LOCUS       NZ_CP020557            20912 bp    DNA     circular CON 24-JUL-2024
DEFINITION  Paenibacillus larvae subsp. pulvifaciens strain SAG 10367
            chromosome, complete genome.
ACCESSION   NZ_CP020557
VERSION     NZ_CP020557.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus larvae subsp. pulvifaciens
  ORGANISM  Paenibacillus larvae subsp. pulvifaciens
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 4666454)
  AUTHORS   Dingman,D.W.
  TITLE     Paenibacillus larvae genome sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4666454)
  AUTHORS   Dingman,D.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2017) Entomology, CT Agric Expt Station, 123
            Huntington St, New Haven, CT 06504, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2016
            Assembly Method :: SMRT Pipe HGAP assembly v. February-2016
            Assembly Name                     :: sag10367-hgap-022916
            Genome Coverage                   :: 214.2x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002082155.1-RS_2024_07_24
            Annotation Date                   :: 07/24/2024 02:27:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,275
            CDSs (total)                      :: 5,166
            Genes (coding)                    :: 4,634
            CDSs (with protein)               :: 4,634
            Genes (RNA)                       :: 109
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 532
            CDSs (without protein)            :: 532
            Pseudo Genes (ambiguous residues) :: 0 of 532
            Pseudo Genes (frameshifted)       :: 400 of 532
            Pseudo Genes (incomplete)         :: 184 of 532
            Pseudo Genes (internal stop)      :: 26 of 532
            Pseudo Genes (multiple problems)  :: 72 of 532
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:07:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3561780
            Orig. end                         :: 3582692
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020557.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Dr. Adriana Alippi,
            CIDEFI-CIC, Facultad de Ciencias Agrarias y Forestales, Universidad
            Nacional de La Plata, 1900 La Plata, Argentina.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20912
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="17"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20912
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20912
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10912](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10912
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            382..621
                     /locus_tag="B7C51_RS27895"
     CDS             382..621
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7C51_RS27895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237088966.1"
                     /transl_table=11
                     /translation="MGGGEKGTKKSHLTLMILAAVLVGAALMILSSFMNVKDISHYNEG
                     RGSPRKRSPNRFFPEKKIRRKTASGSMKRLLKAV"
     gene            <588..989
                     /locus_tag="B7C51_RS27900"
                     /pseudo=""
     CDS             <588..989
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02830.1"
                     /locus_tag="B7C51_RS27900"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AG"
                     /pseudo=""
                     /transl_table=11
                     /translation="REYEEAFESRLKELLKKIAGVGEPEVMVNIESTEETVVERNAKES
                     HQTTSEKDTNGVSRNISGITRDGQVVLYQVSGDQKPLVLKYIKPKIRGVLVVAKGAENM
                     TVKRMISEAVERSLDVPAQKISILPKKQS"
     gene            1012..1686
                     /locus_tag="B7C51_RS19095"
                     /old_locus_tag="B7C51_19090"
     CDS             1012..1686
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009674921.1"
                     /locus_tag="B7C51_RS19095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19090"
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_077997166.1"
                     /transl_table=11
                     /translation="MNGKRQTIWLVSMLSLMVLLSAYYLFTEDVGKLKDVTQAQEQPTQ
                     VKVDLSELGKDGEKSETDAAGKKDGKSDTKTEGKDSTASGKQQDDSKAASTDAQVLEKM
                     EQKKTGKEFFDQQLMKRNEVMQKEATRLMEIANDSKKTPEEVSKAEQDLKAIQDTVARV
                     ANVEDSLNKDFKNAVVVQEDNKWKVTVQANKLEKSQAVSIVDRMMKELKIGPEKVVVQY
                     IQ"
     gene            complement(1705..3240)
                     /locus_tag="B7C51_RS19100"
                     /old_locus_tag="B7C51_19095"
     CDS             complement(1705..3240)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019419827.1"
                     /locus_tag="B7C51_RS19100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19095"
                     /product="IS1182 family transposase"
                     /protein_id="WP_083041104.1"
                     /transl_table=11
                     /translation="MLRKTGYEGRSQISMVSLDELVPIDHLVRKIEYAIDFSFIYDLVR
                     DVYCEDNGRPSIDPVVLIKIALIQCLFGVRSMRQTIKEIETNVAYRWFIGYDFSQPIPH
                     FSTLGKNYVRRFRDTGLFEGIFHRILEEAARHGFIEPDVLFIDATHVKASANKNKYVKQ
                     IVQEQSRKYQDQLDEEINQDRALHGKKPFEKKPNVTQKEVKVSTTDPECGLFVKGEKER
                     VFAYSFHTACDRNGFVLGVKVTPGNIHDSQVFEDVLHEVTRVVPAPQAVAADAGYKTPA
                     ICKMLQEQEIRPVLPYTRPKTKEEFFKKHDYVYDEHYDCYLCPANAILSYETTNRAGYK
                     MYRSNPAICQACPFRTQCTESKEAVKRISRHVWAECVEEADHLRHTEENKRIYAERKET
                     IERVFADLKEKHGMRWTTLRGLKRVTMQAMLVFSAMNLKRMATWLWKRGRPSDKFNFVF
                     EIGIKNIKNSRYCSISRDFVFNLRARISRALNVQTKYEMVKRFCLQCCLFQGI"
     misc_feature    complement(3500..3515)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.64"
                     /tool="antismash"
     gene            3528..4025
                     /gene="accB"
                     /locus_tag="B7C51_RS19105"
                     /old_locus_tag="B7C51_19100"
     CDS             3528..4025
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310822.1"
                     /locus_tag="B7C51_RS19105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19100"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_077997167.1"
                     /transl_table=11
                     /translation="MYKLNEIKELLKLMDQTSLQELEIENEGSRILIRKANKTETVVVS
                     ASPVQQPVNPVIPAPALPAEQNQASVQPADQQDSGEQSGTELHKIVSPMVGTFYRSPAP
                     GADAFVSPGTKVGDKTVVCIIEAMKLMNEIEAEVKGEIVDVLVENGQLVEYGQPLFLVK
                     PE"
     gene            4043..5401
                     /gene="accC"
                     /locus_tag="B7C51_RS19110"
                     /old_locus_tag="B7C51_19105"
     CDS             4043..5401
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019532743.1"
                     /locus_tag="B7C51_RS19110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19105"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_083041105.1"
                     /sec_met_domain="ATP-grasp (E-value: 1.7e-07, bitscore:
                     29.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.6e-10,
                     bitscore: 37.9, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFQKILVANRGEIAVRIIRACKELVISTVAVYSEGDQDALHVRL
                     ADEAYCIGPTPVKDSYLNVTNIMSVATLTETDAIHPGYGFLSENADFAEICESCNITFI
                     GPSPEAIARMGDKSEAKRTMKEADVPVIPGSDGLIESVDEAIRLGREIGYPLIIKATAG
                     GGGRGIRIAESEEMLIQQITTAQQEAENAFGNAGVYLEKYLTGMKHIEIQILADKHGNV
                     VHLGERDCSIQRRRQKLIEEAPCPVLSPELREAMGAAAVRAAKAVQYSGAGTLEFLLGP
                     DGQFYFMEMNTRIQVEHPVTEMITGVDLIKEMIHIAEGVPLSFTQEDVVINGWSIECRI
                     NAEDPDRGFMPSPGKVDFYLPPGGVGVRVDSAVYPGYRISPHYDSMVAKLIVWGATRDE
                     AIARMRRALDEFAVDGVHTIIPFHEKLLQHNGFIRGDFDIKFLEEHDINDPES"
     gene            5541..5945
                     /locus_tag="B7C51_RS19115"
                     /old_locus_tag="B7C51_19110"
     CDS             5541..5945
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006039367.1"
                     /locus_tag="B7C51_RS19115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19110"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_023485512.1"
                     /transl_table=11
                     /translation="MTISTDYERTDMGSIQIAPEVIEVIAGLATVEVEGVAGMSGGFAN
                     GIAEFLGRKNLAKGVKVEVGQKEAAVDVSIVIEYGQRIPEVSNNIQQNIKNAIESMTGL
                     SVVEVNVHIHDVHFKTDNATDDDHLVQRVK"
     gene            6060..6620
                     /gene="amaP"
                     /locus_tag="B7C51_RS19120"
                     /old_locus_tag="B7C51_19115"
     CDS             6060..6620
                     /codon_start=1
                     /gene="amaP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014369995.1"
                     /locus_tag="B7C51_RS19120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19115"
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="WP_024095035.1"
                     /transl_table=11
                     /translation="MVKVVDRFLLFIYSLIILAGSAIAVSIGFRIIPAKEVSYFLRDLY
                     SETSYAATAIVVGFVIMLISIRLFYISIRRGNTRSPSIDQRSEYGDIRISLETVENLSL
                     KAAGRTRGARELRSRVHVSEAGLDIVMRAVVDGDQPIPSLTEEMQANVKRHVEEITGIP
                     VAKVSVFIANIVQSQPTFKSRVE"
     gene            6633..6860
                     /locus_tag="B7C51_RS19125"
                     /old_locus_tag="B7C51_19120"
     CDS             6633..6860
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009674922.1"
                     /locus_tag="B7C51_RS19125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19120"
                     /product="DUF2273 domain-containing protein"
                     /protein_id="WP_024095034.1"
                     /transl_table=11
                     /translation="MWKELLREHPGKTVGILGGLLCGIVYLFFGFWDMLIFAFISYLGY
                     YIGKKIDQKEAVFPAQDIWDYLTQKWRMFR"
     gene            6955..7404
                     /gene="nusB"
                     /locus_tag="B7C51_RS19130"
                     /old_locus_tag="B7C51_19125"
     CDS             6955..7404
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010274041.1"
                     /locus_tag="B7C51_RS19130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19125"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_024095033.1"
                     /transl_table=11
                     /translation="MRRRVAREIALQSLYQMTMNEVTAKEAVDSVIDEALHENEGAVDL
                     NGDTSAKPYIHELVEGTLTNRERIDQILSEYLKGWQMDRLSKVDREVLRMAAYEMLYRQ
                     DTPPKVVVNEAIELAKHFGTDESGKFVNGVLGKLIKEMDSLKANL"
     gene            7522..8388
                     /gene="folD"
                     /locus_tag="B7C51_RS19135"
                     /old_locus_tag="B7C51_19130"
     CDS             7522..8388
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009225787.1"
                     /locus_tag="B7C51_RS19135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19130"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_077997168.1"
                     /transl_table=11
                     /translation="MAGQVINGKELVSSIREEIKTEAAKLTEAGIRPGLAVVIVGDDPA
                     SHIYVNNKAKACEQVGIYSKVFRLPEATKQEELLALIQKLNEDNRIHGILVQSPLPSHL
                     NEEEVVDHIDPRKDVDCFHPVNVGNLMIGKPGFLPCTPAGVIEILKRTGIDIAGKHAVV
                     VGRSNIVGKPMALLLLREHATVTVCHSRTPNMEEITRQADILVVAVGKANLIRGHHVKP
                     GAVVIDVGMNRNEHNKLTGDVNFGEAKEICSYITPVPGCVGPMTITMLLKNTLQSAVKH
                     LPPGISE"
     gene            8396..9763
                     /gene="xseA"
                     /locus_tag="B7C51_RS19140"
                     /old_locus_tag="B7C51_19135"
     CDS             8396..9763
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345648.1"
                     /locus_tag="B7C51_RS19140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19135"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_198041902.1"
                     /transl_table=11
                     /translation="MAIKERKILSVKELNRYMKMKLESDSVLQDVWVRGEISNFTHHSS
                     GHMYFTLKDKDSRLKSIMFASQNQRLSFRPKEGTMVLARGNISVYERDGQYQFYVQQMQ
                     PDGMGNLYLAFEQLKKKLESEGLFALERKKPIPKYPKAIGVVTSPTGAAVRDIIITLQR
                     RFPSVPVYLYPVLVQGVQAAPSIAKAIDAMNRDAEVDVLIVGRGGGSLEELWAFNEELV
                     ARSIFASAIPVISAVGHETDFTIADFVADLRAATPTAAAELAVPHKLELQQQLDQYRQR
                     LHQGLLKRLERGRDRLERLRRSPFFVHPRRQLTQQPLERLDRVREQLAFRMQKKLSAAG
                     DCHLRLEKRLSAFNPKEQVVYARRCSDAAGRALILAIQGIYKSNRRELGAVMRQLDALS
                     PLKVMQRGYSLVYDEQEKQLIKSLDQVQIGDVVKIKLTDGRLGCHIWSMEENKDAE"
     gene            9753..10004
                     /gene="xseB"
                     /locus_tag="B7C51_RS19145"
                     /old_locus_tag="B7C51_19140"
     CDS             9753..10004
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019532750.1"
                     /locus_tag="B7C51_RS19145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19140"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_023485507.1"
                     /transl_table=11
                     /translation="MPNEENTVSFEEAIEKLEAIVARLESGDVPLEQAIELYQEGMKLS
                     HLCGKKLEQVEKKIDMLVESEAGLIKKPFEPSLGDKIE"
     gene            10001..10912
                     /locus_tag="B7C51_RS19150"
                     /old_locus_tag="B7C51_19145"
     CDS             10001..10912
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006039360.1"
                     /locus_tag="B7C51_RS19150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19145"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_024095032.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.2e-61, bitscore:
                     204.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSINNMGSIQAYLQTRARQVEEALEGSLPVQWEFPADLRESMLYS
                     LMAGGKRIRPVLVLAAVESFGLAPEKVMPVACAIEIIHTYSLIHDDLPAMDNDDYRRGK
                     PTNHKKFGEAMAILAGDALLTHAFYSVTQAARQGGFSAEQVLAVVEEISVYAGARGMVG
                     GQAADMQGVQGITRLEELEYIHARKTSDLIICSLRAGAILAGADEKQLRALTVFGSCIG
                     MAFQIMDDILDVAGDEAKLGKPVKSDEKQKKVTYPYFIGLKASRDKVKGLTEQGKQALL
                     EANLSNPEYLIGIADYLLQRDR"
     misc_feature    10949..10965
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.69"
                     /tool="antismash"
     misc_feature    11246..11261
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.03"
                     /tool="antismash"
     misc_feature    11700..11709
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            11853..13745
                     /gene="dxs"
                     /locus_tag="B7C51_RS19155"
                     /old_locus_tag="B7C51_19150"
     CDS             11853..13745
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019532752.1"
                     /locus_tag="B7C51_RS19155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19150"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_036658495.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.2e-123,
                     bitscore: 409.8, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.9e-07, bitscore:
                     27.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLDRINQPDDLKGLSLEELEQLSGEIRQFLIEKLSLSGGHLSSN
                     LGIVELTIALHTLYNSPKDKFIFDVGHQSYVHKILTGRKDQFDTLRKYKGMCGFIKRSE
                     SEHDIWEAGHSSTSLSAAMGMAVARDFRGEKDKIIAIIGDGAMTGGMALEAMNHIGHEQ
                     RKMMVILNDNEMSIAPNVGALHNYLTKIRSDKHYRKAKEEVESLLKKIPAIGGTLAKTA
                     EKFKDSLKYLLVSGVWFEELGFKYFGPVDGHNIHQLMETMKQAERVDGPVLIHVVTKKG
                     KGYTPAEKDSHKWHGAGPYKIESGQILKSVGNPMYTEVFGNTLIELAEKDDRIVTITPA
                     MPGGSGLMKFAERFPDRMVDVGIAEQHAATFSAGLATEGLKPVFAVYSTFMQRAYDQIV
                     HDICRPNLNVTFAIDRAGFVGPDGETHQGVFDIGFMRTLPNMVLMMPKDENELRHMMKT
                     ALEYDDGPIAYRYARTNGLGLELDKELRSIPIGSWEVIREGQSAAVLAVGPMVQVAEEA
                     AEQLIKDGIQLRVINARFIKPMDEAMLLQLAQENLPLITLEEGAQLGGFGSGVLEFYAE
                     QGIYGMRIKTMGVPDYFVEHGSIREQRCEVGLTSDNIILQVKSFLSRRHNKRAQ"
     gene            13781..14623
                     /locus_tag="B7C51_RS19160"
                     /old_locus_tag="B7C51_19155"
     CDS             13781..14623
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018755139.1"
                     /locus_tag="B7C51_RS19160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19155"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_083041106.1"
                     /transl_table=11
                     /translation="MAMSDKERIDVLLVEQGYYESREKAKAAIMAGLVFVNEESVDKPG
                     IKISRKEDIRVKGAVHPYVSRGGLKLEKALKLFSIDVTGAVMLDIGSSTGGFTDCALQH
                     GASYVYAIDVGYNQLDWSLRSDERVNVMERTNFRYLTSADLQGPKPNFATIDVSFISLK
                     IILPPLKQILGNFGEVVALIKPQFEAGREKVGKSGVVRDPAVHVQVIEEVVEFAETIGF
                     FMKGLTFSPITGGEGNIEFLVYLACNPEDPLIVKETIQAAAKQVVQESRALRPGNSSS"
     gene            14698..15159
                     /locus_tag="B7C51_RS19165"
                     /old_locus_tag="B7C51_19160"
     CDS             14698..15159
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009674914.1"
                     /locus_tag="B7C51_RS19165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19160"
                     /product="hypothetical protein"
                     /protein_id="WP_083041107.1"
                     /transl_table=11
                     /translation="MQSGDLFVTLLVVTVIVSWLTLRFRRWLDVPVKQNMPIPLAKEPV
                     PEDEVVELLEGAGFNVLSGKMKVPILITVNDTEDLQSRLYLDYFAEKKDKLYVVKKARQ
                     RKPMELTGTSVRDTLLIYQLLYPETDGVLYVDMNQLKIKKITFQLEVQE"
     gene            15156..15602
                     /gene="argR"
                     /locus_tag="B7C51_RS19170"
                     /old_locus_tag="B7C51_19165"
     CDS             15156..15602
                     /codon_start=1
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009674923.1"
                     /locus_tag="B7C51_RS19170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19165"
                     /product="transcriptional regulator ArgR"
                     /protein_id="WP_023485502.1"
                     /transl_table=11
                     /translation="MKGQRHVKIREIITNNEIETQDELVESLRQSGFNVTQATVSRDIK
                     ELHLIKVPLPDGRYKYSMPADQRFNPVQRLKRALADHFVQIDYTENMIVMKCLPGTANT
                     ICALIDNMEWSEIMGSICGDDTVLLIIRNKEQTSHVVNQILSLM"
     gene            15616..17346
                     /gene="recN"
                     /locus_tag="B7C51_RS19175"
                     /old_locus_tag="B7C51_19170"
     CDS             15616..17346
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013916407.1"
                     /locus_tag="B7C51_RS19175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19170"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_083041108.1"
                     /transl_table=11
                     /translation="MLTELSIRNLAVVEYVHLVFRQGFHVLTGETGAGKSMIIDALGLI
                     VGGRSSSELVRHGCDRTEIEAVFELPVSHPVWEVLDKLGIMARTDEQLIIRRDVTAQGK
                     SSSRINGQLVNLTMLREVGNWLVNLHGQHEHQSLLKVEEHIHQLDVYGEREIGKAKADY
                     QKTYNIYIKLRRELSELEENSKQSLQMLDLYRFQIKEIAAAGLKEGEDLWLQDEKRKLS
                     NAEKLYQHVAESYDLIYGGNQGLDAISGVVHKLQDITRLDARQLEPLLEQIQSAFYQLE
                     DAAYQLRDYRDQVEFNPDRLQEIEERLDLIANLRRKYGDDVSEILEYMDKIKRELDLIE
                     NKDEVIQKVKEQLLKQEEELIHKAVRLSSVRKQVAKQLALEIESELKDLHMERTQFEIH
                     IESVPDPKGIEVNGELLKFTREGIDEVEFLMAPNPGEPLRGLSKIASGGELSRIMLALK
                     AIFARMEQIPVLIFDEVDTGVSGRAAQAIAEKLSYLSENCQVFSITHLPQVACMADVHF
                     YIHKEIHDDRTFTKVEDLNENGRIRELARMLGGVEVTDTTLHHAQEMIDMAKVKKTRNV
                     "
     gene            17496..18833
                     /gene="spoIVB"
                     /locus_tag="B7C51_RS19180"
                     /old_locus_tag="B7C51_19175"
     CDS             17496..18833
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018755143.1"
                     /locus_tag="B7C51_RS19180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19175"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_198041764.1"
                     /transl_table=11
                     /translation="MLKKDQIRKWIGLMLVFFVCLVSFSTPFQNFASFPETLRIFSGQG
                     KQLHLTMPVHAQLKVADPNIVQVNGQAQHSFQVNLKNPISLQSGHSGQTEMQLNLFGRI
                     PLKTVKVQVVPDLKVIPGGQTIGVKIKSAGILVVGHHLVTADKGQKISPGEEAKIHVGD
                     YITHINGNPSNDVTKIARIVNEAGKSSKPLDLSITRGNQKLNIKLKPAYDVSEKSYRLG
                     LYIRDSAAGVGTLTFYAPKQGVYGALGHVITDMDTQTPITVGNGEIVHSNVTSIAKSQN
                     GEPGEKHAQIFKDSKVIGNIEKNTPFGIFGNMKQPPDHSFSDKAIPVAFAEEVKEGPAQ
                     IYTVLNGQKVEKFDIEVVHVSKQQYPATKGMVIKITDPRLLEKTGGIVQGMSGSPIIQN
                     GKMIGAVTHVFVNDPTSGYGCFIEWMLQDSGIMLKNTVKPKELKAG"
     misc_feature    18865..18878
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     misc_feature    complement(18866..18879)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.85"
                     /tool="antismash"
     gene            19019..19810
                     /gene="spo0A"
                     /locus_tag="B7C51_RS19185"
                     /old_locus_tag="B7C51_19180"
     CDS             19019..19810
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /GO_process="GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009591253.1"
                     /locus_tag="B7C51_RS19185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_19180"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_036658065.1"
                     /transl_table=11
                     /translation="MQKIQVLLADDNREFTQLLSEFIGEQEDMEVMAVAYNGNEVLRLF
                     EQNEIPDVLILDIIMPHLDGLGVLEKLREMNLTPAPKIIMLTAFGQENITQKAVQLGAS
                     YYILKPFDMEVLTNRIRQLVGNQPSLTSAISNKANIVQMPKGKNLDANITTIIHEIGVP
                     AHIKGYQYLREAITMVYNNIEILGAITKTLYPAIAEKYKTTPSRVERAIRHAIEVAWTR
                     GNIDSISYIFGYTVNISKSKPTNSEFIAMVADKLRIEHKVS"
     misc_feature    complement(20283..20300)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 20.62"
                     /tool="antismash"
ORIGIN
        1 ctaagatcag tagggtcacg gtgcatctct gggactgtcc ccccaacacc agggaccagg
       61 aaaaccagca ggctgaccac agagaagcta ttgctgccat tcgcccagta gaccctgtca
      121 agccggtaga gcctattacg aaaatagata atcagaagtc ttccgaatct gcttccgctc
      181 aggttaaaaa tctcacaaaa gaggaaaagg cacagaaaca aaaagtggag gaactgttag
      241 ttaaacaatg ggagctcgac ccttcgtact tggatgttca aatacaccgt tcaggcagca
      301 aattataaca gaggcggcat gacccgcagg gaagagaggt gacagcatgt gggcaagttt
      361 aagcagtggt tcgacaattg gttgggtgga ggagaaaaag gtacaaaaaa atcccatctt
      421 acgctcatga tcctcgctgc cgtactggtg ggggctgcct tgatgattct gagctctttt
      481 atgaatgtga aggacatcag tcactataac gagggtcgtg gctccccaag gaagaggtct
      541 cccaacaggt tttttccgga aaagaaaata aggagaaaaa cggcttccgg gagtatgaag
      601 aggcttttga aagccgtcta aaagaacttt tgaaaaaaat tgcaggagtg ggcgaacccg
      661 aagtaatggt gaatattgaa tcgactgaag aaactgtcgt agaaagaaat gcgaaagaat
      721 cccatcaaac cacttctgaa aaagacacca atggggtttc acggaatatt tccggtatta
      781 ctagagacgg gcaggtggtg ctgtatcagg tctcagggga ccagaaaccg ttagtgctga
      841 agtacatcaa acctaaaata cgaggagtct tagttgtagc taaaggggct gagaatatga
      901 ctgtaaagcg gatgatctcc gaagccgtgg aacggagtct ggatgttccg gctcagaaaa
      961 tctcaatcct gcccaaaaaa caatcttaaa tgatacgagg aggaacgaag aatgaatgga
     1021 aaaagacaaa caatctggct ggtatcgatg ctgtctttaa tggtactgct atcggcctac
     1081 tatctgttca ctgaggacgt tggcaaactt aaggatgtta cgcaggcaca agaacagccg
     1141 acacaggtga aagtagattt gagtgaactc ggcaaggacg gggaaaaaag tgaaactgat
     1201 gcagcaggaa aaaaagacgg aaagtctgat acaaaaacag aaggaaagga tagtacggct
     1261 tctggcaaac agcaggatga ttcaaaggca gcttccacag atgcccaggt tcttgaaaaa
     1321 atggagcaga aaaaaaccgg caaagaattt tttgaccagc agctgatgaa acgcaatgaa
     1381 gtcatgcaga aggaagctac ccgcctcatg gaaattgcca atgattccaa gaaaactccc
     1441 gaagaagtca gcaaagccga gcaggatctg aaagcaattc aggacacagt tgccagagta
     1501 gcgaatgtag aggatagttt gaacaaagat tttaaaaatg cggtggtagt gcaggaagac
     1561 aataaatgga aagtaaccgt ccaggccaat aaactggaaa aaagccaggc tgtctctatt
     1621 gtagaccgta tgatgaaaga gcttaagatc ggacctgaga aggtagtcgt ccagtacatt
     1681 cagtaaaaag gatttggctt aatgtcagat tccctggaat aaacagcact gtaagcaaaa
     1741 tctttttacc atttcatact ttgtctgtac gttcagagcc cgagatattc gggctctcag
     1801 attgaagaca aagtcccgcg aaatactaca gtagcgggag ttctttatgt tttttatccc
     1861 tatttcaaat acaaaattga atttatcaga tgggcgacct ctcttccaga gccaggtcgc
     1921 cattcttttg aggttcatgg cagaaaaaac aagcattgcc tgcatggtga cccttttaag
     1981 tcctcgtaag gtcgtccacc gcataccatg cttctccttt aaatcagcaa aaactcgctc
     2041 tatggtttct tttcgctctg cgtaaatccg tttgttttct tctgtatggc gaaggtggtc
     2101 cgcctcttcc acacattcag cccaaacatg acgactaata cgcttcactg cctctttact
     2161 ctctgtacat tgtgtccgga aaggacaggc ttggcagatt gccggattcg agcgatacat
     2221 tttataacca gcacggttcg ttgtttcgta agacagtatg gcatttgccg gacacaggta
     2281 gcagtcgtag tgctcatcgt aaacgtaatc atgcttttta aagaattctt ctttcgtctt
     2341 gggacgggta tacggcagga cgggacgaat ctcttgttcc tgcagcattt tgcagatggc
     2401 tggtgtttta taacctgcat ccgcggcaac cgcttgtgga gccggaacta cgcgagtaac
     2461 ctcgtgtaga acatcttcaa atacttggct gtcgtggata tttccagggg ttactttgac
     2521 gccgagtaca aacccgttcc gatcacacgc ggtatggaag ctgtaggcga aaacacgttc
     2581 tttctctccc ttcacgaaca aaccacactc cgggtcagtc gtgctcacct tcacctcctt
     2641 ctgcgtgaca ttgggctttt tttcgaacgg tttctttcca tgtagagccc gatcttgatt
     2701 gatctcttca tcaagctgat cctggtactt tcgactttgc tcctgaacga tctgttttac
     2761 atatttgttt ttgttcgcgc ttgctttaac atgtgtcgcg tcgatgaaga gtacgtcagg
     2821 ttcaatgaaa ccatgccggg cagcttcttc gaggatgcga tgaaagattc cctcaaacag
     2881 tccagtatcc cgaaaacggc gcacgtaatt tttacccagc gtggagaaat gaggaatggg
     2941 ctgactgaag tcatagccaa taaaccaacg gtacgcgacg ttggtttcaa tctctttgat
     3001 ggtctgacgc atggagcgaa caccaaaaag gcattgaata agcgcaattt taataagaac
     3061 aaccggatca atgctagggc ggccgttatc ctcacagtaa acatcccgaa ccaagtcata
     3121 gatgaaacta aaatcgatgg cgtattcgat tttacggacc aaatgatcta taggtacaag
     3181 ctcgtccaag gagaccatgg aaatttgaga acgtccttcg taaccggttt ttcgcaacat
     3241 attcaagcac tcccgcacta gttatttacc tatatgatac tatatgaatg cggtgaatgg
     3301 ttggtgtatt ttcgtaaaaa agactgtcga caggactttg tcgacagtct gagagcccga
     3361 gatattcggg ctctttccat ttctttcgtt tgtgatataa tacataacgt taccgtgaac
     3421 aagctttaga tcattcagtt taggtatgtg ctaagaaacc atccggcacc gtccgggtca
     3481 agtttttttg tttagtttgg ttcacaaatg taaaaggagt gacatggatg tacaaattaa
     3541 atgaaattaa agaacttttg aaattgatgg atcaaacgtc cctgcaggag ctggaaattg
     3601 agaatgaagg ttcccgcatt ctgatccgca aagcgaataa aacggaaact gtggtagtct
     3661 ctgcctcgcc ggtacaacaa cccgtaaacc ctgtcattcc tgcaccagca ttgccggcgg
     3721 aacaaaatca agcatctgtc cagcctgcgg atcagcaaga cagcggcgaa cagtctggaa
     3781 ctgaattaca taagattgta tctccaatgg taggcacttt ttaccgttca ccagctcccg
     3841 gagcagatgc tttcgtgtca ccgggcacca aagtagggga taaaacagtc gtgtgtatca
     3901 tagaagcgat gaagctgatg aacgaaattg aagctgaagt caaaggagag attgtagacg
     3961 ttctggtaga aaatggccag cttgtagaat acgggcagcc attgtttttg gtgaaaccgg
     4021 agtgagttca ggagggaatg caatgaggtt tcaaaagata ttggtggcga accggggaga
     4081 aattgcagtc aggattatcc gagcttgtaa ggagcttgtt atctctacgg tggctgttta
     4141 ttccgaaggg gaccaggatg cactgcatgt gcggcttgcg gacgaagctt actgcattgg
     4201 cccaaccccg gtcaaagaca gctatcttaa cgttacaaat attatgagtg tagctacgct
     4261 aaccgaaacg gatgcaatcc atcccggata cgggtttctt tcggaaaatg cggattttgc
     4321 tgaaatttgc gagagctgta atattacgtt tatcggccct tcccctgagg ctattgcccg
     4381 gatgggggat aaatctgagg caaagcggac gatgaaagaa gcggatgtgc cggtaattcc
     4441 cggttctgac ggactgatcg agagcgtcga tgaagccata cgtcttggaa gggaaattgg
     4501 ttatccgttg ataattaaag ctacggcagg aggcggaggg cgaggtatcc gcattgctga
     4561 gagcgaggaa atgctcattc agcaaatcac gacggcccag caggaagcgg agaacgcatt
     4621 cgggaatgcc ggagtctatc tggagaagta tttaaccggc atgaagcaca ttgagatcca
     4681 gattctggca gacaagcacg gcaatgtagt ccatcttggg gagagggact gttccatcca
     4741 gcgccgcaga caaaaactga ttgaggaagc gccctgtccg gtattaagcc ctgaactccg
     4801 ggaagctatg ggagctgctg ccgttcgtgc cgctaaagcg gtacaatatt ccggggcagg
     4861 tacccttgaa ttcctgctgg gacctgacgg acaattttat ttcatggaga tgaatacccg
     4921 cattcaggta gaacacccgg ttaccgagat gatcacaggt gtggatttaa ttaaagaaat
     4981 gattcatatt gcagaaggtg tcccgttatc ctttacacaa gaggatgtgg tcattaatgg
     5041 atggtctatt gaatgccgta tcaatgcgga agatccggac cgcggtttca tgccttctcc
     5101 aggcaaggtc gatttttatc ttcctccggg aggcgtggga gtacgcgttg acagtgcggt
     5161 ttatccgggt tatcgcattt ctccccacta cgattccatg gttgccaaac tcattgtatg
     5221 gggagctacc agagatgaag ccatcgcacg catgcgccgt gcattggatg aatttgcagt
     5281 agatggtgtg cataccatta ttcctttcca cgaaaaatta ttacagcata acggctttat
     5341 ccgcggtgac tttgacatca agtttttgga ggaacacgac attaacgatc ctgaatcctg
     5401 ataagaattc gattcattgt catatttttg gctaaatggt atagtattaa attagtacag
     5461 cttatccagc tgcgcggacc aggcattggc ttacaaggca agtttgctgt tcgcaaactt
     5521 agaggaggtg tgcacatagc atgacaattt ctacggatta cgaaagaacg gatatgggct
     5581 ccattcagat tgccccggaa gtcattgagg taattgcggg tctggccact gtagaggtgg
     5641 aaggagttgc cggcatgagc ggcggtttcg cgaatgggat tgccgaattc cttggacgca
     5701 aaaacctggc taaaggtgta aaggttgaag tgggacaaaa ggaagctgcg gtcgacgttt
     5761 ccattgtgat cgaatacggc cagcggatac ctgaagtgtc taacaatatt caacaaaata
     5821 tcaagaatgc cattgaatcg atgacaggac tttccgttgt tgaggttaat gtccatattc
     5881 atgatgttca cttcaagaca gataacgcta cggatgatga ccatttagta caacgggtta
     5941 aataatcggg atagtatgga ataaggagaa acccctacta gaagaagaag tgagggggtt
     6001 tccttgccaa tagaaataag aactttagtt actctggcca gaaaggggac aagctacccg
     6061 tggttaaagt tgtagaccgg tttttactat ttatctatag cctgataatt ctagctggtt
     6121 cggccattgc cgtttcaata ggctttcgaa ttattccggc caaagaggtt tcctattttc
     6181 tccgggacct ttattcggag acttcctacg cagcaactgc aattgtggtc ggctttgtga
     6241 ttatgctgat cagcatacgc cttttttaca tatcgataag acgcggcaat accaggtccc
     6301 cttccattga ccagaggtcg gaatacgggg atatccgcat ttcccttgaa accgttgaaa
     6361 atctgtcctt aaaggcagcg gggcgtaccc ggggcgccag agaattaaga tcccgtgtac
     6421 atgtaagcga agccggcctc gatattgtca tgcgggctgt tgtggatggt gatcagccca
     6481 taccatcact gaccgaggaa atgcaggcaa atgtgaagcg gcatgtggag gaaattaccg
     6541 ggattcctgt ggccaaagtc tcggtgttta ttgcaaatat cgttcaatct caacctacct
     6601 tcaaaagccg ggtagaatag ggggacccgc ttatgtggaa agaactctta cgagaacatc
     6661 ccggcaagac agtcggcata ttagggggac tgctgtgcgg aattgtctat ttgtttttcg
     6721 gtttttggga tatgctgata tttgctttta tctcttacct gggttattat atcggcaaaa
     6781 agatagatca gaaggaagct gtttttcctg cccaggacat ttgggactat ttaacgcaaa
     6841 aatggagaat gttccgctga aatccttggt tttgccttgg atttttttgt ttggaaaggt
     6901 ttaagattga cgtatactat aagcaagcgt gtgaaaagtt taggaggccg ttacatgagg
     6961 cgcagagttg cgagagaaat tgctttacaa agtttatacc agatgacaat gaacgaggta
     7021 actgcaaaag aggcggtaga ttccgtcatt gatgaggctc ttcatgaaaa tgaaggggca
     7081 gtggatctga atggggatac ttcagccaaa ccttatattc atgagctcgt agagggaact
     7141 ttgacgaacc gggaacggat cgaccaaatc ctctccgaat atttaaaagg atggcagatg
     7201 gaccgtttgt ctaaagtgga ccgcgaggtt cttcgaatgg ccgcatatga aatgctctac
     7261 aggcaggata cgccgcctaa agttgttgtt aatgaggcga tagagcttgc caagcatttt
     7321 ggaactgatg aatccggaaa gtttgtcaac ggagtactgg gtaagctgat aaaagagatg
     7381 gacagcctga aagcaaatct ctaatctgtt ttttaccgag cgtaatgcct gcaataagga
     7441 aagaagcagt tcccgcttga ccgcagaaag ggaacatgtc agactgattc tatagatatc
     7501 catggtgagg gggaaaccag attggcagga caagttatta acggaaaaga actcgtaagt
     7561 tccattcggg aagaaatcaa gacggaagct gcaaaactga cagaagcggg catcaggccg
     7621 ggattggccg tagtaattgt cggggatgat cccgcttccc atatttatgt caacaataag
     7681 gctaaagcat gtgaacaagt gggcatatac tccaaagtat tccgtttacc tgaagctaca
     7741 aaacaggaag aattgcttgc tttgatccaa aagctgaacg aggacaatcg cattcacggt
     7801 attctggtgc aatccccgct tccgtctcac ttgaacgaag aggaagttgt agatcacatt
     7861 gatccccgca aagacgttga ctgttttcat cctgttaatg taggaaatct tatgatcggt
     7921 aaaccgggat ttcttccctg tacgccggcg ggcgtgatcg aaattttaaa gagaaccggt
     7981 attgatatag ccggcaagca tgcggtagta gtaggacgaa gcaatattgt cggtaaaccg
     8041 atggctcttt tgcttctgcg tgagcatgcg acagttacgg tctgtcactc ccggactcca
     8101 aatatggagg aaatcacccg ccaggctgat attttggtag tggcagtcgg caaggcaaac
     8161 ctgattcgcg gtcatcatgt aaaaccgggt gccgtggtga tagatgtggg catgaacagg
     8221 aacgagcaca ataaacttac cggagatgtc aattttgggg aggccaaaga gatctgcagt
     8281 tatatcactc cggtaccggg ctgtgtagga cctatgacga ttaccatgct gctgaagaac
     8341 accctccaat ccgccgttaa acatctgccg ccgggtataa gtgagtgagc ggacaatggc
     8401 gataaaagaa cggaaaattc tgtcggtcaa ggaattaaac cgttatatga aaatgaagct
     8461 ggagagtgac tccgttcttc aggatgtttg ggtacgtgga gaaatctcca actttaccca
     8521 tcattccagc ggacatatgt attttacatt gaaggataag gatagccgcc tgaagagcat
     8581 tatgtttgcg tcacaaaatc agcgcctgtc ttttagaccg aaagaaggta caatggtgct
     8641 ggcccgtggc aatatttccg tttatgaacg tgatggacaa taccagttct acgttcagca
     8701 gatgcagccg gacggaatgg ggaatttgta tctggccttc gaacagctga aaaaaaagct
     8761 ggaatcggaa ggcttgtttg ccttagagcg caaaaagccc attcctaagt atccgaaagc
     8821 tatcggtgtt gtcacatcgc ctacgggtgc tgccgtacgg gatattatca tcacgctgca
     8881 aagaaggttc ccttcggtgc cggtatacct gtaccctgtt cttgtgcagg gggtacaggc
     8941 ggccccgtcg atcgccaagg cgatcgacgc catgaaccgc gacgctgaag tcgatgtact
     9001 gattgtcggc cggggcgggg gatcgctcga agagttatgg gcgttcaacg aggaactcgt
     9061 tgcccgcagt atcttcgctt ccgcgatccc tgtcatttcg gccgtcggac atgagactga
     9121 cttcaccatc gcagacttcg tcgccgatct gagggcggcg acgccgacag ccgctgcgga
     9181 gttggccgtg ccgcacaagc ttgagctgca gcagcagctc gaccagtaca ggcagcggct
     9241 ccaccagggg ctgctaaagc gactcgaacg cggaagggac aggctggagc ggctgcggcg
     9301 ctcccccttc tttgtccatc cgcggcgcca gcttacccag cagcccctgg agaggctgga
     9361 ccgcgtgcgg gagcagcttg ccttccgtat gcaaaagaag ctttctgcag caggagactg
     9421 ccaccttaga ctggagaaaa ggctatccgc cttcaatccg aaagagcagg tagtctatgc
     9481 ccgaagatgc agtgatgcgg cagggcgtgc cctaatactg gctatacagg ggatatacaa
     9541 gtcgaaccgg cgggaacttg gcgccgttat gcgccaactg gacgcgctca gcccgctgaa
     9601 agtaatgcag cgcggataca gccttgttta tgatgaacag gaaaagcaat taatcaaatc
     9661 gctggatcag gtacagatcg gcgatgttgt aaaaataaaa ctgaccgatg gccggctcgg
     9721 ttgtcatatc tggtcgatgg aggagaacaa ggatgccgaa tgaggaaaac acagtaagct
     9781 ttgaagaagc catagagaag ctggaagcca ttgttgcccg gcttgaaagc ggagatgttc
     9841 ctcttgagca ggccatcgag ctgtatcagg aaggaatgaa actttcccat ctctgtggga
     9901 aaaagttgga gcaggttgaa aagaaaatag acatgctggt agaaagtgaa gccggtctga
     9961 tcaaaaagcc tttcgagcct tccttggggg acaagatcga atgagcataa ataatatggg
    10021 gtctattcaa gcatatttac aaacccgtgc ccgccaggtt gaagaagctc tggaagggtc
    10081 tttgcctgta caatgggagt ttccggctga tctccgggaa tctatgcttt attccttaat
    10141 ggcaggaggc aaacgaatca gaccggtcct cgtacttgca gcggtagaaa gctttggact
    10201 agctcctgag aaggtcatgc cggtagcctg cgctattgaa ataattcata cttactccct
    10261 gattcacgat gatctgccgg ctatggataa tgacgattat cgtaggggca agccgactaa
    10321 ccataaaaaa ttcggggagg ccatggctat tctggcggga gatgctcttc tgacacatgc
    10381 tttttacagc gtgacacaag ctgcccggca aggtggtttt tctgcggaac aggtgctggc
    10441 cgttgttgag gaaatatctg tctacgcagg agcaagagga atggttggcg gacaagctgc
    10501 cgatatgcag ggagtgcagg gtatcacgcg gctggaagaa ctggagtaca ttcatgcccg
    10561 caagaccagt gatctgatta tatgcagctt acgtgcagga gccatacttg ccggggcgga
    10621 tgagaagcag ctgcgtgcgc ttacagtctt cggttcctgt atcggcatgg cctttcaaat
    10681 tatggatgat atacttgacg tggccggaga cgaagccaag cttggaaaac cggtgaaaag
    10741 tgacgagaaa cagaaaaagg tcacctatcc ttattttatt gggcttaaag catccaggga
    10801 taaagtgaaa gggttgacgg aacaaggaaa acaagcgctg cttgaagcaa atttaagcaa
    10861 cccggaatac ttaataggaa tcgctgatta tcttttgcaa agagaccgtt gatcccgcaa
    10921 agggtgtcag cctttggtct gatcattctg cttttaaaac aggccaggcc tgtctatgtt
    10981 agaaatgtca cgaaattatg ttataatgga gtatatctgt tatggagtgg tacagtattc
    11041 tagtcagtct accgtttccg agggcggacc taaaaattag ttaaagggca catcgatgaa
    11101 gttcctgatg ttggcttccg acgcccattt ggggttgatg ctgaatgaaa ccattccctt
    11161 taaaagaggc tgagaaacgg ttaaaggctg cctaagaaag cccctagact gttcatgatt
    11221 atggggcttt ctggggatta tagtgtggac tgagtggtca tctagtctga tggccggcgg
    11281 gcggcatcaa gacagacatg aaggaaaccc ccatttggcg acaaaagggt gtcccgcttg
    11341 ggaaaacctg ctggacctaa gccacagcgt ttactcgcga gccaacactc tgattccatg
    11401 acttttatca tgtttttctt attctcggat gtgttacatt cgtttttgaa gatcccgttt
    11461 tatttccccg tcatgcctgc tgcctttaaa ggagcggctt tgttgtttat tgtttccttt
    11521 tttggacatg ggagttgaaa aatgagattt tcttggaagt actccatcaa atagagtatt
    11581 tttatcaatt gtaactttta ttttagcttg tatatttaat agtcgtttcc accaccatac
    11641 tcgaaggttt tccttggggt atcggaatgc tgattgtttt acttttaatc agttcggtgt
    11701 attttttgat ttaattgacc ttcgttatcc accattcgac ggcaatcgta ctttttatag
    11761 gaaagtattt tatgttatag aaaataaatt cggaatacgc atttttgcta agaaaaagca
    11821 aaaaacacaa agcggaaagc gaggaaacaa gcgtgctgct cgatcgaatc aatcagcctg
    11881 atgatctaaa gggattatcc cttgaagaat tggaacagct gtccggggag atccgccaat
    11941 ttcttatcga aaagctgtcc ctttccggcg gtcatctgtc ttccaactta ggtatagtag
    12001 agcttaccat tgcccttcat acgttataca acagtccgaa agacaagttc atttttgatg
    12061 tgggccacca gtcttatgtc cataaaattt tgacaggtcg gaaggatcaa tttgatacac
    12121 tgcgcaagta taagggcatg tgcggcttta tcaagcgttc ggaaagcgaa cacgatattt
    12181 gggaggcggg acatagcagt acctcgcttt cagctgcgat ggggatggcg gttgcccggg
    12241 attttagagg ggagaaggat aaaattatcg ccattattgg agacggagcc atgaccggag
    12301 gaatggccct tgaagccatg aaccacatag ggcatgaaca acggaagatg atggttatcc
    12361 tgaacgataa tgagatgtcc attgccccga atgtaggtgc tctccataat tatttgacaa
    12421 aaattcgttc cgacaagcat taccgcaagg ccaaagaaga agtggaaagt ctgctgaaga
    12481 aaattccggc tataggcgga acgcttgcca aaacagcaga gaaattcaag gacagcctga
    12541 aatatctgct tgtttccgga gtctggtttg aggaactcgg atttaaatat tttggccctg
    12601 ttgacggtca caatatccat cagctgatgg agacaatgaa acaggctgaa cgtgtggacg
    12661 ggccagtctt gattcatgtt gtgacgaaga agggaaaagg ctatacaccg gctgagaagg
    12721 attcgcacaa atggcatgga gccggtcctt acaaaattga gtcagggcag atcctgaaat
    12781 ctgtcggaaa ccccatgtat acggaagtgt tcggaaatac cctgattgaa ctggctgaaa
    12841 aggatgaccg aattgtcacc attacacctg caatgccagg cggatcagga cttatgaaat
    12901 ttgccgaacg ctttccggat cgtatggtcg atgtaggaat cgctgaacag catgcggcta
    12961 cattcagtgc aggtcttgcc actgaagggc tgaaaccggt atttgccgtt tattccactt
    13021 tcatgcagcg ggcttatgac cagatcgtac atgatatttg ccgcccgaat ctgaacgtga
    13081 cgtttgccat tgaccgcgcc ggcttcgtcg gtcctgacgg ggaaacccat caaggggtat
    13141 ttgatatcgg atttatgcgg acactgccta atatggtgct gatgatgccc aaggatgaga
    13201 acgagcttcg gcatatgatg aagacggctc ttgagtatga tgacggaccc atcgcttacc
    13261 gttacgcccg aaccaacgga ctaggccttg aattggataa agagctgaga tccattccta
    13321 tcggaagctg ggaagtgatc cgtgaaggtc agtccgccgc cgtattggca gtagggccta
    13381 tggttcaagt agcagaggaa gctgctgaac agcttataaa agacgggatt cagcttagag
    13441 tgattaatgc acggttcatt aaacctatgg atgaagcgat gctgcttcag ttggcacagg
    13501 agaatcttcc tttgattact ttggaagaag gggctcagct gggaggattc ggcagcggtg
    13561 tattggaatt ttatgcggag caaggcatct atggaatgcg aatcaagacc atgggggtac
    13621 cggattattt tgtcgagcat ggctctatca gagagcagcg ctgcgaagtc ggactcacat
    13681 ctgataatat cattcttcaa gtaaagtctt ttttatcaag aaggcataat aaacgagccc
    13741 aataacccga tccttcaaac cccagaatag aatacaggag atggcaatgt cagataaaga
    13801 acgtattgat gtgcttctag tggagcaggg atattatgaa agcagggaaa aagccaaggc
    13861 cgccatcatg gcaggccttg tttttgtgaa tgaagaatct gtggacaaac cagggataaa
    13921 aataagccgg aaagaggata tacgggtgaa aggagctgtt cacccttatg tcagccgcgg
    13981 aggtttgaaa ctggaaaagg cgttaaaact gttttcgata gacgttacag gggctgtgat
    14041 gcttgatatc ggatcttcaa cgggaggatt taccgattgc gcactgcagc atggagcttc
    14101 ctatgtatat gctattgatg tgggatataa ccagcttgac tggtcattgc ggagtgatga
    14161 acgtgtaaat gtgatggaac gaaccaattt ccgctatttg acttcggctg atttacaggg
    14221 gccgaaaccg aattttgcta cgattgacgt ctccttcatc tctttaaaaa tcattctccc
    14281 tccccttaag caaatactgg ggaattttgg agaagtggtt gctttaatta aaccccaatt
    14341 tgaagccggg cgggaaaaag taggtaaatc cggggttgtg cgtgatccgg ctgtacatgt
    14401 gcaggttatt gaagaagtgg ttgagtttgc tgaaactatt ggttttttta tgaaaggact
    14461 aaccttttct cccataaccg gcggtgaagg aaatattgag tttctggtct atcttgcctg
    14521 caacccggaa gaccctttaa tcgtaaaaga aactatacag gcagctgcca agcaggtggt
    14581 tcaagaatcc cgggcactgc ggccgggaaa ctcatcttca tgatgagttt tcatacttct
    14641 taaggaaaaa agggtttttc ccctcgtcct agaaataata aggcgaggtg atccgcggtg
    14701 caaagtggtg atttatttgt tacattactg gttgtgaccg taattgtgtc ctggttaacc
    14761 ctgcgttttc gaaggtggct tgatgttcct gtaaagcaaa atatgccgat tcctcttgcc
    14821 aaggagcctg tacccgagga cgaagtagtg gagttgcttg aaggtgccgg ttttaatgtt
    14881 ctttcaggga aaatgaaggt tcccattctc atcactgtta acgacaccga ggatctgcaa
    14941 agccgacttt atctggatta ttttgctgaa aaaaaagata aactgtatgt agtgaaaaag
    15001 gccaggcaga gaaaaccaat ggagttgaca ggaacatctg ttcgtgatac gctactaatc
    15061 tatcagttgt tatatccgga aacggatgga gtattatatg tggatatgaa tcagctaaaa
    15121 ataaaaaaaa taacgtttca attagaggtg caggaatgaa aggacaacgc catgtcaaga
    15181 tcagagaaat tataacgaat aatgagattg aaacccagga tgaactggtg gagtccctcc
    15241 ggcagtccgg gtttaatgtg acgcaagcga ctgtctccag ggatattaaa gagctgcatt
    15301 tgattaaagt gcctcttcct gatggccggt acaaatattc gatgccggca gatcagcgtt
    15361 ttaatccagt gcagcggtta aagcgggcct tggcggacca tttcgttcaa attgattata
    15421 cggaaaatat gattgtcatg aagtgccttc ctggtacagc taataccata tgtgctctaa
    15481 ttgataacat ggagtggtct gaaataatgg gttccatttg cggagatgat acagttttgc
    15541 ttattatccg caataaagaa caaacctctc atgtagtcaa ccaaatatta tccttaatgt
    15601 aaggtaggag aatgtatgct tacagagctg tcaatccgta atttagcggt agtcgagtat
    15661 gttcatttgg tgttccgcca aggttttcat gtgcttacag gagaaaccgg agcaggaaaa
    15721 tcgatgatta tcgatgcgct cgggttaatt gtgggaggca gaagttcttc agagctggtc
    15781 cgccatgggt gtgacaggac agagattgaa gccgtatttg agctgcccgt ttctcacccc
    15841 gtatgggagg ttctggacaa gctggggatt atggcccgga cagacgaaca attaattatc
    15901 cgcagagatg taacggctca aggtaaaagc tccagccgca ttaacggcca gcttgtgaat
    15961 ctgacaatgc tccgtgaagt tggaaattgg ctggtgaacc ttcatggaca gcacgagcat
    16021 caatccttac ttaaagtaga agaacatatt catcagcttg atgtgtatgg tgaaagggaa
    16081 atagggaaag ctaaagccga ttaccaaaaa acatacaata tttatataaa gctacgccgg
    16141 gagctttccg aactggagga aaatagtaaa caatctctgc aaatgcttga tttatacagg
    16201 tttcagatta aggagattgc ggcggccggg ctgaaggaag gagaagacct ttggctgcag
    16261 gacgagaagc gcaaattgtc caatgccgaa aaactgtatc agcatgtcgc cgaatcttat
    16321 gatctcattt acgggggcaa ccaggggctg gatgcaatca gtggtgttgt tcataaactt
    16381 caggacatca ccagactgga tgccagacaa cttgagcctt tgctagagca aattcaatct
    16441 gcattttatc agcttgaaga tgccgcatat cagcttcggg attaccggga tcaagtggaa
    16501 ttcaatccgg acaggctgca agaaattgag gagagattag accttattgc taatttgcgc
    16561 cggaagtatg gagacgatgt atcagaaatt ctggaatata tggataaaat caagcgggaa
    16621 ctggatttaa tcgagaataa agatgaagtc atccagaaag tcaaggaaca attgttaaag
    16681 caggaagaag agcttattca taaagcggtc aggctttctt ccgtaagaaa acaagttgcc
    16741 aagcagctgg ctctggaaat agagtcagaa ctgaaagatc tccatatgga gagaacccag
    16801 ttcgagattc atatcgaatc cgtcccggac ccaaaaggaa tagaagtaaa tggggaactg
    16861 ctcaaattta cacgcgaagg aatagatgaa gttgaatttc ttatggcgcc caatcccggg
    16921 gaaccccttc gcggcttaag taaaattgct tcaggtgggg agttatcacg tattatgctc
    16981 gcacttaaag cgatatttgc ccgaatggag cagataccgg ttcttatttt tgacgaagtg
    17041 gataccgggg tgagcggcag ggcggctcag gctattgcgg agaaattatc ttacttatct
    17101 gaaaactgtc aggtgttttc catcactcat cttccgcaag tggcttgtat ggctgatgtt
    17161 catttttaca ttcataaaga aattcatgat gaccggactt ttaccaaagt ggaagatttg
    17221 aacgaaaatg gacgaattcg agagcttgca cgaatgctag gcggcgtaga agttacggat
    17281 acaaccttac atcatgcaca agaaatgatt gacatggcaa aagtcaaaaa aacaaggaat
    17341 gtctagtgga atcagacatc atttgcagtt ataaaacagc gggtcagcgg ttaccttata
    17401 ggtacgccaa tgacaagatc ggcgcggctt tcttcctgac agggagaagc cgctcttctc
    17461 ttgttaagcc acaagaagca aaaggagcgt ggttgatgtt gaaaaaagac caaataagaa
    17521 aatggattgg tctaatgctc gttttcttcg tgtgcctggt aagtttttcg accccgttcc
    17581 agaattttgc ctcattccct gaaacattaa gaattttcag cggtcaaggc aaacagctac
    17641 accttacgat gccggttcat gcccaactga aagtggctga cccgaacatt gttcaggtga
    17701 acggtcaggc gcagcactca tttcaagtta atttgaaaaa tcccatctca ttgcagtcgg
    17761 gtcattcagg tcaaacggaa atgcagttaa acttatttgg ccgaatcccc ctcaagactg
    17821 tcaaggtgca agtcgtaccg gatcttaaag tcattcccgg gggacaaact attggcgtca
    17881 agattaaatc ggcaggtatc cttgtagtgg ggcatcattt ggttacggcc gataaaggac
    17941 aaaaaatatc gcctggagag gaagctaaaa ttcatgtagg tgattatatc acccacatta
    18001 atggaaatcc ttccaacgat gttactaaaa ttgcccgaat cgtaaacgaa gccggcaaaa
    18061 gttctaagcc gctggatttg tctattacac ggggaaatca aaaactgaat atcaaactga
    18121 agcctgcata tgatgtatcg gaaaaatcct atcggcttgg cttgtatatc agagattctg
    18181 cggcgggagt tggaactctg actttttatg ctccaaaaca aggtgtatat ggtgcactgg
    18241 gacatgttat tacagatatg gacacccaga caccgataac tgtggggaat ggggaaattg
    18301 ttcattctaa tgtaacttcc atcgctaaaa gccaaaatgg agaacctggc gaaaaacatg
    18361 cccaaatttt taaagacagt aaagtcatag gaaatattga aaaaaatacg ccttttggta
    18421 tttttggaaa catgaagcag ccgccggacc atagtttttc cgataaagct attcccgttg
    18481 cttttgccga ggaagttaag gaaggacctg cgcaaattta tacggtatta aacggacaaa
    18541 aagtggagaa gtttgatatt gaagttgttc atgtatccaa gcagcaatac ccggctacta
    18601 aaggaatggt tatcaaaata acagatcccc ggctgctcga aaaaaccgga ggaattgtac
    18661 aaggcatgag cggcagtcct atcatccaga acgggaaaat gatcggtgct gtaacccatg
    18721 tctttgttaa cgaccctaca agcggatatg gctgtttcat tgaatggatg cttcaagact
    18781 cagggattat gcttaaaaac accgtgaaac caaaagaact aaaggccggt tagcctttag
    18841 ttcttttttg tcgaatcgtg gtggattttt agataaaata ttattatatg atatttgcac
    18901 aaaaaaataa agatattttt tattcgacag aaggatttta cagtgcgttg tcgaatacgt
    18961 atcattaagg aaaaatctta ctgattgttt ttcaggaagt taaaggaggc taaccacgtt
    19021 gcagaagatt caagtgttat tggcggatga taatcgagag tttacccaat tgctttccga
    19081 gtttattgga gagcaggaag acatggaagt gatggctgtt gcttacaacg gaaatgaagt
    19141 attgcgttta ttcgagcaga atgaaatacc ggatgtactg attttggata tcattatgcc
    19201 ccatctggac ggcctagggg tactggagaa acttcgtgag atgaatttga ctcctgctcc
    19261 caaaatcata atgctgacag cattcggtca ggagaacatc actcaaaaag cggttcagct
    19321 tggggcgtcc tattatatac tgaaaccatt tgatatggaa gtgttaacta accgaatccg
    19381 ccagctagtt ggaaaccagc cttccctcac ttcagccatt tcaaacaaag cgaatatagt
    19441 gcaaatgcct aagggtaaaa atttggatgc aaatatcacc acgatcatac atgaaatcgg
    19501 cgtacctgca catattaaag gatatcagta tctgcgtgaa gccattacaa tggtgtataa
    19561 caatattgaa atattagggg caattacaaa aaccctttat ccggctattg cagaaaaata
    19621 taaaaccaca ccaagccgcg tggagcgcgc tattcggcat gcaattgaag ttgcctggac
    19681 acgcggaaat atcgacagca tcagttatat ttttggatac acggtaaata tcagcaaatc
    19741 caaaccgaca aacagcgaat tcatcgcaat ggtagcggat aaattgcgga ttgagcataa
    19801 agtttcttga aagggttaga atctgtgagc cgataaaaca gaaataataa cccagtaaat
    19861 accatttgtt tattagtctt cccaaaagct gataaagaag tggtattttt tatgactaat
    19921 tttcacatca gcaattttct gctggtaaga aagtgaatca tcctggcaat agaagcgact
    19981 ttaaaaagga catcagaaac tgaaaatttc ttctgtattc attcatcatg tgatatacaa
    20041 tccaatggac ctgataatca aacctgttgt aactgctcga accagctttt tcacgcaaag
    20101 tattttcttc atagttctcc ctctcttcct tctaagctat catcggaggc tggcggaggg
    20161 taagacaaaa aaacctcata tacgtgagcg agaaggtccg taaaccatca tctacagtat
    20221 gatggccata agcttctttt ccctattaga actaagtatt tttaagatgt ttagataata
    20281 aagtaacaaa tgggtaacat gaggatttat tttaaaagct tctcataagt tctgcgaact
    20341 tgtgggaagc ttctttcttt ttgggcttcg tgacatgaag atatatgttt tttgttgttt
    20401 catcacttct atgtccgagt cgttgcatta tctgttctaa actaacccct gcttcagcta
    20461 gtagtgaggt atgagtatgt cgtaaagagt ggggagtaag cctagtgtta agttctgcaa
    20521 gtttgagcaa tcgcgtcata cggaaggaaa ttaatttttg ataaacagga aaacctgcgg
    20581 tttcttcgtc ttgttgagaa aatacaaagt tttcatcatg atatgttgtt ctaaaacgca
    20641 ttttgattct tttttgttta gcttgtagta gctctaattc atttaataca atgttatcca
    20701 cgtctatcaa tcgctttgat gattttgtct ttggggtcaa taagatgtaa tttttaagtt
    20761 taacatttgg gttgtaatat gtttttgtaa tactaattgt ttgttctgaa aaatcgatgt
    20821 cagaccattt taaggcacaa agttctccaa cccgcatacc ggtataggcc aaagtcaaaa
    20881 aaatagcata atcacgatct aatccttttt ct
//
