LOCUS       NZ_CP020557            20975 bp    DNA     circular CON 24-JUL-2024
DEFINITION  Paenibacillus larvae subsp. pulvifaciens strain SAG 10367
            chromosome, complete genome.
ACCESSION   NZ_CP020557
VERSION     NZ_CP020557.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus larvae subsp. pulvifaciens
  ORGANISM  Paenibacillus larvae subsp. pulvifaciens
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 4666454)
  AUTHORS   Dingman,D.W.
  TITLE     Paenibacillus larvae genome sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4666454)
  AUTHORS   Dingman,D.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2017) Entomology, CT Agric Expt Station, 123
            Huntington St, New Haven, CT 06504, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2016
            Assembly Method :: SMRT Pipe HGAP assembly v. February-2016
            Assembly Name                     :: sag10367-hgap-022916
            Genome Coverage                   :: 214.2x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002082155.1-RS_2024_07_24
            Annotation Date                   :: 07/24/2024 02:27:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,275
            CDSs (total)                      :: 5,166
            Genes (coding)                    :: 4,634
            CDSs (with protein)               :: 4,634
            Genes (RNA)                       :: 109
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 532
            CDSs (without protein)            :: 532
            Pseudo Genes (ambiguous residues) :: 0 of 532
            Pseudo Genes (frameshifted)       :: 400 of 532
            Pseudo Genes (incomplete)         :: 184 of 532
            Pseudo Genes (internal stop)      :: 26 of 532
            Pseudo Genes (multiple problems)  :: 72 of 532
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:07:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3158489
            Orig. end                         :: 3179464
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020557.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Dr. Adriana Alippi,
            CIDEFI-CIC, Facultad de Ciencias Agrarias y Forestales, Universidad
            Nacional de La Plata, 1900 La Plata, Argentina.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="15"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10975
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(284..293)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            complement(406..540)
                     /locus_tag="B7C51_RS16860"
                     /old_locus_tag="B7C51_16855"
     CDS             complement(406..540)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014052.4"
                     /locus_tag="B7C51_RS16860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16855"
                     /product="hypothetical protein"
                     /protein_id="WP_237088932.1"
                     /transl_table=11
                     /translation="MAILGIGSITGGLMSAVILFYNGYIIGKLIQFLFLNCLFRHFIQ"
     gene            complement(590..922)
                     /locus_tag="B7C51_RS16865"
                     /old_locus_tag="B7C51_16860"
     CDS             complement(590..922)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7C51_RS16865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B7C51_16860"
                     /product="hypothetical protein"
                     /protein_id="WP_083040932.1"
                     /transl_table=11
                     /translation="MIPIIALFIGFLIFPLIQIYLFPLITKFNFIHEYEIGTTEEETGI
                     VNKGQSFIRNFLVMPFIYCLISSPFFPFLQHSVEVVNVLSILYFAVISFICWIACHKTI
                     KKGIKR"
     gene            1131..1370
                     /locus_tag="B7C51_RS16870"
                     /old_locus_tag="B7C51_16865"
     CDS             1131..1370
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="B7C51_RS16870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16865"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_158530411.1"
                     /transl_table=11
                     /translation="MIMVGNLLESPMFQSLIPQYAKKLGIREDEVVQVYKDKVPLKRGC
                     HYEDVANAVVFYSSDQAFYMTGQSVNVTDGQVMH"
     gene            1392..1520
                     /locus_tag="B7C51_RS26055"
     CDS             1392..1520
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013116.4"
                     /locus_tag="B7C51_RS26055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transaldolase family protein"
                     /protein_id="WP_144029595.1"
                     /transl_table=11
                     /translation="MEILIDSANIQDIKRLCGFLPIQGVTTNPAIIVKEKKPFYHP"
     gene            complement(<1501..1650)
                     /locus_tag="B7C51_RS16875"
                     /old_locus_tag="B7C51_16870"
                     /pseudo=""
     CDS             complement(<1501..1650)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011246856.1"
                     /locus_tag="B7C51_RS16875"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16870"
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MANKSYKFRFYPTQEQEQLLAKTFGCVLIYNKMLAERKETYEKFK
                     DDKRV"
     misc_feature    complement(1685..1698)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.62"
                     /tool="antismash"
     gene            complement(1755..3566)
                     /locus_tag="B7C51_RS16880"
                     /old_locus_tag="B7C51_16875"
     CDS             complement(1755..3566)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012706.4"
                     /locus_tag="B7C51_RS16880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16875"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_036655250.1"
                     /transl_table=11
                     /translation="MQITYHYLRLRSSYEHVPDKVPHRVTLDQIAGVLFCTERNVKLLL
                     KKMAAHGWIEWKPGRGRGHASEITFLIAAEDVLAKEAADMAGRGDFTSAMELIQQFGEQ
                     YAPRKPFLEWLFSQFGIKSIEQEKSRLDTLRFPLFGLIHTLDPAYAVYGKECNILQHLF
                     NTLVRYNEKSRKLEPELAHHWESDGQQKIWTFYLRKGIYFHHGREMTAGDIKYTFDRLK
                     HPKVASYHSWLTEEIEDILITGPTTIQFQLKEPNCLFDHFLSYRAASIVPEEVVRGQGD
                     DFARHPVGTGPFQIELHNESACKLKVFENYYAERAHLDRIEIWFLPLNLPVSHPPSFWG
                     HLIIYEGKQAQSSLMEQNETGNWRSTKKILYDGCSLLVFNLGKQGPQQHPLFRKAMHSL
                     LDRDLMVKELAGNRVSAASGFSPELGCGQKFPPPDPIQICRLLEESGYQGEPLHLHTLS
                     HHEEDAEWIKRRCEFFGIQVELKFASIEDMLNPSSYIQADMVLYQIVLDSYLSMMEIFR
                     QSNGYVRSFMDAALLKQVDQILQHLIQEKDENARLQKMRELQSIVTQEHAILLLLHKSF
                     HVAFHPSVQGVSVNRYGWVDFNKLFLT"
     gene            3773..4015
                     /locus_tag="B7C51_RS16885"
                     /old_locus_tag="B7C51_16880"
     CDS             3773..4015
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7C51_RS16885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B7C51_16880"
                     /product="hypothetical protein"
                     /protein_id="WP_024095151.1"
                     /transl_table=11
                     /translation="MKTLHSSFRISRSEAKPTYRSSKQRLRSLEEEWLELQKFEERRTK
                     KSLQFMPETLKWFGIFGLSAMVIIAMMSIFVDMLR"
     gene            4134..4421
                     /locus_tag="B7C51_RS16890"
                     /old_locus_tag="B7C51_16885"
     CDS             4134..4421
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010272089.1"
                     /locus_tag="B7C51_RS16890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16885"
                     /product="hypothetical protein"
                     /protein_id="WP_024095150.1"
                     /transl_table=11
                     /translation="MKDLKGLKNVIYMSLAVGMLIYALPKLNLGEGFTLPTLFGVVWVC
                     FALFVVAAHLHELLGVDEERRQQMNRVQRMKKWQTEQTLQGRRKILQLRK"
     gene            4576..5913
                     /locus_tag="B7C51_RS16895"
                     /old_locus_tag="B7C51_16890"
     CDS             4576..5913
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009674567.1"
                     /locus_tag="B7C51_RS16895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16890"
                     /product="DRTGG domain-containing protein"
                     /protein_id="WP_042119292.1"
                     /transl_table=11
                     /translation="MDQVNTQSMTKHEQILRYIESLKLGTKISVRKIADQLEVSEGTAY
                     RAIKEAENLGLVSTKERVGTVRVGKKLRQNIDKLTFGEVVNIVDGEVLGGKNGLQKTLN
                     KFVIGAMELDAMVRYIEPGSLLIVGNRTGAHGLALKQGAGVLITGGFTTTDVIKELADE
                     MGLPIISSSYDSFTVASMINRAIYDRLIKKKIMLVEDIISSHTPVYSLKATSTPDDWKN
                     LLEQTGHSRFPVVDEWNRVIGVVTSKDMVGADPDQAVDKLMTRNPLTVYPSTSIASAAH
                     TMVWEAIELLPVVDSNRKMLAVISRNDVLKAMQYIQKQPQHGETFEDLICTGFEESRDE
                     SGGLLYKGVITPQMTNHLGTVSEGVLHTLITQAAFRAVQDVKRGDLVMDNISIYSIKPV
                     QIESEIIIKPQLLEVSRKFVKIDVSIHHQQMLVCKAMLTAQVIDRS"
     gene            complement(5897..6202)
                     /locus_tag="B7C51_RS16900"
                     /old_locus_tag="B7C51_16895"
     CDS             complement(5897..6202)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009674559.1"
                     /locus_tag="B7C51_RS16900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16895"
                     /product="YtpI family protein"
                     /protein_id="WP_023485471.1"
                     /transl_table=11
                     /translation="METVQMFLFIAIVVMLVISVWFSLKYRREKDPVTRGLNAARMNIA
                     MGIMLIIISITQLFFFTDSITRRIFGTVCLLLGLFNLFAGIRNNGHYSRLMSKNDR"
     gene            complement(6379..6531)
                     /locus_tag="B7C51_RS26060"
     CDS             complement(6379..6531)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7C51_RS26060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_024095147.1"
                     /transl_table=11
                     /translation="MKQVHFDQLFDDVWNETLDECIHAIEIPTRTIHYSLETVLEHLEA
                     GEQTL"
     gene            7032..9353
                     /locus_tag="B7C51_RS16910"
                     /old_locus_tag="B7C51_16905"
     CDS             7032..9353
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="B7C51_RS16910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16905"
                     /product="ATP-binding protein"
                     /protein_id="WP_083040933.1"
                     /transl_table=11
                     /translation="MKLMKYIRWLIPVFLVVQIWTVYITFTYPYLGIVVFQNEQGQWQV
                     NEFQKKSEGSNLVHKGDIVLSIDGQEPGDYFTVKKWKGIEQAGNIVVERDGGRIYSVDT
                     RNLPHPVAPGFIYLLAELLSIGFALLLMKKAGKSKSARLLALVFINIALLYMNVGASER
                     GDTLAKVLISNFMPILPFVFLKFLIEFFREKTGVHCKDGYLRFLYPTLTVIFVLRFSLF
                     LPNADYGTYQANFIAIAVFLLIGLILNFWLLISIYYRYAETHAYLAMILRTVMFSLFIS
                     FFPVVGLTFLPQVLFQQEIGYSFYNSWFVHFFPMSFAYLILSKQIYDIEIILRRLLYTT
                     IISIIPSVVLTAVITGLLYKDTHLEKILLTFITILLVMSVLIYSLEYLATKLEKIMFPR
                     KYYLQTALKKVAKDLEVITSFRELKEIVLVDIVNTLQVHGAAFVIQYPNDIEVIGEGMI
                     DPTEVENQFINRSWNEMGYTVAEINKHEEYNSYLVLTRKKTNTYMNREELQWLNLIITY
                     LSVSMENLYLIRKLHMRLHELASELPNQENGGDYVWFRKTMFELQEKERTRIASDLHDT
                     TMQDIFFVIRKLKSLQKQLTQTEDLRQIRDILNHLELINVNLRQCCFELNPYMLKNIGL
                     IGALRNLIDIESGLGSYEIQLITSGNLEEIEQMEDEKKRHIFRMIQELITNGRKHARAD
                     HLNIKLQADKGQLLVMYEDDGIGFQTESVASKVLGKSGMGLEQMKSRALHLNGLMDISS
                     EKGSGVRISIKIPVKEGVRV"
     gene            9350..9979
                     /locus_tag="B7C51_RS16915"
                     /old_locus_tag="B7C51_16910"
     CDS             9350..9979
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009674584.1"
                     /locus_tag="B7C51_RS16915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16910"
                     /product="response regulator transcription factor"
                     /protein_id="WP_083040934.1"
                     /transl_table=11
                     /translation="MNREWTVLIVDDHPAMAFGTKMILEARENIRVIGIASSGEEGLSL
                     VKSERPDIVFLDFHLPDMTGLEVASGMMKTHEELKIVIFTGIDFMPILNNLLSLGISGI
                     MSKDSSEEQITNMVYCLIEGQTAISLELFRQLQLGKGEDDGTALTDEEINIMNQIIKGA
                     TNEQIAEVIHMSKRSVDNYVRKIYDKFGVKSRAQAIEKFIQMKRPV"
     gene            10001..10975
                     /locus_tag="B7C51_RS16920"
                     /old_locus_tag="B7C51_16915"
     CDS             10001..10975
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="B7C51_RS16920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16915"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_083040935.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.4e-23, bitscore:
                     80.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPQVWKEINEITDRYFTEPDLNGLLKKSIADKAEETSIWSEMTL
                     YIHRMFGGNNPCLYRLGALTELLILGLDIMDDLQDKDNTGKVWMAMPEAAAMNVMNGML
                     MAALAELGNMKKEYAGQPFPCASEVSRMITTAINGQHIDIMGKVQTEEEYVAMVQQKSC
                     TLFRLSFYLGYSSAGPNLVSDLEAEQLQQFAVYAGMLGQIQNDIQDLTRYDIKNDLLYK
                     KRTLPILYLLAEDESDFPPIHQFYRSEITWEEFLTYKLECLEYINECGCVEYVSAIRHL
                     YATHANQLLDEIRVRNEWKERLRDVLLGAYNNEVMEEAEIKEG"
     gene            complement(11290..11832)
                     /locus_tag="B7C51_RS16930"
                     /old_locus_tag="B7C51_16925"
     CDS             complement(11290..11832)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7C51_RS16930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B7C51_16925"
                     /product="hypothetical protein"
                     /protein_id="WP_024095141.1"
                     /transl_table=11
                     /translation="MKLSKIKYFLVFASLVMFFSSVGAPIAGATNMDYDQRLKETEEIL
                     EFIGEHAVLTDEYDNIIGLDFDKIRERYGQDKGLDLLEKEVKEKTENNRSAWLDCMKSA
                     LLDYFGVNIFESLIGGGVLTYIKAKAWKEAAKLIIRYVPGVSVISLVATLVYYSGKCAI
                     WGMKEENGIEGKQHVYT"
     misc_feature    complement(11813..11826)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 22.42"
                     /tool="antismash"
     gene            12186..12359
                     /locus_tag="B7C51_RS16935"
                     /old_locus_tag="B7C51_16930"
     CDS             12186..12359
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7C51_RS16935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B7C51_16930"
                     /product="hypothetical protein"
                     /protein_id="WP_158530412.1"
                     /transl_table=11
                     /translation="MDNRITLRGELEKAIDETGCTLSQLEEKGGTQIGNLSACLRGKSL
                     RPITYIRILVYG"
     gene            complement(12954..13151)
                     /locus_tag="B7C51_RS29160"
     CDS             complement(12954..13151)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013648.4"
                     /locus_tag="B7C51_RS29160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_155116313.1"
                     /transl_table=11
                     /translation="MGEYVSLGSRRTPNLEKLMEAAPDLIIADPARHKDIQAKLNDIAP
                     TIYIKSSSSNYLEILDVYVC"
     gene            complement(13144..13311)
                     /locus_tag="B7C51_RS26070"
     CDS             complement(13144..13311)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7C51_RS26070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158530413.1"
                     /transl_table=11
                     /translation="MNIKPFFFRPAIHRRWLRKRSKSRAKGRNCRYLDKKIVAVTDDGD
                     KTSRSFPINR"
     regulatory      13842..13985
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            13987..14874
                     /locus_tag="B7C51_RS16945"
                     /old_locus_tag="B7C51_16940"
     CDS             13987..14874
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019450.4"
                     /locus_tag="B7C51_RS16945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16940"
                     /product="stalk domain-containing protein"
                     /protein_id="WP_083040937.1"
                     /transl_table=11
                     /translation="MATKWLKSLVLSGTLVTVGLIASNTTAHAAIPDGVKVQINNHLVN
                     FSDAMPYLNQGSIMVPLRAVAENLGYKLEFEMIQNGTQVRVKLIGDGHVFEFESGKQEA
                     KVDNRSITLDEAPVIKNDRVYVHIRSIAEHFGHIVQWDMNNNIGILGADGKYHAPAWYK
                     PAKRTTPSKDVTLSAKKSNESAGKQHTGKPADKQVSSAKKANESAGKQHTEKSADKQVK
                     PATSKDVTSFAKKSNESAGKQHTEKSADKKVEPATSKEIASTDKKSIVSKATGQVGVPY
                     LWGEVPQVGLIARV"
     gene            14832..15128
                     /locus_tag="B7C51_RS16950"
                     /old_locus_tag="B7C51_16945"
     CDS             14832..15128
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013073.4"
                     /locus_tag="B7C51_RS16950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16945"
                     /product="C40 family peptidase"
                     /protein_id="WP_077996946.1"
                     /transl_table=11
                     /translation="MGGSSPSGFDCSGLVTYIFKQQGINLPRTSSGMYGVGTSVSNPEQ
                     GDLVFFANGGKVFHVGVYVGGNRFISATDDGVKIDSLGNSYWNKYYIGAKKVM"
     gene            complement(15576..16166)
                     /locus_tag="B7C51_RS16955"
                     /old_locus_tag="B7C51_16950"
     CDS             complement(15576..16166)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7C51_RS16955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B7C51_16950"
                     /product="hypothetical protein"
                     /protein_id="WP_083040938.1"
                     /transl_table=11
                     /translation="MAVPFENPLFLPSLPAFTRNRFVFIRSNYWQQHFHGVYHQNFNFL
                     VVELRKLKSDNERLSLDLESLTKFKDKQTVIQRVTVHLKDSQTPPLNEDIRKELEKKVQ
                     NDMKVVVGQKVNSVNDSLELYEKLISDRTYYGVFEKDYVVRVKAIMLVKNELVFWIAAL
                     ERKPGAAGAPSDTEENKGKSQWFSPKKDDPFTM"
     gene            complement(16150..16482)
                     /locus_tag="B7C51_RS16960"
                     /old_locus_tag="B7C51_16955"
     CDS             complement(16150..16482)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018886079.1"
                     /locus_tag="B7C51_RS16960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16955"
                     /product="YtrH family sporulation protein"
                     /protein_id="WP_024095139.1"
                     /transl_table=11
                     /translation="MSDFITDMILDFFIAFGVVLGACMMGAVGSVLSLQPPTENMLLLA
                     ERIKIWAMVAAIGGTIDPIRVIESHVAGGDLSPAIKQIMIIVSAFMGAHMGATVIHWIA
                     KGGGSV"
     gene            16739..17053
                     /locus_tag="B7C51_RS29165"
     CDS             16739..17053
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7C51_RS29165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="transposase"
                     /protein_id="WP_051427932.1"
                     /transl_table=11
                     /translation="MADSFSRFFKKQNNKPQFKSKKNPVQSYTTQFTNNNIAILEGHIK
                     LPKLGPVKFAKSQEPNILNATICKNASGKFFVSILCEEEIYVLPKTDSAIGIDLGITET
                     "
     gene            17079..17297
                     /locus_tag="B7C51_RS29170"
                     /old_locus_tag="B7C51_16960"
     CDS             17079..17297
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013544.4"
                     /locus_tag="B7C51_RS29170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B7C51_16960"
                     /product="transposase"
                     /protein_id="WP_024095138.1"
                     /transl_table=11
                     /translation="MAAKKNGINLYEAKNYQKQKRKVARLHEKVMNQRNDFLNKLSTDM
                     IKNHDMICIEDLNTKGMLHNHKLAKSI"
     misc_feature    17409..17424
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.88"
                     /tool="antismash"
     misc_feature    complement(20080..20094)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.71"
                     /tool="antismash"
     misc_feature    complement(20180..20193)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     misc_feature    complement(20845..20858)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.23"
                     /tool="antismash"
ORIGIN
        1 ccattaagga atcctccaat gacaaacata ccagttacta gcaaatacaa aagagtaacc
       61 gccaaagctc ccttttcaga cccctccgca taatgaacaa ttccatgata aagaaggcgt
      121 aaaaaatatg tactaactga gaaagaaagc aattgcgtta taacaaaata gtggtctaaa
      181 tttaacgtta tgacgcaaaa tagagcaata ctattcacta gtaggataaa aacattatag
      241 acaaggatga caaggtacat tttacgaaaa acaaaatgct tattaaaaaa acacataaaa
      301 atcgaagtca agactgtact caaaaaattc aatataaaat ataacggaat ggccaaaaga
      361 aagataaaga caaaagtcgc tatctgcttt tcaatagata acgtctcatt ggataaaatg
      421 tctaaataaa caattcaaaa agagaaattg tattaatttc cctataatat aaccgttata
      481 aaagagaatt acagccgaca tcagcccgcc agttatagaa ccaattccca atatggccat
      541 actcacttga aggttgttaa gaaaaatatc aagaaaagat gattgattat catcttttaa
      601 ttcctttttt tatcgtttta tgacaagcaa tccaacaaat gaaagaaatt acggcaaagt
      661 ataggatgga taacacattc accacttcaa ctgaatgctg cagaaacgga aaaaaaggag
      721 atgagattaa gcagtaaatg aacggcatga caaggaaatt tcgtataaac gattgtccct
      781 tattcacaat gcctgtttct tcttctgtcg tcccgatttc atactcatgg ataaagttga
      841 atttcgtaat aagcggaaac aaatagatct gaatcaacgg aaatattaaa aaaccaataa
      901 acagagcgat aataggaatc atgataagta atcctaatac acctgccacg agcagcgtcg
      961 ttgcagcggg tgaacctatc aacttctgag cttgaagaaa agcagaccct tctgaaaaca
     1021 aaaatacctg aatggagtga aggtgatcgg aataaagaga aaccaactgc tcagataatt
     1081 gaatccaagg cgcattatca acattctggc tgattatgga atccgtaaat atgattatgg
     1141 taggaaacct gctggagtct cctatgttcc aaagtctgat tccacaatat gcgaagaaac
     1201 tgggcatccg ggaagatgag gttgttcagg tatacaaaga taaagttcct ctcaaaagag
     1261 gatgtcacta tgaagatgta gccaatgcgg ttgttttcta ttcctcagac caggcttttt
     1321 atatgacagg gcaatctgtt aacgtgacag acggacaagt catgcattaa taaacatgga
     1381 gcggataaga tatggagata ttaatagatt ctgctaatat tcaagacatc aagagattgt
     1441 gcgggtttct tcccattcag ggggttacaa caaacccggc cattattgtg aaagaaaaga
     1501 aaccctttta tcatccttga atttctcata cgtttccttt cgttcagcta gcattttgtt
     1561 gtagataaga acgcagccga aagttttcgc caggagttgt tcttgttctt gtgttgggta
     1621 aaaacggaac ttatatgatt tgtttgccat aatgaatcac ctcatttcta ttccattata
     1681 taacaaaacg tatgttttga taaaagaaaa caccatttat ctcccaccta tagaggaagg
     1741 agacttctgg tgtattacgt taaaaaaagc ttgttaaaat cgacccaccc gtatcggttt
     1801 acagaaacgc cctgcacgga tggatgaaag gctacatgaa acgacttatg aagaagcagc
     1861 agaattgcat gctcctgtgt aacgatgctc tgcaattctc gcatcttttg caggcgggca
     1921 ttctcatcct tttcctgaat cagatgctgc aggatttgat ccacttgttt gagcagcgca
     1981 gcgtccatga aagagcggac atatccattg gactgccgga agatttccat catggaaagg
     2041 taggaatcca gcacaatctg atacaaaacc atatcggcct gtatatagga ggagggattc
     2101 agcatatcct caattgaagc aaactttagt tcaacctgaa tcccaaaaaa ctcgcaccgc
     2161 cgtttaatcc attcggcatc ctcctcgtgg tgagataacg tatgaaggtg caagggctct
     2221 ccctgatagc cggattcctc caggaggcgg cagatttgta tcgggtccgg cggcgggaat
     2281 ttctgcccgc agccaagttc cggactgaag cctgaagcgg cacttactct gttgccggca
     2341 agctctttca ccataaggtc acggtcaaga agagaatgca tcgcttttcg aaaaagggga
     2401 tgctgctggg gcccctgttt gcccagattg aacacaagaa gactgcatcc gtcgtacagt
     2461 atctttttgg tactgcgcca attaccggtc tcgttttgct ccatcagact gctttgagct
     2521 tgctttcctt cataaataat cagatgcccc caaaatgagg gaggatgaga aaccggaaga
     2581 ttgagaggaa gaaaccagat ttcaattcga tccaggtggg ccctctccgc ataataattt
     2641 tcaaaaacct tgagtttgca agcagactca ttgtgcaatt ctatctgaaa aggtcccgtc
     2701 cctacagggt ggcgggcaaa gtcgtctcct tgtccccgga ccacttcctc cggcacaatg
     2761 gaggcagccc ggtaagacag aaaatggtcg aatagacaat tgggctcttt cagctgaaat
     2821 tggatagtag taggtcctgt aatcaaaata tcctctatct cttctgtcaa ccagctatgg
     2881 taagatgcga cttttggatg tttaagacgg tcaaaagtat atttgatatc gcccgctgtc
     2941 atctcacggc catgatgaaa gtagattcct ttgcgcaaat agaatgtcca aatcttctgt
     3001 tgcccatcgg attcccaatg atgagccagc tctggttcaa gctttctgct tttttcattg
     3061 taccggacca acgtattgaa taaatgctgc aaaatattac attcttttcc gtaaacggca
     3121 taagcagggt ccagggtatg aataagccca aataagggaa aacgaagcgt atccagtcgg
     3181 cttttctcct gttcgatgct cttgatgcca aattggctga acagccattc aagaaacggt
     3241 ttccttggtg catattgttc gccgaattgc tggatcagct ccatggcgga cgtaaagtcc
     3301 cctctgcctg ccatatcggc cgcttccttg gcaagtacat cttcagcggc aataagaaac
     3361 gtaatttctg aggcatgccc cctgccccgt cccggtttcc actcaatcca tccgtgagcc
     3421 gccatttttt tcagcagcag cttcacgttc cgttccgtgc agaacaggac tcctgctatc
     3481 tgatcaagag tgactcggtg tgggacttta tcgggcacat gttcatacga actccgcaaa
     3541 cgcaaataat gataagtaat ctgcatatga atgtaccttt ctctaaaagg ggaaatatgt
     3601 aaattctatt ataatcgttt tttttatcta tggtaagagt atttagacaa ataatggaag
     3661 attatagaaa attggaaaag gataatttgc aatctccaag aagaatccct ataatgtatt
     3721 taggaaatat tttcttttta agccaataga agttaatcga aggagcgtta ttatgaaaac
     3781 cttgcattct tcttttcgta tctcaaggtc cgaagcgaaa ccgacttatc ggagcagtaa
     3841 gcagcgtctg aggtctttgg aagaggaatg gttggagctt cagaaattcg aagagcgaag
     3901 aacgaaaaaa tctttgcaat ttatgcccga gactctgaaa tggttcggaa tattcggatt
     3961 aagcgctatg gtgatcattg ccatgatgag tatttttgtc gatatgctca ggtaagtctg
     4021 atcagactga acatttcctc tccattatta tgacagtctc tcaatgacaa tcatcatatt
     4081 tgtcctagtt tgttcataga ataaaaacaa atatgagttg tttaagaggg gacgtgaaag
     4141 acttgaaggg gctaaaaaat gtaatttaca tgagtctggc tgtcgggatg ctgatctacg
     4201 cattgccgaa actcaatctt ggagagggtt ttacactgcc gacccttttc ggagtggtgt
     4261 gggtatgttt cgccctgttt gtggtggcgg cacatcttca tgaactgctt ggggtggatg
     4321 aggagagaag acaacagatg aaccgtgtgc agcgaatgaa gaagtggcag acggaacaaa
     4381 cgctacaggg gagacgcaaa attcttcaac ttcgcaaata aggaatggga atatgcatca
     4441 atcattcgga acgttttgtt gaaacggtcg ccagtctatt taaggatggc ggccgtttcc
     4501 gtttgtttgt tatttttcgt ttctggcaat ataatttaat aaagtgttac agtttgggaa
     4561 attggggtgt aacagatgga tcaagtcaat acgcaatcga tgactaaaca tgaacagatt
     4621 ttacgatata ttgaaagctt gaagctaggc accaaaattt ctgttcgcaa aattgccgat
     4681 caattggaag ttagcgaagg tactgcttat cgggcgatca aagaggcgga gaacctgggc
     4741 cttgtcagta cgaaagagcg tgtcggaacc gtccgtgtag gaaagaaact gcgccaaaat
     4801 atagacaagc tgaccttcgg tgaagttgtc aatatcgtgg atggggaagt gctcggaggc
     4861 aaaaacggct tgcaaaaaac gctgaacaaa ttcgttattg gggcgatgga gcttgatgcc
     4921 atggtccggt atattgaacc gggcagccta ctgattgtgg gaaaccggac aggcgctcat
     4981 ggactggccc tgaaacaggg ggcgggcgtc cttataacag gagggtttac aaccacagac
     5041 gtgattaagg aactggccga cgaaatgggc cttccgatca tttccagcag ttatgattct
     5101 ttcacggtag cttccatgat taatagggct atctatgacc gtcttatcaa aaagaaaatc
     5161 atgctggtag aggatattat ttcatctcat actcccgtct actcccttaa agcgacaagc
     5221 acgccggatg attggaagaa cttgctggaa cagaccggac acagccgttt tcctgtagtg
     5281 gatgagtgga accgggtaat tggagtagtc acatccaagg atatggtggg ggctgatccg
     5341 gatcaagcgg ttgataagct gatgactcgt aacccgctaa ccgtataccc gagcacttcc
     5401 atagcttcgg cggctcatac gatggtttgg gaagctattg aactgctccc ggtagtggat
     5461 tccaacagaa agatgcttgc agtgatcagc cgtaatgacg tactcaaggc aatgcagtat
     5521 attcaaaagc agcctcagca cggcgaaaca ttcgaagatc tgatctgtac agggtttgag
     5581 gaaagcaggg atgaaagcgg cgggcttttg tacaaaggag tgataacccc gcaaatgacg
     5641 aatcatcttg gaacggtatc ggaaggcgtt cttcatacgc tgatcacgca agccgccttc
     5701 cgggccgttc aggatgtgaa acgcggggac ttggtcatgg ataatatttc aatctactcc
     5761 atcaagcctg tccagattga gagtgaaatt atcattaagc cccagctgct tgaagttagc
     5821 cgtaaatttg taaagattga cgtatccatt catcatcagc agatgctggt atgtaaggct
     5881 atgctgacgg ctcaggttat cgatcgttct tagacattaa gcgggagtaa tgaccgttat
     5941 tccggatgcc tgcaaacagg ttaaacagac cgagcagcag gcagaccgtt ccaaaaatgc
     6001 ggcgggtaat tgagtctgta aagaaaaaca actgggtaat agaaataata atgagcatga
     6061 tgcccatggc gatattcatg cgtgccgcat ttaggccccg tgttaccggg tccttttccc
     6121 tgcggtattt caggctgaac cagacagaaa tgaccagcat caccacaata gcgatgaaca
     6181 gaaacatttg aacagtttcc atgtaaatgt cctccttgcg tacaaaagat agggtccaag
     6241 atggttttga taatgtaact gtacaaattt ttacatccat ttgcaattgg cagtcaaaag
     6301 atgtgtacac aaaaaaagaa acctcctgct tctgttacag aggttttctg tataaaggta
     6361 tttttgtttt tgataagact aaagagtctg ctctccggct tccagatgct caagaacggt
     6421 ctctagtgaa taatgaatag ttcgcgttgg aatttcaatt gcatggatgc attcgtctaa
     6481 tgtttcattc cacacatcgt caaacagctg atcaaaatga acttgtttca taattgcact
     6541 cccgtttatc aagatggtta attctgtata agaatgtcta cttttatatt atcttttggg
     6601 gagccattat tcagcgtaaa tgtatttcgc ttccatgcac attttattac atatatgcgc
     6661 aacagggtgt agtcgtacaa aaaaagattg catattagca caagccaata tgcaatctct
     6721 tttcacattc tgataagatg aagataagga ttaataccaa ctgcctggtg gacgaactcc
     6781 ttttctttca tttatcccgg agttttgtgc gaaagctttg gtaatggatt gctgttccat
     6841 cgatgtaaga atcaaagact cttgttttaa gccggattta agcgatttga ctgcactttt
     6901 aagatcttgg gaccaaagaa tggtagcttg catactttac acctcacctt agaaatttgg
     6961 ttcctataca taggtacctg tacctatgat ataccaaata atacctagtt tcaaagggag
     7021 atttgaaatt aatgaaatta atgaaatata taagatggtt aatccctgtg tttcttgttg
     7081 tgcaaatttg gacagtttat atcacattta cttaccctta cctggggatt gtggtattcc
     7141 aaaatgaaca ggggcagtgg caagttaacg agttccaaaa gaaaagcgaa ggatcaaatc
     7201 ttgtacataa aggcgatatt gtgttaagta ttgacggaca agagccgggc gattatttta
     7261 ccgtgaagaa atggaaggga attgaacagg ccggtaatat cgttgttgaa agggatggag
     7321 gaagaattta ctctgtagat acccgtaatc ttccccatcc ggtagctccg ggttttatct
     7381 atttgttagc ggaattactt tccatcggat ttgctcttct gctgatgaaa aaagcgggaa
     7441 aatcgaagtc cgcaagactg ctggcccttg tatttatcaa tattgctctg ctttatatga
     7501 acgtgggggc ttcggaacgg ggagatactc tcgcgaaagt attaatttct aatttcatgc
     7561 ctatactccc ttttgttttt ctaaagtttc ttatcgaatt ttttcgagaa aaaacaggcg
     7621 ttcattgcaa ggacggttat ttgcgttttt tgtatccgac cttgacggtg attttcgtac
     7681 tgcgtttttc tttgttttta cccaatgctg attatggtac ttatcaagcc aattttatcg
     7741 ctatagcggt ctttctcttg attggactga tcctgaattt ctggctcctg ataagtattt
     7801 attatagata tgccgagaca cacgcttatc ttgccatgat tttaagaacg gtgatgtttt
     7861 ccctgtttat ttcgtttttc ccggttgtag ggttaacttt tttgcctcag gtgctttttc
     7921 agcaagagat cggatactca ttttataata gctggtttgt ccactttttt ccgatgtcgt
     7981 ttgcttatct gattctgtcc aagcagattt acgatattga gattatatta cggagattgc
     8041 tttataccac gataatctcg attattccca gtgttgttct aacagctgtg atcacaggat
     8101 tactgtacaa agacactcat ctggaaaaaa tattgctgac ctttattacg atcctgctgg
     8161 tcatgtccgt actgatttat tcattagaat atctggcgac gaaacttgag aaaattatgt
     8221 ttccccgcaa gtattatctt cagactgcac tgaaaaaagt cgccaaggat ctggaagtca
     8281 ttacgagctt tcgggaactg aaagaaatcg tgcttgtgga tattgtaaat actctgcagg
     8341 ttcatggggc tgcctttgtc atacaatacc cgaatgatat agaagtgatc ggtgaaggaa
     8401 tgattgatcc aacagaggta gagaatcagt ttattaacag aagctggaat gaaatggggt
     8461 atacggtagc tgaaataaat aaacatgaag agtataacag ttaccttgta cttacgagga
     8521 aaaagaccaa tacttatatg aaccgggaag aactgcaatg gctcaatctg attatcactt
     8581 atttatccgt cagtatggaa aacctgtatc tcatccgcaa acttcatatg cggttgcatg
     8641 aactggcttc ggaactgcct aaccaggaga acgggggcga ctatgtctgg ttcagaaaga
     8701 cgatgttcga gcttcaggag aaggaacgca cacggattgc ttccgacctt cacgacacga
     8761 cgatgcagga tatcttcttt gtcatccgca agctgaaatc ccttcaaaag cagctgacac
     8821 aaacggagga cctcaggcaa atccgggata ttttgaatca tcttgaactg atcaacgtca
     8881 acctgcggca gtgctgtttt gaactgaatc cttatatgct taaaaatatc gggcttatcg
     8941 gtgctctgcg caatctgatt gatatagaat cagggcttgg cagctatgag attcaattga
     9001 ttacatccgg caacctggag gagatagaac agatggagga tgagaagaaa cggcacatat
     9061 tccgcatgat ccaggaactg attacgaacg ggaggaaaca tgcccgggcc gatcatctga
     9121 atatcaagtt gcaagcagac aaggggcaac tgctggttat gtatgaggac gacggaatag
     9181 gttttcaaac cgaatctgtt gcatccaaag tgctcgggaa gtcaggtatg ggactggaac
     9241 agatgaagag cagggccctt catttgaacg gcctaatgga tatttcctcg gaaaaaggca
     9301 gcggggtacg aatatctatt aaaatcccag tgaaagaagg tgtgagagta tgaaccgaga
     9361 atggacggta cttatcgtgg atgatcatcc ggcaatggca ttcggtacga aaatgattct
     9421 ggaggcaaga gaaaatatcc gggtcatagg gattgcatct tccggagaag aggggctcag
     9481 ccttgtaaaa agtgagcgcc cggacatagt ctttctggat ttccatcttc cggatatgac
     9541 aggacttgaa gtggcatccg gtatgatgaa aacccatgaa gaactgaaga tcgtgatttt
     9601 cacgggtatt gatttcatgc cgattttgaa caacctgttg agcctgggca tcagcgggat
     9661 tatgtccaaa gattcaagcg aggaacaaat tacgaacatg gtgtattgcc tgattgaagg
     9721 gcaaaccgct atttccctgg agcttttccg ccagcttcag ctgggtaaag gggaagatga
     9781 cggcaccgcc ttaacggatg aagagatcaa cattatgaat cagattatca aaggggcgac
     9841 caacgagcag atcgctgagg taattcatat gagcaaacgc tctgtagata attatgtacg
     9901 caaaatttat gataaattcg gcgtaaaatc acgggcccag gccatcgaga aatttatcca
     9961 aatgaaacgc ccggtgtgac gccaacggga ggaaccagaa atgaatccac aagtttggaa
    10021 agaaataaac gaaatcactg accggtattt tacggaaccg gatttaaacg ggctgcttaa
    10081 aaagagtata gcggacaaag ccgaggaaac atccatctgg tcagagatga ctctttatat
    10141 ccatagaatg tttggcggaa ataacccttg tctatacaga ctgggggcgt tgacggaact
    10201 gcttattctt ggactggata ttatggatga tcttcaggat aaagacaata ccggcaaggt
    10261 ctggatggcg atgccggaag cagcagccat gaacgtaatg aatggtatgc ttatggcagc
    10321 tttagccgag ctggggaata tgaaaaagga gtatgcgggc cagccgtttc cttgtgcttc
    10381 tgaagtaagc aggatgatta cgacagccat taacgggcag cacatcgata ttatgggcaa
    10441 ggttcagacg gaagaggaat atgtagctat ggtacagcag aaatcctgca cattgttcag
    10501 gctctctttt tatctggggt attcctctgc aggaccgaat cttgtctccg atttggaggc
    10561 ggaacagctt cagcaatttg ctgtctacgc aggtatgctt ggccagattc agaatgatat
    10621 ccaggatctg acccggtatg atattaagaa cgatttgctg tacaaaaaaa gaacactccc
    10681 cattttgtat cttcttgcag aggatgaatc ggattttcct cccattcatc agttttaccg
    10741 ttcggagata acctgggagg aattccttac ttataagctg gaatgccttg aatacataaa
    10801 cgagtgcgga tgcgtggaat atgtctctgc cattcggcat ttgtatgcca cacatgcgaa
    10861 ccaactgctg gatgaaatcc gtgtccggaa tgaatggaag gaacggcttc gggatgtttt
    10921 gcttggtgcc tataacaatg aggtcatgga agaggctgag ataaaagagg gataataggt
    10981 gaaaaaagtg gtgccggatt aggtaatgtg gagttggtaa atcaataatg atgatgaaaa
    11041 aagacattgg atgtatttct ttccaatgtc ttttttttgt gcaatgctga agcttaagtt
    11101 gatgttcttt tatccactta tttactcttt ttatcaaatt taaatataga gaaataaatg
    11161 agtgaacaaa cataaaaaat agccgtaatt acaaggactt caatccaatt ggtttgtttg
    11221 ttaaaaataa gatggtataa gacgaaaacc aatgcgaaca ccaatgaaag gataatataa
    11281 agtaaccagt taggtataga cgtgttgttt tccttcaatt ccattttcct ccttcattcc
    11341 ccatattgcg cacttaccgc tatagtatac caaagttgcc actaagctta ttacacttac
    11401 tccagggaca tatcttatta taagttttgc tgcttctttc catgcctttg ctttaatata
    11461 agtcaataca cctccaccaa tcaaagattc aaatatattt actccaaaat aatccaataa
    11521 agcagatttc atacaatcta gccaagcgct acgattattt tcggtttttt ccttcacttc
    11581 tttttctaat aaatctagtc ctttatcttg accatacctt tctctgattt tatcaaaatc
    11641 cagaccaatt atgttatcat attcatctgt taacactgcg tgttcaccaa taaattctag
    11701 tatttcttct gtttctttta gtcgttggtc ataatccatg tttgttgctc cagctatagg
    11761 ggcacccact gaagaaaaaa acataactaa actcgcgaac accaaaaaat acttgatctt
    11821 gctcaacttc attttaatta cctccttggt atatttttga ccccttatat aggaatcaga
    11881 ttacattttc tacaaaggaa gtaaaacatc ctccatctaa atacatattt accataataa
    11941 aacatttctc tttcagtata tgctcttagg cctccataaa ttcacataat tttaaaccgg
    12001 tcctcctatc tccagacatg cctactaggt ctttttaaag gtcataataa aaggaaatca
    12061 tgccgtctga tcgtcgggac gatatttaac atcagtcatg attgatgtac aaaattgcag
    12121 aaaaattcaa atgtagtatt atggaattat atggtactct gggcaaagag agaaggaaga
    12181 aaaaaatgga caatagaatt acgttgcgtg gcgaacttga aaaagccata gatgaaaccg
    12241 gatgtacact atcccaactg gaagaaaagg gcggtaccca aattggaaat cttagtgcct
    12301 gccttcgcgg caaatcgctc cggcctatca catatattcg aattttggtc tatggttgag
    12361 gagtttactg aagaactgcg gatactatcg aatattgtat atctagagga gttaagaaaa
    12421 cttaataaca atagatcgga accaccagta gaaaccgaac gacatcttgt tgtttattac
    12481 ggtaaatcat atttaataaa aggcgcggcc ttatttaaac aaggtcgttg aggaaaccaa
    12541 agcatgtatt gaaagatatc aagaccccag ctggtttaaa catttggatg atttaggaaa
    12601 gatggaagtc aaaaaatata gccaattgca aaagcaaata ggtatagcgt agaattgcta
    12661 ttagggaata ctgatgtact tgataagttc ttgaatttcc tcacagatta tccccaacat
    12721 acttcaggag cacttttagt tattttagag gtagcgaata catacggata ttaaatatag
    12781 accacatttt ggaacgattc gctaattcct actagaacat cccaacagaa tgtggtgttt
    12841 gctcagaaac aattgaggtt ttattagcag gcgctttttt tgccaatgtc ttgatttgtt
    12901 ccagatgagc ctgtacattt tttcggtagt ctctttttgt tgaagcgctg cccctagcat
    12961 acatagacat ctaatatttc tagatagtta gaagacgagc tttttatata aatggtcggt
    13021 gcaatatcgt tgagctttgc ttggatatct ttgtgtcgag ctgggtctgc gataatgaga
    13081 tctggtgctg cttccatcaa tttctccaga tttggcgtgc gccttgagcc gagagaaacg
    13141 tactcaccga tttatcggaa agctgcggga tgttttatct ccgtcgtctg tgaccgctac
    13201 tatcttttta tcaagatacc ggcagtttct gcctttggct cttgatttac ttcgtttccg
    13261 caaccagcgg cgatgaatag caggacgaaa aaaaaacggt ttaatgttca cgttttcccc
    13321 ctccctcttt ttttccgtca ctaccgaagt cagaattgta tagattgtcc ccttaaatca
    13381 gcctgtacaa aggcaaaagt ggaacgggga aatccgggtg aagcctcctc ccatatgtct
    13441 ccgccctgct gatgaaacca attattttgg acgtgaagcc atgttcctga acataagatg
    13501 tctccaatcc ccttttggct ttgtaaaaag gtcttgtttt taatcgtaat atttactatt
    13561 ataaagacag ctttacgaat ggtcaatagt acaaggacac ttttgggaag ggagtgatga
    13621 aaggggaggc tggatggacc gggaccgggt ttccggtttt gatctgaaag gatttccaga
    13681 tgaacgctct caaatgtgga tagagggtat tagctcagga taaatttgcc aacaagctat
    13741 attaattttt tatgatggaa aaaatttttt aaatggccac gaaagttgca agactccaat
    13801 taattatgct aaccttgcca aagacgagga agcttgtttt gttttaataa aagccgaatc
    13861 ttgctcttct acatgaggaa caggtacggg ggacgatatg ctgtggggtg aatttgcaat
    13921 attgtgcatt agggaatacc tcttcccgaa ccactaacct cggaggctac gtacaggagg
    13981 gaatttatgg ctacaaaatg gttgaaaagt ttggttcttt cagggacttt agtaacggta
    14041 gggttaatag catcaaatac tactgcacac gcagctattc cggacggtgt taaagttcag
    14101 atcaataacc acttagttaa tttttcggat gctatgcctt atttgaacca aggatcgata
    14161 atggtcccgc tgcgagcggt agctgagaat ttaggctaca aattggagtt tgaaatgatt
    14221 caaaatggta ctcaagtcag agtcaaactc ataggagatg gtcatgtatt tgagtttgag
    14281 tccggtaagc aggaggcaaa agtagataac agaagtataa ccctagatga agcacctgtt
    14341 attaaaaatg accgtgtcta tgtacatatc cgttcaattg cagagcattt tggacatatt
    14401 gtccaatggg atatgaacaa taatatcggc attctgggtg cagatggaaa ataccatgct
    14461 cctgcatggt ataagcctgc aaaacgaact acaccaagca aagatgtaac cttgtctgct
    14521 aagaagtcaa acgaatctgc aggaaaacag cataccggga aacctgctga taaacaagtc
    14581 tcatctgcta agaaagcaaa cgaatctgcg ggaaaacagc ataccgagaa atctgctgat
    14641 aaacaagtaa aaccagctac aagtaaagat gtaacctcgt ttgctaagaa gtcaaacgaa
    14701 tctgcaggaa aacaacatac cgaaaaatct gctgataaaa aggtagaacc agctacaagc
    14761 aaagaaatag cctcaactga taaaaaatcc atcgtatcta aggcaacagg gcaggttggg
    14821 gtaccatact tatgggggga agttccccaa gtgggtttga ttgctcgggt ttagtaactt
    14881 atatctttaa gcaacaaggt ataaatcttc cgaggacttc ttcaggcatg tatggtgtgg
    14941 gaacatcggt atcgaatccc gaacaagggg atcttgtatt tttcgctaat ggcggtaaag
    15001 tgtttcatgt aggcgtttat gttggtggca accggtttat ttctgcaacc gacgatggag
    15061 ttaaaattga tagtttagga aattcttatt ggaacaaata ttatataggc gctaaaaaag
    15121 tgatgtaaga ttatattcgt attggaacag ttaagaccaa gtcacttttc gaattttgtc
    15181 cgaaaagtga ctttttatat aatttcataa cttagatttt ccatccgaac aggtacaaga
    15241 tatagataaa tctgaaccgt atttgtatct tctctaccta ctgttgattc caatataaaa
    15301 taagttgccc tgcaattgat tacaacctgt taacaagaaa catggaaatt cttcacataa
    15361 tacaaaaagg gacgagtatt acgccttgaa gcaaagggga aggggaacag gaaagctatc
    15421 gaggcgcttg caaagcttgt agagaacaaa tttggcgagg attgataagg gtgtttccgc
    15481 tgcccaaaag gggccagccc aaaaaagaga agagaccttc atttatctta cagttaggat
    15541 tttggaggtc tcttctttgt tatatatacg ggactttaca tagtaaaagg gtcatctttt
    15601 tttggagaaa accattggct tttcccttta ttttcctctg tatctgaagg ggctccggca
    15661 gcgccgggtt ttcgctctaa ggccgcgatc cagaatacaa gctcattttt tacaagcata
    15721 atggccttca cccttacgac ataatctttt tcaaagacgc cgtaataagt ccggtcggaa
    15781 atgagtttct catatagctc cagagaatca ttcacactat tgaccttttg cccgacaacc
    15841 accttcatat cgttttggac tttcttttca agttctttgc ggatatcctc gttcagggga
    15901 ggtgtctggc tatctttcaa atgtacggtg acccgctgga tgacagtctg cttgtcctta
    15961 aatttcgtta aagattccag atcaagagag agccgttcat tatcggattt cagtttccgg
    16021 agttctacaa caaggaagtt aaagttttga tgataaaccc catgaaaatg ctgctgccaa
    16081 taattactcc ggataaaaac aaaccgattc cgggtaaaag ccgggaggct cggtaaaaag
    16141 aggggatttt caaacggaac cgccaccctt ggcaatccag tggatcacgg tagctcccat
    16201 atgagctccc ataaatgcac tgacgatgat cataatctgc ttaatggctg gcgataaatc
    16261 ccctcccgcc acatgacttt caataaccct gatcggatca atagttcccc ctatggcggc
    16321 taccatggcc cagattttta tccgttcggc aagcagcagc atattctccg taggaggctg
    16381 gaggcttaat acggatccga ctgcacccat catacaagca cccagcacaa caccgaatgc
    16441 aataaaaaaa tccaaaatca tatctgtgat aaagtcgctc attcggagtg ctccttcctt
    16501 ttgcaaaacc cttgtctcta cattgtatgg ggacctgtcc gcattatgac tgaaattgat
    16561 gaaaaagctt gcgcaaactc gtgacttcag tcgtgagtaa gcaagcttcg gttgaggcat
    16621 aggctttagc tatgtcaatc gaccgagata tattgaacta aataaactgc ctaacactta
    16681 tataatcgga tttcaacaga tacatatgtt aaaattattt agaggtgttt ttctatgttt
    16741 ggcggattct ttttctcgat tcttcaaaaa gcaaaacaat aaacctcaat ttaaaagcaa
    16801 aaagaatcct gtacaaagct atacaaccca atttacaaac aataatattg ctatattaga
    16861 aggacatatc aaacttccta aactaggacc ggttaagttt gctaaaagtc aagagcccaa
    16921 tatccttaat gctacaattt gcaagaacgc cagtggaaaa ttcttcgtat ctattctttg
    16981 tgaagaagaa atatacgtgc ttccaaaaac ggattctgcc attggtattg acttaggcat
    17041 cacagaaacg tgaacaacgt aagctgtcca gacgtgcgtt ggctgctaag aaaaacggta
    17101 tcaacctata tgaagcgaaa aactatcaaa aacaaaagcg taaagtcgct cgtttgcacg
    17161 aaaaagtaat gaatcaacgc aatgactttc tgaataagtt aagtacagac atgatcaaaa
    17221 accacgatat gatctgtatt gaggacttaa acacaaaagg tatgttgcat aatcataaac
    17281 tagcgaaaag tatttaagag aaacctctgt tggtaaagaa atacgctaac aagtatgctc
    17341 tcttcccaag aacctcgtga ttttagtcat gagaggttca agaagaatat ccggacttta
    17401 gcaaaagggc gaatttgtgt tcgatgtatg ataaaattga aagaaagacc gaatcaattt
    17461 cataaaactt cttcggatgg aaatctaagt tatgaaattg atttaaaccg agaaactttt
    17521 aatatgttaa gaactggatc cagagaggat ggaacgtagt gagttcgttt gtacatttgc
    17581 atgtgcacag tgaatacagc ctgctcgacg gcgccgcgcg tatccatgat cttacggagc
    17641 gggcggcgga actgggcatg tccgctcttg ccctgaccga tcacggggtt atgtacggca
    17701 caattgcttt ttataaagcc tgcaaacagc gtgggatcaa gccgatcata gggtgtgagg
    17761 tttatttcac cacgggctct atcaggcaga agggcaatcg gcaggagcag cctatctatc
    17821 atctgatcct ccttgccaag aataatacgg gttaccgtaa tttaatgaag ctgtgctcca
    17881 ttggacattt ggaaggattc cattataaac cgcggattga cgccgagcat ctggcagccc
    17941 attcggaagg gctgatctgt ctgagtgcct gccttggcag tgaagtatcc cagcatttgc
    18001 tccacgaccg caaagaagac gcaaggaagg ccgccgaacg ttaccgttct atatttggtg
    18061 aggattttta tctggagatt caggatcacg gcatgatgga gcagaagaaa gtcatgcaca
    18121 gtatgattga attgagccgt gaaaccggca taccgcttat tgcaaccaat gacgtccatt
    18181 acgtgcggga acctgatcat gaagtgcagg atgttctgat ttgtatcggt acaggcaaaa
    18241 cagtagagga cgaggacaga ttgaagatgg ggacaagtca gctctatctg aaaacccggg
    18301 aagcaatggc cgctttattc gcccatgtgc ccgaggctgt cttaaatacg gaaaaagtgg
    18361 cagcccaatg ccaggtggaa attgaattag gacattctat cctgccaagt tttgaaccta
    18421 ttccggaatc tcttacagcg gcggaatatc tgaaacagct ttgcctggaa ggaatttcag
    18481 ggcgctatgg aacccgtcaa gagtggaatg acccgtcttc ggatttccgc aagcaagtgg
    18541 aacaaaagct ttattatgaa ttggatgtta ttgaaagcat gggattctcg gattacttcc
    18601 tcatagtatg ggactttatc cggtatgccc atgaacaggg aatcatgacc ggcccgggca
    18661 ggggatcctc tgcagggagc cttgtcgcct atgcattgaa tattaccgat gtagatccca
    18721 ttgagtataa cctgctgttc gagcggttcc ttaatcccga acggatcacc atgcctgata
    18781 ttgatataga ttttaatgat gaaaggcggg acgaagtcat tgattacgta gtacgtaaat
    18841 acggcaagga acgtgtagcc cagattatta ctttcgggac catggcggcc aaggctgcgg
    18901 tgcgggatgt gggaagagtc cttaatcttc cttacaatga agtagataaa gcggccaagc
    18961 tgataccaaa ccatctgggc atgacaattg accatgcgct tgaagtgaac agcgatcttc
    19021 gcgagcttgc ggaaaagcag ccaaaaacag cggaattgct gaatatggca aaacgtgtcg
    19081 aaggcatgcc ccgacatgct tcgactcacg ccgcgggggt tgtcatttcc cgtgatcctc
    19141 ttaccgatta tgttccgctc caggaaggaa ctgaacaaac acccctgacg cagtattcca
    19201 tggagcattt ggaatccata ggattgctga agatagattt cctcgggctc cgtaccttat
    19261 ccattatcga acgtacactt gcctggatca aggagcagga agggaagctg gtcgattgga
    19321 cacagacgga caagagtgac cctaaaacgt atgagcttct cagcagaggc gaaacaaccg
    19381 gtgtgtttca gcttgaatcc cccggtatgc gccgggtatt gaaggagctt aagccgtcac
    19441 ggtttgagga catcatttcc gtactcgccc tgtaccgtcc aggaccgatg gagtttatcc
    19501 cgcagtatat tgcctgcaaa cataaacaga cggaaccggt ttatccgcac ccctccttgg
    19561 agacgatttt gaaagatacg tacggcatta tcgtgtatca ggaacagatt atgcagattg
    19621 cctccaggat ggcgggattc agcctgggtg aagcggattt gctgcgccgg gccgtatcta
    19681 agaaaaaacg tgaggtactg gatgagcagc gttcccactt tgtagaggga agccttggcc
    19741 aaggctttac tgcagaggag gcgaatcatg tctatgatat gatcgtccgt ttcgcggact
    19801 atggctatcc gcgtgcgcac gcgaccgcat acggtgtact cgccttccag acggcttatc
    19861 tgaaggcaca ttatccaagg catttcatgg catccatgct gacagcggta accgggaacc
    19921 aacgtaaaat ggcagaatat gtcgatgagt gcagacgaat gaagctggat gtgcttcctc
    19981 cggatattaa tgagagcgga gtgctcttca ctccggttgc ttctccgggg tttggtacgg
    20041 agcctgcccg gtacgccggc gagccggcag aggaggggat ggcggataaa atccccgtga
    20101 atggagccat ccgctttggg cttgcggcca tcaagaatgt tggagcaagc gccattgaag
    20161 cggtgctcaa ggagcggcgc aaagagacgt ttacgagcct gcttgatttt tgccggcgcg
    20221 ttgatctgcg tatctgcaat aagcgtgtca ttgaatcatt gattcaagcc ggcgcgtttg
    20281 acacgctgcc gggtcataga gcccagcttg tggccatgct tgatgatacg gcggaggcgg
    20341 cactaaagtg gaggaaagag aaggacgatc tccagctgca cttgttcggc tttgtagaag
    20401 agccgcattg ggaggtagag gtccctgacg tgccgatgct gactaagctg cagcagctgg
    20461 attacgagcg ggaattgatc ggaatgtact tgtccggcca tccgctcgat gcgcatgagg
    20521 atctattggg caggctggaa gcagatccgc tttaccaact gcaagagtat cccgatcaca
    20581 gtgaagtggt tgtggcaggc atggtcgcat ccagcaagac catcgtgacc aaaagagggg
    20641 aaccgatggc ctttatggag ctggaagacc ggattgccaa agtagagatc gtccttttcc
    20701 ccaaagtatg gaagggggca gctccacttg tccagaaagg acgtgtcgtt tttgtaaagg
    20761 caaagctgca gcaccaggat gaagatatgc ctaaactttt ggcagatgtt gtctgcggtc
    20821 ctgatgatcc ggctatttat cagctttttt ataaaaatgg ggacattagg aaaaatggtg
    20881 ctgttcataa tggccaggta agttttggga agtccgggag ccattcgagg caaaaagttt
    20941 taaccgtgga taatgccggg gaagcgggaa tcgga
//
