LOCUS       NZ_MUXL01000001        20891 bp    DNA     linear   CON 09-SEP-2024
DEFINITION  Bacillus spizizenii strain AS2 scaffold_1, whole genome shotgun
            sequence.
ACCESSION   NZ_MUXL01000001
VERSION     NZ_MUXL01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus spizizenii
  ORGANISM  Bacillus spizizenii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 1554061)
  AUTHORS   Al-Bahry,S.N., Al-Wahaibi,Y.M., Al-Sayegh,A., Elshafie,A.,
            Al-Bemani,A.S. and Joshi,S.J.
  TITLE     Whole Genome Sequence of Heavy-oil Degrading and Biosurfactant
            Producing Bacillus subtilis AS2
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1554061)
  AUTHORS   Al-Bahry,S.N., Al-Wahaibi,Y.M., Al-Sayegh,A., Elshafie,A.,
            Al-Bemani,A.S. and Joshi,S.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-FEB-2017) Biology, Sultan Qaboos University, Al-Khod,
            Muscat 123, Oman
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_002155045.1
            Current Name                      :: Bacillus intestinalis
            Previous Name                     :: Bacillus subtilis
            Date Updated                      :: 2018-08-15
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_002027305.1
            A1 Name                           :: Bacillus intestinalis
            A1 ANI                            :: 99.23349%
            A1 Query Coverage                 :: 95.49%
            A1 Subject Coverage               :: 95.35%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_000332645.1
            A2 Name                           :: Bacillus subtilis
            A2 ANI                            :: 94.5332%
            A2 Query Coverage                 :: 92.3%
            A2 Subject Coverage               :: 85.9%
            ##Taxonomic-Update-Statistics-END##
            ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 2.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002155045.1-RS_2024_09_09
            Annotation Date                   :: 09/09/2024 01:52:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,198
            CDSs (total)                      :: 4,090
            Genes (coding)                    :: 3,976
            CDSs (with protein)               :: 3,976
            Genes (RNA)                       :: 108
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 4, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 73 of 114
            Pseudo Genes (incomplete)         :: 53 of 114
            Pseudo Genes (internal stop)      :: 12 of 114
            Pseudo Genes (multiple problems)  :: 21 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:09:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 428331
            Orig. end                         :: 449222
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MUXL01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20891
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10891](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10891
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            519..725
                     /gene="spoIIIAC"
                     /locus_tag="B0W20_RS02325"
                     /old_locus_tag="B0W20_02310"
     CDS             519..725
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390321.1"
                     /locus_tag="B0W20_RS02325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02310"
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_003153142.1"
                     /transl_table=11
                     /translation="MGVDVNVIFQIAGVGIVVAFLHTILDQMGKKEYAQWVTLLGFIYI
                     LFMVATIVDDLFKKIKAVFLFQG"
     gene            732..1133
                     /gene="spoIIIAD"
                     /locus_tag="B0W20_RS02330"
                     /old_locus_tag="B0W20_02315"
     CDS             732..1133
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390320.1"
                     /locus_tag="B0W20_RS02330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02315"
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_003230228.1"
                     /transl_table=11
                     /translation="MQIDIVQIVGLGLIATFLSLIVKEQKPTFAFLIVVFAGCAIFLYL
                     VDQIYDIIRMIEKIAINANVNMVYVETILKIIGIAYIAEFGAQLTKDAGQGAIASKIEL
                     AGKILILVMAVPILTVIIETILGLIPSMS"
     gene            1152..2351
                     /gene="spoIIIAE"
                     /locus_tag="B0W20_RS02335"
                     /old_locus_tag="B0W20_02320"
     CDS             1152..2351
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390319.2"
                     /locus_tag="B0W20_RS02335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02320"
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_014114372.1"
                     /transl_table=11
                     /translation="MKRFQWALLLAVLIIAGRADIVQAAGDAEQTEDHAETAEQLAERT
                     AASLETDKISEFWNDIMTEYGGLLPESQKGSIIEFINGDKSFSPQEWLKALFSYLFHEV
                     LANGKLLGTLILLTIFCVILQLLQNAFQQSTVSKVAYSIVYMVLIILALNSFHVAINYA
                     TEAIQTMTSFILALIPLLLALLASSGGAVSAAFFHPVILFLMNTSGLLIQNIVMPLIFL
                     SAILSIVSTMTEQYKVTQLANLLRNIAIGALAVFLTIFLGVISVQGASAAVTDGITLRT
                     AKFITGNFIPVLGRMFTDATDTVISASLLLKNTVGILGVAILICIAAFPAIKVLSLAFI
                     YKLAAAILQPLGGGPVITCLDVISKSVIYIFAALAIVSLMFFLSLTVIITAGNLTMMMK
                     "
     gene            2365..2985
                     /gene="spoIIIAF"
                     /locus_tag="B0W20_RS02340"
                     /old_locus_tag="B0W20_02325"
     CDS             2365..2985
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390318.1"
                     /locus_tag="B0W20_RS02340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02325"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_061186888.1"
                     /transl_table=11
                     /translation="MSFLTEWLTTIVLFILFAIVIDMLLPSSSMQKYAKMVVSLLLIVV
                     MLTPIFKLFNTDPAVIFEYLTKNGQSESADIKNQINSKKIEIQASQRAYILEEMAVQLK
                     KKAEERFSHDEYKVGNIKLTAGEKVDSEEDIQTISVYMAPSSEKTVQTVAPVHIDTDHA
                     YVTKEAAEQKEAKQIQSQLADIWEIGSEKITVHMEGGESVGNE"
     gene            2978..3667
                     /gene="spoIIIAG"
                     /locus_tag="B0W20_RS02345"
                     /old_locus_tag="B0W20_02330"
     CDS             2978..3667
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390317.2"
                     /locus_tag="B0W20_RS02345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02330"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_087986889.1"
                     /transl_table=11
                     /translation="MNKNGLWNVLKKQFLPGQTKDGEKPKLTKYHYFLFVFVLGVSFML
                     VSQLFSSPEKTENAKTITPVSSQDTKVSKEKTAEVFKASKPDEPKDSIDDYEKEYENQL
                     KEILETIIGVDDVSVVVNVDATSLKVYEKNKSNKNTTTEETDKEGGTRSVTDQTSEEEI
                     VMIKNGDKETPVVVQTKKPDIRGVLVVAQGVDNVQIKQTIIEAVTRVLDVPSHRVAVAP
                     KKIKEDS"
     gene            3668..4324
                     /gene="spoIIIAH"
                     /locus_tag="B0W20_RS02350"
                     /old_locus_tag="B0W20_02335"
     CDS             3668..4324
                     /codon_start=1
                     /gene="spoIIIAH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390316.2"
                     /locus_tag="B0W20_RS02350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02335"
                     /product="stage III sporulation ratchet engulfment protein
                     SpoIIIAH"
                     /protein_id="WP_014114369.1"
                     /transl_table=11
                     /translation="MLKKQTVWLLTMLSLVVVLSVYYIMSPESKNAVQMQSEKSASDSG
                     EVATEKAPPKQDTKEKNGTETETEKEDGTKGTKDSSADKETSAEASEKGTVVTETADDD
                     LFTTYRLDLEDARSKEREELNAIVSSDDATAKEKSEAYDKMTALSEVEGTEKQLETLIK
                     TQGYEDALVNAEGDKINITVKSDKHSKSKATAIIDLVAKEIKTMKDVAVTFEPSK"
     misc_feature    complement(3672..3681)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            4481..4963
                     /gene="accB"
                     /locus_tag="B0W20_RS02355"
                     /old_locus_tag="B0W20_02340"
     CDS             4481..4963
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390315.1"
                     /locus_tag="B0W20_RS02355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02340"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_014114368.1"
                     /transl_table=11
                     /translation="MLNIKEIHELIKAIDESTIDEFVYENEGVSLKLKKHEAGTVQVMQ
                     QAPAAPVQAQAPQAVQPQAQQAAPAPAQEETKQDENLHKITSPMVGTFYASSSPEAGPY
                     VTAGSKVNENTVVCIVEAMKLFNEIEAEVKGEIVEVLVENGQLVEYGQPLFLVKAE"
     gene            4975..6327
                     /gene="accC"
                     /locus_tag="B0W20_RS02360"
                     /old_locus_tag="B0W20_02345"
     CDS             4975..6327
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390314.2"
                     /locus_tag="B0W20_RS02360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02345"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_014114367.1"
                     /sec_met_domain="RimK (E-value: 4.2e-07, bitscore: 26.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.4e-08, bitscore:
                     31.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.7e-10,
                     bitscore: 36.6, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.2e-06, bitscore:
                     24.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKLLIANRGEIAVRIIRACKELGIETVAVYSEADKDALHVQMA
                     DEAFCIGPKASKDSYLNVTNIVSVAKLTGTDAIHPGYGFLAENADFAELCEEVNVTFVG
                     PSADAISKMGTKDVARETMKQAGVPIVPGSQGIIENVEEAVSLANEIGYPVIIKATAGG
                     GGKGIRVARTEEELINGIKITQQEAATAFGNPGVYIEKYIEDFRHVEIQVLADNYGNTI
                     HLGERDCSIQRRLQKLLEESPSPALDSEIREQMGDAAVKAAKAVGYTGAGTVEFIYDYN
                     EQRYYFMEMNTRIQVEHPVTEMVTGTDLIKEQIKVASGMELSLKQEDVEFEGWAIECRI
                     NAENPSKNFMPSPGEIKMYLPPGGLGVRIDSAAYPGYSIPPYYDSMIAKVITYGKTRDE
                     AIARMKRALSEFVIEGIETTIPFHLKLLEHETFVGGEFNTKFLETYDVMGS"
     gene            6348..6755
                     /gene="yqhY"
                     /locus_tag="B0W20_RS02365"
                     /old_locus_tag="B0W20_02350"
     CDS             6348..6755
                     /codon_start=1
                     /gene="yqhY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390313.2"
                     /locus_tag="B0W20_RS02365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02350"
                     /product="fatty acid biosynthesis protein YqhY"
                     /protein_id="WP_003236896.1"
                     /transl_table=11
                     /translation="MKDNSLLKMDQEDTHLGKVEIAPEVIEVIAGIAASEVDGVAEMRG
                     NFATGVVERFGKVNHGKGVKVDLADDGITIDVYCVVTFGVSIPKVAASVQENIRQTLLN
                     MTSLSINEINIHIVGIQFDTKAQEVQIDEEM"
     misc_feature    complement(6775..6789)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 20.5"
                     /tool="antismash"
     misc_feature    complement(6918..6933)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.84"
                     /tool="antismash"
     gene            7020..7415
                     /gene="nusB"
                     /locus_tag="B0W20_RS02370"
                     /old_locus_tag="B0W20_02355"
     CDS             7020..7415
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390312.2"
                     /locus_tag="B0W20_RS02370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02355"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_014114366.1"
                     /transl_table=11
                     /translation="MKRRTAREKALQALFQIDVSDIAVNEAIEHALDEEKTDPFFEQLV
                     HGVLEHQVQLDEMISKHLVNWKLDRIANVDRAILRLAAYEMAYAEDIPVNVSMNEAIEL
                     AKRFGDDKATKFVNGVLSNIKSDIDQS"
     gene            7427..8278
                     /gene="folD"
                     /locus_tag="B0W20_RS02375"
                     /old_locus_tag="B0W20_02360"
     CDS             7427..8278
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390311.1"
                     /locus_tag="B0W20_RS02375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02360"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_014114365.1"
                     /transl_table=11
                     /translation="MTATIIDGKETAREKREQLAKEVEELKKQGVTPGLAVILIGDDPA
                     SHSYVRGKKKAAETMGMNFKLDQFDSSLTEAELLSIIDQYNQDPEFHGILVQLPLPDHI
                     SEKAVIERISPDKDVDGFHPLNVGKMLLGEDTFLPCTPHGIVELLKKTNIDLSGKEVVV
                     VGRSNIVGKPVGQLLLNENATVTYCHSRTENMTEHTKKADILVVAVGRANFISADQIKE
                     GAVVIDVGVNRLESGKLCGDVEFEGAKEKASFITPVPGGVGPMTITMLAHNTVKSAKRT
                     LS"
     gene            8414..9760
                     /gene="xseA"
                     /locus_tag="B0W20_RS02380"
                     /old_locus_tag="B0W20_02365"
     CDS             8414..9760
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390310.2"
                     /locus_tag="B0W20_RS02380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02365"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_014114364.1"
                     /transl_table=11
                     /translation="MGETAFVTVSALTKYIKRKFDVDPHLENIWIKGELSNVKIHTRGH
                     IYFTLKDENARMQSVMFARQSERLPFKPENGMKVLVRGGISVYEPSGNYQLYAKEMQPD
                     GVGALYLAYEELKKKLAGEGLFDDRYKKQIPAFPATIGVVTSPTGAAVRDVITTLKRRY
                     PLVKVLVLPALVQGENASRSIVSRIEEANEKEMCDVLIVGRGGGSIEELWAFNEEIVAR
                     AIFASNIPIISAVGHETDFTISDFVADIRAATPTGAAEIAVPHTTDLIERTKTAEVRMT
                     RAMQQHLGQKKERIQTLQSSYAFRFPKRLYAQKEQQFDLAYQQFQAQLTALLDRKNRQL
                     ERETYRLEALHPHEQLKQARTRYEEQTNQLRKNMNIQMKQLHSQFQTVLGKLNALSPLQ
                     VMERGYSLAYKEDELIKSVNQIEEKDQLEVKLKDGVLTCEVLEKRGEEK"
     gene            9757..10011
                     /locus_tag="B0W20_RS02385"
                     /old_locus_tag="B0W20_02370"
     CDS             9757..10011
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390309.2"
                     /locus_tag="B0W20_RS02385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02370"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_003226409.1"
                     /transl_table=11
                     /translation="MTDVKKNENMTFEEAMKGLESIVSKLEEGDVPLEQAINYFQEGMA
                     LSKMCHEKLQKVEKQMDFILKEDGELAPFSVQEEDEGDK"
     gene            10001..10891
                     /locus_tag="B0W20_RS02390"
                     /old_locus_tag="B0W20_02375"
     CDS             10001..10891
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390308.2"
                     /locus_tag="B0W20_RS02390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02375"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_087986890.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.4e-63, bitscore:
                     210.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNKLTSFLAERKKTIENQLSVYTEKLDMPDSLKKSMLYSLEAGG
                     KRLRPLIVLAVLNAYGKSEKDGIPVGCAVEMIHTYSLIHDDLPCMDDDDLRRGKPTNHK
                     VFGEATAVLAGDGLLTESFKLITSHVSDEVSAEKRLRLVNELISAAGTEGMVGGQVADM
                     EAENRQVTLEELESIHERKTAKLLGFSVIAGAILADAPEEDIETLRTFSSHIGIGFQIR
                     DDILDLEGSEEKIGKRVGSDTTNEKSTYPSLLSLEGAKHKLDVHIKEAKRLIGGLSLQK
                     DLLYELCDLIAARDH"
     gene            11072..12973
                     /gene="dxs"
                     /locus_tag="B0W20_RS02395"
                     /old_locus_tag="B0W20_02380"
     CDS             11072..12973
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390307.1"
                     /locus_tag="B0W20_RS02395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02380"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_061186892.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 5.1e-117,
                     bitscore: 386.5, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLSIQDPSFLKNMSIDELEKLSDEIRQFLITTLSASGGHIGPN
                     LGVVELTVALHKEFNSPKDKFLWDVGHQSYVHKLLTGRGKEFATLRQYKGLCGFPKRSE
                     SEHDVWETGHSSTSLSGAMGMAAARDIKGTDEFIIPIIGDGALTGGMALEALNHIGDEK
                     KDMIVILNDNEMSIAPNVGAIHSMLGRLRTAGKYQWVKDELEYLFKKIPAVGGKLAATA
                     ERIKDSLKYMLVSGMFFEELGFTYLGPVDGHSYHELIENLQYAKKTKGPVLLHVITKKG
                     KGYKPAETDTIGTWHGTGPYKINTGDFVKPKAAAPSWSGLVSGTVQRMAREDGRIVAIT
                     PAMPVGSKLEGFAKEFPDRMFDVGIAEQHAATMAAAMAMQGMKPFLAIYSTFLQRAYDQ
                     VVHDICRQNANVFIGIDRAGLVGADGETHQGVFDIAFMRHIPNIVLMMPKDENEGQHMV
                     HTALSYDEGPIAMRFPRGNGLGVKMDEQLKTIPIGTWEVLRPGNDAVILTFGTTIEMAL
                     EAAEELQKEGLSVRVVNARFIKPIDEKMMKSILKEGLPILTIEEAVLEGGFGSSILEFA
                     HDQGEYHTPIDRMGIPDRFIEHGSVTALLEEIGLTKQQVANRIRLLMPPKTHKGIGS"
     gene            12970..13815
                     /locus_tag="B0W20_RS02400"
                     /old_locus_tag="B0W20_02385"
     CDS             12970..13815
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390306.2"
                     /locus_tag="B0W20_RS02400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02385"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_087986891.1"
                     /transl_table=11
                     /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVNDKIMIDIGSSTGGFTDCALQNG
                     AKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRL
                     ILPVLKTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHVDVLKRMNSFSADEGYI
                     CKGLSFSPITGGDGNIEFLLHLHWPGEGQEGQELPEEEIIRVVEEAHKTLKEKKADVPE
                     "
     gene            13912..14361
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /locus_tag="B0W20_RS02405"
                     /old_locus_tag="B0W20_02390"
     CDS             13912..14361
                     /codon_start=1
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390305.1"
                     /locus_tag="B0W20_RS02405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02390"
                     /product="arginine repressor ArgR"
                     /protein_id="WP_014114358.1"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLDWDEIMGTICGDDTILIICRTPEDTDGVKNRLLELL"
     gene            14397..16127
                     /gene="recN"
                     /locus_tag="B0W20_RS02410"
                     /old_locus_tag="B0W20_02395"
     CDS             14397..16127
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390304.2"
                     /locus_tag="B0W20_RS02410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02395"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_087986892.1"
                     /transl_table=11
                     /translation="MLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRYGETKAELEGLFLLESGHPVFDVCTEQGIDVSDEMIVMRRDISSSGKS
                     VCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALQAYQ
                     EEYHRYMKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERQQISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKLSESVSNSYYLLEDA
                     TFQMRNMLDELEYDPERLNYIETRLNEIKQLKRKYGATVEEILEYASKIEEEIDQIENR
                     DSHLQSVKKELDSVGKDVAVEAANVSQIRKAWAKKLADEIHRELKSLYMEKSTFDTEFK
                     IRTASRNEEAPIVNGQPVQLTDQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAI
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTH
                     LYIAKELKDGRTTTRVKPLSKQEKVVEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG
                     "
     misc_feature    complement(16158..16173)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.53"
                     /tool="antismash"
     gene            16301..17581
                     /gene="spoIVB"
                     /locus_tag="B0W20_RS02415"
                     /old_locus_tag="B0W20_02400"
     CDS             16301..17581
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390303.2"
                     /locus_tag="B0W20_RS02415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02400"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_014114356.1"
                     /transl_table=11
                     /translation="MPDNIRKAVGLILLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQA
                     IETGLSVNAHAQESSEAFTVKKDPHEIKVTGKKSGESELVYDLAGFPIKKTKVQVLPDL
                     KVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIEAGDIIIEMNGQKIEKMN
                     DVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEAEGKYRIGLYIRDSAAGIGTMT
                     FYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLARFSSER
                     KTIGDINRNSPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDDKVEKFD
                     IEIVSTTPQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVND
                     PTSGYGVHIEWMLSEAGIDIYEKEKAS"
     misc_feature    complement(17583..17599)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.05"
                     /tool="antismash"
     gene            17858..18661
                     /gene="spo0A"
                     /locus_tag="B0W20_RS02425"
                     /old_locus_tag="B0W20_02410"
     CDS             17858..18661
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /GO_process="GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390302.1"
                     /locus_tag="B0W20_RS02425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02410"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_003226427.1"
                     /transl_table=11
                     /translation="MEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLF
                     KEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHE
                     IGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEV
                     AWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS"
     gene            18808..18987
                     /locus_tag="B0W20_RS02430"
                     /old_locus_tag="B0W20_02415"
     CDS             18808..18987
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003236884.1"
                     /locus_tag="B0W20_RS02430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02415"
                     /product="hypothetical protein"
                     /protein_id="WP_087986893.1"
                     /transl_table=11
                     /translation="MFEKYGLLMALFILALCVNSNIMTESHILSTLIDFISFAVMVSCV
                     FAAWIIKNKQSGSN"
     gene            complement(19204..20322)
                     /locus_tag="B0W20_RS02435"
                     /old_locus_tag="B0W20_02420"
     CDS             complement(19204..20322)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390301.1"
                     /locus_tag="B0W20_RS02435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B0W20_02420"
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="WP_072566533.1"
                     /transl_table=11
                     /translation="MNPKYKPLFEPFTFKSGVTIDNRITVAPMTHYASNEDGTISEAEL
                     DYIIPRSKEMGMVITACANVTPDGKAFPGQPAIHDDSNIPGLKKLAQAIQAQGAKAVVQ
                     IHHGGIECPSELVPQQEVVAPSDVFDDGKQIARALTDEEVENIVKAFGEATRRAIEAGF
                     DGVEIHGANGYLIQQFYSPKTNQRTDRWGGSDEKRLAFPLAIVDEVKKAAAEHAKGAFL
                     VGYRLSPEEPETPGLTMTETFTLVDALGDKELDYLHISLMDVNSKARRGADPTRTRMDL
                     LNERVGNKVPLIAVGSIHSADDALAVIENGIPLVALGREILVDPDWTVKVKEGREKQIE
                     TVIKGTDKEKYHLPEPLWQAIVNTPGWVPYKD"
     gene            complement(20395..20515)
                     /locus_tag="B0W20_RS21420"
                     /pseudo=""
     CDS             complement(20395..20515)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003236876.1"
                     /locus_tag="B0W20_RS21420"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLLAAACHQLHHRPPNQRRLQSPRKRAQKTSLCFQDIQPV"
ORIGIN
        1 tgtattcatt gtggtggcga caacatggac aggttttgag atggcgaaga tttatacaga
       61 acggccgcgg caaatccgcc agctgcgtgc ggcgctccaa tccctcgagg ctgaaatcat
      121 gtacggccat acaccgcttc atattgcttc acagcagatt gccaagcagc tggcacagcc
      181 tgtttcagct ctttttatca cgttcagtga tcagctggac aaaggaagtg attctgcgaa
      241 aatggcgtgg gagcaaagct taaagaaggt gtgggacacc atgtctttga aaaaaagcga
      301 atatgaagtg ctgaagcaat ttggtgagac gctcgggatt catgatcgaa tctcgcagca
      361 aaagcacatc aagctggcgc tgacacattt ggaagcctcg gaagcggatg ctgagcaggc
      421 acaagcgaaa aatgaaaaaa tgataaaaag tttgggcttt ttagcgggct tgttactcat
      481 tcttctattg atgtaaacgt gaggggagca aaaataaaat gggagtagac gtgaatgtca
      541 tatttcaaat cgccggagtg ggaatcgtgg ttgcattttt acacacgatt ttggatcaga
      601 tgggcaaaaa agaatacgcc cagtgggtga cgctgttagg ttttatctat attttattta
      661 tggtcgcaac gattgtagat gaccttttta aaaagataaa agctgtgttt ttattccaag
      721 gatagggggg cttgcagatt gacattgttc aaattgtagg tttagggctg atcgccacct
      781 tcctttcttt gattgtaaaa gaacaaaagc cgacttttgc gtttttaatc gtcgtgtttg
      841 ccggatgtgc catttttctt tatttggtag accaaatcta cgatattatt cgaatgatag
      901 agaaaatcgc gattaatgca aacgtcaaca tggtctatgt tgaaaccatt ttaaagatta
      961 tcggaattgc ctatattgct gaattcgggg cgcagctcac aaaagatgcc ggacaagggg
     1021 ccatcgcctc gaaaatagaa ttggcgggga aaattttaat tctcgttatg gctgtgccta
     1081 ttttaaccgt cattatcgaa acgattctcg gacttatacc ttctatgtca taaccgaaag
     1141 gaggcggtag attgaagcgt tttcaatggg ctttgcttct ggccgtgctg atcatagcag
     1201 gccgtgcaga cattgtacaa gcagccggtg acgccgaaca aacggaagac catgctgaaa
     1261 cggctgagca attagcggaa aggacagcgg cctcgcttga aacagacaag attagtgaat
     1321 tttggaatga cattatgaca gagtacggtg gactgctgcc ggaaagtcaa aaaggcagca
     1381 taattgagtt tatcaatggc gataaatcat tttcaccgca agaatggctg aaagctctct
     1441 tttcttattt gtttcatgaa gtgcttgcca acggaaagct gttgggcaca ttgattttgc
     1501 tcacgatatt ttgcgttatc ctgcagcttc tgcaaaatgc atttcaacaa agcaccgtca
     1561 gtaaggtcgc ttactcaatt gtgtacatgg tgctgattat ccttgcgcta aacagttttc
     1621 atgtggcaat caattatgcg acagaggcca ttcagacgat gaccagcttt atcctggcgc
     1681 tcattccgct cctcttagcg cttttggctt cctcaggcgg agctgtatct gcagccttct
     1741 ttcatcctgt tatcctcttt ctgatgaaca cgagcggtct tttgattcag aatattgtca
     1801 tgccgctcat tttcttatca gcgattctga gcattgtcag cacaatgacc gaacaatata
     1861 aagtaacgca gctggccaac ctgcttagaa atatcgccat cggggcgctc gccgtctttc
     1921 tcaccatctt tctcggtgtc atctctgttc agggagcctc ggctgcagtg acagacggca
     1981 ttacgctcag gacggctaaa tttataaccg gaaactttat tcctgtgctt ggccgaatgt
     2041 ttacagacgc gacagataca gtgatcagcg cttccttact gctgaaaaat acagtaggga
     2101 ttctcggagt cgctattttg atctgtattg cggcttttcc ggcaatcaaa gtgctttccc
     2161 tcgcttttat ttataagctg gcagccgcga ttcttcagcc gcttggaggc gggcccgtca
     2221 taacctgcct cgacgtcatc agcaaaagcg tcatttatat ttttgcagct ctcgccattg
     2281 tgtctctcat gtttttttta agccttaccg tcataatcac agccggaaac ctcacgatga
     2341 tgatgaaata aaggaggctg gcggatgagt tttttaactg aatggcttac caccatcgtg
     2401 ttgtttatcc tatttgcaat tgtgattgat atgctgctgc caagctctag catgcaaaag
     2461 tacgcaaaaa tggtagtcag cctgctctta attgtcgtca tgctcacgcc gatttttaag
     2521 cttttcaaca cagaccctgc agtcatcttt gaatatctta caaaaaacgg gcagtcagag
     2581 tctgccgaca taaaaaatca aatcaattca aaaaaaatag aaatacaagc ttcccagcgt
     2641 gcatatattt tagaagaaat ggctgtccaa ctaaaaaaga aagcggagga gagattcagt
     2701 catgatgaat acaaagtagg caacatcaaa ctcacggcag gagaaaaggt agattcagaa
     2761 gaggatattc aaacaatcag cgtgtatatg gccccgtctt ctgaaaaaac ggtccaaacg
     2821 gtcgcgccgg tccacattga tacagatcat gcatacgtaa cgaaagaagc agccgaacaa
     2881 aaagaagcca aacagatcca gtcacagctc gcggacattt gggaaatcgg aagtgagaaa
     2941 attacggttc atatggaagg cggggagagt gtcggcaatg aataaaaacg gattatggaa
     3001 tgtattgaaa aagcagtttc ttccggggca aacgaaggac ggtgaaaaac cgaagctgac
     3061 caaatatcat tactttctgt tcgtttttgt tctcggagtt tcctttatgc ttgtcagcca
     3121 gctgttttct tcacctgaga aaacagaaaa cgccaaaacg ataacgccag tatcatcaca
     3181 agataccaaa gtcagcaaag agaaaacagc cgaagtgttt aaagcctcaa aacctgatga
     3241 acctaaggac tcgatcgatg attatgaaaa agaatacgaa aatcagctga aagaaattct
     3301 tgaaacgatc ataggtgtgg acgatgtctc tgtagtcgtg aatgttgatg caacgtcgct
     3361 gaaagtatac gaaaaaaaca aatcaaacaa aaatacaacc actgaagaaa cagacaaaga
     3421 aggcggaaca agaagcgtta cagaccagac atcagaagaa gaaatcgtca tgatcaaaaa
     3481 cggcgataag gaaacaccag tcgtcgtcca aacgaaaaag cctgatatac gcggtgtact
     3541 cgttgttgct caaggagtgg acaacgttca aataaaacaa accattattg aagcggtgac
     3601 acgggtcctg gatgttccaa gccaccgggt tgcggttgcc cctaaaaaaa taaaggagga
     3661 ttcataaatg ctcaaaaaac aaaccgtttg gctattaaca atgctcagtc ttgtcgtggt
     3721 gttaagcgtc tactatatca tgtcgccgga aagcaaaaat gccgtgcaaa tgcaaagtga
     3781 aaaaagcgcg tctgacagtg gagaggtcgc aactgaaaaa gctcctccca agcaagacac
     3841 aaaggaaaaa aacggtacag aaactgaaac agaaaaagag gatggaacaa agggcacaaa
     3901 agattcatca gcagacaagg agacatccgc tgaagctagt gaaaaaggaa ctgttgtaac
     3961 agaaacagcc gatgatgatc tgttcacgac gtaccgtctt gatttagaag atgccagaag
     4021 caaagaaaga gaagaactga atgccattgt gtcaagcgat gatgcaacag caaaggaaaa
     4081 gagcgaagca tatgataaaa tgacggctct cagtgaagtg gaaggaacag aaaaacagct
     4141 ggaaacgctt attaaaacac aaggctacga agacgcgctc gtcaatgctg aaggagataa
     4201 aatcaacatt acagtcaaat cagacaaaca ctccaaatcg aaggcgacag ccattataga
     4261 ccttgtggca aaagaaatca aaacaatgaa agacgtcgct gtcacatttg aaccatccaa
     4321 gtaaaaaaga ggaaaaacac gcccgcttaa acagcgggct ttttggcgtg ccaatcatat
     4381 tagagttgaa ttcaaaagtc cgctcctgta agatgaacat agtatgtact tttagtagta
     4441 acctataaaa aagaaatttc atacatagga gtgcgattga atgttaaata ttaaagaaat
     4501 ccacgagctg attaaagcaa ttgacgagtc tacaattgac gaattcgtat atgaaaatga
     4561 aggtgtatcc ttaaaactga aaaaacatga agcaggcact gttcaagtca tgcagcaggc
     4621 gccggcagca cctgtacagg cacaggctcc gcaggcagtt cagccgcaag cgcagcaagc
     4681 agcgccagca cctgcccaag aagaaactaa gcaagatgag aatctgcata aaatcacttc
     4741 accaatggta ggaacatttt atgcatcttc atctccggaa gctggcccgt atgtaacggc
     4801 tggttcaaaa gtaaatgaaa acacagttgt ctgcattgta gaagcgatga agcttttcaa
     4861 cgaaatcgaa gcggaagtaa aaggcgaaat cgttgaagta ttagtagaaa acggccagct
     4921 ggtcgaatac ggacaacctc tatttcttgt aaaagcagag taaggagact taacatgatt
     4981 aaaaagctat tgatcgccaa ccgaggagaa attgctgtca gaatcatcag agcctgcaaa
     5041 gagctcggaa ttgagactgt cgctgtttat tcagaagctg ataaagatgc ccttcatgtt
     5101 caaatggccg atgaagcttt ttgtatcgga ccgaaagcat caaaagacag ctatttaaac
     5161 gttacaaata ttgtgagtgt tgcgaagctg acaggcacgg atgctattca cccgggatat
     5221 gggtttttag ctgaaaatgc tgatttcgcg gaattatgtg aagaagttaa cgtcacattt
     5281 gtcggcccga gcgctgacgc catttcaaaa atgggaacaa aagacgttgc gcgggaaacg
     5341 atgaaacagg ccggcgtgcc gatcgtaccg ggttcacaag gaattataga aaatgtggaa
     5401 gaagcggttt cacttgctaa tgaaattggg tatcctgtaa ttataaaagc cacagcaggc
     5461 ggaggcggaa aaggaatcag ggttgcccgc accgaagagg aactgattaa cggcattaag
     5521 attacccagc aggaagctgc aactgcattt ggaaatccag gtgtttacat cgaaaaatac
     5581 atagaggatt ttcgtcatgt tgagatccaa gtgcttgccg ataactacgg aaataccatc
     5641 catttagggg aacgtgactg ctcgatccaa agacgcctgc aaaagctttt ggaagaatca
     5701 ccatctcctg cgcttgattc agaaattagg gagcagatgg gcgatgcagc ggtaaaggct
     5761 gcaaaagcgg ttggctatac aggtgctgga acagttgaat ttatatatga ctacaatgaa
     5821 cagcgctatt acttcatgga aatgaacacg agaattcagg tagagcaccc agtcacagaa
     5881 atggtgacgg gaactgacct gattaaggaa caaatcaaag tggcatcagg aatggaactg
     5941 agcctcaagc aagaagatgt tgaatttgaa ggctgggcca tcgaatgccg aatcaacgca
     6001 gaaaatccaa gtaaaaattt catgccgtca cctggtgaaa ttaaaatgta cctgcctcct
     6061 ggtggtcttg gtgtccgtat cgattcagct gcgtacccgg gctactccat ccctccgtac
     6121 tatgacagca tgattgcaaa agtgatcaca tacggaaaaa cgagagatga agcgattgcc
     6181 cgcatgaagc gcgcattgag cgaatttgtc atcgaaggca ttgagacaac aatcccgttc
     6241 cacttaaaac tgcttgaaca cgaaacattt gttggcggag agtttaatac aaaattttta
     6301 gaaacatatg atgtaatggg ctcataattt ttacggaggt gaattgaatg aaagacaaca
     6361 gcttgcttaa aatggatcaa gaagatacgc atttgggtaa ggttgagatt gccccggaag
     6421 tcattgaggt cattgccggc attgcagctt cagaagttga cggtgttgcc gaaatgcgcg
     6481 gaaactttgc gacaggcgtc gtcgaacgct tcggtaaagt gaatcatggc aaaggtgtca
     6541 aagtcgacct ggcggatgat ggaattacga tcgatgtata ctgtgtcgtt acatttggtg
     6601 tttcgattcc gaaagttgca gcgtccgttc aggaaaacat tcgtcaaacc ttattaaata
     6661 tgacgtctct ttcgattaat gaaatcaata ttcacatcgt cggcattcaa tttgacacaa
     6721 aagcccagga agtccaaatc gacgaagaaa tgtaaatggc ttaacacgaa accaagggga
     6781 gggcggccct ttggtttttt tacacgttac cctttatttc aaagcatgaa gaaagccggc
     6841 tcaaggcagc cgagtttctt catgatcgtg aaatccgaat gatcatatta aggtgcatga
     6901 aaatattcgg taatagggtg aaaaaacctt gatttcaata tgcggatacg aaaaaaatat
     6961 gttatgatct ctttgtggct taacgacaag cggataaaga ggatcaaagg agaaagaaaa
     7021 tgaaaagaag aacagcaaga gaaaaagctt tgcaggcact atttcaaatt gatgtcagcg
     7081 atattgcagt gaatgaagcc atagaacacg cactggatga agaaaaaaca gatcctttct
     7141 ttgaacagct tgtacacggg gtattggaac atcaagtcca gctggatgaa atgatctcca
     7201 agcatctggt gaattggaag ctcgatcgga ttgccaatgt tgaccgcgcg attttgcgtc
     7261 tggcagctta cgaaatggca tatgccgaag atattccggt gaatgtctcc atgaacgaag
     7321 cgattgagct ggcaaaacgg tttggtgatg acaaagcgac aaaatttgta aacggggttc
     7381 tttctaacat taaatctgat attgaccaat cataggagga aagaaaatga ctgcaacaat
     7441 catcgacgga aaagaaacgg ctagagaaaa acgcgaacaa ttggcaaaag aggtagaaga
     7501 gcttaaaaag caaggggtca cccccggact ggcggttatt ttgattggag atgatcctgc
     7561 ttctcactct tacgtgcgag gaaagaaaaa agcggctgaa acaatgggaa tgaatttcaa
     7621 gcttgatcaa tttgacagca gcctcacaga agctgaactg ctttccatta tcgatcaata
     7681 caatcaagac cctgagtttc acggcattct cgttcagctt ccgcttccag accatatttc
     7741 tgaaaaagcg gtgatcgaac gtatctctcc tgataaagat gtagacggtt ttcatccgtt
     7801 aaacgtaggg aaaatgctgc ttggcgaaga tacgtttctt ccttgcacgc ctcacggaat
     7861 tgttgagctt ttgaagaaaa ccaatatcga cctttccggt aaagaggttg ttgtagtcgg
     7921 ccgaagcaat attgtcggca aacctgtcgg ccagctttta ttaaatgaaa acgcgacagt
     7981 tacttactgt cattcaagaa cagaaaatat gaccgaacat acgaaaaaag cggacatcct
     8041 ggtggtcgca gtcggcagag ccaacttcat cagtgcagac cagatcaaag aaggcgctgt
     8101 tgtcattgac gtaggcgtta accgtctgga aagcggaaag ctttgcggag atgttgaatt
     8161 tgaaggggca aaggaaaaag catccttcat cacgccggtt ccgggcggag taggtccgat
     8221 gaccatcacg atgcttgcgc ataatactgt taaatctgcg aaacgtacgt tatcatagat
     8281 aattggagat attcacaggc ggggttttgc ccgccgtgaa tatgagcacg atacccgctt
     8341 cttcaggctc ctaaagccag ggcgggtttt ctttagttat ggtgcaggaa tgcttatgag
     8401 aggagtttga gacatgggtg aaacagcgtt tgttaccgtc tcagcgctga caaagtatat
     8461 aaaacgaaaa ttcgatgtag atcctcacct tgaaaatatt tggattaaag gcgaattatc
     8521 gaatgtaaaa atacacacaa gaggccacat ttatttcaca ttgaaagacg aaaacgccag
     8581 aatgcagtcg gtgatgttcg cgagacagag cgagcgtctg ccttttaaac ctgaaaacgg
     8641 catgaaggtg ctggtcagag gcggaatttc cgtatatgaa ccgagcggaa actaccaatt
     8701 atatgccaaa gaaatgcagc ctgacggggt cggagcactt tatttagcgt acgaagagtt
     8761 aaaaaagaag cttgccggag aaggtttatt tgacgaccgc tacaaaaaac aaatccccgc
     8821 atttccagcc acaatcgggg ttgtgacatc tccgacgggt gccgctgtta gagacgtcat
     8881 tacaactctc aaaagaagat atccccttgt aaaagtcctt gttcttccag cgctcgtaca
     8941 aggcgaaaat gcaagcagat ccatcgttag ccgcattgaa gaggcaaatg aaaaagagat
     9001 gtgcgacgta ttaattgtcg ggagaggcgg cggttcgata gaagaactgt gggcatttaa
     9061 tgaagaaatt gtagcacgtg cgatctttgc ttctaacatt ccgattatat cggctgtcgg
     9121 gcatgagacc gactttacga tcagtgattt tgtcgctgat attagagctg cgacaccgac
     9181 aggagcagct gagattgccg taccgcatac cactgattta atcgaacgga caaaaacagc
     9241 ggaagtcaga atgacaagag cgatgcagca gcatctcggt cagaaaaaag aacggattca
     9301 aacgctgcaa tcctcgtatg cctttcgttt tccaaagcgt ttgtatgcgc aaaaagagca
     9361 gcagtttgac cttgcctatc agcagtttca agcacagctt accgctcttt tagatcgaaa
     9421 aaacagacag ctggagcgtg aaacgtacag attagaggcg ctgcatccac atgaacagct
     9481 gaagcaagcg agaacacgat atgaggaaca aacaaatcag ctgagaaaaa atatgaatat
     9541 ccaaatgaag cagctgcatt cccaatttca aactgttctt ggcaagctga atgcgttaag
     9601 tcctcttcaa gtgatggaaa gaggatacag cttggcttat aaagaagacg aactcattaa
     9661 aagtgtcaat caaatagaag agaaggacca gcttgaggtc aagctgaagg atggcgtgct
     9721 gacctgtgaa gtattagaaa agagagggga agaaaaatga cagacgtgaa aaaaaatgaa
     9781 aacatgacat ttgaagaagc gatgaaaggg cttgagagca ttgtgtcaaa gcttgaagag
     9841 ggtgatgtgc ctttagagca agcgattaac tatttccaag aaggcatggc tctttcaaaa
     9901 atgtgtcacg aaaagctgca aaaagtcgaa aaacaaatgg acttcatttt aaaagaagac
     9961 ggcgaactgg cacctttcag tgttcaggag gaagacgaag gtgacaaata aattaacgag
    10021 ctttctggcg gagcggaaaa aaacgattga aaatcagctt tctgtctata cagaaaagct
    10081 cgatatgccg gactcattaa aaaaatctat gctgtattcc cttgaggctg gcggaaagcg
    10141 gctgcgtcct ctcattgtac tagccgtttt aaacgcatat gggaaaagtg aaaaggacgg
    10201 cattccggtc gggtgtgctg tcgaaatgat tcacacgtat tcattgattc atgatgacct
    10261 tccttgtatg gatgatgacg atttgcgccg cgggaagccg acaaaccata aagtgttcgg
    10321 tgaagcgaca gcagtattag cgggtgacgg gctcctgacg gaaagtttta agctgatcac
    10381 ctcccacgtg tcagacgagg tgtcagcaga aaagcgcctt cggcttgtga atgagctgat
    10441 ttcagcggca ggcactgaag gcatggtcgg gggacaagta gctgatatgg aagcggaaaa
    10501 ccgccaagtc acgcttgaag aactcgaatc cattcatgaa cggaaaaccg ccaagctcct
    10561 tggttttagc gtaatcgccg gtgctatttt ggcggatgcg cctgaggaag atatcgaaac
    10621 gctgcgtacc ttcagcagcc acattggaat cggttttcaa atcagagacg atattttaga
    10681 tttagaaggc agtgaagaga aaatcggcaa acgtgtcggc tcggatacaa caaacgaaaa
    10741 atcgacttac ccgtcacttc tttcactgga aggggccaaa cataaattgg atgttcacat
    10801 aaaagaggcg aagcgtttga tcggcggact ctctcttcaa aaagaccttt tatatgagct
    10861 ttgtgattta attgcggcaa gagatcacta aaccgatcct aatttgaagc ggctgcacga
    10921 gatatggtaa aatgtaagca gtttatatga aaaatgaaaa ggaaaagcgc gtttgtcttt
    10981 ttttatgtct gagatctggc tgttgtccag ctcgacatgc agaagacatg tatcattgca
    11041 gaaattcatg ctgaaagtga gttgatccgc tttggatctt ttatcaatac aggacccgtc
    11101 gtttttaaaa aacatgtcca ttgatgaatt agagaaatta agtgatgaaa tccgtcaatt
    11161 tttaattaca actttatccg cttccggcgg ccacatcggc ccaaacttag gtgtcgtaga
    11221 gcttactgtt gcgctgcata aggaatttaa cagcccaaaa gacaaatttt tgtgggatgt
    11281 aggccaccag tcgtatgtcc ataagctgct gacaggacgc ggaaaagaat ttgcgacgct
    11341 tcgccaatac aaagggcttt gcggatttcc aaagcggagt gaaagcgagc atgatgtttg
    11401 ggaaaccggg cacagctcaa cttctctgtc aggcgcgatg ggaatggcag ctgcgcgtga
    11461 tattaaagga acggatgaat ttattattcc gattattggt gatggcgcgc tgaccggcgg
    11521 aatggcgctt gaagccttga accacatcgg cgacgagaaa aaagacatga ttgtcatcct
    11581 aaatgataat gaaatgagta ttgcaccgaa tgtcggtgcc attcattcta tgctcggaag
    11641 gctgcgcacc gccgggaaat accagtgggt caaagatgaa ctcgaatact tgtttaaaaa
    11701 gattccggca gttggaggca aacttgccgc cacggcggaa cggatcaaag acagcctgaa
    11761 atacatgctc gtctccggaa tgttttttga ggagcttggt tttacgtatt taggcccggt
    11821 ggacggacat tcttatcatg agctgattga gaatcttcaa tacgccaaaa aaacgaaagg
    11881 ccctgttctc ctgcatgtca tcacgaaaaa agggaagggg tacaaaccgg ctgagaccga
    11941 tacgattgga acatggcacg gtaccggacc atataaaatc aatactggtg actttgtaaa
    12001 accgaaagca gcagctcctt catggagcgg ccttgtcagc ggcactgtgc agcgaatggc
    12061 gcgcgaggac ggacgcattg tagccattac gccggctatg cctgtcggct caaagctaga
    12121 aggcttcgca aaggaattcc ctgaccgaat gttcgacgta ggaatcgcag aacagcatgc
    12181 cgcaacgatg gctgcagcaa tggcaatgca ggggatgaag ccgtttttgg cgatttattc
    12241 aaccttcctg caaagggcat atgatcaagt ggttcatgac atttgccgcc aaaacgccaa
    12301 tgtgtttatt ggaattgacc gtgcaggact cgtaggtgct gacggtgaga cacatcaagg
    12361 tgtgtttgat attgcgttta tgcgccacat tccaaacatc gtcttaatga tgccgaaaga
    12421 tgaaaatgaa ggacagcata tggttcatac agcactcagc tatgacgaag gcccgattgc
    12481 gatgcgtttt ccgcgcggaa acggactcgg cgtaaaaatg gatgaacagc tgaaaacgat
    12541 tccgatcggt acgtgggagg tgctgcgtcc agggaacgat gcagtcatct taacattcgg
    12601 tacaacaatc gaaatggcgc ttgaagcagc cgaagagctg cagaaagaag gactctccgt
    12661 gcgcgttgtg aatgcgcgtt ttattaagcc gattgatgaa aagatgatga agagtatcct
    12721 aaaagaaggc ttgccaattt taacaattga agaagcggtc ttagaaggcg gtttcggaag
    12781 ctcgatttta gaattcgctc atgatcaagg tgaatatcat actccgatcg acagaatggg
    12841 tatacctgat cggtttattg aacacggaag tgtaacggcg cttcttgagg aaattggact
    12901 gacaaaacag caggtggcaa atcgtattag attactgatg ccgccaaaga cacacaaagg
    12961 aattggatca tgacgtcaaa gaaagaacga ttagatgtat tattagtgga aagagggctg
    13021 gcggaaacgc gtgaaaaagc caaaagagcc attatggcgg ggatcgtcta ttcaaacgaa
    13081 aaccgcttgg acaagcctgg agaaaaaatt gatcgcgacc ttccgctaac agtcaaagga
    13141 aacccgctga ggtatgtgag caggggcggc ttaaagctcg aaaaagcgtt gaaggaattt
    13201 cccgtctctg tcaatgataa aattatgatt gatattggct cctccaccgg cggttttacg
    13261 gactgcgctt tgcaaaatgg agctaaacag tcatacgctg tggatgtagg ctataatcag
    13321 cttgcgtgga agcttagaca ggatgaacgg gtcgtcgtga tggaacggac gaactttcgt
    13381 tatgcaacac cggcagactt tacaaagggc atgccggagt ttgccacaat tgatgtgtcc
    13441 tttatttcac tgcggctcat cctgcctgtc ctcaaaacat tactcgtacc gggcagcgac
    13501 tgcatggctc tagttaagcc tcagtttgaa gcgggacggg aatccgtcgg caaaaaaggg
    13561 attgtcagag atcctaaagt gcatgtggat gttctcaagc gaatgaatag tttctctgcg
    13621 gatgaaggct atatttgcaa aggcctgtca ttttctccaa tcacaggagg agacggaaat
    13681 attgaatttc tccttcattt gcattggccg ggagagggac aggaaggaca agagctgccg
    13741 gaagaagaga tcatccgcgt tgtagaagag gcacataaga cgttaaaaga aaaaaaagca
    13801 gatgtaccgg aataataggg cgctattatt ccttttttct gcattcatgt acaatttgca
    13861 gagaatcata taacataaaa gaacagataa gctggaaata gaggtgctta catgaacaaa
    13921 ggccagaggc atattaaaat cagagagatc attacaagca atgaaatcga aacgcaggat
    13981 gaattggtcg acatgctgaa gcaggatgga tacaaagtaa cacaagccac ggtttcacgg
    14041 gatatcaaag aacttcacct tgtgaaagtg cctacgaata acggctctta caaatacagt
    14101 cttccggcag accagcgttt caatccgttg tccaagctga agcgggcatt gatggacgca
    14161 tttgtgaaaa tagactcagc aagccatatg attgtgctga aaacgatgcc gggaaacgcc
    14221 caggcaatcg gagcgctgat ggacaattta gactgggatg aaattatggg aaccatttgc
    14281 ggagatgaca cgattttaat tatttgccgg actcctgaag atacagacgg cgtaaaaaac
    14341 aggctgcttg agctgctgta acagaaatct aacaaagata agaggtgtaa tgctgtttgt
    14401 tagctgaact atcgattaaa aactttgcca ttattgagga actgacggtt tcttttgaac
    14461 gagggctcac ggttttaaca ggagaaaccg gagccggcaa atccatcatc atagacgcca
    14521 tttctctttt agtcggaggc cgcggatcat ctgaatttgt cagatatgga gagacaaaag
    14581 ccgagcttga agggctgttt ctattggaga gcggccaccc cgtttttgac gtatgcactg
    14641 agcagggaat cgacgtttca gacgaaatga tcgtcatgag aagggatatc agctcgagcg
    14701 gaaaaagcgt ttgccgtgtt aatggcaagc ttgtcacgat tgcttcgtta agagagatcg
    14761 gcaggctttt attagatatt cacgggcagc acgataacca gctgttaatg gaggacgaaa
    14821 atcatctcca gcttttggac aagtttgccg gagccgaagt agaaagcgcg cttcaagcat
    14881 atcaggaaga gtaccatcgg tatatgaagc tgcttaaaaa gctaaaacag ctttctgaaa
    14941 gcgaacagga aatggcccat cgcctggacc ttattcaatt tcagctcgaa gaaatcgaat
    15001 cggcaaagct cgagcttaat gaagatgaac agctccaaga agagcgccag caaatttcaa
    15061 actttgagaa gatctatgaa tcgctgcaaa atgcatataa cgcgcttcgc agtgagcagg
    15121 gcggactgga ctgggtcgga atggcatcag cgcagctcga agatatatcc gatattaacg
    15181 aaccgctgaa aaaactgtct gaaagtgtgt cgaactctta ctatctgctg gaggacgcta
    15241 catttcagat gagaaatatg ctggatgagc ttgaatatga cccggaacgc ctgaattata
    15301 ttgagacgcg tcttaatgaa atcaaacagc tgaaacgaaa atacggtgca actgttgagg
    15361 agattttgga atacgcctct aaaattgaag aagagattga ccaaattgaa aacagggaca
    15421 gccatcttca aagcgtgaag aaggagcttg actcagtcgg caaagatgtt gcggtggaag
    15481 cggcaaatgt ttcacaaatc cggaaagcat gggcgaaaaa gctggccgat gagattcatc
    15541 gagaattaaa aagcctctat atggaaaaat caacttttga tacggaattt aagatcagaa
    15601 cagcgtctcg caatgaggag gcgccgattg taaacggcca gcctgttcag ctgactgacc
    15661 aaggaattga tctggtcaag tttttaattt caaccaacac aggcgagcct ttgaaatccc
    15721 tttcgaaagt cgcttccgga ggggagctgt cccgggtgat gcttgccatc aaaagcattt
    15781 tttcctcaca gcaggatgtg acgtcgatta tattcgatga ggtagatacc ggtgtaagcg
    15841 gcagagtcgc gcaggcaatc gctgagaaga tccataaagt ctcaatagga tcacaagtgc
    15901 tgtgtattac acacttgcct caggtagctg ccatggccga tacgcatctt tatattgcga
    15961 aggagttaaa agatggcaga accacgacac gtgtcaagcc gctgtctaag caggaaaagg
    16021 tagtggaaat cgggcgcatg attgccggag tcgaagtaac agacttgacg aaacgccatg
    16081 cgaaagaact tctaaaacaa gcggatcaag tcaaaacaac tgggtaagct gcgcgagaag
    16141 cgcagcttat ttttttcgcg cacatccatt cgttcatcag tatatccaat gtttttcttt
    16201 atatgacagt tataaataag gtgtcagaag gcaaaattaa agatgtagca gcaagacata
    16261 aagaaggtgt gggataggag cgaggagagt gaagtagtga atgcccgata acatcagaaa
    16321 agcagtaggt ttaattctcc ttgtttcgtt attaagtgta ggtttatgca aaccgctaaa
    16381 agagtattta ctgattccaa cgcaaatgag agtatttgaa acccaaacac aagcgattga
    16441 aacaggttta tcagtaaacg ctcatgcaca agaatcatca gaagcgttta cagtaaagaa
    16501 agacccgcat gaaattaagg tgacaggcaa aaaatcaggt gagtcagagt tagtatacga
    16561 tcttgccgga tttccaatca aaaaaacaaa agtgcaggtt cttcctgatt taaaggtcat
    16621 acctggcgga caatcaatcg gtgtaaagct tcattccgtc ggtgttcttg tcgtcggatt
    16681 tcatcaaatc aatacaagtg aaggcaaaaa atctccggga gaaacggccg gtattgaagc
    16741 gggcgacatc attattgaga tgaatggaca gaaaattgaa aaaatgaatg atgtggcccc
    16801 atttattcag aaagccggta aaaccggaga atccttagat ttgctcatta aacgtgacaa
    16861 acaaaaaatc aaaacaaagc tcattccgga aaaggatgaa gcagaaggca agtacagaat
    16921 tggtttatac atcagggatt ctgctgctgg catcggcaca atgacttttt atgaaccgaa
    16981 aacaaaaaaa tacggagcac ttggccacgt gatttctgac atggacacaa agaaaccaat
    17041 cgtagtggaa aatggagaaa ttgttaaatc aactgtaaca tccattgaaa aagggacagg
    17101 cggaaatccg ggagaaaaac tggcgcgatt ttcctcagaa cgcaaaacga tcggggatat
    17161 taacagaaac agcccatttg gcattttcgg cacactgcat cagccgattc aaaacaacat
    17221 ttcagatcaa gcactgccgg ttgcgttttc tactgaagtc aaaaaagggc ctgctgaaat
    17281 tttaacggtc attgatgatg acaaggtaga aaagtttgat attgaaatcg tcagcacaac
    17341 accgcaaaaa ttcccggcga caaaaggaat ggttttaaaa ataaccgatc caagactgtt
    17401 gaaagaaaca ggcggcatcg tacaggggat gagcgggagt ccgatcattc aaaatggaaa
    17461 agtgatcggc gctgtcaccc atgtgtttgt aaatgacccg acaagcggct acggcgttca
    17521 tattgaatgg atgctgtcag aagcaggaat cgatatttac gaaaaagaaa aagcaagctg
    17581 actgccggta tttccggcag tttttttgtt ttgatccctc ttcacttctc ggaatacata
    17641 cggtaaaatg tacaaaagaa gatttttcga caaattcacg tttccttgtt tgtcaaattt
    17701 catttttagt cgaaaaacgg agaaaaacat agaataacaa agatatgcca ctaatattgg
    17761 tgattatgat tttttttaga gggtatatag cggttttgtc gaatgtaaac atgtagcaag
    17821 ggtgaatcct gttaactaca tttggggagg aagaaacgtg gagaaaatta aagtttgtgt
    17881 tgctgacgat aatcgagagc tggtaagcct gttgagtgaa tatatagaag gacaggaaga
    17941 catggaagtg atcggtgttg cttataacgg acaggaatgc ctgtcgttgt ttaaagaaaa
    18001 agatcccgat gtgctcgtat tggatattat tatgccgcat ttggatggac ttgcggtttt
    18061 agagcggctg agggaatcag atctgaaaaa acagccgaat gtcattatgc tgacagcctt
    18121 tggacaggaa gatgtcacga aaaaggccgt cgatttaggc gcttcctact ttattctcaa
    18181 accgtttgat atggaaaacc ttgtcggaca tatccgccaa gtcagcggaa atgccagcag
    18241 cgtgacgcat cgtgcgccat catcgcaaag cagcattata cgcagcagcc agcctgaacc
    18301 aaagaagaaa aatctcgacg cgagcatcac aagcattatc catgaaatcg gcgtcccagc
    18361 acatattaaa ggctatctct atctgcgcga agcaatctca atggtataca atgacattga
    18421 attgctcggc agtattacaa aagtcctcta tccggacatc gccaaaaaat tcaacacaac
    18481 cgctagccgt gtagaaagag cgatccgcca tgcgatcgaa gtggcatgga gcagaggcaa
    18541 cattgattcc atttcctcgc tgttcggcta tacagtcagt atgacaaaag ctaagccgac
    18601 aaactcagag ttcattgcga tggttgcgga taagctgaga ttagagcata aggcttctta
    18661 agcatgagca tattaactga tgattaaatc aaacgtcttt tatttattag tttgcgctga
    18721 taaataggag gcgttttgtt ttggggacat ttgtttcatg ggtgatgaat atgaaggatc
    18781 tattttccgc aaggaggagt gatacaggtg tttgaaaaat acggactgct gatggcgtta
    18841 tttatcctgg cgctttgcgt caattcaaac atcatgacag aatcacacat actaagcacc
    18901 ctgattgact ttatttcatt tgcagtcatg gtttcatgtg ttttcgctgc ttggatcata
    18961 aaaaacaaac aatcgggatc aaattgaaac cttttccctg taaaatcgta agtaaggaag
    19021 cattcatgaa caaaggagat gtacgaatga aaaagaaaaa agcaagaaag cgtgacgggc
    19081 ttctcctaga tttgcttccc caagcagctg gcgagctcct tctcctgctg tttagatgtt
    19141 tacataaatt atttatttaa agttgaaaaa agactgccga atcgtttcgg cagtctttgc
    19201 acattaatct ttataaggca cccagccagg tgtgttcaca attgcttgcc atagcggttc
    19261 aggcaagtga tatttttctt tgtcagtgcc ttttatcacg gtttcaattt gtttttcccg
    19321 gccttctttt actttcactg tccagtcagg gtcaactaaa atttcgcgtc ccaaagcgac
    19381 tagcggaata ccgttttcga tcacagccag tgcgtcatct gcggaatgaa tggaaccgac
    19441 ggcgataagc ggcactttgt ttccgacacg ttcattcaat aagtccatgc gtgtgcgagt
    19501 cggatctgca ccgcggcgcg cttttgagtt cacgtccatc agtgagatat gaaggtaatc
    19561 caattcttta tctcctaaag cgtcaacaag cgtaaaggtt tcagtcattg ttaatcctgg
    19621 tgtctcaggt tcttccggag acaggcgata gccgactaag aacgcaccct tcgcatgttc
    19681 tgcagcagct tttttcactt catcgacaat agcaagcggg aaggctaatc gtttttcgtc
    19741 gcttcctccc cagcggtctg tgcgctgatt ggttttcgga gaataaaact gctgaatcaa
    19801 gtagccgttt gcgccgtgaa tttcgacacc gtcaaagccg gcttcaatgg cacgtcttgt
    19861 cgcttctcca aatgctttca cgatgttttc cacttcttcg tctgttaagg cgcgggcaat
    19921 ttgcttgccg tcatcaaaca cgtcacttgg cgctacaact tcttgttgcg gaacgagctc
    19981 agacgggcat tcaatgccgc cgtgatgaat ttgcacaaca gctttagcac cttgcgcctg
    20041 aatcgcttgc gctagttttt ttaaacctgg aatgttggag tcatcatgga tggccggctg
    20101 cccgggaaat gcttttccgt ccggcgtgac gtttgcgcag gctgtaatca ccattcccat
    20161 ctcttttgag cgggggatga tgtagtcaag ctctgcttca gatatcgtac cgtcttcatt
    20221 agaagcgtaa tgagtcattg gtgctactgt gatccggttg tcgattgtaa cgccgctttt
    20281 aaatgtaaat ggttcaaaca gcggtttata cttagggttc atttgatcat cttctttcgt
    20341 ttggattcgc acatattcta gcctatatgt aaaaattaat gcaattgatc tgctttaccg
    20401 gctgaatatc ttgaaaacag agtgatgttt tctgcgctct ttttcggggg ctttgtagcc
    20461 gccgctgatt tggtggccga tggtgcaatt ggtgacacgc tgcagcgagc aacagacatg
    20521 gctgtaactt ctctctgtaa agtgaatatc ctttaaaagg ttacgcctgg ctgatccact
    20581 cgtcaaacga tttgctcaca tcattcctca aattttttaa aatgaataaa aagttgcttc
    20641 tttccgttaa ttttttctaa tatgcgcctc aattagagcc atcctcatag acaaatgcga
    20701 ttgctttctt tctaacaaca ggaaatgatc aggtcggata gcccttttga aaaatgtgga
    20761 atccagtgcc gtctttcgcg tcggctttac aaatctgcca ttctggtcaa agataaaagc
    20821 caaacatcag gaagaggtga tcatgtgaaa caagcggctc ttttgctgtt tactgtgctg
    20881 tttctctcag g
//
