LOCUS       NZ_CP015612            10876 bp    DNA     circular CON 05-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain OUC_Est10 chromosome, complete
            genome.
ACCESSION   NZ_CP015612
VERSION     NZ_CP015612.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4668743)
  AUTHORS   Dong,H., Rui,J., Xue,C., Li,X. and Mao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAY-2016) College of Food Science and Engineering,
            Ocean University of China, No. 5 Yushan Road, Shinan District,
            Qingdao, Shandong 266003, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP3 in SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 123x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002138415.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 21:48:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,285
            CDSs (total)                      :: 4,195
            Genes (coding)                    :: 4,163
            CDSs (with protein)               :: 4,163
            Genes (RNA)                       :: 90
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 32
            CDSs (without protein)            :: 32
            Pseudo Genes (ambiguous residues) :: 0 of 32
            Pseudo Genes (frameshifted)       :: 12 of 32
            Pseudo Genes (incomplete)         :: 20 of 32
            Pseudo Genes (internal stop)      :: 6 of 32
            Pseudo Genes (multiple problems)  :: 4 of 32
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:11:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1510936
            Orig. end                         :: 1521812
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP015612.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Strain available from Biochemical Engineering Laboratory, College
            of Food Science and Engineering, Ocean University of China.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10876
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10876
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10876
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5876](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5876)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(1232..1246)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.56"
                     /tool="antismash"
     misc_feature    2451..2471
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.71"
                     /tool="antismash"
     gene            complement(2885..3469)
                     /gene="rnt"
                     /locus_tag="A7326_RS06950"
                     /old_locus_tag="A7326_06905"
     CDS             complement(2885..3469)
                     /GO_function="GO:0016896 - RNA exonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA]"
                     /GO_process="GO:0006364 - rRNA processing [Evidence IEA]"
                     /GO_process="GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rnt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408782.1"
                     /locus_tag="A7326_RS06950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_06905"
                     /product="ribonuclease T"
                     /protein_id="WP_005408782.1"
                     /transl_table=11
                     /translation="MSQRFRGFLPVVVDVETGGFDSQRNALLEIAAVPIEMDENGLLYP
                     GQTASAHVVPAEGLEIDPKSLEVTGIILDHPFRLAKEEKAALDHIFTPVRAAMKKYGCQ
                     RAILVGHNAHFDLGFVNAAVARTGHKRNPFHPFSVFDTVTLAGIAYGQTVLARAATAAG
                     LGWDANEAHSAVYDTEQTARLFCTIANAWPR"
     gene            complement(3705..4226)
                     /locus_tag="A7326_RS06955"
                     /old_locus_tag="A7326_06910"
     CDS             complement(3705..4226)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014036543.1"
                     /locus_tag="A7326_RS06955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_06910"
                     /product="DoxX family protein"
                     /protein_id="WP_088025448.1"
                     /transl_table=11
                     /translation="MNLPTLAAARGQLDRLAPWLAPLGLRLLLAWEYFESGREKLHGQN
                     WFADLQDAFPFPFDQLPATLNWQLATWFELIGAVCLLVGFGTRFAAASLLVLTIVATYA
                     VHWPMEWNSLADLAMGYAISDQGFGNFKLPVLFMAMLLPLIFTGAGKLSLDAWLARWSP
                     SATPARPAVR"
     gene            complement(4253..5008)
                     /locus_tag="A7326_RS06960"
                     /old_locus_tag="A7326_06915"
     CDS             complement(4253..5008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019336968.1"
                     /locus_tag="A7326_RS06960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_06915"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_088025449.1"
                     /transl_table=11
                     /translation="MADTSHTLRAQQHAFTAHLRDPQGVPPPAGLEPRRVAVYQRLLFN
                     NLLGLLSNGFPVCVRLLGEPAWSPLVRRYFATHRCQTPLFTELAAEFVQWLQAQAQLPH
                     PALAELAHYEWVETALYQLAAEPLPPAGDIDPLQVPLRRSPLAWPLLYQWPVHRLGAED
                     APSQPPAEPTGLLVRREADGEVRFAVLSPLAVYLLSSIGEHPGLDGHAYLQHLAAAHGL
                     AEDALAGPGAALLQQFLQAGVIGPLAVPG"
     gene            complement(5001..5876)
                     /locus_tag="A7326_RS06965"
                     /old_locus_tag="A7326_06920"
     CDS             complement(5001..5876)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014036545.1"
                     /locus_tag="A7326_RS06965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_06920"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_088025450.1"
                     /sec_met_domain="DUF692 (E-value: 2.6e-116, bitscore:
                     385.5, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSTDVRASAVHLRSPLRAAAAGLGLRRALLQDLRDAPAGDFDFL
                     ECAPENWIHVGGPAGDALAELAQRHPLSCHGLSLSLGGSAPLDTQLLEQVGQFLDTHRV
                     PLYSEHLSYCSDDGHLYDLLPIPFTDEAVRHTAARIARVQDILGRRIAVENVSYYLAPE
                     PAMDELAFTNAVLAEADCDLLLDVNNVYVNACNHGYDADTFIAGLPAERIVCLHVAGHL
                     DEAPDLKIDTHGSAVIDPVWDLLARTYARIGPRPTLLERDFNFPPYAELQGELQTIRRL
                     QAPHTGIAHG"
     gene            complement(5863..6219)
                     /locus_tag="A7326_RS06970"
                     /old_locus_tag="A7326_06925"
     CDS             complement(5863..6219)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646537.1"
                     /locus_tag="A7326_RS06970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_06925"
                     /product="hypothetical protein"
                     /protein_id="WP_088025452.1"
                     /transl_table=11
                     /translation="MSSSNKTLSLLTATALAAGLGMTASASALSMSDLAQGYLVAGQAA
                     KASTDAKAADAKMAADATKHAEGKCGADGKSAEGKCGADKGKAAGAAAGAKAKTGDKKS
                     AEGKCGEGKCGAKH"
     misc_feature    complement(6332..6347)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     misc_feature    6338..6351
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.13"
                     /tool="antismash"
     gene            complement(6477..7184)
                     /gene="phoU"
                     /locus_tag="A7326_RS06975"
                     /old_locus_tag="A7326_06930"
     CDS             complement(6477..7184)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0051049 - regulation of transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="phoU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265615.1"
                     /locus_tag="A7326_RS06975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_06930"
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="WP_014036547.1"
                     /transl_table=11
                     /translation="MNLPNDHIVKSYDEEQQRLVAEIVRMGEMAVAQLEAAMDVIEKRD
                     ENAAHRIIANDEAIDALEQQISHDVMRLALRGPMARDLREILAGLRIPADIERIGDYAA
                     NVAKRSIALGKVPPLPQIQGLRALGRLAAQQVRRAIAAYRDNDADAALELREDDARLDA
                     QYTALFRELLTYMMEDPRNITPCTHLLFMAKNLERVGDHATNIAENVWFLVHGEQPLPP
                     REKRDETSSTGQP"
     misc_feature    7156..7171
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.64"
                     /tool="antismash"
     gene            complement(7250..8080)
                     /gene="pstB"
                     /locus_tag="A7326_RS06980"
                     /old_locus_tag="A7326_06935"
     CDS             complement(7250..8080)
                     /EC_number="7.3.2.1"
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pstB"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019237787.1"
                     /locus_tag="A7326_RS06980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_06935"
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="WP_005408788.1"
                     /transl_table=11
                     /translation="MNDLSNAVPMQRIAVPSSHESLHTPSPVKLAARGLDFYYDKFHAL
                     KGINLEIPEKRVTALIGPSGCGKSTLLRIFNRIYALYPKLEARGEVLLDGENILSPKYP
                     MNRLRSKVGMVFQKPVPFPMTIFENVAYGIRHHEKLSKADMADRVEQALRQGALWDEVK
                     DKLGQSALGLSGGQQQRLCIARAVALRPSVLLLDEPTSALDPISTSRIEQLVEELKHEY
                     TIVIVTHNMQQAARVSDYTAFMYLGDLIEHDRTEVIFSQPSQRQTEDYITGRFG"
     gene            complement(8100..8963)
                     /gene="pstA"
                     /locus_tag="A7326_RS06985"
                     /old_locus_tag="A7326_06940"
     CDS             complement(8100..8963)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pstA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412770.1"
                     /locus_tag="A7326_RS06985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_06940"
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="WP_088025454.1"
                     /transl_table=11
                     /translation="MSSTADSLYLRRRIGNVVAIAASCATALFGLFFLGWILFTLASKG
                     LAGINWDLFTKMTPPPMQEGGLANAFFGSAVMCALAIGIGTPLGVLAGTWLAEYGNARK
                     AGTVVRFVNDILLSAPSIVLGLFVYTLYVMQTGGNFSAFAGALSLAFIVLPVVVRTTDE
                     MLRLVPSQMREAALSLGIPQWKVIVQVLYRSASAGIITGILLALARISGETAPLLFTAF
                     GNQYWNNNIFQPMASVPVVMNQFAGSPYESWQVLAWAGALVLTVFVLLVSLAARGILLR
                     NRISHD"
     gene            complement(8963..9931)
                     /gene="pstC"
                     /locus_tag="A7326_RS06990"
                     /old_locus_tag="A7326_06945"
     CDS             complement(8963..9931)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pstC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008572163.1"
                     /locus_tag="A7326_RS06990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="A7326_06945"
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="WP_049444211.1"
                     /transl_table=11
                     /translation="MNAIAQPVAAPSTRDTRDARNDKLFRWVLVGTVIFVLIALACAAL
                     SMLWGGRHALQMQGLSFFFSADWNPVENKFGALAPIYGTLVTALIAMVIAVPVSFGIAF
                     FLTEVAPRWLRGPVGTAIELLAGIPSIIYGMWGLFVLVPVMTEYVTPFLNETLGEWPII
                     GPMFQGPPLGIGMLTAGFVLAIMVIPFISSVMREVFLTVPTRLKESAYALGSTKWEVSW
                     DIVLPYTRSAVIGGIFLGLGRALGETMAVAFVIGNSVRLSPSLLEPGTTIAALIANDFG
                     EATETYRSALLLLGFVLFIVTFVVLAIARLMLMRLSRKEGN"
     misc_feature    complement(10399..10412)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    10649..10663
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
ORIGIN
        1 cctgggaagg tctggtgcgt tacaacgggc tggatttcac cgtgttcgac cgcagtaccc
       61 gcccaggcct gcgcgacaac ggcatcggcg cgctgttcgt cgaccgccag ggcgggctgt
      121 ggatcagtga ttcgcgcggc aatgtcagcc atcgtggcaa tgacggccag tggcgggtct
      181 gggagcacca ggccgatacc ccgcaggtgc tgatccagtc catgcagatg gacagccagg
      241 gccgcctgtg gctgctgtat gaaggcaagg gcatcggcta tctgacgccg gacaccggca
      301 tcgtctacca ggctccggcc gctgacctgc cgatggcgat gagcttcacc aagctggtgg
      361 tcgatgcgca ggaccgggtc tgggccggca ccctcgatgg actggtgctg cgcgacaacg
      421 acggcgttct caagcgggcg cctgcggcgt gggggctggg cgccggcagt ggcctgtcgt
      481 ggccgtaccg tgctccggat ggcgcgttgt ggatcgtcgc cggcgagcgc ctgtaccggg
      541 tggaagatga ccagctggtg ttgatgcatc gcctgccggg ccagctgcac atgacctcga
      601 tgctgcagga ccgccacggt gacctgtggc tgggcaccga gaaccagggc ctgctgcgca
      661 tctccgcaca tggcctggag cggctgccgg cgggcctgaa cctgcccggc gggcgcgtgg
      721 tcagcctgcg cgaggacgcc gagggcagca tctgggtggg cgccaacggc ggcctgtacc
      781 gcctgcgcga aacgctgttc agcagttaca ccgagcgcga cggtctcagc ggtgactatg
      841 tgcgcaccgt gttcgaggac cgcgaccgcc agctgtgggt cggcagcgcc agcggcctcg
      901 acctgcagac cgccgatggc cgcttccgcg cgatgccgct gcacaaccgc ggcggcaagg
      961 caccttcggt gctgagcctg gcgcagggcc cggacggtga cctgtgggtt ggaacgttcg
     1021 gcgatggcgt ctaccgtctt ggccgcgatg gccgtctgcg acacaactat gccgccgccg
     1081 atggcatgcc gggcggcaac atccgtgcga tcagcgtgga cccgcagggc gtggtatggg
     1141 ccggcacgca gaagggcgtg gtccgcatcg acggcgaccg cgtgcaggtg tcgagcgttg
     1201 cgggcatgcc cagcggcctg atcaccgcgc ttgaacacga tcaccaaggc aacctgtgga
     1261 ttggcaccat cgagggaatc cgcgtgctgc gcggtgacca cgtgcagtcg atcgacctgg
     1321 cgccgctggg cggcggccgc agtgtgttcg gtttccacca gctgggcgac gcgatgtgga
     1381 tcagcagcga ccgtggcctg taccgctggc gcaacggcac gctggcgcgg gtggggctgg
     1441 agcagggcat gccggtggat gcggtgttcc aactggtgcc ggaccgcctt ggcaatgtgt
     1501 ggatcagcag caaccgcggt gtgctgcgca ctgacatggc caccctcaac gccgtggccg
     1561 atggccgcgc accgcgggtg gtggtggagc gctacaacga gatcgacggc atggccaacg
     1621 cgcaggccaa cggcagctcc gggccatcgg cgatcctgcg ccaggacggc acgttctggg
     1681 tggtcaccgc cggaggcctg agcaccgtcg acccgcaacg cctgcagcgt ttccgtgagc
     1741 gcctttcgcc gccggcagcg attgaaagcg tgcaggtgga tggcgcaccg gtgcattggg
     1801 aaggcccgga ccgcaactac attcccggcg gccgccgctt ggcggtgagc tatgtcggcc
     1861 tgagttacct gatgtctgac cggatccgct accgcacgcg gctggacggc ctggatgcgg
     1921 ggtgggtcga acgcggcccg cagcgcagcg tggagttcgt cggcttgccg ccgggcgact
     1981 acaccctgca cgtggccgct gcccatccgg gtggcagctg gggccagcag gaagcggtat
     2041 ggagcttcac cgtggagccg ttctggtggc agcgacgcag cgtgcaggtg ctgggtggcc
     2101 tgttgctgct ggccgggctg gtggcgctgt accgcctgtt gctgcagcag ctgaaggcca
     2161 gcaacctgcg cctggcacgg cgggtggatg aagccacctt tgacctgcag gccaagaccg
     2221 tgcacctgca ggcgctgaac caggaaaaga ccgaactggc cgagcgtctg gcacgccagg
     2281 ccgaggcctt cgaacggcag gcccgcgagg atgcgctgac cggcctggcc aaccgccgtg
     2341 ccttcgatga gaccctggcg cgcgacttcg cacgttcgca gcgcagtggc catccgctgt
     2401 gcctggtggt gctggatatc gaccacttca aggacgtcaa cgaccgccat agccacagca
     2461 tcggcgatgc cgtgctggtg caggtggcgc ggttgatcgc cgccgccagc cgcgactcgg
     2521 acctgccggc gcggaccggc ggcgaagagt tcgcgctgct gctcaacgac acccgcctgg
     2581 aagaagccgc acagctgtgc gcacgcctgc gcggcctgtt tcacgaccat cccgactggg
     2641 ccggggtgga cggactgcgc gtgaccttca gcgcgggcct ggtggaactg gatgccgacg
     2701 accgcacccc ggcactgctg taccagcgcg cagaccgcgc gttgtatcgc gccaagagcg
     2761 acggccgcga tcgtacgagc attggttgat cgcatccacg catggcgtgg atctaccgtc
     2821 cggtgagtgg tgggtgcgga ccgttggtcc gcactgcgtg gatgcggttg cgccgttggc
     2881 tggcttaccg cggccaggcg ttggcgatgg tgcagaacaa ccgcgcggtc tgttcggtgt
     2941 catacaccgc gctgtgcgct tcattcgcat cccaccccag cccggcggcg gtggctgcac
     3001 gcgccagcac ggtctgcccg taggcgatgc cggccagggt gaccgtgtcg aacacgctga
     3061 acggatggaa cggattgcgc ttgtggccgg tccgcgccac cgccgcattg acgaatccga
     3121 ggtcgaaatg cgcgttgtgg ccgaccagga tcgcgcgctg gcagccgtac ttcttcatcg
     3181 ccgcacgcac cggggtgaag atgtggtcca gcgccgcctt ttcttccttg gccagccgga
     3241 acgggtggtc gaggatgatg ccggtcactt ccagtgattt cggatcgatc tccaggccct
     3301 cggccggcac cacgtgggcg ctggcggtct ggccggggta gagcaggccg ttctcgtcca
     3361 tctcgatcgg cacggcggcg atttccagca gcgcattgcg ctggctgtcg aagccgccgg
     3421 tttccacatc caccaccacc ggcaggaagc cgcggaagcg ttgtgacatc gcgcgctgcg
     3481 cctggggtac tacggaatcg ggagcggcgg caggtgcggg ggtggggtca gtcatgcgtg
     3541 aattctagca gagcgaccct gagcgcccgg ccagcccgtg gcgcacgggt tccctgcgca
     3601 ggagcgtgtc gaccaaggtc gacacccacc ggtgcaccgt gcgctcagga ttccggtagg
     3661 tgccaacctt ggttggcacg gtgcgtgccg accaggggcg gcaactaccg aaccgctggc
     3721 cgcgcaggtg tggccgaggg agaccaccgc gccaaccacg cgtccagact cagcttgccg
     3781 gcgccggtga agatcagcgg cagcagcatc gccatgaaca gcaccggcag cttgaagttg
     3841 ccgaagccct ggtcgctgat cgcatagccc attgccaggt cggccagcga gttccactcc
     3901 atcggccaat gcaccgcata ggtggccaca atggtcagca ccagcaggct ggccgcggca
     3961 aaccgggtgc cgaagccaac cagcaggcag accgcgccga tcagttcgaa ccacgtggcg
     4021 agctgccagt tcagggtggc cggcagctgg tcgaacggga acgggaacgc gtcctgcagg
     4081 tcggcgaacc agttctggcc gtgcagtttc tcgcggccgg attcgaagta ttcccaggcc
     4141 agcagcaggc gcaggccgag cggggccaac cagggggcga gacggtccag ctggccgcgc
     4201 gcggcggcca gggtcggaag gttcatcggt ggttctccgg ggggaagggg cgtcagccag
     4261 ggactgcgag cgggccgatt acgccggcct gcaggaactg ctgcagcagc gcggcaccgg
     4321 gtccggccag cgcatcctcg gccaggccgt gcgcggctgc caggtgctgc aggtaggcat
     4381 gaccatcaag gccggggtgt tccccgatgc tggacagcag gtacaccgcc agcgggctga
     4441 gcacggcaaa gcgcacctcg ccatcggcct cgcggcggac cagcaggccg gtcggttcgg
     4501 ccggcggttg tgacggtgca tcctcggcac cgagccggtg caccggccac tggtacagca
     4561 gcggccacgc cagcggcgag cgccgcagcg gtacctgcag cggatcgatg tctcccgcgg
     4621 gcggcagggg ctcggcggcc agctggtaca gcgcggtttc cacccactcg tagtgggcca
     4681 gttcggccag ggccggatgc ggcagctgcg cctgcgcctg cagccattgc acgaactcgg
     4741 cggccagttc ggtgaacaac ggcgtctggc agcggtgcgt ggcgaagtac cggcgcacca
     4801 gtgggctcca ggccggttct ccgagcaggc gcacacagac cgggaagcca ttgctcaaca
     4861 ggccgagcag attgttgaac agcagccgtt ggtacaccgc cacccggcgt ggctccagcc
     4921 cggccggtgg cggcacgccc tgcggatcgc gcagatgggc agtgaaggcg tgctgctgcg
     4981 cgcgcagggt gtgggaggta tcagccatgg gcgatcccgg tatggggggc ctgcaggcgg
     5041 cggatggtct gcagttcgcc ctgcagttct gcgtagggcg ggaaattgaa atcgcgttcg
     5101 agcagggtgg ggcgcgggcc gatgcgcgcg taggtacgcg ccagcaggtc ccagacggga
     5161 tcgatcaccg cgctgccatg ggtatcgatc ttcaggtccg gtgcctcgtc caggtgcccg
     5221 gccacgtgca ggcagacgat gcgctctgcg ggcagcccgg caatgaaggt gtcggcgtcg
     5281 tagccatggt tgcaggcgtt gacgtagacg ttgttgacgt ccagcagcag atcgcagtcg
     5341 gcttcggcaa gcaccgcatt ggtgaaggcc agttcgtcca tcgccggttc cggtgccagg
     5401 taataggaca cgttctccac tgcgatgcgg cggccgagaa tatcctgcac gcgcgcgatg
     5461 cgggccgcgg tatggcgtac ggcttcgtcg gtgaatggaa tcggcagcag gtcgtacagg
     5521 tggccgtcgt cgctgcagta gctcaggtgc tcgctgtaca gcggcacgcg gtgcgtgtcg
     5581 aggaactggc cgacctgttc cagcagctgc gtatccagcg gcgcgctgcc gcccagcgac
     5641 aatgacaggc cgtggcagct caacggatgg cgctgcgcca gttccgccag tgcatccccg
     5701 gcgggaccac cgacatggat ccagttctcc ggcgcacatt cgaggaaatc gaagtcgccc
     5761 gccggtgcat cgcgcagatc ctgcagcagc gcccggcgca gccccaaccc ggcggccgcc
     5821 gcacgaagcg gcgaccgcag gtggacggca ctggcgcgga cgtcagtgct tggcaccgca
     5881 cttgccttcg ccgcacttgc cctcggccga cttcttgtcg ccggtcttgg ccttggcgcc
     5941 tgccgcagca ccggcggcct tgcccttgtc ggcgccgcac ttgccttcgg cactcttgcc
     6001 gtcggcacca catttgcctt cggcgtgctt ggtcgcgtcc gcggccatct tggcgtccgc
     6061 tgccttggca tcggtgctgg ccttggcggc ctggccagcg accagatagc cctgggccag
     6121 gtcgctcatg ctcagggccg aggcactggc ggtcatgccc aggccggcgg ccagggcggt
     6181 agcagtcagc agggacaggg tcttgttgga actgctcatc ggtggtgctc ctgggtggtg
     6241 tgggcgggtg cccgggtcgc cggcagggtg ccggtggaat cgatggtgca gcgatcctac
     6301 tcaacgaatc ctcgccaaga cctcaaattt tcgtgaggtt tgttacagaa acatccggca
     6361 ggttcgcacc gggcgagccc ggcgcccaca atgcgggtgg aacacgcaaa aaaagaaggc
     6421 cgctgtcacc aggacagcgg ccaccttgga gtcaactccg gtgttgcagt gcagcgtcag
     6481 ggctgcccgg tgctggaggt ctcgtcgcgc ttttcacgcg gcggcagcgg ctgctcaccg
     6541 tgcaccagga accacacgtt ctcggcgatg ttggtggcgt ggtcgcccac gcgctccagg
     6601 ttcttggcca tgaacagcag gtgcgtgcac ggagtgatgt tgcgcggatc ttccatcatg
     6661 taggtcagca gttcgcggaa cagcgcggtg tactgcgcgt ccaggcgggc gtcatcctcg
     6721 cgcagttcca gcgcagcatc ggcgtcgttg tcgcggtagg cggcaatggc acggcgcacc
     6781 tgctgcgcgg ccaggcggcc cagcgcacgc aggccctgga tctgcggcag cggcggcacc
     6841 ttgcccagcg cgatcgagcg cttggcgacg ttggcagcgt agtcgccgat gcgctcgatg
     6901 tcggccggga tgcgcaggcc cgccaggatc tcgcgcaggt cgcgcgccat cgggccacgc
     6961 agtgccaggc gcatcacgtc gtggctgatc tgctgctcaa gcgcatcgat cgcttcgtcg
     7021 ttggcgatga tgcgatgggc agcgttctcg tcgcgcttct cgatcacgtc catcgccgct
     7081 tcgagctggg cgacggccat ttcgcccatg cgcacgattt cggccaccag gcgctgctgc
     7141 tcttcgtcgt agctcttgac gatgtggtcg ttgggaagat tcatggtctg caatccgggt
     7201 agagccaggc catgcctggc tgggacatgt ggcgaaggaa cagcgttgat cagccgaagc
     7261 gaccggtgat gtaatcctcg gtctgccgct gcgacggctg cgagaagatc acttcggtgc
     7321 ggtcgtgctc gatcaggtcg cccaggtaca tgaaggcggt gtagtcggac acgcgcgcgg
     7381 cctgctgcat gttgtgggtg acgatcacga tcgtgtactc gtgcttgagc tcttccacca
     7441 gctgctcgat gcggctggtc gagatcgggt ccagcgccga ggtcggctcg tccagcagca
     7501 gcaccgacgg gcgcagggcc acggcacggg cgatgcacag acgctgctgc tgaccaccgg
     7561 acaggcccag tgcgctctgc cccagcttgt ccttcacttc gtcccacagt gcgccctggc
     7621 gcagtgcctg ctcgacgcgg tcggccatgt cggccttgct cagcttctcg tggtggcgga
     7681 tgccgtacgc cacgttctcg aagatggtca tcgggaacgg caccggcttc tggaacacca
     7741 tgccgacctt gctgcgcagg cggttcatcg ggtacttcgg cgacaggatg ttctcgccgt
     7801 ccagcagtac ttcaccgcgc gcttccagct tcgggtacag cgcgtagatg cggttgaaga
     7861 tgcgcagcag cgtggacttg ccgcaaccgg agggaccgat cagcgcggtc acgcgctttt
     7921 ccggaatctc caggttgatg cccttcaggg cgtggaactt gtcgtagtag aagtccagtc
     7981 cacgcgcagc cagcttcacc ggcgacggcg tgtgcaggct ctcgtgcgag gacggcacgg
     8041 cgatgcgctg catcggcacg gcgttggaaa ggtcgttcat ggcgttatcc acggaaaggt
     8101 cagtcatggg agatacggtt gcgcagcagg atgccgcggg cggcaaggct gaccagcaac
     8161 acgaagacag tcagcaccag ggcaccggcc caggccagca cctgccagga ttcatacggg
     8221 ctgccggcga actggttcat caccaccggc accgaggcca tcggctggaa gatgttgttg
     8281 ttccagtact ggttgccgaa ggcagtgaac agcagcggtg cggtctcgcc ggagatgcgg
     8341 gccagcgcca gcaggatgcc ggtgatgatg ccggccgagg cactgcggta cagcacctgc
     8401 acgatcacct tccactgcgg gatgcccagc gacagggccg cttcgcgcat ctgcgaaggc
     8461 accaggcgca gcatctcgtc ggtggtgcgc accaccaccg gcagcacgat gaaggccagc
     8521 gacagcgcac cggcgaatgc cgagaagttg ccgccggtct gcatcacgta cagggtgtag
     8581 acgaacaggc caagcacgat ggacggtgcc gacagcagga tgtcgttgac gaagcggacc
     8641 acggtgccgg ccttgcgggc gttgccgtac tcagccagcc aggtgccggc cagcacgccc
     8701 agcggggtgc cgatgccgat cgccagcgca cacatcaccg cgctgccgaa gaaggcgttg
     8761 gcgaggccgc cttcctgcat cggcggcggc gtcatcttgg tgaacagatc ccagttgatg
     8821 ccggccaggc ccttggaagc cagggtgaac aggatccagc ccaggaagaa caggccgaac
     8881 agggcggtgg cgcacgacgc ggcgatggcg acgacattgc cgatgcggcg gcgcaggtac
     8941 agcgaatcag cggtgctgga catcagttgc cctccttgcg ggacaggcgc atcagcatca
     9001 ggcgggcgat ggccagcacc acgaaggtga cgatgaagag gacgaagccg agcagcagca
     9061 gggccgagcg ataggtttca gtggcttcgc cgaaatcgtt ggcgatcagc gcggcgatgg
     9121 tggtgcccgg ttccagcagc gacggcgaca ggcgcacgct gttgccgatc acgaaggcca
     9181 ccgccatcgt ctcgccaagg gcgcggccga ggccgaggaa gatgccaccg atcaccgccg
     9241 agcgggtgta gggcaggacg atgtcccagc tcacttccca cttggtggaa cccagcgcgt
     9301 aggccgattc cttcagacgg gtcggcacgg tcaggaacac ttcgcgcatc accgaggaga
     9361 tgaacggaat gaccatgatg gccagtacga aaccggcggt gagcataccg atgcccagcg
     9421 gcgggccctg gaacatcggg ccgatgatcg gccattcgcc cagggtctcg ttgaggaacg
     9481 gggtgacgta ctcggtcatc accggcacca gcacgaacag gccccacatg ccgtagatga
     9541 tcgaggggat gccggccagc agttcgatgg cggtgccgac cgggccacgc agccagcgcg
     9601 gggcgacttc ggtgaggaag aaggcgatgc cgaagctgac cggcacggcg atgaccatcg
     9661 cgatgagcgc ggtgaccagg gtgccgtaga tcggggcgag ggcgccgaac ttgttttcga
     9721 ccggattcca gtcggcggag aagaagaagc tcaggccctg catctgcagg gcatggcggc
     9781 cgccccacag catcgacagc gcggcgcagg ccagggcgat caggacgaag atgacggtgc
     9841 cgaccagcac ccatcggaac agtttgtcgt tgcgggcatc acgcgtatca cgcgtggacg
     9901 gggcggctac aggctgggcg atggcattca tggggacggc agggccagga aggggcgggg
     9961 cggcacggcg tggaagaggc ggtgcccgcg cggggcgggc accgtcgtgt ccatcacttc
    10021 aggtcggtcg cccagtaggc ctcgatctgc ttgaccagtt cggccggcag cggcacgtag
    10081 tgcagctcgt tggcctgggc ctggccgttc tcgaaggccc acttgaagaa ggccagggtg
    10141 tcctggttgc gcttggcgtc cttcggctgc ttctgcatca gcatgaagtt ggtggcagtg
    10201 atcggccagg cctgctcgcc cggagcgttg gtgatgacca ggttgaagtc cttggcgctg
    10261 gcccagtcgg cgctggcggc tgcagcggcg aaggtttccg cgctcggctc gacccagttg
    10321 ccggccgcgt tctgcatggc ggtgtacggc ataccgttct gcagcgcgta ggccagttcg
    10381 acgtagccga tcgagccctt gatctgcttc acgtaggaag cgacgccttc attgcccttg
    10441 ccaccgacgc cgtccggcca ctgcaccgag gtgccttcgc cgaccttgct cttccactcc
    10501 gggctgacct tggacaggta gttggagaag ttgaaggtgg tgcccgaacc gtccgaacgg
    10561 tggaccaggg tgatcttgcc gtccggcagc ttcacgcccg ggttggcggc gacgatggcc
    10621 gggtcgttcc aggtcttgac cttgcccagg aagatgtcgg ccagcagggc gccgctcagg
    10681 cgcagcttgc cggtttccag gccttcgatg ttgaccaccg gcaccacgcc gccgatggcg
    10741 gacgggaact gggccaggcc ggcctgggcc agctcttcgc tgctcagcgg cttgtcggag
    10801 gagccgaagt cgacggtgcc ggccttgatc tgggcgatac cgccaccgga gccgatcgac
    10861 tggtagttga tcttgg
//
