LOCUS       NZ_CP019779            22682 bp    DNA     linear   CON 14-MAR-2024
DEFINITION  Streptomyces sp. MOE7 chromosome, complete genome.
ACCESSION   NZ_CP019779
VERSION     NZ_CP019779.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MOE7
  ORGANISM  Streptomyces sp. MOE7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8399509)
  AUTHORS   Elnahas,M.O., De Leon,K.B., Amin,M.A., Hussein,M.M.D., Ali,A.E. and
            Wall,J.D.
  TITLE     Complete Genome Sequencing of Streptomyces sp. Strain MOE7, Which
            Produces an Extracellular Polysaccharide with Antioxidant and
            Antitumor Activities
  JOURNAL   Genome Announc 5 (22), e00442-17 (2017)
   PUBMED   28572320
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8399509)
  AUTHORS   Elnahas,M.O., De Leon,K.B., Amin,M.A., Hussein,M.M.D., Ali,A.E. and
            Wall,J.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2017) Biochemistry, University of Missouri
            Columbia, 117 Schweitzer Hall, Columbia, MO 65211, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 8.1
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002090335.1-RS_2024_03_14
            Annotation Date                   :: 03/14/2024 02:19:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,435
            CDSs (total)                      :: 7,344
            Genes (coding)                    :: 7,005
            CDSs (with protein)               :: 7,005
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 339
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 339
            Pseudo Genes (frameshifted)       :: 230 of 339
            Pseudo Genes (incomplete)         :: 155 of 339
            Pseudo Genes (internal stop)      :: 7 of 339
            Pseudo Genes (multiple problems)  :: 47 of 339
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:50:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4315524
            Orig. end                         :: 4338206
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019779.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Judy D. Wall 117 Schweitzer
            Hall Columbia, MO USA 65202.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22682
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="12"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22682
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22682
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12682](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12682)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            53..1393
                     /locus_tag="STRMOE7_RS19125"
                     /old_locus_tag="STRMOE7_19095"
     CDS             53..1393
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056545.1"
                     /locus_tag="STRMOE7_RS19125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19095"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_084771985.1"
                     /sec_met_domain="PALP (E-value: 7e-45, bitscore: 152.4,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYDSITDAIGDTPLVRIDPAVHGLRHIDLYAKLEMLNPFGSVKD
                     RAAWNMARPGLPDAVRRGATIVELSSGNTAKALAVIAGMHGLSFKSVTNRMRVPEIKEL
                     LLLLGAEIEELPGRSECLDPTDTEDPLTLFHQELARPGQPSLHTDQYFNDLNTAAHAAG
                     TGPEIIADLDGRAPDWFLACVGTAGSSTGVARALRAHDPAVRVVGLVGEKSDFIPGIRT
                     LDEVHEVGLFDPATYDTIEAVGADDALDGMLTLIRRCGLLAGPTGGAAYHGAVRHLRPL
                     DDGLAAEAGADGRRRTAVFIVCDRVESYLSYIRERRPELLGRPPARNSVATLTDAEIRA
                     TTVIDTTDARKWIAAERPLVVDLRGPFAYAALHIDGSVNIVDELFDELLRGGLPFSKRQ
                     PVLLACPVGEKSVRYAALLTRMGHPDVRSLAGGIIAWRDAGAPLVRD"
     gene            1395..2630
                     /locus_tag="STRMOE7_RS19130"
                     /old_locus_tag="STRMOE7_19100"
     CDS             1395..2630
                     /NRPS_PKS="Domain: Aminotran_5 (42-403). E-value: 5.7e-79.
                     Score: 257.6. Matches aSDomain:
                     nrpspksdomains_STRMOE7_RS19130_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005989.1"
                     /locus_tag="STRMOE7_RS19130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19100"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_084771986.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.5e-54, bitscore:
                     184.1, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 0.00023,
                     bitscore: 19.3, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRPVEDPPRRQAPDDDLAELRAWQRPLRAQFPIITAHPGLAYLD
                     SAATAQKPQAVLDAVLSYLTTSNANAGRGTYPWANATTALVEAARDRVKSFLHDPRPER
                     STVHFTSGTTEGLRTVARDWLATFLTDGDEIVVPFADHEANLAPWLEARDLLARRGIRV
                     RVRALPCQEGSGDYDPAALAAQLTPRTRFVAVTHVHHVYGADMNVHRIREVAGPAVPIC
                     LDAAQSIGHLPVSTAELDVDFVVFSGHKALAPPGTGVVWARGLRGPRFRPGGWQGTPNT
                     AGIAGLAAALDWLDAAGTDRIERWTVALAARLTDGLGRLDAYEILGCRESLSAASRVQR
                     RRSIVTFRHRGISSTDLGFILYSHGFMVRSDHHCQAGAQDGAQDGSVRVSLHVHNTPEE
                     IDALVSTLTSLQ"
     aSDomain        1521..2603
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STRMOE7_RS19130_Aminotran_5.1"
                     /evalue="5.70E-79"
                     /label="STRMOE7_RS19130_Aminotran_5.1"
                     /locus_tag="STRMOE7_RS19130"
                     /protein_end="403"
                     /protein_start="42"
                     /score="257.6"
                     /tool="antismash"
                     /translation="YLDSAATAQKPQAVLDAVLSYLTTSNANAGRGTYPWANATTALVE
                     AARDRVKSFLHDPRPERSTVHFTSGTTEGLRTVARDWLATFLTDGDEIVVPFADHEANL
                     APWLEARDLLARRGIRVRVRALPCQEGSGDYDPAALAAQLTPRTRFVAVTHVHHVYGAD
                     MNVHRIREVAGPAVPICLDAAQSIGHLPVSTAELDVDFVVFSGHKALAPPGTGVVWARG
                     LRGPRFRPGGWQGTPNTAGIAGLAAALDWLDAAGTDRIERWTVALAARLTDGLGRLDAY
                     EILGCRESLSAASRVQRRRSIVTFRHRGISSTDLGFILYSHGFMVRSDHHCQAGAQDGA
                     QDGSVRVSLHVHNTPEEIDAL"
     gene            2668..3462
                     /locus_tag="STRMOE7_RS19135"
                     /old_locus_tag="STRMOE7_19105"
     CDS             2668..3462
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005988.1"
                     /locus_tag="STRMOE7_RS19135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19105"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_084776244.1"
                     /transl_table=11
                     /translation="MSGSSGTAEVRSDRSVSGATAARWVRRWEAQQQRYAVDREERLTV
                     ITDVVEDATAGRAAPLVVDLGCGPGALAARLAARLPHGEIVAVDADPLLLGLGRAYYGP
                     AVRFVEALIGRPGWLGALALDRPLDAAVSTTALHYLGEAALRRVYRDLADRLRPGGVLV
                     NGDHLRQEAGRLCEIARAVGRRRAERQRACGHEDWDSWWAAAHTDPELAALLAERRSRP
                     LPASEGEHLTLSAHLTLLREAGFRHAGPVWQFGNSHVVVAVR"
     gene            complement(3506..4057)
                     /locus_tag="STRMOE7_RS19140"
                     /old_locus_tag="STRMOE7_19110"
     CDS             complement(3506..4057)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092320.1"
                     /locus_tag="STRMOE7_RS19140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19110"
                     /product="transglycosylase family protein"
                     /protein_id="WP_084771987.1"
                     /transl_table=11
                     /translation="MPSPLAKRSVVTMLSVLLAVLSVLGLAAPAVAAGAPLGSPVPDWE
                     RIAACESNGRWHINSGNGYHGGLQIDPTTWRAYGGGQYAPRADLATRDEQIAVARRIVR
                     DRGMSAWPNCSYTTGTRAVPRHAPAAAHTYVVRPGDCLSAIAERTHTPGGTKALYHLNK
                     HRLPDGADHIYPGQRLRLRT"
     misc_feature    4283..4299
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 18.83"
                     /tool="antismash"
     gene            complement(4301..5110)
                     /locus_tag="STRMOE7_RS19145"
                     /old_locus_tag="STRMOE7_19115"
     CDS             complement(4301..5110)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STRMOE7_RS19145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STRMOE7_19115"
                     /product="4-phosphopantetheinyl transferase family protein"
                     /protein_id="WP_084771988.1"
                     /transl_table=11
                     /translation="METNAALLELCPEPLDQDVPDPRHHLVRTSPAPLAPAPSTAHPHR
                     HDHPDAAAVPVPIFVVPLASPTAPSAVSAVSSAPDGSTGLLSPDNCLGLNGHSRATLDA
                     ASRNWLLARLPDRVATAMAAATHWELYGTRGLLVVACGEDARRMGFSVESVRRETAAPS
                     TPYEVLTAREAQLAAICPAAERERLITRFWVRKDAAMQAVGRGLSIAPERIEAGFSTDR
                     GTVSVPGPYGLEVPVSVRNFAFADSYEFAVATAEPLPIAPSFAYSVT"
     misc_feature    complement(5097..5108)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 21.4"
                     /tool="antismash"
     gene            5437..6633
                     /locus_tag="STRMOE7_RS19150"
                     /old_locus_tag="STRMOE7_19120"
     CDS             5437..6633
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="STRMOE7_RS19150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19120"
                     /product="histidine kinase"
                     /protein_id="WP_084771989.1"
                     /transl_table=11
                     /translation="MGFFAGCLILYVVGGPRVMGGDITAWQAVLPVLVLCAATAFRSTL
                     PPLAVAVGTVTVLVEMTSSGGLGPVLIYTDLLYAAALYGASWLCRLLQFGTVAVTLATT
                     VALIALGNRSEGVTTGVIVALLLISPVWTGVLIRNHKERADAERERAAQINRLAELDRK
                     TVLQTERTRMARELHDLVANHLSAIAIHSSAVLSLSEAKREQEGGRDGGGEDDPVLRAL
                     AVIRENSVQGLAEMRRMVVLLRSDRGVDDDWDRPQLNALGALVEQARPAADAAALTLHT
                     DFPESFPEVSSVIEVTAYRIVQEALTNVLKHASAGRVRIRCEAGAEQLTISVDSPLARP
                     DGRARPRPVAQLTTGAGAGLAGMSERAALVGGIFDAGPDRTAPGRWRVRAVLPLTQNA"
     gene            6787..7467
                     /locus_tag="STRMOE7_RS19155"
                     /old_locus_tag="STRMOE7_19125"
     CDS             6787..7467
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092317.1"
                     /locus_tag="STRMOE7_RS19155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19125"
                     /product="response regulator transcription factor"
                     /protein_id="WP_107487556.1"
                     /transl_table=11
                     /translation="MRVLVADDQAAVRSGLVLVLQTDPGITVVGEAGDGEAAVRMAAEL
                     RPDVVLMDVQMPLLNGVAATRRIVERGLAEVLVLTTFDLNEYIFGALRAGAGGFILKNA
                     EPAVLVSAVREVAHGDGFLTPSIARRLITEFSGRLPAAGPALPAGAGLPDDTTQALESL
                     TKRELEVLACIARGLPNSAIAETLSLAEGTVKTHISRILSKLHLRSRVQAAILAQQYGI
                     ASRG"
     misc_feature    7201..7203
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7511..9355)
                     /locus_tag="STRMOE7_RS19160"
                     /old_locus_tag="STRMOE7_19130"
     CDS             complement(7511..9355)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024846.4"
                     /locus_tag="STRMOE7_RS19160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19130"
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="WP_084771991.1"
                     /transl_table=11
                     /translation="MNPQVGPARSLCVIGCGPRGTSIVERILANVPALYGDRPLDLHLV
                     DPYPPGAGRTWRTDQPGLLWMNSAAGHVTLYPDESVDCAGPPRPGPTTAGWLDAPLHDG
                     AYAARRDQGRYLRHFFDTVTRERPATVRLYVHRARAVDLRRVTADGLPPAPGEQPGGTP
                     AGRQQVILDSGEPPFLADRVVLAQGHPETRTDPAPPGLTRIGPGPADPDALAAVPPGEP
                     VLVRGLGLVFIDCLALLTEGRGGRFVRTAPGEPLRYLPSGREPRLYAGSRRGVPLPPKP
                     ARGAPDDPAAPPAAPRFATLDACRARLARPAAAFGRDVWPLVLAELGWCHYRALFAEQP
                     ARTRMSRQDFEDQYALLHTDPERLAKLAREAVPDPADRLDLDRLADPLAGLRFDRADDL
                     QRQVRGHLAEVLRRRTGPARRVATALVDGLQRAGAVIEELWRAGDLAADQVSEALGLFA
                     IGTHLSSGPPPLRAEQLLALAEAGVVTFVGPGMRVETATAGRRTVYRATSPALPGVAHE
                     AAVLLDARLAAPAPERAADPLLRALLSRGELAVERTADGAASGMLRLSGAGLHPVGADG
                     TEQRDRIVAGPAQFPRPGTNAVYFRQNDAIARRLLGDD"
     misc_feature    complement(9416..9425)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            complement(9705..9863)
                     /locus_tag="STRMOE7_RS38020"
     CDS             complement(9705..9863)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STRMOE7_RS38020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="class III lanthipeptide"
                     /protein_id="WP_158541811.1"
                     /transl_table=11
                     /translation="MSRNGTWYVTTVHPRLVIGRRCRQMTIMDLQGLEVPGERDAQALG
                     STISGGC"
     misc_feature    9989..10004
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.7"
                     /tool="antismash"
     gene            complement(10001..12682)
                     /gene="lanKC"
                     /locus_tag="STRMOE7_RS19165"
                     /old_locus_tag="STRMOE7_19135"
     CDS             complement(10001..12682)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="STRMOE7_RS19165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19135"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_084771992.1"
                     /sec_met_domain="micKC (E-value: 2.5e-231, bitscore: 768.9,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.8e-08, bitscore:
                     31.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDGAESFALADRTFFDWPGNWDLEATRFPAPPLPDGWTHDENEA
                     WAFCRPPEDRLPDQGWKIHVSAAPDDAPRTIADVAAYCTRHGLTFKYLKSANVLRALSR
                     KYAQRSSAGKLLTVYPVDEAELARTLEGLDALVGGRPGPYVLTDLRFREGPLYVRYGGF
                     RTHFTEDADGELVTAFHRPDGTPEPDRRTPVFHTPDWVTVPDVLKESLAARQALDDFPY
                     RITGALQFSNGGGVYRAAPLGPDALGAGETSVVLKEGRPWSGTDGVGRDAVTRLAHEHR
                     MLQRLAGLPGIPRTYGTLQVRDHLFLVLEDIDGQDFQTWLAAHHPLTVPDPDEQAVAHY
                     RDRALALFGRIEALVAAVHGRGVRIGDLHPGNLIIRPGDEPVLLDFEVADELDRATPSS
                     LGAPGFHRADATGADGDHYALAAIGLWLFLPLAALGGLAPDKAPALLATAAERYALPDA
                     LVARLAPQLAPNDDTTSELRSLPGTFPPTDVLASLGRGLRESATPHRTDRLFPGDFEQF
                     VEGGAGFGHGAAGVLWTRHTVLGERDEEGAAWLRAAVDRVPAERIGFYDGLHGMAYVLR
                     ELGDDEAAQRALDRAADRIPVRHCPSLYRGLSGVGLNLLHFADALDRPDLRQQALDLAG
                     RVTDRLTAARTEPVERRRRRGAQDAAGLMYGWSGAALFLLRAHQATGDPGLLDQAVLAV
                     HRDLDRCSPGPQDTLQVDEGFRLLPYLDNGSAGIALVAAALLDHRDDDRIQRALPALLR
                     ACAADFVIESGLLGGRAGLLATLAALRERAALPPERTDRYLRRHLTNLGQHAMTRNGAV
                     VFPCDGRARISMDLAGGGAGVLLALSTTERGTPLLPFLTDSRPAAAVHPAAPGRVDGAH
                     GAVTPTAPSGAAGTAHHGREVS"
     misc_feature    complement(10958..10960)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12679..13416)
                     /locus_tag="STRMOE7_RS19170"
                     /old_locus_tag="STRMOE7_19140"
     CDS             complement(12679..13416)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="STRMOE7_RS19170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19140"
                     /product="GNAT family protein"
                     /protein_id="WP_084771993.1"
                     /transl_table=11
                     /translation="MQGRLVTLEWPGDDDWAAIASWLRPGSPAAVLSGDWELLGAAEIE
                     QANRSGRVHNLVIRAKDGERIGTVSYQRSGRIGGYTVGGAIGSPELWRRGYGAEAVVLL
                     VDYLFHQLDAHKVQVTTAGYNKGIIRLMTKTQFVVEGILRDHCYLDGEYHDAIVWGLLR
                     DEHYASLKPSDDNRVLAVGLADFVSEDDKTQARAVLAEHLAATGRTALAPYLDAAAPRP
                     AVVPADPSDAAGHGEPAPARGAA"
     gene            complement(13448..14707)
                     /gene="fabF"
                     /locus_tag="STRMOE7_RS19175"
                     /old_locus_tag="STRMOE7_19145"
     CDS             complement(13448..14707)
                     /EC_number="2.3.1.179"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (9-416). E-value:
                     1.4e-60. Score: 197.3. Matches aSDomain:
                     nrpspksdomains_STRMOE7_RS19175_PKS_KS.1"
                     /codon_start=1
                     /gene="fabF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016578549.1"
                     /locus_tag="STRMOE7_RS19175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19145"
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="WP_084771994.1"
                     /sec_met_domain="t2fas (E-value: 1.6e-146, bitscore: 487.0,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 8e-53, bitscore:
                     178.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELRTDRRRVVVTGCGVVSPVGNTTEDFWNALLDGRSGIRAVTRF
                     DASGLPVRIGGELTGFDTTGCLTPQEARRSDNFTQYAVVAAVQAMRAAGLETPAGIDPY
                     RFAVVIGSGYGAAIAIQQQYDVLREHGPRRVSPYHSVLTAIDHPAGLLSIKYGISGPSC
                     AVSAACATGAVAIGEAVEMIRHGRADLALAGGTDDSLTAVDLAGTANAQALSRRNDDPE
                     GASRPFDRDRDGFVMSVGATVLTLEEAGHAERRGAEILAEVAGYAATTDAHHATAPDPT
                     GAGAVRAMRGALADAGCTPEDVGQVSAHGTGTVLNDRIEAAALREVLGPDQLRRTPITA
                     VKSMTGHMLGASGAAEAAAAVLSLRDRVIPPIRNCDHPEEEDLDLVVKGAREWDGDVVL
                     SNSFGFGGHNAVLVLKRWTR"
     aSDomain        complement(13460..14680)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STRMOE7_RS19175_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.40E-60"
                     /label="STRMOE7_RS19175_PKS_KS.1"
                     /locus_tag="STRMOE7_RS19175"
                     /protein_end="416"
                     /protein_start="9"
                     /score="197.3"
                     /tool="antismash"
                     /translation="VVVTGCGVVSPVGNTTEDFWNALLDGRSGIRAVTRFDASGLPVRI
                     GGELTGFDTTGCLTPQEARRSDNFTQYAVVAAVQAMRAAGLETPAGIDPYRFAVVIGSG
                     YGAAIAIQQQYDVLREHGPRRVSPYHSVLTAIDHPAGLLSIKYGISGPSCAVSAACATG
                     AVAIGEAVEMIRHGRADLALAGGTDDSLTAVDLAGTANAQALSRRNDDPEGASRPFDRD
                     RDGFVMSVGATVLTLEEAGHAERRGAEILAEVAGYAATTDAHHATAPDPTGAGAVRAMR
                     GALADAGCTPEDVGQVSAHGTGTVLNDRIEAAALREVLGPDQLRRTPITAVKSMTGHML
                     GASGAAEAAAAVLSLRDRVIPPIRNCDHPEEEDLDLVVKGAREWDGDVVLSNSFGFGGH
                     NAVLVLKR"
     CDS_motif       complement(14183..14230)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STRMOE7_RS19175_0001"
                     /evalue="3.70E-02"
                     /label="PKSI-KS_m3"
                     /locus_tag="STRMOE7_RS19175"
                     /protein_end="175"
                     /protein_start="159"
                     /score="7.1"
                     /tool="antismash"
                     /translation="GPSCAVSAACATGAVA"
     misc_feature    14863..14874
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.94"
                     /tool="antismash"
     misc_feature    14890..14904
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.38"
                     /tool="antismash"
     gene            15139..15318
                     /locus_tag="STRMOE7_RS19180"
                     /old_locus_tag="STRMOE7_19150"
     CDS             15139..15318
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538451.1"
                     /locus_tag="STRMOE7_RS19180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19150"
                     /product="DUF5708 family protein"
                     /protein_id="WP_033267993.1"
                     /transl_table=11
                     /translation="MKGIAVGIVLAIVGLILWLTTKEVETPVVSLHKAGLVLAIVGGAE
                     ALFALLGLGKKANK"
     gene            complement(15377..16624)
                     /locus_tag="STRMOE7_RS19185"
                     /old_locus_tag="STRMOE7_19155"
     CDS             complement(15377..16624)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="STRMOE7_RS19185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19155"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_084771995.1"
                     /transl_table=11
                     /translation="MPELADTGRRIKELRVSAGMTQHDLAGAEMSSSYISLVERGKRIP
                     SGRALRILAERLGVGVDEISRGAEPVETTSRVRRLDLVGRLVAARRQWEGGDAEGALSE
                     FRALAEIDPAGRQDDVFTEAQLAIAEILGTLGRADEGADVLLRMLDALAPAPYAEARLR
                     ALIALADLLESAGRVQDGLRYALTGFLECADRSPGSGFHALLVLEVLTRCAYWSGCPDW
                     APGTDHGRPSADGVLPGPRATIDLHRALDLRDRGEVARAAELLGECARRVTPAAGFPLW
                     EKISGHYALLLLERGETAAARSIVERGLVVASVAQEPDFPLWLSTAEAVCAQAAGDPDR
                     LFALGEEIAALPDTGRSHEKAAALGEIAAACERTGDRERAAGHFRYSAELFRRAQAYRH
                     AERARERLADLLEKRG"
     misc_feature    complement(16613..16628)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.44"
                     /tool="antismash"
     misc_feature    16707..16722
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.8"
                     /tool="antismash"
     misc_feature    complement(16718..16733)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.82"
                     /tool="antismash"
     gene            16961..17617
                     /locus_tag="STRMOE7_RS19190"
                     /old_locus_tag="STRMOE7_19160"
     CDS             16961..17617
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021443.4"
                     /locus_tag="STRMOE7_RS19190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19160"
                     /product="DUF1707 domain-containing protein"
                     /protein_id="WP_084776245.1"
                     /transl_table=11
                     /translation="MTQPQRPDLHKDLAPPSASTRSVLASDAEREDMVERLREATAEGR
                     LTLEELAERSEAAYLARTREELSSVGEDLPHVTAPESARTATGQRSFRAAFGDITHHSP
                     SLEHGIEATAVFGDLTLDLCASPAPSTGELTIQARAIVGDVHLLLPEGVRVEMNCSTVL
                     GDVRNLIREHSGPEAITPRVRITGSAVFGDIIVAHPSSDRRTYWQRWLDERRGRA"
     gene            17692..18444
                     /locus_tag="STRMOE7_RS19195"
                     /old_locus_tag="STRMOE7_19165"
     CDS             17692..18444
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007263794.1"
                     /locus_tag="STRMOE7_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19165"
                     /product="ABC transporter permease"
                     /protein_id="WP_084776246.1"
                     /transl_table=11
                     /translation="MVRHTGALVRRNLLQIRQNPESMTDALLMPIVLTVLFVFVFGGAV
                     GGSRARYTAFLVPGLMVILGMTIAMAVGTGVNDDFRTGLMDRFRTMPIARSSVLLAKIV
                     VETGRMLVALAVLLLVAAVLGFDFTGRWPGIAAAVALTTVFGTSLIWIFMLLGLTLRSA
                     QAIQGLSVLVLTPLQFGSSIFVSPTTMPDWLQTFTRINPLTHMADAARGLILGTGPVAG
                     PVLWTLAWSLTLTAVTAPLAVAKFRSKT"
     gene            complement(18783..20492)
                     /locus_tag="STRMOE7_RS19200"
                     /old_locus_tag="STRMOE7_19170"
     CDS             complement(18783..20492)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981568.1"
                     /locus_tag="STRMOE7_RS19200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19170"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_084771996.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.5e-43, bitscore:
                     147.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-17, bitscore:
                     60.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTHPTAWAALADYLRHLGSGPVFGLPGDDMALLGELERADTP
                     VVLCRDQRNALFMATGYALAAGRPGVCVIGKGPALTNALTGVLEARSAAAPLILIADGT
                     RLDRLGTGAFQELDQLTAVRPYVKWAARIDHADRLPGALEKAAALAVNGTPGPVYLELA
                     EQVADQQVTRSGPWRPVAPQRPTPDQDALAATAERIAAAERPLLLVGGGARHRNTGRRI
                     ERLAERLGAGVFTTASGRGAVAEDHPLYCGVSGLYTVAPMDALWRKADLVIALGSRLEE
                     TATFGWPEDAAQLPVIQAVVSEESLVMERPGAHVLGDAGRIVDGWAALLAGHRATGDWS
                     ERIRTARTALAQRAADRAEEAVKRVPEGAVPVSQVLTALDRAVPADRVLVQENGLQDMW
                     SYFFPHYVLGTGGGSVVPSEQTPLGFGAAAAVGVRLAEPAGRPVVAVVGDGAFNLFRCE
                     LPTVADAGAAVLYLVLDNGGYGWLQSNLDRVSGPASRFSFTTPRPTGTEGVALAHGLGY
                     TRVTHPDDLPAALSTAWQRVASGTTAIVEIAVALPDTPPGMTAASGDFPLRE"
     gene            complement(20489..21730)
                     /locus_tag="STRMOE7_RS19205"
                     /old_locus_tag="STRMOE7_19175"
     CDS             complement(20489..21730)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981569.1"
                     /locus_tag="STRMOE7_RS19205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STRMOE7_19175"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_051733230.1"
                     /sec_met_domain="Aldedh (E-value: 2.2e-24, bitscore: 84.6,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSAPAWPTVAAEPEGSLARHRAAAVHRVRDFLVNDAGTVHELLC
                     EISTHRAARYEIESTVATLDGALDEVAAHRPGRVPRLAAFMPSNVILYSYALYLLVPAL
                     YTDRLVFRPSSRVKDQMRRLHTLLAEQHGLPIELTTASQRDFLHDHVLPADVVVFTGAY
                     ANAEQIRARLSPGQLFLFLGSGVNPFVVAPGADVERAARDAIAIRVLNTGQDCLGPDLF
                     SVHEPLLEPFVDALVSELKGLRYGPYTDPDADFGPIFYDSALEDGAQFLARHRGDIVHG
                     GHVDFRGRRLDPTVVVGEEVTPRTHVPEFFAPIFNVASYRDEDALATTLTTGMFTERAL
                     GSSVYGHAPRLVEALRRRTTVTLDTTLLSIDDGNAPFGGYGRMANYISDGHEVRAEPVL
                     ISKAVAAHRPGAAR"
     misc_feature    21776..21791
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    complement(21777..21793)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.5"
                     /tool="antismash"
     misc_feature    21777..21793
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.61"
                     /tool="antismash"
     misc_feature    complement(21782..21795)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.73"
                     /tool="antismash"
     misc_feature    21785..21798
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.72"
                     /tool="antismash"
     misc_feature    complement(21955..21969)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.24"
                     /tool="antismash"
     misc_feature    complement(21960..21969)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.55"
                     /tool="antismash"
     misc_feature    22098..22113
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.72"
                     /tool="antismash"
     misc_feature    complement(22165..22183)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.59"
                     /tool="antismash"
ORIGIN
        1 ggtgcctcga cgagcagtac tggccgctca caccttctgg gggactcacg gcatgaggta
       61 cgacagcatc accgacgcca tcggcgacac cccgctcgtg cgcatcgatc cggccgtgca
      121 cggcctgcgc cacatcgatc tctacgcgaa gctggagatg ctcaacccct tcggctcggt
      181 caaggaccgg gcggcctgga acatggcccg gcccggcctg cccgacgcgg tgcgccgcgg
      241 cgcgaccatc gtcgagctgt ccagcgggaa caccgccaag gcgctggccg tcatcgcggg
      301 gatgcacggg ctgtcgttca agagcgtcac caaccggatg cgggtgccgg agatcaagga
      361 gctgctcctg ctgctgggcg cggagatcga ggagctgccc ggccggagcg agtgcctcga
      421 cccgaccgac accgaggacc cgctcaccct cttccaccag gaactggccc ggcccggcca
      481 gccgagcctg cacaccgacc agtacttcaa cgacctgaac accgcggcgc acgcggccgg
      541 caccggcccg gagatcatcg ccgacctgga cggccgggcc cccgactggt tcctcgcctg
      601 tgtcggcacc gccggctcgt ccaccggcgt ggccagggcg ctgcgggcgc acgatcccgc
      661 ggtccgggtc gtcgggctgg tcggcgagaa gtccgacttc atcccgggga tccgcaccct
      721 cgacgaggta cacgaggtcg gcctcttcga ccccgccacc tacgacacga tcgaggcggt
      781 cggcgccgac gacgccctgg acgggatgct gacgctgatc cgccgctgcg gtctgctcgc
      841 cgggcccacg ggcggcgcgg cgtaccacgg cgcggtgcgc catctgcggc cgctggacga
      901 cggactggcc gcggaggcgg gcgcggacgg ccgccggcgg accgccgtct tcatcgtctg
      961 cgaccgcgtc gagagctacc tcagctacat ccgcgaacgc cggccggagc tgctgggccg
     1021 gccgcccgcg cggaactcgg tggccaccct caccgacgcc gagatacggg cgacgaccgt
     1081 catcgacacc accgacgccc ggaagtggat cgccgccgaa cgccccctgg tggtcgacct
     1141 ccgcggcccc ttcgcctacg ccgcgctgca catcgacggc tcggtcaaca tcgtggacga
     1201 gctcttcgac gaactcctgc gcggcgggct gccgttcagc aagcggcagc cggtgctgct
     1261 ggcctgtccg gtcggcgaga agtccgtacg gtacgcggcg ctgctgacgc ggatgggcca
     1321 ccccgacgtc cgcagcctgg ccggcggcat catcgcctgg cgcgacgcgg gcgctcccct
     1381 ggtgcgggac tgacatgggc cgtcccgtgg aggacccgcc ccggcggcag gcgccggacg
     1441 acgacctggc ggagctgcgg gcgtggcagc gtccgctgcg cgcccagttc ccgatcatca
     1501 cggcccaccc cggcctcgcc tatctggaca gcgcggccac cgcgcagaag ccgcaggccg
     1561 tcctggacgc cgtgctctcc tacctcacca cctccaacgc caacgcgggc cgcggcacct
     1621 acccctgggc caacgccacg acggccctgg tggaggcggc ccgcgaccgc gtcaagtcct
     1681 tcctgcacga cccgcgtccc gagcgctcga ccgtccactt caccagcggc accaccgagg
     1741 gactgcgcac cgtcgcccgg gactggctgg ccaccttcct gaccgacggc gacgagatcg
     1801 tcgtcccctt cgccgaccac gaggcgaacc tggcgccgtg gctggaggcc cgggacctgc
     1861 tggcgcggcg cggcatccgt gtccgggtcc gcgccctccc ctgccaggag ggctccggcg
     1921 actacgaccc ggcggcgctg gcggcgcagc tcaccccgcg cacccgcttc gtcgccgtca
     1981 cgcacgtgca ccacgtctac ggcgccgaca tgaacgtcca ccgcatccgc gaggtggccg
     2041 ggcccgccgt accgatctgc ctcgacgccg cccagagcat cggtcacctc ccggtctcca
     2101 ccgccgaact ggacgtggac ttcgtggtgt tctccgggca caaggcgctc gccccgccgg
     2161 gcaccggcgt cgtctgggcc cgcggcctgc gcggcccccg cttccgcccc ggcggctggc
     2221 agggcacccc caacaccgcc gggatcgccg gtctggcggc ggcgctcgac tggctggacg
     2281 cggcgggcac ggaccggatc gagcgctgga cggtggcgct ggccgcccgg ctgaccgacg
     2341 gcctcggccg gctcgacgcg tacgagatcc tcggctgccg ggagagcctg tccgccgcct
     2401 cgcgggtcca gcgccgccgc agcatcgtca ccttccggca ccgcggcatc agctccaccg
     2461 acctcggctt catcctctac agccacggct tcatggtccg ctccgaccac cactgccagg
     2521 ccggcgcgca ggacggcgcg caggacggct ccgtgcgggt gagcctgcac gtccacaaca
     2581 ctcccgaaga gatcgacgcg ctggtctcca cgctcaccag tctgcaatga ttttcacaat
     2641 catcggtgca agcatgggtg gcgtgtggtg tcggggtcga gcggtacggc agaggtacgg
     2701 agcgacagga gcgtcagcgg cgcgacggcg gcacgctggg tgcggcgctg ggaggcccag
     2761 cagcagcggt acgcggtcga ccgcgaggag cggctcacgg tgatcaccga cgtcgtcgag
     2821 gacgccaccg ccggccgcgc cgcaccgctg gtcgtcgacc tcggctgcgg cccgggggcc
     2881 ctggcggccc ggctggcggc ccggctcccg cacggcgaga tcgtggccgt cgacgccgac
     2941 cccctcctgc tcgggctggg ccgcgcgtac tacgggccgg cggtccgctt cgtcgaggcc
     3001 ctgatcggcc gccccggctg gctcggcgcc ctggccctgg accgccccct ggacgccgcg
     3061 gtctccacca ccgccctgca ctacctcggc gaggccgcgc tgcgccgggt ctaccgcgac
     3121 ctggccgacc gcctgcgccc cggtggcgtc ctggtcaacg gcgaccacct ccggcaggag
     3181 gccggacggc tgtgcgagat cgcccgggcg gtcggccgcc gccgggccga acgccagcgc
     3241 gcctgcggcc acgaggactg ggactcctgg tgggccgccg cgcacaccga ccccgaactc
     3301 gccgccctgc tcgccgaacg ccgcagccgc ccgctgcccg ccagcgaggg cgagcacctc
     3361 accctctccg cccatctcac gctcctgcgc gaggccggct tccgccacgc gggcccggtc
     3421 tggcagttcg gcaacagcca tgtggtggtc gcggtgcgct gaccgcccac cgcctccggc
     3481 gcgtccggcc gggcccggcc ggggctcagg tccgcaggcg cagccgctgg cccgggtaga
     3541 tgtggtcggc gccgtcgggg agacggtgtt tgttgaggtg gtagagggcc ttggtgccgc
     3601 cgggggtgtg ggtgcgttcg gcgatggcgg agaggcagtc gcccgggcgg acgacatagg
     3661 tgtgggcggc ggccggggcg tgccgcggga ccgcgcgggt gccggtggtg taggagcagt
     3721 tgggccaggc ggacatgccg cggtcgcgca cgatgcgccg ggcgacggcg atctgctcgt
     3781 cgcgggtggc gaggtcggcg cgcggggcat actggccgcc gccgtacgcg cgccaggtgg
     3841 tggggtcgat ctgcaggccg ccgtggtagc cgttgccgga gttgatgtgc cagcggccgt
     3901 tgctctcgca ggcggcgatg cgctcccagt cgggcaccgg ggagccgagg ggagcgccgg
     3961 ccgccacggc gggggcggcg aggccgagga cgctcagcac ggccagcagc acggacagca
     4021 tcgtcacgac ggaacgcttg gcgaggggcg acggcatcac gggattcctc cgctgtgctc
     4081 cggcaacgcc gtgaccgcgt gctcgccacg accggtgggc acgcaccaac taacccggca
     4141 atatggtttt cgcccaaccg gcgaagcacg acatgcgcgc gtttcacccg gctgggccat
     4201 tacctgtgcc gtcgcccgcg gtcgccgatg tcaaggcgtg aattcaggcc aggggcaggg
     4261 aattcgccga ggccgcgccg cctgcccggg aaacgggcaa ttacgtgacc gaataggcga
     4321 aggaaggggc gatcggaagg ggttccgcgg tcgccacggc gaactcgtag gagtcggcga
     4381 aggcgaagtt ccttaccgaa acggggactt ccagaccata cgggcccgga acgctgaccg
     4441 tgccgcgatc ggtggaaaag ccggcctcga tacgctccgg agcgatggac agaccgcggc
     4501 cgacggcctg catggcggcg tccttgcgga cccagaaacg ggtgatgaga cgttcccgct
     4561 cggcggccgg acagatggcc gcgagctgcg cctcccgggc ggtcagcacc tcgtacgggg
     4621 tggacggggc ggcggtctcg cggcggacgg actccaccga gaagcccatc cggcgggcgt
     4681 cctcaccgca cgccaccacc agcaggccac gggtgccgta gagctcccag tgggtggcgg
     4741 cggccatcgc ggtggcgacc cggtcgggga gcctggccag cagccagttg cgggacgcag
     4801 cgtcgagggt ggctctggag tggccgttca ggcccaggca gttgtccggg gacagcagac
     4861 cggtggagcc gtcgggcgcg gaggacactg cggataccgc ggacggcgcg gtgggggagg
     4921 cgagggggac gacgaagatc ggtacgggga cggccgccgc gtccgggtgg tcgtgccggt
     4981 gcgggtgggc ggtcgagggt gcgggtgcga gcggtgccgg agaggtccgg acgaggtggt
     5041 gccgagggtc aggaacgtcc tggtcaaggg gttccggaca gagttcgaga agagcggcgt
     5101 tcgtttccac gtactttccg tcctccacag ttgagcggtg ccgaggccgc actgggtgag
     5161 tgacaggccg tcatacaggt gctgtctccc cctttttcgc ctacatcgat cgatacagac
     5221 agcccaaggt ttgcagatcc tccggatcct tcgagtcatc cctcctgctg atgtacgggt
     5281 acatacttcg atgtacggga gaccgaccca aattcgggcg ccagggccaa gagaacgggc
     5341 aacacgcccc agtactgtcc tcgtgtgtgg ttacgccttt tcacaagtac gcacgcgcgc
     5401 cgccgcccca taccgctccg cgacctcaga ttggccgtgg gattcttcgc cggctgtctg
     5461 attctgtacg tggtgggcgg cccccgggtc atggggggcg acatcaccgc ctggcaggcg
     5521 gtcctgccgg tgctcgtgct gtgcgccgcg accgctttcc gcagcaccct gccgccgctg
     5581 gcggtcgccg tcggcaccgt gaccgtgctc gtggagatga cgtcgagcgg cggcctgggc
     5641 cccgtgctga tctacaccga cctgctgtac gcggccgccc tgtacggggc ctcctggctg
     5701 tgccggctgc tgcagttcgg gaccgtcgcc gtcacgctcg ccaccaccgt cgccctgatc
     5761 gccctcggca accgctcgga gggggtgacg accggcgtca tcgtcgctct gctgctcatc
     5821 tcccccgtat ggaccggggt gttgatacgg aaccacaagg agcgggcgga cgccgagcgg
     5881 gagcgcgcgg cgcagatcaa ccggctggcg gagctggacc gcaagaccgt gctgcagacc
     5941 gaacgcaccc gaatggcacg ggagttgcac gacctggtgg ccaaccacct cagcgccatc
     6001 gccatccact ccagcgccgt gctgtcgctg agcgaggcca agcgggagca ggagggcggc
     6061 cgggacggcg gcggcgagga cgacccggtg ctgcgggcgc tggcggtgat ccgcgagaac
     6121 agcgtgcagg ggctggccga aatgcgccgg atggtggtgc tgctgcgctc cgaccggggg
     6181 gtggacgacg actgggaccg gccgcagctc aacgcgttgg gcgcgctggt cgagcaggcc
     6241 cggccggccg ccgacgccgc cgcgctgacc ctgcacaccg acttccccga gagcttcccc
     6301 gaggtgtcgt cggtgatcga ggtgaccgcg taccgcatcg tgcaggaggc gctgaccaac
     6361 gtcctcaagc acgcctccgc gggccgggtg cggatccgct gcgaggccgg tgccgagcag
     6421 ctgaccatct cggtcgacag cccgctggcc cgccccgacg gccgggcccg gccgcggccg
     6481 gtggcccagc tgaccaccgg tgccggcgcc gggctcgccg ggatgtccga gcgggccgcg
     6541 ctggtcggcg gcatcttcga cgcgggaccc gaccgcaccg cccccgggcg ctggcgggta
     6601 cgggcggtgc tcccgctgac ccagaacgca tagggggacg actcccgggg cgacacggct
     6661 ccgggtccgg gacgggggcg gtgaggacga gaggtgggac agccagtgag gcagccggtg
     6721 gaggacagcg tgcaggacgc gacggcggac gtgccgaggg agaggacgga ccggcggccg
     6781 cccggcatac gggtgctggt ggccgacgac caggccgccg tgcggtccgg gctggtcctg
     6841 gtgctgcaga ccgacccggg catcaccgtc gtcggcgagg ccggggacgg ggaggcggcc
     6901 gtgcggatgg ccgccgaact gcggcccgac gtggtgctga tggacgtaca gatgccgctg
     6961 ctcaacggcg tcgccgccac ccgcaggatc gtcgagcgcg gactcgccga ggtactggtg
     7021 ctgaccacct tcgacctcaa cgagtacatc ttcggggcgc tgcgggccgg ggccggcggc
     7081 ttcatcctga agaacgccga gccggcggtg ctggtcagcg ccgtacggga ggtggcgcac
     7141 ggcgacgggt tcctcacccc gtccatcgcc cggcggctga tcaccgagtt cagcggccgc
     7201 ttaccggcgg ccggacccgc actgccggcg ggggccgggc tgccggacga caccacgcag
     7261 gccctggagt ccctcaccaa gcgggagctg gaggtgctcg cgtgcatcgc gcgcgggctg
     7321 cccaacagcg ccatcgccga gaccctcagc ctcgccgagg gcaccgtgaa gacccacatc
     7381 agccggatcc tgtcgaagct gcacctgcgc agccgggtgc aggcggcgat cctggcacag
     7441 cagtacggga tcgcgtcgcg cgggtgaccg gcctggcccg gggggtgcgg ccccggtgcc
     7501 gggcgggcgc tcagtcgtcg ccgagcagcc ggcgggcgat cgcgtcgttc tgccggaagt
     7561 agacggcgtt ggttcccggg cgggggaact gcgccggccc ggcgacgatc cggtcgcgct
     7621 gctcggtgcc gtccgcgccg accgggtgca gccccgcgcc ggacagccgc agcatcccgc
     7681 tcgcggcgcc gtccgcggtg cgctcgaccg ccagctcgcc gcgggacagc agggcgcgca
     7741 gcagcggatc ggcggcccgc tcgggcgcgg gcgccgccag ccgggcgtcg agcaggacgg
     7801 ccgcctcgtg ggcgacaccg ggcagggccg ggctggtcgc ccggtacacc gtgcgccggc
     7861 cggccgtcgc ggtctccacc cgcatcccgg gccccacgaa cgtcaccacg cccgcctcgg
     7921 ccagcgcgag cagctgctcg gcgcgcagcg gcggcggccc cgagctgagg tgggtgccga
     7981 tcgcgaagag gcccagcgcc tcgctgacct gatcggccgc caggtcgccg gcccgccaca
     8041 gctcctcgat gaccgcgccg gcccgctgca ggccgtcgac cagggcggtc gcgacccggc
     8101 gcgcgggtcc ggtacggcgg cgcaggacct cggcgagatg gccgcgcacc tgccgctgga
     8161 ggtcgtcggc ccggtcgaac cgcagcccgg cgagcgggtc cgccagccgg tccaggtcca
     8221 gccggtcggc ggggtcgggc accgcctcgc gggcgagctt ggcgagccgc tcggggtcgg
     8281 tgtgcagcag tgcgtactgg tcctcgaagt cctgccggct catccgggta cgggcgggct
     8341 gctcggcgaa gagcgcgcgg tagtggcacc accccagttc ggcgagcacc agcggccaga
     8401 cgtcacggcc gaaggcggcg gcgggccggg cgagccgggc acggcaggcg tcgagggtgg
     8461 cgaagcgcgg ggcggcgggg ggcgcggccg ggtcgtccgg ggcgccgcgc gccggtttgg
     8521 gcggcagcgg gaccccgcgg cgggagcccg cgtacagccg gggctcgcgc ccggagggca
     8581 ggtagcgcaa cggctcgccg ggggcggtgc ggacgaagcg gccgccgcgg ccctccgtga
     8641 gcagcgccag gcagtcgatg aagaccagcc ccagtccccg gaccaggacc ggctcgccgg
     8701 gcggcacggc ggccagcgcg tccgggtcgg cggggcccgg gccgatccgg gtcaggccgg
     8761 gcggcgcggg gtcggtgcgg gtctccgggt ggccctgggc gaggacgacc cggtcggcca
     8821 ggaagggcgg ctcgccggag tcgaggatca cctgctggcg acccgccggg gtgccgccgg
     8881 gctgctcccc cggcgcgggc ggcaggccgt ccgcggtcac ccggcgcagg tcgacggcgc
     8941 gcgcccggtg gacgtacagc cggaccgtgg cggggcgttc gcgggtgacg gtgtcgaaga
     9001 agtggcgcag atagcggccc tggtcgcggc gggcggcgta ggccccgtcg tgcagcgggg
     9061 cgtcgagcca tccggcggtg gtgggcccgg ggcgcggcgg cccggcgcag tccacgctct
     9121 cgtcggggta gagggtgacg tgcccggcgg cggagttcat ccacagcagg ccgggctggt
     9181 cggtgcgcca ggtgcggccg gcgccgggcg ggtaggggtc gacgaggtgc aggtccagcg
     9241 gccggtcgcc gtacagggcg gggacgttgg cgaggatccg ctcgacgatc gaggtgccgc
     9301 gcgggccgca gccgatgacg cacagggagc gggccgggcc cacttgcggg ttcaactggc
     9361 ctccgtccgt tggccggtgg ccgtgcgaga gtgcccgacg gccgggggac tgacgtcaga
     9421 aaacacaggg gcccggtggc ccgcaccgaa gtgcgggacc accgggcgcc gtgtcagcaa
     9481 ccgccgctga tcgtggagcc gagcgcctgg gcgtcacgct cgcccggcac ctccaggccc
     9541 tgaaggtcca tgatggtcat ctgtctacac ctccttccga gaatcggtga acgtgtgtac
     9601 ggtggtatgc acggtgcgtg gtggagaccg agcaccgtgt gatcaaggtc gtggtgagca
     9661 aacctcgtgt gatcaagcac cgtgtggaca aagggtcagc tggttcagca gccgccgctg
     9721 atggtcgagc cgagcgcctg ggcgtcacgc tcgcccggca cctccaggcc ctgaaggtcc
     9781 atgatggtca tctgtctgca cctccttccg atgacgagtc gcggatgaac ggtggtgacg
     9841 taccaggtgc cgttgcggga cacctggagc cggcgggccg tgcattccgg tgcgcggccc
     9901 gtccggcgtt gcgtcagcag ccgccggaga cggtggagcc gagagcctgg gcgtcacgct
     9961 cgcccggcac ctccagaccc tgaagatcca tgatggtcat ttacgacacc tcccttccgt
    10021 ggtgcgcagt gcccgctgcc ccggacgggg cggtgggggt gacggcgccg tgggcgccgt
    10081 ctacgcgtcc cggtgcggcc ggatgaacgg ccgccgcggg gcgcgagtct gtgaggaacg
    10141 gcagcagcgg ggtgccccgt tcggtggtgg agagcgccag caggactccg gcgccgccgc
    10201 cggccagatc catggagatc cgggcgcggc cgtcgcaggg gaagaccacc gccccgttcc
    10261 gcgtcatggc gtgctggccg aggttggtca ggtgccggcg caggtagcgg tcggtccgtt
    10321 ccggtgggag cgccgcccgt tcgcggaggg ccgccagtgt ggcgagcagt cccgcgcggc
    10381 cgcccagcag gccggactcg atgacgaagt cggcggcgca ggcgcgcagc agggcgggca
    10441 gggcgcgctg gatccggtcg tcgtcccggt ggtccagcag cgcggcggcc accagggcga
    10501 ttccggcgct gccgttgtcc aggtagggca ggagccggaa gccctcgtcc acctggaggg
    10561 tgtcctgtgg gccgggggag caccggtcga ggtcgcggtg gacggcgagc accgcctggt
    10621 ccagcaaccc ggggtcgccg gtggcctggt gggcgcgcag caggaagagt gcggcgcccg
    10681 accagccgta catcaggccg gcggcgtcct gcgcaccgcg tcggcgtctg cgctcgacgg
    10741 gttcggtgcg ggccgcggtc agccggtcgg tgacccggcc ggcgaggtcg agggcctgct
    10801 gccgcaggtc cgggcggtcc agggcgtcgg cgaagtgcag aaggttcagg ccgacgcccg
    10861 acaggccgcg gtagaggctg gggcagtggc gcacggggat ccggtccgcg gcgcggtcga
    10921 gggcccgttg ggccgcctcg tcgtcgccga gctcccgtaa gacgtaggcc atgccgtgca
    10981 ggccgtcgta gaagccgatc cgttcggcgg ggacccggtc gacggcggcg cgcagccagg
    11041 ccgcgccctc ctcgtcgcgc tccccgagga cggtgtgccg ggtccacagg acaccggcgg
    11101 cgccgtgtcc gaagcccgcg ccgccctcga cgaactgctc gaagtcgccg gggaagagcc
    11161 ggtcggtacg gtgcggggtg gcgctctcgc gcagcccgcg gcccagggag gccagcacgt
    11221 cggtgggtgg gaacgtcccc ggcagggagc ggagttcgga cgtggtgtcg tcgttggggg
    11281 ccagctgcgg cgccagccgc gccaccagcg cgtccggcag ggcgtagcgc tcggcggcgg
    11341 tggccagcag ggcgggggcc ttgtccgggg cgagcccgcc gagggcggcc agcggcagga
    11401 agagccacag gccgatcgcg gcgagggcgt agtggtcccc gtccgcgccg gtcgcgtcgg
    11461 cgcggtggaa gccgggggcg cccaggctgc tgggagtggc ccggtcgagc tcgtcggcca
    11521 cctcgaagtc gaggaggacg ggttcgtcac ccggcctgat gatgaggttg cccgggtgca
    11581 ggtcgccgat ccggacgccg cggccgtgca ccgcggcgac cagcgcctcg atgcggccga
    11641 agagggcgag ggcgcggtcc ctgtagtgcg cgacggcctg ctcgtcgggg tcggggacgg
    11701 tcagcgggtg gtgggcggcg agccaggtct ggaagtcctg gccgtcgatg tcctccagga
    11761 ccaggaagag gtggtcgcgt acctggaggg tgccgtaggt gcgcgggatc ccggggaggc
    11821 cggccagccg ctggagcatc cggtgctcgt gggcgaggcg ggtgaccgcg tcgcggccga
    11881 caccgtccgt cccggaccag ggccgtccct ccttgaggac gacgctggtc tcgccggcgc
    11941 cgagggcgtc cgggccgagc ggcgcggcgc ggtagacgcc gccgccgttg gagaactgca
    12001 gcgccccggt gatccggtag gggaagtcgt ccagcgcctg ccgggcggcc agcgattcct
    12061 tcaggacgtc ggggaccgtg acccagtcgg gcgtgtggaa gacgggggtg cggcggtccg
    12121 gctccggggt gccgtcgggg cggtggaagg ccgtgaccag ttcgccgtcg gcgtcttccg
    12181 tgaagtgggt gcggaagccg ccgtagcgga cgtacagcgg gccctcgcgg aagcgcaggt
    12241 cggtcaggac gtacgggccg gggcggccgc cgaccagcgc gtcgagccct tcgagggtgc
    12301 gggccagctc ggcctcgtcg acggggtaga cggtcagcag cttgccggcc gaggagcgct
    12361 gggcgtactt gcggctcagg gcgcgcagga cgttggcgct cttgaggtac ttgaacgtca
    12421 ggccgtgccg ggtgcagtag gcggcgacgt cggcgatggt gcggggggcg tcgtcggggg
    12481 ccgcgctgac gtggatcttc cagccctggt cgggcaggcg gtcctcgggc gggcggcaga
    12541 acgcccatgc ctcgttctcg tcgtgggtcc agccgtcggg gaggggcggg gcggggaagc
    12601 gggtggcttc caggtcccag ttgcccggcc agtcgaagaa ggtgcggtcg gccagggcga
    12661 agctctcggc gccgtctctc atgcggcacc tcgcgcgggg gcgggctcgc cgtggccggc
    12721 ggcgtcggac gggtccgcgg gcaccacggc cgggcggggc gccgccgcgt cgaggtaggg
    12781 cgccagtgcg gtgcgcccgg tggccgccag gtgctccgcg agcacggcgc gggcctgcgt
    12841 cttgtcgtcc tcggagacga agtcggcgag cccgacggcc agtacgcggt tgtcgtcgct
    12901 gggcttgagc gaggcgtagt gctcgtcgcg cagcaggccc cacacgatcg cgtcgtggta
    12961 ctcgccgtcg aggtagcagt ggtcccgcag gatgccctcg accacgaact gggtcttggt
    13021 catcagccgg atgatgccct tgttgtagcc ggcggtggtg acctgcacct tgtgggcgtc
    13081 gagctggtgg aagaggtagt cgacgagcag gacgacggcc tccgcgccgt agccgcggcg
    13141 ccacagctcg ggcgagccga tcgcgccgcc gacggtgtag ccgccgatcc ggccggagcg
    13201 ctggtagctc acggtcccga tgcgctcgcc gtccttggcg cggatcacca ggttgtggac
    13261 ccggcccgag cggttggcct gctcgatctc ggcggcgccc agcagttccc agtccccgct
    13321 gagcacggcc gccggcgagc cgggccgcag ccaggaggcg atcgcggccc agtcgtcgtc
    13381 gccgggccat tccaaggtca ccagtcgtcc ctgcacggtg cgtttacctc cttctctgtg
    13441 gggtgggtca gcgggtccag cgcttcagta cgaggacggc gttgtggccg ccgaagccga
    13501 aggaattgct cagcaccacg tcgccgtccc actcgcgggc gcccttgacg accaggtcga
    13561 ggtcttcttc ctcggggtgg tcgcagttgc ggatcggcgg gatcacgcgg tcccggaggg
    13621 agagcaccgc ggcggctgcc tcggcggctc cggaggcacc gagcatgtgc ccggtcatgc
    13681 tcttgacggc ggtgatcggc gtccggcgca gttggtcggg accgagcacc tcgcgcagcg
    13741 ccgcggcctc gatgcggtcg ttgaggaccg tgccggtgcc gtgcgcgctg acctggccga
    13801 cgtcctccgg ggtgcacccg gcgtcggcga gggcgccgcg catcgcgcgg acggctccgg
    13861 caccggtcgg gtcgggggcg gtggcgtggt gggcgtcggt ggtggcggcg tagccggcga
    13921 cctcggcgag gatctccgcg ccgcgccgct cggcgtggcc ggcctcctcc agcgtcagga
    13981 cggtggcccc gacggacatc acgaagccgt cgcggtcccg gtcgaagggc cggctggcac
    14041 cttcggggtc gtcgttgcgg cgggagaggg cctgcgcgtt ggcggtgccg gccaggtcga
    14101 cggcggtgag ggagtcgtcg gtgccgccgg ccagcgcgag gtccgcgcgg ccgtggcgga
    14161 tcatctcgac cgcctcgccg atggccaccg cgccggtggc gcacgccgcc gagaccgcac
    14221 aactcgggcc gctgatcccg tacttgatgg acagcaggcc cgccgggtgg tcgatggcgg
    14281 tgagcaccga gtggtacggg gagacccgcc gcggcccgtg ctcccgcagc acgtcgtact
    14341 gctgctggat ggcgatggcg gcgccgtaac cggagccgat caccacggcg aagcggtacg
    14401 ggtcgatgcc ggccggcgtt tcgaggccgg cggcccgcat cgcctggacc gcggcgacca
    14461 ccgcgtactg cgtgaagttg tcgctgcgcc gggcctcctg cggggtgagg cagccggtgg
    14521 tgtcgaatcc ggtgagctcc ccgccgatgc ggaccggaag cccggaggcg tcgaagcggg
    14581 tgacggcgcg gattccgctg cggccgtcga gaagggcgtt ccagaagtcc tcggtggtgt
    14641 ttcccacggg ggacaccacg ccgcagccgg tgacgaccac acgccgccga tccgtgcgca
    14701 actccatgaa acccacctcc tgatttcctg ccccgttgtc acgctcgggg cgtcctcatg
    14761 accagaaaga tgacagctga gtcatctgct tgtcaacagt cggtcggaga gtcagcacac
    14821 ccccggtgtg cgactccttc ctcgaccaag ccccgtacca gcgaaaacgc tctcagacgc
    14881 atgactcgca ctgtcacgaa aattgactgt aggggccagt gcagcggcgc cggagggggg
    14941 tgcacagcgg ccgggcggcg cctcggcggg gcccggcggc ccccaggtag gggccggagt
    15001 acatagaaag tgacagacgc cgggtcggaa agtgcctacc tgcggatgat ccgaatggcc
    15061 cggtccgacg ggacgctggt ccgtacaact ggccccgcgg catcgtgcgg ggcaccgtca
    15121 ccagagacga gggaaccgat gaagggtatt gcggtaggta ttgttctggc gatcgtcggg
    15181 ctgatcctgt ggctgaccac aaaggaagtg gagactccag tggtctcgct ccacaaggcc
    15241 ggtctggtgc tcgcgatcgt cggcggcgcg gaggcgctgt tcgcactcct gggccttgga
    15301 aagaaggcta ataaataagc gcgcattggg cgcaataacg gcatttgcgg cgccgtggcg
    15361 ctttctcccg ccggcgtcag ccgcgctttt ccaggaggtc cgccagccgt tcccgggccc
    15421 gctcggcgtg ccggtacgcc tgggcccgcc ggaacagctc cgcggaatac cggaagtgtc
    15481 cggccgccct ttcccggtcc cccgtccgct cacacgccgc cgcgatctca ccgagcgcgg
    15541 cggctttctc gtggctgcgg ccggtgtcgg ggagcgcggc gatctcctcg cccagcgcga
    15601 agagccggtc cgggtcgccg gccgcctggg cacacaccgc ttccgcggtg ctcagccaca
    15661 gcgggaagtc cggctcctgc gccaccgagg cgacgacgag gccgcgctcg acgatgctgc
    15721 gggccgccgc cgtctcgccg cgctccagga gcagcagggc gtagtggccg ctgatcttct
    15781 cccagagcgg gaagccggcg gccggggtga cccggcgcgc gcactcgccc agcagctcgg
    15841 cggcgcgcgc cacctcaccc cggtcgcgca gatcgagcgc ccggtgcaga tcgatggtgg
    15901 cccgcggccc ggggagcaca ccgtccgcgg acggccggcc gtggtcggta ccgggcgccc
    15961 agtcggggca gccgctccag taggcgcacc gggtcagcac ctccagcacg agcagggcgt
    16021 ggaagccgct gcccgggctc cggtcggcgc attcgaggaa gccggtgagc gcgtaccgca
    16081 gcccgtcctg gacccggccg gccgactcca gcaggtcggc gagcgcgatc agggcccgca
    16141 gcctggcctc ggcgtacggg gcgggggcca gcgcgtccag catgcgcagc aggacgtcgg
    16201 cgccctcgtc ggcgcggccc agcgtgccca gtatttcggc aatggcgagc tgggcctcgg
    16261 taaatacgtc gtcctgccgt ccggcggggt caatctcggc cagtgcacgg aattccgaca
    16321 gcgcaccctc ggcgtcgccg ccctcccatt gccggcgggc cgccaccaat cgtccgacca
    16381 ggtcaagccg gcggacccgg ctggtggttt cgaccggctc ggcgcccctg gatatttcgt
    16441 ccacgccgac cccgaggcgt tccgccagga tccgcagcgc ccggccgctg ggaatgcgct
    16501 tcccgcgttc gacgagcgag atgtagctgg acgacatctc ggccccggca aggtcgtgct
    16561 gtgtcattcc cgcgctgacc cgaagctctt tgatacgtcg cccggtgtcc gccagctcag
    16621 gcattcgaca agccctccgg atttcgaacg ttggatgact ccggccggct gtatcaaatc
    16681 ggcgagtcac aatgagtgct gcgcacttta ccaactagtc aagaagaagt cgaccgatat
    16741 tcggattcct tcaccgttct tcaccggccc tccgagatca tttcgccgga ggccctgggc
    16801 gccgtaaaaa ccggctgccg agtacaccga actgtgtgcc ccgccgccac gggtcaacct
    16861 ttcgatgtac taccccacgc cgatgtccgc gcccggtgtg acgtggtccg atgaggcgac
    16921 cgacgtccca cccctgccgg accccgcgga ggcactctcc atgacgcagc cccaacgccc
    16981 cgatctgcac aaggatctgg cgcccccgtc cgcctcgacg cgctcggtgc tggcgtcgga
    17041 cgccgaacgc gaggacatgg tcgagcggct ccgggaggcc accgccgagg gccggctgac
    17101 cctggaggaa ctggcggagc gttccgaggc cgcgtatctc gcccgcaccc gcgaggagct
    17161 gagctcggtc ggcgaggacc tgccgcacgt caccgccccc gaatccgcca gaaccgccac
    17221 cggccagcgc agcttccgcg ccgccttcgg cgacatcacc catcacagcc cctccctgga
    17281 acacggcatc gaggccaccg cggtcttcgg agacctcacc ctcgacttgt gcgcctcccc
    17341 cgccccgtcg accggcgagc tgaccatcca ggcccgcgcg atcgtcggcg acgtccacct
    17401 gctgctcccg gaaggcgtcc gggtggagat gaactgcagc accgtcctcg gcgacgtgcg
    17461 caacctgatc cgggagcact ccggcccgga agcgatcacc ccgcgcgtgc gcatcaccgg
    17521 ctccgccgtc ttcggcgaca tcatcgtcgc ccacccgagc agcgaccggc gcacgtactg
    17581 gcagaggtgg ctcgacgaac gccgcggccg ggcgtgacgg cgtatcaggc ggcgccccgc
    17641 cccgggaccg gcgccccgct caccgacgag ggacggatac gcccgcgggc catggtccgg
    17701 cacaccgggg ccctggtccg gcgcaacctc ctgcagatcc ggcagaaccc cgagtcgatg
    17761 accgacgcgc tcctcatgcc gatcgtgctg acggtgctct tcgtcttcgt cttcggcggc
    17821 gcggtcggcg gctcccgcgc ccggtacacc gcctttctcg taccgggcct gatggtgatc
    17881 ctcggcatga ccatcgccat ggccgtgggc accggcgtca acgacgactt ccgtacgggc
    17941 ttgatggacc ggttccgtac gatgcccatc gcccgctcct cggtgctgct ggccaagatc
    18001 gtggtggaga ccggccggat gctggtcgcc ctcgcggtcc tgctgctcgt cgcggccgtg
    18061 ctcggcttcg acttcaccgg gcgctggccg ggcatcgccg cggccgtcgc actcaccacg
    18121 gtcttcggca cctcgctcat ctggatcttc atgctgctgg gcctgaccct gcgctccgcc
    18181 caggcgatcc aggggctctc ggtgctggtg ctgaccccgc tgcagttcgg ctcctcgatc
    18241 ttcgtgtccc ccacgaccat gccggactgg ctccagacct tcacccgcat caaccccctg
    18301 acccacatgg ccgacgcggc ccgcggcctc atcctgggca ccggcccggt ggccggcccg
    18361 gtcctctgga ccctggcctg gtccctgacc ctcaccgcgg tcacggcacc tttggctgtc
    18421 gccaagttcc gctccaagac gtaggcgcgt cgcttggggg cttcccacgt gtttgtctgc
    18481 ggcaccgcgg tggtttctcg ccgtggcgcc tgcggcgggc cgggtgattg tcgggtgcgg
    18541 tgccgctcct ccggacttcg tcctgcggcg cggcccctcc cgttggggag atggttaaag
    18601 gccggtgggg gcggacgtcg ttactgacgc ccgcccccac cggccttttt cctacccact
    18661 acgggagggg ctggaccgga ggacgaagtc tggagggccg gcaccgcacc cgaccacaac
    18721 ccagcccgcc gcaggcgcaa cggcgagaag gcaccgcggc gagacagaca acaacgtggg
    18781 aattactccc gcaagggaaa gtcgcctgaa gcggctgtca ttcccggggg tgtgtccggg
    18841 agggcgacgg ctatttcgac gatcgcggtg gtgccggagg cgacccgttg ccaggcggtg
    18901 gagagcgcgg cggggaggtc gtcggggtgc gtgacccggg tgtagccgag gccgtgggcg
    18961 agggctacgc cctcggtgcc ggtggggcgc ggggtggtga aggagaagcg ggaggcgggg
    19021 ccgctgaccc ggtcgaggtt ggactggagc cagccgtaac cgccgttgtc cagcacgaga
    19081 tagagcaccg cggcgccggc gtccgcgacg gtggggagct cgcagcggaa gaggttgaag
    19141 gcgccgtcac ccaccaccgc gaccaccggc cggccggccg gctcggccag tcgtacgccg
    19201 accgcggccg ccgcgccgaa gcccagcggg gtctgctcgc tgggcacgac ggacccgccg
    19261 ccggtgccca gcacgtagtg cgggaagaag tacgaccaca tgtcctgaag gccgttctcc
    19321 tggaccagga cccggtcggc ggggacggcg cggtcgaggg cggtcagcac ctgcgagacc
    19381 gggacggccc cctcgggcac ccgcttgacg gcctcctcgg cgcggtccgc ggcgcgctgc
    19441 gccagcgcgg tccgagcggt gcggatccgc tcggaccagt caccggttgc ccggtgcccg
    19501 gccagcagcg ccgcccagcc gtccacgatc cgcccggcgt caccgaggac gtgggccccg
    19561 ggccgctcca tgaccaggct ctcctcgctc accacggcct ggatgacggg gagttgcgcg
    19621 gcgtcctcgg gccagccgaa ggtggcggtc tcctccaggc ggctgcccag ggcgatgacg
    19681 aggtcggcct tgcgccacag cgcgtccatc ggcgcgacgg tgtagaggcc gctgacgccg
    19741 cagtacaggg ggtggtcctc ggcgaccgcg ccgcggccgg aggcggtggt gaacacgccg
    19801 gcgccgagac gctcggcgag ccgctcgatg cgccggccgg tgttgcggtg ccgggccccg
    19861 ccgccgacca gcagcaacgg ccgctcggcg gcggcgatgc gctccgcggt ggcggcgagc
    19921 gcgtcctggt cgggggtcgg ccgctggggc gcgaccgggc gccaggggcc gctgcgggtg
    19981 acctgctggt ccgcgacctg ttccgcgagc tccaggtaga cggggccggg ggtgccgttg
    20041 acggcgagcg cggcggcctt ctccagggcg ccgggcagcc ggtcggcatg gtcgatgcgg
    20101 gccgcccact tcacgtacgg gcggaccgcg gtcagctggt cgagctcctg gaaggcgccg
    20161 gtgcccagcc ggtcgagccg ggtgccgtcg gcgatcagga tcagcggggc ggcggccgac
    20221 cgtgcctcca ggacgccggt gagcgcgttg gtcagcgccg ggcccttgcc gatcacgcag
    20281 acgccggggc ggccggcggc gagcgcgtaa ccggtggcca tgaacagggc gttgcgctgg
    20341 tcgcggcaga gcacgaccgg ggtgtcggcg cgctccagct cgccgagcag cgccatgtcg
    20401 tcgccgggca gcccgaagac cggcccgctg ccgaggtggc gcagatagtc ggcgagcgcg
    20461 gcccaggcgg tggggtgggt cgtcgcggtc atcgggcggc tcccgggcgg tgggcggcga
    20521 cggccttgga gatcaggacg ggctcggcgc gcacctcgtg accgtcggag atgtagttgg
    20581 ccatccggcc gtagccgccg aacggggcgt tgccgtcgtc gatggacagc agggtggtgt
    20641 cgagggtgac ggtggttcgc cggcgcagcg cctcgaccag gcgcggggcg tggccgtaga
    20701 cgctggagcc cagggcgcgt tcggtgaaca tgccggtggt gagcgtggtg gcgagggcgt
    20761 cctcgtcgcg gtaggaggcg acgttgaaga tcggcgcgaa gaactccggg acgtgggtgc
    20821 gcggggtgac ctcctcgccg acgacgacgg tggggtcgag ccggcggccg cggaagtcga
    20881 cgtgtccgcc gtgcacgatg tcgccgcggt ggcgggcgag gaactgcgca ccgtcctcca
    20941 gcgcgctgtc gtagaagatc ggcccgaagt cggcgtccgg gtcggtgtag gggccgtagc
    21001 ggagcccctt cagctcgctg accagcgcgt cgacgaacgg ttcgagcagc ggctcgtgga
    21061 cgctgaagag gtcggggccc aggcagtcct ggccggtgtt gaggacccgg atggcgatgg
    21121 cgtcgcgggc cgcccgctcg acgtcggctc cgggcgcgac gacgaacggg ttgacgccgg
    21181 agccgaggaa gaggaacagc tggccggggg agagccgggc acggatctgc tcggcgttgg
    21241 cgtaggcgcc ggtgaagacc accacgtcgg cggggagcac gtggtcgtgc aggaagtccc
    21301 gctggctggc ggtggtgagc tcgatgggca ggccgtgctg ttcggcgagc agggtgtgca
    21361 gccggcgcat ctggtccttg acccggctgg aggggcggaa gaccaggcgg tcggtgtaga
    21421 gggcgggcac caggaggtag agggcgtagg agtagaggat gacgttcgac ggcatgaagg
    21481 cggccagacg ggggacccgg ccgggccggt gggcggccac ctcgtccagg gccccgtcga
    21541 gggtggcgac ggtcgactcg atctcgtagc gcgcggcgcg gtgggtggag atctcgcaca
    21601 gcagctcgtg cacggtaccg gcgtcgttca ccaggaagtc ccggacccgg tgcacggccg
    21661 ccgcacggtg gcgcgcgagg ctgccctccg gctcggcggc cacggtcggc catgcgggag
    21721 cggagctcat atgtccctcc tgggggcgta gtccatggag ggtcagcgtc agccaattgt
    21781 catttattgt caagtaaagt cattgcactc gactggccga tgtgacaagc gactcggctc
    21841 tcgacggctc ccggtcgccc ggccgcaccc cgccccctcg tgcgccacat ggcccggcgc
    21901 gcctctcagc tgtcgtaacg cccacccggc ggcaagggga attccggcgt ccgtaagtga
    21961 caaaaaatga ctccccgggc gagggaacgt tgtccacagg catccccggg cggacggccg
    22021 gtgagtagac tccccgtcat cacgcggcct ccgtccggag ccgtccgtac gtcgtcaccg
    22081 tccgtccacc cctctcaact gcgagcgatt ttcttggtga ttgagcagcc tgctttcggg
    22141 aagcgcgtgc gggagacccg gcgcgctcag ggtctgtcgc aaggggacct cgccggcgac
    22201 gacctctccc ccagctatgt ctcgctggtg gagaacggcc gcagaattcc gggcgcgaag
    22261 atcgcccggt cgctcgccga gcggctcggc acgacggtcg aggcgctcag cgccgccgag
    22321 gagccgggcg accggctgac ccaccggctg ggcctggtcg gccagttggt ggcggctcgc
    22381 gccagtgcgc tggccggcga ctggcccgcg gcgcgccggc agctggagtc cctggtggag
    22441 cagaccggcg gcgccggcca ggacgaggtg cgctgggagg cccgctggga gctggccacc
    22501 gtcctcggcc ggctcgacga accggaccgc cacgaagcgg cgctgcgcca cctcctcgac
    22561 gacccgctca cccgttccgc gcccgtgctg cacgcccggg tcgccgtcga gctggcccag
    22621 ctgctgcgcg ccgcgggccg cctctcggag ggtgtgcgct tcgccgagga ggccgtgcgg
    22681 gt
//
