LOCUS       NZ_CP015612            20879 bp    DNA     circular CON 05-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain OUC_Est10 chromosome, complete
            genome.
ACCESSION   NZ_CP015612
VERSION     NZ_CP015612.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4668743)
  AUTHORS   Dong,H., Rui,J., Xue,C., Li,X. and Mao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAY-2016) College of Food Science and Engineering,
            Ocean University of China, No. 5 Yushan Road, Shinan District,
            Qingdao, Shandong 266003, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP3 in SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 123x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002138415.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 21:48:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,285
            CDSs (total)                      :: 4,195
            Genes (coding)                    :: 4,163
            CDSs (with protein)               :: 4,163
            Genes (RNA)                       :: 90
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 32
            CDSs (without protein)            :: 32
            Pseudo Genes (ambiguous residues) :: 0 of 32
            Pseudo Genes (frameshifted)       :: 12 of 32
            Pseudo Genes (incomplete)         :: 20 of 32
            Pseudo Genes (internal stop)      :: 6 of 32
            Pseudo Genes (multiple problems)  :: 4 of 32
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:11:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3273294
            Orig. end                         :: 3294173
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP015612.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Strain available from Biochemical Engineering Laboratory, College
            of Food Science and Engineering, Ocean University of China.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20879
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="6"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20879
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20879
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10879](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10879
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(433..1677)
                     /locus_tag="A7326_RS15195"
                     /old_locus_tag="A7326_15050"
     CDS             complement(433..1677)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410514.1"
                     /locus_tag="A7326_RS15195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15050"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_088028431.1"
                     /transl_table=11
                     /translation="MADLPDGRPVNAASPSLQPVASGERIAVLDVLRGAALLGILLMNI
                     EAFSGPLDLAFTGIDVHWQGIDYWADAFVYVFVQGKFFTLFSLLFGAGFAVMAQRAEVA
                     GRDFTPFYLRRSAGLLLIGLCHALLVWSGDILVMYALISLPLLACREAPRSWLPWMGVI
                     VYLGGVAMMLLVGAMVSMASVEDVQKMLTDAQQSIELQRQVYGQGSWMQANVQRLSEFS
                     TSMGALLITGPEVLGMFLIGSWFAGSGALAAPERFPRLYASLRWIALPLGLLVTLIGVA
                     WKPYLAPGAYDLPVTAAMALVTIGGLPMCLGYLAWIVHWRARLAWLAPVGRMALTHYLG
                     QSLLCTWLFYHYGLGGFGLMPRSVQLLFALLLFAVQVALSHVWLRRFRFGPMEWLWRAM
                     TYRQWPPMRRGAGQG"
     gene            complement(1777..2259)
                     /locus_tag="A7326_RS15200"
                     /old_locus_tag="A7326_15055"
     CDS             complement(1777..2259)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418041.1"
                     /locus_tag="A7326_RS15200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15055"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_088026695.1"
                     /transl_table=11
                     /translation="MKIEKDRVVRFHYTVSEVGQEPIESSKDRGEPLAILIGHGNIIPG
                     LENAMMDKEAGATFNVDVKAADAYGERREGLSQRVPKKHFGNTKLAPGQQVVLQTNFGP
                     RAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVDVREAGQEEIDHGHVHGDGGHHH"
     gene            2333..2911
                     /locus_tag="A7326_RS15205"
                     /old_locus_tag="A7326_15060"
     CDS             2333..2911
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005414114.1"
                     /locus_tag="A7326_RS15205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15060"
                     /product="C40 family peptidase"
                     /protein_id="WP_198360807.1"
                     /transl_table=11
                     /translation="MTANPKVAHYPEIMHITPVSSGLRRLLAPALLLALPVLMTACGGG
                     KVTRPAPPPPTANWPKTVPDNPEAANSVLMRAISLVGTPYRYGGNTPDSGFDCSGLVAY
                     VYREMLDLKLPRTSRDLAAVQGPKIDPQRLATGDLVFFGSRGSVTHVGIYVGEGRFVHA
                     PSTGGTVRLDSLSGPYWKDHYTGAKRVLR"
     misc_feature    complement(2937..2952)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    3020..3029
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     misc_feature    complement(3032..3047)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            3109..3816
                     /locus_tag="A7326_RS15210"
                     /old_locus_tag="A7326_15065"
     CDS             3109..3816
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003475603.1"
                     /locus_tag="A7326_RS15210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15065"
                     /product="C40 family peptidase"
                     /protein_id="WP_232460666.1"
                     /transl_table=11
                     /translation="MLGLALCLTSLPAWSQTAPNRSDVTPAPVAESTARPATKAEAAAP
                     QRSRVDAAASATLAALLPHLAANDTIPLMDRSAVVAGDLSRLLANYDTSSAANGSVVGT
                     AADNGKVQSLLRRAMTLLGTPYRWGGSNPDSGFDCSGLVGYVFRSALGIELPRVSREMA
                     HDDKAELINDRTALAAGDLVFFGRKGRVDHVGIYVGDGRFLHAPSSGKDVRVDTLLSGY
                     WGNKFMQARRVDL"
     gene            complement(4144..5478)
                     /locus_tag="A7326_RS15215"
                     /old_locus_tag="A7326_15070"
     CDS             complement(4144..5478)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014038012.1"
                     /locus_tag="A7326_RS15215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15070"
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="WP_005410518.1"
                     /transl_table=11
                     /translation="MKLVSAWLRIPFWQRVVGGFVLGALAGWALGPAAETWFGPLGELY
                     VTLIKMIAVPLVFFAVINAISSLHGQKSVAALSGRTFLWFVITAALAVCVGLGVGTVLQ
                     PGAGGLQLTMASNYVPREVPSVVQVLLDVVPANVFYALSGIGTKVNAAGETVLAAGRGS
                     ILPVIFFAGLVGFAIVKLGEKVTEARKLVGQMSDIMIQVTRFVLEVTPIGTFGLIAGLV
                     GSYGFEKLLPLGHFVLALYVACALHIVVVYSALLLAHGLNPLKFFRGAAPGMQVAFVSS
                     SSFAAMPVALRSITHNLGVNKDYGSFAVPLGASIKMDGCGAIYPALCAVFIAQYSGVPL
                     TPEQYVVVLIASVLGSFGTAGVPGTAVIMATVVLSAANLPLETIGYLYAIDRILDMMRT
                     MTNVTGQMLVPVIVAKETGLLDQAVYDNPSSNVGVDDPDPTPPRG"
     gene            5633..7339
                     /locus_tag="A7326_RS15220"
                     /old_locus_tag="A7326_15075"
     CDS             5633..7339
                     /EC_number="3.1.3.1"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660635.1"
                     /locus_tag="A7326_RS15220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15075"
                     /product="alkaline phosphatase"
                     /protein_id="WP_088026697.1"
                     /transl_table=11
                     /translation="MRRSVSLLAACATTLLLGACASTAPASAPAGLKVAVDPVVHPAGE
                     TPQWWYRSGAAQAAANGAMSGKAKNVILFLGDGMSLTTVAASRIYEGQQKGGSGEENLL
                     SWERFPATAFSKTYNTDSQTPDSAGTMTAITTGVKTHMGAIGVSAGSRTDCADSLSKGL
                     LTWLQLADSAGLATGVVSTARLTHATPAATYAHSPERNWENDTDLTEAAKAAGCKDIAQ
                     QLLSTSRYGRGPLVALGGGRGEFTTVEERDPEYDDKVGQRLDGRSLVQEWQQAHPQGAY
                     VWNSKQLAAAANAPAILGLFEPDHMRYEYERPQDPGGEPSLAELTAAAIKNLAKHQEGY
                     VLMIEGARIDHANHSGNAYRALTETVALSDAVRVANELTSADDTLIIVTADHSHTLNFV
                     GYPARGNPILGKVKDKGGEDGAGKLDYALDGSGQPYTTLSYANGPGHTGSSNQQPAGPK
                     RYPHNPSSFEPANGRPNLREIDTEHPDYMQEALVPMKSESHGGEDVGIWARGPGSKAIR
                     GTLEQNAIYHMIVQATPALRERLCQAGTCDDKGVPVQLPAPTAFERKAEAK"
     gene            7336..7881
                     /locus_tag="A7326_RS15225"
                     /old_locus_tag="A7326_15080"
     CDS             7336..7881
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660636.1"
                     /locus_tag="A7326_RS15225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15080"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_088026698.1"
                     /transl_table=11
                     /translation="MITRQARPAPASGRFARSLVLLGVLVSANAAAQAPACKLLTDEHG
                     LWPLPNCEVVDHRPKISADTLKDLNYDDHGLAVVYADQGFHYVNRKGRSLPVLTWDNGP
                     ETPQEGLLRARVGNRVGYFDLKFRQVVPGTFDFGWPFQDGVAEVCNGCRRGTPDADGHT
                     PMEGGERFRIDRSGRRVK"
     gene            8428..9714
                     /gene="tilS"
                     /locus_tag="A7326_RS15230"
                     /old_locus_tag="A7326_15085"
     CDS             8428..9714
                     /EC_number="6.3.4.19"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tilS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418067.1"
                     /locus_tag="A7326_RS15230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15085"
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="WP_198360808.1"
                     /transl_table=11
                     /translation="MTAFPALVPLDAPLLVGYSGGIDSTVLLHWLWRCAQASGTALRAV
                     HVHHGLQPDADDWVLHCQQQCEAWGIELAVHRVQVDNRAGLGLEGAARQARRAAFAAEL
                     RDGETLALAQHLDDQAETFLLRALRASGVDGLAAMSTHSRLGEHPLWRPLLAVPRSALI
                     DHAHQHALHWIEDPSNGDDQADRNFLRLQVLPLLRQRWPHAAAALAGSAMHCGQTRELL
                     DEEDAELIAHLEVAPRVLSLQLLRQVSPGRAARVLRAWVAGHGAAPLPATVLQQALHEL
                     LPADNDRQARVSWHDHAIQQWRDHAYLLPAQLPALPLQWQVEWDGRAPLPLPDGGQLRL
                     QGTPAFERPLQVRARVGGERILLPGRQHSHALKDCLQREHLAPWRRAQLPLIFDGPQLL
                     AAADVVIAAPLHAWLQAHDAQLQWRPGGW"
     gene            9751..10011
                     /locus_tag="A7326_RS15235"
                     /old_locus_tag="A7326_15090"
     CDS             9751..10011
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410522.1"
                     /locus_tag="A7326_RS15235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15090"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_005410522.1"
                     /transl_table=11
                     /translation="MAKKSPENASPVAQFEQSLESLEQLVEQMETGELSLEASLSAYER
                     GVGLYRQCQQALEQAELRVRLLSDPAQPEASEPFDPPSHDG"
     gene            10001..10879
                     /locus_tag="A7326_RS15240"
                     /old_locus_tag="A7326_15095"
     CDS             10001..10879
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264747.1"
                     /locus_tag="A7326_RS15240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15095"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_088026699.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.4e-65, bitscore:
                     217.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEVLFARWRDRIESQLDAALPSPAEAPQRLHQAMRHSVLGGGK
                     RMRPLLVYASGHLFGAQPESLDAAAMSVELIHAYSLVHDDLPAMDDDALRRGKPTTHIA
                     FDEATAILAGDALQTRAFGLLADAPVPATLRVACLQTLAHASGASGMCGGQALDIDATG
                     QQQTLAALTRMHALKTGALIRAAVRMGALCGQAHEPQLAQLDSFADALGLAFQVRDDIL
                     DVEASSEQLGKTAGKDQAQDKSTFPALLGMDGAKAQLHELAARMQAILAGYGEEADALR
                     ALATLAVERDH"
     gene            complement(10992..11363)
                     /locus_tag="A7326_RS15245"
                     /old_locus_tag="A7326_15100"
     CDS             complement(10992..11363)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647933.1"
                     /locus_tag="A7326_RS15245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15100"
                     /product="DUF4870 domain-containing protein"
                     /protein_id="WP_014038018.1"
                     /transl_table=11
                     /translation="MSEFDNVPPPPATTEAPADQRTMALAAHLLGIFTWFIGPLIIWLI
                     NKDDASKAFVTDQAKEALNFQITITIAMLICIVLTIVIIGGILAPIVGILNLVFCIIAA
                     VKANNGEAYRYPFALRLVK"
     misc_feature    complement(11384..11399)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.39"
                     /tool="antismash"
     gene            complement(11451..12818)
                     /gene="pmbA"
                     /locus_tag="A7326_RS15250"
                     /old_locus_tag="A7326_15105"
     CDS             complement(11451..12818)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pmbA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019662101.1"
                     /locus_tag="A7326_RS15250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15105"
                     /product="metalloprotease PmbA"
                     /protein_id="WP_088026700.1"
                     /transl_table=11
                     /translation="MNVIAPEVAVGDDSPARLERLADLSQQLLDRARALGASQAEVSCS
                     EDRGLEVNVRLGEVETVQSTRDRGIAVTVYFGQRKGSASTGDLNEASLAATVEQACAIA
                     RHTEDDPAAGLAEAALMATDFPDLDSWHPWALQADEAVDIALACENAGREADAQIRNSD
                     GASVSSMQSLSVYANSHGFFGRERGTHHSVGCALIAGQGDGMQRDGWYTSALAREDLEE
                     VGLVGRRAAERTVARLQPRSMATGSMPVLFAPEVARSLVGHLLSAVSGGALYRQASFLL
                     DSVGQQLFPDWMQIEELPHLRRGLRSAAFDGDGVGTRASALVRDGVLQRYVLGSYSARK
                     LGLQTTANAGGVHNLQLAANAGSLQEIARQMGDGLLVTELMGQGVNGVTGDYSRGAGGF
                     RVENGEIQYPVDGITIAGNLREMFSSIEAVGSDVDPRSHIRTGSILLGRMTIAGND"
     misc_feature    12862..12871
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.42"
                     /tool="antismash"
     misc_feature    12863..12876
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.54"
                     /tool="antismash"
     gene            12887..13474
                     /gene="yjgA"
                     /locus_tag="A7326_RS15255"
                     /old_locus_tag="A7326_15110"
     CDS             12887..13474
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yjgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338623.1"
                     /locus_tag="A7326_RS15255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15110"
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="WP_088026701.1"
                     /transl_table=11
                     /translation="MRGRDEETGEFHDKSRSQNRRDALDVLALGEKLVSLTPAQLARLP
                     IPEDLLPHIAECKRISAHIAHKRQLAFLAKHMRREEDATLDAIRDALDANSETGRREVA
                     MMHRVEDWRERLLAEGDKALAALLDDYPQADRQQLRTLVRNAQAEKAKNKPPRAYREIY
                     QVLRALMLPAALGLKASAEDADPIENDEADED"
     gene            complement(13516..14961)
                     /gene="tldD"
                     /locus_tag="A7326_RS15260"
                     /old_locus_tag="A7326_15115"
     CDS             complement(13516..14961)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="tldD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007972594.1"
                     /locus_tag="A7326_RS15260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15115"
                     /product="metalloprotease TldD"
                     /protein_id="WP_088026702.1"
                     /transl_table=11
                     /translation="MTDIALTLAQDRLLRPGGLDTAGLERTFGQLLGPGVDFGDLYFQH
                     ARRESWSVEDGIVKDGAHSIEQGVGVRAIAGEKTGFAYSDDIHADALLAAAQSARAISR
                     EGGAQTGRSLLRGNARALYPALDPIDGVGNEAKVEVLKRLDGYLRAADPRVKQVMVSLS
                     GGVDTVLIARSDGVLGADVRPLVRLNVQVIVEHNGRRESGYAGGGGRYGYEELFADGRP
                     EAFAREALRQALVNLEAVPAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYA
                     GRIGERVAAPGVTIVDDGTLDGRRGSLNIDDEGHPSQCTTLIEDGILVGYMQDSLNARL
                     MGVAPTGNGRRESFAHMTMPRMTNTYMRAGQHDPQEMIRSVKKGLYAVNFGGGQVDITS
                     GKYVFSATEAYLIEDGRITTPVKGATLIGNGPETMQKVRMVGNDLALDEGVGICGKDGQ
                     SVPVGVGQPSLLIEGITVGGTQA"
     gene            complement(15022..18879)
                     /locus_tag="A7326_RS15265"
                     /old_locus_tag="A7326_15120"
     CDS             complement(15022..18879)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647937.1"
                     /locus_tag="A7326_RS15265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15120"
                     /product="YhdP family protein"
                     /protein_id="WP_088026703.1"
                     /transl_table=11
                     /translation="MSAPPRLRLRRIRRHFIAACAVGLVGLALLVGTLSQLLPLAERHP
                     DKIAAWLSERAGQPVRFDQLQTAWTRRGPLLQLKGLRIGAGRGLAIGEAEVLVSMYSGM
                     LPGRSLTELRLRGLALDLQQGEDGRWSVRGLPKSDTGGDPLDALRRLGELQVIDGRLGV
                     HAPGLGIDTTLPRIDLRLRVNGDRLRVGVRAWAQTDALPLTAVLDVDRARGNGQAWLGA
                     DPVDFHAWSPLLAAGGVRLREGKGELNLWMTLRDFAPVALTTDSDLRDVRIDGAPMPDV
                     ATPQLQLQRLQARLRWQRQADGWALQVPRLRLKTEDGEQRLDGLQLQVGRQLRVSSGEV
                     QAGTALRALALSDRLEPGLRHWLFLSKPQLDVRELQLAGERDGALWAQGELQSLGFASV
                     GHSPGLRGLGGRFEGDADGFSLQLQPQRQLQFDWPTGFGVRHDLHLAGQVVGWRDEGGG
                     WRIGTAAMRVEGTDYAADVRGGVWFQGDGTRPWLQLAAKLDDVPMTAAKRFWIHSKMSK
                     GATDWLDMALAGGQVRNGVGLVSGDLDDWPFDNNDGRFEATGHITNGDIRFQHDWPLMS
                     QVDADIAFIGPGFDMRGRGDLAGVAVQKFEAGIPDFGQRPLYVRADALSEAGKLLSMLR
                     QSPLHKDYGDTLDNLTAAGPAHVTFDLLQPLHLDEGEGHLQGTVDLNGVKLVDKRFQLT
                     FDNMHGQARYSNGGFGAEELAVRHLGQDGRLSLRAGGYVHDSKLAFESQLSANLDAGVL
                     IDRAPEMAWLKPYIAGTSPWTVAVNLPKVAPGAPAPPSELRLSSDLVGTRLDLPAPLDK
                     PAAEPLATTVAAQLPMGAGRIDVAFGQRLALAARSHNNQTGVQVTLGSDHVDREPPPSG
                     LTVNGRSPTLDALEWISLARGGGDDDGMPLRAVDVQVGKLMLIGGVFEQTRLKLQPGPQ
                     ALDVRLDGPSLAGHLTVPNAEGGTISGQLDRVHWQSLPAAPGAPAAPARVQSGANDMDP
                     AKLPPFALDIADLQFGEVVLGQAVLRTRPLANGLNVDELRFRAPDQEIDISGRWLGRTG
                     GARTELTAQVRSEDLGGLMQNLDYGGQLRGGSGQAQLQASWSGGPSDFQLATLQGRLDL
                     HARNGQLLELEPGAGRVLGLLSVAQLPRRLMFDFRDFFSKGFAFNQVDGSVQFGQGMAR
                     TDKVLIEGPAANITIRGQADLRNQQFDQTIDVNPRAGNLLTVVGAVAGGPVGAALGAAT
                     NAVLSKPLGEIGARTYKVTGPWKEPKVEVIERNRDKTPPAPTPAPAVPPTVTDLPRSRS
                     R"
     gene            complement(18910..20397)
                     /gene="rng"
                     /locus_tag="A7326_RS15270"
                     /old_locus_tag="A7326_15125"
     CDS             complement(18910..20397)
                     /EC_number="3.1.26.-"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rng"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002802933.1"
                     /locus_tag="A7326_RS15270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_15125"
                     /product="ribonuclease G"
                     /protein_id="WP_049444954.1"
                     /transl_table=11
                     /translation="MSEEILVNVTPRETRVAVIENGMLQELHIERGWRRGVVGNIYKGK
                     VQRVMPGMQAAFVEVGLERAAFLHANDVVRPAPVASADTENTTLPPPSSVPIVELLRDG
                     QDIVVQVVKDPIGTKGARLTTQISIPSRYMVLLPQSKVVGVSARIEDEGERARLKALVT
                     ELSAQHGGYGYIVRTNAEGQPAEAIAEDIAYLSRVWNVVERRGREAPSCSNIYEDLSLP
                     LRSVRDLIRKDVDKVKVDSKETFAQLQAFVAKYMPVLAEKLELYSGDRPIFDMFGVEDE
                     IGRALDKQVPLKSGGYLVIDQTEAMTTIDVNTGSFLGQRNLEETVFRTNLEAAQAVARQ
                     LRLRNLGGIIIIDFIDMDDAEHRRQVLRTLEKALARDHAKTTVYDFSPLGLVEMTRKRT
                     VESLERQLSETCPQCSGRGSIKTTETVTYEIFREITRAVRQFDAARLLVIASTKVVARI
                     TDEESSAVAELEEFLGKSIRFQADEQYLQEQFDVVLL"
ORIGIN
        1 atagtccaga ccgcgcgcct cgaattcgca gtccagcgca tgcgtctgca cccactgcgc
       61 caggcgcagc cgtgaatcat tcaacagtgc gccgcgtgcc cgcgtggagt gcagccagtc
      121 acgcgcgttg cagcgcgccc cgaactgcag cagccaacgc cacaatgcag ggtccaggcg
      181 cgtacgcacg tacaacggcg cacgcggatc gagcatccag cgcagcgcac gcaacggcac
      241 gccgggggcc gccagcggtg gcgcatggct gggcgtgacg gtgccgcagt tgccatgcga
      301 cgtcgcgccg ccgacgcgcc ctcggtcgat cacccgcacc tgccggccct gcgcgcgcag
      361 cgccagcgcg gcggccagtc caatggcacc ggcgccgacc acgatcacat cctcgcgcgc
      421 gccctgcatc gatcagccct gcccggcccc acgccgcatc ggcggccact gccggtaggt
      481 catcgcacgc cacaaccatt ccatgggccc gaaacggaag cggcgcaacc agacgtgcga
      541 aagggcgacc tgcacggcaa acaacagcag cgcgaacagc aattgcacgc tgcgcggcat
      601 cagcccgaag ccgcccaggc catagtggta gaacaaccac gtgcacagca gcgactggcc
      661 aagataatgg gtcagtgcca tgcgccccac cggggccagc caggccaacc gcgcacgcca
      721 gtgcacgatc cacgccaggt aacccaggca catcggcagt ccgccgatcg tcaccagtgc
      781 cattgcggct gtcaccggca ggtcgtaggc ccccggtgcc aggtaaggct tccaagcaac
      841 accgatcaac gtgaccagca ggcccagcgg caacgcgatc cagcgcagcg acgcatacag
      901 ccgcgggaag cgctccggcg ccgccagcgc accactgccg gcgaaccagc tgccgatcag
      961 gaacatgccc aacacttccg ggccggtgat caacagcgcg cccatcgacg tgctgaactc
     1021 gctcagccgc tgcacattgg cctgcatcca gctgccctgg ccatagacct ggcgctgcag
     1081 ctcgatgctc tgctgcgcgt cggtgagcat cttctgcacg tcttccaccg aagccatcga
     1141 caccatcgcg ccgaccagca gcatcatggc cacgccgccc agatagacga tcacgcccat
     1201 ccatggcaac cagctgcgtg gtgcctctcg gcaggccagc aacggaagcg agatcagcgc
     1261 atacatcacc aggatgtcac cggaccagac cagcagcgcg tggcacaggc cgatcagcag
     1321 cagcccggcg ctgcggcgca ggtagaacgg ggtgaagtcg cgtccggcca cttcggcgcg
     1381 ttgcgccatc accgcaaagc cggcgccgaa cagcagcgag aacagggtga agaacttgcc
     1441 ctgcacgaac acgtagacga aggcatcggc ccagtagtcg ataccctgcc agtgcacgtc
     1501 gatgcccgtg aaggccagat ccagcggtcc gctgaaggcc tcgatgttca tcagcaggat
     1561 gcccagcagc gcggcaccgc gcagcacgtc caacacggcg atgcgttcgc cggaagccac
     1621 cggctgcagg gaaggagaag cggcgttcac ggggcgtccg tcaggcaggt ccgccattat
     1681 gccgccggcc cacacgccat ggatggccgc gtcgtgttcc agaaacgcaa cggcccgcca
     1741 aagcgggcca ctgctgccat cacgatcgcg ctgcaatcag tggtggtggc cgccgtcgcc
     1801 gtggacgtgg ccgtggtcga tttcttcctg gccggcttcg cgcacgtcaa cgatttcgac
     1861 gtcgaaatgc aggtccttgc cagccatcgg atggttcagg tcgacgtcga cgacgctcat
     1921 gccgaccttc tgcacggtca ccgcacgcgg gccgaagttg gtctgcagca cgacctgctg
     1981 gcccggagcc agcttggtgt tgccgaagtg cttcttcggc acgcgctggg acaggccctc
     2041 acgacgctcg ccgtaggcat cggccgcctt gacgtcgacg ttgaaggtcg cgccggcttc
     2101 cttgtccatc atggcgtttt ccaggcccgg gataatgttg ccgtgaccga tcaggatcgc
     2161 cagcggctcg ccgcggtcct tggacgattc gatcggctcc tggccgactt cggaaacggt
     2221 gtagtggaag cggacaacgc ggtctttttc gatcttcatg cgcaactctg tctggatctg
     2281 ccggaggcag gcgggttggg gcgggttgtc gcccggcggg gacgccgcca tcatgacggc
     2341 caatcctaag gtggcgcatt atccggagat catgcacatc acgccagttt cgtccggcct
     2401 gcgccggctc ctcgccccgg ccctgctgct ggccctgccc gtgctgatga ccgcctgcgg
     2461 cggcggcaag gtcacccgac ccgcgccgcc cccgccgacc gcgaactggc cgaagaccgt
     2521 gccggacaat cccgaggcgg caaactcggt gctgatgcgc gccatcagcc tggtcggcac
     2581 cccctatcgc tatggcggca atacccccga ctccggcttc gactgcagcg gcctggtggc
     2641 ctacgtctac cgcgagatgc tggacctgaa actgccgcgc acgtcgcgcg acctggcggc
     2701 ggtacagggc ccgaagatcg acccgcagcg cctggccacc ggcgacctgg tgttcttcgg
     2761 cagccgcggc agcgtcaccc atgtcggcat ttatgtgggt gaagggcgct tcgtgcacgc
     2821 gccgagcacc ggtggcacgg tccggctgga ctcgctcagc ggtccgtact ggaaggacca
     2881 ctacaccggg gcgaaacgcg tccttcgcta agatgaacag gcgatatgtt caaaactgtg
     2941 acgttcatca cccacaaact aacgatttac taacggaatt tttaacttat tgccgctttt
     3001 acagggcatg atgccccatc gtttttttcc tgtgaccgac gcgtgacgac tgacgacctg
     3061 aaaagcgaag gccagacttc cgtatcttca cgtagtgccc gcccgctgtt gcttggcttg
     3121 gcactgtgtc tgaccagcct tccggcctgg tcgcagactg ctccgaaccg ttccgatgtg
     3181 accccggccc cggtggccga gagcaccgcc cgaccggcca ccaaggccga ggctgctgcc
     3241 ccgcagcgca gccgcgtcga tgccgccgcc agcgccacgc tggccgccct gctgccgcac
     3301 ctggccgcca atgacaccat tccgctgatg gaccgctcgg ccgtggtggc cggcgacctc
     3361 agccgcctgc ttgccaacta cgacaccagc agcgctgcca atggcagcgt tgtcggcacc
     3421 gccgccgaca acggcaaggt gcagtcgctg ctgcgccgcg cgatgaccct gctgggcacc
     3481 ccgtaccgtt ggggtggcag caacccggac agcggcttcg attgcagcgg tctggtcggc
     3541 tacgtgttcc gctcggccct gggcatcgag ctgccgcgcg tctcgcgcga gatggcccac
     3601 gatgacaagg ccgaactgat caacgaccgc actgcactgg ccgcaggtga cctggtgttc
     3661 ttcggccgca agggccgtgt tgaccacgtc ggcatctatg tcggcgacgg ccgcttcctg
     3721 cacgcgccga gctcgggcaa ggacgtccgc gtggacaccc tgctcagtgg ctactggggc
     3781 aacaagttca tgcaggcccg ccgggtcgac ctctgacccg ctggcgctac ggcgccgcct
     3841 gaaagacaga aagccgctgc cctgcagcgg ctttttttgt tggccccgtg caattggtgg
     3901 gtagcggccg accttggtcg gcactgtcgc catccacgca tggcgtggat ctactgtggc
     3961 cccgcctgag tcggctcctc cgatcaggcg ggtgcctgcc ggtgggtgcc gaccttggtc
     4021 ggcaccgcct tcatccacgc atggcgtgga tctaccaggg cccaccttgg ccgccaccgc
     4081 gccagccagc tcccaaacaa aaaagcccgc cggtcagggc gggcctttca tctccacgca
     4141 acctcagccg cgtggcggag tcgggtcagg atcgtccaca cccacattgc tggacgggtt
     4201 gtcatacacc gcctggtcga gcagcccggt ttccttggcc acgatcaccg gcaccagcat
     4261 ctggccggtc acgttcgtca tcgtgcgcat catgtccagg atgcggtcga tggcatacag
     4321 gtagccgatg gtctccagtg gcaggttggc cgcgctcagc accaccgtgg ccatgatcac
     4381 cgccgtaccc ggcacgccgg ccgtaccgaa gctgcccagc accgaggcga tcaacaccac
     4441 cacatactgt tccggggtca gcggcacgcc gctgtactgc gcgatgaaca ccgcgcacag
     4501 cgccgggtag atcgcaccgc agccatccat cttgatgctg gcgcccagcg gcaccgcgaa
     4561 cgaaccgtag tccttgttca cgcccaggtt gtgggtgatc gaacgcagcg ccaccggcat
     4621 cgcggcgaag ctggacgagc tgacgaaggc gacctgcatg cccggcgccg cgccacggaa
     4681 gaacttcagc ggattcaggc cgtgcgccag cagcagcgcg ctgtagacca ctacgatgtg
     4741 cagggcgcag gccacgtaca gcgccagcac gaaatgcccc agcggcagca gcttctcgaa
     4801 gccatagctg ccgaccaggc cggcgatcag gccgaaggtg ccgatcgggg tgacttccag
     4861 cacgaagcgg gtcacctgga tcatgatgtc gctcatctgg ccgaccagct tgcgagcctc
     4921 ggtcaccttc tcgcccagct tgacgatggc aaagcccacc aggccggcga agaagatcac
     4981 cggcaggatc gagccacgtc cggcggccag cacggtttca cccgctgcgt tgaccttggt
     5041 gccgatgccg gacagcgcat agaagacatt ggccggcacc acgtccagca gcacctgcac
     5101 cacgctgggc acttcgcgcg gcacgtagtt gctggccatg gtcagttgca gaccaccggc
     5161 gccgggctgc agcacggtgc ccacgcccag gccgacgcac accgccagcg cggcggtgat
     5221 cacgaaccaa aggaaggtgc ggccactgag cgcggcgacc gacttctggc cgtgcagcga
     5281 cgagatcgcg ttgatgaccg cgaagaacac cagcggcacg gcgatcatct tgatcagggt
     5341 gacgtacagc tcgccgagcg ggccgaacca cgtttccgcg gccgggccga gcgcccagcc
     5401 ggccagcgcg ccgagcacga agccaccgac cacgcgctgc cagaatggaa tccgcagcca
     5461 ggcagagacc agcttcatag gcaatccaga ggggagggaa gggatgctgg cacgatagcc
     5521 caaggcggcc cgcagaacga ccgcccggcc ggcaaatcag tgtgtcatcg gcgtgccttg
     5581 cggggccggg cataatgaac gtcccgttac agtttgtgag atcccagcgt ccatgcgccg
     5641 ttccgtctcc ctgttggccg cctgcgccac caccctgctg ctgggcgcct gcgccagcac
     5701 cgcccccgca tccgccccgg ccggcctgaa ggtcgccgtc gatcccgtcg tccatccggc
     5761 cggcgagacc ccgcagtggt ggtaccgcag tggcgccgcc caggccgccg ccaacggcgc
     5821 gatgtccggc aaggccaaga acgtcatcct gttcctcggt gacggcatga gcctgaccac
     5881 cgtggcggcc tcgcgcatct acgaaggcca gcagaagggc ggctcgggtg aggagaacct
     5941 gctgtcctgg gagcgcttcc cggccacggc gttcagcaag acctacaaca ccgattcgca
     6001 gaccccggat tcggccggca ccatgaccgc catcaccacc ggcgtgaaga cccacatggg
     6061 cgcgatcggc gtcagcgccg gcagccgcac cgactgcgcc gacagcctgt ccaagggcct
     6121 gctgacctgg ctgcaactgg ccgacagcgc cggcctggcc accggtgtgg tgtccaccgc
     6181 acgcctgacc catgccaccc cggccgccac ctacgcgcac tcgcccgagc gcaactggga
     6241 aaacgacacc gacctgactg aagccgccaa ggcggccggc tgcaaggaca tcgcccagca
     6301 gctgctgtcg acctcgcgct atggccgtgg cccgctggtc gccctcggcg gcggtcgcgg
     6361 tgaattcacc acggtggaag agcgcgaccc ggaatacgac gacaaggtcg gccagcgcct
     6421 ggatggccgc agcctggtgc aggaatggca gcaggcgcac ccgcagggtg cctacgtgtg
     6481 gaacagcaag cagctggccg ccgccgccaa cgcgccggcc atccttggcc tgttcgagcc
     6541 ggaccacatg cgctacgagt acgagcgccc gcaggacccg ggcggtgagc cgagcctggc
     6601 cgaactgacg gctgcagcca tcaagaatct ggccaagcac caggaaggct acgtgctgat
     6661 gatcgaaggc gcgcgcatcg accacgccaa ccacagcggc aacgcctacc gtgccctgac
     6721 cgagaccgtg gccctgtccg acgcggtgcg cgtggccaat gaactgacct cggccgacga
     6781 caccctgatc atcgtcaccg ccgatcactc gcacacgctg aacttcgtcg gctacccggc
     6841 acgcggcaac ccgatcctgg gcaaggtgaa ggacaagggc ggcgaagacg gcgccggcaa
     6901 gctggactat gcactggacg gcagcggcca gccgtacacc acgctgagct acgccaacgg
     6961 cccgggccat accggcagca gcaaccagca gccggccggt ccgaagcgct acccgcacaa
     7021 cccgagcagc ttcgaaccgg ccaacggtcg cccgaacctg cgcgagatcg acaccgagca
     7081 tccggactac atgcaggaag cactggtgcc gatgaagtcc gagtcgcatg gcggcgaaga
     7141 cgtcggtatc tgggcacgcg gcccgggcag caaggcgatc cgcggcacgc tggaacagaa
     7201 cgcgatctac cacatgatcg tgcaggccac cccggccctg cgcgagcgcc tgtgccaggc
     7261 cggcacctgc gatgacaagg gcgtgccggt gcagctgccg gcaccgacgg ccttcgaacg
     7321 caaggccgaa gccaagtgat cacacggcag gcccgccctg cccccgccag cggccgcttc
     7381 gcgcggtcgc tggtcctgct tggcgtgctg gtcagtgcca atgcagcggc acaggcaccg
     7441 gcgtgcaagc tgctgaccga cgaacacggg ttgtggccgc tgcccaactg cgaagtggtc
     7501 gatcaccggc cgaagatcag tgccgacacc ttgaaggacc tgaattacga cgaccatggc
     7561 ctggccgtgg tgtacgccga ccagggcttc cactacgtca accgcaaggg ccgcagcctg
     7621 ccggtactga cctgggacaa cggtccggaa acaccgcagg aaggcctgct gcgcgcccgt
     7681 gtcggcaacc gcgtcggcta cttcgacctg aagttccgcc aggtggtacc cggcaccttc
     7741 gatttcgggt ggccgttcca ggatggcgtg gccgaggtct gcaacggctg ccggcgcggc
     7801 acgccggatg ccgatggcca cacgccgatg gaaggcggag agcggttccg catcgaccgc
     7861 tctggccgtc gggtgaagta ggtttttcgg cagggctgcg ccctgcacct gccgaagccg
     7921 aagccaaatc gagatcaaaa gcggctctgg ttttctgtga gttgggcggg gcggtgtggg
     7981 tggtcaggac acgccgtaaa cccgtccatg ggggctcgat ggcgccatcc atggcgccaa
     8041 cggtcctgcc cacccacacc gccccacccc cgacagattt ccggtgacgg ttggaccatc
     8101 cacgccatgc gtggatcaga tctgtcagat atcgaattga atccggggtc agatccgttt
     8161 tccgcaggaa aacggatctg accccatcaa catgcccaac agctcgcagg aaactgtcga
     8221 aggcggggtg ggtccggttg cgggagtgtc cgcggcatgg atgccgcggc caagccccca
     8281 tggacgggtt aacggcgtct cccgcaaccg gacccacccc gccaaccctc aggaaaccag
     8341 ctgttgctgt tgcttcggcc gttgccgttg cttgcgcgtc tgcgggtgca gggcgcagcc
     8401 ctgccgacca accctatact tgccgccgtg actgccttcc ctgcccttgt tccgctggat
     8461 gcgccgctgc tggtgggcta cagcggtggt atcgactcca ccgtgctgct gcactggctg
     8521 tggcgctgcg cccaggcctc cggcacggcg ctgcgcgcgg tgcacgtgca ccacggcttg
     8581 cagcccgatg cggatgactg ggtgctgcac tgccagcagc aatgcgaggc ctggggcatc
     8641 gaactggccg tgcatcgcgt gcaggtcgac aaccgcgcgg gcctcggcct tgaaggcgcg
     8701 gcgcggcagg cacgacgcgc cgcgttcgcg gcggaactgc gcgacggcga aacgctggca
     8761 ctggcgcagc acctggacga ccaggccgag accttcctgc tgcgcgccct gcgcgcgtcc
     8821 ggcgttgatg gcctggcggc gatgtccacc cacagccgcc ttggcgaaca tcccttgtgg
     8881 cgcccgctgc tggcggtacc gcgcagtgcg ctgatcgacc atgcccacca acatgcgctg
     8941 cactggatcg aagaccccag caatggcgac gaccaggcgg atcgcaactt cctgcgcctg
     9001 caggtgctgc cattgctgcg ccaacgctgg ccgcatgccg ctgcggcgct ggcgggcagc
     9061 gcaatgcact gcgggcagac ccgcgaactg ctcgatgagg aagacgccga gctgatcgca
     9121 cacctggaag tcgccccacg cgtgctgtcg ctgcagctgc tgcgccaggt ctcaccgggc
     9181 cgtgccgcac gcgtgctgcg tgcctgggtg gccggccacg gtgcggcgcc gctgccggcc
     9241 acggtgctgc agcaggcact gcacgagctg ctgccggccg acaacgatcg tcaggcccgt
     9301 gtgagctggc acgatcacgc gatccagcag tggcgcgacc acgcctacct gctgccggcc
     9361 cagctgcctg cgcttcccct ccagtggcag gtcgaatggg atggacgcgc accgctgccg
     9421 ctgcccgatg gcggacagct gcgcctgcag ggcaccccgg ccttcgaacg cccgctgcag
     9481 gtccgtgcac gcgtgggcgg tgagcgcatt ctgctgcccg gtcgccagca ttcgcatgcg
     9541 ctgaaagact gcctgcaacg cgaacacctc gccccctggc gacgcgcgca gctgccgctg
     9601 atctttgatg gcccgcaatt gctggccgcc gccgacgtgg tcatcgcggc ccctctgcac
     9661 gcctggttgc aggcccatga tgctcagctg cagtggcgtc ccggcggctg gtgaattgac
     9721 ccccgcgcgc ggcccgtcca cacttgccac atggccaaga agtcccccga aaacgcctcc
     9781 ccggttgccc agttcgagca gtcgctcgaa tcgctggaac agctggtgga gcagatggaa
     9841 accggcgagc tgagcctgga agcctcgctc agtgcttacg aacgtggcgt cggtctgtat
     9901 cgccagtgcc agcaggcgct ggaacaggcc gaactgcgcg tgcgcctgct cagcgatccg
     9961 gcgcagccgg aagcatccga acctttcgat ccacccagcc atgacggctg aggttctgtt
    10021 cgcgcgctgg cgcgaccgta tcgaaagcca gctcgacgcc gctctgccct cgcctgccga
    10081 agcaccgcag cgcctgcacc aggccatgcg ccattcggtg ctgggcggtg gcaagcggat
    10141 gcgcccgctg ctggtgtacg ccagtggcca cctgttcggt gcgcagccgg aaagcctgga
    10201 tgcggcggcc atgtccgtcg agctcatcca cgcctactcg ctggtgcatg acgacctgcc
    10261 ggcgatggat gatgacgcgc tgcgccgtgg caagccgacc acccacatcg ccttcgacga
    10321 agccaccgcg atcctcgccg gcgacgccct gcagacccgt gccttcggcc tgctggccga
    10381 tgcaccggtg ccggccacgc tgcgcgtggc ctgcctgcag accctggccc acgcctccgg
    10441 cgcgtccggc atgtgcggcg gccaggcgct ggatatcgat gccaccggcc agcagcagac
    10501 gttggcggcg ctgacccgca tgcacgcgct gaagacgggc gcgctgatcc gcgcagcggt
    10561 gcgcatgggc gcgctgtgcg gtcaggccca cgaaccgcag ctggcccagc tggacagctt
    10621 cgccgatgcg ctcggcctgg ccttccaggt acgcgacgac atcctcgatg tcgaggccag
    10681 ttccgagcag ctgggcaaga ccgccggcaa ggaccaggcg caggacaaga gcaccttccc
    10741 cgccctgctc ggcatggacg gcgcaaaggc ccagctgcac gagctcgcag cgcgcatgca
    10801 ggcgatcctg gctggatacg gcgaagaggc cgatgcactg cgtgcgctgg cgacgctggc
    10861 ggtcgaacgc gatcattgat cgctggtggt gatgctgccg cgctgcgcgc tcgccgggca
    10921 tggcccggcg ctaccgtcaa gcaaaaacgc ccggcaatgc cgggcgtttt cagttccgca
    10981 tgcagctggt tttacttgac caggcgcagc gcgaacgggt agcggtacgc ttcgccgttg
    11041 ttggccttga ccgctgcaat gatgcagaac accaagttca ggatgccgac gatcggggcc
    11101 aggatgccgc cgatgatcac gatggtcagc acgatgcaga tcagcatcgc gatggtgatg
    11161 gtgatctgga agttcagcgc ttccttggcc tggtcggtca cgaaagcctt gctggcgtcg
    11221 tccttgttga tcaaccagat gatcagcgga ccgatgaacc aggtgaaaat gcccagcagg
    11281 tgcgcagcca gcgccatggt gcgctggtcg gccggggcct cggtggtggc cggcggcggc
    11341 gggacgttat cgaattcgct cacgacaaaa ctccttttca ttgggtggtc ttgaccaacc
    11401 agcacccagc tggttgcgtc aggcgggcat agcttacgcc atcaatacca tcaatcatta
    11461 ccggcgatgg tcatccgccc cagcaggatc gagccggtcc ggatgtgcga gcgcgggtcg
    11521 acgtcactgc cgaccgcctc gatgctgctg aacatctcgc gcaggttacc ggcgatggtg
    11581 atgccatcca ccgggtactg gatctcgccg ttctcgacgc ggaagccacc ggcaccgcgc
    11641 gagtagtcgc cggtcacccc gttcacgccc tgccccatca gctcggtcac cagcaggcca
    11701 tcgcccatct gccgcgcgat ctcctgcagg gagcccgcgt tggcggccag ctgcaggttg
    11761 tgcacgccgc ccgcattggc ggtggtctgc aggcccagct tgcgtgccga atagctgccc
    11821 agtacgtagc gctgcagcac accgtcacgg accagtgccg aagcacgggt gcccacgccg
    11881 tcaccgtcga aggcggccga gcgcaggccg cggcgcaggt gcggcagttc ctcgatctgc
    11941 atccagtccg ggaacagctg ctggccaacg ctgtccagca ggaagctggc ctggcggtac
    12001 agggcaccgc cggacaccgc cgacagcagg tgaccgacca ggctgcgcgc cacttccggg
    12061 gcgaacagca ccggcatgct gccggtggcc atcgaacgcg gctgcaggcg ggcgacggtg
    12121 cgctcggcgg cacgacgacc gaccaggccc acctcctcca gatcctcacg ggccaacgcg
    12181 ctggtgtacc agccatcgcg ctgcatgcca tcaccctggc cggcaatcag cgcacagccc
    12241 accgaatgat gggtgccacg ctcacggccg aaaaagccat gcgaattggc gtacaccgac
    12301 aggctctgca tgctcgacac cgaggcgccg tcggaattgc ggatctgcgc atcggcctcg
    12361 cggccggcgt tttcacaggc cagggcgatg tccaccgcct cgtcggcctg cagcgcccaa
    12421 gggtgccagc tgtccaggtc ggggaagtcg gtcgccatca gcgccgcctc ggccaggccg
    12481 gcggccgggt cgtcctcggt atggcgggca atcgcgcagg cttgctcgac cgtggcggca
    12541 aggctggcct cgttcaggtc gccggtgctg gcgctgccct tgcgttggcc aaaatagacg
    12601 gtgacggcaa taccgcggtc gcgggtggac tgcacggtct caacctcgcc aaggcggaca
    12661 ttgacctcca ggccacggtc ctcgctgcag ctgacctcgg cctggctggc gcccagcgca
    12721 cgggcacggt cgagcagctg ctgggagagg tcggccagcc gttccagccg ggccgggctg
    12781 tcgtcgccga cggccacttc aggggcgatc acgttcaatg ctttatcctg tacgggttgg
    12841 gcccggcatc acgccgggcg actttttttg agatcaggta ggaacgatgc gcggacgcga
    12901 cgaagaaacc ggtgaattcc acgacaagag ccgcagccag aaccggcgcg acgcgctcga
    12961 cgtcctggcc ctgggcgaga agctggtgtc gttgaccccg gcccagctgg cgcgcctgcc
    13021 gattccggaa gacctgctgc cgcatatcgc cgagtgcaag cgcatcagcg cccacatcgc
    13081 ccacaagcgc cagctggcgt tcctggccaa gcacatgcgc cgcgaagaag acgccacgct
    13141 ggatgcgatc cgcgatgcgc tggacgccaa cagcgaaacc ggccgccgcg aagtggcgat
    13201 gatgcaccgc gtggaagact ggcgcgagcg cctgctggcc gaaggagaca aggcgctggc
    13261 cgccctgctg gacgattacc cgcaggccga ccgccagcag ctgcgcacgc tggtgcgcaa
    13321 cgcgcaagcc gagaaggcga agaacaagcc gccgcgcgcc taccgcgaga tctaccaggt
    13381 gctgcgcgcg ctgatgctgc cggcggcgct gggcctgaag gccagcgccg aagacgccga
    13441 ccccatcgag aacgacgaag ccgacgagga ctgagtgccc gtcggtcggg gcggtggcgc
    13501 tggccatcgc ccggctcagg cctgggtacc gccgacggtg atgccctcga tcaacagcga
    13561 gggctggccg acacccacgg gcacgctctg cccgtccttg ccgcagatgc ccacgccctc
    13621 gtccagggcc aggtcgttgc cgaccatgcg caccttctgc atggtttccg ggccgttgcc
    13681 gatcagggtc gcgcccttca ccggtgtggt gatgcgccca tcctcgatca ggtaggcctc
    13741 ggtggccgag aacacgtact tgccgctggt gatgtcgacc tggccgccgc cgaagttgac
    13801 cgcgtacagg cccttcttta ccgagcggat catctcctgc gggtcgtgct ggccggcacg
    13861 catgtaggtg ttggtcatgc gcggcatggt catgtgcgcg aatgattcgc ggcgcccgtt
    13921 gccggtcggc gccacgccca tcaggcgtgc attgaggctg tcctgcatgt agccgaccag
    13981 gatgccgtcc tcgatcagcg tggtgcactg gctgggatga ccctcgtcgt cgatgttcaa
    14041 cgaaccacgg cgtccgtcca gcgtgccgtc atcgacgatc gtcacccccg gtgccgcgac
    14101 acgctcaccg atgcggcccg cgtagacgct ggtgcccttg cggttgaagt cgccttccag
    14161 gccatggccg accgcttcat gcagcagcac gccgggccag cccgggccca gtaccaccgg
    14221 catcacgccg gccggtgccg gtaccgcctc aagattcacc agcgcctggc gcagcgcctc
    14281 acgggcgaag gcttccgggc ggccgtcggc gaacagctcc tcatagccat agcggccacc
    14341 gccaccggca tagccggact cgcgacggcc gttgtgctcg acgatcacct gcacgttcag
    14401 gcgcaccagc gggcgcacgt cggcgcccag cacgccgtcg ctgcgggcga tcagcaccgt
    14461 atcgacgccg ccggacaggc tgaccatcac ctgcttcacg cgcgggtcgg cagcacgcag
    14521 gtagccgtcc aggcgcttga gcacctcgac cttggcctcg ttgccgacgc catcaatcgg
    14581 gtccagcgcc gggtacagcg cgcgcgcatt gccgcgcagc agcgaacgcc cggtctgggc
    14641 gccaccttcg cgcgaaatcg cacgcgccga ctgtgccgca gccagcagcg cgtcggcatg
    14701 gatgtcatcg gagtaggcga agccggtctt ctccccggca atcgcacgca cgcccacgcc
    14761 ctgctcgatg gaatgggcac cgtccttgac gatgccatcc tccacgctcc agctctcgcg
    14821 gcgggcgtgc tggaagtaaa ggtcaccaaa gtccacaccg gggccgagca actgcccgaa
    14881 ggtgcgctcc aggccagcgg tatccaggcc accagggcgc aacaggcggt cttgggcaag
    14941 tgtcagggcg atatcagtca tggtcctcga tctggggatg cgggggcgtt caggcaagcc
    15001 ccgtgaacgg gaacaccagg ctcagcgtga acgcgagcgt ggcaggtcgg tcaccgtcgg
    15061 cggaaccgcc ggtgccggtg tgggtgcggg cggcgtcttg tcgcggttgc gttcgatcac
    15121 ttccaccttc ggctccttcc atggaccggt caccttgtag gtacgggcgc cgatttcgcc
    15181 caacggtttg gacaataccg cattggtggc ggcgccgagt gccgcaccca ccggcccccc
    15241 cgccaccgcg ccgaccacgg tcagcagatt gccggcgcgc gggttgacgt cgatggtctg
    15301 gtcgaactgc tggttgcgca ggtcggcctg gccgcggatg gtgatgttcg ccgccggacc
    15361 ctcgatcagc actttgtcgg tacgggccat gccctggccg aactgcacgc tgccatcgac
    15421 ctggttgaac gcgaagccct tggaaaagaa atcacggaag tcgaacatca ggcgccgcgg
    15481 cagctgcgcg acactgagca ggccgagcac gcggcctgcg ccgggttcca actccagcaa
    15541 ctggccgttg cgcgcgtgca gatcgagccg gccctgcaga gtggccagct ggaagtccga
    15601 aggaccgccg ctccacgagg cctgcagctg ggcctgaccg gagccgccgc gcagctggcc
    15661 accgtagtcc aggttctgca tcaggccgcc caggtcctca ctgcgcacct gtgcggtcaa
    15721 ctcggtgcgg gcgccaccgg tgcggcccag ccagcgaccg ctgatgtcga tctcctggtc
    15781 gggcgcacgg aagcgcagct cgtccacgtt caggccattg gccagcggcc gcgtacgcag
    15841 caccgcctgg ccgagtacga cctcgccgaa ctgcagatcg gcaatgtcca gcgcgaatgg
    15901 cggcagcttt gccggatcca tgtcgttggc gccggactgt acccgcgccg gcgcagccgg
    15961 tgcgcccggt gcggccggca gcgactgcca atgcacacgg tcgagctggc cgctgatggt
    16021 gccgccctcg gcattgggaa cggtcaggtg gcccgccagc gacggcccat ccaggcgcac
    16081 atccagcgcc tgcgggccag gctgcagttt cagccgtgtc tgctcgaaga cgccgccgat
    16141 cagcatcaat ttgccgacct gcacgtccac cgcgcgcagc ggcatgccgt cgtcgtcacc
    16201 gcctccacgc gccaggctga tccactccag cgcatccagg gtcgggctgc gaccgttgac
    16261 ggtcagcccg ctcggtggcg gctcacggtc aacgtggtcg ctgccgagcg tgacctgcac
    16321 gccggtctgg ttgttgtggc tgcgcgcggc cagggccaga cgctggccaa aggccacgtc
    16381 gatgcggcct gcccccatcg gcagctgcgc ggccaccgtg gtcgccaacg gttcggcggc
    16441 cggcttgtcc agcggcgccg gcaggtccag gcgggtgccc accagatccg aactcaggcg
    16501 cagctcgctg ggcggtgcag gcgcccccgg cgcgaccttc ggcaggttca ccgcaacggt
    16561 ccacggtgag gtgccggcga tgtagggctt cagccacgcc atttccggtg cgcggtcgat
    16621 cagcacgcca gcatcgaggt tggccgacag ctgcgattca aaggccagct tgctgtcgtg
    16681 cacgtaaccg ccggcacgca ggctcaggcg gccgtcctgg ccgaggtggc gcaccgcaag
    16741 ttcctcggcg ccgaaaccgc cgttgctgta gcgcgcctgc ccatgcatgt tgtcgaaggt
    16801 caactggaac cgcttgtcga ccagcttcac accgttgagg tcgaccgtac cctgcaggtg
    16861 gccctcgcct tcatccaggt gcagcggctg cagcagatcg aaggttacat gcgccggtcc
    16921 cgcagcggtg aggttgtcga gggtgtcgcc ataatccttg tgcaacgggc tctgccgcag
    16981 catcgacagc agcttgcccg cctcgctgag ggcatcggca cgcacgtaca gcggccgctg
    17041 gccgaaatcc ggaatgcccg cttcgaactt ctgcaccgcc acaccggcca ggtcgccgcg
    17101 cccacgcatg tcgaagccgg ggccgatgaa ggcgatatcg gcatcgacct ggctcatcag
    17161 cggccagtcg tgctggaagc ggatgtcgcc gttggtgatg tggccggtgg cctcgaagcg
    17221 gccatcgttg ttgtcgaacg gccagtcgtc caggtcaccg ctgaccaggc cgacgccatt
    17281 gcgcacctgg ccgccggcca gcgccatgtc caaccagtcg gtggcgccct tgctcatctt
    17341 ggagtggatc cagaagcgct tggctgcggt catcggcaca tcgtccagct tggccgccag
    17401 ctgcagccag ggccgcgtgc cgtcgccctg gaaccagaca ccaccgcgca cgtcggccgc
    17461 gtagtcggtg ccttccacgc gcatcgccgc agtgccgata cgccagccac cgccctcgtc
    17521 gcgccatccc accacctgtc ctgccaggtg cagatcatgg cgcacaccaa agccggtcgg
    17581 ccaatcgaac tgcagctgcc gttgcggctg cagctgcagg ctgaagccat cggcatcgcc
    17641 ctcgaaacgt ccacccaggc cacgcaggcc cggggaatgc ccaacgctgg cgaaacccag
    17701 cgactgcagc tctccctgcg cccacagcgc gccatcgcgt tcgccggcca gttgcagctc
    17761 tcgcacatcc agctgcggtt tggacaggaa caaccagtgg cgcaggcctg gttcgaggcg
    17821 atcactcagc gccagcgcac gcagcgcggt accggcctgt acttcaccgg aactcacccg
    17881 cagctgcctg ccaacctgca actgcaggcc atcgagccgt tgctcgccgt cttccgtctt
    17941 caaacgaaga cgcggtacct gcagcgccca accatcggcc tggcgctgcc agcgcaggcg
    18001 cgcctgcaag cgctgcagct gcaactgcgg cgtcgccacg tcgggcatcg gtgcaccgtc
    18061 gatgcgcacg tcacgcaggt ccgaatcggt ggtcagcgcc accggcgcga agtcgcgcag
    18121 ggtcatccac aggttcagct cacccttgcc ttcgcgcagg cgcacgccac cggccgccag
    18181 cagcggcgac caggcgtgga aatcaacagg atcggcaccc agccaggcct ggccgttgcc
    18241 gcgcgcgcgg tccacgtcca gcactgcggt cagcggcagc gcatcggtct gcgcccaggc
    18301 acgcacgccc acacgcaggc gatcgccatt gacgcgcagg cgcagatcga tacgcggcaa
    18361 ggtagtgtcg atacccaatc ccggtgcatg cacgcccagg cggccatcga tcacctgcag
    18421 ctcgcccagc cggcgcagcg cgtccagcgg gtcaccgccc gtgtctgact tcggcaggcc
    18481 gcgcaccgac cagcggccgt cctcgccctg ctgcaggtcc agcgccaggc cacgcaggcg
    18541 caactcggtc agcgagcggc caggcagcat cccgctgtac atcgacacca gcacttcggc
    18601 ctcgccgatc gccaggcccc ggccggcgcc gatgcgcagg cccttcagct gcagcagcgg
    18661 gccacgacgg gtccaggccg tctgcagctg gtcgaaacgc accggctggc cggcacgctc
    18721 actcagccag gcggcaatct tgtcgggatg tcgctcggcc agcggcagca gctggctgag
    18781 cgtgcccacc agcagtgcaa gcccgaccag gcccaccgcg caggcggcaa tgaaatgacg
    18841 gcggatcctt cgcagtcgca ggcgcggcgg cgcgctcatc ggccaccgcc ggcctgcagc
    18901 cggcgaggat cagagcagaa caacatcgaa ttgctcctgc aggtactgct cgtccgcctg
    18961 gaagcggatg ctcttgccga ggaattcttc cagctcggcc accgccgaag actcctcgtc
    19021 ggtaatgcgt gcaacgacct tggtcgaagc gatcaccagc aggcgcgccg catcgaactg
    19081 gcgcaccgcg cgggtgatct cgcggaaaat ctcgtaggtc accgtctcgg tggtcttgat
    19141 gctgccacgg ccgctgcact gcgggcaggt ttccgacagc tggcgctcca ggctttccac
    19201 cgtgcgcttg cgggtcatct ccaccaggcc cagcggcgag aagtcgtaca ccgtggtctt
    19261 ggcatggtca cgggccagcg ccttttccag ggtgcgcagc acctggcgac gatgctcggc
    19321 atcgtccatg tcgatgaaat cgatgatgat gatgccgccc aggttgcgca gccgcagctg
    19381 ccgcgccact gcctgcgccg cttccaggtt ggtgcggaac accgtctctt ccaggtttcg
    19441 ctggccgagg aacgaaccgg tgttcacatc gatggtggtc atcgcctcgg tctggtcgat
    19501 caccaggtag ccgccggatt tcagcggcac ctgcttgtcc agcgcgcggc cgatctcgtc
    19561 ctccacgccg aacatgtcga agatcggtcg gtcacccgaa tacagttcca gcttctcggc
    19621 cagcaccggc atgtacttgg ccacgaaggc ctgcagctgc gcgaaggttt ccttggagtc
    19681 caccttcacc ttgtccacgt ccttgcggat caggtcacgc accgaacgca gcggcaggct
    19741 caggtcctca tagatgttgc tgcacgaggg cgcttcgcgg ccacggcgct caaccacgtt
    19801 ccagacccgc gacaggtagg cgatgtcctc ggcaatggcc tcggccggct gcccttcggc
    19861 attggtgcgc acgatgtagc cgtagccgcc atgctgggcc gacagttcgg tcaccagtgc
    19921 cttcagccgc gcccgctcgc cttcatcctc gatgcgcgcg gacacgccca ccaccttgga
    19981 ctgcggcagc agcaccatgt aacgcgaggg aatgctgatc tgcgtggtca ggcgcgcgcc
    20041 cttggtaccg atcgggtcct tcaccacctg caccacgatg tcctggccgt cgcgcagcag
    20101 ttcgacgatc ggcacgctgg acggcggcgg cagcgtggtg ttctcggtgt ccgcactggc
    20161 caccggcgcc gggcgcacca cgtcgttggc gtgcaggaac gcggcgcgct ccagcccgac
    20221 ctcgacgaag gccgcctgca tgccgggcat cacgcgctgt accttgccct tgtagatgtt
    20281 gccgaccaca ccccggcgcc agccgcgctc gatgtgcagc tcctgcagca tgccgttttc
    20341 gatcacggcg acccgggtct cgcgcggggt cacattgacc aggatttcct cagacatcgg
    20401 cagcctccct ggcggcatca gcagtggggg ccggcacgcc gcagcgcgcc agcagacgat
    20461 cggtgtgcag cagcggcagt cccatcacgc cggagtagct gcctgaaaga tgttcgatcc
    20521 agcgctcggc cccgccctgg atggcgtagg ccccggcctt gtccagcggt tcgccggtgg
    20581 ccacgtaggt ggcgatgtcg gcggcgctga tcggcgcgaa ggtcacttcg gaaatgacca
    20641 gctcgctgtc cagcccctcc gcagagacca ccaccaccgc agtcatcacc tggtgggtgc
    20701 ggccggccag ccgggccagc atcacccgcg cgtcggcggc atcggccggc ttgccgaaca
    20761 cttcaccgtc cagcaccacc tcggtatccg agccgagcac gcgcgcctgc gggtcgtcgg
    20821 ccagcacctg ggccaggccg gcacgcgcct tgtcggcggc gacccggcac acgtactgc
//
