LOCUS       NZ_CP021121            24335 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Streptomyces marincola strain SCSIO 03032 chromosome, complete
            genome.
ACCESSION   NZ_CP021121
VERSION     NZ_CP021121.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6287975)
  AUTHORS   Ma,L., Zhu,Y., Zhang,W., Zhang,G., Tian,X., Zhang,S. and Zhang,C.
  TITLE     Complete genome sequence of Streptomyces sp. SCSIO 03032 revealed
            the diverse biosynthetic pathways for its bioactive secondary
            metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6287975)
  AUTHORS   Ma,L., Zhu,Y., Zhang,W., Zhang,G., Tian,X., Zhang,S. and Zhang,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2017) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            164 West Xingang Rd., Guangzhou, Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2016
            Assembly Method :: Hierarchical Genome Assembly Process v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 165.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002128305.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 06:55:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,513
            CDSs (total)                      :: 5,438
            Genes (coding)                    :: 5,343
            CDSs (with protein)               :: 5,343
            Genes (RNA)                       :: 75
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 19 of 95
            Pseudo Genes (incomplete)         :: 88 of 95
            Pseudo Genes (internal stop)      :: 2 of 95
            Pseudo Genes (multiple problems)  :: 13 of 95
            CRISPR Arrays                     :: 12
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 415717
            Orig. end                         :: 440052
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021121.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Key Laboratory of Tropical
            Marine Bio-resources and Ecology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24335
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24335
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24335
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14335](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14335)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            243..1484
                     /locus_tag="CAG99_RS01520"
                     /old_locus_tag="CAG99_01515"
     CDS             243..1484
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432665.1"
                     /locus_tag="CAG99_RS01520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01515"
                     /product="transglycosylase family protein"
                     /protein_id="WP_086157205.1"
                     /transl_table=11
                     /translation="MTSRGRHRRYRPSAVSRASLTVTASGAGLAIPLLGAGVAAAAPVD
                     TWEEVAECESNGRWDINTGNGFFGGLQFQQSTWESYGGTGYAPRADLATRDQQIAVAEE
                     VLDGQGPQAWPACAAEAGLTRDGVRPAIAPADAPGPAPAAERAPAAEESATRTSTPAGR
                     GERAGDLYEVVRGDTLSGIASAKDVRGGWQSLYELNRRTVGGDPDLILPGQRLALRAPA
                     EGGTEEREEEREAAEPRQEPAAEEPREAPEPEPAPEPEPEPAEQPQGEREEQPAEAAPA
                     YTAPVSAGTGTAYRSSGGSWSLGYHTGVDFPVPTGTSVKSVAAGTVVSAGWAGSFGYEV
                     IVRHPDGHYSQYAHLSAISVSEGQSVTTGRQVGRAGSTGNSSGPHLHFEIRTGEGFGSD
                     VDPVAYLRGHGVSL"
     misc_feature    1542..1560
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.26"
                     /tool="antismash"
     misc_feature    1579..1596
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.77"
                     /tool="antismash"
     misc_feature    complement(1981..1994)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.58"
                     /tool="antismash"
     misc_feature    1982..1995
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.58"
                     /tool="antismash"
     misc_feature    2121..2135
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            2172..4277
                     /locus_tag="CAG99_RS01530"
                     /old_locus_tag="CAG99_01525"
     CDS             2172..4277
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432667.1"
                     /locus_tag="CAG99_RS01530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01525"
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="WP_255308381.1"
                     /transl_table=11
                     /translation="MRRFTALWARAVHPRALTSLPVPEFEAVLLPLARRLADALGAARF
                     DPAPGRAVGAALVGARCPADALPSVLDVIDSGLVAHCGPPQGPDRPAPDELRARCTRLQ
                     HAVSAGFARALQERTRTEQEAVSRAALAARTEMTDALHESEARFRAVFKGAALGIGIAD
                     MDGTIIDVNDALGQMFGSTEEQVRSRNVLEWASPDDRPEAWRMLEELMRGTRDHYQVEK
                     SYHRSDGTMLWTNLTVSLLRDPAGGPRYLLAMMEDVTERRLLTLRLRYQATHDALTDLP
                     NRSLFFERLEQALDRGGQGTARIGLCYLDLDGFKAVNDSLGHAVGDQLLIAVAERLQRC
                     ASGPGQLLARIGGDEFVALVIDPPDRRAVTDLAERALDALSSPVEVGGRELLVRASIGV
                     VEGPARHLTSAEVLRSADITMYRAKAEGGNRYAVADPDSDARAISRHHLTHHLPAALKG
                     CEFFIEYQPLVRMGDGSLEGAEALVRWSHPRHGVLGPDRFIPLAEHTGLIVPLGQWVLK
                     EAVRQACQWQVRGIGGTRPLKVNVNLSPRQLHHPDLVDDTVAVLEESGLDPSALCLEVT
                     ETAMVSADESELRPLRELAEYGVGIALDDFGTGYSNLANLRRLPASTLKLDRSFTQGLQ
                     RDPADPVDLKIVEGIVSLAHTLQLSVTVEGVETSVQAEQLRDLGCDSAQGWYYARPGPP
                     ERLPEAV"
     gene            complement(4327..5490)
                     /locus_tag="CAG99_RS01535"
                     /old_locus_tag="CAG99_01530"
     CDS             complement(4327..5490)
                     /EC_number="2.7.1.170"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852478.1"
                     /locus_tag="CAG99_RS01535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01530"
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="WP_255307922.1"
                     /transl_table=11
                     /translation="MLSGTSLDAVDAAVAEFAFDGPDLLLRPAGLHTEPYPAELRDELA
                     ACLPPAATTFGQVCRLDTRLGQFFGRVAARANDGLARGRADLVASHGQTVHHWVADGRA
                     RGTLQLGAAAWIAEATGLPVVSDLRTRDIARGGQGAPLAATLDALLLLTGTDGTGRGAL
                     NLGGIANITVRDAAGGIVAYDIGPANALIDAVAAEASGGAERMDTGGARAARGTVDPGL
                     LALLLAEPYYRLPPPKSTGKELFHAEYLADLLRRLGRRPADDDLAATVTELTARLVGAA
                     CRAHGLTELVVSGGGVRNPVLMDRVRALAAPAHVVPVERFGLPAQAKEAYLFALLGFLT
                     AHGLAGSVPSATGAAAPALLGSLTPGAGPLVLPRPRTAPPRRLRVVP"
     gene            5654..7390
                     /gene="metG"
                     /locus_tag="CAG99_RS01540"
                     /old_locus_tag="CAG99_01535"
     CDS             5654..7390
                     /EC_number="6.1.1.10"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354743.1"
                     /locus_tag="CAG99_RS01540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01535"
                     /product="methionine--tRNA ligase"
                     /protein_id="WP_086157209.1"
                     /transl_table=11
                     /translation="MARHLITSALPYINGIKHLGNMVGSMLPADVYARYLRGRGHDVLY
                     ICATDEHGTPAELAAKAAGLPVAEFCARQHEAQKAVYDGFGLRFDHFGRTSSAQNIEIT
                     QHFARRLHENGFIEERSTRQVYSLADGRFLPDRYIVGTCPYCGYEAARGDQCENCTRVL
                     DPTDLLEARSAVSGSTELEVRETTHLFLLQSKLEREVEAFVDAAGEEWPTLSSSIARKW
                     LTEGLHDRAITRDLEWGVPVPADVWPELAAEGKVFYVWFDAPIGYIGATKEWADAAGAG
                     EERDWRAWWYDADASVRYTEFMAKDNVPFHTVMFPATQLGTREPWKKVDVVKSFNWLTY
                     YGGKFSTSQNRGIFADAALDVLPADYWRYFLIAGAPESDDASFSWELFASVVNKDLADT
                     LGNFVNRVLTFSRKRFGDQVPAGHAAGEAEQRLGAEIARLLAEYEEHLSALQFRKAAFA
                     LRALWSAGNSYLEEKAPWQQIKTDQDAAALTLRTAMNLIDLYAVVSAPVIPFACETLRS
                     VFATGAGGDGERTDGWVTAEAARSLDSVPAGTDFTVPPVLFAKITDDDLEGFRQRFGGE
                     AG"
     gene            complement(7475..8863)
                     /locus_tag="CAG99_RS01545"
                     /old_locus_tag="CAG99_01540"
     CDS             complement(7475..8863)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="CAG99_RS01545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01540"
                     /product="sensor histidine kinase KdpD"
                     /protein_id="WP_086157210.1"
                     /transl_table=11
                     /translation="MPEQPRHGAGAPRHSRLAFGEPGGGEPGTRRRLLRLAVLPAVLVA
                     VIATAALVYVLTRGGPGTGRGGCPVWAVLATALVLVCAVVAGAAISAAGEARAHGARLT
                     GLRRQAARGRVELQALLVKVERGERIRPPEGPAPAEPAEDQLDQLRHEIEAAQHAAESA
                     VFQASSLVRGGEDERVEVFVSLARRLQSFVHRQIEYLEELEEEVEDPELLKGLFHVDHL
                     ATRVRRHAENLAVLGGAVPRRQWSRPVGMSEVLRSCVAEVEHYSRVKLVPPIEGSVRGH
                     AVADVIHLLAELVENATEFSAPQTQVLLRVQRGAAGIAIEVEDRGLGMTPAEQVRMNAV
                     LAGAERADVTELLEDGRVGLFVVATLARRHGIVVQLQSNVYGGVQAVLMLPSDLLGDDS
                     DADHVRGRAIRAIEAAPRDGLPHAPLPRRPSLVPGTAGGEDAPAPGLIAASPGPAGRPE
                     DADA"
     gene            complement(9004..9702)
                     /locus_tag="CAG99_RS01550"
                     /old_locus_tag="CAG99_01545"
     CDS             complement(9004..9702)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125960.1"
                     /locus_tag="CAG99_RS01550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01545"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_086157211.1"
                     /transl_table=11
                     /translation="MDDDTLFPRERVEIAPGAVHLPGWLGRERSADLLAACRAWALPPA
                     GLRTVLMPNGGRMSVEQVSLGWHWYPYGYARTVVDGDGAPVKPFPAWLGAWAGQAVADA
                     GPGAEAAAHAPAALPFDIALVNFYGPGARMGMHRDSDERVPAPVVSFSLGDTCLFRFGT
                     PEGRGRPWQDIELRSGDAFVFGGPSRLAYHGVPRTRPGSAPAGLGLSGRLNVTVRVSGF
                     SAAEDGVPQA"
     gene            complement(10001..11059)
                     /locus_tag="CAG99_RS01555"
                     /old_locus_tag="CAG99_01550"
     CDS             complement(10001..11059)
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019993176.1"
                     /locus_tag="CAG99_RS01555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01550"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_086157212.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.8e-55, bitscore:
                     184.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPAHTDGAVPALLERGRALAAPALREAVGRLAPPMNTVAAYHF
                     GWIDADGRPAASDSGKAIRPALALLSAEAAGAAPETGVPGAVAVELVHNFSLLHDDLMD
                     GDEQRRHRDTVWKVHGPAQAILVGDALFALANEVILAPGTADAARAARRLAAASRRLVD
                     GQAQDIAFEHREHVTVAECLEMEGNKTGALLACAASIGAILGGADDALAESLELYGQHL
                     GLAFQAVDDLLGIWGDPRSTGKRTWSDLRQRKKSLPVVAAQAARGPAAERLTALLTADA
                     KKTQEEFDDFDEAEFATRAALIEEAGGRVWTEGEARRQYDAAVAALHRVDVPGPVRDRL
                     TALADFVVVRQK"
     gene            complement(11056..12477)
                     /gene="hpnE"
                     /locus_tag="CAG99_RS01560"
                     /old_locus_tag="CAG99_01555"
     CDS             complement(11056..12477)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848333.1"
                     /locus_tag="CAG99_RS01560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01555"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_086157213.1"
                     /transl_table=11
                     /translation="MTSTRRPGHTVVIGGGLAGTTAALALADAGRAVTLVESRPRLGGL
                     AFSFRRDSPAGPLTVDNGQHVYLRCCTAYRGFLQRVGAAALAPLQPRLDVPVLDAATGR
                     LGRIRRTGLPVPLHLAGSLARYPHLSPGERAAAARATLALRALDPGDPRLDRQDFAAWL
                     RRHGQTDRAVAALWDLIGVATLNARAGDVSLGLAAMVFRTGLLTAPGAADLGIPRAPLG
                     ELHDTRARAALDRAGVTTLLSTRARRLAPARGGGWHVTVAAPRGLPGAAHELTADSVVL
                     AAPHDVAARLLPAGAMTDPGGLRHIGTAPILNVHVVYDRQVLRRPFLAALGSPVQWIFD
                     RGGPSGLGAPGPGRPQYLALSQSAAGEEIQLPTDVLRKRYLPELARLLPRAARARVTDF
                     FVTRERAATFAPAPGVGRLRPGPRTRAAGLYLAGAWTATGWPATMEGAVRSGHAAARAV
                     LAGGPAPEHTTEESE"
     gene            complement(12474..13403)
                     /gene="hpnD"
                     /locus_tag="CAG99_RS01565"
                     /old_locus_tag="CAG99_01560"
     CDS             complement(12474..13403)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="CAG99_RS01565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01560"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_086161929.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.5e-61, bitscore:
                     205.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.4e-67,
                     bitscore: 224.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTRSPLPPAVVAAYRYCESIAEQHARNFSYGARLVPAPKRRALT
                     AVYAFARRVDDIGDGDLAPEAKEERLAAGRAMLARVRDGAVPEDDTDPVAVALAHAGRR
                     FPIPLDALDELIDGVLMDVRGHTYETWEDLRVYCTRVAGTIGRLSLGVFGVRPGAPGTE
                     RAEEYADTLGLALQLTNILRDVREDAERGRVYLPAEDLRKFGCPEGPDVVAPGRDADFT
                     GLIRFEVRRARELFVQGSRLLPLLDRRSGACVTTMAGIYHRLLDRIEAEPRAVLRGRVT
                     LPAGHKALVAARGLTGLDARRAARRERL"
     gene            complement(13415..14335)
                     /gene="hpnC"
                     /locus_tag="CAG99_RS01570"
                     /old_locus_tag="CAG99_01565"
     CDS             complement(13415..14335)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016907916.1"
                     /locus_tag="CAG99_RS01570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01565"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_086157214.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 9.2e-42,
                     bitscore: 141.6, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 1.1e-37, bitscore:
                     128.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTAEHSDAGPDGGRAVLAKAAHENFPVAPRFLPAAWRDDLMALY
                     GFARLVDDIGDGDLAPGGADAAHLGVDPAGAVDRLLLLDAVEADLRRVFASATGGTPPR
                     HPLLRELIPTVRRSGLTPRPFLDLIEANRVDQRVRRYATYADLLGYCELSANPVGRLVL
                     AVTGTATPERVRRSDAVCTALQLIEHLQDVAEDLARDRIYLPAEVMDRFFVTEADLAAP
                     TANASVRTLVAYLTDRARRLLEEGAPLMSGVSGRLRLLLAGFIGGGHAAARAIEDAGYD
                     VLAGPPRASKGGLLYAAATTLRRGT"
     misc_feature    14374..14389
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.92"
                     /tool="antismash"
     misc_feature    14381..14395
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.0"
                     /tool="antismash"
     gene            complement(14445..15239)
                     /locus_tag="CAG99_RS01575"
                     /old_locus_tag="CAG99_01570"
     CDS             complement(14445..15239)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004951780.1"
                     /locus_tag="CAG99_RS01575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01570"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_086157215.1"
                     /transl_table=11
                     /translation="MAEQDISTGGPGGQRVPTVIADGLHIVYRVHGGGGRGTATAALRR
                     MVRRERGFKMREVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPPERGKVYT
                     DGQPSLLGVNAALMNDLTGERNVILGGLAMGMSRDEIKGRYQEIVDFSGINEKGDFISL
                     PMRTYSSGMQARLRFSIAVAKEHDVLMIDEALATGDKKFQRRSEAKVREMRAEAGTVFL
                     VSHNNKSIRDTCDRVLWLEKGELVMDGPTDQVLKAYEEETGK"
     gene            complement(15232..16146)
                     /locus_tag="CAG99_RS01580"
                     /old_locus_tag="CAG99_01575"
     CDS             complement(15232..16146)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432679.1"
                     /locus_tag="CAG99_RS01580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01575"
                     /product="ABC transporter permease"
                     /protein_id="WP_255307923.1"
                     /transl_table=11
                     /translation="MSETTHDSAPPRDVPLAELAARHGLSVSGARPSLPGYVRQLWGRR
                     QFIVAFSQAKLSAQYSQAKLGQIWQVLTPLLNALVYYLIFGLLLQGRGNMENEEYVPFL
                     VTGVFVFTFTQNSVMSGVKSISGNLGLVRALHFPRASLPISLSLQQLQQLLFSMVILFA
                     IVVAFGHFPEFNWLLVIPALLLQLVFNTGLALFFARLGSATPDLSQLMPFVLRTWMYAS
                     GVMFPLQYMVEERAEGPAWLADVLAANPAAVYMDLVRYALIDGAYRDSVEPVTWLFGLG
                     WALVVGIGGFVYFWKAEERYGRG"
     gene            complement(16227..17072)
                     /locus_tag="CAG99_RS01585"
                     /old_locus_tag="CAG99_01580"
     CDS             complement(16227..17072)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888991.1"
                     /locus_tag="CAG99_RS01585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01580"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_086161930.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-08,
                     bitscore: 33.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDRPEALRALLDSVAAQDGTAIDVVVVGNGVRLPGLPPGVRSLE
                     LPRNLGIPGGRNVGIEAFGPGGSEVDVLLFLDDDGRLPDKNVAETVRAAFEADPQLGIV
                     SFRITDPESGTTQRRHVPRLRASDPSRSSRVTTFLGGANAVRTHVFQQVGGLPDNFFYA
                     HEETDLAWRALDAGWHIDYRADLVLHHPATAPSRHAVYHRMIARNRVWLARRNLPLPLV
                     PVYLMNWLLLTLLRRPSRPALAAWFGGFVEGWRTPCGPRRPMRWRTVWRLTRLGRPPVI
                     "
     gene            complement(17120..17905)
                     /locus_tag="CAG99_RS01590"
                     /old_locus_tag="CAG99_01585"
     CDS             complement(17120..17905)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962488.1"
                     /locus_tag="CAG99_RS01590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01585"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_086157217.1"
                     /transl_table=11
                     /translation="MSKPSVAELRPVVHPPGVKDRRSGEHWAGRLYMREISLRWTRHLV
                     NTRISPNQLTYLMVLAGVAAGAALLVPGLAGAVAAALLIQLYLLLDCVDGEVARWRGQT
                     SITGVYLDRVGHYLAEAALLVGFGVRAADVFAAEEAAPNWLWAFLGTLAALGAILIKAE
                     TDLVDVARTRGGLPAARDDAAIPRSSGLALARRAAAALKFHRLVGGVEASLLILLVAVL
                     DLARDDLFFTRLGVALLAAVALVQTLLHLVSVLASSRLR"
     gene            complement(17883..18944)
                     /locus_tag="CAG99_RS01595"
                     /old_locus_tag="CAG99_01590"
     CDS             complement(17883..18944)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308910.1"
                     /locus_tag="CAG99_RS01595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01590"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_086157218.1"
                     /sec_met_domain="Fe-ADH (E-value: 5.7e-21, bitscore: 73.0,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVSVDIMAGALDNLAGLLADQRISSSGRLAVAISN
                     GSGAALRDRLAPALPGADWYEVAGGTIDAAVQLADAMRPGHYDAVVGLGGGKIIDAAKY
                     AAARVGLPMVAVATNLSHDGICSPVSTLDNDAGRGSYGVPTPIALVIDLDVIRRAPVRY
                     VRSGIGDALSNISAIADWELSHRETGEQIDGLAAAMARQAGEAVLRHPGDCGDDAFLTV
                     LSEALVLSGIAMSIAGHTRPSSGACHEISHALDVLHPRRSAPHGEQVGLGAAFAMHLRG
                     AVDQCGLIAETLRRHGLPVLPGHIGFSADEFVAAVAFAPRTRPGRYTILEHLDLSTDQI
                     RDAYADYVKTIGS"
     gene            complement(18932..19696)
                     /locus_tag="CAG99_RS01600"
                     /old_locus_tag="CAG99_01595"
     CDS             complement(18932..19696)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640650.1"
                     /locus_tag="CAG99_RS01600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01595"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_086157219.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.1e-11, bitscore:
                     40.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVIDAEGENGRTVLDLTLA
                     NFAEVGLTEAAIVVGYRKEAVYERKDALERSYGVRLTLIDNDRAEEWNNAYSLWCAREV
                     IEEGVILANGDTVHPPSVERTLLAAQAAGGPGTGRVILALDTVKKLADEEMKVVADPEK
                     GVRRITKLMDPAEATGEYIGVTLIEPGAAAPLADALRTTFERDPQLYYEDGYQELVHRG
                     FRIDTAAIGDVSWVEIDNHDDLARGREIACRY"
     gene            complement(19693..21531)
                     /locus_tag="CAG99_RS01605"
                     /old_locus_tag="CAG99_01600"
     CDS             complement(19693..21531)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676195.1"
                     /locus_tag="CAG99_RS01605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01600"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_086161931.1"
                     /transl_table=11
                     /translation="MSTAILTGPPPPGSPLESDLRELGFSVLVLDAAAGLAAELTAVPP
                     GHRVAVVDPRFVGHRHSLRLGLTDPRFAVAALPGAVTALPEGRAALAAAAAEAAPPPRP
                     PAGTHGRAVAAPPAGTCLPEELAARLTAAGSPPHRPELGTLVAAVPTTTQQRARAEADM
                     AAVDEEAVRLRSAVKARDGFFTTHFVSPYSRHLARWCARRGLTPNQVTTASLVTALIAA
                     GCAATGTRGGFVAAGLLLLLSFVLDCADGQLARYALRYSTLGAWLDATFDRAKEYAYYA
                     GLALGAARGGDDVWALALGAMVLQTCRHVVDFAFNEAHPPAPGGAAGATALSGRLDRIG
                     WTVWLRRVIVLPIGERWALIALLTAFTTPRATFVVLLVAAGLAACYTTAGRLLRSRRLP
                     GGGPGTAAALGGLADNGPLAEAAARVRPRPAGSALTAPLWAAAGTALLVGLLLVPGVAG
                     GSAAVAAAVAYAVCAGRATAAPLVRPFDWVLPPLFRGGEYLAVLVLAAESGVNGALPAA
                     FCLVAACAYHHYDTVYRLRGGAGAPPRRLVLVTGGHEGRVLVVSSAAALWAGGQGFTVA
                     LAVLGGATAFLVLGESIRFWISAQAPAVHDETGEPA"
     misc_feature    complement(21581..21597)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.32"
                     /tool="antismash"
     misc_feature    complement(21622..21637)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.07"
                     /tool="antismash"
     gene            21776..22750
                     /gene="galE"
                     /locus_tag="CAG99_RS01610"
                     /old_locus_tag="CAG99_01605"
     CDS             21776..22750
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-205). E-value:
                     5.2e-11. Score: 34.1. Matches aSDomain:
                     nrpspksdomains_CAG99_RS01610_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018838714.1"
                     /locus_tag="CAG99_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01605"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_086157220.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.8e-17, bitscore:
                     60.6, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.2e-14,
                     bitscore: 50.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWLITGGAGYIGAHVVETMRAAGERVVVLDDLSSGRAGRLPADV
                     PLVRGSVLDRDLLDTALAEHGVRGVVHLAAKKQVAESVAEPLAYYRSNVHGLTVLLDAV
                     VAAGVREFVFSSSAAVYGTPETGTVTEDTPCRPLSPYGETKLAGEWLVRAAGRAHGIAT
                     ACLRYFNVAGATRPELADAGAANVVPMFFERIAAGRPPEIFGADYPTPDGTCVRDYVHV
                     ADLADAHLLAARHLTEAAPGDDLTVNVGTGRGASVRELAALVADVTGFAGPPRVADRRP
                     GDPARVVASVELARERLGFTARRGLPDMVSSAWEGWRRAHGGL"
     CDS_motif       21779..21865
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAG99_RS01610_0001"
                     /evalue="2.00E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="CAG99_RS01610"
                     /protein_end="30"
                     /protein_start="1"
                     /score="14.0"
                     /tool="antismash"
                     /translation="SWLITGGAGYIGAHVVETMRAAGERVVVL"
     aSDomain        21974..22390
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAG99_RS01610_NAD_binding_4.1"
                     /evalue="5.20E-11"
                     /label="CAG99_RS01610_NAD_binding_4.1"
                     /locus_tag="CAG99_RS01610"
                     /protein_end="205"
                     /protein_start="66"
                     /score="34.1"
                     /tool="antismash"
                     /translation="VRGVVHLAAKKQVAESVAEPLAYYRSNVHGLTVLLDAVVAAGVRE
                     FVFSSSAAVYGTPETGTVTEDTPCRPLSPYGETKLAGEWLVRAAGRAHGIATACLRYFN
                     VAGATRPELADAGAANVVPMFFERIAAGRPPEIFG"
     CDS_motif       22220..22339
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAG99_RS01610_0002"
                     /evalue="2.00E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="CAG99_RS01610"
                     /protein_end="188"
                     /protein_start="148"
                     /score="1.2"
                     /tool="antismash"
                     /translation="EWLVRAAGRAHGIATACLRYFNVAGATRPELADAGAANVV"
     misc_feature    complement(22829..22843)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            22915..23847
                     /locus_tag="CAG99_RS01615"
                     /old_locus_tag="CAG99_01610"
     CDS             22915..23847
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133326.1"
                     /locus_tag="CAG99_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CAG99_01610"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_086157221.1"
                     /transl_table=11
                     /translation="MGAGHHHGGPPQGGTAGAAHRRRLTAALAIACVLLVAELVGAALT
                     GSLALLADAGHVATDAVGIGMALVAIHVANRPVRSDRRTFGFARVEVLAALANCVLLLG
                     VGGYILVEAIGRLREPAEVPGGLTVVFGVAGLLLNCLSLALLMRGQRESLNVRGAFLEV
                     AADALGSVAVVAAALVIMFTGWQAADPVASLLIALLIVPRAVRLAREAIDVLLETAPKD
                     VRIAEVRDHVLGLPGVEGLHDLHVWTITSGMPALSAHVVVARETLDAVGHEEMLHALQG
                     CLGEHFDVAHCTFQLEPSGHAAHEPGLCH"
ORIGIN
        1 cgacgccccg agtgccccgg cgccgcagga cccctgaccc gccgtcacac gcctgccgcg
       61 gggcccgcgg tgccgcccgt gcccgggggc cccgcgccgt tcgaccgggg tccgcaccag
      121 cctcccggct cccttgccgc gcgcgacccg gcgcccatat cgttgtgccg ccgcacgacg
      181 cgcccgatcc gcacgtgggc cgacggggcg tcccagcact cggccaggga ggggacccgc
      241 ccatgacctc acgtggacgt caccgtcgtt accgaccgag tgcggtgtcc cgcgcctcgc
      301 tgaccgtcac cgcctcgggc gccgggctcg ccatcccgct gctgggcgcc ggcgtcgccg
      361 cggcggcccc cgtcgacacc tgggaggagg tcgccgagtg cgagagcaac ggccggtggg
      421 acatcaacac gggcaacggc ttcttcggcg ggctccagtt ccagcagagc acgtgggagt
      481 cctacggcgg caccgggtac gcgccgcgcg ccgacctcgc cacccgtgac cagcagatcg
      541 ccgtcgcgga agaagtcctc gacgggcagg gcccgcaggc ctggcccgcg tgcgcggccg
      601 aggcgggcct cacccgggac ggcgtgcgcc ccgccatcgc gcccgccgac gccccaggac
      661 ccgcgcccgc cgcggaacgg gcgcccgcgg ccgaggagtc cgcgacgcgg acgagcaccc
      721 cggccgggcg cggcgagcgc gcgggcgacc tgtacgaggt ggtccgcggc gacaccctgt
      781 ccggcatcgc gagcgccaag gacgtgcgcg gcggctggca gtcgctctac gagctcaacc
      841 gccggaccgt cggcggcgac ccggacctca tcctgccggg acagcggctc gcgctgcgcg
      901 cacccgccga aggcggcacg gaggagcggg aggaggagcg ggaggccgcg gagccgcgcc
      961 aggagccggc cgccgaggaa ccgcgcgaag caccggaacc cgagccggcg cccgagcccg
     1021 agcccgagcc ggccgagcag ccgcagggcg agcgcgagga gcagccggcc gaggcggccc
     1081 ccgcctacac cgcgccggtc agcgcgggca ccggcaccgc gtaccgctcc tcgggcggct
     1141 cctggtccct cggctaccac acgggcgtcg acttccccgt gccgacgggc acatccgtga
     1201 agtcggtggc ggccggcacc gtcgtctcgg cgggctgggc cggctcgttc ggctacgagg
     1261 tcatcgtccg gcaccccgac ggccactaca gccagtacgc gcacctctcg gccatctccg
     1321 tgtccgaggg ccagtccgtc accacgggcc ggcaggtggg gcgcgccggt tccacgggca
     1381 actccagtgg cccgcatctg cacttcgaga tccggacggg cgaaggcttc ggttccgacg
     1441 tcgaccccgt cgcctatctg cgcgggcacg gcgtatcgct ctgacaaccg atcacatcac
     1501 gccatccgtg gcgtgatcac ggcggtctgg cgcgcgccca ttaccggaca gatggacagg
     1561 taaccgtccc gcagaacgat gttgctccgc tgtttccttc cccgatctgc cgccgggtca
     1621 gtagtctcga ccgcctgagg ccacatcgag catatgcagg gcacattgga gacgccgatg
     1681 gaacgttccg cctgggcgcc gcccggcgtc ggtccgtccg tcctcccccc gccccgcacg
     1741 cgtgccctcc ccccgggcgg gccccgcggc tccctggccc accgcacggc ggcccccgcg
     1801 ctccccggcc cggtgggcgg cgcgtccgcc caccggccgg acggcgccca ccggccggac
     1861 ggcgccgccc ggcccgtcgc cccgccgccg gccgccgtgc cgcaccgccc cggcggtggt
     1921 gaacgccgcc ggtgcgacgc gacgccgcgc tcgcgccccc gcgcgcggtc cgcgcgcttc
     1981 ttcgaccgtt tccaacacga cgccccgggc gtggtcccgt tgcccgaagg gcggcccgac
     2041 acgccgcccg acgaggaggg gcccatggcc cacggcggtt tcgcggaagt aggacgcaca
     2101 gggtgacatc ctcgccaccg gggccgaccg gccaccatcg caccggaacg ggtcaggagc
     2161 cgtccgccgg cctgcgccgt ttcaccgccc tctgggcccg cgccgtccat ccccgcgccc
     2221 tcacgtcgct gccggtaccg gagttcgagg cggtgctgct gccgctcgcc cgccgactgg
     2281 ccgacgcgct gggcgccgcg cgcttcgacc ccgcgcccgg ccgggccgtc ggcgccgcgc
     2341 tcgtcggcgc ccgctgcccg gccgacgcgc tcccgagcgt tctcgacgtg atcgactcgg
     2401 ggctggtcgc gcactgcggc ccgccacagg ggccggaccg accggcgccc gacgaactgc
     2461 gcgcccgctg cacacggctc cagcacgccg tgtccgccgg cttcgcccgg gccctccagg
     2521 agcgcacgag gaccgagcag gaggcggtct cgcgcgccgc gctcgccgcg cggacggaga
     2581 tgaccgacgc gctgcacgag agcgaggcgc ggttccgcgc ggtgttcaag ggcgccgcgc
     2641 tcggcatcgg catcgccgac atggacggca cgatcatcga cgtcaacgac gcgctcggcc
     2701 agatgttcgg cagcaccgag gagcaggtgc gcagtcgcaa cgtgctggag tgggcgagcc
     2761 cggacgaccg ccccgaggca tggcgcatgc ttgaggagct gatgcgcggc acccgggacc
     2821 actaccaggt cgagaagtcc taccaccgtt ccgacggcac gatgctgtgg acgaacctga
     2881 cggtctcgct gctgcgcgac ccggccggcg gaccccgcta cctgctggcc atgatggagg
     2941 acgtcaccga gcggcgcctg ctcaccctcc gcctgcgcta ccaggcgacc cacgacgcgc
     3001 tgaccgacct gcccaaccgc tccctgttct tcgaacggct ggaacaggct ctggaccgcg
     3061 gcgggcaggg cacggcccgg atcggcctgt gctacctgga cctcgacggc ttcaaggccg
     3121 tcaacgacag cctcggccac gccgtcggcg accagctgct gatcgccgtc gccgaacgcc
     3181 tccagcgctg cgcctcgggg cccgggcaac tgctcgcgcg catcggcggg gacgagttcg
     3241 tcgcgctggt gatcgacccg ccggaccggc gggcggtcac cgacctcgcc gaacgggcgc
     3301 tcgacgcgct gtcctcgccc gtcgaggtcg gcggccggga gctgctggtg cgggccagca
     3361 tcggcgtcgt cgagggcccg gcgcgccacc tgacgtcggc cgaggtgctg cgcagcgccg
     3421 acatcacgat gtaccgcgcg aaggcggagg gcggcaaccg ctacgccgtg gccgacccgg
     3481 actccgacgc cagggcgatc agccgccacc acctcacgca ccacctgccc gcggcgctca
     3541 agggctgcga gttcttcatc gagtaccagc cgctggtgag gatgggggac ggcagcctcg
     3601 aaggcgccga ggccctggtc cgctggagcc acccgcggca cggcgtgctc ggccccgacc
     3661 ggttcatccc gctcgcggag cacacggggc tgatcgtgcc gctgggccag tgggtgctca
     3721 aggaggccgt gcggcaggcg tgccagtggc aggtccgcgg catcgggggc accaggccgc
     3781 tgaaggtcaa cgtcaacctc tcgccgcgcc agctgcacca ccccgacctc gtcgacgaca
     3841 cggtcgcggt gcttgaggag tccgggctcg acccgagcgc gctgtgcctc gaagtcaccg
     3901 agacggccat ggtcagcgcc gacgagagcg agctgcggcc gttgcgcgag ctggccgagt
     3961 acggcgtcgg gatcgcgctc gacgacttcg gcaccggcta ctccaacctg gccaacctgc
     4021 gccgcctgcc cgccagcacg ctcaagctgg accgctcctt cacccagggc ctccaacggg
     4081 accccgcgga cccggtcgac ctgaagatcg tggagggcat cgtctcgctg gcccacacgc
     4141 tccagctgtc cgtcaccgtg gagggcgtgg agacctccgt gcaggcggag cagctgcgcg
     4201 acctcggctg cgactcggcc cagggctggt actacgcccg ccccgggccg ccggaacgcc
     4261 tgccggaagc cgtctgagcc cggccgtgcc gcgcgccggg tccggcgcgc ggcacggccg
     4321 gagccgtcag ggcaccacgc gcagtcgccg cggcggcgcg gtgcgcggcc tgggcagcac
     4381 cagcgggccg gcccccgggg tgagggagcc gagcagcgcg ggcgccgccg cgccggtggc
     4441 cgagggcacg gaaccggcca ggccgtgagc ggtgaggaag ccgagcagcg cgaacaggta
     4501 cgcctccttc gcctgcgccg gcaggccgaa ccgctcgacg ggaacgacgt gcgcgggcgc
     4561 cgcgagcgcg cggacgcggt ccatcaggac cgggttgcgc accccgccgc ccgagacgac
     4621 cagttcggtg agcccgtgcg cgcggcaggc ggccccgacc aggcgggcgg tgagctcggt
     4681 gacggtggcc gccaggtcgt cgtccgccgg gcgccggccg agccggcgca gcaggtccgc
     4741 gaggtattcg gcgtggaaca gctccttgcc ggtcgacttg ggcggcggca gccggtagta
     4801 gggctcggcg aggagcaggg cgagcaggcc ggggtcgacg gtgccgcgcg cggcgcgggc
     4861 cccgccggtg tccatgcgtt cggctccccc gctcgcctcc gcggccaccg cgtcgatcag
     4921 cgcgttcgcc gggccgatgt cgtaggcgac gatgccgccc gcggcgtcgc ggacggtgat
     4981 gttggcgatg ccgccgaggt tcagcgcgcc gcgccccgtg ccgtccgtgc cggtcagcag
     5041 gagcagggcg tcgagcgtcg cggcgagcgg agcgccctgc ccgccccggg cgatgtcgcg
     5101 ggtgcgcagg tcggagacca cgggcagtcc tgtggcctcg gcgatccagg ccgccgcgcc
     5161 gagctggagc gttccgcggg cgcggccgtc cgcgacccag tggtggacgg tctggccgtg
     5221 cgaggccacg agatccgcac gcccgcgcgc gagcccgtcg ttggcgcggg cggcgacccg
     5281 gccgaagaac tgcccgagcc gggtgtcgag gcggcagacc tgtccgaacg tggtcgccgc
     5341 gggcggcagg caggccgcca gctcgtcccg cagctcggcc gggtagggct cggtgtgcag
     5401 tcccgcgggc cgcaggagga ggtcggggcc gtcgaaggcg aactccgcga ccgcggcgtc
     5461 cacggcgtcc agcgacgtgc cgctgagcat gccgatcacc cgccacggcc ggtcccggga
     5521 aaacctggtg gggccgccgc ccggcggctc ggtaggatga gtgaagccca taaacgtgat
     5581 ccgtcgccct tcgcggcctt ctcacggcac tcacggctca ttgtctctac tcaccccatt
     5641 ggagcatccg aggatggccc gacacctcat caccagtgcg ctgccctaca tcaacgggat
     5701 caagcacctg gggaacatgg tgggctcgat gctccccgcc gacgtgtacg cgcgctacct
     5761 gcgcgggcgc ggtcacgacg tgctgtacat ctgcgcgacg gacgagcacg gcacgcccgc
     5821 cgagctggcc gccaaggcgg ccggtctgcc cgtcgcggag ttctgcgcgc ggcagcacga
     5881 ggcgcagaag gccgtgtacg acgggttcgg cctgcgtttc gaccacttcg gccggacctc
     5941 gtccgcgcag aacatcgaga tcacgcagca cttcgcgcgt cggctccacg agaacgggtt
     6001 catcgaggag cgctccacgc gccaggtgta ctcgctcgcc gacggccgtt tcctgcccga
     6061 ccgctacatc gtgggcacgt gcccgtactg cggctacgag gcggcgcgcg gcgaccagtg
     6121 cgagaactgc acccgcgtgc tcgacccgac ggatctgctg gaggcgcgct ccgcggtgag
     6181 cggcagcacc gagcttgagg tgcgggagac cacgcacctg ttcctcctcc agtcgaagct
     6241 ggagcgcgag gtggaggcgt tcgtggacgc cgcgggcgag gagtggccga cgctgtcctc
     6301 ctcgatcgcg cgcaagtggc tgaccgaggg cctgcacgac cgggcgatca cgcgcgacct
     6361 ggagtggggc gtgccggtcc cggcggacgt gtggcccgag ctggcggccg agggcaaggt
     6421 gttctacgtg tggttcgacg ccccgatcgg ctacatcggc gccactaaag agtgggcgga
     6481 cgcggccggt gcgggcgagg agcgggactg gcgcgcgtgg tggtacgacg cggacgcgtc
     6541 cgtgcggtac acggagttca tggccaagga caacgtgccg ttccacacgg tgatgttccc
     6601 cgccacccag ctgggcaccc gggagccgtg gaagaaggtc gacgtcgtca agtcgttcaa
     6661 ctggctgacg tactacggcg gcaagttctc cacctcgcag aaccggggca tcttcgccga
     6721 cgcggcgctc gacgtgctgc cggccgacta ctggcggtac ttcctgattg cgggggcgcc
     6781 cgagtcggac gacgcgtcgt tctcctggga gctgttcgcg tccgtcgtca acaaggacct
     6841 ggccgacacc ctgggcaact tcgtcaaccg ggtgctgacg ttctcgcgca agcgcttcgg
     6901 cgaccaggtg cccgcggggc acgcggccgg cgaggccgag cagcggctcg gtgccgagat
     6961 cgcccggctg ctcgccgagt acgaggagca cctgtcggcg ctccagttcc gcaaggcggc
     7021 gttcgcgctg cgcgcgctgt ggagcgcggg caactcctac ctggaggaga aggcgccctg
     7081 gcagcagatc aagaccgacc aggacgccgc cgcgctcacg ctgcgcaccg cgatgaacct
     7141 gatcgacctc tacgcggtgg tctccgcgcc ggtcatcccg tttgcctgcg agacgctgcg
     7201 ctcggtgttc gccacgggcg cgggagggga cggggagcgc acggacggct gggtgacggc
     7261 ggaggccgcg cggtcgctgg acagcgtgcc ggccgggacg gacttcacgg tgcccccggt
     7321 gctgttcgcc aagatcaccg atgacgatct tgagggcttc aggcagcgct tcggcggcga
     7381 agccggctga cacggcgccc gcggggcacc gggcctcctc cgcggggccc ggcgtcccgc
     7441 cgcggcaccg gaccggggag ccgccgccgg tcggtcaggc gtcggcgtcc tcgggccgtc
     7501 ccgcgggccc gggcgacgcg gcgatcaggc cgggggccgg ggcgtcctcg cccccggccg
     7561 tccccggcac cagcgaagga cgtcgcggca ggggcgcgtg cggcaggccg tcccgcggtg
     7621 ccgcctcgat cgcccggatg gcacgccccc gcacgtggtc ggcatcggag tcgtcgccca
     7681 gcagatcgga cggcagcatg agaacggcct gcacgccgcc gtagacgttg ctctggagct
     7741 ggaccacgat gccgtggcgc cgcgcgaggg tggcgacgac gaacaggccc acccggccgt
     7801 cctcaagcag ttcggtcacg tcggcccgct cggcgcccgc aagcaccgcg ttcatccgca
     7861 cctgctccgc cggggtcatg cccaggcccc ggtcctcgac ctcgatggcg atcccggcgg
     7921 cgccgcgctg cacgcgcagg agcacctgcg tctgcggggc cgagaactcc gtggcgttct
     7981 cgaccagttc ggccagcagg tggatgacgt cggcgacggc gtgaccgcgc acactgccct
     8041 cgatcggggg caccagcttg acccgggagt agtgctcgac ctcggcgacg caggaacgca
     8101 gcacctccga catcccgacc gggcggctcc actggcggcg cggcaccgcg ccgccgagca
     8161 cggcgaggtt ctcggcgtgc cggcgcacgc gggtggccag gtggtccacg tggaagaggc
     8221 ccttgagcag ttccgggtcc tcgacctcct cctccagctc ctccaggtac tcgatctgcc
     8281 ggtgcacgaa cgactgcaac cgccgcgcca ggctgacgaa cacctcgacg cgctcgtcct
     8341 ccccgcctct cacgagggac gatgcctgga agaccgcgga ctcggcggcg tgctgcgcgg
     8401 cctcgatctc gtgccgcagc tgatcgagct ggtcctcggc cggctccgcg ggggccgggc
     8461 cctccggcgg cctgatgcgt tcgccgcgtt ccaccttgac cagcagcgcc tggagttcca
     8521 cacgtccgcg ggccgcctgg cggcgcaggc cggtcagccg cgcgccgtgg gcccgtgcct
     8581 cgcccgcggc gctgatcgcc gctccggcga cgacggcgca gaccagcacc agggccgtgg
     8641 cgagcaccgc ccagacgggg cagccgcccc gcccggtccc cgggccgccc cgggtcagca
     8701 cgtagacgag ggccgcggtc gcgatcacgg cgaccagcac ggcggggagc acggccaggc
     8761 gcagcaggcg gcgtctggtt cccggctccc cgccgcccgg ctcgccgaag gccagccgac
     8821 tgtggcgggg cgcgcctgcc ccgtggcgtg gctgctcagg catgggtgtc cttatcgggc
     8881 gggtcaagtg ggtgcaaggc cacgctatgc gtcaacaggt aggcgaacgg gcacagttcc
     8941 ggcaatcgcc accccacgcc agctcccaac gagtgaatgc gccgggcccg gccttgaccg
     9001 gcttcacgcc tgggggaccc cgtcctccgc ggcgctgaac ccggaaacac gcacggtgac
     9061 gttgagcctg ccgctgagcc cgaggccggc cggcgcgctg cccggccggg tacgtggcac
     9121 gccgtggtag gcgagccggg acggcccgcc gaagacgaac gcgtcaccgc tgcgcagctc
     9181 gatgtcctgc cacggacggc cgcgcccctc gggggtgccg aaccggaaga ggcacgtgtc
     9241 gccgaggctg aaggacacca cgggcgccgg cacccgttcg tcgctgtcgc ggtgcatgcc
     9301 catccgggcg ccggggccgt agaagttgac gagggcgatg tcgaagggga gggcggcggg
     9361 ggcgtgcgcc gcggcctccg cgcccgggcc ggcgtcggcg accgcctgcc cggcccaggc
     9421 gccgagccag gcggggaacg gcttgaccgg cgcgccgtcg ccgtcgacga ccgtgcgggc
     9481 gtagccgtag gggtaccagt gccagccgag gctgacctgc tcgacggaca tccggccgcc
     9541 gttcggcatc aggaccgtgc gcagcccggc gggcggcagg gcccacgcgc ggcaggcggc
     9601 gagcaggtcc gcggagcgtt ctcggccgag ccagccgggg aggtgcacgg cgcccggcgc
     9661 gatctcgacc cgttcccggg ggaacagcgt gtcgtcgtcc atccgttcat cctcgcccac
     9721 gggcccgcgt accggcaggc cgattccggc gggccgcggc catggggccg ggctcgatca
     9781 ccggcggccg gccgcgcgag gcacccgccg cgtgccgcgc cgcccgcgcg ccacgaagcg
     9841 cgcacggccc tcggcctcgg gaaggccgcg aaccgggaac gcggagggag ggccgtcgac
     9901 ctggccgccg cacggggcgg cggaacgggg gcggctgcgc agcgccccac tcacggcccg
     9961 agccggccgg cccgcgcggc ggggcggggg gccgggggcg tcacttctgg cggaccacga
    10021 cgaagtcggc gagtgccgtc agccggtccc tgacggggcc gggcacgtcg acgcggtgca
    10081 gggcggcgac ggccgcgtcg tactggcggc gcgcctcgcc ctcggtccag acccggccgc
    10141 cggcttcctc gatcagcgcc gcccgggtcg cgaactccgc ctcgtcgaag tcgtcgaact
    10201 cctcctgcgt cttcttcgcg tcggccgtga gcagcgccgt cagccgttcg gccgccgggc
    10261 cccgcgcggc ctgcgccgcc accacgggca gggacttctt gcgctgccgc aggtcgctcc
    10321 aggtgcgctt gcccgtgctg cgcgggtcgc cccagatgcc gagcaggtcg tcgacggcct
    10381 ggaacgccag gccgaggtgc tggccgtaca gttcgaggct ttcggccagg gcgtcgtcgg
    10441 cgccgcccag gatggcgccg atggaggcgg cgcaggccag cagcgcgccg gtcttgttgc
    10501 cctccatctc caggcactcg gcgacggtga cgtgctccct gtgctcgaag gcgatgtcct
    10561 gggcctggcc gtcgacgagc cggcggctgg ccgcggcgag ccgccgggcc gcgcgggcgg
    10621 cgtcggcggt gccgggggcg aggatcacct cgttggccag cgcgaagagg gcgtcgccga
    10681 ccaggatggc ctgcgcgggg ccgtgcacct tccacacggt gtcgcggtgt ctgcgctgct
    10741 cgtcgccgtc catgaggtcg tcgtgcagca acgagaagtt gtgcaccagt tcgaccgcga
    10801 cggccccggg cacgccggtc tcgggcgcgg cgcccgcggc ctctgcggac agcagggcga
    10861 gcgcgggcct gatggccttg ccgctgtcgc tcgcggcggg cctgccgtcg gcgtcgatcc
    10921 agccgaagtg gtaggcggcg acggtgttca tcggcggggc gagccggccg acggcctccc
    10981 gcagggcggg cgcggccagg gcccgcccgc gttccagcag cgccggtacg gcgccgtccg
    11041 tatgggctgg ctggttcact cgctctcctc agtggtgtgt tcgggggccg ggccgccggc
    11101 gagcaccgcc cgggccgccg cgtggccgct gcggacggcg ccctccatcg tcgcgggcca
    11161 ccccgtggcc gtccacgcgc cggccaggta gaggccggcg gcccgggtcc gcggcccggg
    11221 ccgcagccgt ccgaccccgg gggccggggc gaaggtggcg gcgcgctcgc gggtgacgaa
    11281 gaaatcggtg acccgcgccc gcgccgcccg cggcagcagc ctggccagtt ccggcaggta
    11341 gcgcttgcgc agcacgtccg tgggcagctg gatctcctcg cccgcggccg actgggacag
    11401 cgcgaggtac tgcggccgcc cgggccccgg cgcgccgagc cccgagggac cgccgcggtc
    11461 gaagatccac tgcacggggc tgccgagcgc ggcgaggaac gggcggcgca ggacctgccg
    11521 gtcgtagacg acatggacgt tgaggatcgg cgcggtgccg atgtgccgca ggccgcccgg
    11581 gtcggtcatg gcgcccgccg gcagcaggcg ggcggcgacg tcgtggggcg cggccagcac
    11641 gacggagtcg gccgtcagct cgtgcgcggc ccccggcagg ccgcgcggcg cggcgacggt
    11701 gacgtgccag ccgccgccgc gggcgggggc gaggcggcgg gcgcgcgtgc tcagcagggt
    11761 cgtgacgccc gcccggtcca gggcggccct ggccctggtg tcgtgcagtt cgccgagcgg
    11821 tgcccgcggg atgccgaggt cggccgcgcc cggcgcggtg agcaggccgg tgcggaagac
    11881 catcgcggca agcccgagcg acacgtcgcc ggcgcgggcg ttgagggtcg cgacgccgat
    11941 gaggtcccac agcgcggcca cggcgcggtc ggtctggccg tgccggcgca gccaggccgc
    12001 gaagtcctgc cggtcgagcc gcgggtcgcc cgggtcgagg gcgcgcagcg cgagcgtggc
    12061 gcgggccgcg gcggcgcgtt cccccgggga gaggtgcggg tagcgggcga ggctgccggc
    12121 caggtgcagc ggaacgggca gcccggtgcg ccggatgcgg ccgaggcggc cggtggcggc
    12181 gtcgagcacg ggcacgtcga ggcgcggttg cagcggggcg agggcggcgg cccccacccg
    12241 ctggaggaag ccgcggtagg cggtgcagca gcgcaggtag acgtgctggc cgttgtcgac
    12301 ggtgagcggt ccggccggcg agtcgcggcg gaaggagaac gcgagcccgc ccagccgcgg
    12361 gcgggactcg accagggtga cggcccgccc ggcgtcggcg agcgcgagcg ccgcggtggt
    12421 accggcgagg ccgcccccga tcacgacggt gtgcccgggg cgccgcgtgc tggtcacagc
    12481 cgctcccgcc gggcggcgcg gcgtgcgtcg aggccggtga ggccgcgggc ggcgacgagt
    12541 gccttgtggc ccgcgggcag ggtgacgcgc ccgcgcagca cggcgcgcgg ctcggcctcg
    12601 atgcggtcga ggagccggtg gtagatgccg gccatggtgg tgacgcaggc gccggagcgg
    12661 cggtcgagca ggggcagcag ccgggagccc tggacgaaca gctcgcgggc cctgcggacc
    12721 tcgaagcgga tcagcccggt gaagtcggcg tcccggccgg gggcgaccac gtcgggcccc
    12781 tcggggcagc cgaacttccg caggtcctcg gccggcaggt agacgcgacc gcgctcggcg
    12841 tcctcgcgga cgtcgcgcag gatgttcgtg agctggaggg ccagtcccag ggtgtcggcg
    12901 tactcctcgg cgcgttccgt accgggcgcg ccgggccgga cgccgaacac gccaagggag
    12961 aggcggccga tggtgccggc cacgcgggtg cagtagaccc gcaggtcctc ccacgtctcg
    13021 taggtgtggc cgcgcacgtc catcaggacg ccgtcgatca gttcgtcgag tgcgtcgagc
    13081 gggatgggga agcggcgtcc cgcgtgtgcg agggcgaccg cgacggggtc ggtgtcgtcc
    13141 tcgggtaccg ccccgtcccg gacccgggcg agcatggcgc ggcccgcggc gagccgttcc
    13201 tccttggcct cgggtgccag gtcaccgtcg ccgatgtcgt cgacgcggcg ggcgaaggcg
    13261 tacaccgccg tgagggcccg ccgcttgggc gcgggcacga ggcgggcgcc gtagctgaag
    13321 ttccgcgcgt gctgctcggc gatgctctcg cagtaccggt aggcggcgac gacggcagga
    13381 ggcaggggtg aacgggtggt cacggcctcg aagctcacgt tcctcttcgc agtgtcgtgg
    13441 ccgccgcgta cagcagtccg cccttggacg cccgcggtgg cccggccagg acgtcgtacc
    13501 cggcgtcctc gatggcccgt gcggcggcgt ggccgccgcc gatgaatccg gcgagcagca
    13561 atcgcagccg cccggacact ccggacatca ggggcgcgcc ctcttcgagc agcctacgtg
    13621 cccggtcggt caggtatgcc accagggtgc gcacggaagc gttcgccgtg ggcgcggcga
    13681 ggtcggcttc ggtcacgaag aagcggtcca tgacctcggc gggaaggtag atccggtccc
    13741 tggcaaggtc ctccgcgacg tcctggaggt gctcgatcag ctggagcgcg gtgcacacgg
    13801 cgtcggagcg gcggacccgc tcgggggtgg cggtgccggt gacggccagc acgaggcggc
    13861 cgacggggtt ggcggagagt tcgcagtagc cgaggaggtc cgcgtacgtg gcgtagcggc
    13921 ggacgcgctg gtcgacgcgg ttggcctcga tgaggtcgag gaacgggcga ggggtgagtc
    13981 cggagcgccg cacggtgggg atcagctcgc gcagcagcgg gtgccggggc ggggtgccgc
    14041 cggtggcgct ggcgaagacg cggcggaggt cggcctcgac ggcgtcgagc aggagcaggc
    14101 ggtccacggc gcccgccggg tcgacgccca ggtgcgccgc gtcggcgccg cccggggcca
    14161 ggtcgccgtc gccgatgtcg tcgacgaggc gggcgaagcc gtagagggcc atcaggtcgt
    14221 cgcgccaggc cgccggcagg aagcggggcg ccacggggaa gttctcgtgc gcggccttgg
    14281 ccaggacggc tcggccgccg tccggccccg cgtcgctgtg ctcggccgtc agcacgggcg
    14341 gtccgtcgtc accattgccc tcatgcctac tcttttaccc tatggtcgga caatcgcccg
    14401 tgccggacac gcgttccggc acgggcggtg accgcgtgcc cggcctactt gccggtctct
    14461 tcctcgtacg ccttgagcac ctgatcggtg ggcccgtcca tcaccagctc gcccttctcc
    14521 agccacagca cccggtcgca ggtgtccctg atcgacttgt tgttgtggct gacgaggaag
    14581 acggtgccgg cctccgcgcg catctcgcgc accttggcct ccgagcgccg ctggaacttc
    14641 ttgtcgccgg tggccagcgc ctcgtcgatc atgagcacgt cgtgctcctt ggccacggcg
    14701 atggagaacc gcagcctggc ctgcatgccg gaggagtagg tgcgcatcgg caggctgatg
    14761 aagtcgccct tctcgttgat cccggagaag tcgacgatct cctggtagcg gcccttgatc
    14821 tcgtccctgg acatgcccat ggccaggccg ccgaggatga cgttgcgctc accggtgagg
    14881 tcgttcatca gagcggcgtt gacgccgagc aacgagggct gcccgtcggt gtagaccttg
    14941 ccgcgctcgg gcggcaggag gcccgcgatg gcgcgcagca gggtcgactt gcccgagccg
    15001 ttgctgccga tgaggccgat ggcctcgccg cggtaggcga cgaagctgac cccgcgcacc
    15061 gcgtgcacct cgcgcatctt gaagccgcgc tcgcggcgca ccatccggcg cagcgcggcg
    15121 gtggcggtgc cccggccgcc gccgccgtgg acgcggtaga cgatgtgcag cccgtcggcg
    15181 atgaccgtgg gcacgcgctg cccgcccggt cctccggtgg agatgtcctg ttcagccacg
    15241 accgtaccgc tcctccgcct tccagaagta cacgaagccg ccgatgccga cgacgagcgc
    15301 ccagccgagc ccgaagagcc aggtgaccgg ctcgacgctg tcgcggtagg cgccgtcgat
    15361 gagcgcgtag cgcaccaggt ccatgtacac ggccgccggg ttggccgcga ggacgtccgc
    15421 cagccaggcg ggcccctcgg cgcgctcctc caccatgtac tgaaggggga acatcactcc
    15481 ggaggcgtac atccaggtgc gcagcacgaa cggcatcagc tgggacaggt cgggggtcgc
    15541 gctgcccagc cgggcgaaga acagggccag gccggtgttg aagaccagtt gcagcagcag
    15601 cgcggggatg accagcagcc agttgaactc ggggaagtgc ccgaacgcga ccacgatggc
    15661 gaacaggatc accatcgaga acagcagctg ctggagctgc tggagggaca gggagatcgg
    15721 cagcgaggca cgcgggaagt gcagggcccg caccaggccc aggttgcccg agatcgactt
    15781 cacgcccgac atcaccgagt tctgcgtgaa ggtgaagacg aagaccccgg tcaccaggaa
    15841 ggggacgtac tcctcgttct ccatgttgcc gcgcccttgg agcagcagcc cgaagatcag
    15901 gtagtacacc agcgcgttga gcagcggggt gagcacctgc cagatctggc cgagcttggc
    15961 ctggctgtac tgggcggaca gtttcgcctg cgagaaggcg actatgaact gccgccgccc
    16021 ccacagctgc cgcacgtacc ccggcaggga gggccgggca ccactgacgg acaggccgtg
    16081 acgggccgcg agttcggcca gtggtacatc acgggggggc gcactgtcgt gcgtggtctc
    16141 actcacttga actctcgtcc tcgcagggca caagctggaa gatgccgcgg tgcggcggct
    16201 actggatgtt ctcagacccg agcttgtcag atgacaggag gtcgtccgag ccgggtcagg
    16261 cgccataccg tacgccaacg catcggcctg cggggcccgc agggcgtccg ccagccttcc
    16321 acgaagccgc cgaaccacgc ggcgagcgcc ggcctcgacg gcctgcgcag cagggtcagc
    16381 agcagccagt tcatgaggta gacgggcacc aggggcaggg gcaggttgcg gcgggccagc
    16441 cacacccggt tcctggcgat catccggtgg tacacggcgt gccgggacgg ggcggtcgcg
    16501 gggtggtgca gcacgaggtc ggcgcggtag tcgatgtgcc agccggcgtc gagcgcccgc
    16561 caggccaggt cggtttcctc gtgcgcgtag aagaagttgt ccggcaggcc cccgacctgc
    16621 tggaagacgt gggtgcgcac ggcgttcgcg cccccgagga aggtggtgac ccgcgaggag
    16681 cgcgacgggt cggaggcacg cagtcgcggc acgtgccggc gttgcgtggt accgctctcg
    16741 ggatcggtga tgcggaagct gacgatgccg agctggggat cggcctcgaa ggcggcccga
    16801 accgtttctg ccacgttttt gtctggaagt cgaccatcgt cgtccagaaa cagcagcacg
    16861 tcgacctcgc tgcccccggg gccgaacgcc tcgatgccga cgttgcgccc accgggaatg
    16921 ccgaggttcc gcggcagttc gagactgcgc acgccgggtg gcaggccggg cagccggacg
    16981 ccgttgccga cgacgaccac gtcgatggcc gtgccgtcct gcgcggccac cgagtcgagc
    17041 agcgcccgca gcgcctcggg ccggtcgccc atggtcagga tgaccgcgcc gagtctgagc
    17101 tgcgccgtac ccaccacact cacctcagcc tgctcgacgc caggacggac accaggtgca
    17161 ggagagtctg cacgagcgcg acggcggcca gcagggccac gccgaggcgg gtgaagaaca
    17221 ggtcatccct ggccaggtcg agtaccgcca ccaggaggat cagcagcgac gcctcgacgc
    17281 ccccgaccag ccggtggaat ttcagggccg cggcggctct gcgcgccagc gcgagccccg
    17341 aggagcgggg tatggccgcg tcgtcccggg ccgccgggag cccgccgcgg gtccgcgcta
    17401 catcgaccag gtcggtctcg gccttgatca ggatggcccc gagcgcggcg agcgtgccga
    17461 ggaacgccca gagccagttg ggggcggcct cctcggcggc gaacacgtcg gcggcacgca
    17521 ccccgaagcc caccaggagc gccgcctcgg ccaggtagtg gccgacccgg tccaggtaga
    17581 cgccggtgat ggaggtctgg ccgcgccagc gcgcgacctc gccgtcgacg cagtcgagca
    17641 ggaggtagag ctggatgagc agcgccgcgg ccacggcccc ggcgaggccg gggaccagca
    17701 gcgcggcgcc ggccgcgacg ccggcgagga ccatcaggta ggtgagctgg ttcgggctga
    17761 tccgggtgtt caccaggtgc cgggtccagc gcagcgagat ctcccgcatg tacaggcgcc
    17821 cggcccagtg ctcaccgctg cgccggtcct tcacccccgg ggggtgcacg accggccgga
    17881 gttcagctac cgatggtttt gacatagtcc gcgtacgcgt ccctgatctg gtcggttgac
    17941 aggtcgaggt gttcgaggat ggtgtagcgg ccgggcctgg tccgcggggc gaacgccacc
    18001 gcggccacga actcgtcggc gctgaatccg atgtggcccg gcagcacggg cagcccgtgg
    18061 cggcgcagcg tctcggcgat caggccgcac tggtcgacgg ccccgcgcag gtgcatcgcg
    18121 aacgcggccc cgagcccgac ctgctccccg tgcggcgccg aacgccgcgg gtggagtacg
    18181 tcgagcgcgt gcgagatctc gtggcaggcg ccggaggacg gccgggtgtg gccggcgatg
    18241 gacatggcga tgccggagag caccagcgcc tcggacagca cggtcaggaa cgcgtcgtcg
    18301 ccgcagtcgc ccgggtgtcg cagcacggcc tcgcccgcct gcctggccat ggcggcggcc
    18361 agcccgtcga tctgctcccc ggtctcgcgg tgggacaact cccagtcggc gatcgccgag
    18421 atgttggaca gggcgtcccc gatgccggac cgcacgtagc gcacgggcgc gcggcggatc
    18481 acgtcgaggt cgatgaccag ggcgatcggc gtgggcacac cgtaggagcc gcgtcctgcg
    18541 tcgttgtcga gcgtggacac cggggagcag atgccgtcgt gcgacaggtt ggtggccacg
    18601 gccaccatgg gcagcccgac ccgggcggcg gcgtacttcg ccgcgtcgat gatcttgccg
    18661 ccgcccagcc ccaccacggc gtcgtagtgg cccggtcgca tcgcgtcggc cagctgcacc
    18721 gcggcgtcga tggtgccccc ggcgacctcg taccagtcgg cgcccggcag ggccggggcc
    18781 agccggtcgc gcagggccgc gccggagccg ttgctgatcg cgacggcgag ccgccccgag
    18841 gaggagatcc gctggtcggc aagcaggccc gccaggttgt ccagggcccc cgccatgatg
    18901 tcgaccgaga cgggggacgg gatgaggcgg gtcagtaccg gcacgcgatc tcccgccctc
    18961 gcgcgaggtc gtcgtggttg tcgatttcga cccagctgac gtccccgatg gcggcggtgt
    19021 cgatgcggaa gccgcggtgg accagctcct ggtagccgtc ctcgtagtac agctgcgggt
    19081 cgcgttcgaa cgtggtgcgc agcgcgtcgg ccagcggggc cgcggccccc ggctcgatga
    19141 gcgtgacgcc gatgtactcg ccggtcgcct cggcggggtc catcagcttg gtgatgcgcc
    19201 gcacgccctt ctccgggtcg gcgacgacct tcatctcctc gtcggccagc ttcttcacgg
    19261 tgtcgagtgc caggatgacg cgccccgtcc ccgggccgcc cgccgcctgc gcggccagca
    19321 gggtgcgttc caccgacggg gggtggacgg tgtcgccgtt ggcgaggatc acgccctcct
    19381 cgatgacctc gcgggcgcac cacagggagt aggcgttgtt ccactcctcg gcccggtcgt
    19441 tgtcgatgag ggtcagccgc actccgtagc tgcgctccag ggcgtccttg cgctcgtaca
    19501 cggcctcctt ccggtagccg acgacgatgg ccgcctcggt gaggccgacc tcggcgaagt
    19561 tcgccagggt gaggtcgagg accgttctgc cgttctcgcc ttccgcgtcg atgaccggca
    19621 ccagtgcctt gggcagggtg tcggtgtagg ggcgaagacg ccgtccggcg ccggcggcca
    19681 gcacgaggcc gatcatgcgg gttctcctgt ttcgtcgtgt acggccggcg cctgggccga
    19741 gatccagaag cggatgctct cgccaagcac caggaacgcc gtggccccgc caaggaccgc
    19801 gagcgcgacg gtgaagccct gcccgccggc ccacagggcg gcggcggagg agaccaccag
    19861 gacccgcccc tcgtgcccgc cggtgaccag gaccagccgg cgggggggtg ccccggcgcc
    19921 gcccctgagg cggtacaccg tgtcgtagtg atggtaggcg caggcggcca ccaggcagaa
    19981 agccgccggc aacgctccgt ttacccccga ttccgccgcc agcacgagga ccgcgaggta
    20041 ctcgccgccg cggaacagcg gcggcagcac ccagtcgaac ggcctgacca gcggcgccgc
    20101 cgtcgcgcgc ccggcgcaca cggcgtaggc gacagccgcc gcgacggccg ccgagccgcc
    20161 ggccactccc ggcaccagca gcaggccgac gagcagcgcg gtgccggccg cggcccacag
    20221 cggcgcggtg agtgcgctgc ccgcggggcg cgggcggacg cgggccgcgg cctcggcgag
    20281 cgggccgttg tcggcgaggc cgccgagcgc ggcggccgtg ccgggcccgc cgccgggcag
    20341 gcggcgcgag cgcagcagcc ggcccgcggt ggtgtagcag gcggcgaggc cggccgccac
    20401 gagcaggacg acgaaggtcg cgcggggcgt ggtgaacgcg gtgagcaggg cgatcagcgc
    20461 ccagcgctca ccgatgggca gcacgatcac gcggcgcagc cagaccgtcc agccgatccg
    20521 gtcgaggcgc ccggacagcg cggtggcgcc ggccgcgccg ccgggtgcgg gcgggtgcgc
    20581 ctcgttgaac gcgaagtcca cgacgtgacg gcaggtctgg aggaccatgg cgccgagcgc
    20641 gagggcccac acgtcgtcgc ccccgcgggc ggcgccgagc gccaggccgg cgtagtaggc
    20701 gtattccttg gcccggtcga acgtggcgtc gagccacgcg ccgagcgtgg agtaccgcag
    20761 ggcgtagcgg gccagctggc cgtcggcgca gtcgaggacg aacgagagca gcagcagcag
    20821 gcccgcggcg acgaagccgc ccctggtccc ggtggcggcg cagccggcgg cgatcagggc
    20881 ggtgacgagc gaggccgtcg tgacctggtt cggcgtgagg ccgcggcggg cgcaccagcg
    20941 tgcgaggtgg cgggagtagg ggctcacgaa gtgggtggtg aagaagccgt ccctcgcctt
    21001 gaccgcggag cgcagccgca cggcctcctc gtcgacggcg gccatgtccg cctcggccct
    21061 ggcccgctgc tgcgtcgtcg tgggaacggc ggcgacgagg gtgccgagtt cgggccggtg
    21121 cggtggcgag cccgcggcgg tgaggcgtgc ggccagctcc tcgggaaggc aggtgccggc
    21181 cggcggcgcg gccacggcgc ggccgtgcgt tccggccggc ggccggggcg gcggggcggc
    21241 ctcggccgca gcggctgcca gggcggcccg cccctcgggg agcgcggtca cggcgcccgg
    21301 cagggccgcg accgcgaacc ggggatcggt gaggccgagg cggaggctgt gccggtggcc
    21361 gacgaagcgc gggtcgacga ccgcgacgcg gtggccgggc gggacggccg tgagctccgc
    21421 cgccaggccg gccgccgcgt ccagaaccag gacggagaag cccagctcgc gcaggtcgct
    21481 ttcgaggggc gacccgggcg ggggcggacc ggtgaggatg gcggtcgaca ggtgactcac
    21541 tccttggggc agaaccgtcg gcacggctgc acgtcggcag agattatctg atgaccacca
    21601 cacggacaga atggcgttga catcaagaaa ccctgagttc atgtccggcg ccccgcacgg
    21661 cggtcgtcgc gaccctatgt gacgccaccg gcacggtggg cgacaggggg gcgcgggggc
    21721 gggcgggccc gcgcccccgg cgtccgacgg gttcccccgg ggttagggtg ccctcatgag
    21781 ctggctgatc accgggggtg ccgggtacat cggggcacac gtcgtggaga ccatgcgcgc
    21841 cgcgggcgaa cgcgtggtgg tcctcgacga cctctcctcg ggccgcgccg gccggctgcc
    21901 ggccgacgtg ccgctggtgc gcggctcggt cctcgaccgg gacctgctcg acacggcgct
    21961 cgcggagcac ggggtgcgcg gggtggtgca cctggccgcg aagaagcagg tggccgagtc
    22021 ggtggccgag ccgctcgcgt actaccggtc caacgtgcac ggcctgaccg tcctgctcga
    22081 cgcggtcgtg gcggccgggg tgcgggagtt cgtcttctcc tcgtcggccg ccgtgtacgg
    22141 cacaccggag accggcacgg tcaccgagga cacgccctgc cgcccgctga gcccctacgg
    22201 ggagaccaag ctggccggcg agtggctggt gcgggccgcc gggcgggcgc acggcatcgc
    22261 gacggcgtgc ctgcgctact tcaacgtggc cggggcgacc cgccccgagc tggcggacgc
    22321 cggggcggcc aacgtcgtcc ccatgttctt cgaacggatc gcggccgggc ggcccccgga
    22381 gatcttcggc gccgactacc ccacgccgga cggcacctgc gtacgcgact acgtgcacgt
    22441 ggccgacctg gccgacgcgc atctgctcgc cgcccggcac ctgaccgaag ccgcgccggg
    22501 cgatgacctc acggtgaacg tcggcacggg ccgcggcgcc tcggtgcggg agctggccgc
    22561 cctcgtcgcg gacgtcaccg ggttcgccgg acccccgcgc gtcgccgacc ggcggccggg
    22621 ggacccggcg cgggtggtgg cctccgtcga actggctcgc gagcggcttg ggttcacggc
    22681 ccgccgcgga ctgcccgaca tggtctcctc ggcctgggag ggctggcgcc gcgcgcacgg
    22741 cggcctgtag ctccccacca ttgccgcacg tcggagcgcc cggcgcgcac ccggcgggcc
    22801 gggagaagaa tcagcaggtc agagcacatg acaacggtgt tcagtgccgc gttgccagat
    22861 acccccctcc cgtagttcac tgtggagtgc cgacgaaaca aggggggcgc ttcgatggga
    22921 gccggacacc accacggcgg gccgccgcag ggcggcaccg cgggcgcggc ccaccgcagg
    22981 cggctcaccg cggccctcgc catcgcctgc gtgctgctgg tggccgagct ggtgggcgcc
    23041 gcgctgaccg gctcgctcgc cctgctcgcc gacgccggtc acgtcgccac ggacgccgtc
    23101 ggcatcggga tggccctggt cgccatccac gtggccaacc ggccggtgcg cagcgaccgg
    23161 cggacgttcg gcttcgcccg cgtcgaggtc ctggcggccc tggcgaactg cgtgctcctg
    23221 ctgggcgtgg gcgggtacat cctggtcgag gccatcggcc ggctgcggga gccggccgag
    23281 gtgcccggcg ggctgacggt cgtgttcggt gtcgccggcc tgctgctcaa ctgcctgtcg
    23341 ctcgcactgc tgatgcgcgg ccagcgggag agcctgaatg tgcgcggcgc cttcctcgaa
    23401 gtggcggccg acgccctggg gtcggtcgcg gtggtggccg ccgccctcgt gatcatgttc
    23461 accggctggc aggccgcgga cccggtcgcc tccctgctga tcgccctcct gatcgtgccg
    23521 cgcgcggtca ggctggcacg cgaggcgatc gacgtgctcc tcgaaaccgc gccgaaggac
    23581 gtgcggatcg ccgaggtcag ggaccacgtg ctggggctcc ccggcgtcga gggcctgcac
    23641 gacctgcacg tgtggaccat cacctccggc atgcccgcgc tgtccgccca cgtcgtcgtg
    23701 gcgcgcgaga ccctggacgc ggtcggccac gaggagatgc tgcacgcgtt gcagggctgc
    23761 ctgggcgagc acttcgacgt ggcgcactgc acgttccagc tcgaaccctc ggggcacgcc
    23821 gcccatgagc ccggtctgtg ccactgaccc ggtgcggcag actggtcctc ggcccgcggt
    23881 ggcgggcaga gggtagggcc gcgaggccgg ggaacgacgg ccgcgaggcc ccgggagagg
    23941 tacgcatgcc gcagagcacc gacgccatgg cggatcaggt catgctcgaa ctcgtcgacg
    24001 aggacggcag gacggtgggg accgcggaga agctgtccgc gcaccaggcg ccgggaagac
    24061 tgcaccgtgc cttctccgtc ttcctgttcg acgccgcggg gcggctgctg ctccagcgcc
    24121 gcgcgctggg gaagtaccac tcccccggcg tctggtcgaa cacgtgctgc ggccacccgt
    24181 acccgggcga gccgccgttc ctggccgcca cgcggcgcac cgtcgaggag ttgggcgtgg
    24241 cgcccgcgct gctgcgcgag gccggcacgg tcacctacca ccatcccgat ccgcagtcgg
    24301 gtctggtcga gcgggagtac aaccacctgt tcgcc
//
