERVAIQTNLSCRTDWLADAD
                     PERIALWCTYHPGQTPYERFLGRCRELSAKGIRYSVGVVGFDEHLDEARRLRAALPEEV
                     YLWVNAAEGHTYTDEEAARWTELDPLFPYSRDPHRSAGLPCRTGESVISVDGDGTVRRC
                     HFVKAELGNLYDGSYRRALGPRACPLAVCDCHIGYVHLESLPLYDVFAGGVLERIPAGH
                     LPGAGTPPDGLVVPGPSRRALPLLEP"
     gene            complement(2514..3341)
                     /locus_tag="B9W61_RS04155"
                     /old_locus_tag="B9W61_04155"
     CDS             complement(2514..3341)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449852.1"
                     /locus_tag="B9W61_RS04155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04155"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_087764207.1"
                     /transl_table=11
                     /translation="MADDSRNNQQHTIGSYAAIGDSFTEGVGDPGPDGTYLGWADRFAV
                     LLADRLPAPDGATGPEDSPHGAFRYANLAVRGRLLDQIVEEQIPRAKELAPDLVSFCAG
                     GNDIIRPGTDPDDLAERFERAVADLSNAVGTVMVTTGFDTRGVPVLRHMRGKIATYNVH
                     LRAIADRYHCPVLDLWSLRSVQDRRAWDDDRLHLSPEGHTRVALRAAQVLGHDVPADPD
                     QPWPPQAQRTPFDERRDNIQWAREYLVPWIGRRLRGESSGDHVEAKRPDLLPL"
     misc_feature    3361..3371
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.67"
                     /tool="antismash"
     misc_feature    complement(3409..3424)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.38"
                     /tool="antismash"
     misc_feature    3423..3436
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.12"
                     /tool="antismash"
     gene            complement(3503..4450)
                     /locus_tag="B9W61_RS04160"
                     /old_locus_tag="B9W61_04160"
     CDS             complement(3503..4450)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128943.1"
                     /locus_tag="B9W61_RS04160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04160"
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_087764208.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKSGPISRGVLAAGTGGAALALPLIGATVANAADQA
                     APAVKPAAASVAAAHTAPAAAPAASKAAPKTYAVVSGDYLAKIAAEHQLKGGWEKLYQD
                     NRSTVGENPSLIHPGMKLTLGAKGSAPAEKSAAPKAAAPKAEPKKADPAPKADTVSADD
                     SEGSGNSAQTGSSEATGSGWSAPLASANVTTQYRASGASWSSGYHTGSDFQAASGTPVL
                     AIGPGTVVSAGNSGSYGNEVVIKHEDGMYSQYAHQSSLNVSVGQTVTGGQQIGLSGSTG
                     NSTGPHLHFEVRTGPSYGSDVDPIAYLRQHGVSV"
     regulatory      complement(4454..4614)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    4628..4642
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.09"
                     /tool="antismash"
     misc_feature    complement(4869..4883)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.37"
                     /tool="antismash"
     misc_feature    complement(4973..4987)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.35"
                     /tool="antismash"
     gene            5058..5870
                     /locus_tag="B9W61_RS04165"
                     /old_locus_tag="B9W61_04165"
     CDS             5058..5870
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964842.1"
                     /locus_tag="B9W61_RS04165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04165"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_087764209.1"
                     /transl_table=11
                     /translation="MTQQVPQVPPTETALTGVRNFRDVGGLPTTDGRRTAFGRLYRSGH
                     LAHATAEDATFLGGLGLHTIFDFRHSADHRLDGYDIELAGVRNVSIPLSDPADGAEFWR
                     LVGDGNIEQLRSVLADGKGVDRMIRMYRATIEDRTAEHSRVLHALAEDSVPALMHCAAG
                     KDRAGLSIAVALLAVDVEVEAIEEDYLKSDDLHRRYAVKRSDASGTGMSPEVMELLDPL
                     FGARPAYLAAAFATIEENWGSTDRYLAEGLKVSPETRERLRERLLDRG"
     gene            complement(5919..6092)
                     /locus_tag="B9W61_RS36285"
     CDS             complement(5919..6092)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955417.1"
                     /locus_tag="B9W61_RS36285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6126 family protein"
                     /protein_id="WP_178798185.1"
                     /transl_table=11
                     /translation="MSDSEHYDPLGPGRRVNEDPQEKRMPRGVIIRLFAYLVAGHVIAG
                     FLYLLFVVAGSK"
     gene            complement(6157..6765)
                     /locus_tag="B9W61_RS04170"
                     /old_locus_tag="B9W61_04170"
     CDS             complement(6157..6765)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955416.1"
                     /locus_tag="B9W61_RS04170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04170"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_047179851.1"
                     /transl_table=11
                     /translation="MNTPDEGVPDELPGVAPRLRDLRRDRGLTLEAAAGRAGLSPAHLS
                     RLETGRRQPSLPMLLGLARIYGTTVSELLGEQPPERDAIVRGGGYEGAEADGWMYRQAG
                     GSGRAMQALRVRVPYGAQGDLVRVHPGEEWLYVLEGRLRVGLGDTVHDLEPGDSAHFDS
                     LTPHRIAAVDRGGAELLFVHTLLQSPAAELCLGNALHAR"
     gene            complement(6840..8237)
                     /locus_tag="B9W61_RS04175"
                     /old_locus_tag="B9W61_04175"
     CDS             complement(6840..8237)
                     /NRPS_PKS="Domain: Aminotran_3 (46-367). E-value: 2.4e-89.
                     Score: 291.6. Matches aSDomain:
                     nrpspksdomains_B9W61_RS04175_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="B9W61_RS04175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04175"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_087764210.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.5e-87, bitscore:
                     292.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDGGSQGFDLARLLAERGAERYDLHARHLNHQLPRMLHTIGFDK
                     VYVRAEGAYFWDAEGNDYLDMLAGFGVMGLGRHHPVVRRALHDVLDARLADLTRFDCQP
                     LPGLLAEKLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCEHAFHGLTTGS
                     LSVNGESGFRDGFAPLLPDTSVPLGDLDALRRELRRGDVAALVVEPIQGKGVHAAPPGY
                     LREAQELLHRHKALLIVDEVQTGLGRTGDFYAYQHEEGVEPDLVCVAKALSGGYVPVGA
                     TLGKDWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLTVMEDEETVANARRTGDLLR
                     ERLAALVGRYELLHEVRGRGLMIGIEFGRPASLRLRSRWTMLQAARKGLFAQMVVVPLL
                     QKHRILTQVSGDHLEVIKLIPPLVIGDAEVDRFVAAFTSVMDDAHSGGGLMWDFGRTLV
                     KQAVANR"
     aSDomain        complement(7137..8099)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W61_RS04175_Aminotran_3.1"
                     /evalue="2.40E-89"
                     /label="B9W61_RS04175_Aminotran_3.1"
                     /locus_tag="B9W61_RS04175"
                     /protein_end="367"
                     /protein_start="46"
                     /score="291.6"
                     /tool="antismash"
                     /translation="YVRAEGAYFWDAEGNDYLDMLAGFGVMGLGRHHPVVRRALHDVLD
                     ARLADLTRFDCQPLPGLLAEKLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVL
                     YCEHAFHGLTTGSLSVNGESGFRDGFAPLLPDTSVPLGDLDALRRELRRGDVAALVVEP
                     IQGKGVHAAPPGYLREAQELLHRHKALLIVDEVQTGLGRTGDFYAYQHEEGVEPDLVCV
                     AKALSGGYVPVGATLGKDWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLTVMEDEE
                     TVANARRTGDLLRERLAALVGRYELLHEVRGRGLMIGIEF"
     gene            complement(8329..9348)
                     /gene="hpnH"
                     /locus_tag="B9W61_RS04180"
                     /old_locus_tag="B9W61_04180"
     CDS             complement(8329..9348)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128938.1"
                     /locus_tag="B9W61_RS04180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04180"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_047179849.1"
                     /sec_met_domain="PF04055 (E-value: 2.6e-16, bitscore: 59.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.7e-08, bitscore: 32.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLLEQKLRKREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVARKKYVF
                     LCTNAMLMRKKLDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAMKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLHVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFAGGNRARWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRQLIEETDWEKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETISSNR"
     gene            complement(9354..10001)
                     /locus_tag="B9W61_RS04185"
                     /old_locus_tag="B9W61_04185"
     CDS             complement(9354..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964847.1"
                     /locus_tag="B9W61_RS04185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04185"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_087764211.1"
                     /transl_table=11
                     /translation="MGDPRGSGAPVTPLLVACALGIEQVALRSGRGAPGPVRVLRTGMG
                     PRAAEAAVARLLGPGGVPDAAVIASGFCAGLAPGMHPGDLVVAEETRDADGTTPCTGTG
                     VLVAALTRAVPGRTVHTGPLTGSDHVVRGSERAALRAGGAIAVDMESAATLRTALCHGP
                     RPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSVLPAFYEWHRSLLLPRR"
     misc_feature    complement(9372..9374)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..12001)
                     /gene="shc"
                     /locus_tag="B9W61_RS04190"
                     /old_locus_tag="B9W61_04190"
     CDS             complement(10001..12001)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964848.1"
                     /locus_tag="B9W61_RS04190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04190"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_087764212.1"
                     /sec_met_domain="T2TS (E-value: 8e-147, bitscore: 488.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGTANPSGATAHDPTDTTIAADDVTVAARRAAERSVE
                     HLLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWN
                     TFYGGPGDLSATIEAYVALRLAGDRPDEPHMARASGWIREQGGIAAARVFTRIWLALFG
                     WWRWDDLPELPPELMFFPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELH
                     TDPDHPNPPRKLAPPASWDGIFQRLDKGLHLYHKVAPRPLRRIAMNLAARWIIERQEND
                     GCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLASLDRFAVRREDGARMVEACQSPVWD
                     TCLATIALADAGLRPDHPALVKAADWMLAEEITRPGDWAVRKPELAPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVRHPDPARLQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNR
                     LPFCDFGEVIDPPSADVTGHVVEMLAVEGLAHHPRTREGIEWLLAEQEACGAWFGRWGV
                     NYVYGTGSVVPALIAAGLPAGHPAIRRAVAWLESVQNDDGGWGEDLRSYQEEKWIGHGE
                     STASQTAWALLALLAADRRDTRPVARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVYGDPFADRADTAEGD"
     misc_feature    complement(12087..12103)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.51"
                     /tool="antismash"
     gene            complement(12111..13214)
                     /locus_tag="B9W61_RS04195"
                     /old_locus_tag="B9W61_04195"
     CDS             complement(12111..13214)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964849.1"
                     /locus_tag="B9W61_RS04195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04195"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_179233709.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-59, bitscore:
                     200.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTGTRGESVTPANPAFDTVADTADVTALLERGRALSAPVLRA
                     AVGRLAPPMDTVAAYHFGWIDADGRPSDGDGGKAVRPALALLSAEAAGAPAEAGVPGAV
                     AVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAYDLLLELGTVE
                     AGRAARRLTTATRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLG
                     GADDRTADTLEAYGYHLGLAFQAVDDLLGIWGDPESTGKQTWSDLRQRKKSLPVVAALA
                     AGGEASERLGELLAADAKSNDFDSFSEEEFAARAALIEEAGGREWTAQEARRQHAVAIE
                     ALHAVDMPHRVREQLTELADFVVVRKR"
     gene            complement(13211..14596)
                     /gene="hpnE"
                     /locus_tag="B9W61_RS04200"
                     /old_locus_tag="B9W61_04200"
     CDS             complement(13211..14596)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378207.1"
                     /locus_tag="B9W61_RS04200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04200"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_047181127.1"
                     /sec_met_domain="DAO (E-value: 1.1e-07, bitscore: 30.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDDSPRPVAVVVGGGLAGVTAALRLADAGLDVTLLEGRPRLGGL
                     AFSFQRGDLTVDNGQHVYLRCCTGYRWFLDRIDATGLAPIQDRLDVPVLDVGRAAGPRL
                     GRLRRTGLPVPLHLAGGLAAYPHLSLAEKASVGRAALALGRLDPADPELDRVDFATWLR
                     GHGQSERTIEALWDLVGVATLNATAPNASMALAAKVFKTGLLSEPGAADIGWATVPLGE
                     LHDTLARKALDTAGVRTELRAKAGSLTRTEDGRWNVETAGERITADTVVLAVPQTETHD
                     LLPEGALDEPDLLLDIENAPILNVHVIYDRKVLRRPFFAAIGSPVQWVFDRTHSSGLTG
                     PGQYLAVSQSAAQDEIDLPVAELRSRYLPELERLLPAARGAGIRDFFVTRERTATFAPA
                     PGVGRLRPGPRTRLPGLQLAGAWTDTGWPATMEGAVRSGADAADAALHGLGRPPGHPLQ
                     EAA"
     gene            complement(14715..15635)
                     /gene="hpnD"
                     /locus_tag="B9W61_RS04205"
                     /old_locus_tag="B9W61_04205"
     CDS             complement(14715..15635)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492033.1"
                     /locus_tag="B9W61_RS04205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04205"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_179233876.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.4e-58, bitscore:
                     197.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 8.8e-71,
                     bitscore: 237.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPPVQAAYSYCEAVTGQQARNFAYGIRLLPYEKRQAMSALYAFS
                     RRVDDIGDGELDQETKRTRLESTRELLERIRKDAVDEDDTDPVAVALADAARRFPLPLG
                     GLDELIDGVLMDVRGATYETWDDLKAYCRCVAGAIGRLSLGVFGTAPGARGAERAAEYA
                     DTLGLALQLTNILRDVREDAANGRTYLPADDLAKFGCSAGFHRTTPPPGSDFAGLIHFE
                     VRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLRGRVSLPGHEK
                     AYVAVRGLSGLDARHISRLTSRGRA"
     misc_feature    15604..15622
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(15665..16576)
                     /gene="hpnC"
                     /locus_tag="B9W61_RS04210"
                     /old_locus_tag="B9W61_04210"
     CDS             complement(15665..16576)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955408.1"
                     /locus_tag="B9W61_RS04210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04210"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_047179845.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.8e-40,
                     bitscore: 137.8, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 1e-36, bitscore:
                     125.3, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTPDTRIGDATLGKAADENFPVAPFFLPRAWRDDLMAVYGFAR
                     LVDDIGDGDLAPGGADARHLGLEPEQSDDRLAMLDAFETDLHRVFATTGEEPHHPLLRA
                     LRPTVRRRTLTPEPFLGLIEANRQDQKIRRYGTYAELAAYCELSANPVGRLVLALTGTA
                     SPERVRRSDAVCTALQIVEHLQDVAEDLERDRIYLPAEDMERFRVAESDLAAPSAGASV
                     RALIAYEAQRASELLNEGPPLVGSVNGRLKLLLAGFVGGGRSALTAISAAGFDVLPGPP
                     KPTKPSLLREVGIVLRRARGER"
     gene            complement(16990..17775)
                     /locus_tag="B9W61_RS04215"
                     /old_locus_tag="B9W61_04215"
     CDS             complement(16990..17775)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964853.1"
                     /locus_tag="B9W61_RS04215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04215"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_050362118.1"
                     /transl_table=11
                     /translation="MAEDNAQGRIPTVIADDVHIVYRVNGTGGGRGSATAALSRMMRRG
                     KGEPRGVRKVHAVRGVSFTAYRGEAIGLIGTNGSGKSTLLRAIAGLLPTESGHVYTDGQ
                     PSLLGVNAALMSDLTGERNVVLGGLAMGMSQDEIRQRYQEIVEFSGINEKGDFITLPMR
                     TYSSGMAARLRFSIAAAKNHDVLMIDEALATGDRKFRVRSEERIRELRKEAGTVFLVSH
                     NNKSIRDTCDRALWLEKGELLMDGPTEEVLKAYERETGK"
     gene            complement(17768..18697)
                     /locus_tag="B9W61_RS04220"
                     /old_locus_tag="B9W61_04220"
     CDS             complement(17768..18697)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="B9W61_RS04220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04220"
                     /product="ABC transporter permease"
                     /protein_id="WP_047179843.1"
                     /transl_table=11
                     /translation="MSDTTHDGGVALGTPPSADEGLDAAQLAAKYGLTVSGARPGLIAY
                     MRQLWGRRHFILAFSRAKLTAQYSQAKLGQLWQVVTPLLNACVYYLIFGLILGTREGIS
                     HDVFVPFLVTGVFVFTFTQSSVMAGVRAISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVLVAVAVIFGSYPSLSWLLVIPALILQFFFNTGLALVMARLGSKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLKDKPAWIADVLQYNPAAIYMDLVRFALIDGYGSENLPDHVW
                     AVGAGWAVLLGVVGFVYFWKAEERYGRG"
     gene            complement(18799..19671)
                     /locus_tag="B9W61_RS04225"
                     /old_locus_tag="B9W61_04225"
     CDS             complement(18799..19671)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513265.1"
                     /locus_tag="B9W61_RS04225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04225"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_178798471.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.5e-10,
                     bitscore: 38.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGAVIITMGNRPDELRALLDSVTAQHGDRIEVVVVGNGAPVPD
                     VPAGVRTVELPENLGIPGGRNVGIEAFGPSGADVDALLFLDDDGLLPNRDTAELCRQAF
                     AADPKLGIVTFRIADPDTGATQRRHVPRLRAADPMRSSRVTTFLGGANAVRTRVIADVG
                     PLPQDFFYAHEETDLAWRALDAGWMIDYRADMVLNHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPAPLVPLYLGVWLLLTLVRRPSAPALKAWFGGFREGWSTPCGPRRPMKWRTVWRL
                     TRLGRPPVI"
     gene            complement(19680..20459)
                     /locus_tag="B9W61_RS04230"
                     /old_locus_tag="B9W61_04230"
     CDS             complement(19680..20459)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="B9W61_RS04230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04230"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_073805270.1"
                     /transl_table=11
                     /translation="MRRPSVAELRPVVHPPGVKDRRSGEHWAGRMYMREISLRVDRYLV
                     NTRVTPNQVTYVMTLAGALAAPALLVPGVWGAVLGVVMVQLYLLFDCVDGELARWKKQY
                     SLSGVYLDRVAAYLCDAAVLVGLGLRAADIWGEGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGMPPVKEAASEPRSSGMALARRAAAALKFHRLILGIEASLVILVVAVVDA
                     IGGDLFYTRLTVAVMAGIALLQTLLHLVSVLASSRLK"
     gene            complement(20437..21498)
                     /locus_tag="B9W61_RS04235"
                     /old_locus_tag="B9W61_04235"
     CDS             complement(20437..21498)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="B9W61_RS04235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04235"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_073805271.1"
                     /sec_met_domain="Fe-ADH (E-value: 3.3e-18, bitscore: 64.3,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 2.5e-09, bitscore:
                     35.3, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGAMDDLAGLLADQRISSSGKLAIAISD
                     GSGRALKERLAPVLPGADWYPVSDGTIDSAVKLADGIKGNRYDAVVGLGGGKIIDVAKY
                     AAARVGLPMVAVATNLSHDGLCSPVATLDNDNGRGSYGVPTPIAVVIDLDVIREAPARY
                     VRSGIGDAISNISCVADWELAHEVNGEEIDGLAAAMARQAGEAVLRHPGGVGDDAFLKV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLFPQRAASHGEQVGLGACFAMHLRG
                     ARQESLLMASILRRHGLPVLPEEIGFSVDEFVKAVDYAPQTRPGRFTILEHLNLSTDQI
                     RDAYADYATTISS"
     gene            complement(21486..22223)
                     /locus_tag="B9W61_RS04240"
                     /old_locus_tag="B9W61_04240"
     CDS             complement(21486..22223)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="B9W61_RS04240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04240"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_073805272.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.6e-11, bitscore:
                     43.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGDKTVLDLTLANFAEV
                     GLTEVAIVVGYRKEAVYARKAELEATYGVTLTLIDNDKAEEWNNAYSLWCARDVIKRGV
                     ILANGDTVHPVSVEKTLLDARGKGQKIILALDTEKVLADEEMKVITEEGKGVQRITKLM
                     DPATATGEYIGVTLIEADAAEELADALKTTFERDPDLYYEDGYQELVNRGFTVDVAPIG
                     TVTWVEIDNHDDLKKGREIACQY"
     gene            complement(22220..23974)
                     /locus_tag="B9W61_RS04245"
                     /old_locus_tag="B9W61_04245"
     CDS             complement(22220..23974)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955402.1"
                     /locus_tag="B9W61_RS04245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04245"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_179233710.1"
                     /transl_table=11
                     /translation="MQTAADAGDAATLLAAVPAGRRVALVDPRFVGHVHALRLGLTDPR
                     FPAATVPGALTAQPEARGALLRALHRTAAAVGAGAPVVEPDADPAPEDRTVPGRIAVAL
                     EAEGTAVQRPALGSLVAAVPTDPEQQAAAEAGLASVDDEAVRLRNAVKAHDGFFTTYCI
                     SPYSRYIARWCARRNLTPNQVTTASLITALIAAGSAATGTRGGYVAAGILLLVSFVLDC
                     TDGQLARYSLQYSTMGAWLDATFDRAKEYAYYAGLAIGAVRGGDDVWVLALGAMVLQAC
                     RHVVDFSFNEANHDAVANTSPTAALSDKLDSVGWTVWARRMIVLPIGERWAMIAVLTAL
                     TTPRIVFYALLVGCSLAACYTTAGRLLRSLTRRAGRTDRAAQALADLADSGPLAQAVAA
                     VAPGLRGAFTAPAVALLGTLVMIGGALFLPYGSPLTVAAAAVYVVLSGLAVARPLKGAL
                     DWLVPPFFRAAEYVTVLVVAARSDVPHAVPAAFGLVSAVAYHHYDTVYRIRGGTGAPPQ
                     WLVRTIGGHEGRTALVVVLAAVLTHTSGFTTALTALAVAVALVVLVESIRFWVSSSAPA
                     VHDEGELA"
     misc_feature    complement(24213..24228)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    24214..24228
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            24349..25338
                     /gene="galE"
                     /locus_tag="B9W61_RS04250"
                     /old_locus_tag="B9W61_04250"
     CDS             24349..25338
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (63-206). E-value:
                     5.2e-10. Score: 30.8. Matches aSDomain:
                     nrpspksdomains_B9W61_RS04250_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612695.1"
                     /locus_tag="B9W61_RS04250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04250"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_087764215.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.7e-19, bitscore:
                     67.6, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.3e-11,
                     bitscore: 42.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMVAAGERVVVLDDRSSGIVERLPDAV
                     TLVEGSASDRALLDRVLADHAVSGVVHLAAKKQVGESVEKPLLYYRENVAGLAVLLEAV
                     VAAGVSRFLFSSSAAVYGVPDVDLITEETPCLPINPYGETKLTGEWLVRAAGKAHGIST
                     ACLRYFNVAGAAAPELADTGVFNIVPMMFERLTRGEAPRIFGDDYPTPDGTCIRDYIHV
                     ADLAEAHLAVARRLDGAGAGDLTLNVGRGEGVSVRELAEVIGKVTGRSPEPVVEARRAG
                     DAPKAVASAARITEELGWTARRGVREMVESAWEGWCLRHPEACAQGRG"
     CDS_motif       24352..24438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9W61_RS04250_0001"
                     /evalue="9.60E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="B9W61_RS04250"
                     /protein_end="30"
                     /protein_start="1"
                     /score="27.9"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMVAAGERVVVL"
     aSDomain        24538..24966
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W61_RS04250_NAD_binding_4.1"
                     /evalue="5.20E-10"
                     /label="B9W61_RS04250_NAD_binding_4.1"
                     /locus_tag="B9W61_RS04250"
                     /protein_end="206"
                     /protein_start="63"
                     /score="30.8"
                     /tool="antismash"
                     /translation="DHAVSGVVHLAAKKQVGESVEKPLLYYRENVAGLAVLLEAVVAAG
                     VSRFLFSSSAAVYGVPDVDLITEETPCLPINPYGETKLTGEWLVRAAGKAHGISTACLR
                     YFNVAGAAAPELADTGVFNIVPMMFERLTRGEAPRIFGD"
     misc_feature    complement(25412..25426)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            25522..26463
                     /locus_tag="B9W61_RS04255"
                     /old_locus_tag="B9W61_04255"
     CDS             25522..26463
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="B9W61_RS04255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W61_04255"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_087764216.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHGGPPPTGTAAAAYRGRLRVALAITLSVMVMEIVG
                     GVLSDSLALIADAAHMATDALGLGMALLAIHFANRPAGPNRTFGFARAEILAALANCVL
                     LLGVGGFLVFEAVERFITPAETKGGLAIAFAAVGLVANVVSLSLLMRGQQESLNVRGAY
                     LEVLADTLGSLAVIVSAGVIMATGWQPADPIASLVIGLMIVPRTVKLLRETLNVLLEAA
                     PKGVDMAEVRAHITELPGVLDVHDLHAWTITSGMPVLSAHVVVRQEVLDSTGHEKVLHE
                     LQGCLGDHFDVEHCTFQLEPSGHAAHEPRLCH"
     misc_feature    complement(26502..26517)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.04"
                     /tool="antismash"
ORIGIN
        1 ggctcttcgc cgcggcgagc agccggcgcc ggtgcttcgc gatcgtctgc tccgaccacg
       61 gcaccgccta cggcgacgac ggctacaccg gtcaccggct cggccacccg gccgtctgga
      121 ccgtcccgta cgcgcacttc ttcctcgaac cacccgcacc gctcgaaccg ggggccgccc
      181 gatgaccacc accgtcgccg cggaagcggc cacctccggg cttccctccg tacggccgta
      241 cgagagttat gtctacgcct atccgcacaa gacggcctac cgtccgctgg aggaccgccc
      301 gtcgctgcgg tcgctgtggg cggcggagcc caaggacgcg ctctccctct atctccacat
      361 accgttctgc gaggtccgct gcggcttctg caacctcttc acccggatcg gcgcgcccga
      421 ggagctgacg acgcgctatc tggacgcgtt ggagaggcag gccggggcgg tgcgggaggc
      481 gctgggcgac gaggagccgg tgcggttcgc cgcggcggcg ttcggcggcg gcacgccgac
      541 cttcctgacc gcgggtgagc tggagcggct ctgcgacata gcggagcagc ggatgggcgc
      601 cgacctgcgc tcggtgccgc tgtcggtgga gacctccccg tccacggcga cggcggaccg
      661 gctggcggtg ctggccgacc ggggcacgac gcggatcagc atcggtgtgc agagtttcgt
      721 ggccgaggag gcgcgggcgg cggtccgccc gcagcgccgc gccgatgtgg aggcggcgct
      781 cggccggatc cgcgaggccc ggatcccggt gctgaacatc gacctgatct atggcatcga
      841 cgggcagacg gagcgcagct ggctcgtctc gctggacgcg gcgctggcct ggcggccgga
      901 ggagttgtat ctgtatccgc tgtacgtccg cccgctcacc ggtctgcacc gcctgggcgc
      961 ggcggccggc gccgagactg aggccctgga gcaggccgcc tgggacgagc agcggctgcg
     1021 gctgtacgcg gtggggcggg accatctgct ggcgcacggc tatgagcagg tgtcgatgcg
     1081 gatgttccgg cggacggatg cgccgaggga gcaggagagt cccgaggact acgcctgcca
     1141 gaccgacggc atgatcggcc tgggctgcgg ggcccgttcg tacacggcgg ccctgcacta
     1201 ctccttcgac tacgcggtgg acatgcggga ggtccggtcg atcatcgacc gcttcaccgc
     1261 cgccgaggac ttctcccggg ccgaggtcgg ccggtacgtc gacgccggcg aagcgcgccg
     1321 acggcatctg ctgcagtcgc tgctccaggc ggcggggctg ccggtggcgg actaccgggc
     1381 acggttcggc acggatccgg gcgcggactt ccccgccgag ctggcggagt tcgcggcccg
     1441 gggctggctg gacgcgtcgg cgccggacgg tctgctcagg ctgtccccgt cgggcctcgc
     1501 ccactccgac gcgctgggtc ccgcgctgtt ctcccccggg gtgcgggccg cgatggccgc
     1561 gtacgagcgg aagtgacggg gcgatggacc tgacgattct ctaccggggc ccgctcgcct
     1621 cctgcgacta cgactgtccg tactgcccct tcgccaagcg gcgggacagt cgcgcgcagc
     1681 tcacggcgga ccgggaggcg ctggagcggt tcaccggctg ggcggccgag cggaccgatg
     1741 aacggctgtc cgtgctgttc actccgtggg gcgagggcct ggtgcgttcc tggtaccggc
     1801 gggcgctgac cgagctgtcg cggctgccgc acatcgagcg ggtcgcgatc cagacgaacc
     1861 tgagctgccg caccgactgg ctggcggacg ccgatccgga gcggatcgcg ctctggtgca
     1921 cgtatcaccc ggggcagacc ccgtacgagc ggttcctggg caggtgccgg gagctgtccg
     1981 cgaaggggat ccgctacagc gtgggcgtgg tggggttcga cgagcatctc gacgaggccc
     2041 ggaggctgcg ggcggcgctg ccggaggagg tctatctctg ggtgaacgcc gccgaggggc
     2101 acacctacac cgacgaggag gcggcgcggt ggacggagct ggatccgctg ttcccctaca
     2161 gccgtgatcc gcaccgctcg gcggggctgc cctgccggac gggcgagtcg gtgatctcgg
     2221 tggacggcga cggcacggtg cggcgctgtc acttcgtcaa ggcggagctg gggaatctgt
     2281 acgacggcag ctaccgccgg gcgctcggcc cgcgggcctg tccgctcgcc gtgtgcgact
     2341 gccacatcgg ttatgtgcat ctggagtcgc tgccgctgta cgacgtgttc gcgggtggtg
     2401 tcctggagcg gataccggca ggacacctgc cgggcgcggg cacgccgccg gacgggctcg
     2461 tggtgccggg cccgtcccgg cgtgcgcttc ccctgctgga gccctgaccg gtcctacagc
     2521 ggcaggaggt ccgggcgttt cgcctcgacg tggtcgcccg aggactctcc gcgcagccga
     2581 cggccgatcc agggcacgag gtattcgcgg gcccactgga tgttgtcgcg ccgctcgtcg
     2641 aagggggtgc gctgggcctg gggcggccag ggctggtcgg ggtcggcggg cacgtcgtgg
     2701 ccgaggacct gtgcggcgcg cagcgcgacg cgggtgtggc cctcgggcga caggtgcagc
     2761 cggtcgtcgt cccacgcgcg ccggtcctgg acggagcgca gcgaccacag gtccagcacg
     2821 gggcagtggt agcggtcggc gatggcccgc agatggacgt tgtacgtggc gatcttgccg
     2881 cgcatgtggc gcagcaccgg aacgccccgg gtgtcgaagc cggtggtgac catgaccgtg
     2941 ccgacggcgt tgctcaggtc ggcgaccgcc cgctcgaagc gctcggcgag gtcgtcgggg
     3001 tcggtgccgg gccggatgat gtcgttgccg cccgcgcaga agctgaccag gtcgggggcc
     3061 agttccttgg cgcgcgggat ctgttcctcg acgatctggt cgaggagacg tcctcgtacg
     3121 gcgagattgg cgtagcggaa ggctccgtgc ggggagtcct cggggccggt cgccccgtcg
     3181 ggggccggga gccggtcggc gaggagcacc gcgaagcggt ccgcccagcc gagatacgtt
     3241 ccgtcggggc cggggtctcc gacgccctcg gtgaaactgt cgccaatcgc cgcgtacgac
     3301 ccgatggtgt gctgctggtt gtttctcgaa tcgtctgcca caagcactta tcctgcatcg
     3361 tgcgatgtga cctacgcgac cgtaatacgg ggttgacggg tggtgagata gaccacccgg
     3421 tcagtttttg gtaaagccgg aataagtgga ggggcggtgc gccgccgcgc accgcccctc
     3481 gattacttct cgccgcgccc ggtcagacgg agacgccgtg ctgacgcagg tacgcgatcg
     3541 ggtcgacgtc cgagccgtag ctcgggccgg tgcggacctc gaagtgcagg tgcggtccgg
     3601 tggagttgcc ggtggagccg gagaggccga tctgctggcc gccggtgacg gtctggccga
     3661 cggagacgtt gagcgaggac tggtgggcgt actgggagta catgccgtcc tcgtgcttga
     3721 tgacgacctc gttgccgtac gagccgctgt tgccggccga gaccacggtg cccggaccga
     3781 tggcgagcac gggggtgccg gaggcggcct ggaagtccga gccggtgtgg tagccgctgg
     3841 accagctggc accggaagcc cggtactggg tggtgacgtt ggcgctggcc agcggggcgg
     3901 accagccgga gccggtggcc tcggaggagc cggtctgcgc cgagttgccg gagccctcgg
     3961 agtcgtcggc ggagacggtg tccgccttcg gcgcggggtc ggccttcttc ggctcggcct
     4021 tcggagcagc ggccttcgga gcggcggact tctcggccgg tgcggagccc ttggcgccga
     4081 gggtcagctt catgcccggg tggatcaggc tggggttctc gccgacggtg gagcggttgt
     4141 cctggtacag cttctcccac ccgcccttga gctggtgctc ggcggcgatc ttcgccaggt
     4201 agtcgccgga gacgacggcg tacgtcttcg gggcggcctt cgacgcggcg ggggcggcgg
     4261 ccggagcggt gtgggcggcg gcgaccgagg cggccgcggg cttcacggcc ggagcggcct
     4321 ggtccgcggc gttcgcgacg gtggcgccga tgagcgggag ggcgagtgcg gcgccaccgg
     4381 tccccgcggc gaggacgccg cgggagatcg ggccggactt cggacgacgg tgcttaccct
     4441 ttgcgggcat ggggaatttc ctctccggcg cctgcgaggt gagctgtcgg gttcgggctg
     4501 gagatgcccg gtcgccttgc ggcgacttca ccccgagccg gtccggatct ctccggatcg
     4561 gcggcttacc tggttccccc gctcctgcca cacgtgagtg ggtgggtgcg aattccgggc
     4621 ggcggcagga ttaggcggtc cgtccggatt gcggcgaccg taaacgagtc aggacgagca
     4681 gaacaagcca tcggttgcgc acccgaaaca tcgattcggt ttcgctccgg aattcccgtc
     4741 acactccgtg gattacggat cttggatttc cgtacgggta acgggaatgg cccggggcgc
     4801 gcccgccacg gaccgtcaca gatatgatcc cgctcacctc cgaaatccca tctcccccat
     4861 tagcggggca tgttctgcga aatgcaccaa tacggacacg gcccgggcgc cgcccctgac
     4921 gccaggtcag cccggccgcc ccggcaccct caccgaggtg agcgaccgtg atgattttcc
     4981 gacgaatcga tgtcgtatcg tcacgggagc gccctcgccg gcgagccgcg ccgacgccag
     5041 agatcccagg agccaccgtg acgcaacagg tgccgcaggt cccgccgaca gagaccgcgc
     5101 tgaccggagt ccgcaacttc cgcgacgtgg gcgggctccc caccacggac gggcggcgca
     5161 ccgccttcgg gcggctctac cggagcggcc acctggcaca cgcgaccgcc gaggacgcga
     5221 ccttcctcgg cgggctcggg ctgcacacga tcttcgactt ccgacactcc gcggaccacc
     5281 ggctcgacgg atacgacatc gaactggccg gtgtccgcaa tgtcagcatt ccgctctcgg
     5341 acccggccga cggcgcggag ttctggcgac tggtgggcga cgggaacatc gagcagctgc
     5401 gctcggtcct cgcggacggc aagggcgtcg accgcatgat ccggatgtac cgcgcgacga
     5461 tcgaggaccg caccgccgag cacagccggg tgctgcacgc cctggccgag gacagcgtcc
     5521 ccgcactgat gcactgcgcg gcgggcaagg accgggccgg actctcgatc gcggtcgccc
     5581 tgctggcggt cgacgtcgag gtggaggcga tcgaggagga ctacctcaag tccgacgacc
     5641 tccaccgccg ctacgccgtg aagcgctccg acgcgtccgg gacggggatg tcgcccgagg
     5701 tgatggagct gctggacccg ctcttcgggg cgcggcccgc ctacctggcg gcggccttcg
     5761 cgaccatcga ggagaactgg ggatcgacgg accgctacct ggccgagggg ctgaaggtct
     5821 ctcccgagac ccgggagcgg ctgcgcgagc gcctgctcga ccggggctga cccggagggc
     5881 ggcggtccgt ccgcgggcgg acggccgtcc gcccgccgtc acttgcttcc ggccaccacg
     5941 aagagcaggt agaggaagcc cgcgatgacg tggcccgcca cgagataggc gaagagccgg
     6001 atgatgacac cccgcggcat ccgcttctcc tgcgggtcct cgttcacgcg gcgaccggga
     6061 cccagcgggt catagtgttc ggaatcagac atgacggtcc tctctgtcgg cctggcggcc
     6121 ggtggagcga aggatgggtc cggcggggac ggccggtcag cgcgcgtgga gggcgttgcc
     6181 gaggcacagc tcggcggcgg gactctgcag cagggtgtgg acgaagagca gctccgcacc
     6241 gccgcggtcg acggccgcga tccggtgcgg ggtgagcgag tcgaagtggg cgctgtcgcc
     6301 gggttcgagg tcgtggacgg tgtcgccgag cccgacccgc agccgccctt ccaggacgta
     6361 cagccactcc tcgccgggat ggacccggac caggtcgccc tgggccccgt acggaacgcg
     6421 cacccgcagc gcctgcatcg cgcggccgga tccgcccgcc tgccggtaca tccagccgtc
     6481 ggcctccgcc ccctcgtagc cgccaccgcg gacgatcgcg tcacgttcgg gcggctgctc
     6541 gccgagcagc tcggagaccg tcgtaccgta gatacgggcg agccccagca gcatcggcag
     6601 cgagggctgc ctgcggccgg tctccagccg ggagagatgg gccggggaga gtccggcccg
     6661 gccggcggcg gcctccaggg tgagaccgcg gtcgcggcgc aggtcccgca gtcggggtgc
     6721 gacgccgggg agctcgtccg gcaccccttc gtccggagtg ttcatgcctc cattgggcca
     6781 ggatatttcc tctgaggcaa ataacttacc tcagaggcaa ttcccgtccc ccgctccggt
     6841 cagcggttgg ccacggcctg cttgaccagc gtccggccga agtcccacat cagtccgccg
     6901 ccgctgtgcg cgtcgtccat gacggacgtg aaggccgcca cgaagcggtc cacctccgcg
     6961 tccccgatga ccagcggcgg aatcagtttg atcacttcca ggtggtcgcc ggagacctgg
     7021 gtgaggatcc ggtgcttctg gagcagcggc accacgacca tctgggcgaa gagacccttg
     7081 cgggccgcct gcagcatggt ccagcggctc cggagcctga gcgaggcggg cctgccgaat
     7141 tcgatgccga tcatcagccc gcgcccgcgg acctcgtgga gcagttcgta gcggcccacc
     7201 agggccgcca gccgctcgcg cagcaggtca ccggtgcgcc gggcgttcgc gacggtctcc
     7261 tcgtcctcca tcaccgtcag gacggcgagg cccgccgcca tcgcctgggc gttggagccg
     7321 aagctcgcgg agtggacgag gacccggtcc atcgaggagt agaccttgcg gaagatccag
     7381 tccttgccga gggtcgcgcc gaccggcaca tagccgccgg agagcgcctt ggcgacgcac
     7441 acgaggtcgg gctcgacccc ctcctcgtgc tggtaggcgt agaagtcccc ggtccggccg
     7501 agacccgtct gcacctcgtc gacgatcagg agcgccttgt gccggtgcag cagctcctgg
     7561 gcctcgcgca gatagccggg gggcgcggcg tgcacgcctt tgccctggat gggctccacg
     7621 accagggccg cgacgtcgcc ccgcctcagc tcgcggcgca gcgcgtccag gtcgcccagt
     7681 gggaccgatg tgtccggcag cagcggggcg aagccgtcgc ggaagccgct ctccccgttg
     7741 accgacaggg atcccgtggt gagcccgtgg aaggcgtgct cgcagtagag gacccggggc
     7801 ttcccggtgg catagcgggc gaacttcagc gccgtctcga ccgcctccgt gccgctgttc
     7861 ccgaagaaga cgcggtccag gtgcgggctg tgggcgagga gcttctcggc gagcagtccg
     7921 ggcagcggct ggcagtcgaa gcgggtgagg tcggcgagcc gggcgtccag gacgtcgtgc
     7981 agggcccggc ggacgacggg gtggtggcgg ccgaggccca tgacaccgaa cccggcgagc
     8041 atgtcgaggt agtcgttgcc ctccgcgtcc cagaagtacg cgccctcggc ccgcacgtag
     8101 accttgtcga agccgatggt gtgcagcatg cgcggcaact ggtggttgag gtggcgcgcg
     8161 tgcaggtcgt accgctcggc cccgcgctcg gcgaggagcc gagccaggtc gaagccctgg
     8221 gatccgccgt ccgtcatcgc ccgtccttct ccttcgaggt gtgctgctgc ggagggccgg
     8281 ccgccccggg gacccgaggc ggccggccgt accccgtcgg tcaccgcctc accggttgct
     8341 gctgatggtc tcccgtgccg cgcgcaggga ctccttcagg gaccccatgg tggcgagcac
     8401 cgccgtgggc tcgtagccgc agtgcgccat gcagttggcg cagcgcgggt ccttgccccg
     8461 gccgtacttc tcccagtcgg tctcctcgat gagctggcgg tacgtcggta cgtaaccgtc
     8521 gctcatcagg tagcaggggc gctgccagcc gaagagggag tagttgggga tcgcccacgc
     8581 ggtgcacggg aagtccgcct tgccctccag gaagtccagg aagagcggcg agtggttgag
     8641 ccgccagcgg gccctgttgc cgcccgcgaa ggccttcttg aacagctcgc gggtctgctc
     8701 gacgccgagg aagtgctcct ggtcgggggc cttctcgtag gcgtaggcgg gcgagatcat
     8761 catctcgtcg acgtgcaggt cgtcgttgag gtagttgagc acctcgatga tggtctgcgg
     8821 ggtgtcggtg ttgaagaagg tggagttggt ggtgacgcgg aagccgcgcc gcttggcctc
     8881 cttcatcgcg gcgacggcct cgtcgaagac gccttccttg gcgaccgact cgtcgtgccg
     8941 ctcgcgcagc ccgtcgatgt gcacggcgaa ggcgaagtac ggggacgggg tgaacttgtc
     9001 gagcttcttc cgcatcagca tggcgttggt gcagaggaag acgtacttct tcctcgcgac
     9061 gagctgacgc acgatctcgt cgatctgggg gtgcatcagt ggttcgccac ccgcgatgga
     9121 caccatgggg gcgccggatt cgagcaccgc gcccaccgcc tgggcgaccg gcatgcgctg
     9181 cttcaggaca ccggccgggt gctggatctt cccacagccc tcgcaggcga ggttgcaggc
     9241 gaacaacggc tccagctcga cgatcagcgg gaacttctca cgcttgcgga gcttctgttc
     9301 gaggagatac gtcgcaacct tgatggactg acggagcggc atggccatct ggctcacctc
     9361 ctggggagca gtaaagatcg gtgccattcg tagaaagccg gaaggacgga acgaagaacg
     9421 cggaacgccg atattccacc gcgtacggtg ccgatacgga cgagctcatg ctctggagcg
     9481 tccacgacca cccggacggc cgcaaccggg cgtggcccgt ggcacagggc ggtacgcagt
     9541 gtcgcggcgg actccatgtc caccgcgatg gccccgccgg cccgcagcgc ggcccgttcg
     9601 gagccccgta cgacgtggtc ggagccggtc agcgggccgg tgtggaccgt acggcccgga
     9661 acggccctgg tgagcgcggc gaccaggacg ccggtgcccg tgcagggcgt ggtgccgtcc
     9721 gcgtcccggg tctcctcggc gacgaccagg tccccggggt gcattcccgg ggcgaggccg
     9781 gcgcagaagc cggaggcgat gacggcggcg tcggggaccc cgccggggcc caggaggcgc
     9841 gccacggccg cctccgccgc ccggggcccc attccggtgc gcagcacccg gaccggtccc
     9901 ggggcgcctc tgccgctgcg cagggccacc tgctcgatgc ccagagcgca ggcgaccagc
     9961 aggggcgtca cgggggctcc ggaccctctc ggatcgccca tcagtccccc tcggcggtgt
    10021 ccgcgcggtc ggcgaacggg tcgccgtaca catagcgccc gagtgcggtg agcgggaaga
    10081 cctggcggta gaggtggtag ttgatggaga agtcccaggg gaagccggtg ccggtgaagt
    10141 acggctcgtc ccaggagccg tcggcctgct gcgcctcggt cagccaggtg acgccccggg
    10201 ccaccgggcg ggtgtcccgg cggtccgcgg ccaggagggc cagcagcgcc caggcggtct
    10261 gggaggccgt ggactcaccg tgcccgatcc acttctcctc ctggtaggag cgcaggtcct
    10321 cgccccagcc gccgtcgtcg ttctgcacgg actccagcca ggcgacggcc cggcggatcg
    10381 cggggtgtcc ggcgggcagc ccggcggcga tcagggcggg caccacggac ccggttccgt
    10441 agacgtagtt gacgccccag cggccgaacc aggccccgca cgcctcctgt tcggcgagca
    10501 gccactcgat gccctcgcgg gtacgggggt ggtgggcgag cccttcgacg gcgagcatct
    10561 ccacgacatg gccggtgacg tcggccgacg gcgggtcgat gacctcgccg aagtcgcaga
    10621 agggcagacg gttggggaag gggctggtgt tgtcggcgtc gaacgcgccc caggccccgt
    10681 tgcgggactg catcccgagg ttccagcgga ccccccggtc gatggccgcc tgcaggcggg
    10741 cgggatcggg gtggcgcacc cggcgcagcg ccaggacgac ctcggcggtg tcgtcgatgt
    10801 ccgggtagtt gtcgttgtgg aactcgaacg cccagcctcc cggggcgagt tccggctttc
    10861 gcaccgccca gtcacctggt ctggtgatct cctcggcgag catccagtcg gcggccttca
    10921 ccagggccgg gtggtcgggt ctgagtccgg cgtcggccag tgcgatggtg gccagacagg
    10981 tgtcccagac gggcgactgg caggcttcca ccatgcgggc gccgtcctcg cgccggacgg
    11041 cgaaccggtc gagcgaggcc aggcccgccc tcatcaccgg gtggtcgagg tcgtagccga
    11101 gcaggtgcag agcgatgacg gagtagacgg cgggcggctg gatcccgccc cagcagccgt
    11161 cgttctcctg gcgctcgatg atccaccggg cggccaggtt catcgcgata cggcgcagtg
    11221 ggcgcggggc gaccttgtgg tagaggtgca gccctttgtc gaggcgctgg aagatcccgt
    11281 cccaactggc gggcggggca agcttcctgg gcgggttggg gtggtcgggg tcggtgtgca
    11341 gctcgtccag ggcgaagggt gcggggcgca ccgggcgctt ggcggagacg acggtgaggg
    11401 gcacgatggt ctgccgggcc cagcagccga agtcgtagat gttgagcggg acccacttgg
    11461 ggaagaacat cagctcgggc ggcagttcgg ggaggtcgtc ccacctccac cagccgaaca
    11521 gggccagcca gatacgggtg aagacgcggg cggccgcgat gccgccctgt tccctgatcc
    11581 agccggaggc gcgtgccatg tgcggttcgt cggggcggtc cccggccagc cgcagggcga
    11641 cgtacgcctc gatcgtggcg gagaggtcac ccggcccgcc gtagaaggtg ttccaggtgc
    11701 cgtcgccgag ctgttcgccg cggatgaaga gggcggccgc ccgggtggtc tcggggtcct
    11761 ggataccgag gaactgacgc aggagcaggt cttccgcgtc catcgtgacg ttggtggcga
    11821 ggtcgccctt ccaccagccc tgctcgtcct gtctgccgag gaggtgctcc accgagcgtt
    11881 ccgcggcccg tcgcgcggcg acggtcacgt cgtccgcggc gattgtcgtg tcggtcggat
    11941 cgtgggccgt ggccccggag gggttcgcgg tcccggtcga tccgtcggtc gtcgctgtca
    12001 tgagcttccc cttacgtgca gtcggttctc tgctgtgctg gggtcaccgt cggccgacgc
    12061 ccggtcaagg gggcgccggc cggcgactgc gagtcatatg cgaagagtga tcatctcttt
    12121 cgaaccacca cgaagtcggc gagctcggtg agctgctccc tcacccggtg gggcatgtcg
    12181 acggcgtgca gcgcctcgat ggcgaccgcg tgctgacgac gggcttcctg ggcggtccac
    12241 tctcggccgc ccgcctcctc gatgagcgcc gcacgggcgg cgaactcctc ttcggagaag
    12301 ctgtcgaagt cattgctctt ggcgtcggcg gcgagcagtt cgcccagcct ctcggaggcc
    12361 tcgccgcccg cggcgagcgc cgcgacgacg ggcagggact tcttgcgctg gcgcaggtcg
    12421 ctccaggtct gcttgccggt ggactccggg tcgccccaga tgccgaggag gtcgtcgacg
    12481 gcctggaagg cgaggccgag gtggtagccg tacgcctcca gggtgtcggc ggtacggtcg
    12541 tcggcgccgc cgagcaccgc gccgatggag acggcgcagg ccagcagggc gccggtcttg
    12601 ttgccctcca tctccaggca ctcctcgacg gtgacccgct cccggtgctc gtaggagatg
    12661 tcctgggcct gcccgtcgat gagcttgcgg gtggcggtgg tcagccggcg ggccgcgcgg
    12721 cccgcctcga ccgtgccgag ctccagcagc aggtcgtagg cgagcgcgaa gagcgcgtcg
    12781 ccgaccagga tcgcctgggc cgggccgtgc accttccata cggtgtcgcg gtggcggcgc
    12841 tgctcgtcgc cgtccatcag gtcgtcgtgc agcagcgaga agttgtgcac gagttcgacg
    12901 gccaccgcgc cggggacgcc cgcctcggcg ggcgcgcccg ccgcctctgc ggacagcagg
    12961 gcgagcgcgg ggcgcacggc cttgccgccg tcaccgtccg aaggccgccc gtcggcgtcg
    13021 atccagccga agtggtacgc ggcgacggtg tccatgggcg gcgcgagccg gcccacggca
    13081 gcccgcagga ccggcgctga cagggctcgt ccgcgctcca gaagcgcggt gacgtccgcg
    13141 gtgtccgcca cggtgtcgaa agccggattc gccggggtca cagactctcc tcttgttccg
    13201 gtggtactgc tcatgccgcc tcctgcagcg gatgtcctgg ggggcggccg aggccgtgga
    13261 gcgccgcgtc ggccgcgtcg gcgccgctgc gcacggcacc ctccatcgtc gcgggccagc
    13321 cggtgtcggt ccaggccccc gcaagctgga ggccgggcag ccgggtgcgg gggccggggc
    13381 gcagccgccc gacgcccggg gcgggcgcga aggtggcggt gcgctcccgg gtgacgaaga
    13441 agtcccggat gcccgcgccg cgggccgcgg ggagcagccg ttccagctcg ggcaggtagc
    13501 gggagcgcag ttcggcgacg gggaggtcga tctcgtcctg cgcggccgac tgcgagacgg
    13561 ccaggtactg cccggggccg gtgaggcccg aggagtgggt gcggtcgaag acccactgga
    13621 ccggggagcc gatcgcggcg aagaacggcc tgcgcagcac cttgcggtcg tagatcacgt
    13681 gcacgttcag gatgggtgcg ttctcgatgt cgagcagcag gtccggttcg tccagcgcgc
    13741 cctcgggcag caggtcgtgg gtctcggtct gcggcacggc cagcacgacg gtgtcggccg
    13801 tgatccgctc ccccgccgtc tcgacgttcc aacggccgtc ctcggtgcgg gtgagggagc
    13861 cggccttggc ccgcagttcg gtgcggacgc ccgcggtgtc cagtgccttg cgggcgaggg
    13921 tgtcgtgcag ttcgccgagc ggcacggtgg cccagccgat gtcggcggcg ccgggctcgg
    13981 agagcaggcc ggtcttgaag accttcgccg cgagcgccat ggaggcgttc ggggcggtgg
    14041 cgttcagggt ggcgacgccg acgaggtccc agagggcttc gatcgtgcgc tccgactggc
    14101 cgtgcccacg cagccaggtg gcgaagtcga cgcggtcgag ctcggggtcg gcggggtcca
    14161 ggcggccgag cgcgagggcg gcgcggccca cgctcgcctt ctcggcgagc gagaggtggg
    14221 gataggcggc gagtccgccg gcgaggtgca gcggtacggg caggccggtg cgcctcagcc
    14281 gtcccaggcg cggtcccgcg gcccggccga cgtcgagcac gggcacgtcc aggcggtcct
    14341 ggatcggggc gaggccggtg gcgtcgatcc ggtcgaggaa ccagcggtag ccggtgcagc
    14401 agcgcaggta gacgtgctgg ccgttgtcga cggtgaggtc gccgcgctgg aaggagaagg
    14461 cgaggccgcc gaggcggggc cgcccttcca ggagggtcac gtcgagtccg gcgtcggcga
    14521 ggcggagcgc cgccgtgacg ccggcgaggc cgccgccgac gacgacggcg acgggacgcg
    14581 ggctgtcgtc gttcatgcgt gcccctctcg cctggtcggt gcgcatcgcc gggtcctcac
    14641 cctggagatc gtcgcagtct gtgacgcgtc gggccactgg agggttgccc aggagccgaa
    14701 gccgccggaa cgcatcaggc ccgccccctg gaggtgagcc gggagatgtg gcgggcgtcc
    14761 agcccggaca ggccgcgcac cgcgacgtac gccttctcgt gtccgggcag cgagacccgt
    14821 ccgcgcagca cggcctcggg gtcgcgctcg atccggtcga ggaggcggcg gtagatcccg
    14881 gccatcgccg cgacgcaggc gccgctgcgg cggtcgagca tcggcagcag ccggtagccc
    14941 tcggcgaaca gggcgcgggc gcggcggacc tcgaagtgga tgaggcccgc gaagtcggag
    15001 ccggggggcg gggtggtccg gtggaaccct gccgagcagc cgaatttggc caggtcgtcg
    15061 gcgggcaggt aggtgcgccc gttggcggcg tcctcgcgga cgtcgcgcag gatgttggtg
    15121 agctggaggg cgaggccgag ggtgtcggcg tactccgcgg cgcgctcggc ccctcgggcg
    15181 ccgggcgcgg tgccgaagac gccgaggctg aggcggccga tggctccggc gacgcaccgg
    15241 cagtaggcct tcaggtcgtc ccaggtctcg taggtcgcgc cccggacgtc catcaggacg
    15301 ccgtcgatca gctcgtcgag cccgccgagc ggaagcggga accggcgggc ggcgtcggcg
    15361 agcgcgacgg ccaccgggtc ggtgtcgtcc tcgtcgaccg cgtccttgcg gatccgctcc
    15421 agcagttcgc gggtgctctc cagccgggtc cgcttggtct cctggtccag ctccccgtcg
    15481 ccgatgtcgt cgacgcgacg ggagaaggcg tacagcgccg acatggcctg ccgcttctcg
    15541 tacggcagca gtctgatgcc gtaggcgaag ttacgggcct gctgtccggt gacggcctcg
    15601 cagtaactgt atgcggcctg caccggcggc gacatgtacg tcgtctgtcc ctccacggtc
    15661 cggctcacct ctctccacgc gctcttcgca agacgattcc cacttcgcgc agcaggctgg
    15721 gcttggtggg cttgggcggt ccgggcagta cgtcgaaccc ggcggccgag atcgccgtga
    15781 gcgcgctgcg accgcccccg acgaatccgg ccaggagcag cttgagcctg ccgttgacgc
    15841 tacccaccag cggggggcct tcattcagca gctcgctcgc gcgctgggcc tcgtacgcga
    15901 tcagggcgcg caccgaggct ccggcggagg gcgcggccag gtcggattcg gcgacccgga
    15961 agcgctccat gtcctcggcg ggcagataga tccggtcgcg ttccaggtcc tcggccacgt
    16021 cctgcagatg ctcgacgatc tggagcgcgg tgcagaccgc gtcggagcgg cggacgcgct
    16081 ccgggctcgc ggtgccggtg agggcgagga ccaggcggcc gaccgggttc gccgagagct
    16141 cgcagtaggc ggcgagctcg gcgtaggtgc cgtagcggcg gatcttctgg tcctggcggt
    16201 tggcctcgat caggccgagg aagggctcgg gggtgagtgt gcggcgccgc accgtggggc
    16261 gcagagcgcg cagcagcggg tggtgcggct cctcgccggt ggtggcgaag acccggtgca
    16321 ggtcggtctc gaaggcgtcg agcatggcga ggcggtcgtc gctctgttcc ggctccaggc
    16381 cgaggtggcg ggcgtcggcg ccgccggggg cgaggtcgcc gtcgccgatg tcgtcgacga
    16441 gccgggcgaa gccgtagacc gccatcaggt cgtcgcgcca ggcgcggggc aggaagaagg
    16501 gcgccacggg gaaattctcg tccgcggcct tgcccagggt ggcgtcaccg atgcgcgtgt
    16561 cgggggtcga ggtcactgcg gaccgcccgg cgcggggacg gcgaaaccac gccggagctg
    16621 gagatcttcc gtcattgccg tcacatctcc cgttctacac tgctgatcca aaacaaccct
    16681 tttcggacac gccgctcagc cttccgagtg cactgcggca gagcggccgg tgccggggct
    16741 tatcgcccta cttgccatga atcagcacca ctacagctta cgttgtacag ctcacaggag
    16801 atcggcgggg tggaacgccc gccgccgttt cccggccatg cccgtcaacc ttccccgcgc
    16861 gcggcggaat tgacgtcatc cgccgggagg agatcgtccc tggggcctac tgcggacggt
    16921 ccgcacggcg ccgcacaccg cacggccccc gccggaccgg tccggcgggg gccacggaga
    16981 accttcgggc tacttgcccg tttcgcgctc gtacgccttg aggacttcct cggtgggacc
    17041 gtccatcagg agttcgccct tctccagcca cagcgcgcgg tcgcaggtgt ccctgatcga
    17101 cttgttgttg tggctgacca ggaagacggt gcccgcctcc ttgcgcagct cgcgaatccg
    17161 ctcctccgag cggacccgga acttgcggtc accggtggcc agcgcctcgt cgatcatgag
    17221 gacgtcgtgg ttcttggcgg cggcgatcga gaagcgcagc cgcgccgcca tgccggagga
    17281 gtacgtccgc atcggcaggg tgatgaagtc gcccttctcg ttgatgccgg agaattccac
    17341 gatctcctgg tagcgctgac ggatctcgtc ctggctcatg cccatcgcca gcccgccgag
    17401 cacgacgttg cgctcaccgg tcagatcgct catcagcgcg gcgttcacgc cgagcagcga
    17461 gggctgaccg tccgtgtaca cgtggcctga ttcggtgggc agcaggccgg cgatggcgcg
    17521 cagcaacgtc gacttgccgg agccgttggt gccgatgaga ccgatggcct cgccccggta
    17581 ggcggtgaag gagacaccgc gcacggcgtg caccttccgg acgccccgcg gttcgccctt
    17641 gccccgccgc atcatgcggc tcagcgcggc ggtggcgctg ccccgtccgc cgcccgtgcc
    17701 gttgacccgg tacacgatgt gcacgtcgtc ggcgatcacc gtggggatgc gcccctgtgc
    17761 gttgtcctca gccacggccg taccgttcct ctgccttcca gaagtacacg aatcccacga
    17821 cgcccagcag cacggcccag cccgcaccga cggcccagac gtggtccggc aggttctcgg
    17881 agccgtatcc gtcgatcagg gcgaagcgga ccaggtccat gtagatcgcc gccgggttgt
    17941 actgcagcac gtccgcgatc caggccggct tgtccttgag catcaccggg atggagaaca
    18001 tgacgcccga ggcgtacatc caggtccgca tgacgaacgg catcagctgc gcgaggtcgg
    18061 gggtcttgga gccgagccgg gccatgacga gggccaggcc cgtgttgaag aagaactgga
    18121 gaatcagggc ggggatcacc aacagccagg acagcgaggg gtagctgccg aagatgacgg
    18181 cgaccgcgac cagcacgatc atcgagaaca gcagctgctg gagctgctgg agcgagaagg
    18241 agatgggcag cgaggcccgg gggaagtgga gggcccggac cagtccgagg ttgccggaga
    18301 tcgcgcggac gcccgccatc accgagctct gggtgaaggt gaagacgaag acgccggtga
    18361 ccaggaacgg cacgaagacg tcgtgggaaa tcccctccct ggttcccagg atcagcccga
    18421 agatcaggta atagacacag gcgttcagca aaggtgtgac cacttgccac agctggccca
    18481 gtttggcctg gctgtactgc gcggtcagct tcgcccggga gaaagccagg atgaagtggc
    18541 gtcgtcccca gagctgtcgc atgtacgcga tcagccccgg cctggcgccg ctcacggtca
    18601 ggccgtactt ggcggccagc tgggccgcgt cgaggccctc gtcggcggac ggcggggtcc
    18661 cgagggctac cccaccgtcg tgggtcgtgt cactcacaag ttgaaactct cgtcttcacg
    18721 cgcagccagt cgcgggcgcg gctcaggcgg acaggttccg gaaagaaaat acgcctcatg
    18781 ctctcagagg aaagcctctc agatgaccgg aggtcggccc agcctcgtca gccgccacac
    18841 cgtacgccac ttcatcgggc gccgaggccc gcagggggtc gaccagcctt cccggaatcc
    18901 gccgaaccat gccttcagcg cgggcgccga aggacgtctc accagggtca gcagcagcca
    18961 gacgcccaga tagagcggga ccagtggggc gggcaggttc cggcgggcga gccagacccg
    19021 gttgcgggcg accatgcggt ggtagaccgc gtgccgggac ggggcggtgg tggggtggtt
    19081 cagcaccatg tccgcgcggt agtcgatcat ccaccccgcg tccagcgccc gccaggccag
    19141 gtccgtctcc tcgtgggcgt agaagaagtc ctgcggcagc ggacccacgt cggcgatgac
    19201 ccgggtgcgt acggcgttgg cgccgcccag gaacgtggtc acgcgcgagg agcgcatcgg
    19261 gtcggcggcc cgcagccggg gcacgtgccg ccgctgggtg gcgccggtgt ccggatcggc
    19321 gatccggaag gtgacgatcc ccagcttcgg gtccgccgcg aacgcctgtc ggcacagctc
    19381 ggcggtgtcc cggttcggga gcaacccgtc gtcgtccagg aagagcagcg cgtccacgtc
    19441 ggcgccggag gggccgaacg cctcgatgcc gacgttgcgg ccgccgggga tgcccaggtt
    19501 ctcgggcagt tccaccgtcc gcacccccgc gggcacatcg gggaccgggg ctccgttgcc
    19561 gaccaccacg acctcgatcc ggtcaccgtg ctgggcggtg accgaatcga ggagggcgcg
    19621 gagctcgtcc gggcggttgc ccatggtgat gatcaccgcg cccagtttca tgggaggggt
    19681 cacttcagcc tgctggacgc caggacggac accaggtgca gcagggtctg cagcagcgcg
    19741 atgccggcca tgaccgccac ggtcaggcgg gtgtagaaga ggtcgccccc gatcgcgtcg
    19801 acgacggcca ccacgaggat caccagcgag gcctcgatgc cgaggatcag ccggtggaac
    19861 ttgagcgcgg cggcggccct gcgggccagc gccatgcccg aggagcgcgg ctcggacgcc
    19921 gcctccttca ccggcggcat cccgccctgg tggcgggcca cgccgaccag gtccgtctcg
    19981 gccttgatga ggatcgcgcc cagcgcggcg agcgtcccga ggaacgccca gagccagtcg
    20041 atccggccct cgccccagat gtcggcggcg cgcaggccga ggccgacgag caccgccgcg
    20101 tcgcacagat aggcggcgac ccggtccagg tagaccccgc tgagcgagta ctgcttcttc
    20161 cagcgggcca gctcgccgtc cacgcagtcg aacagcagat agagctggac catcaccacg
    20221 ccgagcacgg cgccccagac gcccggcacc agcagcgccg gggcggccag cgcgccggcc
    20281 agcgtcatca cgtacgtgac ctggttcggc gtgacgcggg tgttgaccag gtagcggtcc
    20341 acgcgcagcg agatctcgcg catgtacatg cgcccggccc agtgctcgcc gctgcgccgg
    20401 tccttcacgc ccggggggtg aacgaccgga cggagttcag ctactgatgg tcgtcgcata
    20461 gtcggcgtac gcgtccctga tctggtcggt ggacaggttg aggtgctcca ggatcgtgaa
    20521 gcgtcccgga cgcgtctgcg gcgcgtagtc gacggccttc acgaactcgt cgacgctgaa
    20581 cccgatctcc tccggcagga ccggcagacc gtggcggcgc agtatcgatg ccatcaggag
    20641 ggactcctgg cgggcaccgc gcagatgcat ggcgaagcag gcgccgaggc cgacctgctc
    20701 gccgtggctg gccgcgcgct gggggaacag caggtcgaag gcgtggttga tctcgtggca
    20761 ggcgccggag gccgggcggg agtcccccgc gaccgacatc gagatgccgg tcagcacgag
    20821 cccctcggcc agcaccttca ggaaggcgtc gtcgccgacc ccgccggggt ggcgcagcac
    20881 ggcctcgccc gcctggcggg ccatcgcggc cgccaggccg tcgatctcct cgccgttgac
    20941 ctcgtgggcc agctcccagt cggcgacaca ggagatgttc gagatcgcgt cgccgatgcc
    21001 ggaacggacg taacgggcgg gcgcctcgcg gatcacgtcg aggtcgatga ccacggcgat
    21061 cggggtgggg accccgtagg agccgcgccc gttgtcgttg tccagcgtgg cgaccggcga
    21121 gcacaggccg tcgtgcgaga ggttcgtcgc gacggcgacc atgggcagcc cgacccgcgc
    21181 cgcagcgtac ttcgccacgt cgatgatctt gccgccgccg aggccgacga cggcgtcgta
    21241 ccggttgccc ttgatgccgt cggcgagctt caccgccgag tcgatcgtgc cgtcggacac
    21301 cggataccag tcggcacccg gcaggaccgg ggcgagcctc tccttgaggg cgcgcccgga
    21361 accgtcgctg atcgcgatgg cgagcttgcc cgaggaggag atccgctgat cggccaggag
    21421 acccgccaga tcgtccatgg cgccgcgccg gatgtcgacg acgaccgggg acggaatgag
    21481 ccgggtcagt actggcacgc gatctcccgg cccttcttca ggtcgtcgtg gttgtcgatc
    21541 tcgacccagg tcacggtgcc gatgggggca acgtcgacgg tgaagccgcg gttgacgagc
    21601 tcctggtagc cgtcctcgta gtagaggtcg gggtcgcgct cgaaggtggt cttcagcgcg
    21661 tccgcgagct cctcggcggc gtcggcctcg atgagggtga cgccgatgta ctcgccggtc
    21721 gcggtggccg ggtccatcag cttcgtgatg cgctggacgc ccttgccctc ctccgtgatg
    21781 accttcatct cctcgtcggc gaggaccttc tcggtgtcca gggcgaggat gatcttctgg
    21841 cccttgccgc gggcgtccag gagggtcttc tcgacggaga ccgggtgcac ggtgtcgccg
    21901 ttggcgagga tcacgccgcg cttgatgacg tcacgggcgc accagaggga gtaggcgttg
    21961 ttccactcct cggccttgtc gttgtcgatg agcgtgaggg tgacgccgta ggtcgcttcc
    22021 agctcggcct tgcgggcgta gacggcctcc ttgcggtagc cgacgacgat cgcgacctcg
    22081 gtgagtccga cctccgcgaa gttggcgagc gtgaggtcga ggaccgtctt gtcgccgtcg
    22141 acagggacga gcgccttggg aagcgtgtcc gtgtaggggc gcagacgtcg tcctgcaccg
    22201 gctgccagta cgaggccgat catgcgagtt ctccttcgtc gtgtacggcg ggggccgagg
    22261 aggacaccca gaagcggatg gactccacga gcaccaccag agccacggcg accgcgagcg
    22321 cggtcagggc cgtggtgaaa cctgaggtgt gggtgagtac ggcggcgagg acgaccacca
    22381 gcgcggtccg gccctcgtgt ccaccgatcg tccgcaccag ccactggggc ggcgcgccgg
    22441 tgcccccgcg aatgcggtac accgtgtcgt agtgatggta ggcgacggcc gagaccagcc
    22501 cgaaggccgc cggaacggcg tgcgggacgt cgctgcgggc cgccaccacc aggaccgtga
    22561 cgtactccgc cgcccggaag aacggcggca ccagccagtc gagcgcgccc ttgagcgggc
    22621 gggcgacggc gaggccggag aggaccacgt acaccgctgc ggcggccacg gtcagcgggc
    22681 tgccgtacgg gaggaagagg gcaccgccga tcatgaccag cgtcccgagc agggcgacgg
    22741 ccggggcggt gaaggcgccc cggagtccgg gggcgacggc ggcgacggcc tgcgccaggg
    22801 ggccggagtc ggcgaggtcc gcgagggcct gcgcggcgcg gtcggtgcgg ccggccctgc
    22861 gggtcagcga gcgcagcagg cggcccgccg tggtgtagca ggcggccagg gagcagccga
    22921 cgagcagggc gtagaagacg atgcgcgggg tggtgagcgc ggtgagcacg gcgatcatgg
    22981 cccagcgctc accgatcggc agcacgatca tccggcgcgc ccagaccgtc cagccgacgc
    23041 tgtcgagctt gtcggagagg gcggcggtgg gactggtgtt ggcgaccgcg tcgtggttgg
    23101 cctcgttgaa cgagaagtcc accacgtggc ggcaggcctg gaggaccatc gcgccgagcg
    23161 ccagcaccca gacgtcatca ccgccgcgga cggcgccgat ggcgagcccg gcgtagtacg
    23221 cgtactcctt ggcccggtcg aaggtggcgt ccagccaggc gcccatcgtg gagtactgca
    23281 acgagtagcg ggccagctgc ccgtcggtgc agtccagcac gaaggagacc aggagcagga
    23341 tcccggcggc gacgtagccg ccccgggtgc cggtggccgc gctgccggcc gcgatgagcg
    23401 cggtgatcag cgaggcggtg gtgacctggt tcggggtgag gttgcggcgg gcgcaccaac
    23461 gggcgatgta gcgggagtag gggctgatgc agtacgtggt gaagaacccg tcgtgggcct
    23521 tcaccgcgtt gcgcagccgt accgcctcgt cgtcgaccga ggcgaggccc gcctcggcgg
    23581 cggcctgctg ctccgggtcc gtggggacgg ccgcgacgag cgagccgagg gcggggcgct
    23641 gtacggcggt gccctcggcc tccagcgcga cggcgatccg gccggggacg gtgcggtcct
    23701 cgggcgcggg gtcggcgtcc ggctcgacga ccggggcgcc cgcgccgacc gcggcggcgg
    23761 tgcggtgcag ggcccgcagc agggcgccgc gcgcctcggg ctgggcggtg agcgcgcccg
    23821 ggacggtggc ggcggggaag cgcgggtcgg tcagcccgag ccgcagcgcg tggacgtggc
    23881 ccacgaaacg cgggtcgacg agggcgaccc ggcggcccgc cggaacggcg gcgaggagcg
    23941 ttgcggcgtc accggcgtcg gcggcggtct gcacgtcgaa gcccagggac cgcaggtcgt
    24001 ccgcgagcga cgacccgggt accggcgtac cggtgaggat ggcggtcgac agacgaactc
    24061 actccttggc actgacgtgg acggcacgcg gcggcacggc cacggggcgg gccggcggcg
    24121 tgtcggctga ggctatcgga tgaacggaag gccgaattca ccgcccgttt gtgcgctgta
    24181 cgggtggacc tgcaagcccg ggcggcgttg gcgatcatca tcatcgatcg ggggcccggc
    24241 ccacaaaccg ctgtccggcg ccggaggacg ggccagggcc tgtcgtcgga tcgggccggg
    24301 cacgcgggcc cggcatgatc cgaacgacag gcccttaggc tgacgggcat gacatggctg
    24361 atcacaggcg gggcgggata catcggggca catgtggcgc gggccatggt ggccgcgggc
    24421 gagcgggtcg tggtgctcga cgaccgctcc agcggcatcg tggaacggct gccggacgcg
    24481 gtcacgctgg tggagggttc ggcctccgac cgggccctgc tggaccgggt gctggccgac
    24541 cacgcggtga gcggcgtggt gcatctcgcg gcgaagaagc aggtcggcga gtccgtggag
    24601 aagccgctgc tgtactaccg ggagaacgtg gccgggctgg ccgtcctgct ggaggccgtg
    24661 gtcgcggcgg gggtgtcgcg cttcctcttc tcgtcgtcgg cggccgtcta cggcgtaccg
    24721 gacgtggacc tcatcacgga ggagacgccc tgcctcccga tcaacccgta cggcgagacc
    24781 aagctcaccg gggagtggct ggtgcgggcg gcggggaagg cccacgggat ctcgaccgcc
    24841 tgtctgcggt acttcaacgt ggcgggcgcc gccgcacccg agctcgcgga caccggggtc
    24901 ttcaacatcg tgccgatgat gttcgagcgg ctgacgcgtg gcgaggcccc gcggatcttc
    24961 ggcgacgact acccgacgcc ggacggcacc tgcatccgcg actacatcca tgtcgccgac
    25021 ctggcggagg cgcatctcgc cgtcgcgcgg cggctggacg gagcgggcgc cggcgatctg
    25081 acgctgaacg tcggccgggg cgagggggtc tcggtgcggg agctggccga ggtgatcggc
    25141 aaggtgacgg gccgcagccc ggagccggtg gtcgaggcgc ggcgggccgg tgacgcgccg
    25201 aaggcggtgg cgtcggccgc gcggatcacc gaggagctgg gctggacggc acggcggggt
    25261 gtgcgcgaga tggtggagtc ggcctgggag ggctggtgcc tgcgccaccc cgaggcctgc
    25321 gcgcaggggc gcggctgacc gcttccgcga ggcgggacat caatcgtgtc aacgctctga
    25381 cctgcggaac gtttccgcag gtcagagcac atgacaacgg tgttcagtcc cgtgttgccc
    25441 gatacccccc acccgtagtt cactgggcct ggacggggtg gttgcgcccc ggcacgtcct
    25501 acggacctgg aggcgtttcg catgggggct ggccacgatc acgggcatac gcacggcggg
    25561 ccgccgccga cgggcacggc ggccgccgcg taccggggca ggctccgggt ggccctggcg
    25621 atcacgctga gcgtgatggt catggagatc gtcggcgggg tgctctccga ctcgctggcc
    25681 ctgatcgcgg acgccgccca catggccacc gacgctctgg gcctcgggat ggcgctgctc
    25741 gccatccact tcgccaaccg tccggccgga ccgaaccgca ccttcggttt cgcccgcgcg
    25801 gagatcctgg cggcgctcgc gaactgtgtg ctgctgctgg gggtcggcgg ctttctggtc
    25861 ttcgaggcgg tcgagcggtt catcaccccg gccgagacga agggcggcct ggcgatcgcg
    25921 ttcgccgccg tcggtctggt ggccaacgtc gtctccctct cgctgctgat gcgcgggcag
    25981 caggagagcc tgaatgtgcg gggcgcctat ctggaggtgc tggccgacac cctgggctcg
    26041 ctcgccgtga tcgtctcggc cggcgtcatc atggcgaccg gctggcagcc cgccgacccg
    26101 atcgcctccc tggtgatcgg cctgatgatc gtcccccgga ccgtgaagct gctgcgcgag
    26161 accctgaacg tgctcctgga ggcggcgccc aagggtgtgg acatggcgga ggtacgggcc
    26221 cacatcacgg agctgcccgg ggtcctggac gtccacgatc tgcacgcctg gacgatcacc
    26281 tcgggcatgc cggtgctctc cgcccacgtg gtggtacgcc aggaggtgct cgactcgaca
    26341 ggacacgaga aggtgctgca cgagctgcag ggctgcctcg gcgaccactt cgacgtggag
    26401 cactgcacct tccagctgga gccgagcggt cacgcggcgc acgagccgcg gctctgccac
    26461 tgaggccgcc gggtgcgggc cgaggcagtg ctagtctcgt ttcgctgaga cgttcgagtc
    26521 tcgcggtgga gcggagcccg gtgacaccgg gaccttacga aaggagctga ggttga
//
