LOCUS       NZ_CP019779            21050 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Streptomyces sp. MOE7 chromosome, complete genome.
ACCESSION   NZ_CP019779
VERSION     NZ_CP019779.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MOE7
  ORGANISM  Streptomyces sp. MOE7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8399509)
  AUTHORS   Elnahas,M.O., De Leon,K.B., Amin,M.A., Hussein,M.M.D., Ali,A.E. and
            Wall,J.D.
  TITLE     Complete Genome Sequencing of Streptomyces sp. Strain MOE7, Which
            Produces an Extracellular Polysaccharide with Antioxidant and
            Antitumor Activities
  JOURNAL   Genome Announc 5 (22), e00442-17 (2017)
   PUBMED   28572320
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8399509)
  AUTHORS   Elnahas,M.O., De Leon,K.B., Amin,M.A., Hussein,M.M.D., Ali,A.E. and
            Wall,J.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2017) Biochemistry, University of Missouri
            Columbia, 117 Schweitzer Hall, Columbia, MO 65211, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 8.1
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002090335.1-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 02:19:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,435
            CDSs (total)                      :: 7,344
            Genes (coding)                    :: 7,005
            CDSs (with protein)               :: 7,005
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 230 of 339
            Pseudo Genes (incomplete)         :: 155 of 339
            Pseudo Genes (internal stop)      :: 7 of 339
            Pseudo Genes (multiple problems)  :: 47 of 339
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:50:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6542892
            Orig. end                         :: 6563942
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019779.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Judy D. Wall 117 Schweitzer
            Hall Columbia, MO USA 65202.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21050
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="17"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21050
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21050
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11050](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11050
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(149..163)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.48"
                     /tool="antismash"
     misc_feature    211..224
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(241..250)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.67"
                     /tool="antismash"
     misc_feature    complement(780..794)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.8"
                     /tool="antismash"
     misc_feature    787..802
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.95"
                     /tool="antismash"
     misc_feature    787..805
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.89"
                     /tool="antismash"
     misc_feature    805..819
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.3"
                     /tool="antismash"
     misc_feature    complement(1393..1407)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     misc_feature    complement(1688..1703)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.02"
                     /tool="antismash"
     misc_feature    2227..2241
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.37"
                     /tool="antismash"
     misc_feature    complement(2410..2425)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    complement(2909..2923)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.67"
                     /tool="antismash"
     misc_feature    complement(4589..4605)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.11"
                     /tool="antismash"
     misc_feature    6703..6718
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.86"
                     /tool="antismash"
     misc_feature    complement(7774..7787)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     misc_feature    complement(8205..8214)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(9440..9449)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            10001..11050
                     /locus_tag="STRMOE7_RS28880"
                     /old_locus_tag="STRMOE7_28870"
     CDS             10001..11050
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377851.1"
                     /locus_tag="STRMOE7_RS28880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_28870"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_084774485.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-61, bitscore:
                     207.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPATASQAAASQTLARCRALVQPALVEAVERLHPWLADMAAHSL
                     GWTGTHGSFVPGSQGKGVRQALTVLCAEAAGAPAECALAGAVTVELVHTFSLVHDDIMD
                     GDETRRQRASTWKAYGPGPAILAGDAMCALAAQVLCDSPAGQVGAAVRHLADALHDMAR
                     GQADDLCFEFRSWTGPDAVRVHEYRSMAEHKTGALLGCATGLGAVLAGAPAATVAGLTR
                     AGRHLGVAFQAVDDLLGIWGEPEDTGKPVYSDLRRLKKTYPVLAALATDTLAAGQLMGI
                     LESGGTLDDAGARQAADLIEEAGGRSATRREAQQHLDRAHDCLAALDLEPTACDEIQAL
                     LPSLIHRRA"
     gene            11311..14247
                     /locus_tag="STRMOE7_RS28885"
                     /old_locus_tag="STRMOE7_28875"
     CDS             11311..14247
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="STRMOE7_RS28885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_28875"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_084774487.1"
                     /transl_table=11
                     /translation="MTDAWVGTWEQDMGGLRIAALGPLRAWRGERQLDTGPAQQRAVLT
                     SLTLRCGQVASADELVRDVWGAEPPASAHVAVRNHVSRLRTVLESESAAPKALVSVAGG
                     YALHLPDGALDVSRAERLHARAQAARSQGDLEPAVRFLAEAEALWDGTPLTGVPGPYAQ
                     RQRERLIEYRLLLVEARLTLELQLGGHTRVVGELIALADEHPLREGLRALQMLALYRCG
                     RQADALAGYAEARRHLAAELGVDPGPELVRLHQRILEADPTLAPPPGVAAVSPAPGPAT
                     GADRPTWVPPAQVPPDAPDFTGRREESRQVRDALAGAVRADATAPVICVIHGMGGVGKT
                     TLAVHAAHAVREQFPDGQLYVDLRGTGREHANPYEVQEFFLRSLGVLAGNVPSGREERT
                     ALYRSRMADRRLLLLLDNAADTEQVSALLPGTAGSAALITSRTALMCLPATTHTALEPF
                     SEPEALALLERMAGSGRCRQEQQTARDLVRACGMLPLAVRVVGARLVVRPRWTLATLAE
                     RLSDRSQRLGELEAGSLAVESVFHLGYSTLDEAEARAFRLLAIPEVPDLSPAAAAAALN
                     CDRREAEALLESLAHQGLLEPGEPGRYRYHDLLRLFARHRTLDTDPSTTRQAALSRVAR
                     FYLTGTSSAMRAERPYSRLPDVADPDGMPGAAAFNDALHAQEWMLHELPAMLAVTGQIL
                     QHPYRPVSAEDTRTLSSLLALLMPFTDFCLPWDAIHQLAPTLLRAAEHHGERLATVFSC
                     VAAAVACARLGHHEEAAALAARAHEALDPGDRALAPRVVYTMGVVAGARPDGLDKAIGH
                     FRSAHALACESGEPGMAAQCSVSLAGAELALGRPHQALEAARDALAHCLPGDSPVGIAL
                     AQRVLGDALAELGRPGEAVTEYATALAVCRAHGLHAQRAHTLLSLASALAAVGRPEQAR
                     TCAAEGKAALAQLGDTAGEERARALMNRLAAAGPSGPPGNRTAAGRDH"
     gene            complement(14203..14535)
                     /locus_tag="STRMOE7_RS28890"
                     /old_locus_tag="STRMOE7_28880"
     CDS             complement(14203..14535)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STRMOE7_RS28890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STRMOE7_28880"
                     /product="hypothetical protein"
                     /protein_id="WP_084774488.1"
                     /transl_table=11
                     /translation="MNSLPPSRLLRGRWIPLALTVAVVSGCGLTGSPADFPTPSPPPSS
                     APPPLPPPDESVPDESVPERHCRERTRLPETVEVSWPGAAAVHRATGPDGTSVIPAGCR
                     PVPWRA"
     gene            complement(14532..14957)
                     /locus_tag="STRMOE7_RS28895"
                     /old_locus_tag="STRMOE7_28885"
     CDS             complement(14532..14957)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STRMOE7_RS28895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STRMOE7_28885"
                     /product="hypothetical protein"
                     /protein_id="WP_084774490.1"
                     /transl_table=11
                     /translation="MGFIKSTTVTQVAEAVGQSDPLARPVVTLGVGSGRHPFLWAMLSA
                     GIADSDTFFVTLTDRSVLFHEVTSAGYRPGKLRYDVAHEQVRARIGEVRRRFLWSTFRF
                     RFPGDTEAVWLNVKRAWRPEMDRFLAALRQDSPGRPS"
     gene            complement(15084..17978)
                     /locus_tag="STRMOE7_RS28900"
                     /old_locus_tag="STRMOE7_28890"
     CDS             complement(15084..17978)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="STRMOE7_RS28900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_28890"
                     /product="AAA family ATPase"
                     /protein_id="WP_084774492.1"
                     /transl_table=11
                     /translation="MPTNPAETAPHAERGAGGPVLIGRERELSALARLLEGPWTGGDSA
                     VISGGWGCGKTALLRAALADLRQDPGTCVVSAVADPLERDLPFGVVRRLFEHLGADDSS
                     GPPFRDRTPDAARVLTPGAQRPDGPASAVTGQGAEALGDLYRLCVRLAGDRRLLIAVDD
                     LQWADPHSLLWLRYLLRRADNLPLVVLATLGPGAAHPHAAAVAAVEPLFPHRLTLDGLA
                     DDAVEALATQVLGEAPERPFTVACREATGGNPLLLHAVLRGLRASGQRPRTELADRITG
                     HVPADLGSAVLTRMQEVDPHAVTTAQAVAVLGGAPGIDLITGVTGLPEPAVADAVHRLV
                     GTGWMTGTEDGLSFVCGILPAAVAAVVLPSRRRDLHLRAARHLLAHEAPLLRVAAHLLL
                     SPLGEPWVPEVLGRAATLAAEQGDDAHAAALLRRALREELTAELRATLLATLGELELTS
                     SLPVAVRNLERSLELSTDPTQQTAIARKLAGALLALDRHPDALETLRRTSEAVRRTDPD
                     QAMRLEIDFIHTSLSEATSAPAVVPRLMELDVSDAAGSPVQRPLAALLSLRAAMTGTST
                     REVVALARLALSQGMAPEDDESVVYTGAVTSLGAAGETELALAYADAAVRAAHPGISAF
                     HYAHALTTRANIHCRLGRLADCQADAEAALGALDRIGVGPCNGLSTFAITTLAETLLRQ
                     GKLADAEDLLVRGDLTGRLNGNWINDYVLMVRGWLRCAQGRLEEGLADFLLCGERTCAR
                     GMPNPGFFPWRSEAALVYAALRQGEAARALAEEELRLARIWGVPEVTGVAVRALGVVVG
                     GRKGLDLLGEAVRLLDGTPARVRYAQALADCGVLARKVGRLSEARAHLRQAVSVAHECT
                     ATSLADQALAELRAAGDRPRTRTFHGVGALTPTERRVADLAGRGLTNREIAQRLFVGLR
                     TVEVHLTNVYGKLAIDGRAGLTRALANHPSDQEL"
     misc_feature    complement(15087..15089)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18536..18970
                     /locus_tag="STRMOE7_RS28905"
                     /old_locus_tag="STRMOE7_28895"
     CDS             18536..18970
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003947386.1"
                     /locus_tag="STRMOE7_RS28905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_28895"
                     /product="DUF485 domain-containing protein"
                     /protein_id="WP_084774494.1"
                     /transl_table=11
                     /translation="MTTHASPPGSTTADAPGSTGTPPATDHLPATVFRTAQQGRPFGQL
                     RRSQRAFAAVATTAVLSVYLLYVLLSSYAPGLMAGKVVGNLNVALFLGLAQFAATFIAA
                     WLYTRHANRRRDPLAEQIKEGIEQARIRAHSHVATEGTAA"
     gene            18967..20595
                     /locus_tag="STRMOE7_RS28910"
                     /old_locus_tag="STRMOE7_28900"
     CDS             18967..20595
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573719.1"
                     /locus_tag="STRMOE7_RS28910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_28900"
                     /product="cation acetate symporter"
                     /protein_id="WP_084774496.1"
                     /transl_table=11
                     /translation="MITQLRQTALAAPGADGGRWLTIGLFLAVVAATLGVTLWASRQTK
                     GTTDFYTGGRSFSGFQNGLAISGDYMSAASFLGVTGTIALFGYDGFLYSVGFLVAWILA
                     LVLVAEPLRNAGRFTMADVLAFRLRQRPVRTAAGISTIVVSVVYLLAQMVGAGSLVALL
                     LGVSGDAPRRWIILGVGVLMILYVVVGGMKGTTWVQIVKAAMLMAGTLVLTVLVMSKFG
                     WNLSSLLGSAAEASGKGHAFLSPGLKYGAGPTTKLDFISLGVALVLGTAGLPHILVRFY
                     TVPTAKTARTSVNWAIGLIGVFYLMTLVLGFAAAALVGHSTIEAANPAGTTAAPMLAEA
                     LGGGPGSTLGATLLAVTSAIAFATILAVVAGLTLTSSASFAHDLYAHAVRKGKASEREE
                     IRTARFAAVGIGMVAVVLSMFADKLNTAALVALAFAIAASANLPTILYSLFWKRFNTTG
                     ALCSIYGGLVASVVLVIFSPVVSGTPASLVPGADFHWFPLENPGLVSIPIGFLSGWLGT
                     LASRETDPDKYAELEVRSLTGAGAH"
ORIGIN
        1 gttcaccagg aggttcgcga gtactacgag agtgtcctgg ctacggcttc gccggtgtcc
       61 gacgccgtac tcgtgcccaa gaaggtgcac ttcgtgtggt tcggcaagcc gatgagtcca
      121 catggcatgg ccaacgtgct gcgctgggcg gaccacatat tccgggccaa cgagaagttg
      181 cctccgggga gacagtggga gctgaacctg tggaccgacc ccaagttcaa cgccaagggg
      241 tcgaaaaacg cctggcagac ggcgacggag aggctgcgca aggctggtgt cacggtgcac
      301 accgacacgg ctgagaaagt ggcgggggcg gcgcgccgtg tgcaggagag ataccggcag
      361 ctcgatcccg atggcagtca aggactggcc gggctgcctg acctgggtca gatctaccga
      421 gccggattga agcagggcgc gttcaacctg ggctccgaca ttgctcggta cgcagtgctc
      481 gccgagcagg gaggggcgta cgcggatgtg gacctcggcc ccggccatgt gtcgtgggag
      541 accatgccgg agatccggat gcggcaggat gaggtgccgt tgctcagccc ggggttgcgt
      601 gacgggagct ccctgatgac ggagctgcga gctctgggcc ggcgagcgca gacgggttcg
      661 agtgattcag gcggaccggt cactccggaa gatctgctgg ccgcagcgga gagccgctat
      721 aagaagggtc acctgggcaa tcacttcatc gtcgcaccac cgaattccga cttcatcaat
      781 ctgctcaatg agaagattcc tcagaagttc caggaaatca gcgccagttc atcgaagaac
      841 ggccctgacc tgacccggga agccgcggcc atctccggtc cgggcctcat ccatttcgtc
      901 cgccagaatc agagcgggtc ggcactgggt gagtacgtgg gggacgtgct cggtctgtgg
      961 agggcggaac ccgccgcggt ctggcagacg ccgcccggac tccgcagccg agacctggtc
     1021 gctctcttcg atccgcaact cctcaggacc tgggcaggat tggagtgggt cacacaggag
     1081 agcagctatc aacttgatcc actgcgacag cctggctccg ctgacgctcc gatggcggca
     1141 ccatcgggcg cgctcccgat cggtgaccgc ggggtcgggg acagccagat catcgacagt
     1201 tggcgggccg agtcggcgct acctcgggtg cggcgctccg acgctctgcg gcgcatcgat
     1261 acggccgtcg aggagtggac gaacggcggc cggtggcggc ctggtgatca cgacaccaac
     1321 cagcggcagt tgggggccgt cctcgacgcc gtgaaagcgt ggcagttggg caagaacggc
     1381 tccagtggcc gtatcgaggc ggtcgatcgc ctcaccgcac acgtccagtc cgagttgcac
     1441 gctctacagc agcgcatcgc cgagcaggcg caggcggagg agccgtccgg ccaggagcac
     1501 ggcggcaccg acgtccgtcc gcacgccgtc ctcccggatt ccgaaggcgg ggcaccgtcc
     1561 cacgaggccg accgctggcc gacctctccc gcgccggagg gcgccgctcg ttccgcaccc
     1621 acgtcggggg agtctttccg tgcgatcggg gagatctcct tcgggcaggg ttcgaagcga
     1681 ccgggggaag accaactggc caagatcaag gacttctcgg attcggtcgc cgccgaagcg
     1741 gtgcgacggg tcacccacga cgagaagccg ctccgggttt acgtcgaggg aggcgggaac
     1801 ggcagcaaat tccagtcgat acgcggaaca tcgggcaatg ccgacgctgg gttggagcgt
     1861 gcccgggcgg tgtgggacga gctgcgcagc cgattgaacg aagagatctc ccggttgtgg
     1921 agcggagatc cggacattct gaccggcact tccctgctcc aggccccccg ctcccggggc
     1981 cagggcgagt ccaccgctcc gtttcccgag acgcccgtgg agtcgctgac ccccgcggag
     2041 gcccgcgcgg cccgtcgtac ggtccggatc tgggcggcgg acgacggacc cgcacgcgta
     2101 ctgcggttgc tggcgcacga cgggacgcaa ctcgacgtcg accggcgcca ggcgctcctc
     2161 gactacgtcg acgagtccgc caggcgtggc gaagaagcca gagtccgtct cctgctgcgc
     2221 cgattgaagc ttcagaacct tcacgtactg cgcgatgaac tcgactcgcg ctacgcggag
     2281 cgggttgccg agttcgctct gcccgccgat gcgctcactc cggtgcccaa ggacgttcac
     2341 ttcttctgga taggtgagga gcccagcgcg ggggcgttga acaaccttgc ggcgtgggca
     2401 cgatcggccg gggacaagtg gaaacagcac ctgtggaccg acgcgaccta cgaggggtgg
     2461 agcggccagg cgcgcgcccg tctcgagcag atcgtcaccg tccaccggga ttcgcttgag
     2521 gccctgcgca tcgcggaccg gccgcaagtg cttgaggtct acgagacggc tgtggcgaac
     2581 gaggcttaca acctcgcctc cgacatcgcg cgctacttga tccttgagcg gatgggcggc
     2641 gtctacgccg acgtggacct gcatccggga accgtggatc tgtcctcgat gccagagatc
     2701 accatgcgtg cggaggacct ccccctgctc gccccgcgcg tgcgggatat ggacagcgtc
     2761 gccaacgcgc tggccgcgcc gggggtggaa gctcccgccg gccggatgga gcaagtcgac
     2821 ctggcggcgc ggcttcggtg ggaggcggga gtcctcggca accacctcat cgtcgcacca
     2881 ccgggatcgg agttcatcac ctcgctcttg gacgtgattc ccaagaactt cgccgccctg
     2941 cgggagcaca tggcggcggc cttcgcggat gcgtcgaagc tccccgagga gctcaagaac
     3001 ctggcaccgc agatcagtgg ccccgccatg atccaggacc ggatccccgg tagcgaaggc
     3061 ttccctccgc ttcaacgatt cgccatgaag gcgggtgcgg aaggtgttgc tgagttcgat
     3121 ggttcctcct atccgacatt ccagcggaat gaggccatag cgctgttctc cccccgcgcg
     3181 ctggaggctt tccggggaat ccgctgggtc actgcggaca gcgagcgcca gctggacgga
     3241 ccggcggtcc aggaaccggc ggcagaaccg tcggtcagca tggcgccgct acacctgccc
     3301 gaagccccgt ccgacgcccc ggcgccgact catccggccc gccgggtgcc ccgtcccgcc
     3361 gacccgtcga cctgggtgga gcgtcggaag gaggcgccgg tggggcatgt cgggcgtctg
     3421 cacgccgaga ggttcgcccc ggccgtcgac gccatgagtc gccaccgtgc tcccggcacg
     3481 ctggccggcg cacagaccct gatgcgcgcc gaggtctccc gcatccaggc cgaaaacggc
     3541 acatgggtgc gcgaccacac cgtgatgctc cccgtccgcc tcgccggcac cggcttgtcc
     3601 gagcacgacc tggccggcct tcagacaggc atccaagggg cgttggacga gcacatcaac
     3661 gcagtcggct acgcgctgcc gcgttccggt gaccagttcc atgtcgggct gcggctggtt
     3721 catgacgatg atcaccccga gcatgtgatc gtgagccggt ccgacaagcc tggtcgttcc
     3781 gaccagcggc actggaacct cggcccgccc accgaggacc agaagtacct cccggtggtg
     3841 ttccacgagg tcctccacta cctgggcctg cccgacgagt accgggactt ggcgtttctc
     3901 ttccgtcgga acgcggacag cgcggccgtc cacaccgatg gcttgatggc cggcaccacg
     3961 cgcctggcgc cgctgccaga gcgctatttg gccgccatcg aggacaccgt cgacgccggc
     4021 gttgttctgc acggctacgc actgcgggat ctgaccgccg accgtgacgg gccgggggcc
     4081 ggggcctcct cgcatcacga cggatggctg agcgccgtgg accgggaggg cgaacgatgg
     4141 gataccgcac cttcgccgcg gccggacgga gcggacacca cccacgcggc agcttcctca
     4201 gcgcgagccg cagacgaccg cctcgacacc caccctgcct ccgcccctgc ctttgcccgc
     4261 gagcaggctc ctgaggatgt cgcgttgccg cccagtccga cggaggccga agggccgccg
     4321 tcgaccggta ccggtacgga actccggccg cacgaagtcc ccctgccgga ccgcccctcc
     4381 gagtccaccc gcacctcccg ttccgacggc gagtcgatgc acacggccga cagcgccccc
     4441 ggtccggtcg cgcggccgcc ggagccccgc catccctggt acgtcgacca cggtgcccac
     4501 ggcgggatcg aggtcgccgg tgcggccacc tgggatcggg cgcgggtgga gaccgaggcc
     4561 gccgccgtcg cgggggcact caccggtctg cccggttcac cggcacacca gaaggaactg
     4621 cgagccggca tcgagcggga gttgcgcgag ctgttcgccg ccgaccgcgg tgaacggtgg
     4681 agtgagcggc tgcgcgcggg gcgcatggcc gaggtcgccg gtcagacggt gtggctgcgg
     4741 ccggcgttgc gtgaggtgac cccggccgag ggaccgcagc atcctgacgg cgccgtgcag
     4801 caccaggtct actacggctc cgccaaggtg agcagcggtg ccgagcggga gacgcggagc
     4861 gcgctgaacg ccgcgttgac caccgtgctc acggtgggcg ccacggggct gtccgcggtg
     4921 gcgggcccgg gcccgcagct gtcgatgggc ggcaccacca aacgcagcca caccgacggg
     4981 ttcgaggtgg tctccgggcg cacgccgaag accaccggct ccacggactt cgtcgctcag
     5041 ctgcacgtcg aggtgtcggt ggacggtgag gtcgcccccc acgacctcgt gaccccgcgt
     5101 ggtctgaccg tgcgcttccc cgaggtgttc tcctcggccc aggagccccg gcccgacgcc
     5161 gtcgcccacc cgatgcgccc ggtctccccg gacgcccaac acctgacccg ggcaccgctg
     5221 acccttcagg ccatcgacac cggccctgta gtggtcggcc tcgtccgcga gctgcgccgg
     5281 gcgggcatcc cggcggacac ggtcgccgtc ctgatgccca agttcatcaa ggagttggcc
     5341 ggtgaggaga tcgttcgtac ccgcagtcgc ttctggctga ccaccggcga ctcctccggt
     5401 ctgttcgacg agagcacctc cgtgatgagg cgtttcacgg gccgcttcac cgcgagcacg
     5461 gtctgggagc gtgcgcagta cgtcggtacc acggcggtga agatccaaga ggatctgggg
     5521 ctggtcacca acgacaagca cggccgggca acgaccggcg agggccgtat cggcggtggc
     5581 atcgacgtac tcggcatgag tgcgacggac aacggtcatc tgggcaacct gtccgtgggc
     5641 gcgtcggccg agtcctcccg cacggtctct ctcggggtca acagcagccg ggcggagtac
     5701 acggtgctga cccggcacga ggaccatgcg cgctaccacg ttcaggcccg ggtggaggtg
     5761 gtcacgcact ccgagacgca ccgggacgtg cgtccggtgc aggcgaccgt ggcgaccgag
     5821 atccttgtgc cgctgagggc ggctgccgag ttcgagcggc ggatgttcgg cgaggtggtg
     5881 accgaggcgc tgcggcccgg ggaacccggt acccagcctg tgggtgtgga ggcgatcgcg
     5941 cccccgcagc tggcctccgg tcggggccag gggttcggca agctcatcgg cctgcccggg
     6001 tcggagcggg tgtacggcga actgcaccgg caactcgact cgatgatgac ggagctgcgt
     6061 cgccggccct ctccggccga ccggtcggga ctggaggcgc tcctcaccgc gtactacggc
     6121 cgccccgcgc tggaaggcga cctcggggtg gtgctcgccg gactggacca gcggctgacg
     6181 atcggcgggg agcgcttcga cgtgtccgcc aggctccatc tgcgcgaccg gctggagggc
     6241 accgagtcgt atgtgatgac ggtggacggg aaggcggtca gccgcgcggg gatgcaggcg
     6301 caacgctcgc acggagtcgc cctgtccgcc tcggccaacg ccagtgccca gctgaaggtg
     6361 tcggatcggt tcaaggcacg ggtgggcaag ttccaggtcg gcggcagctg gaacagggcg
     6421 acgagcaaca cgctgtcggc cgagaccaag aaccaccgcc gtacccagac caccggcctc
     6481 gttcatgaac tcgcctacga cgcggtgtgg gaggtcagcg tccaccaccc gaaggccgac
     6541 gcccactggt ggatcgagga ccggggcaat atggcggcgg tcttcgccgt cccggaggag
     6601 cacacccccg cccacgacac ccccgcccgc gccgccgacc tgtcgccctc tcccgaccct
     6661 gccccggccc cggccgatga gggctacggc gccgtgcgca cgctgaccga ctggccggcc
     6721 gccgcccata tccccttcga gcaccactcg ggggcggtgt acccggtgtt cctgcacacc
     6781 gacgagctgc tgcatgccgc cgtggagcag taccgacggg tcaacggcat cctgccgggt
     6841 gcgctccgcg agcgctggga ggtcccgctc gaactgcgcc acagcatgaa cagctccgcg
     6901 ttgcacctgg agttcgacgc actggcctca ccggacggct ggcatgtgca actggacccg
     6961 cacaagaact ggaagcaggc gctgcggctg cgcctgcggg cgtacgaccc cgtccaccgc
     7021 ggtcggcccg atgtctcgat cgagcgggct ctccaggtca gggaccgcac cacggagagc
     7081 tctcgttccg ggtacgggtg gcacctgacc gggcagctcg gcgtgcacgt ccgccatgac
     7141 acccaggagg tgctggcgag cgtgatcgcg agcggatcgg cgtcgaggca acagcagcac
     7201 gaggcgcagc acggcgccgg cggcgtcacc cgggccggct acgcggggcc ggtgcacgcc
     7261 taccgctcgg acgtcgtggt ggaggtcacc gcgatccggt ggaagggcgg gaccaccgag
     7321 tccgcgacca cctacctgca cctcgcccag ggaatggaca gtctggtacc gcaccggctc
     7381 gtcagcgacc tgggacttgc ggtgcccgag cacgtccagg cacgtatgga cgaggacgac
     7441 aagacccccg ccccccggcg cggtccccat cgcctgttgg acgacggtgt caccgaggtg
     7501 cccctacgcc gttacacgga gcgcacgttg ggcgtactga ccgggcacgt cgaacagctc
     7561 catggcgccg gcgtcctcgc ccacatcgaa caggtgctgc gggagcgcgg gctgctgccc
     7621 cgcgacgccg tgccgcgccc caatctgcgg atgcaggcac tgcgccaccg cttctccgag
     7681 gaggctctgg ccggcaacct cccggcgctg ctgggcaatg gtgtccacgc ctggatgccg
     7741 atcacgggcg ccttcggcca gacccacttc gtctcgatcc gggtcaccgc gaaggcgttc
     7801 gaggcggtcg agcactggac gcgccccgag acgaccctcc tgttgggcgg cgagaggtcc
     7861 accgcgctca gcgagaagca ggtcgccgca accgagcgga aggtcaccgg ggaggccgag
     7921 ggccgcggga gcctcggctc ggtcaagttc agcggcggcg gcgaggcggg atggctgagc
     7981 aagtcctcgg acacccggtg gatcagcaag aacaccaagg acgtcttccg ggtcaaaacc
     8041 gctgaaggct cacaggagtt cactcatccc ttgcgctacc gggtcgagat caacggggcc
     8101 gcccaggggc cccacgtggt gcactggctg ggtacccggg tcaaagacgg cgtactgacg
     8161 ctgggcagcc tgtcctcccg gttcctcggc accggaaacg aggtggccgc cttctggtac
     8221 agccaccagg tgggctcgtg gagcagtgac agcgcggccg agggcaaggt gatcgacggc
     8281 agcgtgcgga ccctggtgcc cgaccacctc acctcggtgc agccgcgggc ccatgtcgac
     8341 ccggaagtcc cactgatcga tcgccggcac actctcggta agggcgtcca ctggcacacc
     8401 ggtgcccggc cggcgcccgg gccggtggag accgaactcg cggcgcacct cctcccgaag
     8461 gcggtcccgg cgagcgaagc ggtggcccgg tgggccgcgc tgaccacgct gccgccgcgg
     8521 cagcggcccg cggacccggg ggccggggac gcctggcagg tgccgggcct ggggctggac
     8581 agcaagcacg gcatgcggct gcggttgtcc gcgaccgacg gggtgctgcg cgcccactcc
     8641 ggcgaactgc tggggcacac ctaccggttg ccgttgcgcg acggcggctc ggtcacggtc
     8701 ggcctgcggg tggtgcgggc gcagcaggtg gctgaggcac agttcaagga ccgttcctac
     8761 tccgaggcgg aggaactgcc gctcgcggtg cgcacccgcg cccgggggtg ggacgtggcc
     8821 ggccgctcct acgccagcgg cccggggacc gacgggaccg aactgcgcgg ctcgggtggg
     8881 ctgtcctacg gccgggtgca cggcaccagc gaggaggacg agacgcggct ggactacgac
     8941 aacaattccg tcacctcccg cgagctgcgt tactacggct tcgacgtgga ggcgttcctc
     9001 atcggaccgt acgggacgct ggcgatggag gtcccggagg gcctgtacgg gatgctgccg
     9061 accgacgtcg cggagggcct gcacaccgcg catccggacc tcttccacgg cccggcgccc
     9121 accgccgagg ccaagggcaa gacgcccgag gccgaagccc tggacgacct catggctggt
     9181 tgggagccgc cggccgccgg gagcagcacc gcgcccgtcc gccacctcgc cgacaggctg
     9241 cgggacgccg gcctcgtcga gggcagctcg cccctccggc tccgggccgg ggacaccgcc
     9301 caccccgttg acctggcgcg ggcggcggcc gagagccttg gcaggccgat cgacctcatc
     9361 ctggacagcg ggatcgaaca gcgcgtcgtg cccggcggca cggaccgttc ggcggcggcg
     9421 accccggccg gttccgtggg gccgccttcc ggcacggcgc aggacacgga tccggcccgg
     9481 tccgaggccg gtgcgcccgc gccagtggtc accgaggtct cggcgccgga aaccgacccg
     9541 ccgcctctcg gtgcgttgcc ttcttaatcc ttcggtatcg cccgtcatcc ctcgtggcct
     9601 gttctccacc taatgtggcc gcacaagggt tgcgctcgct gcccggtgcg gccaccgccg
     9661 ggcccggctt cgcacaggta ccgccggccg ggatcgccgc cgctgttgcc gagggcccgg
     9721 tgccggacgg catccgctcc gtacggagcc gccgatgtcc tcgtggcacg gacgaaggac
     9781 caccccgtgg ctccgccggc gggaccgcgt cgcggacagg acgagacccg ccggacacgc
     9841 acctgccgtg ccacgacgtg gccggtgtgc gaggcccgtt cccggccgcg cgcgggaggc
     9901 ccgaacgggc tccccttgtc tgcggaccgc cacgtcgtag ccgccggacg gccacgtgga
     9961 cgtgcaccgg aatcgcccac acgaaaggac acacccgatc atgacgcctg ctaccgcgtc
    10021 ccaggccgcc gcgtcgcaga ccctggcgcg ctgccgcgcg ttggtgcaac cggcgcttgt
    10081 ggaggccgtg gagcgcctcc acccgtggct ggccgacatg gcagcccact ctctcgggtg
    10141 gaccgggacg cacggcagct tcgtccccgg ctcccagggc aagggggtgc gccaggcgct
    10201 cacggtgctc tgcgccgagg ccgccggagc gcccgcggaa tgcgccctcg ccggtgccgt
    10261 caccgtggag ttggtgcaca ccttctccct cgtgcacgac gacatcatgg acggcgacga
    10321 gacccgtcgg cagcgcgcga gcacctggaa ggcatatggc cccgggcccg cgatcctggc
    10381 cggtgacgcg atgtgcgccc tcgccgccca agtcctctgc gactcccctg cgggacaggt
    10441 cggagcagcg gtgcggcacc tggcggatgc cttgcacgac atggcgcgcg gtcaggctga
    10501 cgacctctgc ttcgagttcc gctcatggac gggcccggac gcggtccggg tgcacgagta
    10561 ccggtcgatg gccgagcaca agacgggtgc tctgctcggg tgtgccaccg ggctgggcgc
    10621 cgtgctcgcc ggcgcaccgg ccgcgaccgt cgcagggctc acgcgggccg gccggcatct
    10681 cggggtggcc ttccaagccg ttgacgacct cttgggcatc tggggagaac cggaagacac
    10741 cggcaaaccg gtatacagcg atctgcgacg gctgaagaag acctacccgg tgctggcggc
    10801 gctggccacg gacaccctgg ccgcagggca gctcatgggg atactcgaat cgggcgggac
    10861 actggacgac gccggcgccc gtcaggccgc cgatctcatc gaggaggcgg gcgggcgctc
    10921 cgccacccgg cgcgaagccc aacagcacct cgacagggcc cacgactgcc tggcagcgct
    10981 cgacctggag ccgacggcct gcgacgagat ccaggcactg ctgccttccc tcatccatcg
    11041 cagagcgtga cggggacgcg gaacgcggtg gtgacgtgcg ggtgtgcgcc aacgggcagc
    11101 gggcgtcgcc cacctcggcg accgccgacg ggcgcccgtg cgggagggcc gtcccgccgc
    11161 ggcgggaggc cggagtgtcc gccgccatgt atcgaacagt ggacactccg gccgtcgcct
    11221 gcgcttccgg cgataatgac taccgggcgt cacttcccgg caggtgcccg cccctcggtt
    11281 cgcagcccac gaccgatgac aggttgatcg atgactgatg cgtgggtcgg gacgtgggag
    11341 caggacatgg ggggactgcg gatcgcggcg ctgggtccgc tgagggcatg gcgcggtgag
    11401 cggcaactgg acaccggacc ggcacagcag cgcgcggtgc tcacctcact gaccttgcgg
    11461 tgcggccagg tcgcgtccgc ggacgagctg gtgcgggacg tctggggagc ggagccgccg
    11521 gccagcgcgc acgtcgcggt gcgcaaccac gtctcacgcc tgcgcaccgt gctggagagc
    11581 gagtccgccg cgcccaaggc cctggtctcc gtcgccggcg gctatgcgct gcacctgccg
    11641 gacggggcgc tggacgtctc ccgggccgaa cggctccatg cccgggcgca ggcggcccgg
    11701 agccaggggg atctggagcc ggccgtccgc ttcctggccg aggccgaggc gctgtgggac
    11761 ggcactccgc tgacgggagt gcccggcccc tacgcccagc ggcagcggga gcgcctcatc
    11821 gagtaccggc tcctcctcgt cgaggcgagg ctgaccctgg agctccagct cggcggacac
    11881 acccgggtcg tcggggagct gatcgcgctg gccgacgaac atccgctgcg cgaggggctg
    11941 cgtgcgctgc agatgctcgc gctgtaccgc tgcggccggc aggcggacgc gctggccggg
    12001 tacgcggagg ccagacggca cctcgccgcg gagctgggcg tggatcccgg ccccgagctg
    12061 gtacgtctgc accagcgcat cctggaagcg gatccgacgc tggcaccgcc gccgggcgtg
    12121 gccgccgtgt ccccggcacc cggcccggcc accggggccg accggccgac ctgggtgccg
    12181 ccggcgcagg tccctccgga cgcccccgac ttcaccggcc gcagggagga gagccggcaa
    12241 gtgcgcgacg ccctggccgg tgccgtacgg gcggacgcga ccgctccggt gatctgcgtg
    12301 atccacggca tgggaggggt ggggaagacc acgctggccg tgcacgccgc gcacgccgtg
    12361 cgggagcagt tccccgacgg ccagctctac gtcgacctgc gcggaacggg acgggagcac
    12421 gcgaatcctt atgaggtgca ggagttcttc ctgcgctcct tgggagtcct ggccggcaat
    12481 gtgcccagtg ggcgggagga gcgcaccgcg ctctaccgtt cgcggatggc cgaccgccgg
    12541 ctgctgctcc tgctggacaa cgccgccgac accgagcagg tgagcgccct gctgccgggt
    12601 accgccggga gcgccgcgct gatcaccagc cgtacggcgc tgatgtgcct cccggcgacc
    12661 acccacaccg cgctcgaacc gttcagtgag ccggaggccc ttgccctcct ggagcggatg
    12721 gccggcagcg ggcggtgccg tcaggagcag cagaccgccc gcgacctggt gcgggcgtgc
    12781 ggcatgctgc cgctggccgt ccgggtcgtc ggcgcccgtc tggtggtccg gccgcgctgg
    12841 acgctcgcga cactggccga gcggctcagc gaccgctcgc agcggctggg tgagttggag
    12901 gccggcagcc tggccgtcga atcggtcttc cacctcggct actcgacgct ggacgaggcg
    12961 gaggcgcgtg ccttccggct gctggccatc cccgaggtgc ccgacctctc cccggccgcc
    13021 gcggcggcgg cgctgaactg cgaccggcgg gaggccgagg cgctcctgga gtccctggcc
    13081 caccagggcc tgctggaacc cggggaaccc ggccggtacc gctaccacga tctgctgcgg
    13141 ctgttcgccc gccaccggac cctggacacc gacccctcca ccacccggca ggcggccctg
    13201 agccgggtcg cccgcttcta cctcaccggg acgagcagcg ccatgcgggc cgagcggccc
    13261 tacagccggc tgcccgacgt cgccgatccg gacggcatgc cgggcgccgc ggccttcaac
    13321 gacgcgctcc acgcgcagga atggatgttg cacgagctcc ccgcgatgct ggccgtcacc
    13381 ggccagatcc tccagcatcc ctatcggccg gtgagcgcgg aggacacccg caccctgtcg
    13441 tccctgctgg cgctgctcat gccgttcacc gacttctgtc tgccgtggga cgccatccat
    13501 cagctggccc ctacgctgct gcgcgccgcc gaacaccacg gggagcggct cgcgaccgtc
    13561 ttcagctgcg tcgcggcggc cgtcgcctgc gcgcggctcg gacaccacga ggaggcggcc
    13621 gcgctggccg cccgcgccca cgaggcgctc gaccccgggg accgggcgct ggcgccacgt
    13681 gtggtgtaca ccatgggggt ggtcgccggg gcgcggccgg acggtctgga caaggccatc
    13741 ggccacttcc ggagcgcgca cgccctggcg tgcgagagcg gcgagcccgg tatggccgcc
    13801 cagtgctccg tcagcctcgc cggcgccgag ctcgcgctcg gccggccaca ccaggcgctg
    13861 gaggccgccc gggacgccct cgcccactgc ctgcccggcg acagtccggt gggcatcgcc
    13921 ctggctcaac gcgtgttggg cgacgcactg gcggaactcg gccggcctgg cgaagcggtg
    13981 acggagtacg ccacggcact cgccgtctgc cgcgcgcacg gactgcacgc acagcgcgcc
    14041 catacgctgc tgtccctcgc ctcggcgctg gccgccgtcg gccggccgga gcaggcccgt
    14101 acgtgtgcgg cggagggcaa ggccgccctg gctcagctcg gcgacaccgc gggtgaggag
    14161 cgggcgcgcg ccctcatgaa ccgcctcgcg gcggccggcc cgtcaggccc gccagggaac
    14221 cggacggcag ccggccggga tcactgacgt tccgtccgga ccggtggccc ggtgcacggc
    14281 ggccgcgccg ggccagctca cctcgacggt ctccggcaac cgggtgcgct cccggcagtg
    14341 ccgctccggc acgctctcgt ccggcacgct ctcgtccggc ggagggagcg gcggcggtgc
    14401 gctgctcggc ggggggctcg gggtcgggaa gtcggccgga ctgccggtca ggccgcagcc
    14461 gctgaccacg gccacggtca gggccagggg tatccatcgg ccacggagca gccgggaggg
    14521 gggaagtgaa ttcatgacgg gcgccccggg ctgtcctgcc ggagcgcggc gaggaaccgg
    14581 tccatctccg gtcgccaggc gcgtttgaca ttgagccaga ccgcctcggt gtccccgggg
    14641 aaccgaaacc ggaaggtact ccacaggaag cgtcggcgga cctcgccgat ccgcgcgcgg
    14701 acctgctcgt gcgcgacgtc gtaccgcagc ttccccggcc ggtatcccgc cgatgtcacc
    14761 tcgtggaaca gcacggaccg gtcggtgagg gtgacgaaga aggtgtcact gtcggcgata
    14821 ccggcggaca gcatcgccca caggaacgga tggcgccccg accccacgcc cagggtcacc
    14881 accgggcggg cgagcgggtc ggactgccct acggcctcgg cgacttgggt cacggtggtg
    14941 gatttgatga accccatggg tctctcctcg atagggatga acgtgaaagg cggggaggta
    15001 atgaaggggg taccggtgcg cacgatggcg tcgcggtcgg caccgacgtc atttcgggac
    15061 ggtggaggac agctgatgtg ccgtcataac tcctgatccg aagggtggtt cgccagcgcg
    15121 cgggtcagcc ccgcacggcc gtcgatggcg agcttcccgt agacgttggt cagatgcacc
    15181 tccacggtgc gcagaccgac gaagaggcgc tgggcgatct cgcggttggt caggccccgg
    15241 ccggcgaggt ccgccacccg ccgctccgtg ggggtcagtg ctcccacgcc gtggaacgtc
    15301 cgggtgcgcg gccggtcacc agcggcacgc agctccgcga gcgcctgatc ggccagcgac
    15361 gtcgccgtgc actcatgggc gacactcacg gcctgccgca ggtgcgcacg cgcctcggac
    15421 agccggccga ccttgcgggc gaggacaccg cagtcggcca gcgcctgggc ataccgcacc
    15481 cgcgcgggcg tgccgtcgag gagccgtacg gcctcgccga gcagatcgag tcccttgcgt
    15541 ccgccgacca ccacgcccag ggcgcgcacg gccacaccgg tcacctcggg cacaccccag
    15601 atgcgggcaa gccgcagctc ctcctccgcg agcgccctgg ccgcctcgcc ctgccgcagc
    15661 gccgcgtaca ccaaagcggc ctccgaacgc cacggaaaga aaccggggtt gggcatcccg
    15721 cgagcgcagg tccgctcacc gcacagcagg aagtcggcca gcccttcctc cagccgcccc
    15781 tgggcgcagc gcagccagcc acgcaccatc aggacgtagt cgttgatcca gttgccgttc
    15841 agccgcccgg tcaggtcgcc gcgtaccagc aggtcctcgg cgtcggcgag cttgccctgc
    15901 cggagcagcg tctcggccag cgtcgtgatc gcgaacgtgc tgaggccgtt gcacgggccg
    15961 acgccgatac ggtcgagtgc tcccagcgcg gcctccgcgt cggcctggca gtccgcgaga
    16021 cggccgagcc ggcagtggat gttcgcccgg gtggtgaggg cgtgggcgta gtggaaggcc
    16081 gagatcccgg ggtgcgccgc ccgcacggcc gcgtcggcgt acgccagcgc cagttccgtc
    16141 tccccggcgg ccccgaggga ggtgaccgcg ccggtgtaga cgacggactc gtcgtcctcc
    16201 ggggccatgc cctggctcag cgccagccgg gccagggcca ccacttcccg cgtggacgtt
    16261 cccgtcatgg ccgcacgcag gctcaacagg gccgccaggg gacgctgcac agggctcccg
    16321 gccgcgtcgg agacgtccag ctccatcagc cggggcacca cggccggggc cgaagtcgcc
    16381 tcgctcaggc tggtgtgaat gaagtcgatc tccagccgca tcgcctggtc ggggtccgtc
    16441 cgccggactg cctcgctggt gcgtcgcaac gtctccagcg cgtcggggtg ccggtcgaga
    16501 gccagcagcg cgccggccag cttgcgggcg atggcggtct gttgcgtcgg gtccgtggac
    16561 agttccaggc tgcgctccag attgcggacg gcgaccggga ggctggaggt gagttccagt
    16621 tcgccgagcg tcgccagcag ggtggcccgc agttctgctg tgagttcctc gcgcagggcg
    16681 cggcgcaaaa gggcggcggc gtgcgcgtcg tcgccctgct ccgcggccag cgtcgccgcc
    16741 cggccgagca cctccggcac ccacggctcg cccagcgggc tgagcagcag atgagctgcc
    16801 acccgcagca gcggagcctc gtgggccagc aggtgccggg ccgcccgcag gtggaggtcc
    16861 ctccgccggc tcggcagcac caccgcggcg accgccgccg gcaggatgcc gcagacgaag
    16921 gagaggccgt cctccgtccc ggtcatccac cccgtgccca ccagccggtg cacggcgtcc
    16981 gcgacggccg gctccggcag gccggtgacc cccgtgatca ggtcgatgcc tggcgcaccc
    17041 ccgagcaccg cgacggcctg ggcggtggtc acggcatgcg gatcgacctc ctgcatccgg
    17101 gtgagcacgg ccgatcccag gtcggccggt acatggccgg tgatccggtc cgccagttcc
    17161 gtccgagggc gctgcccgga agcccggagc ccgcgcagca cggcgtgcag cagcaggggg
    17221 ttgccgccgg tggcctcccg gcaggcgacg gtgaacggcc gctccggggc ctcacccaga
    17281 acctgggtcg ccagggcctc gacggcgtcg tcggcgaggc cgtcgagcgt cagccggtgc
    17341 gggaacagcg gctcgacggc ggccacggca gcagcgtgcg gatgcgcggc ccccggaccg
    17401 agcgtggcga ggacgaccag cggcaggttg tccgccctgc gcagcaggta ccgcaaccag
    17461 aggagggagt gcggatcggc ccactgcaga tcgtcgacgg caatcaacag ccgccggtca
    17521 cccgccagtc ggacgcacag ccggtacagg tcgccgaggg cctccgcgcc ctgcccggtc
    17581 accgcggacg ccggcccgtc cggccgctgc gccccggggg tgagcacccg ggcggcgtcc
    17641 ggagtccggt cgcggaacgg cggccccgac gagtcgtccg cgcccaggtg ctcgaagagc
    17701 cggcggacca cgccgaacgg caggtcgcgc tccagcgggt ccgcgaccgc cgagacgacg
    17761 caggttccgg gatcctgacg gaggtccgcc agagcggccc gcagcagtgc ggtcttcccg
    17821 cacccccaac ccccgctgat gacagcggag tcaccgccgg tccaggggcc ttcgagcagc
    17881 cgggcgagcg cgctcagctc gcgctcccgc ccgatcagca ccggcccgcc cgcgccccgt
    17941 tccgcgtggg gagcggtctc tgcggggttg gtcggcatgt cacaccacga ctgtctggag
    18001 ggcggccccg tcacggcgga cgggggcacg ctgtcttacc tggctgtgga gctgccggcc
    18061 tcacctgcga catgaagggc tgatgggggg agacccacat gcgccggggc cggcagctct
    18121 gaccggaagg gtggcgtcgg cgtgtaagga atcaataatt ttcccgtaag gggcccggga
    18181 cggcgcgcac aaggggccgg aggacggctc agaacgggcc gcggccgcga gatctttcgg
    18241 tgcgctaccc cgtacagcgg tcccttaatc cttcggtacg gcccgtcatc catcgtggcc
    18301 ggtcccgccc cacactttgg ctgaacaagg gtcatgcgac cgggtgccgt gcggcaccgc
    18361 gcggctgttc aggagccggc tcacgccgtc ccgtactccg caccgacccg agtcctcctg
    18421 ccgctcaccg accggcgggg gagcccgttc accgtcgccg tgaaccggtg agcaccaccg
    18481 tcccgtggcc ggtccggctg ccgggccaca ccgagtccca ccactggaaa ggcccatgac
    18541 cacgcacgcc tcccctcccg gcagcaccac ggccgacgcg cccggcagca cgggaacccc
    18601 gcccgccacg gaccacctcc ccgccacggt gttccggacg gcgcaacagg gccggccgtt
    18661 cggccaactc cgccgctcgc agcgggcgtt cgccgcggtg gcgaccaccg cggtgctcag
    18721 cgtctatctg ctgtacgtcc tgctgtccag ctacgcgccc ggcctcatgg ccggcaaggt
    18781 cgtcggcaat ctgaacgtcg cgctcttcct cggactcgcc cagttcgccg cgaccttcat
    18841 cgccgcgtgg ctctacacgc ggcatgcgaa ccgccggcgg gacccgctcg cggaacagat
    18901 caaggaaggc atcgagcagg cccggatccg tgcgcacagc cacgtcgcca cggaggggac
    18961 cgcggcatga tcactcaact gcgacagacc gccctggccg ccccgggcgc ggacggcggc
    19021 cgctggctga cgatcggcct gttcctggcc gtggtggcgg ccacgctggg cgtcaccctg
    19081 tgggcgagcc ggcagaccaa gggcaccacg gacttctaca ccggcggccg ctcgttctca
    19141 ggattccaga acggcctggc catctccggc gactacatgt cggccgcctc gttcctgggc
    19201 gtcaccggca ccatcgcgct cttcgggtac gacgggttcc tgtactccgt cggcttcctc
    19261 gtcgcctgga tcctggcgct ggtcctggtg gccgaacccc tgcgcaacgc gggccggttc
    19321 accatggcgg acgtcctcgc gttccgtctg cgtcagcggc cggtgcgtac cgccgcgggc
    19381 atctccacca tcgtggtctc cgtggtctac ctcctcgccc agatggtcgg cgcgggttcc
    19441 ctggtggccc tgctgctcgg cgtctccggt gacgcgccca ggaggtggat catcctgggc
    19501 gtcggcgtac tgatgatcct ctacgtcgtc gtgggcggca tgaagggcac cacctgggtg
    19561 cagatcgtca aggccgcgat gctgatggcc ggaacgctgg tgctgaccgt tctggtgatg
    19621 agcaagttcg gctggaacct ctcctcgctc ctcggctcgg cggccgaagc cagcggcaag
    19681 ggccatgcct tcctctcgcc cggcctgaag tacggcgccg gccccaccac caagctggac
    19741 ttcatcagtc tcggtgtcgc gctggtcctg ggcaccgcgg gcctgccgca catcctcgtc
    19801 cgtttctaca ccgtgccgac cgccaagacc gcccggacct cggtgaactg ggcgatcggc
    19861 ctcatcggcg tcttttacct gatgacgctc gtgctgggct tcgccgcggc ggcgctggtg
    19921 gggcactcga cgatcgaggc cgctaacccg gcgggcacca cggccgcgcc gatgctggcc
    19981 gaagcgctcg gcggcggccc cggctccacc ctgggcgcca ccctgctggc ggtgacctcc
    20041 gcaatcgcct tcgccacgat cctggcggtg gtggccggac tcaccctcac ctcgtccgcc
    20101 tccttcgccc acgacctgta cgcccacgcc gtgcgcaagg ggaaggcgag cgagcgcgag
    20161 gagatcagaa cggcgcggtt cgccgcggtc gggatcggca tggtggccgt cgtactgagc
    20221 atgttcgccg acaagctcaa caccgcggcg ctggtggcac tggccttcgc catcgcggcc
    20281 tcggccaatc tgccgacgat cctgtacagc ctgttctgga agcggttcaa caccaccggc
    20341 gcgttgtgca gcatctacgg cggcctggtg gcctcggtgg tgctggtgat cttctccccg
    20401 gtcgtctccg gcaccccggc ctcgctggtg cccggtgcgg acttccactg gttcccactg
    20461 gagaaccccg gcctggtctc catcccgatc ggcttcctgt ccggctggct gggcaccctc
    20521 gcctcccgcg agaccgaccc ggacaagtac gcggagctgg aagtccgttc cctcaccggt
    20581 gccggcgcgc actgacccct agggggtgtc tccccctggc tccgcgacgc cgtcgccacc
    20641 gcagcacacc acgtggtcct cacccgacca acgactccaa ggaacagcac gtcgtgaaca
    20701 acgaaagcct ggcgaacctc ctccatgagg accggcggtt cgccccgccg gccgacctgg
    20761 cggcgcatgc caacgtcacc gccgacacct acgagaaggc cgccgccgac cggctcggct
    20821 tctgggcgga acaggcccgc cgactcagct gggaggtgcc gccgaccgag acgctggact
    20881 ggtccgaccc gcccttcgcc tcctggttcg ctgacggcca cctcaacgtc gcctacaact
    20941 gcgtggaccg gcatgtggag aacggcctgg gcgaccgggt cgccctccac ttcgagggcg
    21001 agccgggcga cagccgcacg atcacgtacg ccgagctgca gcgcgaggtc
//
