LOCUS       NZ_CP021121            22652 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Streptomyces marincola strain SCSIO 03032 chromosome, complete
            genome.
ACCESSION   NZ_CP021121
VERSION     NZ_CP021121.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6287975)
  AUTHORS   Ma,L., Zhu,Y., Zhang,W., Zhang,G., Tian,X., Zhang,S. and Zhang,C.
  TITLE     Complete genome sequence of Streptomyces sp. SCSIO 03032 revealed
            the diverse biosynthetic pathways for its bioactive secondary
            metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6287975)
  AUTHORS   Ma,L., Zhu,Y., Zhang,W., Zhang,G., Tian,X., Zhang,S. and Zhang,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2017) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            164 West Xingang Rd., Guangzhou, Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method :: Hierarchical Genome Assembly Process v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 165.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002128305.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 06:55:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,513
            CDSs (total)                      :: 5,438
            Genes (coding)                    :: 5,343
            CDSs (with protein)               :: 5,343
            Genes (RNA)                       :: 75
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 19 of 95
            Pseudo Genes (incomplete)         :: 88 of 95
            Pseudo Genes (internal stop)      :: 2 of 95
            Pseudo Genes (multiple problems)  :: 13 of 95
            CRISPR Arrays                     :: 12
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4839974
            Orig. end                         :: 4862626
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021121.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Key Laboratory of Tropical
            Marine Bio-resources and Ecology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22652
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="23"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22652
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22652
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12652](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12652
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(646..1335)
                     /locus_tag="CAG99_RS21150"
                     /old_locus_tag="CAG99_21160"
     CDS             complement(646..1335)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512427.1"
                     /locus_tag="CAG99_RS21150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21160"
                     /product="hypothetical protein"
                     /protein_id="WP_255308253.1"
                     /transl_table=11
                     /translation="MPLPAWNDPELKAGTMIRGALWLVQVIGEGNTFTKEQLREAFPGV
                     SQADRRLRDLRDFGWVILTSTEDATLLAEDQRFVKAGVPVWDTAARRAAAPQKSVTAKE
                     KRSVFARDDYMCTICGISGGESYLDDSNQTAVLSATRRATVLPSGEEEVLLVTECKRCQ
                     AGGDGTPARADEVLKDIGALDASERRRLARWIERGRRGSTPLDRAWSAYRRLPAAARDE
                     VRSALER"
     misc_feature    complement(1412..1425)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.87"
                     /tool="antismash"
     gene            1454..2860
                     /locus_tag="CAG99_RS21155"
                     /old_locus_tag="CAG99_21165"
     CDS             1454..2860
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CAG99_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CAG99_21165"
                     /product="hypothetical protein"
                     /protein_id="WP_086162396.1"
                     /transl_table=11
                     /translation="MAATFGVPPEGEKIRSLVEERLKQAMAEDGAKVTVDWRGEQKHLY
                     VISMPVDMLYFNPDTHRIRAQRTLEPDSNRILEEEPWSEAAQEYLRRLLSCKPSNPSQT
                     DPDFIALQDELDDFGQKEPGIISPHGILVDGNTRCAAMRDLGIKDIRVGVLPADTSRRD
                     INSVELSLQLRRDKRREYSYINRLIAIEDELADGRREEDVARDFNIKVRTLGQDRWVHQ
                     LIKEAIERSSSGEGVRLRLVDFEDHQEKLRELHRDYTTLAKTDPDAAEQLKESRLAMVV
                     LNYPKTSVRLAEADFHNRYLDERLPEELRPVVQESAAVAIPGLDVAVPDAAAAVKTTRA
                     LTDALLQAKAASQAGGKLGTAEVAEADRLIKVARKTFDVAVKMAGQNAQLQKRQIAVPE
                     RLTDAADHVNQCAAEFADAKSKRALDEDAFDDALLTLRTSLVRLAKQAGRTFDSPGDGV
                     AWLLGATREG"
     gene            2860..4692
                     /locus_tag="CAG99_RS21160"
                     /old_locus_tag="CAG99_21170"
     CDS             2860..4692
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155023.1"
                     /locus_tag="CAG99_RS21160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21170"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_086160850.1"
                     /transl_table=11
                     /translation="MAAGAAGPSLAIEFGDSVKKARLRAGSGYEDALRRLALKFASSVQ
                     RSPGTVEIEIDELLTNLVVLASWPQAGSVAWDPQLAALATDSARDAQAVADRLDPAADC
                     AAEMDPAQIDSVLGPAWVADLTSFQRRDIAKLLSMRHGANFSVPGAGKTRVGLAVFHAL
                     RRSKGIERLLIVGPKSCYESWQEENQKCLDEPLSMDVFSRNADPAADSLIVNYERLDGA
                     ANELGQWLAARPSMLLLDEAHRMKLGARGTYGAACLALGPRARHRLILSGTPAPNGVKD
                     LENLFGFVWPGHGRQKVVRAVAGGDLAKASQVLRPLFTRTTKGELGLPPVTTTLRPVPM
                     PPLHQEVYEALIGRFSARAAGHEGDFQTLGRIIVYMLMAATSPALLSVGTTRHEPLAYR
                     VPPLSVPEGTPLFSLMQDLPSYEMSPKYQEVLAIVAENAARGRKTLVWSTFIRSLNTLE
                     RVLGEFSPAVVHGGTGDREAQIERFRADPDCMVLLSNPATLGEGISLHHQCHDAVYVDR
                     DFAAGRFLQSLDRIHRLGLAPGTETRITVLSSVGTIDEVVEQRLSEKLQFMGRILDDPA
                     VQQLADLEEEDPVGGGLDLKDLQALMGHLRARAA"
     gene            4754..5533
                     /locus_tag="CAG99_RS21165"
                     /old_locus_tag="CAG99_21175"
     CDS             4754..5533
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024420.4"
                     /locus_tag="CAG99_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21175"
                     /product="DUF3883 domain-containing protein"
                     /protein_id="WP_159029924.1"
                     /transl_table=11
                     /translation="MRALFTAHSDYSDITPTQYDAAYAWLCETGLLEDLHSSVPAHRRV
                     LDAAIAHSRAPWLSDADLLVRGPGELPDDVLRAAEALGLSDSEAYAQLAAVWGKADAGE
                     RARIGAAGELALVDLLTASTEARVEHVAAWSDGYGYDVSVHAPRHRAHLEVKTTLRRSR
                     LTVYVSRNEYETMLRDPDWELVAVRLTADLELQAVATVPRDWIAAQAPADRSGRGRWES
                     CRFDVPPDVPVPGVSRITPALAEGASRLLSGAAGWPG"
     gene            complement(5579..7585)
                     /locus_tag="CAG99_RS21170"
                     /old_locus_tag="CAG99_21180"
     CDS             complement(5579..7585)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015210.4"
                     /locus_tag="CAG99_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21180"
                     /product="DUF262 domain-containing protein"
                     /protein_id="WP_086160852.1"
                     /transl_table=11
                     /translation="MAVERTNRDVRTLITQIAGGEIMLPEIQRGYMWKASQVARLVESL
                     YRGYPAGSLLFWKTGQLAETREAAIGAPQALPSVMPLYLLDGQQRLTSLYRVLTDHPEA
                     QVVFNVETEVFQNQSAATRRDKKWIKVYDVVGEGADVFAVHSALKAAGLGIPDAEIGRR
                     LNALQKITQRDFHMEVLHDFEYGEVAEIFVRVNSGGRALKTTDLALATLSARSPGFLGR
                     LEAESARWAERGYALDVNFLIKALTLSLSISGKRSSSVARLTAASKESVEAGWEKVRRG
                     LTRVVPLLQEKLLIPTTALIPSLAALHPLVVYYGRRPEGADVPPDVEDGMLYWFMAATA
                     RSRYGGVTDTLVTQDIRALDAEDPVRALLANLGIRDRGITVSADDLAGRNHQSPYLMFC
                     YLAAAHARASDWWDGSPVSAAADGSGKPQHSLVHPASTLRGHRNKYSTAEINELANIVF
                     VSQETAKNIIGNRSPEAYLRDLLASDLAAHSVPEAREVLSAARYRDFLSARRALLAARI
                     TALLNGFRPAFLTRGAPRAADASSDRSLTLSGYSTGGRAVLAARAEAAGRSWVCCIDAA
                     EIDAALDAAAVGLASDVRVGGDTVPMRVDDEGGVTLVLGPFLVRGSLDQWHSAAKDAFD
                     DAQPLTACPEPTDEQWPGEPAEFLLSEAAVRGT"
     misc_feature    7768..7782
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     gene            complement(7792..8277)
                     /locus_tag="CAG99_RS21175"
                     /old_locus_tag="CAG99_21185"
     CDS             complement(7792..8277)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010064799.1"
                     /locus_tag="CAG99_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21185"
                     /product="very short patch repair endonuclease"
                     /protein_id="WP_086160853.1"
                     /transl_table=11
                     /translation="MTKQPPQRDPAPWAPPAGSWASSAANRRSMLGNRNRDTSPERALR
                     SLVHAAGLRYRVAAKPLPGMRRTADMVFRPVRVAVFVDGCFWHGCPGHFVPPKTNPDYW
                     RDKIGRNVQRDRDTDARLAEAGWLVLRFWEHEPVEACSRAVCDAVASRRVALANSRS"
     misc_feature    8341..8356
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.18"
                     /tool="antismash"
     tRNA            8677..8750
                     /anticodon=(pos:4848685..4848687,aa:Met,seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CAG99_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="CAG99_21190"
                     /product="tRNA-Met"
     gene            8677..8750
                     /locus_tag="CAG99_RS21180"
                     /old_locus_tag="CAG99_21190"
     misc_feature    complement(8804..8818)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     gene            9100..9900
                     /locus_tag="CAG99_RS21185"
                     /old_locus_tag="CAG99_21195"
     CDS             9100..9900
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433074.1"
                     /locus_tag="CAG99_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21195"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_255308255.1"
                     /transl_table=11
                     /translation="MNGESPVVPRTDRPHSARMYDYLLGGRDYYAADSKAAENALAAAP
                     TLRIAAQENRKFIARAVRHLVLDVGIRQFIDLGPGLPTTENVHQVAQEADPEARVVYVD
                     NDPIVLAFGGAMLEQNERTTVVHGDIRDPLAVLHHPRTREQIDPDEPVGVLAVAVLHFI
                     RDEDDPAGIVRALADVLAPGSHFVLSHGTADISPQAAMGVQAAYRSHGVPLTLRSKERF
                     GEFFTGLELIEPGIQIVSEWRATEPEAERPSCEDVSWYGGVGRL"
     gene            10001..12652
                     /gene="lanKC"
                     /locus_tag="CAG99_RS21190"
                     /old_locus_tag="CAG99_21200"
     CDS             10001..12652
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998777.1"
                     /locus_tag="CAG99_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21200"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_086160855.1"
                     /sec_met_domain="micKC (E-value: 6.7e-232, bitscore: 770.3,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 4.8e-09, bitscore: 34.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 0.00051, bitscore:
                     17.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVFCLVDRHFYEAPERAASRDGAGGGQEGLYETARRPVPQ
                     GWLSERFGDWLHLQPRDGITPPQGWKIHVSACLDNADKTAAKVWDYCVPRRIPFKFVPS
                     AQLLFLRNSKYAGRHSSGKFVTIYPADEDALRTVLTDLGDQLAGEPGPYILTDLRWERG
                     PLYVRYGGFVPRYCDDGTGAVVPAIENAEGRLVPDRRGPAFGVPAWVTLPPFLAPHLAA
                     RNEVTVAALPYRIDSALHFSNGGGVYRGTDTRTGDAVVLKEARPHAGLAADGADAVTRL
                     EREKAALDRLAGLEVAPGVRDWLTVGEHRFLVMDHVPGRTLNAFFAERHPLLATDPAPD
                     AVASYTRWALAVHRGVERAVAALHGRGLVFNDLHMYNIMVAPDETSVTLLDFEAAAPAE
                     EGARQVVAHPGFIAPADRTGFAVDRYALACLRLALFLPMTTLFAVDRDKAAHLARVARR
                     EFPDVPAAFFDEAVAEIEGRQDRNARKRPAAPPEPGDWPAARASMARAILASATPERED
                     RLYPGDIAQFGPGGGLGLAHGAAGVLYALAETGAPRHPEGERWLLRRAADPPRNTPLGL
                     YDGLFGVVHVLHRLGHTEAALDLATRALGEGWERLPAHLHGGLAGIGLVLDDLAADTGN
                     PALAVHAGRAAELAARHVAGPAEPRGHRRAGLLHGATGVALLFLRRYERTGETRLLATA
                     AAALRRDLAHCRADRSGALLVDEGDRLMPYLGEGSVGIAAVLDDYLAAASSAGLPAEDD
                     LTRAAADILPAARLRYYAQPGLFRGRAGMIWHLARTAARPAPPGPRPGPEPEAALAAQI
                     DALGWYAMAYDGELAFPGEQMMRLSMDLGTGTAGCLLALGTALHRPGDPAGLPRLPFLP
                     HPRHPKARPPSA"
     misc_feature    complement(12705..12719)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.04"
                     /tool="antismash"
     misc_feature    12722..12732
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            12726..12857
                     /locus_tag="CAG99_RS21195"
                     /old_locus_tag="CAG99_21205"
     CDS             12726..12857
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471140.1"
                     /locus_tag="CAG99_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21205"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_086160856.1"
                     /transl_table=11
                     /translation="MSLLDLQSMEPEVASGGGGEGDLSSLSLLICDTHSSNSVILCL"
     CDS_motif       12726..12785
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSLLDLQSMEPEVASGGGGE"
                     /locus_tag="CAG99_RS21195_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12786..12857
                     /prepeptide="core"
                     /locus_tag="CAG99_RS21195_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="15.70"
                     /molecular_weight="2264.6"
                     /monoisotopic_mass="2263.2"
                     /core_sequence="GDLSSLSLLICDTHSSNSVILCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSLLDLQSMEPEVASGGGGE"
                     /leader_location="[12725:12785](+)"
                     /alternative_weights="2282.6"
                     /alternative_weights="2300.6"
                     /alternative_weights="2318.6"
                     /alternative_weights="2336.7"
                     /alternative_weights="2354.7"
     gene            12949..14721
                     /locus_tag="CAG99_RS21200"
                     /old_locus_tag="CAG99_21210"
     CDS             12949..14721
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983509.1"
                     /locus_tag="CAG99_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21210"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_086160857.1"
                     /transl_table=11
                     /translation="MPTHPLDPTLRATARQGAGRMAALFALSLAAAGVALALPTALGRA
                     LDALLAEGDATRGPALLTAGLVIAQILVGVLTTVLTAGADAHGAAWLRGRLLRHLLAVG
                     PGAASRFPEGDLVTRATGNAVHAGAAPAALAAAFAAAATPLGAIVALAVTDARLALVFL
                     AGLPLLALLLRAFARSAGDAFAGYQRAQADIAGRLVDALRGARTIAAAGTEEAERRRVL
                     DPLPRLGAHGLRMWRVNARATGRAAALTPLLQLAVVATGGLLLAAGDLTVGGLLAAARY
                     AALAGGVGLFVGHLNRLVRARAAAVRVGEALAVPPPRHGGAALPPGGPGRVEFRGVSAR
                     RGGREVLRGLDLVVPGGSTVALVGRSGAGKSLLAALAGGLAEPDAGRVLIDGVPVTDLA
                     PDALRAEVGYAFERPALLGGTLAPTVAATIGLGPGPAPPPERVAAAARAARADGFIRTL
                     PDGYATRCDGVPLSGGELQRLGLARAFARGGRLLILDDATSSLDTVTELHVARALAAHA
                     AARTRLVVAHRAGSAARADLVAWLDDGRVRALAPHGQLWARADYRALWAADEPAPAARG
                     AAAGADGAGGAAGA"
     gene            14714..16618
                     /locus_tag="CAG99_RS21205"
                     /old_locus_tag="CAG99_21215"
     CDS             14714..16618
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655806.1"
                     /locus_tag="CAG99_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21215"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_255308256.1"
                     /transl_table=11
                     /translation="MRDHAVFRYLRRNRRPLAVLAAWGLLPAAQTFLLGYGLARALDDG
                     FLAGRTGVGLAWLAAAGGGVLAGAFGTTRVHRAVGALAEPLRDGLVREVVARGLHRAVR
                     AGRPESGTADVSRLTHQVEIARDSFAGLVLVLQMFVCTLAGSLAGLASLAPVLLPVVLG
                     PLLLALALFAWSLRPLARRQRAVLVADEALADAFGETAGGLRDITAAGVRGRAEAAVGA
                     RVDAELAAALALGRWGAVRVVALGLGGQLPILLLLFLGPWLLRNGVTPGGLLGALTFVT
                     QALLPALQALLGGVGSAGTRLAVVIARLRTDPLPPQGPPAEPARERAGAAVEPSGAAPA
                     ERAGPAPAREAPAPGARAARRRPAVELRGVTFAYGGRAEPVLDGLDLAVPPGGHLAVVG
                     PSGAGKSTLAALAAGLLAPRAGRVALCGRPVAGRTAAELAALRVLIPQEAYVFRGSVAD
                     NLSYLRAAPLPAAALTAAAEAVGAGDLVDRLGGPAGQVDPAALSAGERQLLALTRAFLS
                     PAPVALLDEATCHLDPAAEAGAERAFAARPGGTLVVIAHRISSARRADRVLVLDGAEAH
                     SGTPSELLGRSALFRDLAAGWSDPSRAPGDADGVDAVAGPGLADDGGQVVAHRALREP"
     gene            complement(16505..17107)
                     /locus_tag="CAG99_RS21210"
                     /old_locus_tag="CAG99_21220"
     CDS             complement(16505..17107)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="CAG99_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21220"
                     /product="response regulator transcription factor"
                     /protein_id="WP_107485900.1"
                     /transl_table=11
                     /translation="MIRLLFVHDDTLLRCGLTSLLGAEVDIEISSLSWEALTRAEPPPP
                     GTVRLADVTCPGFARYADETVRQTGAEDEHGLVVLAPAGRPGLLTRAFEARALGYVSKE
                     APPERLLDAIRAVAKGGRYVDDALAYDFLSASRMPLTPRELRVLALAADGAPVPEIAGE
                     LWLAEGTVRNYLAAVIRKTGARNRVDAIRIARSAGWV"
     misc_feature    complement(16616..16618)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17096..17098)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    17244..17259
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.5"
                     /tool="antismash"
     misc_feature    complement(17320..17334)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.83"
                     /tool="antismash"
     misc_feature    17331..17340
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.14"
                     /tool="antismash"
     misc_feature    complement(17405..17418)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    17424..17439
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.4"
                     /tool="antismash"
     gene            complement(17512..18171)
                     /locus_tag="CAG99_RS21215"
                     /old_locus_tag="CAG99_21225"
     CDS             complement(17512..18171)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433073.1"
                     /locus_tag="CAG99_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21225"
                     /product="DedA family protein"
                     /protein_id="WP_086160859.1"
                     /transl_table=11
                     /translation="MQETLGILLYAPWIYVIVAVSILLDVFVPFLPSGVLVVTAATAAA
                     GTAADVAGLPTPGPDQALPHLFLLVLCATTASVVGDLLAHRLALRGGRRFDSAIARSRR
                     LDAAQQRLATALRGRRGGPLVVLARFAPAGRAVVSMGAGVARRRTREYLPWSALAAVVW
                     TGYSVGVGYLGGHLLGVSWLSTGLSLIALIGAGFVAARLLRLSPTAEPPAAVPQAP"
     misc_feature    18204..18219
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.86"
                     /tool="antismash"
     misc_feature    complement(18363..18378)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.81"
                     /tool="antismash"
     gene            18370..18939
                     /locus_tag="CAG99_RS21220"
                     /old_locus_tag="CAG99_21230"
     CDS             18370..18939
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018530858.1"
                     /locus_tag="CAG99_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21230"
                     /product="superoxide dismutase family protein"
                     /protein_id="WP_086160860.1"
                     /transl_table=11
                     /translation="MKILATGAVAMTAVLATAGSSVAAGQDDILLYDAGRFVPLGEGTG
                     VVPKAVTYNEELVPPGSQIHVAQGIRGNSMLIDIATLGLDPGHTYGTHVHTEPCGADPA
                     DAGGHYQDQQGVVDEDSEVWLDFTVDERGVGQAEVYKNWLFRAGEAGSLVLHERGTSEG
                     HDEHPPGDAGARVACFSIPFAGVPAA"
     gene            complement(19064..19753)
                     /locus_tag="CAG99_RS21225"
                     /old_locus_tag="CAG99_21235"
     CDS             complement(19064..19753)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433070.1"
                     /locus_tag="CAG99_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21235"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_086160861.1"
                     /sec_met_domain="HAD_2 (E-value: 1.3e-20, bitscore: 72.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPLTLTARALLLDMDGTLVNSDAAVERVWRTWAEMRDVDPVRVF
                     AIMHGRQARATMADLLPERSVEEHEADAAWLLARETADTEGVVPIPGAGAFLDAIEHAP
                     HALVTSADSGLARARMSAAGLRMPEVRITAESVSASKPDPEGFLKGAAELGIAPADCLV
                     FEDSAAGIEAARAAGMRVIGVGPRAAALAPTAYAATLENVRVEAAPRPRPEGFPPSDGL
                     IRLTVRP"
     misc_feature    complement(19885..19903)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.75"
                     /tool="antismash"
     gene            20281..21237
                     /locus_tag="CAG99_RS21230"
                     /old_locus_tag="CAG99_21240"
     CDS             20281..21237
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013625.4"
                     /locus_tag="CAG99_RS21230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21240"
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_107485903.1"
                     /transl_table=11
                     /translation="MTIDRSECLICGRPVPPTGEPDCECWTHSLSRPVEPPLHGPDPAD
                     VALFPVDASAPGQRQAPAGVPRAARAPASRPAPPVPQRPTGTHRKPRGRTRIATAAGGA
                     VAAVVGCTALAASILSGQGRQEQAHEPDGAGPSLAQPDGGDARPDPPSPPAPDREGADA
                     APGPGPADPERPEPDGGDGTAGSERPESPTPDEEPSEPPADDRPEPDPVDPEPTPDAPP
                     VPGPETPATPEPPTPSEPSEGAAPVLGAGDEGPEVAELQRRLLQLNWVYRGQAHGRYDE
                     QTAAAVARFQVAYGVRGDPEGLYGPQTRRALEQHTRP"
     gene            complement(21248..22138)
                     /locus_tag="CAG99_RS21235"
                     /old_locus_tag="CAG99_21245"
     CDS             complement(21248..22138)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010637596.1"
                     /locus_tag="CAG99_RS21235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_21245"
                     /product="ECF transporter S component"
                     /protein_id="WP_255308257.1"
                     /transl_table=11
                     /translation="MRLGPRSAAALVLVSAAGVVAFGWPLLADSASGLAHSADAPWLFA
                     LLLPLLLAVVVATIADTGLDAKAVAMLGVLAAAGAALRPLGAGTAGLQPMFFLMVLSGR
                     VLGPGFGFVLGGVSMFASALLTGGVGPWLPFQMLSMGWLTMGAGLLPGAHRLRGRAELA
                     LLAGYGALASLAYGLVMNLQGWPYLAGMSSGISFVPGDPLPDNLARYAAYVATTSLGWD
                     VPRALLTVVLILLCGGSVLRALRRATRRAAFEVPARFEAPGPGESTAGDEAASHAGASK
                     HEGAQGPGEAPAHPA"
ORIGIN
        1 cgaggagcag cgccttcggc ttgatcctgc cgcacagttc gacagcccag gcgaacaggt
       61 cccgctcgtc gttggcgccc agctgcttgc ccgcgatact gaaggggggg cacggcactc
      121 caccggcgag caggtcgatg tcgaggtggt cagccggatc ccagactccc gggtcggcga
      181 catcgccgac cttgacggtc tcctcggcgc cgacttgtga gtaaccgaga acggcgtgca
      241 ggttgtggcg cagggtcgtg gcggcgttgc ggtccagctc tactgcgagg cggtggcgga
      301 acccggcccg ttccaagccg agggtctgcc cgccggcgcc agcgcagatc tcgacgacct
      361 cgagttgctc cgatgccgac atgcgatctc cctccgggcg ccgaaaacgc cagtgcgcaa
      421 ccgatcagcg gcacctccgg ccgcgtgcag ccaagacaag cgtccggctg accacaggta
      481 ccgccgtgca cagtcgcagg ttactggggc gtgcggtgca atcggtacgg cgagccggac
      541 atgccagtga agtctaaatg gctccactgg ggcgtccgca ccggccaggg cagagcccag
      601 gttccttgcg gggactcgga cgggcctgca ccgggccgcc gctggtcagc gctccagcgc
      661 cgaccggact tcatcccgcg cagccgccgg caggcgccgg taggcgctcc aagcgcggtc
      721 caggggcgtg gagccgcggc ggccgcgctc gatccagcgg gcgagccgcc ggcgttcgga
      781 ggcgtcgagg gctccgatgt ccttcaggac ctcgtctgcg cgggcggggg ttccgtcgcc
      841 tcctgcctgg cagcgcttgc attcagtgac aagaaggacc tcttcctctc cgctcgggag
      901 aacggtggcg cgccgggtcg cggacagcac ggctgtctgg ttggagtcat ccaagtagga
      961 ctcaccgcca gaaatgccgc atatcgtgca catgtagtcg tcgcgggcga aaactgaccg
     1021 cttctccttg gctgtgacgg acttctgcgg cgccgccgcg cggcgggctg cggtgtccca
     1081 gaccggcacc ccggccttga cgaaccgctg atcctctgca agcagcgtcg cgtcttcagt
     1141 gctggtgagg atgacccatc cgaagtcacg gagatcacgc aggcgccggt cggcctgtga
     1201 gacaccgggg aacgcctcgc ggagctgctc tttcgtgaaa gtgttcccct cgccgatcac
     1261 ctggacgagc cacaaggctc cgcggatcat ggtgccggcc ttcagttccg ggtcgttcca
     1321 ggcgggcagt ggcacttcgg ctccgttcgt cgcgttctgg agcttgattc tggatcagca
     1381 ggtggtctgc tgtcagcggc tcctgtcatg atgcatggac gtccggttgc gatgtcctgc
     1441 taggaggctc ctgttggctg ccacgttcgg tgtcccgcct gagggggaaa agatccgctc
     1501 cctggtggag gagcgcctga agcaagccat ggcggaggac ggggccaagg tcaccgtgga
     1561 ttggcgcggc gagcagaagc acctttatgt gatctccatg ccggtggaca tgctctactt
     1621 caacccggac acgcaccgga tccgcgcgca gcgcaccctg gagccggaca gcaaccgcat
     1681 cctcgaggag gagccgtgga gcgaggcggc gcaggagtac ctccgccgtc tgttgagctg
     1741 caagccgtcg aacccctcgc agacggaccc cgactttatc gccttgcagg atgaactgga
     1801 tgatttcggc cagaaggagc cggggatcat cagccctcac ggcatcctgg tcgacggcaa
     1861 cacccgctgc gcagcgatga gggacctggg aatcaaggac atccgtgtcg gtgtgcttcc
     1921 cgccgacacg tcccgccgcg acatcaacag cgttgagctg tcccttcagc tccggcgcga
     1981 caagcggcgc gagtactcgt acatcaacag gctcatcgcg atcgaggacg agcttgccga
     2041 cggacggcgc gaggaggacg tggcgcgcga cttcaacatc aaggtccgca cactcggcca
     2101 ggaccgctgg gtccaccagc tgatcaaaga ggcgatcgaa cgcagcagtt ccggggaagg
     2161 ggtcagactg cgcctggtgg acttcgaaga ccaccaggag aagcttcgcg agctgcaccg
     2221 cgactacacg acgctggcga agacggatcc ggatgccgcc gagcagctga aggagtcccg
     2281 tcttgcgatg gtcgtgctga actatcccaa gacgtccgtc cgcctcgccg aggccgactt
     2341 ccacaaccgc tacctcgacg agcggctgcc ggaagagctc cgcccggtgg tccaggagtc
     2401 cgctgctgtg gcgattcccg gactggatgt cgccgtgcct gatgccgcag ctgcggtcaa
     2461 gaccacccga gcgctcactg atgccctgct ccaggcgaaa gctgcctcgc aggccggggg
     2521 caagctgggt accgctgaag tcgccgaggc ggaccgcctg atcaaggtgg cgcgcaagac
     2581 gttcgacgtg gcggtgaaga tggccgggca gaacgcgcag ctgcagaagc ggcagatcgc
     2641 cgttcccgag cgcctgacgg acgctgccga ccacgtgaac cagtgcgccg cagagttcgc
     2701 cgacgccaag tccaagcgcg ccttggacga ggacgccttc gatgacgctc tgctcaccct
     2761 ccgcaccagt ctggtccggt tggcgaagca ggcaggccgc acattcgact cccccggcga
     2821 cggtgtcgcc tggctgctcg gcgcgaccag ggaaggctga tggcggcggg ggcggctgga
     2881 ccgagcctgg cgatcgaatt cggcgacagc gtgaagaagg cccggctgag ggccggaagc
     2941 ggctacgagg acgccctccg acggctcgct ctgaagttcg cgagcagcgt gcagaggtcg
     3001 cccggaacgg tcgaaatcga gatcgacgag ctcctgacga acctcgtcgt gctcgcttcc
     3061 tggccccaag cgggcagcgt ggcctgggat ccgcagctgg ccgcgctggc cacggactcg
     3121 gccagagacg ctcaggccgt ggcagaccgc ctcgacccgg cggctgactg cgcagcggag
     3181 atggacccgg cgcagatcga cagtgtgctc ggtccagcct gggtggctga cctgacttcc
     3241 tttcagcgca gggacatcgc caagcttctg tccatgcggc acggtgccaa cttctccgtg
     3301 cccggtgccg ggaagacccg cgtgggcttg gcggtcttcc acgcgcttcg ccggagcaag
     3361 ggcatcgagc ggctgctgat tgtcggcccg aagtcctgct acgaatcctg gcaggaagag
     3421 aaccagaagt gcctggacga gccactgagc atggacgtgt tctcgcgtaa cgccgaccct
     3481 gccgcggact cgctcatcgt gaactacgag cggctcgacg gcgctgcgaa cgagctgggc
     3541 caatggctgg cggcccgccc gtccatgctg ctgctggatg aggcgcaccg catgaagctg
     3601 ggtgcccggg gcacgtatgg tgcagcctgc ctcgccctcg gcccccgggc ccggcaccgg
     3661 ctcatcctgt cgggtactcc ggctccgaac ggcgtcaagg acctggagaa ccttttcggc
     3721 ttcgtctggc ccggccacgg acgtcagaag gtcgtccggg cggtggccgg cggcgacctc
     3781 gcgaaggcga gccaggtctt gcgtcctctg ttcacccgca cgaccaaggg ggaactcggg
     3841 ctgccgccgg tgaccacgac actgcgcccg gtgccgatgc cgcccctgca ccaggaggtg
     3901 tacgaagcgc tcatcggccg cttctcggcc cgcgccgcag gccacgaggg tgacttccag
     3961 actctcggga ggatcatcgt ctacatgctc atggccgcga cgagccctgc cctgctgtct
     4021 gtggggacca cgcggcacga gccgctcgcg taccgggtgc ccccgctctc ggtgccggag
     4081 gggaccccgc tgttcagcct catgcaggac cttcccagct acgagatgtc tccgaagtac
     4141 caggaggtct tggcgatcgt cgcggagaac gccgcccgag gccgcaagac gctcgtctgg
     4201 tctacgttca tccggagcct gaacacgctg gagcgggtac tcggcgagtt ctcgccggct
     4261 gtggtccacg gcgggacagg ggaccgcgag gcccagatcg agcggttccg cgcagatcct
     4321 gactgcatgg tgctgctgtc caaccccgcc actctcggcg agggcatcag cctgcaccac
     4381 cagtgccatg acgccgtcta cgtcgaccgg gacttcgctg cgggacgctt tctccaaagc
     4441 cttgaccgca tccaccgcct cggcctcgct cccggaacgg agacccggat cacggtactg
     4501 tcgtcggtcg gcacgatcga cgaggtcgtt gagcagcggc tgagtgagaa attgcagttc
     4561 atgggccgca ttctcgacga tccggctgtg cagcagctgg cagacctcga ggaggaggac
     4621 ccggtcggcg gcggcctgga cctgaaggac ctccaagcgc tgatggggca cctccgtgcc
     4681 agggccgcct gagcccgtcc tgcgcgcggc ggtccgctgg ctggaaaggc tcgcagtcag
     4741 cggtgccccg cgcgtgcgcg ccctgttcac cgcgcacagc gactacagcg acatcacgcc
     4801 gacccagtac gacgcggcgt acgcatggct ctgtgaaacc gggcttctcg aggatttgca
     4861 cagcagcgtc cccgcgcacc gccgggtctt ggacgctgcc atcgcgcaca gccgtgcgcc
     4921 ctggctctcg gatgcagacc tcctggtccg cggtcccggc gaactgcccg acgatgtcct
     4981 gcgcgcggct gaggccctcg gcctcagtga cagcgaagcg tacgcccagc ttgccgccgt
     5041 ttggggcaag gcggacgcgg gcgagcgcgc gcggatcgga gcagcgggcg agctggccct
     5101 cgtcgatctg ctgaccgcct ccaccgaagc ccgtgtggag cacgtggcgg cctggtcgga
     5161 cggctacggc tacgacgtct cagtccatgc tccacggcac cgcgcgcacc tggaagtcaa
     5221 gaccaccctg cgccgcagcc gtctgacggt gtacgtctct cggaacgagt acgagacgat
     5281 gctccgcgac ccggattggg aactggtagc agtccggctg acggctgatc tggagttgca
     5341 ggcggttgcg acagtgccga gggactggat cgccgcccaa gcccccgctg accggagcgg
     5401 ccgggggcgc tgggagtcgt gccggttcga tgtgccgccc gatgtaccgg tgccgggcgt
     5461 atcccgcatc acccctgcac tggcagaagg cgcatcgaga ctcctcagcg gcgccgctgg
     5521 ctggcccggt tagcgcgagc ggcactgcct gtgcagccgg gccgaccggt ctcggcaatc
     5581 aggtgccgcg gaccgcggcc tccgagagca ggaactccgc aggctcgccc ggccattgct
     5641 cgtcggtggg ttccgggcat gccgtcagag gctgtgcatc gtcgaatgca tccttggctg
     5701 cggaatgcca ttggtcgagg gaaccgcgga caaggaacgg accgaggacg agagtcacgc
     5761 cgccttcgtc atcgacccgc atgggtactg tgtcaccgcc gacacggaca tcgctggcca
     5821 ggccgacagc agcagcgtcc agcgcggcat cgatttcagc agcgtcgata cagcacaccc
     5881 agctccgccc cgcggcttcc gcccgggcgg ccagcacggc ccgtccaccg gttgagtacc
     5941 cgctcagggt cagcgagcgg tccgaggaag cgtctgctgc ccgaggggcg cccctggtga
     6001 gaaaggccgg gcggaagccg ttgagcagcg cagtgatccg tgcagcgagc agcgccctgc
     6061 gggcactgag gaagtcgcgg tatctcgccg cactcaagac ctctcgggcc tcggggacgg
     6121 agtgggcggc aagatcgctc gcaagcaggt cccggaggta tgcctccggt gagcggttcc
     6181 cgatgatgtt cttcgccgtc tcctgcgaga cgaagacgat gttggcgagc tcgttgatct
     6241 cggcagtcga atacttgttg cggtggcccc tgagcgtcga tgcgggatgc accaggctgt
     6301 gctggggctt accggaaccg tcagcagcgg ccgagacggg actgccgtcc caccagtcac
     6361 tcgcccgggc atgtgccgca gccagatagc agaacatgag gtatggactc tggtggttcc
     6421 gccccgcgag atcgtcagcg ctcacggtga tgcctctgtc gcgaataccg agattggcaa
     6481 gcagggcccg caccgggtct tcggcatcga gcgccctgat gtcctgtgtc accaacgtgt
     6541 ccgtcacacc gccgtagcgg ctgcgagccg tggcggccat gaaccagtag agcatcccgt
     6601 cctcgacatc aggaggaacg tctgctccct ccgggcggcg gccgtagtag accaccagag
     6661 ggtgcagggc agccagcgac gggatgagag cggtggtcgg gatgagcagc ttctcctgga
     6721 gcaggggcac gacacgggtg agcccgcggc gcaccttctc ccagccggcc tcgaccgact
     6781 ccttgctcgc cgccgtcagc ctggccacgg acgacgaccg cttgccggag atcgacaggc
     6841 tcagcgtgag ggccttgatg aggaaattga cgtcgagagc gtaaccccgc tcggcccagc
     6901 gagcggactc cgcctccaac cgccccagaa aacccggaga acgggcagac agtgtcgcaa
     6961 gtgcgaggtc tgtcgtcttg agcgcccgcc cgccgctgtt cacccgcacg aagatctctg
     7021 cgacctcccc gtactcgaag tcgtgcagca cctccatgtg gaaatcgcgc tgggtgatct
     7081 tctggagcgc gttgaggcgg cggcctatct cggcgtccgg gatgccgagc ccggctgcct
     7141 tgagcgcgct gtggacagca aacacgtcgg ccccctctcc gacgacgtcg tagaccttga
     7201 tccacttctt gtcgcgccgg gtggccgcgc tctggttctg gaagacctcg gtctcgacgt
     7261 tgaacacgac ctgggcttcc ggatgatcgg tgaggacgcg gtagagcgaa gtgaggcgct
     7321 gctgtccgtc cagcaggtag agcggcatca cgctgggcag ggcctgcggg gcaccgatgg
     7381 cagcctcgcg ggtttcggcg agctggccgg tcttccagaa gaggagggag cccgcaggat
     7441 atccgcggta gagcgactcg acgagcctgg cgacctgcga agctttccac atgtagccgc
     7501 gctggatctc gggaagcatg atctccccgc ctgcgatctg cgtaataagc gtccggacat
     7561 ccctgttcgt acgttcgacc gccatgcctc gaagccccca tactccgcac ggggccgact
     7621 gcccgccgtg actgcttggg taccagcagt gtccgtcttc tattcgagca gcgcgtgccg
     7681 ctgcaccccc tgcgacaggg tagcggaacg ctgaatccgg tgcgtccggg acttccgtgc
     7741 ggatcgccgg gcccggctcc gggccgcatc actgctggcg atcagtcgac gtcaggacct
     7801 gctgttggcc aaagccacgc gccgggacgc gactgcatcg cagacggctc gcgagcatgc
     7861 ctctaccggt tcgtgctccc agaacctcag gacgagccag ccggcttcag cgaggcgggc
     7921 atccgtgtcg cgatcgcgct ggacgttgcg cccgatcttg tcgcgccagt agtcgggatt
     7981 cgttttcggc ggtacgaagt gcccagggca cccgtgccag aagcacccgt ccacgaaaac
     8041 ggcgacgcgt accggacgga acaccatgtc ggcggtgcgc cgcatgcccg gcagcggctt
     8101 ggccgcgacg cggtagcgca ggccggcggc atggacgagc gaccgcaagg cgcgctcggg
     8161 ggaggtatcg cggttgcggt tgccgagcat gcttcggcgg ttcgcagcgg aggacgccca
     8221 ggagcccgct gggggcgccc agggcgcggg gtcccgctga gggggctgct ttgtcatcgc
     8281 tcaaaaagtc taggcccaag cccgaggcgc tttcctgccg ggctgcgatc gccacgtgct
     8341 gagaccgact ggtcctgcgg tgttcggagt gagggaggcg ccccgctcgc acccggccag
     8401 gtcgtattcc tcgcgcaagg tggcgaacgc ggagaccgcc gagcgggccg cgacgcgggc
     8461 cgtctggtcg cgattcgcag ttcggaggac agggtttctg ccgcggtggc gtcgccgtgg
     8521 accagcgggg gagcgtgact cgtcgcggcg cggccggcgg tctcgcgagc gtggcgcacg
     8581 gcggtctccg gctgcccccg tcgcgggggg tgtgccgggg gccggaggtg gtgtggtcgg
     8641 aggggggccg gggatggcgt agagtggtgc acacgacgcg gggtggagca gctcggtagc
     8701 tcgctgggct cataacccag aggtcgcagg ttcaaatcct gtccccgcta cgacagaagg
     8761 ccccggatct tccctggtcc ggggccttcg tgctggggtg aatggggccg ttcggcccac
     8821 gtggggcgag agggccgcgc gctagactgg cgtgacttcc tggaggccgc gacggcgcgg
     8881 cccacgggct cgggcgatcg aggtgccggg agaggagttg atctcccatg ggttctgccc
     8941 gactgccctt cggcggggcc ctcccggtgc cgccggtcga cgggagcgcc gccggttccg
     9001 gccggggcgc ggcgtgggcc gagatcgacg gccgaccgca aatcgcacta ttcttcgagc
     9061 cgttgatccg gcgttcaacc agcatggagg ggcgtgcccg tgaacggtga atcgccggtc
     9121 gttccccgga ccgaccgacc gcattcggcc cggatgtacg actacctgct gggcggcagg
     9181 gactactacg cggcggacag caaggccgcg gagaacgcgc tggccgccgc gccgacgctg
     9241 cgcatcgcgg cgcaggagaa ccgcaagttc atcgcgcgcg ccgtgcgcca cctcgtgctg
     9301 gacgtcggca tccggcagtt catcgacctc ggtcccggcc tgcccaccac ggagaacgtg
     9361 caccaggtcg cccaggaggc cgaccccgag gcgcgcgtgg tctacgtcga caacgacccg
     9421 atcgtattgg cgttcggcgg cgccatgctg gagcagaacg agcggaccac cgtggtgcac
     9481 ggcgacatcc gcgaccccct cgcggtcctc caccacccca ggaccaggga gcagatcgac
     9541 ccggacgagc cggtcggcgt gctggcggtc gcggtgctgc acttcataag ggacgaggac
     9601 gacccggcgg gcatcgtgcg cgccctcgcc gatgtcctcg cgcccggcag ccacttcgtg
     9661 ctctcgcacg gcacggccga catctccccg caggccgcga tgggggtgca ggccgcctac
     9721 cgttcgcacg gcgtgccgtt gacgctgcgg agcaaggagc ggttcggcga gttcttcacc
     9781 ggccttgagc tgatcgagcc cgggatacag atcgtctccg agtggcgcgc caccgagccg
     9841 gaggcggagc ggccctcctg cgaggacgtg tcctggtacg gcggtgtcgg ccgcctgtga
     9901 gggaaacgtg tgcgttcttc acgtcctcga cgtgacaccg gtgactgtct gaccggccct
     9961 ccgccgtgga aacctcattg tcacttcccg agggagggca atggacaagc ggtacgaggt
    10021 tttctgtctg gtggaccggc atttctacga ggcgccggaa cgcgccgcct cgcgcgacgg
    10081 tgcgggcggc gggcaggaag gtctgtacga aacggcgcgg cgcccggtgc cgcagggctg
    10141 gctctccgag cgtttcggcg actggctgca tctccagccg cgggacggca tcacgccgcc
    10201 gcagggctgg aagatccacg tgtccgcctg cctcgacaac gccgacaaga ccgcggcgaa
    10261 agtctgggac tattgcgtgc cgcgccgcat cccgttcaaa ttcgtgccct cggcgcaatt
    10321 gctcttcctg cgcaactcca aatacgcggg ccgccattcg agcggcaagt tcgtcacgat
    10381 ctacccggcg gacgaggacg cgctgcgcac cgtcctgacg gatcttgggg accaactggc
    10441 gggcgagccc ggcccgtaca tcctcaccga cctgcgctgg gaacgcggtc cgctgtacgt
    10501 caggtacggc ggcttcgtgc cccgctactg cgacgacggc acgggcgcgg tggtccccgc
    10561 catcgagaac gccgagggcc gtctcgttcc cgaccgcagg gggcccgcgt tcggcgtccc
    10621 cgcctgggtg acgctgcccc cgttcctcgc gccgcacctc gccgcccgca acgaggtcac
    10681 cgtcgcggca ctgccctacc gcatcgacag cgccctgcac ttctccaacg gcggcggcgt
    10741 ctaccggggc accgacaccc gcaccggcga cgcggtggtg ctcaaggagg cgcgcccgca
    10801 cgccgggctc gccgcggacg gcgcggacgc cgtcacccgg cttgagcggg agaaggccgc
    10861 gctcgaccgg ctggccgggc tggaggtggc gcccggggtg cgggactggc tgaccgtcgg
    10921 cgagcaccgg ttcctggtga tggaccacgt gccgggccgc accctcaacg cgttcttcgc
    10981 cgaacgccac ccgctgctcg ccacggaccc ggcgccggac gcggtcgcct cctacacccg
    11041 gtgggcgctc gcggtgcacc gcggcgtcga gcgggccgtc gccgccctgc acggccgcgg
    11101 cctggtcttc aacgacctgc acatgtacaa catcatggtc gcccccgacg agacctccgt
    11161 gacgctgctc gacttcgagg ccgcggcccc ggccgaggag ggcgcgcggc aggtcgtcgc
    11221 gcacccgggg ttcatcgccc cggccgaccg caccgggttc gccgtcgacc gctacgcgct
    11281 cgcgtgcctg cggctcgcgc tgttcctgcc gatgaccacg ctgttcgccg tcgaccggga
    11341 caaggcggcg cacctggcgc gggtggcgcg ccgggagttc cccgacgtgc cggccgcgtt
    11401 cttcgacgag gccgtcgccg agatcgaggg ccgccaggac cggaacgcgc gaaagcgccc
    11461 ggccgccccg cccgagccgg gtgactggcc ggcggcccgc gcctcgatgg cccgcgccat
    11521 cctggcctcg gccaccccgg aacgcgagga ccggctctac ccgggcgaca tcgcgcagtt
    11581 cggccccggc ggcgggctcg gcctggcgca cggcgcggcc ggcgtgctgt acgcgctggc
    11641 cgagaccggc gcgccgcggc atcccgaggg cgaacgctgg ctgctgcgcc gcgcggccga
    11701 tccgccgcgc aacaccccgc tcgggctcta cgacgggttg ttcggcgtcg tgcacgtcct
    11761 gcaccgcctc gggcacaccg aggccgcgct cgacctcgcg acgcgcgcgc tcggcgaggg
    11821 ctgggagcgg ctgccggccc acctgcacgg cggcctcgcc gggatcgggc tcgtcctgga
    11881 cgacctggcc gccgacaccg ggaatcccgc gctcgccgtg cacgccggtc gcgccgcgga
    11941 actcgccgcg cggcacgtcg ccgggcccgc cgagccgcgc ggccaccgca gggccggtct
    12001 gctgcacggg gccaccgggg tggcgctgct gttcctgcgc cggtacgaac ggaccggcga
    12061 gacccggctg ctcgcgacgg ccgccgccgc gctgcggcgc gacctcgcgc actgccgggc
    12121 ggaccgttcc ggggcactcc tggtcgacga gggcgaccgg ctcatgccct acctcggcga
    12181 gggcagcgtc ggcatcgcgg ccgtgctgga cgactacctg gccgcggcct cctcggcggg
    12241 actgcccgcg gaggacgacc tgacccgggc cgcggcggac atcctgcccg ccgcgcggct
    12301 gcggtactac gcgcagcccg gcctgttccg cggccgggcc gggatgatct ggcacctggc
    12361 gcgcacggcc gcgaggcccg cgccgccggg accgcgcccc gggcccgaac cggaggccgc
    12421 cctcgccgcg cagatcgacg cgctcggctg gtacgcgatg gcctacgacg gcgaactcgc
    12481 cttccccggc gagcagatga tgcgtctgtc gatggacctc ggcaccggga cagccggctg
    12541 cctgctggcc ctcggcaccg cgctgcaccg gccgggggac ccggccggcc tgccgcgcct
    12601 gccgttcctg ccgcacccgc ggcaccccaa ggcacggccc ccgtccgcct gacgagggcc
    12661 gtgggcgacc ccgcgcgggg ccgcccgtgc acgacccgtt caccttctcg aagagaggaa
    12721 ctgccatgtc ccttcttgac cttcagagca tggagcccga ggttgccagc ggcggtggcg
    12781 gcgagggcga cctcagcagc ctcagcctgc tgatctgcga cacccacagc tccaacagcg
    12841 tcatcctctg tctctgagtc caacgcccgg ggcatcccgg cggacaccgc ggccccgcgc
    12901 agcagcgcgg ggccgcgccc gtttccgcga aggagcagcg aaccgcccat gccgacgcac
    12961 cctttggacc cgaccctgcg cgccacggcc cggcagggcg ccggacgcat ggccgcgctg
    13021 ttcgcgctgt ccctcgccgc cgccggcgtg gcgctcgcgc tgcccaccgc gctcggccgc
    13081 gccctcgacg cgctgctggc cgagggggac gccacccgcg gcccggccct gctgaccgcg
    13141 ggcctggtca tcgcgcagat cctcgtcggc gtgctcacca ccgtgctcac cgccggcgcc
    13201 gacgcgcacg gcgccgcctg gctgcgcggc cggctgctgc ggcacctgct cgcggtgggg
    13261 ccgggcgccg cgagccgttt tcccgagggc gacctggtca cccgggccac ggggaacgcc
    13321 gtccacgccg gcgccgcacc cgccgccctg gccgcggcct tcgccgccgc cgcgaccccg
    13381 ctgggcgcga tcgtcgcgct ggccgtgacc gacgcgcggc tcgcgctggt cttcctcgcg
    13441 gggctgccgc tgctcgccct gctgctgcgg gcgttcgcgc ggtcggcggg cgacgcgttc
    13501 gccggctacc agcgcgccca ggcggacatc gcgggccgcc tggtggacgc gctgcgcggg
    13561 gccaggacga tcgccgccgc gggcaccgag gaggcggaac ggcgccgcgt gctcgacccg
    13621 ctgccccggc tcggcgcgca cgggctgcgg atgtggcggg tcaacgcccg cgccacgggc
    13681 cgggccgccg cgctgacgcc gctgctccag ctggccgtgg tcgccaccgg cgggctgctg
    13741 ctcgccgccg gcgacctgac cgtcggcggc ctgctcgcgg cggccaggta cgccgcgctc
    13801 gccggcggcg tcgggctgtt cgtcggccac ctcaaccggc tggtgcgcgc ccgcgccgcc
    13861 gccgtgcgcg tcggcgaggc gctggccgtg ccgccgccgc gccacggcgg cgcggcgctg
    13921 ccgcccggcg gcccggggcg cgtcgagttc cggggcgtga gcgcgcggcg cggcgggcga
    13981 gaggtgctgc gcgggctcga cctggtggtg ccgggcggca gcaccgtcgc cctcgtcggc
    14041 cgctcggggg ccggcaagtc gctgctcgcc gcgctcgccg gcggcctggc cgagcccgac
    14101 gcaggacggg tgctcatcga cggcgtgccc gtcaccgacc tggcgcccga cgcgctgcgc
    14161 gcggaggtcg gctacgcgtt cgaacgcccc gcgctgctcg gcggcacgct cgccccgacc
    14221 gtcgccgcca ccatcggcct cgggcccggc cccgcgccgc cgccggaacg cgtcgcggcg
    14281 gcggcgcggg cggcccgcgc cgacggcttc atccgcaccc tccccgacgg gtacgcgacg
    14341 cgctgcgacg gcgttccgct gtccggcggc gagctgcaac gcctcggcct ggcacgggcg
    14401 ttcgcccgcg gcggccggct gctgatcctc gacgacgcca catcgagcct cgacacggtc
    14461 acagaactgc acgtggcccg cgccctcgcc gcgcacgccg cggcccgcac ccgcctggtc
    14521 gtggcccacc gggccgggtc cgccgcccgc gccgacctcg tggcctggct cgacgacggc
    14581 cgcgtccgcg cgctggcacc gcacggccag ctgtgggccc gcgccgacta ccgggcgctg
    14641 tgggcggccg acgagcccgc gcccgccgcg cgcggtgcgg ccgcgggggc ggacggggcg
    14701 ggaggtgcgg ccggtgcgtg accacgcggt gttccggtac ctgcggcgca accgccgccc
    14761 cctggccgtc ctcgccgcgt ggggcctgct gccggccgcg cagacgttcc tcctcggcta
    14821 cggcctggcg cgcgccctgg acgacgggtt cctcgccggg cgcaccggcg tcggcctggc
    14881 ctggctggcg gcggccggcg gcggcgtgct ggccggcgcg ttcggcacca cgcgcgtgca
    14941 ccgcgccgtg ggggcgctcg ccgagccgct gcgcgacggc ctggtgcgcg aggtcgtcgc
    15001 gcgcgggctg caccgcgcgg tccgcgccgg gcggccggag agcggcaccg cggacgtgtc
    15061 ccggctgacc caccaggtcg agatcgccag ggacagcttc gccggactcg tgctcgtgct
    15121 ccagatgttc gtgtgcacgc tcgcgggctc gctggccggg ctcgcctcgc tcgcgcccgt
    15181 gctgctgccc gtcgtgctcg gcccgttgct gctcgcgctc gccctgttcg cctggtcgct
    15241 gcgtccgctg gccaggcgcc agcgcgcggt gctggtcgcg gacgaggcgc tggccgacgc
    15301 gttcggcgag accgcagggg ggctgcggga catcacggcc gcgggcgtgc ggggccgggc
    15361 cgaggcggcc gtcggcgcgc gcgtcgacgc ggagctggcc gccgcgctcg cgctcggccg
    15421 ctggggggcc gtgcgcgtgg tcgccctggg cctcggcggt caactgccga tcctgctcct
    15481 gctgttcctc ggcccctggc tgctgcgcaa cggcgtgacg ccggggggcc tgctcggcgc
    15541 gctcacgttc gtcacgcagg ccctgctgcc cgcgttgcag gcgctgctcg gcggtgtcgg
    15601 cagcgccggc acccggctcg ccgtggtgat cgcccggctg cgcaccgatc cgctgccgcc
    15661 gcagggcccg cccgccgagc cggcgcggga acgggccggg gcggcggtgg agccgtccgg
    15721 ggcggcgccg gcggaacggg ccgggccggc gcccgcgcgg gaggcgcccg cgccgggggc
    15781 gcgcgctgcg cgccggcggc cggccgtgga gctgcgcggc gtgacgttcg cctacggcgg
    15841 ccgggccgaa cccgtgctcg acggtctcga cctggccgtg ccgcccggcg ggcacctggc
    15901 cgtcgtcggg ccgagcggcg cggggaagtc cacgctcgcc gcgctggccg ccggcctgct
    15961 cgcgccgcgc gccggccggg tcgcgctgtg cgggcggccg gtggccggac gcacggccgc
    16021 ggaactggcc gcgctgcgcg tcctgatccc gcaggaggcg tacgtcttcc gcggcagtgt
    16081 cgccgacaac ctctcctacc tgcgtgccgc gcccctgccg gccgccgcgc tgaccgcggc
    16141 ggccgaggcg gtgggcgcgg gcgacctggt cgaccggctc ggcggcccgg ccgggcaggt
    16201 ggacccggcc gcgctgtccg cgggggagcg gcaactgctc gcgctgacca gggccttcct
    16261 ctccccggcc cccgtggcgc tgctcgacga ggccacgtgc cacctcgatc cggccgcgga
    16321 ggcgggggcg gagcgggcct tcgccgcccg tccgggcggc acgctcgtcg tgatcgcgca
    16381 ccggatcagc tcggcccgcc gcgcggaccg cgtgctggtg ctcgacggcg ccgaggcgca
    16441 cagcggcacc ccgagcgaac tgctcggccg ctccgccctc ttccgcgacc tggccgcggg
    16501 ctggtcagac ccatcccgcg ctcctggcga tgcggatggc gtcgacgcgg ttgcgggccc
    16561 cggtcttgcg gatgacggcg gccaggtagt tgcgcaccgt gccctccgcg agccataact
    16621 cgccggcgat ctccggcacc ggcgcgccgt ccgcggcgag ggcgagcacc cgcagctcgc
    16681 ggggggtcag gggcatgcgg gatgcgctga ggaagtcgta ggcgagcgcg tcatccacgt
    16741 aacggccgcc cttggccacc gcgcgtatgg cgtcgagcag gcgctccggc ggggcctcct
    16801 tgctgacgta gccgagggcg cgcgcctcga acgcccgggt cagcagcccg ggtctgccgg
    16861 ccggtgccag gacgaccagg ccgtgctcgt cctccgcacc cgtctgccgt accgtttcgt
    16921 ccgcgtaccg ggcgaacccg gggcaggtca cgtccgcgag ccgtaccgtg cccggtggcg
    16981 gcggctccgc cctggtcagt gcctcccagg aaagggagga aatctcgatg tccacctccg
    17041 cgcccagcag cgaggtcaat ccgcagcgca gcagagtgtc atcgtgcacg aacagtaacc
    17101 ggatcacgga tggtgcctcc tcgggcaaag actcggactc gccccccgac cccttagttt
    17161 cctcatatcc gtgtccccag gaccctggaa agtgaacccg cgtccgcgcg tgcgggaagc
    17221 acgcggggcg cacaggggcg cacagcggaa atcattcttg ccgcatttcg gacagttttc
    17281 agttccgccc gcagaaacgc aacaggggtg gtaacggaga attttccgcg tagtttttgc
    17341 ggttgccgga gagtcccgtt ccgggcccgg gtcggtcgct tccgggaatt acggaaacgc
    17401 ctcgcgaacg catgtacgcg cgaacggacg tgtgtgcgat cgaggggtgc gcgtggttcg
    17461 gcgggcgccc gtcgttcggc aggcgtgcgg cgctcggggg gcgtgcggcg ctcagggggc
    17521 ctgcggtacc gcggccgggg gttcggccgt gggggagagg cgcagcagcc tggccgccac
    17581 gaaaccggcc ccgatcagcg cgatcagaga caggccggtg ctgagccagc tgacgccgag
    17641 caggtgtccg cccaggtagc cgacgccgac gctgtatccg gtccacacca cggcggcgag
    17701 cgccgaccag ggcaggtact cgcgggtgcg gcggcgcgcc actccggcgc ccatgctgac
    17761 cacggcgcgc ccggcgggcg cgaaccgcgc cagcacgacc agggggccgc cgcgccggcc
    17821 gcgcagcgcc gtcgcgaggc gctgctgcgc cgcgtccagc cgccgtgaac gggcgatggc
    17881 gctgtcgaac ctgcgcccgc cgcgcagcgc gaggcgatgg gcgagcaggt cgccgacgac
    17941 ggaagccgtc gtcgcgcaca gcaccagcag gaacaggtgg ggcagggcct ggtcggggcc
    18001 gggtgtcggc aggcccgcga catccgcggc ggtgcccgcg gcggcggtgg ccgcggtgac
    18061 gacgagcaca ccgctgggca ggaacggcac gaagacgtcg agcaggatcg agaccgcgac
    18121 gatcacgtag atccacgggg cgtacagcag tatccccaag gtctcctgca cggtgtcccc
    18181 gattccccgt ccgactgcct gatgcgagtg cgtgttcgat gtgacgcgct cttgcacggc
    18241 gatggttccg ccgtacagcg tacgcccggg tcctccgcgc ggtgcacgcg ggtgcgtgtg
    18301 ggcgggcttc ccgaagtctg cactgtgcag ggtgaaccca gggaaaggca atcaccacga
    18361 aggagaacga tgaagattct ggcgacgggc gcggttgcca tgacggcggt gctcgcgacg
    18421 gcgggcagct cggtggccgc cgggcaggac gacatcctgt tgtacgacgc cgggcggttc
    18481 gtgccgctgg gcgagggcac cggcgtggtg cccaaagcgg tgacctacaa cgaggaactg
    18541 gtgccccccg ggtcccagat ccacgtggcg cagggcatca ggggcaactc catgctcatc
    18601 gacatcgcca cgctcggcct cgaccccggc cacacctacg gcacccacgt gcacaccgag
    18661 ccgtgcggcg ccgacccggc cgacgcgggc ggccactacc aggaccagca gggtgtcgtg
    18721 gacgaggaca gcgaggtgtg gctggacttc acggtcgacg agcgcggcgt ggggcaggcg
    18781 gaggtctaca agaactggct gttccgcgcg ggcgaggccg gttcgctcgt gctgcacgag
    18841 cggggcacgt ccgaggggca cgacgagcac ccgcccggtg acgccggcgc tcgcgtggcg
    18901 tgcttctcca tcccgttcgc gggagtgccc gcggcctgaa cgggcgcgtc cgcgggcggt
    18961 gcgccgcccg ccgccggagc ggcccgccga ccgggagagg gcccggccgg cgggccgctg
    19021 gggacccggc ggtccgggtt ccggcagtgc ggacagtggt cgttcagggc ctgacggtga
    19081 ggcggatcag gccgtcggac ggggggaagc cctcggggcg cgggcgcggt gcggcctcga
    19141 cccgcacgtt ctccagggtg gccgcgtagg cggtcggcgc gagcgccgcg gcccgggggc
    19201 cgacgccgat gacgcgcata ccggcggcgc gcgccgcttc gatgccggcc gccgagtcct
    19261 cgaagacgag gcagtcggcc ggggcgatgc cgagttcggc cgcgcccttc aggaacccct
    19321 ccgggtccgg cttgctcgcg ctgaccgact cggccgtgat ccggacctcg ggcatccgca
    19381 gccccgcggc cgacatccgg gcccgcgcca gcccggagtc cgccgaggtg accagcgcgt
    19441 gaggcgcgtg ctcgatcgcg tcgaggaacg cgccggcgcc ggggatcggg acgacgccct
    19501 cggtgtcggc ggtctcccgg gccagcagcc aggccgcgtc ggcctcgtgt tcctcgaccg
    19561 accgctcggg cagcaggtcc gccatcgtgg cgcgcgcctg ccggccgtgc atgatcgcga
    19621 agacccggac cgggtcgacg tcccgcatct cggcccaggt ccgccagacg cgttccacgg
    19681 ccgcgtccga gttgaccagg gtgccgtcca tgtcgaggag gagtgcgcgg gccgtcagcg
    19741 tgaggggcga catcgtggcg ggctccagat cgggagggaa cggccggggc cggggcggac
    19801 ggtgggaacg gtgtgcgggg gccggtgcgg gacaggagga agccagtggc cccgcccgtc
    19861 acggtcgggg aggcgggcgg aaccactttg ttttactacg gtacaaaacg aggggcccgt
    19921 cgcgccaccc cctctcgcgt tcggtgggca accgtcgccg gaagttcggc cgccattcac
    19981 gctcccgggc ccggcggccc ccgcgtcgcc cggcgcgcgg cgcccggccc gccgaggtgg
    20041 tccccgcgct cgggaccggc cggctccgcg ccgcggtcac gcaccggctt tccgcaggtc
    20101 acgggcctgc cgccgaccgg agccgcgacc gcggcacagg gcggctccgc ccgcccgcgc
    20161 cgcacgcccg gtctcccggg gaacgatgcg cgcgcgagcc cggaaccgcc cccgtgcgac
    20221 ccccgccatc ccccggacgg gtggtgcata atcgctgcca atcgatcggg agggggcagt
    20281 gtgacgatcg accggtccga gtgcctgatc tgcggccgac cggtgccgcc caccggcgaa
    20341 cccgactgcg aatgctggac ccactcgctg tcccggcccg tcgaaccgcc gctgcacggg
    20401 cccgatcccg ccgacgtcgc cctcttcccc gtggacgcct ccgcgcccgg ccagcggcag
    20461 gccccggccg gcgtgccgcg cgccgcccgc gcccccgcga gccggcccgc gccccccgtg
    20521 ccgcagcgtc ccaccggcac ccaccgcaag ccgcgcgggc gcacccgcat cgccacggcg
    20581 gccggtggcg cggtggccgc cgtggtcggc tgcacggcgc tggccgcctc gatcctcagt
    20641 ggccaggggc ggcaggagca ggcccacgaa ccggacggcg ccggcccgag cctggcccag
    20701 cccgacggcg gggacgcccg ccccgacccg ccgtcgccac cggcgcccga ccgcgagggc
    20761 gccgacgccg cgccgggccc gggacccgcc gaccccgagc ggcccgagcc ggacggcggg
    20821 gacgggacgg cgggttccga gcggcccgag tccccgaccc cggacgagga gccgtccgag
    20881 ccgccggccg acgacaggcc ggagcccgac ccggtcgatc ccgagcccac gcccgacgcg
    20941 ccgccggtcc ccggtccgga gaccccggcc acccccgagc cgcccacgcc ctcggagccc
    21001 tccgagggcg ccgcgcccgt gctcggcgca ggcgacgaag gcccggaggt ggccgaactc
    21061 cagcggcgcc tcctccagtt gaactgggtc taccgcgggc aggcgcacgg ccgctacgac
    21121 gagcagacgg ccgcggccgt ggcccgtttc caggtcgcct acggggtgcg gggggacccg
    21181 gaggggctgt acggccccca gacccggcgt gcgctggagc agcacacgcg gccgtgagcg
    21241 accgcgttca cgccgggtgc gccggcgcct cgccgggccc ctgcgcgcct tcgtgcttcg
    21301 acgcacccgc gtggctcgcc gcctcgtcac ccgccgtgga ctcgccgggc cccggcgcct
    21361 cgaagcgcgc cggcacctcg aacgccgccc gccgcgtcgc acggcgcagc gcccgcagca
    21421 cgctgccgcc gcacagcagg atcagcacga cggtcagcag cgcgcgcggc acgtcccagc
    21481 cgagcgaggt ggtggccacg taggcggcgt agcgggccag gttgtccggc agcgggtcgc
    21541 cgggcacgaa ggagatgccg ctgctcatgc ccgccaggta gggccagccc tggaggttca
    21601 tcacgagtcc gtaggcgagc gaggccagcg cgccgtagcc ggcgagcagg gcgagttcgg
    21661 cccgcccgcg cagccggtgc gcgccgggca gcagcccggc gcccatggtc agccagccca
    21721 tcgacagcat ctggaacggc agccacgggc cgacgccccc ggtcaggagc gcggaggcga
    21781 acatcgacac cccgccgagc acgaacccga acccgggccc gagcacccgg ccggacagca
    21841 ccatcaggaa gaacatcggc tggagccccg ccgtgcccgc gcccagcggg cgcagcgcgg
    21901 cccccgccgc ggccagcacg ccgagcatcg cgacggcctt ggcgtccagg ccggtgtccg
    21961 cgatcgtggc gaccacgacg gcgagcagca gcggcagcag cagcgcgaac agccagggcg
    22021 cgtccgccga gtgcgcgagc cctgaggcgg agtccgcgag cagcggccag ccgaacgcca
    22081 cgaccccggc cgccgagacc aggacgagcg ccgcggcgga acgcggaccg aggcgcacgg
    22141 gggcggggcg ccgctcccgc gccggggcgc cggagcgttt ccgtgtttcg gaagcacgcc
    22201 ggggcgcgcg ctgttccctc acgcgccacc gtccgtcggc cggtcgagcc ccgcccgcac
    22261 ctgcgcgacg gtcagccacg gcgccggcgc caataccttg gccacctgag gggcgaacgc
    22321 gggcgaggcc gtcacgacct cggccgtcgg cccgtccgcg acgacctcgc cgtccgccag
    22381 taccacggtg cgcgcggcga gttcggcggc gagttccacg tcgtgcgtgg cgagcaggac
    22441 gcagtgcccc tcgtccgcca gttcccgcag gcaggccacc agcctggcct tggccgcgta
    22501 gtcgaggccg cgcgtcggct cgtcgagcag cagcacgggc ggggccgcgg ccagcacgac
    22561 ggcgagcgcg agcgccagcc gctgcccctc ggacaggtcg cgcgggtgcg ccgtgtcccg
    22621 cacgccgggc agcagccgcg tcagcagggc gc
//
