LOCUS       NZ_CP019779            22238 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Streptomyces sp. MOE7 chromosome, complete genome.
ACCESSION   NZ_CP019779
VERSION     NZ_CP019779.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MOE7
  ORGANISM  Streptomyces sp. MOE7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8399509)
  AUTHORS   Elnahas,M.O., De Leon,K.B., Amin,M.A., Hussein,M.M.D., Ali,A.E. and
            Wall,J.D.
  TITLE     Complete Genome Sequencing of Streptomyces sp. Strain MOE7, Which
            Produces an Extracellular Polysaccharide with Antioxidant and
            Antitumor Activities
  JOURNAL   Genome Announc 5 (22), e00442-17 (2017)
   PUBMED   28572320
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8399509)
  AUTHORS   Elnahas,M.O., De Leon,K.B., Amin,M.A., Hussein,M.M.D., Ali,A.E. and
            Wall,J.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2017) Biochemistry, University of Missouri
            Columbia, 117 Schweitzer Hall, Columbia, MO 65211, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 8.1
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002090335.1-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 02:19:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,435
            CDSs (total)                      :: 7,344
            Genes (coding)                    :: 7,005
            CDSs (with protein)               :: 7,005
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 230 of 339
            Pseudo Genes (incomplete)         :: 155 of 339
            Pseudo Genes (internal stop)      :: 7 of 339
            Pseudo Genes (multiple problems)  :: 47 of 339
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:50:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4742115
            Orig. end                         :: 4764353
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019779.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Judy D. Wall 117 Schweitzer
            Hall Columbia, MO USA 65202.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22238
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="13"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22238
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22238
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12238](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12238
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    147..160
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.48"
                     /tool="antismash"
     misc_feature    complement(182..195)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.6"
                     /tool="antismash"
     gene            224..799
                     /locus_tag="STRMOE7_RS21140"
                     /old_locus_tag="STRMOE7_21090"
     CDS             224..799
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020556212.1"
                     /locus_tag="STRMOE7_RS21140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21090"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_084772501.1"
                     /transl_table=11
                     /translation="MDQEEARTRILDAAERLFYARGVQAVGMDELRTTAGVSLKRLYQC
                     FPAKDDLVEAYLRRRDTRWRAALAEYVEGRAAGSGERPLAVFDWLHDWFAEPDFRGCAF
                     LNSFGELGATSDGVGRVAREHKRALLAYLTGLVRALPVDGPDAVAGQLALLVDGAITTA
                     ALTGDPAAARHARTAAGSLLAAAGAREA"
     gene            complement(862..1389)
                     /locus_tag="STRMOE7_RS40095"
                     /old_locus_tag="STRMOE7_21095"
     CDS             complement(862..1389)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020622.4"
                     /locus_tag="STRMOE7_RS40095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21095"
                     /product="phospholipase"
                     /protein_id="WP_237323684.1"
                     /transl_table=11
                     /translation="MSLAGAALSGVLALSAATPALAGPAHPDGSTVRTSSATADHQAAA
                     ISKAQKLKRLNQLTEKYAMPLWENTRIKWQDGHDAYRFDWGTDGCSHVSDNPGGFHFWE
                     SCARHDFGYRNYKKMHEFTRAHKKRVDDSFLEDMQNQCKRQWGPYTELQRKGCLKVAKK
                     YYEAVRTLGHLQ"
     misc_feature    complement(1397..1412)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     gene            complement(1712..2947)
                     /gene="rocD"
                     /locus_tag="STRMOE7_RS21150"
                     /old_locus_tag="STRMOE7_21100"
     CDS             complement(1712..2947)
                     /EC_number="2.6.1.13"
                     /GO_function="GO:0004587 - ornithine aminotransferase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (37-357). E-value: 1.6e-100.
                     Score: 328.4. Matches aSDomain:
                     nrpspksdomains_STRMOE7_RS21150_Aminotran_3.1"
                     /codon_start=1
                     /gene="rocD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089890.1"
                     /locus_tag="STRMOE7_RS21150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21100"
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="WP_084772505.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.3e-113, bitscore:
                     378.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTRTAVVGAPRSSAELIQAEAPVLAHNYHPLPVVVARAEGVW
                     VEDVEGRRYLDMLAGYSALNFGHRHPDLIEAAHRQLDQLTLTSRAFHNDRLAGFAEGLA
                     ALTGLDMVLPMNTGAEAVESGIKVARKWAYDVKGVPADKATIVVAGGNFHGRTTTIVGF
                     SDDDTARVGFGPFAPGFRTVPYNDLAALEAAVDETTAAVLIEPIQGEAGVLIPDDGYLT
                     GVRELTRRAGCLFIADEIQSGLGRTGTTLAVEHESVVPDVLLLGKALGGGIVPVSAVVA
                     RRDVLGVLGPGQHGSTFGGNPLAAAVGSAVIDLLATGEFQRRAAERGEQLRAGLTALTG
                     KGVTGFRARGLWAGVDVDPALGTGREISERLLKEGVLVKDTHGSTIRLAPPLTITEEEL
                     ASALASLERVLG"
     aSDomain        complement(1877..2836)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STRMOE7_RS21150_Aminotran_3.1"
                     /evalue="1.60E-100"
                     /label="STRMOE7_RS21150_Aminotran_3.1"
                     /locus_tag="STRMOE7_RS21150"
                     /protein_end="357"
                     /protein_start="37"
                     /score="328.4"
                     /tool="antismash"
                     /translation="VARAEGVWVEDVEGRRYLDMLAGYSALNFGHRHPDLIEAAHRQLD
                     QLTLTSRAFHNDRLAGFAEGLAALTGLDMVLPMNTGAEAVESGIKVARKWAYDVKGVPA
                     DKATIVVAGGNFHGRTTTIVGFSDDDTARVGFGPFAPGFRTVPYNDLAALEAAVDETTA
                     AVLIEPIQGEAGVLIPDDGYLTGVRELTRRAGCLFIADEIQSGLGRTGTTLAVEHESVV
                     PDVLLLGKALGGGIVPVSAVVARRDVLGVLGPGQHGSTFGGNPLAAAVGSAVIDLLATG
                     EFQRRAAERGEQLRAGLTALTGKGVTGFRARGLWAGVDV"
     gene            complement(2944..3756)
                     /gene="ddaH"
                     /locus_tag="STRMOE7_RS21155"
                     /old_locus_tag="STRMOE7_21105"
     CDS             complement(2944..3756)
                     /EC_number="3.5.3.18"
                     /GO_function="GO:0016403 - dimethylargininase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ddaH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662066.1"
                     /locus_tag="STRMOE7_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21105"
                     /product="dimethylargininase"
                     /protein_id="WP_084772507.1"
                     /transl_table=11
                     /translation="MPTSRVASPRRYLVCEPRHFEVRYAINPWMRAEVPVDTARAARQW
                     STLIDTYRAHGHAVESVPPVPGLPDMVFAANCAVVMRGRVFGSLFHAPERRPESTAYET
                     WFKAAGFDVYRPESVCEGEGDLVPAGRFLLAGTGFRTARAAHHEAQEFFGVPTIGLQLV
                     DPHFYHLDTALFALDEENVAYFPDAFSPGCREVLARLFPDAVLATREDAMAFGLNSVSD
                     GRHVFIAPQATGLIDQLTARGYVPVPVDLSEFHKAGGGIKCCTQEIRS"
     gene            complement(3926..4432)
                     /locus_tag="STRMOE7_RS21160"
                     /old_locus_tag="STRMOE7_21110"
     CDS             complement(3926..4432)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559331.1"
                     /locus_tag="STRMOE7_RS21160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21110"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_084772509.1"
                     /transl_table=11
                     /translation="MTHKAVPFDELDRKIVKALIDNGRASFAEIGASVGLSSTAVKRRV
                     DRLRETNVITGFTATVRPAALGWLTEAYVEVYCDSAAPPRRLAEVVRNHPEIAAAMTVT
                     GGADALLHVRATDVEHFEEVLERIRAEPFIRKTISYMVLSHLLPESPEAGARRSATGNG
                     AGKQR"
     misc_feature    4434..4448
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.29"
                     /tool="antismash"
     gene            4638..5450
                     /locus_tag="STRMOE7_RS21165"
                     /old_locus_tag="STRMOE7_21115"
     CDS             4638..5450
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020120575.1"
                     /locus_tag="STRMOE7_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21115"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_237323685.1"
                     /transl_table=11
                     /translation="MRHATVRDDGAGDGLTRADRARRVAHVLRGQVLRGAFADGVLPDE
                     RALVAEFGTSRNTVREALGLLRDEGLVARRRGVGTVVVGRAYQHPLGELSGLAEVLQRH
                     GTVVNEVREARSVRPPLTVARRLGLAEGTPAVYLERLRRVDGLPLSLDCTYLIREVGEP
                     LLARGRETLERQDVFDLIERVAGAPLGRAEVSVQAVVADPATCAVLAMPEGGAVLAVER
                     LTRLADGRPADLEFIHLRGDRLTLHATLDRATGATSGRGGGRSRGGHR"
     gene            complement(5344..6063)
                     /locus_tag="STRMOE7_RS37750"
     CDS             complement(5344..6063)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STRMOE7_RS37750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="DUF3995 domain-containing protein"
                     /protein_id="WP_148666660.1"
                     /transl_table=11
                     /translation="MQSEPGKTLLRWAYAAVAWLVVSFVWHVQMGVMYEATMGPDDGTP
                     LWLFVSYDALIVLMSVVGVVCVLATVKPWGRRAPHWLVRAPLWIGCAVLTMRGVPGLVE
                     NVTTATGLTPHGLLGMEKEAVDTGSWDFWKTMVINGYFFLGAVLLVPATVLSRRSRRTA
                     KATRTTSAASAGGTAHPNRVRQPPYPTAAPPPTLPGTAASPVIDAHPATARRRARSSRP
                     LPGRGWRAGSAGPRADG"
     gene            complement(6325..7611)
                     /locus_tag="STRMOE7_RS21180"
                     /old_locus_tag="STRMOE7_21130"
     CDS             complement(6325..7611)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467918.1"
                     /locus_tag="STRMOE7_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21130"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_237323978.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 8.4e-43, bitscore:
                     145.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVPELLLLPDGPARGRAVLVDGGKFRAVGPAEQLIAAHRDLRPV
                     RLDGHLLMPGFVDAHHHLTQSFGKAQSFGQPSEIFKTVWEPLEHALDEESAYVSAKLAA
                     LEALRGGFTTVADAGTRAPVDVRALAKGTEEAGIRCVLGKIVSSGSGGPEHLGRWEGHP
                     LIHPSLAIAVPEDASADVIRKTADLCAEAGAVLQVHVNEHLASVERSLKSTGRRPLEYL
                     HHIGALGPHTLGAHATLLTPSETRLLADSGAAISYNPVASAWKGNGVAHATLLAAMGVR
                     FGMGTDGTRGDGFRMIDAGETAQRLAYGMAAGDSVCGAGRTWLEHATSGSADALGLGGV
                     TGEIAAGKAADFLVVNLEVPELTPSYDLRWELVRLANRDQIAAVVVGGKLRLWHGWPTD
                     WDGPALVARAAKLGPEVVRRAKLQRVEPV"
     misc_feature    7858..7871
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.12"
                     /tool="antismash"
     misc_feature    7858..7872
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.09"
                     /tool="antismash"
     misc_feature    7877..7889
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.54"
                     /tool="antismash"
     misc_feature    complement(7972..7989)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.84"
                     /tool="antismash"
     gene            8123..9022
                     /locus_tag="STRMOE7_RS21185"
                     /old_locus_tag="STRMOE7_21135"
     CDS             8123..9022
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089893.1"
                     /locus_tag="STRMOE7_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21135"
                     /product="hypothetical protein"
                     /protein_id="WP_084772519.1"
                     /sec_met_domain="RimK (E-value: 8.4e-08, bitscore: 30.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLCFLVEEQYRYDGMPLDVIRQLTAWGHQVDVLWPGRSLLPLSE
                     AVRAGSHDAWVLKTVSGGPGLTLLEAAAAVGLTTVNDVRAIRGVRDKALAAVIARGSGL
                     PVPVTYAAARAEEFAQIPEAEFPLVVKPADGSSGRAVRLVETPDRLPAAGTAEPAEPGG
                     AAGGLLIAQPYVPNSGTDLKVYCVAGELYATERRSPLHPGHPVRERQVPLTAEVARITA
                     EIGAVFGLDLYGVDVLLGPDGPVVVDINDFPSFRQVPDAVARVSSAVLRLARKGAEPAV
                     PGPAAPAEPPLAAIGGDR"
     gene            9019..9846
                     /locus_tag="STRMOE7_RS21190"
                     /old_locus_tag="STRMOE7_21140"
     CDS             9019..9846
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057092.1"
                     /locus_tag="STRMOE7_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21140"
                     /product="alpha-L-glutamate ligase"
                     /protein_id="WP_084772520.1"
                     /sec_met_domain="RimK (E-value: 2e-08, bitscore: 32.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGLITADAAHPVLAATGALLVGQGHRVEVVDPGGVPEGPGPLA
                     DVYLLKARTPRALALAARLEERGAAVINSAAATARCQDRVAMAELARGAGLPFARTRFV
                     GTPAELAAAGEPAGPLVVKSRHSRRGDLVARADSAVRLRELAAEWPEEPVVVQDFLAGS
                     GWDHKVWVVDGRLFAGLRRSELAPEGRGETLPLPPGELPADWRALALGVGEVFGLEVYG
                     VDLLDAGGGAPLLVDVNAFPGIRGQAGAPEALAELALRTGARAGRRASENGPE"
     gene            10001..12238
                     /locus_tag="STRMOE7_RS21195"
                     /old_locus_tag="STRMOE7_21145"
     CDS             10001..12238
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604221.1"
                     /locus_tag="STRMOE7_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21145"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_084772522.1"
                     /sec_met_domain="T1TS (E-value: 1.4e-84, bitscore: 283.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKPFELPDFYTPYPARLNPHLEAARTHSRKWARGMGMLEGSGIW
                     EQRDLDAHDYALLCAYTHPDCDAAALSLVTDWYVWVFFFDDHFLEKFKRTLDRAGGKEY
                     LDRLPAFMPLDLGAPVPEPTNPVEAGLADLWARTVPHMSADWRRRFAESTEHLLNESLW
                     ELSNININRVPNPVEYIEMRRKVGGAPWSAGLVEYATGAEVPARVAGSRPLRVLRDTFS
                     DAVHLRNDLFSYQRETEEEGELSNGVLVLETFLDCTTQEAADAVNDLITSRLQQFENTV
                     VAELPPLFLEKGLDPKSCADVLAYAKGLQDWQSGGHEWHMRSSRYMNDGGAAAGAAPPW
                     SPFSAGGLGTSATDLKKALATAGAHRVRSHTHVPHQQVGPSRIPDFCMPFPLTLSPHLE
                     GARRRVIDWADRMGLLQPQPGVPLSDVWDEAAMARHDLALCAAGIHPDATPEQLDLDSA
                     WLAWGTYADDYYPQVFGRTRDAAAAYACTERLKLFMPLDPATTPPEPVNAMERALADLW
                     PRTTRPMTPEARRAFRAAVDTMTASWLWEIDNQIQNRIPDPVDYIEMRRATFGSDLTMA
                     LSRLGHGRHVPPEVYRTGTLRSLENAAADYAALMNDVFSYQKEIEYEGEVHNGILVVQT
                     FFDCDYPTALAIVNDLMTSRMREFQHVAAKELPVVYDDFQLPAEARATLDGYVRELENW
                     MAGILNWHQGCRRYIEPELRHPVGSPGRLGAPSGLGTSAARFFQRAAAGAG"
     misc_feature    12465..12479
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    12465..12479
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.01"
                     /tool="antismash"
     gene            12767..13375
                     /locus_tag="STRMOE7_RS37755"
     CDS             12767..13375
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STRMOE7_RS37755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_148666661.1"
                     /transl_table=11
                     /translation="MATVRAGSSARFARYGSLQLDPASAPAPSYPSESRDPGDSRDPGD
                     YQDPSDSRDPGDSRDPGDYRDPSDRRDSGDSRDPGDYNDPSDSRDPGRDRDTGDSRDPR
                     DSDDYLDPGDARDTGDAPDRRDPQDPARSSDPGDPSTLPAPAGASDPVNSPGAAVPRRV
                     ARPSSSSPTKSSARPGRVARPSSSSPTKSSARPKVIKRS"
     gene            complement(<13321..>13440)
                     /locus_tag="STRMOE7_RS39210"
                     /pseudo=""
     CDS             complement(<13321..13440)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645507.1"
                     /locus_tag="STRMOE7_RS39210"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="F420-dependent methylene-tetrahydromethanopterin
                     reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRVWRAAGVGTVRLYPAGGTLQERLITLGRALDLVGELD"
     gene            13537..14313
                     /locus_tag="STRMOE7_RS21205"
                     /old_locus_tag="STRMOE7_21155"
     CDS             13537..14313
                     /GO_function="GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089904.1"
                     /locus_tag="STRMOE7_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21155"
                     /product="DNA-formamidopyrimidine glycosylase family
                     protein"
                     /protein_id="WP_084772526.1"
                     /transl_table=11
                     /translation="MPELPDVEAFRRTFVRCAQRRVVQHIEIHDAGVLHGLSGRQLRHE
                     LEGRRFAEPERHGKWLIARTGGPILLLHFGMTGRLVCTAPEEAAHPHDRVVFTMSREHR
                     LRYRDQRKLQGLWLVDEAGLDRVLGRLGPDAATVPRDAFRAALAARRGRLKALLMDQSV
                     LAGLGNLLVDEILWRTRLPPSRPARDLTDEEGDRLHTELRRTLRAAVRAGCVPPRDTWL
                     TGRRDDPDPHCPRCGGPLRRGRVAGRGTVWCPRCQP"
     gene            complement(14382..15428)
                     /locus_tag="STRMOE7_RS21210"
                     /old_locus_tag="STRMOE7_21160"
     CDS             complement(14382..15428)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074899.1"
                     /locus_tag="STRMOE7_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21160"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_084772528.1"
                     /transl_table=11
                     /translation="MRDAATTGVPVLDDVDRGIVHALHLDGRAPFSRIAEVLGVSTQTV
                     ARRYRRLRADAGLRVVGLADPHRAGRAQWLVRLTAAPHSAQDLARALARRTDTSWVKLA
                     SGGTEILAVVHTPADGTGGHALLLHDIPRTAGITAVSAHCLLHTYLGGPTAWRGRAGTL
                     DEDQQRRLAPPGAGPHDGQLAEAGRVLTEADHALLAALERDGRTGQADLAAATGWSPAT
                     VARRLAALRAAGALFFDVEADDALFGATTQAMLWMTVSPTHLDRVATALAGHHELAFVA
                     ATTGRTNVVAHALCPDPAALHRYLTRRLGGLRAIHTLETAPVLRTVKGAGPLAPAAAPR
                     PSPRAARR"
     gene            15641..17155
                     /locus_tag="STRMOE7_RS21215"
                     /old_locus_tag="STRMOE7_21165"
     CDS             15641..17155
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983670.1"
                     /locus_tag="STRMOE7_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21165"
                     /product="MFS transporter"
                     /protein_id="WP_272898519.1"
                     /transl_table=11
                     /translation="MPQPLPHPLPPVRPMPYPRRWCALAVLLVAEAMNLLDSTIMTVAA
                     PVIHADLGGPASGIQWFSAAYTLPFAVLLITGGRLGDIAGRKRVFRAGVAAFVLASALC
                     ALAASPTMLITARAVQGAAAALVIPQTIGLIRGMFHGDELARAMGSIGPVMGLAAVCGP
                     VLAGVLTHADLFGSSWRAVFLVNVPLGLGVLAAAPLLREDRSERRPRLDLTGTVLAVLA
                     TGALVHPLIGSGPDRGSPGRWVLFAAGLCLMALFGAHQRRRTARGRSALVETRLFSDRG
                     FPAALAAAVLFFAVVNGLMLVVVLQLQLGPHTDVRSAGLTLLPWSAAMVVASWTAGARL
                     VPRHGSRVMFAGLAALLLGTLGALVVYATGRPAAYPWPLLAALTAAGLGQGLFSVPFFT
                     TALGRVRPHETGSAAGLLNAAQQLGGTLGVALLGTVFLHTAPGAGAPGARAALLGARDA
                     CGAAVALLAGTVAAAVLLHAAARTRPASPRRDRRVRNAKSPSGYGR"
     misc_feature    complement(17252..17266)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.5"
                     /tool="antismash"
     misc_feature    complement(17261..17275)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.88"
                     /tool="antismash"
     gene            17370..17510
                     /locus_tag="STRMOE7_RS38025"
     CDS             17370..17510
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STRMOE7_RS38025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158541813.1"
                     /transl_table=11
                     /translation="MSFRKVFPRRRRDDGWGYDHDHGRRRRRYRRRFGRRRRRFFGYDN
                     Y"
     gene            17710..19557
                     /locus_tag="STRMOE7_RS21220"
                     /old_locus_tag="STRMOE7_21170"
     CDS             17710..19557
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604213.1"
                     /locus_tag="STRMOE7_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21170"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_107487420.1"
                     /transl_table=11
                     /translation="MWSLQTDLTIRTRRVGLKESLRRFWPLTHGDRRWIVLICLAAVAA
                     ALAETVAILLFAQLTDKALQKGSVSAFWVPAAMWLGVAVVGAVVGYLGNSLGAWTAERF
                     VMRLRARVFAHLQTLPPHFFQRSRRGDLVERLTGDVDAIEQMVITGLVQVAAALFGIIF
                     YAGAALWLRWDLALATFVLAPLFWTATRRFTGRVKEVSRRERAADGAITSVVEEGLVNV
                     VLTQAYNRQRDEEERLDRQARKWFRASVTSARLNGLYDQVVELLETFCVLAIIGLGAWE
                     ISAGRMTLGQLLAFAAFVGYLYPPIRSLGQLGLTATEATAGAERLLEILDARPAVSDPA
                     PSLVAPPRYRRALGEVEARHVHFRYPGGHEDVLRDFSFTAVPGELLVVTGPSGAGKSTL
                     AALLLRFYDPDAGSIRLDDIPVHRMPLAQLRHNITLLPQDTLVLHDTVAENIAAGRPHG
                     RATHHDVERAARAADAHDFISALPDGYDTVIAPGTARLSGGQLQRVAIARAMLRDAPVL
                     ILDEPTTGLDVLATQRILGPLRRLAEGRTTLVITHDLDLAADADRVLVLDRGLLVESGT
                     HAQLLAQRGLYATLFHAHPPSHPHNGTPNPAVGRGGIVG"
     gene            19654..20199
                     /locus_tag="STRMOE7_RS38495"
                     /old_locus_tag="STRMOE7_21175"
     CDS             19654..20199
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539347.1"
                     /locus_tag="STRMOE7_RS38495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_21175"
                     /product="hypothetical protein"
                     /protein_id="WP_180290082.1"
                     /transl_table=11
                     /translation="MDALAKPADGQPEPGTGVAVRDIVRSVVAELAPDELVLVEGLWRY
                     DDDSVVARLAGRRRSREPLGFGLQEVTALITPVAWLVLDEAARKVVGTAVTSATDRTRG
                     WLRRVTRRPAAVRTLPPLSEEQLAAVRARVLELGTESGLAPETATALAERVVARLVLRP
                     QGRLPNDAGSDGSAEPEA"
     misc_feature    20640..20655
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.11"
                     /tool="antismash"
     misc_feature    20641..20655
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.53"
                     /tool="antismash"
     misc_feature    20908..20922
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(21023..21034)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
ORIGIN
        1 tcggtgtagg cgagcgccac cttctccgga tcgcgggtgt tccacgcgtc ctcggcggcc
       61 tgcacctttt ggagcgcgct cggctcgtcg aacgggggga ggggcgggcg gggtgccatg
      121 gcggggtcct tgtctccgta cggaggagaa cgagcgttct ccgctgcttc ggctagtgta
      181 gagaacgatc gttctcgcgc aaggccgaaa ccgtcgggga gccatggatc aggaagaagc
      241 ccgtacgcgg atactcgacg ccgcggagcg gctgttctac gcgcgcgggg tacaggccgt
      301 cggcatggac gagctgcgca ccaccgccgg ggtctcgctc aagcgcctct accagtgctt
      361 tcccgccaag gacgacctcg tcgaggcgta tctgcggcgg cgcgacacac ggtggcgggc
      421 cgcgctcgcg gagtacgtcg aggggcgcgc cgcggggtcc ggggagcggc cgctcgcggt
      481 cttcgactgg ctgcacgact ggttcgctga gccggacttc cgcggctgcg ccttcctcaa
      541 ctccttcggg gagctggggg cgacctcgga cggggtcggc cgcgtcgccc gggagcacaa
      601 gcgggccctg ctggcgtatc tgaccgggct cgtgcgggcg ctgccggtgg acggaccgga
      661 cgcggtggcg ggtcagttgg cgctgctcgt cgacggggcg atcaccaccg cggcgctcac
      721 tggcgacccc gcggccgccc ggcacgcccg taccgccgcg gggagcctgc tggcggcggc
      781 gggcgcacgc gaggcgtgac gcgccgccgc cgccggatcc ggggccggtc gtccgccggc
      841 tccggggtta cttccggggt gttactggag gtggcccagg gtgcggaccg cctcgtagta
      901 cttcttggcg accttcaggc agcccttgcg ctgcaattcg gtgtacggac cccactgcct
      961 cttgcactgg ttctgcatgt cctcgaggaa ggagtcgtcc acccgcttct tgtgcgcacg
     1021 ggtgaattca tgcatcttct tgtaattgcg gtaaccgaaa tcgtgccggg cgcaggactc
     1081 ccagaagtgg aaaccgccgg ggttgtcgct gacgtgggaa cagccgtcgg tgccccagtc
     1141 gaagcggtac gcgtcgtgcc cgtcctgcca cttgatgcgg gtgttctccc acagcggcat
     1201 tgcgtacttc tcggtcagct ggttgagccg cttgagcttc tgcgccttgc tgatcgccgc
     1261 cgcctggtgg tcagccgtgg cggaggacgt gcgcaccgtg gagccgtccg ggtgcgcggg
     1321 gccggcgagc gccggggtgg ccgcggagag cgcgagtacg ccgctcagtg cggcgccggc
     1381 caaggacatg ccgactttct tcacgtgtaa ttcccccatt ctcggagctt ccgggcgcga
     1441 tcgtcccgga agcgttacgc ggccggccgg agaaaggtgg tcagggcacg gcaaggcacc
     1501 cacgtgaaag cgaaagtgcg tccgtgcgtt cttcccccga actgaccgcg cccgaagatt
     1561 aacacgccat caattcatcg acaggccaaa ggaggaaaag atccggacgc gggaattccg
     1621 ccgagaatgc ggaatgaatt gctcctcatg aggaaacgaa gaggcgagtg ggccttcccc
     1681 ggcccactcg cctgatgcaa cgtcagagcg ctcagcccag cacccgctcc aaggaggcca
     1741 gtgccgaggc cagttcctcc tcggtgatgg tcagcggcgg ggcgagccgg atcgtcgagc
     1801 cgtgggtgtc cttgaccagc acgccttcct tgaggaggcg ttcgctgatc tcccggccgg
     1861 tgccgagggc ggggtcgacg tccacgccgg cccacagacc gcgggcccgg aatccggtca
     1921 cgcccttgcc ggtcagcgcg gtcaggccgg cgcgcagctg ctcgccccgc tcggccgccc
     1981 ggcgctggaa ctccccggtg gccagcaggt cgatgacggc cgaaccgacc gccgccgcca
     2041 gcgggttgcc gccgaacgtg gagccgtgct ggccggggcc gagcacgccc aggacgtcgc
     2101 gccgggcgac gaccgcggag accgggacga tgccgccgcc cagcgccttg ccgaggagga
     2161 gcacgtcggg gacgacggac tcgtgctcga cggccagggt cgtgccggtg cggcccagcc
     2221 cggactggat ctcgtcggcg atgaacaggc agccggcgcg gcgggtcagt tcgcggacgc
     2281 cggtgaggta gccgtcgtcg gggatcagca cgcccgcctc gccctggatg ggctcgatca
     2341 gcaccgcggc ggtggtctcg tccacggccg cttcgagcgc ggcgaggtcg ttgtagggga
     2401 cggtgcggaa gccgggggcg aacgggccga agccgacacg ggcggtgtcg tcgtcggaga
     2461 agccgacgat ggtcgtcgta cggccgtgga agttgccgcc ggccaccacg atcgtcgcct
     2521 tgtccgcggg gacgcccttg acgtcgtacg cccacttgcg ggccaccttg atgccgctct
     2581 cgaccgcctc ggccccggtg ttcatcggca gcaccatgtc caggccggtc agcgcggcca
     2641 ggccctcggc gaaaccggcg agccggtcgt tgtggaaggc gcgcgaggtc agggtcagct
     2701 ggtcgagctg gcggtgtgcg gcctcgatca ggtccgggtg ccggtggccg aagttgaggg
     2761 ccgagtaacc ggccagcatg tcgaggtagc ggcgcccctc gacgtcctcg acccagacgc
     2821 cctcggcacg cgccacgacc accggcagcg ggtggtagtt gtgcgccagg accggggcct
     2881 cggcctggat cagctcggcg gacgagcggg gcgcgccgac gacggcggta cgggtgggtg
     2941 cagtcatgag cggatctcct gggtgcagca cttgatgccg ccgccggcct tgtggaactc
     3001 cgagaggtcg acggggacgg ggacatagcc gcgggcggtg agctggtcga tcaggccggt
     3061 ggcctgcggg gcgatgaaga cgtgccggcc gtcggagacc gagttgaggc cgaacgccat
     3121 ggcgtcctcg cgggtcgcga gcaccgcgtc ggggaacagc cgcgcgagca cctcccggca
     3181 cccgggcgag aacgcgtcgg ggaagtacgc cacgttctcc tcgtcgaggg cgaacagcgc
     3241 ggtgtcgagg tggtagaagt gcggatccac cagctggagg ccgatggtcg ggacgccgaa
     3301 gaactcctgc gcctcgtggt gcgcggcccg cgccgtacgg aagccggtgc cggccagcag
     3361 gaagcggccc gccgggacca ggtcgccctc gccctcgcac accgactccg gccggtagac
     3421 gtcgaacccg gcggccttga accacgtttc gtacgcggtg gactccgggc gccgctccgg
     3481 cgcgtggaac agcgagccga agacccggcc gcgcatcacc accgcgcagt tcgccgcgaa
     3541 gaccatgtcc ggcaggccgg ggaccggcgg cacggactcc accgcgtgcc cgtgggcgcg
     3601 gtaggtgtcg atcagcgtgg accactgccg ggccgcgcgt gccgtgtcga ccggcacctc
     3661 cgcccgcatc cacggattga tggcgtagcg cacctcgaag tgcctgggct cgcagaccag
     3721 ataacgccgt ggactcgcca cacgactcgt cggcacagga gtaccccctc cgcttccgtg
     3781 cgaggacacg ttcctctgag gacatgcggg gtgaccagct gtcaccggtg gtcacccgcg
     3841 gtgcctcaac ggtaggaagg acgcattccg gccacaagaa acaaacgctg ctcagtggcg
     3901 cacgaatgct gcggagaagt gcaggtcaac gctgctttcc tgcgccgttt ccggtggcgg
     3961 accgccgggc gcccgcctcc gggctctccg gcagcagatg ggacagcacc atgtaactga
     4021 tcgtcttgcg gatgaacggc tccgccctga tccgctccag cacctcttcg aagtgctcga
     4081 cgtcggtcgc ccgcacgtgc agcagcgcgt ccgcgccccc ggtgacggtc atcgcggcgg
     4141 cgatctccgg gtggttgcgc accacctcgg ccagccgccg gggcggtgcc gcgctgtcgc
     4201 agtacacctc gacgtacgcc tcggtcagcc agcccagcgc ggccggccgg acggtcgcgg
     4261 tgaagccggt gatgacgttg gtttcccgca gccggtccac ccgccgtttg accgcggtcg
     4321 acgacagtcc gacggacgcc ccgatctccg cgaagctcgc ccggccgttg tcgatcagtg
     4381 ccttgacgat cttccggtcg agctcgtcga agggcacggc cttgtgggtc aagggacctc
     4441 ccgttccatc caggtgccgc tggcgtcgcg gtcgcctcac ggtagcggta gccggcccgg
     4501 cggtggcgta tcccccaccc cgcccgccaa acccccagtt caggtatcta tgcaggtcac
     4561 agggggtggc gtaacgtctc cgcgacaccg ctcgcccagc gtcggtgtcc cgctggcgag
     4621 ggtgaggagg ccgggccgtg cggcatgcga cggtgaggga cgacggggcc ggcgacgggc
     4681 tcacccgggc ggaccgggcc cggcgggtgg cgcacgtgct gcgcgggcag gtgctgcgcg
     4741 gggccttcgc ggacggggtc ctgccggacg aacgggccct ggtcgccgag ttcggcacct
     4801 cgcgcaacac cgtgcgggag gcgctcgggc tgctccgcga cgaggggctg gtggcgcggc
     4861 ggcggggcgt gggcacggtc gtcgtcggcc gggcctatca gcacccgctc ggcgaactgt
     4921 ccgggctggc cgaggtgctg caacggcacg gcacggtcgt caacgaggtg cgggaggcgc
     4981 gcagcgtacg gccgccgctg acggtcgccc gccggctggg cctggcggag ggcaccccgg
     5041 ccgtctatct ggagcggctg cggcgggtgg acggactgcc gctgtccctg gactgcacgt
     5101 acctcatccg ggaggtcggg gagccgctgc tggcgcgcgg gcgggagacg ctggaacggc
     5161 aggacgtctt cgacctgatc gaacgggtgg cgggcgcgcc actgggccgg gcggaggtgt
     5221 ccgtccaggc cgtggtggcc gacccggcga cctgcgcggt gctcgcgatg cccgagggcg
     5281 gcgcggtcct cgccgtcgag cgcctcaccc ggctcgccga cggccgcccc gccgacctgg
     5341 agttcatcca tctgcgcggg gaccggctga ccctgcacgc caccctcgac cgggcaacgg
     5401 gcgcgacgag cgggcgcggc ggcgggcggt cgcggggtgg gcatcgatga ccgggctcgc
     5461 cgcggtgccg ggcaatgtcg gcggcggggc ggccgtcggg tacggcggtt ggcggaccct
     5521 gttcgggtgt gcggtgccgc cggcgctggc ggcgctggtc gttcgcgtcg ccttcgccgt
     5581 gcgtcgactc cggcgggaca acacggtggc cggcacgagg agtaccgcgc cgaggaagaa
     5641 gtagccgttg atcaccatgg tcttccagaa gtcccatgac cctgtgtcga cggcctcctt
     5701 ctccatcccg agcaagccgt gcggagtaag tcccgtcgcc gtggtgacgt tctcgacgag
     5761 accgggcacg ccccgcatcg tcagtaccgc gcagccgatc cacaggggcg cgcgtaccag
     5821 ccagtgcggc gcacgtcggc cccatggttt gaccgtggcc agcacgcaca ccacgccgac
     5881 gaccgacatg aggacgatga gggcgtcgta ggagacaaag agccagagcg gagtgccgtc
     5941 gtcgggaccc atcgtggcct cgtacatgac gcccatctga acgtgccaca cgaagctcac
     6001 caccaaccag gcgacggccg cgtatgccca gcggaggaga gttttcccgg gttcggattg
     6061 catgacctcg acgctacgag ccggggcacg gacgaggcgt cggctcgcag gaggagcccc
     6121 tccaccgcac gggggagggg cggggcgaag ccgcccgtgc aggaacgtac gcactctgac
     6181 cagcgcggtc ttcaccgccc gccagccggc ggcgctgtcc ggccccggcc ggccgatgac
     6241 ggtggcggcg gccggggccg gaccccgccc ccggccgtcc gcggcggtag gcgggccgtc
     6301 ccggccgccc cgcgagaccc cgccctacac cggctccacc cgctgcagct tcgcccggcg
     6361 gacgacctcc gggcccagct tcgcggcccg ggccaccagt gccgggccgt cccagtccgt
     6421 cggccagccg tgccacaggc ggagtttccc gccgacgacg accgcggcga tctggtcgcg
     6481 gttcgccagc cggacgagtt cccagcgcag gtcgtaggag ggcgtcagct ccgggacttc
     6541 gaggttcacg acgaggaagt cggcggcctt gccggccgcg atctcaccgg tcaccccgcc
     6601 caggccgagc gcgtcggcgc tgcccgacgt cgcgtgttcc agccacgtcc gcccggctcc
     6661 gcacaccgag tcgcccgccg ccatcccgta cgccagccgc tgggcggtct ccccggcgtc
     6721 gatcatccgg aagccgtcgc cgcgggtgcc gtcggtgccc atgccgaagc gcacgcccat
     6781 cgcggcgagc agggtcgcgt gcgccacgcc gttgcccttc caggcgctgg cgaccgggtt
     6841 gtagctgatg gcggcacccg agtcggccag cagccgggtc tcggaggggg tgagcagggt
     6901 ggcgtgcgcg cccagggtgt gcgggccgag ggcgccgatg tggtgcaggt actccagcgg
     6961 gcggcggccg gtgctcttca acgagcgttc cacggaggcc agatgttcgt tgacgtggac
     7021 ctggagcacc gcaccggcct cggcgcacag gtcggcggtc ttcctgatga cgtcggcgga
     7081 cgcgtcctcg gggacggcga tggccagcga ggggtggatc agcggatgtc cctcccagcg
     7141 ccccaggtgc tccgggccgc cgctgccgga cgagacgatc ttgcccagga cgcagcggat
     7201 cccggcctcc tcggtgccct tcgcgagcgc ccggacgtcg acgggggccc gggtgccggc
     7261 atcggcgacg gtggtgaagc cgccgcgcag cgcctccagc gcggccagtt tcgccgagac
     7321 gtaggcgctc tcctcgtcca gtgcgtgttc cagcggctcc cacaccgttt tgaagatctc
     7381 cgacggctgg ccgaaggact gcgccttgcc gaagctctgg gtcagatggt gatgggcgtc
     7441 gacgaagccg ggcatcagca gatggccgtc caggcggacc ggtcgcaggt cccggtgggc
     7501 ggcgatgagc tgttccgcgg ggccgacggc gcggaacttc ccgccgtcca ccagcacggc
     7561 ccggccgcgg gccggcccgt ccggcaggag cagcagctcg gggaccaaca ggtgccggct
     7621 gccgtggaag tccgtgggcc gcggcccctt gtggggggtg tcggccgcgg cggtgccggg
     7681 ggcaccgatg cccgaggcgc cgacgaatcc gcccacgccg gccagaaacc cgcgccgtcc
     7741 gaagccgctg tgctgttcgt tcgccaaccc gctcgcctgc ttcccgtact gcggtacgtg
     7801 tgtacctctt gctggaccgt ccccggggtg gcctgaccct aggaccggcc cgtaagtgga
     7861 acaagggttc cggcatacgg gatttgcaag gtgcgggcgc gggtggcgga acgtcgccgc
     7921 gccctcggtg cgtgcctggt cagggcgggt ggccgggcgc cgccgggtgg cgtaacaccg
     7981 cggaaacatg gggccgctga cggtggggga gccgggcgcg tgggtccgcc ccgccccgcc
     8041 cggccccccg tgggatcctg gtgcgtcatg gatctgccgg gcggacggtg gacggacgtg
     8101 cggcgatgac gagggtgccc cgatgagact ctgcttcctg gtggaggagc agtaccgcta
     8161 cgacggcatg ccgctggacg tgatccgcca actcaccgcc tgggggcacc aggtggacgt
     8221 gctgtggccg ggccgctcgc tgctgccgct gtccgaggcg gtgcgggccg gcagccatga
     8281 cgcctgggtc ctcaagaccg tctccggcgg ccccggcctg accctcctgg aagcggcggc
     8341 cgcggtcggg ctgacgacgg tgaacgacgt acgggcgatc cggggggtgc gcgacaaggc
     8401 gctggccgcg gtgatcgccc gcggcagcgg actgccggtc ccggtgacct acgcggccgc
     8461 ccgggccgag gagttcgcgc agatacccga ggcggagttc cccctcgtcg tcaagcccgc
     8521 ggacggcagc tccgggcgcg cggtccggct ggtcgagacg ccggaccggc tgcccgccgc
     8581 cggcacggcg gagcccgcgg agccgggcgg ggcggccggc ggcctgctga tcgcccagcc
     8641 gtacgtgccc aactccggta cggacctgaa ggtgtactgc gtcgccggtg agctgtacgc
     8701 gaccgagcgc cgctccccgc tgcaccccgg gcaccccgta cgggaacgcc aggtcccgct
     8761 caccgccgag gtcgcccgga tcaccgcgga gatcggcgcg gtcttcggcc tcgacctgta
     8821 cggcgtcgac gtgctgctcg ggccggacgg cccggtggtc gtcgacatca acgacttccc
     8881 cagcttccgt caggtgccgg acgccgtcgc ccgggtctcc tccgccgttc tgcgcctcgc
     8941 ccgcaaggga gcggaaccgg cggttcccgg cccggccgcc cccgccgagc ccccgctggc
     9001 ggcgatcggc ggcgaccggt gaggatcggc ctgatcaccg cggacgccgc ccacccggtg
     9061 ctggccgcga ccggcgccct gctcgtcggg cagggccacc gggtcgaggt cgtggacccc
     9121 ggcggcgtgc ccgagggccc cggcccgctc gccgacgtct acctcctcaa ggcccgtacg
     9181 ccccgggcgc tggccctcgc cgcccgcctg gaggagcggg gcgccgcggt catcaactcg
     9241 gctgcggcga ccgcccgttg ccaggaccgg gtggcgatgg ccgagctggc ccgcggggcc
     9301 ggactgccgt tcgcccgcac ccgcttcgtg ggcacgccgg ccgagctggc cgcggccggg
     9361 gagccggccg gcccgctggt cgtcaagagc cgccacagcc ggcgcggcga cctggtggcc
     9421 cgcgccgaca gcgccgtacg gctgcgggag ctggccgccg agtggcccga ggaaccggtg
     9481 gtcgtgcagg acttcctcgc gggcagcggc tgggaccaca aggtgtgggt ggtcgacggg
     9541 cgactgttcg ccgggctgcg ccgctccgaa ctggccccgg agggccgcgg ggagacgctg
     9601 ccgctgccgc ccggcgaact gcccgcggac tggcgcgccc tcgcgctcgg ggtcggcgag
     9661 gtcttcggcc tggaggtcta cggcgtggac ctcctcgacg ccggcggcgg cgccccgctc
     9721 ctcgtggacg tcaacgcctt ccccggcatc cgcggccagg ccggcgcccc ggaggcactg
     9781 gcggaactcg ccctgcgtac gggggcacga gccggaagaa gggcgtcgga aaacggcccc
     9841 gaatgatcaa tgagcaacat cggtcgagcg gaaagggccg ggaggcggaa gctcctcctc
     9901 cgtaaggtct agtgcggcaa tccccggggt agcgctgccc ccgtcagggg ggcgtggtcc
     9961 agcacgtctt cctccacacg catggggaga ggccagaacg gtgaccaagc cattcgaact
    10021 gcccgacttc tacacgccgt acccggcgcg gctcaacccg cacctggagg cggcgcgtac
    10081 gcactccagg aagtgggccc gcggcatggg gatgctggag ggctcgggca tctgggagca
    10141 gcgggacctc gacgcccacg actacgccct gctctgcgcc tacacccacc ccgactgcga
    10201 cgcggcggcg ctgtcgctcg tcaccgactg gtacgtctgg gtcttcttct tcgacgacca
    10261 cttcctggag aagttcaagc ggacgctgga ccgcgcgggc ggcaaggagt acctcgaccg
    10321 gctgcccgcc ttcatgccgc tggacctcgg cgcgccggtg cccgagccga ccaacccggt
    10381 cgaggcggga ctcgccgacc tgtgggcccg caccgtgccg cacatgtcgg cggactggcg
    10441 ccggcggttc gccgagagca ccgagcacct gctcaacgaa tcgctgtggg aactgtccaa
    10501 catcaacatc aaccgggtgc ccaaccccgt cgagtacatc gagatgcgcc gcaaggtcgg
    10561 cggcgcgccc tggtcggccg ggctggtgga gtacgcgacc ggggccgagg tcccggcccg
    10621 ggtggccggc tcccgccccc tgcgggtgct gcgcgacacc ttctccgacg ccgtccacct
    10681 gcgcaacgac ctcttctcct accagcggga gaccgaggag gaaggcgagc tgagcaacgg
    10741 agtgctggtc ctggagacct tcctggactg caccacccag gaggccgcgg acgccgtcaa
    10801 cgacctgatc acctcacggc tccagcagtt cgagaacacc gtggtcgccg aactcccgcc
    10861 gctcttcctg gagaagggcc tcgacccgaa gtcctgcgcg gacgtcctcg cgtacgccaa
    10921 ggggctgcag gactggcagt ccggcggcca cgaatggcac atgcgctcca gccgctacat
    10981 gaacgacggc ggggcggcgg ccggcgccgc acccccctgg tcgccgttct ccgccggcgg
    11041 cctcggcacc tcggccacgg acctcaagaa ggccctggcc acggccggcg cgcaccgcgt
    11101 ccgcagccac acccacgtcc cgcaccagca ggtcgggccc tcgcggatcc ccgacttctg
    11161 catgccgttc ccgctcaccc tgagcccgca cctggagggc gcccgccgcc gggtcatcga
    11221 ctgggccgac cggatgggtc tgctccagcc gcagcccggc gtgccgctct ccgacgtctg
    11281 ggacgaggcc gcgatggccc gccacgacct ggcactgtgc gcggccggca tccacccgga
    11341 cgccactccc gagcagctcg acctcgactc cgcctggctg gcgtggggca cctacgcgga
    11401 cgactactac ccgcaggtct tcggccggac ccgggacgcc gccgcggcct atgcgtgcac
    11461 cgaacggctg aagctcttca tgccgctcga ccccgcgacg accccgcccg agccggtcaa
    11521 cgccatggaa cgcgcactgg ccgacctctg gccccgtacg acccgcccga tgacgcccga
    11581 ggcccgccgg gccttccgcg cggccgtcga cacgatgacc gccagctggc tctgggagat
    11641 cgacaaccag atccagaacc gcatcccgga tccggtcgac tacatcgaga tgcgccgggc
    11701 caccttcggc tccgacctca ccatggccct cagccgcctc ggccacggcc ggcacgtccc
    11761 gccggaggtc taccgcaccg gcaccctccg ttcgctggag aacgccgccg ccgactacgc
    11821 cgccctgatg aacgacgtct tctcgtacca gaaggagatc gagtacgagg gcgaggtgca
    11881 caacggcatc ctggtcgtcc agaccttctt cgactgcgac tacccgaccg cgctggccat
    11941 cgtcaacgac ctcatgacct cccgcatgcg cgagttccag cacgtcgccg cgaaggaact
    12001 cccggtcgtg tacgacgact tccagctgcc ggccgaggcc cgcgccacgc tcgacggcta
    12061 tgtgcgggag ctggagaact ggatggcggg gatcctcaac tggcaccagg gctgccggcg
    12121 ctacatcgag ccggagctgc gccacccggt gggctcaccg ggccggctcg gtgccccgtc
    12181 ggggctgggg acgtcggcgg cccggttctt ccagcgagcg gccgcgggcg ccggatgacg
    12241 cgggcgggcc ggtgaggggc gcgtccgccg ggccggtagc gcaccgccgc ggccgggcgc
    12301 gcgtgccccc tgtgctcctg cgccgggcag gagcacaggg gggcggcggc ccgggcgcgg
    12361 aaaccgctcg tgagcgtgcc gaactggctc gttgtcagct ccttgccgcg atgaccgggg
    12421 cgcgggaggt gctgtggctg gggagcgggt cgcgtggcga tgggtgaata tccgtttcga
    12481 ggtgaatagc ccgatattcc gtcgggaacc ttggcgtcat gcgacacaag accgccttcc
    12541 tcggagccgt ggccgccacc ggtgcctttg ccctgctcgg cccgatcgcc gcccaggcca
    12601 ccaccggcac catcaccttc cacatgcgct cgcggaacaa ggactaccag atcgtcgacc
    12661 ccggtgacga tcactgctac ggcctgggcg acgggggcgg cctggtggac aacgacaccc
    12721 cctcgacctg gtgctgtggt cctcccgcga ctgcacgggg cgcgccatgg cgaccgtacg
    12781 ggccggcagc tccgcgcggt tcgcgcggta cggcagcctg cagctggacc cggccagcgc
    12841 ccccgcgccg tcgtacccca gcgaatcccg ggacccgggg gactcccgtg accccggcga
    12901 ctaccaggac ccgtccgact cccgcgaccc gggcgactcc cgtgacccgg gggactaccg
    12961 ggatccgtcc gacaggcgcg attccgggga ctcccgcgac cccggtgact acaacgatcc
    13021 gtccgactcc cgtgacccgg gacgcgaccg ggacaccggc gactcccgtg acccccggga
    13081 ctccgacgac tacctggacc cgggcgacgc gcgggacacc ggcgacgcgc cggaccgccg
    13141 cgaccctcag gacccggccc gctcctcgga ccccggtgac cccagcaccc tccccgcccc
    13201 ggccggtgcc tcggacccgg tcaactcccc gggtgccgcc gtcccccggc gcgtcgcccg
    13261 gccgtcgtcc agctcaccca ccaagtcgag cgcccgcccc gggcgcgtcg cccggccgtc
    13321 gtccagctca cccaccaagt cgagcgcccg ccccaaggtg atcaagcgct cctgaagcgt
    13381 gccgcccgcc gggtagagcc gtacggtgcc gaccccggcg gcgcgccaca cccgcaggcg
    13441 ggccggtccg cctcatggcg ccaggacacg ggcggccccg ccggaccggc gatcacaacc
    13501 gaccccgcga ccacggccag gagggcggag gacggcatgc ccgaactgcc cgacgtcgag
    13561 gcgttccgcc gcaccttcgt ccgttgcgcg caacgacggg tggtccagca catcgagatc
    13621 cacgacgcgg gcgtgctgca cgggctgagc ggccgtcagc tgcggcacga actggagggc
    13681 cgcaggttcg ccgagcccga gcggcacggg aagtggctga tcgcccgcac cgggggcccc
    13741 atcctgctgc tgcacttcgg catgaccggc cggctggtgt gcaccgcacc ggaggaggcc
    13801 gcccaccccc acgaccgggt ggtcttcacc atgagcaggg agcaccggct ccgctaccgc
    13861 gaccagcgca aactccaggg cctgtggctc gtcgacgagg ccggactgga ccgggtgctg
    13921 ggccgtctgg gaccggacgc ggcaacggtg ccgcgcgacg ccttccgggc ggcgctcgcc
    13981 gcccgccggg gccgcctcaa ggcgctcctg atggaccagt cggtgctggc cggactcggc
    14041 aacctcctcg tcgacgagat cctctggcgc acccggctgc ccccgtcccg gccggcccgc
    14101 gacctcaccg acgaggaggg cgaccgcctc cacacggagc tgcgccgcac cctgcgcgcg
    14161 gcggtgcgcg cgggctgcgt gccaccccgc gacacctggc tgaccggccg ccgcgacgac
    14221 cccgacccgc actgcccgcg ctgcggcggc ccgctgcgcc gcggccgcgt cgcgggccgc
    14281 ggcacggtgt ggtgcccccg ctgccagccc tgacccggcg gaccccgccg ggcccgaggc
    14341 gctcaccgga gccgcgggcc ccggccggcc gagccgcctc ctcagcgccg ggcggccctc
    14401 ggtgacgggc gcggggcagc cgccggtgcg agcgggccgg ctcccttgac ggtgcgcagg
    14461 accggggcgg tctccagggt gtggatcgcg cgcaggccgc ccagccgccg ggtgagatag
    14521 cggtgcaggg ccgccgggtc ggggcacagc gcgtgcgcga ccacgttcgt gcggccggtg
    14581 gtggcggcga cgaaggcgag ttcgtggtgc ccggccagcg cggtggcgac ccggtcgagg
    14641 tgggtggggg agacggtcat ccacagcatg gcctgggtgg tggcgccgaa cagcgcgtcg
    14701 tcggcctcga cgtcgaagaa gagcgcaccg gcggcccgca gcgcggccag ccggcgggcc
    14761 acggtcgccg gtgaccaccc ggtggcggcg gccagatcgg cctggccggt acggccgtcc
    14821 cgctccagcg ccgcgagcag cgcgtggtcg gcctcggtca acacccgccc ggcctcggcg
    14881 agttggccgt cgtgcggccc ggcgccgggt ggtgcgagcc ggcgctgctg gtcctcgtcg
    14941 agggtgccgg cgcggccccg ccaggcggtg gggccgccga ggtaggtgtg gagcaggcag
    15001 tgggcggaga ccgcggtgat gccggcggtg cgcgggatgt cgtgcagcag cagcgcgtgg
    15061 ccgccggtgc cgtcggccgg ggtgtgcacg accgcgagga tctcggtgcc gccggaggcc
    15121 agtttcaccc aggaggtgtc cgtccgccgg gccagggcgc gggccaggtc ctgcgcgctg
    15181 tgcggggcgg cggtcagccg caccagccac tgcgcccggc cggcgcggtg cggatcggcg
    15241 agcccgacga cccgcagtcc ggcgtcggcg cgcagcctgc ggtagcggcg cgcgacggtc
    15301 tgcgtcgaga cgcccagcac ctcggcgatc cggctgaacg gggcccgccc gtcgaggtgc
    15361 agcgcatgga cgatcccgcg gtcgacgtcg tcgagcaccg gcaccccggt cgtggccgcg
    15421 tccctcatgg tgatcccctc cgtggtccgc ccgtggggcg cgggtcccgg ccgcccccgt
    15481 ggtgcggaga aatccttgcg tccggacaag tccgtgcgtc cggacaaatc cttcagcaca
    15541 cgcgcccgga tggaaaacat cagcgatctc cggctcgtgg agggaacacc cggtggacgc
    15601 cggcgcacgc tctgcccgta ctccaccgaa gggaagagcc atgccccagc ccctgcccca
    15661 ccccctgccg cccgtacggc cgatgccgta cccccgccgc tggtgcgccc tcgcggtgct
    15721 gctggtcgcc gaggcgatga atctgctcga ctccacgatc atgacggtcg ccgcaccggt
    15781 gatccacgcc gatctcggcg ggcccgcctc cggcatccag tggttcagcg ccgcctacac
    15841 cctgccgttc gcggtgctgc tgatcaccgg gggccggctc ggcgacatcg ccgggcgcaa
    15901 gcgggtcttc cgggccgggg tggcggcgtt cgtgctcgcc tcggcgctct gcgcgctggc
    15961 cgcgtcaccc acgatgctga tcaccgcgcg ggcggtccag ggcgccgcgg ccgcgctcgt
    16021 catcccgcag accatcgggc tgatccgcgg catgttccac ggcgacgaac tggcccgggc
    16081 gatgggcagc atcggcccgg tcatgggcct ggccgcggtg tgcggcccgg tgctcgccgg
    16141 agtgctcacc cacgccgacc tgttcggctc ctcctggcgg gcggtgttcc tggtcaacgt
    16201 gccgctcggc ctcggtgtcc tcgccgcggc gccgctgctg cgcgaggacc gctccgagcg
    16261 gcggccgcgg ctggacctca ccggtacggt gctggccgtc ctggccaccg gcgcgctcgt
    16321 ccatccgctc atcgggtccg ggccggaccg gggatcaccc ggccgctggg tccttttcgc
    16381 cgcgggcctg tgcctgatgg cgctgttcgg ggcgcaccag cggcgccgga cggcccgggg
    16441 acgcagcgcg cttgtcgaga cccgcctctt cagcgaccgg ggattccccg ccgcgctggc
    16501 cgccgccgtg ctgttcttcg cggtggtcaa cggcctgatg ctggtcgtcg tcctccagct
    16561 gcaactcgga ccgcacaccg acgtccgctc cgcggggctc accctgctgc cgtggtcggc
    16621 ggcgatggtg gtggcgtcct ggaccgcggg cgcccgcctg gtgccccgcc atggttcccg
    16681 ggtgatgttc gccgggctcg ccgcactgct cctcggcacc ctgggcgccc tcgtcgtcta
    16741 cgccaccggc cggcccgcgg cgtacccgtg gccgttgctc gccgcgctga ccgccgccgg
    16801 actggggcag gggctgttct ccgtgccgtt cttcaccacc gcgctgggcc gggtccgccc
    16861 gcacgagacc ggttcggcgg cgggcctgct caacgccgcg cagcagctgg gcggcacgct
    16921 cggcgtcgcc ctgctcggca cggtcttcct gcacaccgcc cccggcgccg gtgccccggg
    16981 cgcgcgggcc gcgctcctcg gggcccgcga cgcctgcggg gcggccgtcg ccctcctcgc
    17041 cggcaccgtc gccgccgccg tcctgctgca cgccgctgcc cgcacccggc ccgcttcccc
    17101 gcggcgggac cgccgcgtac ggaacgccaa gtccccgtcc ggctacggga ggtgaccctt
    17161 gcctggtggg gggcgccggt gctgtcgcgg ccatgccgcc tccggagggt cacggatcgc
    17221 cactttgtgg tggtacacga agaattttgc tgtttgtctg aattttcacg cacatttcct
    17281 tgttggtagg caggtcatgg acgtagcttg ggagttgacg cagtcggaaa cggctcgtca
    17341 gcaaggaaaa gaacttctag gaggcgagaa tgagcttccg taaggtcttc ccacgcaggc
    17401 gcagagacga tggttggggt tacgaccacg accacggccg ccgccgtcgc aggtatcgcc
    17461 gccgcttcgg ccgcaggcgt cgtcgtttct tcggctacga caactactga ccaaaagctc
    17521 tgagctcgag gctgactcgc gtgccacgcg agtccgcctc gtgtgcttgg ggcccgtgca
    17581 cgtttccgag cagcccgata tggcgtggcg cccatgcatc tgcatagttc tcgcgggcac
    17641 ccggcacccc tggaggagcc gccgcccccg ccccaacccg gcacggaatc cccgcctgtt
    17701 gaccacggca tgtggagcct gcagacggac ctcacgatcc gcaccaggcg cgtcggcctc
    17761 aaggaatcac tccgccgctt ctggccactg acccacggcg accggcgctg gatcgtcctg
    17821 atctgcctgg cggccgtcgc cgccgccctc gccgagaccg tggccatcct gctcttcgcc
    17881 caactcaccg acaaggcact gcagaagggc tcggtcagcg ccttctgggt gcccgcggcc
    17941 atgtggctcg gcgtcgccgt ggtcggcgcg gtggtgggct atctcggcaa ctcgctcggg
    18001 gcctggaccg ccgagcgctt cgtcatgcgg ctgcgtgccc gggtcttcgc ccatctgcag
    18061 acgctccccc cgcacttctt ccagcgcagc cgccgcggtg acctcgtcga gcggctgacg
    18121 ggagacgtcg acgccatcga gcagatggtc atcaccggcc tcgtccaggt ggccgcggcc
    18181 ctgttcggca tcatcttcta cgccggtgcc gccctctggc tgcgctggga cctggcactg
    18241 gccaccttcg tcctggcccc gctgttctgg accgccaccc gccgcttcac cggccgggtc
    18301 aaagaggtct cccgccgcga gcgtgccgcc gacggcgcca tcacctccgt cgtcgaggag
    18361 ggcctggtca acgtcgtgct gacccaggcg tacaaccggc agcgcgacga ggaggagcgg
    18421 ctcgaccgcc aggcgcgcaa gtggttccgg gcgtcggtga ccagcgcccg cctcaacggg
    18481 ctctacgacc aggtcgtcga gctcctggag accttctgcg tgctggcgat catcggcctg
    18541 ggcgcctggg agatctccgc cggccggatg accctcggcc agctgctcgc cttcgccgcc
    18601 ttcgtcggct acctctaccc gcccatccgc tccctgggcc agctcggcct gaccgccacc
    18661 gaagcgaccg ccggtgccga gcgcctcctg gagatcctcg acgcccgccc cgccgtcagc
    18721 gacccggcgc cctccctggt cgccccgccg cgctaccgcc gcgccctcgg cgaggtggag
    18781 gcccggcacg tccacttccg ctaccccggt ggccacgagg acgtcctccg cgacttctcc
    18841 ttcaccgccg tccccggtga actgctcgtc gtcaccggcc ccagcggcgc cggcaaatcg
    18901 accctggccg ctctgctgct gcggttctac gaccccgacg cgggcagcat ccgcctcgac
    18961 gacatccccg tgcaccgcat gccgctcgcc cagctgcggc acaacatcac gctgctgccc
    19021 caggacaccc tcgtcctgca cgacaccgtc gcggagaaca tcgccgccgg ccgcccgcac
    19081 ggccgcgcca cccaccacga cgtggaacgc gccgcccggg ccgccgacgc ccacgacttc
    19141 atctccgccc tccccgacgg ctacgacacc gtcatcgccc ccggcaccgc ccgcctctcc
    19201 ggcggccagc tccagcgcgt cgcgatcgcc cgcgccatgc tccgcgacgc ccccgtcctc
    19261 atcctcgacg agcccaccac cggcctggac gtgctcgcca cccagcgcat cctcggcccc
    19321 ctgcgccgcc tcgccgaggg ccgcaccacc ctcgtgatca cccacgacct ggacctcgcc
    19381 gcggacgccg accgcgtcct ggtcctcgac cgcggcctgc tcgtcgagtc cggcacccac
    19441 gcccaactgc tcgcccaacg cggcctgtac gccaccctgt tccacgccca ccccccgtcc
    19501 cacccgcaca acggaacgcc caaccccgcc gtgggacggg gcgggatcgt cggctgagcg
    19561 ctccgggggg acaaagtcct gtggaaaacc gcccgcgcgc gtggcggcgc acttacgatg
    19621 cgtgggcgag agtgcgttcg gtgagggggg cggatggacg cgttggcgaa gccggccgac
    19681 gggcaaccgg agccggggac gggcgtggcg gtgcgggaca tcgtccggtc ggtcgtggcc
    19741 gagctggccc cggacgagct ggtgctggtc gaagggctct ggcggtacga cgacgacagc
    19801 gtggtggcgc ggctggccgg ccgccgccgc tcacgtgaac cgctcggctt cggcctccag
    19861 gaggtcaccg cgctgatcac gccggtggcc tggctggtgc tggacgaggc cgcccgcaag
    19921 gtcgtcggca ccgccgtcac cagcgcgacc gaccgcacgc gagggtggct gcgccgcgtc
    19981 acccgcagac cggcggcggt caggacgctc cccccgctga gcgaggaaca actggccgcg
    20041 gtgcgcgcgc gggtcctgga gctggggacg gagagcggcc tcgcgccgga gaccgccacc
    20101 gcgctcgccg agcgggtggt ggcgcgcctc gtgctgcgcc cgcagggccg gctgccgaac
    20161 gacgccggaa gcgacgggtc cgccgaaccc gaggcgtagg gagcgacacg tgagccggac
    20221 catggccgca ccgccccgcc cgaccgtcga cgagcgcgtt ctcggcgccg gcaccggact
    20281 gcgcttcgca ctgctgctgg tgctgttcct gaccagcagc gccacgatcg tcaaccagat
    20341 cgtcgaggtg ctggccgatc cgcgcaacat ccgcgtcggc tgcgcgctcg cggccggtgc
    20401 cgacccggag agcgactatc tgggcatcgg cctggccgcg gtgcgcgccg gtgacgccta
    20461 cccggcctgc gtgcgccggt acgtgcccac cgccgccgcg tgggtgccgt tcgccgtcct
    20521 cgctgccctg ctgatcgcgg ccgccgccgt gtactggctg ctgccccgct ggaagggccg
    20581 ccgcggccgc gtcgtaccgc tccgagccgt cgaccccgaa ggggagttac gcccgctcct
    20641 ggacgagctg gtccgggtcg ccgggctgtc ccgcccgccg cggttcgtcg tggcaccggc
    20701 cgcggccacc gccggcgcgg tggtcttcgg acggctgcgc cgctactccg tctgcctgca
    20761 cggtggcctg gtcgcccgcc ggcgccggga ccccgagggc ttccgcgcgg tggtcctcca
    20821 cgaactcgcg cacctccgca accacgacat cgacgtcacc tacgccacgg tcgccctctg
    20881 gcgggtcttc ctggtcgccg tcctgccggc ctacctgttc cagatcgcgc aggacctcaa
    20941 ggactccgcg gcgtccgcga tcctcggccc cgcggaacgc ctcggcaacg ggcacgaact
    21001 cctcctgtcg ggcgtgatga tcgcgttcgt ctacctcgcc cgcgcggaca tcctgcgcac
    21061 ccgcgagaca tacgccgatc tcgacgccct cgcctgggga gccgacgccc ggggctggca
    21121 ccacgccgcc gcacacggca ccggcaaggc cgccgcaccc ggccggctcc gcagggcgct
    21181 ggcctcgttc accgcgctgt ggcgcaccca cccggcatgg gaccggcggc tggccgcgct
    21241 caccgacccc cgggaactct tcgcaccgca cgccctgacg ctgttcgtgg ccggcgccac
    21301 cgcgacgatc gccggcgacc agctgatcga cgtgctgaac ggccccgggg ccggcggagc
    21361 actccgggtg ctgacggcac tgcaagcggg gctgatcgtg gcgattcccg gcgtctccgt
    21421 gtggcgggcg gtggcgcggg cggtcctcac cggcggccgg atccccaccg ggctgcgagc
    21481 gggctggtgg acggggctcg gcctcgcggt cggcgagctg ctgacgagca gcacctccgg
    21541 cagcacacga tggctgccca gccaccccga ggcgctcacg gtgctgatcc tcatcagcgt
    21601 gggactcatg tgctggacgg cgcagttcgc cgagctgtcg gtgcgctcct ggcgcggccg
    21661 tacgctccgg cccgccatgc tcctggggct ggccgcgatc tgggtggtct tcgccctctg
    21721 gtacgcctgg tggcaggccg acgggcacac cttcgcgacg ggctgggcgt actccgaaac
    21781 cggcatccgg gacgcgctgc tgcacgatct gccgggcacc gtccccgcgg accgcgacgt
    21841 gctcgccggg ttcgccgcgg cgctgccgct gctcctgccg atcggcgtga gccccttcat
    21901 cggctgggcc gcggccgtgc tgtggctgct gccgctgctc gcctggacgc gccggccggc
    21961 gaccggcgta ccggagtggg cccgccgggc cctgcgcggc gcccccgccc cggagctctc
    22021 cggaccgctg ctgccgccgc tgcgccgggt cctgctcgcc accgccgcgg gcaccgcgct
    22081 gtgctgggtg ggcacggtcg ccctcatggc cgtcatgcac acctggcagc cgcccccgga
    22141 gcggcgctac ggcacgtaca tgctgatcca cctgacgttc gtgctgctcg tcgtggtctg
    22201 cggcacgctc accgcggccg ccctgaccgg cctgacgg
//
