LOCUS       NZ_MOOT01000054        24394 bp    DNA     linear   CON 20-MAY-2024
DEFINITION  Bacillus thuringiensis serovar dakota strain BGSC 4R1 contig000054,
            whole genome shotgun sequence.
ACCESSION   NZ_MOOT01000054
VERSION     NZ_MOOT01000054.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis serovar dakota
  ORGANISM  Bacillus thuringiensis serovar dakota
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 120437)
  AUTHORS   Zheng,J., Gao,Q., Liu,H., Peng,D., Ruan,L. and Sun,M.
  TITLE     Comparative genomics of Bacillus thuringiensis reveals a path to
            pathogens against multiple invertebrate hosts
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 120437)
  AUTHORS   Zheng,J., Gao,Q., Liu,H., Peng,D., Ruan,L. and Sun,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-OCT-2016) State Key Laboratory of Agricultural
            Microbiology, Huazhong Agricultural University, 1st Shizishan,
            Wuhan, Hubei 430070, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABySS v. 1.5.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002148095.1-RS_2024_05_20
            Annotation Date                   :: 05/20/2024 01:21:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,175
            CDSs (total)                      :: 6,055
            Genes (coding)                    :: 5,836
            CDSs (with protein)               :: 5,836
            Genes (RNA)                       :: 120
            rRNAs                             :: 4, 7, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 7, 6 (5S, 16S, 23S)
            tRNAs                             :: 98
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 219
            CDSs (without protein)            :: 219
            Pseudo Genes (ambiguous residues) :: 0 of 219
            Pseudo Genes (frameshifted)       :: 88 of 219
            Pseudo Genes (incomplete)         :: 138 of 219
            Pseudo Genes (internal stop)      :: 66 of 219
            Pseudo Genes (multiple problems)  :: 56 of 219
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:21:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 71163
            Orig. end                         :: 95557
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MOOT01000054.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24394
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="2"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24394
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24394
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14394](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14394
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    121..136
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.01"
                     /tool="antismash"
     misc_feature    322..338
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.87"
                     /tool="antismash"
     misc_feature    592..608
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.87"
                     /tool="antismash"
     gene            1779..3476
                     /locus_tag="BK765_RS17650"
                     /old_locus_tag="BK765_16755"
     CDS             1779..3476
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016136171.1"
                     /locus_tag="BK765_RS17650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16755"
                     /product="hypothetical protein"
                     /protein_id="WP_000369377.1"
                     /transl_table=11
                     /translation="MDNLLQMFRDALLISEPIYKTNELVWNKWNAYFKDVENNNNKVLT
                     SPHASPSFTALVSWLEKKQESGITLLQIYAKIDSYKEEIYKEIEVFIEKEFQNVVHTNS
                     LILENDQNIDKPNIVNHEDYYEVNNSAVYYKLRDGIAKNQFEEDEISKVLQYPIETRSS
                     NGVAQLSSHKDEDLRLTNIEEAARWNTLVDDVMSNMDDLTADCLDAITIQWINEAKSPD
                     DFIDFSYEQVLEMCNIPKTVVKNKEYYRAEDKIKIAKRIAALASIFIYLNDENEVVVLN
                     DRDDDGERLELKREVIKRLFVLDSVVLWRHSVTNEYMGIESCRIKPGSFLTNYLYGSNN
                     TTALLSKKALEYNSYRHKYHKRLIRYLTWQWRIRQMYSSLKKPYSIGGDKGLLAVMDIP
                     KDWKPNRIREQLENVLMDLENEKVISHWEYSDPLDEQQIGKRNWFKNYYTNLGITILPP
                     EEMLQSMDRVIGKKSIEEPQEQLPEVTVVKEIKKTVESVEQIEKKIRDQILKVHNEKKV
                     SIREIADEISISPSTLSRFCNYKTKRLSKKALEKLTKWCERQEILEKM"
     gene            complement(3638..4105)
                     /locus_tag="BK765_RS17655"
                     /old_locus_tag="BK765_16760"
     CDS             complement(3638..4105)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016090253.1"
                     /locus_tag="BK765_RS17655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16760"
                     /product="RsfA family transcriptional regulator"
                     /protein_id="WP_086398125.1"
                     /transl_table=11
                     /translation="MVISRQDSWTDDNDLLLASTVLQNIRNGGTQLAAFKEVAKLLART
                     PAACGFRWNSYVRKQYQEEIQQAKQDRKMGNNIPLSPSEKERNSLSITLDDIILFLQNY
                     KDVNELTKLQNQIEDLETENQSLLQRITMYEEEYRMLLNHIDKTRNLIAVD"
     gene            4460..6109
                     /locus_tag="BK765_RS17660"
                     /old_locus_tag="BK765_16765"
     CDS             4460..6109
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688773.1"
                     /locus_tag="BK765_RS17660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16765"
                     /product="S8 family peptidase"
                     /protein_id="WP_086398126.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 5.6e-24, bitscore:
                     77.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIFKGILVSSIALTAFNGVGGLLPSEKSEVAYAATYNYTNKQLN
                     STVHKQVNKQLILKFKNEANLPYQDGIEKFIKEEKQDPELIEILAEYPNVTINRLFNSL
                     NPKEIKNLGKEIKDSDHISSNLLSYYIVETQDDIDVQALLTKIEKSSLVETAYLQEEEA
                     PPAERLPNLSVNPYDEPRLTRQGYLEPAPLGINAPYAWSIKGGDGKGTTFVDMEYGWLF
                     SHEDLVNQKIELISGQNKSEHHDHGTSVLGIVSAEDNNIGGIGIAPKAKVKVVSQIRDN
                     GNYNTADAILSAVNNMQAGDILLLEAQATYDGYGDKNYFPVEVKPDIFDAIRMGTNKGI
                     IIIEAGANGGNDLDQFRDRNGKQVLNRNSPDFKDSGAIMVGAASARVPHKRSYFSNYGS
                     RVDVYGWGNAVDTTDAKPSEFITNLYTSSFAGTSSASPIIAGAAASIQGIVKNNQGRVY
                     TPRQLRAILSDSSTGTKSNDPTSDKIGVLPDLKAILSKLGFSPNLSNDSSIAFPEEQEI
                     NKGNKGNEGSTITFPKEDSANGEGDSSFIFPE"
     misc_feature    6433..6448
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 24.41"
                     /tool="antismash"
     gene            6713..6868
                     /locus_tag="BK765_RS17665"
                     /old_locus_tag="BK765_16770"
     CDS             6713..6868
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Antimicr18"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031158.1"
                     /locus_tag="BK765_RS17665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16770"
                     /product="type A lantibiotic"
                     /protein_id="WP_001031159.1"
                     /sec_met_domain="Antimicr18 (E-value: 7e-10, bitscore:
                     31.6, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKELFDLDINKKMETPTEMTAQTVPTTIFVSRSVCKTLTCICTI
                     SCSNCK"
     CDS_motif       6713..6787
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNKELFDLDINKKMETPTEMTAQTV"
                     /locus_tag="BK765_RS17665_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6788..6868
                     /prepeptide="core"
                     /locus_tag="BK765_RS17665_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="10.10"
                     /molecular_weight="2647.2"
                     /monoisotopic_mass="2645.4"
                     /core_sequence="PTTIFVSRSVCKTLTCICTISCSNCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNKELFDLDINKKMETPTEMTAQTV"
                     /leader_location="[6712:6787](+)"
                     /alternative_weights="2665.2"
                     /alternative_weights="2683.2"
                     /alternative_weights="2701.3"
                     /alternative_weights="2719.3"
     gene            7255..7410
                     /locus_tag="BK765_RS17670"
                     /old_locus_tag="BK765_16775"
     CDS             7255..7410
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Antimicr18"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031158.1"
                     /locus_tag="BK765_RS17670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16775"
                     /product="type A lantibiotic"
                     /protein_id="WP_086398127.1"
                     /sec_met_domain="Antimicr18 (E-value: 3.3e-10, bitscore:
                     32.7, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKELFDLDINKKMEASTEMTVQTWGTVVKVSKAICKTGTCIGTI
                     SCTNCK"
     CDS_motif       7255..7329
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNKELFDLDINKKMEASTEMTVQTW"
                     /locus_tag="BK765_RS17670_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       7330..7410
                     /prepeptide="core"
                     /locus_tag="BK765_RS17670_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="9.90"
                     /molecular_weight="2490.0"
                     /monoisotopic_mass="2488.3"
                     /core_sequence="GTVVKVSKAICKTGTCIGTISCTNCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNKELFDLDINKKMEASTEMTVQTW"
                     /leader_location="[7254:7329](+)"
                     /alternative_weights="2508.0"
                     /alternative_weights="2526.1"
                     /alternative_weights="2544.1"
     gene            7690..7845
                     /locus_tag="BK765_RS17675"
                     /old_locus_tag="BK765_16780"
     CDS             7690..7845
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Antimicr18"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031158.1"
                     /locus_tag="BK765_RS17675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16780"
                     /product="type A lantibiotic"
                     /protein_id="WP_000356689.1"
                     /sec_met_domain="Antimicr18 (E-value: 9.5e-09, bitscore:
                     28.0, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKELFDLDINKKMETPTEMTAQTWTSILKVSRAPCKSGTCLCTT
                     SCSNCK"
     CDS_motif       7690..7758
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDKELFDLDINKKMETPTEMTAQ"
                     /locus_tag="BK765_RS17675_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       7759..7845
                     /prepeptide="core"
                     /locus_tag="BK765_RS17675_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="10.10"
                     /molecular_weight="2799.3"
                     /monoisotopic_mass="2797.4"
                     /core_sequence="TWTSILKVSRAPCKSGTCLCTTSCSNCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDKELFDLDINKKMETPTEMTAQ"
                     /leader_location="[7689:7758](+)"
                     /alternative_weights="2817.3"
                     /alternative_weights="2835.3"
                     /alternative_weights="2853.4"
                     /alternative_weights="2871.4"
                     /alternative_weights="2889.4"
     gene            8218..8373
                     /locus_tag="BK765_RS17680"
                     /old_locus_tag="BK765_16785"
     CDS             8218..8373
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Antimicr18"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031158.1"
                     /locus_tag="BK765_RS17680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16785"
                     /product="type A lantibiotic"
                     /protein_id="WP_001031160.1"
                     /sec_met_domain="Antimicr18 (E-value: 5.2e-09, bitscore:
                     28.9, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKELFDLDINKKMETPTEMTAQTWTTIVKVSKAVCKTGTCICTT
                     SCSNCK"
     CDS_motif       8218..8286
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNKELFDLDINKKMETPTEMTAQ"
                     /locus_tag="BK765_RS17680_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8287..8373
                     /prepeptide="core"
                     /locus_tag="BK765_RS17680_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="10.10"
                     /molecular_weight="2787.3"
                     /monoisotopic_mass="2785.4"
                     /core_sequence="TWTTIVKVSKAVCKTGTCICTTSCSNCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNKELFDLDINKKMETPTEMTAQ"
                     /leader_location="[8217:8286](+)"
                     /alternative_weights="2805.3"
                     /alternative_weights="2823.4"
                     /alternative_weights="2841.4"
                     /alternative_weights="2859.4"
                     /alternative_weights="2877.4"
     gene            8735..8890
                     /locus_tag="BK765_RS17685"
                     /old_locus_tag="BK765_16790"
     CDS             8735..8890
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Antimicr18"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031158.1"
                     /locus_tag="BK765_RS17685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16790"
                     /product="type A lantibiotic"
                     /protein_id="WP_001031160.1"
                     /sec_met_domain="Antimicr18 (E-value: 5.2e-09, bitscore:
                     28.9, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKELFDLDINKKMETPTEMTAQTWTTIVKVSKAVCKTGTCICTT
                     SCSNCK"
     CDS_motif       8735..8803
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNKELFDLDINKKMETPTEMTAQ"
                     /locus_tag="BK765_RS17685_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8804..8890
                     /prepeptide="core"
                     /locus_tag="BK765_RS17685_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="10.10"
                     /molecular_weight="2787.3"
                     /monoisotopic_mass="2785.4"
                     /core_sequence="TWTTIVKVSKAVCKTGTCICTTSCSNCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNKELFDLDINKKMETPTEMTAQ"
                     /leader_location="[8734:8803](+)"
                     /alternative_weights="2805.3"
                     /alternative_weights="2823.4"
                     /alternative_weights="2841.4"
                     /alternative_weights="2859.4"
                     /alternative_weights="2877.4"
     gene            9014..9988
                     /locus_tag="BK765_RS17690"
                     /old_locus_tag="BK765_16795"
     CDS             9014..9988
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379742.1"
                     /locus_tag="BK765_RS17690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16795"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_086398128.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1e-32, bitscore:
                     106.3, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTIREKLSSYKPNIYCWNTSRLSEQFKTYDIEIGHPSIKIAILD
                     SGCDYLHSELNDNILINKSKSMIPYEENIEDYNGHGTAVISSIIGKKNVKGIAPAVSIL
                     SYKIVDKNGYGELRWTINAIKLAIQENVHIINISYTSNKIDDIDMIYEYKEVVKEAINK
                     GIYVICAAGNECKEIKQGSENLPIYLAEGIVIASTDYKGELSSFSNYGVGIDFSMPSGG
                     FSQGFPSQYGLVIVAKPRSMARLHLEDQYQVPKDYTLTMGTSISSALFSGTIALLLSRY
                     YRLYKKLPKRNEILSLVKLSGKQINRHYSMVEVNTYRALNEIK"
     gene            10001..13072
                     /locus_tag="BK765_RS17695"
                     /old_locus_tag="BK765_16800"
     CDS             10001..13072
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682666.1"
                     /locus_tag="BK765_RS17695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16800"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_086398129.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 8.9e-116,
                     bitscore: 380.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.4e-18,
                     bitscore: 58.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3e-26, bitscore:
                     85.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLLNTYMYRKPILTLKEYQELFDSKISTLEYENKIKEIFSDD
                     KLKLAIYISSPTMYEALNRLDSLDAKKKRNFLHGITKFLIRMSTRPTPFGLFAGMGIES
                     INNNGKGSFNIDSYFRLDFSTIYKIVEVLENQDEILKKANIRFNNLLYKHGNRLKLPYQ
                     SNVHNKDNIDEHMKIMTVKNSPVLDYIRKITRNDINFEQLVDKINKEFNTEDTTSKGYL
                     KKLIDNDILFSDLRPALSSNDPFKYLITILEEKNINHELLDNLKQINFSLDKFNLTKEE
                     ISVKELSNFKSLLKTFKLCGEKDIRVDAKLTNSSELALGDEDITNLEELSRIMSYLGCI
                     NPLQVLNSYRDSFIEKYGPYQEVPILELLDEDLGLGKPNDYVTNGNSQPQISENLRAVR
                     NLIQKWQTEALINNENIILDEDKIKEIKKHISRNDIEKENIDLELYFNYFQCKGANKFY
                     LVPNTGSTQIGNTYGRFKYMFNKNEINQLKDFNEFIEDQDSNIKFADLRINPDNSSLAN
                     IMNSPSVYKSEINLCTNPSESCSNNIDIENLVVGINNNKFYIRDSSSNNIIIPKISNMF
                     NYENANLIYRFLADVGALYSGIWGNIHHHFYDSHVYPKIVYKNIVVSPKRWIFHHTFTQ
                     KMSEEEFISVFLDWCTRNNITNYIYLAEYDNKLLLNIKNELHLSIIFQEFSKLKMNDRL
                     SLFECEEDIFVSSNKRFEECVFSFRQTDRKKITFTNSLNRNYQYINDMNRVKLLGSDWI
                     SLRVNYVDSRVEEFLSCGYKEFYKHNKDINKIEKGFFVRYADPTPHLRIRFKLSKNEKY
                     NTFLGNITEWLTNEREKGLVNDFHFVSYNPEIERYGNFLIDKAEDIFSIDSLIVADSFE
                     GDVPLNRELFCCLNIMSILKGFNLNFASQLEILNMAIDPKMYKEAYRENKANLDPIITN
                     IYDYIEIPMSEKLIIPTTFNDRDNVIRKYAELIDANEDVLTNVKSDIIASILHMHCNRL
                     NGINRDLENKILGMCYHTIKKYMNLIKYKYNVLV"
     aSDomain        10442..10714
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BK765_RS17695_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="9.60E-19"
                     /identifier="RREFam001.1"
                     /label="BK765_RS17695"
                     /locus_tag="BK765_RS17695"
                     /protein_end="238"
                     /protein_start="147"
                     /score="58.9"
                     /tool="antismash"
                     /translation="NNLLYKHGNRLKLPYQSNVHNKDNIDEHMKIMTVKNSPVLDYIRK
                     ITRNDINFEQLVDKINKEFNTEDTTSKGYLKKLIDNDILFSDLRPA"
     gene            13084..14394
                     /locus_tag="BK765_RS17700"
                     /old_locus_tag="BK765_16805"
     CDS             13084..14394
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083133.1"
                     /locus_tag="BK765_RS17700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16805"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_000152960.1"
                     /sec_met_domain="LANC_like (E-value: 2.5e-61, bitscore:
                     200.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIKLNENELKTLNEINQKLIKLYSDFEKVESYINDSASPGLEAI
                     ELASLAGGYAGIALALGVSDDVSSNQSTDEISYEYIKRCIAIIQSNPTYSFSLFSGLTG
                     ILISLKFNSKNGQRYKNIIEQLLQVITHNYKESLSISQANLINNTVTTDDFDVILGWSG
                     ILRTLLEFDNDLYDTELNKIIEDISLYLIKLGAFTNDSKPCWFIEYAQLSDIEKETFVG
                     GFYNNGMSHGISGVLASLSILYIKGYRFNGLESSINNIRTWLLQNILEHRGVEYIPNVT
                     VDNTNTFNHRDAWCYGTPGVSTALFISAMTDENLYIKEKSIELFKTFLKRASEEHKLIS
                     PTICHGFAGILMLCIRLIEYGVSDPEILEIANNVFQKLMSFYKENELILFPDYEIIENK
                     RVEIHKIGLLEGVTGIFLIIQSLLHDKNEWDQIFLIS"
     gene            14430..14981
                     /locus_tag="BK765_RS17705"
                     /old_locus_tag="BK765_16810"
     CDS             14430..14981
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016086949.1"
                     /locus_tag="BK765_RS17705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16810"
                     /product="DUF5823 family protein"
                     /protein_id="WP_086398130.1"
                     /transl_table=11
                     /translation="MIEILRTLVNFLIALFSGELPGIYYIWIIALLIVQIIQSTLNYNL
                     FNKKEKFSKYTMEGLLAFLIILIGSMLLSKLLAFIIEDSVINKTELTHYFVSLIVLTIF
                     VAIGCIKELIRHTIKNSNMSLVTFIIVSLIASILSFKLLLPLTGGSFTLSKSFINTLII
                     VVTGIIVLLVSMEEKYVDEE"
     gene            14971..16677
                     /locus_tag="BK765_RS17710"
                     /old_locus_tag="BK765_16815"
     CDS             14971..16677
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794843.1"
                     /locus_tag="BK765_RS17710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16815"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000794843.1"
                     /transl_table=11
                     /translation="MKNNSLIKTLKIVNWPIAKVIIAIFISIVSVFVSLLVPIYIKEII
                     DKIDFTNLPIKIILLVISFFIIASFLQGLSQYLLSYIGELTIRDLRKNMWEYIINLPVK
                     YYDNKETGQIMSRLIEDSSIVNNFVSMKLPIMLSQLILFFGALGLMIYMDWKITLFMLI
                     TVVVTTVIIIPLGNKIYVISTNHQQTIAEFSGILSRVLSDIRLVKIANAENLEIKRGND
                     KLERLFGLGIKQSKLYSFINPLITLIIMFTIIGILSYSGYRLSVGTLSTGTLVALLFYL
                     LQIIEPLTGLSSFFTDYKKTLGATDRIQEIYKNQLENKAGYAPSYEQDISFQNVSFSYG
                     EKEILKNVNFLAERNKVTAFVGPSGAGKSTIFSLLVKLYECQDGNIKYGDQSINNIDLT
                     LWRSKIGYAMQNAPVMNGTVLDNITYGLTRSYSMEEIHTVAQIANAHEFIMNLENQFDT
                     LVGERGILLSGGQKQRLALCRVFLHNPEILLLDEATSSLDSESEKHIERAINYVKSNKT
                     TLIIAHRLSTIMAADHIIFLDDGKITGQGTHEELLNTHERYRDFVTYQTIK"
     misc_feature    complement(16891..16907)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.71"
                     /tool="antismash"
     gene            17295..17702
                     /locus_tag="BK765_RS17715"
                     /old_locus_tag="BK765_16820"
     CDS             17295..17702
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016136174.1"
                     /locus_tag="BK765_RS17715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16820"
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000577227.1"
                     /transl_table=11
                     /translation="MIFQSMITAIIEKLQETVNPYWIIVFGSTAENREREDSDIDIAYV
                     SDTTLGNYERFLLAQELANIVHRDVDLVDLSEASTVFQAQIIHTGKTIFCSDEKRKVIF
                     EMKTLKMYSKLNEERQVVFEDIKKRGSIYEE"
     misc_feature    complement(17323..17339)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 25.92"
                     /tool="antismash"
     gene            17692..18105
                     /locus_tag="BK765_RS17720"
                     /old_locus_tag="BK765_16825"
     CDS             17692..18105
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002175020.1"
                     /locus_tag="BK765_RS17720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16825"
                     /product="DUF86 domain-containing protein"
                     /protein_id="WP_016093854.1"
                     /transl_table=11
                     /translation="MKNEVILNKISTIERCIKRIQDVYGNAPENLEDFTKQDSIILNIQ
                     RACEASIDLAMHIVAGKKLGLPQSSREAFDLLVTAGLLSADLANKLKAMVGFRNIAVHD
                     YQSVNLDIVRQIIEKHLTDFKLFTKEVMGILEF"
     gene            18522..18844
                     /locus_tag="BK765_RS17725"
                     /old_locus_tag="BK765_16830"
                     /pseudo=""
     CDS             18522..18844
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083130.1"
                     /locus_tag="BK765_RS17725"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16830"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIKKLIISSIALGATIGVSKPTFAATIHSPSQFKETRNVHVQSLY
                     SPWQYLGQTSRELQIKSKDPKVLAFELARNGLDLKKEIMNLNMKLKFLEIKNVSN"
     gene            complement(19563..20042)
                     /locus_tag="BK765_RS17730"
                     /old_locus_tag="BK765_16835"
     CDS             complement(19563..20042)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913866.1"
                     /locus_tag="BK765_RS17730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16835"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_086398131.1"
                     /sec_met_domain="Abi (E-value: 9.3e-16, bitscore: 50.8,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKKINRFMFALPTISFVFLILLGSFLFVIPLDLFLPEIQKNPIT
                     EAPLILQVLLGVLAAPIYETVIFQVFLFWLLSWIPYIKNRDYLIILIASIIFGLNHPYG
                     ITYIVGTTIIGLLYNYAYWVYKKKNEKYQVTMSAFWVVFLIHLLHNSIAFIASNL"
     gene            21236..22978
                     /locus_tag="BK765_RS17740"
                     /old_locus_tag="BK765_16840"
     CDS             21236..22978
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016078258.1"
                     /locus_tag="BK765_RS17740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16840"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_086398132.1"
                     /transl_table=11
                     /translation="MKKYWHKLSLLQKNVLLTVLLILTLVGSMGALSFNMFQNSMMSIF
                     ERQSFETGDAVLNQLDLEIVRDVAKDPTAQRVNKEKLTEQLDKAIKDMKSVGQTYVTGA
                     KLNDKAELQIVALDTELANTVSVKPGEYYEQPTYWMKTYDKVKQTKQAQMTEVYEDELG
                     FWVTILEPVTDENKNIIAIVAADLEASIIPLTKKNFMIQGLLFIIISLTIAITIQIFIS
                     RNSLSPLKDLQEGLRKVGEGDLSIKLNERPDDIGITNIYFNNTIKKFNRIIDKVRQTAE
                     QVSTSSQELSVSTKENSIAFKEIASAITGLNLGAHSHEYVVQKFLGIVQEMESKMKEIK
                     GAAKQVGNVSEDIEQHSVEGKDLIKQIVNQMKRIKDTVQDVSSSIYALEARSKEINEIL
                     TVITTISNQTNSLALDASTESSCAGEMGEEFPGVTDEVRILAERTEAPARDIAKLIGET
                     QTEAERAVRSIQKSSKEVELGIILVQSSGAFFEKISESAQSVTNQIKATSNHSSDILKD
                     NQTIVQFVNELSHIANTYVNSSSNVEKSMKEQELYVQDIAELANSLNWLSQELQGLIGE
                     FKNK"
     gene            23144..23359
                     /locus_tag="BK765_RS17745"
                     /old_locus_tag="BK765_16845"
     CDS             23144..23359
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167046.1"
                     /locus_tag="BK765_RS17745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16845"
                     /product="alpha/beta-type small acid-soluble spore protein"
                     /protein_id="WP_001167047.1"
                     /transl_table=11
                     /translation="MQIRENNNSNEILIAAAASAIEQMKYEIAQEFGVTLGPDSTARAN
                     GSVGGEITKRLVRMAQEQLSGQYKIH"
     gene            complement(23432..23848)
                     /locus_tag="BK765_RS17750"
                     /old_locus_tag="BK765_16850"
     CDS             complement(23432..23848)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733522.1"
                     /locus_tag="BK765_RS17750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BK765_16850"
                     /product="hypothetical protein"
                     /protein_id="WP_000733526.1"
                     /transl_table=11
                     /translation="MKKLILAGALGIAVLSGMNLPGAEASKASAATTNLEIQEVTKYYS
                     MSSYEVSQKESFNLKKGEELTVFVQNSGFPISYTVFDADNQVIGTFNANSPYGRVFKAQ
                     KDGNISVQFQAGVNSTYMKKMNFTAKFAVSKLNQ"
     misc_feature    23928..23943
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.06"
                     /tool="antismash"
     misc_feature    23928..23946
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 25.2"
                     /tool="antismash"
ORIGIN
        1 tatagctgta gtatttctcc tcaaatgttt ccacaaactt ttgccaagat ttgagtgtta
       61 ctaaaactgc gtttgttgtt ttcccattta agctacgttg attacgtatc acaaatgctt
      121 ttcccatctt tttcacctcc gttctacaaa ttcagaaata tatgtcaaaa tactataaaa
      181 tataccaatt ttgattatag caaaatgaaa attgctgaaa tgtgctcctt taagaagaaa
      241 attagtaact tgcaacagct tatgaagcta gttgtatcaa gggataagag aatttcatga
      301 tttttttttg tgttaaggat accgcaaacg tgttgcaagt tggatgatat gtataaaagt
      361 aagtgaaaaa gcaactaaac ccttggtata taaaggatta tagtgaaaat ggtagggaag
      421 ttagggaaag gataccgcaa acatgttgca agttagtaaa cgtaatcatt aaaaatgaat
      481 tgtaataatt acccttgata taaaaggact tgttgatatt tatagaatga aagtagggaa
      541 aggataccgc aaacagtgtt gcatcttgtg agaaaaataa gggcatgcat accgcaaacg
      601 tgttgcaagt tgggtaatat gtataaaagt aaatagaaaa gcacctaaac ccttggtata
      661 taagggatta cagtaaaaat ggtagagaag ttagggaaag gataccgcaa acatgttgca
      721 tattatgtat gtaacttatt aaaaatatga gataaatagc ttaaaaactt taaaatgaca
      781 tgattttttt taaaattatt tggttgagaa ataaattata ctgttgcaag ttgaaagaaa
      841 tagggaaagg ataccgcaaa catgttgcaa gttgattaga aataggtaag agaaagagca
      901 actgtgttgc aagttgaaga attaaggaaa gaaaggcgca aaaaaaatgc aggaagtaga
      961 aatagggaaa agaaagagca gcatgttgca agttgagaaa aataaggcaa acaaagcgca
     1021 aaaggaatgt aagtaagggg aaataggtaa gagaaagagc aaactgttgc aagttgaaga
     1081 gttaaggaaa gaaaggcgca aaagaaatgc aagtaagtag aaataggtaa gagaaagagc
     1141 aaactgttgc aagttgaaga gttaaggaaa gaaaggcgca aaagaaatgc aagtaagtag
     1201 aaatagggaa aagaaagagc agcatgttgc aagttaaaga gttaaggaaa gcaaagcgca
     1261 aaaagaatgt aagtaaggga aaagaggtaa gaggaagaac aacctgttgc aagttgaaga
     1321 gttaaggaaa gaaaggcgca aaagaaatgc aagtaagtag aaatagggaa aagaaagagc
     1381 agcatgttgc aagttgagaa aaataaggaa agcaaagcgc aaaagtttgc aagttgaaag
     1441 aaataggtaa gagaaagggc aaactgttgc aagttgagaa aaataaggaa agcaaagcgc
     1501 aaaagtgtgc aagttgaaag aaataggtaa gagaaagggc aaactgttgc agttgagaaa
     1561 aataaggaaa gcaaagcgca aaaggaatgt aagtaagtag aaataggtaa gaggaagagc
     1621 aaactgttgc aagttgagga gttaaggaaa taaatgtaag gaaagaaaga aacaaaaatt
     1681 tgtaaatatc tgttacaata aattaaatat aatagtagtt aagattttta tactaagaat
     1741 tattttattg tgatccatgg tttagggagg aaaagaaagt ggataactta ttacaaatgt
     1801 ttcgagatgc attgctaatc tctgagccaa tttataaaac taacgagcta gtatggaata
     1861 agtggaatgc atactttaaa gatgttgaaa ataataataa taaagtactc acatcacccc
     1921 atgcttctcc atcatttact gcattagtat cttggttaga gaaaaagcaa gagtctggaa
     1981 ttacattatt acaaatttat gcgaaaattg actcttataa agaagaaata tataaagaaa
     2041 ttgaagtatt tatagaaaaa gaatttcaaa atgtagtaca tacaaattct ttaatattag
     2101 aaaatgatca aaatatagat aagccaaata ttgtgaatca cgaggattat tacgaggtaa
     2161 ataactctgc tgtttattat aaattaagag atgggattgc aaagaatcaa tttgaagaag
     2221 atgaaataag taaggtctta caatatccca ttgaaacgag gtcttctaat ggtgtagctc
     2281 aactttcttc acacaaagat gaagatttaa gacttaccaa tatagaagaa gcagctcgat
     2341 ggaataccct tgtagatgac gtaatgagta atatggatga tttaacggca gattgcttag
     2401 atgcaatcac aatacagtgg attaatgaag caaaatctcc agatgatttt attgactttt
     2461 cgtatgaaca agttttagaa atgtgcaaca ttccaaaaac agttgttaaa aataaagaat
     2521 actatagagc ggaagataaa attaagatag caaagagaat tgcagcttta gcaagcattt
     2581 ttatctattt aaatgatgag aatgaagtcg ttgtattaaa tgaccgtgat gatgatgggg
     2641 aacgtttaga attaaagcgt gaagttatca aaagattatt tgtattagat tcagttgttt
     2701 tatggagaca tagtgttact aacgaataca tgggcattga atcttgtcgt attaagccgg
     2761 gtagcttttt aaccaattat ttgtatggat caaataatac aacagcccta ttatctaaaa
     2821 aagcacttga atacaatagt tatagacaca aatatcataa aaggttaatt cgatacttaa
     2881 catggcaatg gagaattaga caaatgtatt catcattgaa aaagccatat tctataggtg
     2941 gggacaaagg actgctagca gtaatggata tcccaaaaga ttggaagcct aatcgtatta
     3001 gagaacagtt agaaaatgtt ctaatggatt tagaaaatga aaaagtaatc tctcattggg
     3061 agtatagtga tccactggat gaacaacaaa ttgggaaacg taattggttt aaaaattatt
     3121 acaccaactt aggaataacg attttaccac ctgaagaaat gctacagtca atggataggg
     3181 taataggaaa gaagagtata gaggaaccac aagagcaatt accggaagta acagttgtta
     3241 aagaaataaa gaagactgta gaatcagtcg aacaaataga gaaaaagatc cgtgaccaaa
     3301 tactgaaagt acacaatgaa aaaaaggtaa gcattcgtga aatagcagat gaaattagta
     3361 tttctccgtc tacattatct aggttttgta attataaaac aaaacgttta tctaaaaaag
     3421 cattagaaaa gctaacgaaa tggtgtgaaa gacaagaaat attagaaaag atgtaacata
     3481 aactaaatat ttattttaat aatagtcaaa ttaaaaatac acatacatta tgtatgtgta
     3541 ttttacttat tactactaat aacagtctga attttcttta ttaatggtgg ttttggaggg
     3601 cgaagatcct actggaaagt caatatagtt atgctgttta atccactgca attaaatttc
     3661 ttgtcttatc gatatggttc agtaacattc gatattcttc ttcatacata gttatacgtt
     3721 gtagaagaga ttgattctct gtttctaaat cttcaatttg attttgtaac tttgtcaatt
     3781 cattcacatc tttataattt tgtagaaaga gaataatatc atctaatgta atagacaaag
     3841 agtttctttc tttttctgat ggggagaggg gaatgttgtt tcccattttt cggtcttgtt
     3901 ttgcttgttg tatttcttct tggtattgtt ttctcacata tgaattccaa cgaaatccac
     3961 aagctgcggg tgttctagct agtagtttcg ctacttcttt gaatgcagct aattgtgttc
     4021 caccgttacg aatattctga agtactgttg atgcgagaag taaatcgtta tcatcagtcc
     4081 aggaatcttg tcttgagatt accacgtttt aacccccctt atatgttcta tattatatat
     4141 atgcaattac tcaaaatgat agaagttcaa cttctcttga aataattggg agtaagttga
     4201 tagaagtatg tatgattgta aatgcaaaat tgcatttaag gttgactatt tcataaaggt
     4261 gtaactataa tagttacagc tatgcaactg aattaataaa atggctggta tgaattggtt
     4321 gtattaatga tgtataaaca aatattaaag aatgaatgga gttgaaaata tagtcctaca
     4381 tataaaacgt ttatataaaa agaaattagg taaaatacat ttttttataa gtatatatta
     4441 ataaaaagag gtgcacgttt tgaaaatttt taagggaatt ctagtttctt caattgcatt
     4501 aacagcattt aatggggtgg gtggactact tccaagtgaa aaatcagaag ttgcctatgc
     4561 agctacctac aattatacaa ataagcaatt gaattctact gtacataagc aagttaataa
     4621 acaattaatt ttgaaattta aaaatgaagc gaatttacca tatcaggatg gaatagaaaa
     4681 atttattaaa gaagaaaaac aagatcctga attaattgaa attttagctg aatatccaaa
     4741 tgtaactata aatcgacttt ttaattcttt aaatcctaaa gaaattaaaa atcttgggaa
     4801 agaaataaaa gattccgatc atatttcttc taatttgcta agctattata ttgtagaaac
     4861 tcaagatgat attgatgtac aagcattact tacaaaaatt gaaaaatcat ctcttgttga
     4921 aacggcgtat ttacaggaag aagaggcgcc accagcagag cgtttgccaa atttatctgt
     4981 taatccatat gatgagccta gacttacaag acaaggttac cttgaaccag caccattagg
     5041 aattaatgca ccttatgcct ggagcataaa aggtggagat ggaaaaggaa ctactttcgt
     5101 agatatggag tatgggtggt tatttagtca tgaggattta gtgaatcaaa agattgaatt
     5161 gatatctgga cagaataaaa gcgagcacca tgatcatggt acctcagtct taggcattgt
     5221 ttcggcagag gataataaca taggtggaat tgggatcgca ccgaaagcta aggtaaaggt
     5281 tgtatcccag attagggata acggaaatta taatacagct gatgctattt taagtgcggt
     5341 taacaatatg caagctggag atattctttt actagaggca caagcaactt acgatggata
     5401 tggagataag aactattttc ctgtggaagt aaaaccagac atatttgatg caattcgtat
     5461 gggaacaaat aagggaatta ttattattga agcaggtgca aacggcggaa atgatttgga
     5521 tcaatttaga gaccgtaatg gtaaacaagt tttaaatcgt aatagtcctg attttaaaga
     5581 ttcaggagca attatggttg gggcagcttc tgcaagggtt cctcataagc gttcatattt
     5641 ctctaattac ggtagtagag tggatgtata tggatggggg aatgcagtag atactacaga
     5701 tgctaaacca agtgaattta taacaaattt atatacatct agttttgctg gaacatctag
     5761 tgcatcacct attattgctg gtgctgcagc atcaattcaa ggaattgtaa aaaataatca
     5821 ggggagagta tatacaccaa gacagcttag ggctatttta agtgattcta gcaccggaac
     5881 gaaatctaat gatccaactt ctgataaaat tggtgtttta cctgacttaa aagccatttt
     5941 atctaaactt ggtttttcac caaacttaag taatgattct tccattgcat ttcctgagga
     6001 acaagaaata aataaaggga ataagggaaa tgaaggatct actattacat tcccaaaaga
     6061 agactccgct aatggtgaag gagactctag ctttattttc ccagaataat tgtaggatat
     6121 cttctattta atataaagga atttcatata actagttgag tataatactg gtgagatagg
     6181 ctcttatgtg taatagcata agagcctatc tgttgtattt ttaaatgaga aattttgttt
     6241 taaagtaaaa ctttattctt tcttaatgta agaatatatt atagatcgta aaagtttaag
     6301 aaaatagcaa aatgattgaa aaaatttcct tttttcttta ggagagtgag aatttaaaat
     6361 aaaatcacca tgatggaaat attacttgca tatatgaagc tattgtaaca gagcctttta
     6421 aagttacttg acgattacat ttgtaaaaat atcctctaat ttgtattata ttatgctagg
     6481 ttttattgca tagtttttaa aagtaagcta gaataattct cagtaaaata tttttaatat
     6541 tcaaataagt tttcggggag cacataatct ttttatcaaa ttattaaaat ttaatttgta
     6601 aattagtaag attatatcgt tttttttgaa ttttcatgtt gaattattag attattaaca
     6661 atataataat tcttgttcga acaaaaaatt acttatttgg gggaaaatag aaatgaataa
     6721 agaattattt gatttagata ttaataagaa aatggaaaca cctactgaaa tgactgcaca
     6781 aactgtgcca acaactattt ttgtatcaag aagtgtttgt aaaacattaa cttgtatttg
     6841 tactatttca tgctctaatt gtaagtaaga agagttatct aattcattag aatttgggag
     6901 cctataaaag agccattctt ttataggctt taatagtttt tatatacata tccgtaaaat
     6961 atttttaata ggtaaacaaa tattaagaga gcatataatc tttttatcaa gttatcaagt
     7021 tatcaagtta tcaagttatc aaaatttaat ttataaagta gtaacattac atttaggatt
     7081 tattttttga atatttcaat caatattatc tctatagaac ttcaaaaaat tcaataaaaa
     7141 tacttttaaa ggaaaaaagt atgaatttta ttattttcat gttggattat tagattatta
     7201 acaatataat aatatttata taacaaaaaa ttacttgttt gggataaaat ggaaatgaat
     7261 aaagaactat ttgatttaga tattaataag aaaatggaag catctactga aatgactgta
     7321 caaacttggg gaacggttgt taaagtatca aaggctattt gtaaaacagg aacttgtatt
     7381 ggcactattt catgcactaa ttgtaagtaa gaagagtgat ctaattcatt agaatttggg
     7441 agcctataaa agagtcattc ttttataggc tttaaaattt aatttataaa gtagtaacat
     7501 tacattcagg gtttattttt tgaatatttc aatcaatatt atctctatag aacttcaaaa
     7561 aaattcaata aaaaaccttt taaaggaaaa aaagtataaa tttaattatt tttacgttga
     7621 attattagat tattgataat ataatgattt tgtttaggtg aaaaaatact tatttaggag
     7681 aaaatagaaa tggataaaga actatttgat ttagatatta ataagaaaat ggaaacacct
     7741 actgaaatga cagcacaaac ttggactagt attttaaagg tgtcaagggc tccttgtaaa
     7801 tcaggaactt gtctttgtac tacttcatgc tctaattgta aataagactg gtaatctaat
     7861 taattagggt ttgggagcct ataaagtagc cattctttta taggctttaa aagtttttat
     7921 ttacatatcg gtagcttatt tttaatagct aaataaacat taaggaagca tataatcttt
     7981 ttattgagtt attaaaattt aatttataaa atagtaacat tacatttagg gtttgttatt
     8041 tggatatttc aataaacatc atattcctcc caaggaaact tcaaaaaaat tcaataaaaa
     8101 aaccttttaa aggaaaaaaa gtataaattt tattattttt atgttgaatt attagattat
     8161 tggtaatata ataattcttg ttcgaacaaa aaattactta tttgggggaa attagaaatg
     8221 aataaagaac tatttgattt agatattaat aagaaaatgg aaacacctac tgaaatgaca
     8281 gcacaaactt ggacaactat tgttaaagtc tcaaaggctg tttgtaaaac aggaacttgt
     8341 atttgtacta cttcatgctc taattgtaag taagactagg gatctaatta attagaattt
     8401 gagagcctat aaaagagcca ttcttttata ggctttaaag tttatatata tccgtagaat
     8461 atttttaata ggtaaaccaa tattaagaga gcatataatt tttttatcaa gttattaaaa
     8521 ttcaatttat aaagtagtaa cattacatcc aacaattatt tttttgaata tttcaatcat
     8581 tattatctct atggaacttc aaaaaaattc aataaaaatc cttttaaagg aaaaaagtat
     8641 aaattttatt atttttatgt tgaattatta gattattggt aatataataa ttcttgttcg
     8701 aacaaaaaaa ttacttattt gggggaaatt agaaatgaat aaagaactat ttgatttaga
     8761 tattaataag aaaatggaaa cacctactga aatgacagca caaacttgga caactattgt
     8821 taaagtctca aaggctgttt gtaaaacagg aacttgtatt tgtactactt catgctctaa
     8881 ttgtaagtaa gactagggat ctaattaatt agaatttgag agcctataaa agagccattc
     8941 ttttataggc tttaaaagtt tttatataca tataagagta tttacatgga tttataggta
     9001 ggtgttaatg tagatggata caatcaggga aaagttaagt agttacaaac caaacattta
     9061 ctgttggaat acaagtagat taagtgagca attcaaaaca tatgatatcg aaattggtca
     9121 tccaagtata aaaattgcta ttttggatag tggctgtgat tatcttcatt cagaattaaa
     9181 tgataatatc cttattaata aatctaaatc aatgatccct tatgaagaga atattgaaga
     9241 ttacaatggc catgggacag cagtaattag ttctattata ggtaagaaaa atgttaaggg
     9301 aattgctcct gcagtaagca tccttagtta taaaattgta gataagaatg gatatggaga
     9361 attaagatgg actattaatg ctattaaact agctattcaa gaaaatgttc acatcataaa
     9421 tatcagttat acatctaata aaatagatga tatcgatatg atttatgaat ataaagaagt
     9481 tgttaaggag gcaattaata aggggattta tgtaatatgc gctgctggaa atgaatgcaa
     9541 agaaatcaag cagggttcag aaaacctccc gatatattta gcggagggga tagttatagc
     9601 atctacagac tataaaggag aactgtcctc ttttagtaat tatggagtag ggatagattt
     9661 ctccatgcca tcaggtggat tttcacaagg tttcccttct cagtatggat tggtgattgt
     9721 ggcaaagccg cgttcaatgg cacggttaca tttggaagat caatatcaag ttccgaaaga
     9781 ctatactctt actatgggta caagcatatc gtctgcgttg tttagtggaa ccatcgcttt
     9841 gttattaagt agatactata gattatataa aaagttacca aagagaaatg aaattttaag
     9901 tttagttaag ttaagtggta aacaaataaa caggcattat tcaatggttg aagtgaatac
     9961 gtatagagct ctaaatgaga ttaagtaagg aggaattaat gtgaagcatc aattactaaa
    10021 tacatatatg taccgtaaac ccattttaac tttaaaagag tatcaagagc tttttgattc
    10081 aaaaatatca actttagaat acgaaaataa gataaaagag atattttcag atgataaatt
    10141 aaaattagct atatatatat caagtcctac tatgtatgaa gctttaaata ggttagacag
    10201 tttagatgct aaaaaaaaga gaaacttttt acatggtatt accaaatttc taataagaat
    10261 gtctacaagg ccaactcctt tcggtctctt cgctggtatg ggaattgaat ctatcaataa
    10321 taatggaaaa ggatcattca atatagattc gtattttagg ttagattttt ccacaatata
    10381 taaaatcgtc gaagtgctag aaaatcagga tgagattttg aaaaaagcaa atattagatt
    10441 taataatctt ctttacaaac atggtaatag gttgaaatta ccatatcaaa gtaatgtaca
    10501 taataaggac aatatagatg agcatatgaa aattatgact gttaaaaata gtccagtttt
    10561 agattatata cgtaaaatta caaggaatga tatcaatttt gaacaacttg tagataaaat
    10621 taataaagag tttaatactg aagatactac atctaaaggt tatttgaaaa aattaataga
    10681 taatgatatt ttgttttctg atttaagacc agcattatct tctaatgatc cctttaagta
    10741 tctcattact atcttagaag aaaagaatat taatcatgaa ttgttagata atttaaaaca
    10801 aattaatttt tcattagata agtttaattt aactaaagaa gaaatttctg ttaaggaatt
    10861 aagtaatttt aaatcacttt taaaaacctt taaattatgt ggagaaaaag acataagagt
    10921 agatgctaag ttaactaata gctcggagtt agctttagga gatgaagata taactaactt
    10981 agaggaatta agtagaataa tgagctatct aggatgtata aatccacttc aagttcttaa
    11041 ttcgtatagg gattctttta ttgagaaata tggcccttat caagaagtac cgatattgga
    11101 acttttagac gaagatttag gtttaggaaa gcctaatgat tacgtaacga atggaaactc
    11161 tcaaccacaa ataagtgaaa accttagagc agttaggaac ttaattcaaa aatggcagac
    11221 cgaagctctt attaataatg aaaatattat tcttgatgaa gacaaaatta aagaaattaa
    11281 aaaacatatc agtagaaatg atattgaaaa agaaaatatt gatttagaac tctattttaa
    11341 ctattttcaa tgcaaaggtg caaacaaatt ttatttagtt cctaatacag gttctactca
    11401 aataggtaac acctatggaa gatttaaata tatgtttaac aaaaatgaaa taaatcaatt
    11461 aaaagatttt aatgaattca tagaagatca agatagtaat ataaaatttg cagacttaag
    11521 gataaatcca gacaatagca gtttagctaa cattatgaat tcacctagtg tatataagag
    11581 tgaaataaat ctttgtacta atcctagtga aagttgctct aataatattg atatagaaaa
    11641 tttagttgtt ggtattaata acaataaatt ttacataaga gattcctctt ctaataatat
    11701 tattatacct aaaataagta atatgtttaa ttatgaaaat gcaaatctta tatatcgatt
    11761 tttagctgat gttggtgctc tatacagtgg aatatgggga aatatacatc atcattttta
    11821 tgatagtcac gtatatccta agatagtcta taaaaatatt gttgtttctc caaagcgatg
    11881 gattttccat catacattta ctcaaaagat gtctgaagaa gaattcatct cagttttctt
    11941 agattggtgt actagaaata acatcacaaa ttatatttac ctcgccgagt atgataataa
    12001 attattgcta aatataaaaa atgaattaca tttaagtata atttttcaag aattctcaaa
    12061 gttaaagatg aatgatagat taagcctttt tgaatgtgaa gaagatatat ttgtttcttc
    12121 aaataaacgc tttgaagaat gtgtctttag ttttaggcaa accgatcgaa aaaaaattac
    12181 atttactaat tctttaaata gaaattatca atacattaat gatatgaacc gtgtaaagtt
    12241 attaggaagc gattggattt ctttgcgtgt aaactatgtg gattccagag ttgaagagtt
    12301 tttatcttgt ggatataaag aattttataa acacaataaa gatatcaaca agattgaaaa
    12361 aggatttttc gttcgctatg cagatcctac tccgcaccta agaatacgtt ttaagctttc
    12421 gaaaaatgaa aagtataata catttttagg taatattact gaatggttaa caaatgagag
    12481 agaaaagggg ttagtcaatg actttcattt tgtatcatat aaccctgaaa tagaaagata
    12541 cgggaatttt ttaattgata aagctgaaga tatttttagt atagactcat taattgtagc
    12601 agatagcttt gaaggagatg taccattaaa cagggaactg ttttgttgct taaacattat
    12661 gagtatccta aaaggattta atttaaattt tgcaagtcaa ttggaaattt taaatatggc
    12721 tatagaccct aaaatgtata aagaagccta tcgagaaaat aaagcaaacc tagatcctat
    12781 tattacaaac atatatgatt atattgagat tccgatgagt gaaaagctta ttattcctac
    12841 tacatttaat gatagagaca atgttataag aaaatatgcg gaacttatag atgcaaatga
    12901 agatgttctt actaatgtga aatctgatat tattgcgagt atccttcaca tgcattgtaa
    12961 ccgcttaaat ggaataaaca gagatttaga gaataaaatt ttaggtatgt gttatcatac
    13021 cataaaaaaa tatatgaatc tgattaaata taaatacaat gtattagtat gaggggttat
    13081 caaatgacta ttaaactaaa tgaaaatgaa ttaaagacat taaatgagat taatcaaaag
    13141 ttaattaaat tgtatagtga ctttgagaag gttgaaagct atattaacga ttctgcttct
    13201 cctgggcttg aggctataga actagcttct cttgctggag gatatgctgg aatagcttta
    13261 gccttaggag tttctgatga tgtatcatcc aatcaaagta cggatgaaat ttcatatgag
    13321 tatataaaga gatgcatagc aattattcaa agcaacccta catactcatt ttctttattt
    13381 tctgggttaa caggaatttt aatttcatta aagtttaact caaaaaatgg acaaagatat
    13441 aaaaatataa ttgaacaact tctacaagta attacacata attataagga atcattaagt
    13501 ataagccagg ctaatcttat taacaataca gtaactactg atgatttcga tgttatatta
    13561 gggtggtcag gtatattaag gacccttctg gaatttgata atgatctata tgatacagaa
    13621 ttaaataaga ttattgaaga tatatcgcta tatctcatca aattaggggc atttacaaat
    13681 gattctaaac cgtgttggtt tattgaatat gcacaattaa gtgatattga aaaagaaact
    13741 tttgtagggg ggttctacaa taatgggatg tcacatggca tatcaggagt attagcaagc
    13801 ctttctatct tatatataaa aggttataga tttaatgggt tagagagcag tattaataat
    13861 atcagaacgt ggttgttaca aaatatttta gaacatagag gcgtagaata tattcctaat
    13921 gttacggtag ataatactaa tacgtttaat caccgagatg cttggtgtta cggaactcct
    13981 ggtgtatcca ctgctctttt tatttctgct atgacagatg agaatctgta tattaaagaa
    14041 aaatccatag aactttttaa aaccttttta aagagagcta gtgaggaaca caaacttata
    14101 tcccctacta tctgtcacgg ttttgcgggt attctaatgt tatgcataag attgatagaa
    14161 tatggtgtaa gtgacccaga gatattagaa atagcaaata atgtttttca aaaattaatg
    14221 agtttctaca aagaaaatga attgatatta tttcctgatt atgaaataat tgaaaataaa
    14281 cgagttgaaa ttcataaaat tggattatta gagggggtaa cgggtatatt tcttatcatt
    14341 caatctttgc ttcatgacaa gaatgaatgg gatcaaatat ttctaatctc gtaacgttta
    14401 acaaattaaa gcaacaggag ggattcgtga tgattgaaat tttaaggaca ctagttaatt
    14461 ttttaattgc tctattttca ggagaattac ctgggatata ttatatttgg attattgctc
    14521 tattaatagt tcaaataatc cagtctacgc taaattataa tctcttcaat aaaaaagaaa
    14581 aattttctaa gtatacaatg gaagggttat tggcttttct aattatattg attggaagca
    14641 tgttattatc taagttactt gctttcataa tagaagactc agttattaat aagacagagt
    14701 taacacatta ttttgtctct cttatagtat taactatatt tgtggctata ggctgtatta
    14761 aagagttaat acggcatacc ataaaaaata gtaatatgtc tcttgtaaca tttataatcg
    14821 tttccttaat agctagtata ctttcattta aattattatt acctttaaca ggcggttctt
    14881 ttacgctctc taagtctttt attaatactt taattattgt agttactggg ataattgttc
    14941 tactagttag tatggaggag aaatatgtag atgaagaata attcattaat taagacctta
    15001 aagattgtca attggccaat cgcaaaggtt ataattgcaa tttttatatc tattgtctct
    15061 gtttttgtga gtctacttgt tcctatatat ataaaagaaa taatagataa aattgatttt
    15121 acaaatctcc ctattaaaat aattttatta gtcatctcgt tttttattat cgcatctttt
    15181 ttacaagggt tatcacagta cctcctgagc tatattggag agcttactat aagggattta
    15241 cgtaaaaaca tgtgggaata tataattaat ttgcctgtta aatattatga taataaggaa
    15301 acaggccaaa taatgagtag attaattgag gatagttcta tagttaataa ttttgtttct
    15361 atgaaactgc ctattatgtt atcgcaatta attttatttt ttggagcttt gggcctaatg
    15421 atttacatgg attggaaaat aacacttttt atgttaataa cagtagttgt cactactgtt
    15481 attattattc cattaggcaa taagatttat gttatatcta ctaaccatca acaaactatt
    15541 gccgaattta gtggcatctt aagtagagta ttatcagata taagactggt taagatagcg
    15601 aatgcagaaa atttagaaat taaacgtgga aatgataaat tagaaagact ttttggatta
    15661 ggcataaaac aatcaaaatt gtattccttt attaaccctt taattacttt aattataatg
    15721 ttcactatta ttggtatact aagttacagt ggttatagat tatctgttgg tactctttct
    15781 acaggaacat tagtagcttt attgttttat ctattacaaa taatagaacc tttaactggt
    15841 ttgagtagtt tttttacaga ttataaaaag actttagggg ctactgacag gatacaagaa
    15901 atttataaaa atcaattaga gaataaagct ggttatgctc catcgtatga gcaagatata
    15961 agttttcaaa atgtatcatt ttcttatggt gagaaggaaa tattaaaaaa cgtaaatttt
    16021 ttagctgaaa gaaataaggt aactgcattt gtaggccctt caggagctgg aaaaagtaca
    16081 attttctctc tattagtgaa attgtatgag tgccaagatg gaaatataaa atatggcgat
    16141 cagtctatta ataatatcga tttaacttta tggagaagta aaataggata cgcaatgcaa
    16201 aatgctccag ttatgaatgg aactgttctc gataacatta cttatggact aacaagatct
    16261 tattctatgg aagaaattca cacagtcgcc caaattgcaa acgcacatga atttattatg
    16321 aatttggaaa atcagtttga tactttagtt ggagaaagag gaattctatt atctggggga
    16381 caaaaacaga gattagcttt atgtagagta tttttacata atccagaaat cctattgctt
    16441 gatgaggcta cgtctagttt agatagtgaa agtgaaaaac atattgagag agctataaat
    16501 tatgtgaaat ctaataaaac aacactcatc attgcgcatc gtttatctac catcatggct
    16561 gctgatcata ttattttcct tgatgatggc aaaataacag gtcaaggtac tcatgaggaa
    16621 ctattgaata ctcatgaacg ttatagggat tttgtgactt atcaaacaat taaatagtat
    16681 attgatagaa tttgccggct tccatacttt gagaatggaa gctcttttaa tgaataaatt
    16741 attacttgtt ttttgtatga gaagtaaatt ttaatgttag catcatttta attgtaaaag
    16801 aacaagaata tggtatatat ttattagatt tcattattat ttctaatttt aataagcttt
    16861 tctatatatg tcagctatct aaaaacctag atgtaataaa attaataagt actttcaatt
    16921 ttttttgaaa taaaaaggtt gtcaaagctc tttaatataa attaaagttg ttccatattt
    16981 ttgttatgat gcaatcaatc cttagcgtgg gttatatgtc agtgcgtttg tggtacccct
    17041 tataaaaaat tgagagtact taggggtctt ataaataaaa agtaagaatt ttcactttag
    17101 ccccgtcttg taatttatct attttttata tgcagaaaaa caaagataat ctgaagagca
    17161 tcaaaaggaa agaagtgcgt taatatttag ttttaagaag atttcgctct ttattatcat
    17221 ttttttgtta tccggaaggt ttgggaatga ttatgatata ataaaattca agtacaataa
    17281 gggggattaa ttaaatgatt tttcaaagca tgataacagc tattatagaa aaattacaag
    17341 agacggtgaa tccctattgg ataattgtgt ttggatcaac ggctgagaac agagaacgag
    17401 aagatagtga tattgatata gcttatgtaa gtgacacaac attagggaac tatgaacgtt
    17461 ttttattagc acaggagtta gctaacattg ttcatagaga tgttgattta gttgatttat
    17521 ccgaagcttc tacagttttt caagctcaga ttatacatac aggaaaaaca atattttgtt
    17581 cggatgaaaa acgtaaggtt atttttgaaa tgaaaacctt aaaaatgtat tcaaaattga
    17641 atgaagaacg acaggtagta tttgaagata taaagaaaag aggttctata tatgaagaat
    17701 gaggttattt taaataaaat ttctacaata gagcgttgta taaaaagaat ccaagatgtg
    17761 tatggaaatg cccctgaaaa tttagaggac tttacaaaac aagattcaat aatattgaat
    17821 atacaaagag cttgtgaagc gagtattgat ttagcaatgc atattgttgc gggaaaaaaa
    17881 ttaggactac cccaatctag tcgagaggcc tttgatttat tggttacagc aggattactt
    17941 agcgctgatc tagcaaataa gttaaaggcg atggttggat ttcgtaatat tgccgttcat
    18001 gattatcaaa gtgtaaattt agatattgtt cgtcaaatta ttgaaaaaca tttaactgat
    18061 tttaaactat ttacaaaaga agtaatgggg atattggaat tttaggaaaa agaacagaat
    18121 aatagggctg agaaagaaag taattctatg attcctaaag cagctattga aacaatcact
    18181 taatttcgta agaagaaatg cggtcataag aagaatttgt ttatgttgta gtgaggcttt
    18241 gcatgagatg tgtagataat atagtaggga aaatatccat atacaatttt atcaacaaat
    18301 aagtaactat tttcaaaact aatttttatg catataatgt atacccaaaa caaaagagtt
    18361 tccttatgga aacttttttg ttttgggtaa atttataatg gttaattaat attcagtttt
    18421 tgaaaaaaat gatgaatcat gtcaaatcat cttcatttac acaaacatga acgtagtata
    18481 aaaatgaagc atatccaaaa taattaaagg ggctgaaaaa aatgattaaa aaacttatta
    18541 ttagttctat tgctttaggt gcaacaatag gagtgagcaa acctacattt gctgctacaa
    18601 tacattctcc atcacagttt aaagaaactc gaaatgttca tgtgcaatcc ctatattctc
    18661 catggcagta tttagggcaa acttcaaggg aacttcaaat taaaagtaag gatccaaaag
    18721 tactagcttt tgaactagca aggaatgggt tagatttgaa gaaggaaatt atgaatttaa
    18781 acatgaaatt aaaattttta gagataaaga acgtcagcaa ttaattacga cactagaatc
    18841 ttagttcttt tacaaaaaaa gaagctatct ttagtatgct attctcccct catagtagat
    18901 aggaaaaaga aaacacatta acctatttat tatggagggg atttttctat ggggtaaatt
    18961 agaattactt gctatacaaa atgaaaggaa aagaaaatga gtttatactt aaaagaagat
    19021 ataaaactgt taagaaagaa atagacattt attattcaat tgtaagacgt tggatgaaat
    19081 aattcgaaac tttaggtatt aaagaactag aagaagaacg tggggaaaca aaagggttat
    19141 gtttaggtag aatgaaacct aaaggttcgg gtactaagac taaacgattg gaagaagagg
    19201 atgggatgtt agaaaaatga aggaaagtat gtcgcgaaag taaaactttt aggataatgc
    19261 atataacaaa gacttcttca tctatgttaa ggccgcaaat atatacaatt ttataaccat
    19321 caaacatttc aaaagaaatt aaataacctg agtccataca aatatagact caggtggttt
    19381 agctatactt taaaaatact gtctacctga cagggccctc tctctgtatt attcaaataa
    19441 acaaactgaa acaagactat tagaattatt agcgaattat cctctcttta attcttatat
    19501 cgtgtctctt acttctaaca agtacaaaca taactcatta atctatatta tctttaaaat
    19561 atttataaat ttgatgctat aaaagcaata gaattatgta ataagtgaat caaaaaaaca
    19621 acccaaaaag cagacatggt aacctgatat ttttcattct tttttttata tacccaataa
    19681 gcatagttat ataaaagtcc gattatcgtt gtaccaacta tataagtgat tccatatgga
    19741 tgatttaatc caaatataat tgaagctatt aaaatgataa ggtaatcgcg atttttaatg
    19801 taaggaatcc aacttaatag ccaaaataaa aatacttgaa aaattactgt ttcatatata
    19861 ggtgccgcta atacccctaa taaaacttga agaataaggg gtgcttctgt tattgggttt
    19921 ttttgtattt caggtaagaa tagatctaat ggtattacga ataaaaatga tcctaataaa
    19981 ataagaaaaa caaaagaaat ggtaggcaaa gcaaacataa atctatttat ttttttgagc
    20041 atatatattt ctcctataat cttttattac atctataaaa aaagtaataa ataattgagt
    20101 ctctttttgt tcgacatgtt ttcgtctact attgatgaaa atccttctat aattgcatcc
    20161 ttggcttata tgtaggtgta gcgataaagt agggatatat taaagagcta attgagatat
    20221 taaagtcaca ccagttttta tgatgaataa tatatcaagc ctcttaagga aatctgctgt
    20281 ataggacaag catgtattga ttattttact atatgaatat ttaagtgcat atagttctgg
    20341 agaagtatgt atttttgcat tttttaatac aaaaactttt tattaaaact taacttacta
    20401 cgctacctca tatgaagtta agataattga agaattaagg ttaaaagagt ctaagtttaa
    20461 tttgtacagg tagatattaa aattttatag aaaaataagg aaaaaagtta taaaatagga
    20521 gattggatta aactttccaa ttttattgtt gtgcaagata aagatgaggc tcttaaaaat
    20581 tcttgttttt atataaaact aacgatagtt taaaaaatcc tcactgaagg aactccgaca
    20641 aatctaatgt gaaaatttct aggcgataaa tgtgaaattt aaaatattct tagtagtcca
    20701 ttaaatatta taggcaaagc ttttaacatc atcgatttag aagaaatcag tacaaataga
    20761 aaagatgaag tagtagaagt attacgtctt ccttttaata gatttccaga agcagctgga
    20821 tatataaaag atgtgattgc aaatggaaaa actgatattt gtacaataga tgaaaatggg
    20881 cttcaaaaag aagaaaataa actttagcat ttttaatcat aggtatcata actagtaatt
    20941 ctttagtggt gctatataag atagtgttgt aaattagctg cattttaatg ctcattacaa
    21001 tggcatcatg cttttggatt gaaatacata aatgcttaga ttcgttaaat tattacttta
    21061 aatatagtga aactatcagt atataaggaa ataaatccta tcaagtgaaa aaattggaac
    21121 gtttggttga atgattagta tactatttta aaattcaaat taataacaga aagagaacct
    21181 cttaatatgt tactactttg tttttttatt gttgaaaata agaaaggtga aatcaatgaa
    21241 aaaatattgg cataagctat cgctgcttca aaaaaatgta ttactaacgg tattattgat
    21301 tttgacgctt gttggaagta tgggagcgtt aagttttaat atgtttcaaa atagtatgat
    21361 gtctatattt gagaggcagt cttttgaaac aggtgatgca gtattaaatc aattagatct
    21421 agaaatagta agagatgtag caaaagaccc cacagctcaa agagtgaata aagaaaaatt
    21481 gacagagcaa ttagataaag ctataaaaga tatgaaaagt gttgggcaaa catatgttac
    21541 tggagccaag ctaaatgata aagctgaatt acaaatagta gctttggata cagaattagc
    21601 aaatactgtt tctgtaaaac caggtgaata ctatgagcag cctacttatt ggatgaaaac
    21661 atatgataaa gtaaaacaaa caaaacaggc acaaatgaca gaagtgtatg aagatgaatt
    21721 agggttctgg gtaacaattt tagagccagt tacagatgaa aataaaaata taattgcaat
    21781 tgttgcagcg gatttggaag cttctattat tcctcttaca aagaaaaact ttatgataca
    21841 aggtttacta tttattataa tttcattaac tatcgcaatt acaattcaaa tatttatctc
    21901 acgaaactct ctatcgcctt taaaggattt acaagaaggg ttacgtaaag ttggtgaagg
    21961 ggatttaagt ataaaattga atgaaagacc tgatgatata gggataacta atatctattt
    22021 taataacact attaaaaagt ttaataggat tatagataaa gtaaggcaga ctgctgaaca
    22081 ggtttcgaca tcttcacagg aattgtcggt aagtacaaaa gagaatagca tagcctttaa
    22141 agaaattgca agtgctatta caggattaaa tttaggagca cattctcatg aatatgtagt
    22201 gcaaaaattt ttaggaattg tacaggaaat ggaaagtaag atgaaagaaa ttaaaggagc
    22261 tgcaaaacaa gttgggaatg tttcggaaga catagaacag cattctgtag agggaaaaga
    22321 tttgattaag caaattgtga atcaaatgaa aagaatcaaa gatacagttc aggatgtatc
    22381 ttctagtatt tatgcattag aagcacgatc taaggaaatt aatgaaattc ttactgtaat
    22441 tacaaccatt tcaaaccaaa caaattcatt agctttagat gcttctactg aatcctcatg
    22501 tgctggagag atgggggaag aatttccagg tgttacggac gaggtacgta tattagcgga
    22561 aagaaccgag gcacctgcaa gggatatagc taaattaatt ggtgaaaccc agactgaagc
    22621 agagagagct gtaagatcca tacagaagag ttcaaaggaa gtagaattag gaataatact
    22681 tgttcaaagt agtggtgctt tttttgaaaa gatttcagaa tctgcacaat ctgttacaaa
    22741 tcaaattaaa gcgacttcga atcattcaag tgacattcta aaagataatc aaactattgt
    22801 tcagtttgta aatgaattat cacacattgc aaatacatat gtgaatagca gtagtaatgt
    22861 ggagaaaagt atgaaagagc aagaactata tgtacaagat attgcagagt tagcaaattc
    22921 tttaaattgg ctctcgcaag agttacaggg gttaataggg gaattcaaaa ataagtagga
    22981 taggggaagg tgtaggtata gagtatgacc tataccttta tttattccta tataagagat
    23041 gaaagcttag gtatatatgt aaaatagcta aacgaataac tttttgcata ttttgttgga
    23101 aatagagcat gatattacca aattcaacgg aggtgtttaa aaaatgcaaa ttcgcgaaaa
    23161 taataattca aacgaaatct taatagcagc tgcagcaagt gcaattgaac aaatgaaata
    23221 tgaaatcgct caggagtttg gtgttacact tggacctgat tcaactgcac gagcaaatgg
    23281 ttcagtaggt ggagagatta caaaacgttt agttcgtatg gcgcaagagc agctatctgg
    23341 tcaatataaa attcactaaa actaaaggta tatcccattg aagggatata cctttttaat
    23401 ttgtttttaa agaggatcgt tacatttttt attattggtt aagtttagaa acagcaaatt
    23461 tagctgtaaa attcatcttc ttcatgtacg tagaatttac acctgcttga aattgtacag
    23521 aaatattacc gtctttttgt gctttaaata cgcgaccata tggggaatta gcattgaatg
    23581 taccaattac ttgattatca gcatcaaaga ccgtataaga aattgggaac cctgaatttt
    23641 gcacaaagac tgtaagttct tccccttttt taagattaaa tgattctttt tgagacactt
    23701 cataggaact catagagtag tattttgtga cttcttgaat ttctaaattc gtagtagctg
    23761 cactcgcttt tgatgcctca gcccctggta agttcatacc tgataatact gcaattccta
    23821 gtgcccctgc taaaatcaat tttttcatac tagtatttcc tcctttaata tattgtgaga
    23881 tttgaaacga aagtgaaaat ctcaatccct gaaaccatta tagttacaat gagaactatt
    23941 ttcaatggga attggtatgt aattttgcat acacaaagta gcgatataag gtaatctatt
    24001 caagttttga agtcttctta acagaaggga agggtaattt aaaaaaatca tgaatgagat
    24061 tgtaaatgaa ctttatatct tatgtagaaa gactagaaag tggggaattc ataatttgaa
    24121 aacaccaagg tggagttttt ctgaatggaa atgaacaatc ctctattaaa aatatttttt
    24181 aacaccaaat atattaaatt aatcctcata taacacatta tttttcagta aatgttaaaa
    24241 actttacgcg tatgtaaatt tttaacatta ctatttttct caattgtata attttatttt
    24301 cgaattatac ttaattcgta ataccaaaat taggaaagga cctttgagac aggacattta
    24361 tcttaaattc ttatttagag gagtgattta aaaa
//
