LOCUS       NZ_CP020555            21053 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. Sge12 chromosome, complete genome.
ACCESSION   NZ_CP020555
VERSION     NZ_CP020555.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Sge12
  ORGANISM  Streptomyces sp. Sge12
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7983613)
  AUTHORS   Tao,M., Xu,J., Xu,M., Liu,K., Zhao,Z. and Peng,Q.
  TITLE     Genome sequence of Streptomyces sp. Sge12, producing unknown
            compounds against rice blast disease
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7983613)
  AUTHORS   Tao,M., Xu,J., Xu,M., Liu,K., Zhao,Z. and Peng,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, Huashan Road 1954, Shanghai 200030,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: RS_HGAP Assembly v. 3; BWA v. 0.7.10; Bowtie v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 85.0x
            Sequencing Technology :: Illumina HiSeq 4000; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:12:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,312
            CDSs (total)                      :: 7,216
            Genes (coding)                    :: 7,106
            CDSs (with protein)               :: 7,106
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 32 of 111
            Pseudo Genes (incomplete)         :: 91 of 111
            Pseudo Genes (internal stop)      :: 8 of 111
            Pseudo Genes (multiple problems)  :: 18 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:35:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2841467
            Orig. end                         :: 2862520
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020555.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="26"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11053)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    19..32
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.1"
                     /tool="antismash"
     gene            278..1480
                     /locus_tag="B6R96_RS12235"
                     /old_locus_tag="B6R96_12235"
     CDS             278..1480
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266483.1"
                     /locus_tag="B6R96_RS12235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12235"
                     /product="NADP-dependent malic enzyme"
                     /protein_id="WP_081522483.1"
                     /transl_table=11
                     /translation="MAAEIFNPRSDSVTDNNPDAVFALHRGGKMAIQATVPVTNKDDLS
                     LAYTPGVAKVCSAIAEQPELVNEYTWKSNVVAVVTDGTAVLGLGDIGPEASLPVMEGKA
                     ILFKQFGGVDAVPIALATKDTDEIIETVIRLAPSFGGVNLEDISAPRCFEIERRLQEAL
                     DIPIFHDDQHGTAIVTLAALRNAAKLTGRTLGDLRAVISGAGAAGIAIAKILVDAGIGD
                     VCVTDRKGVVSADRSDLTDVKAEIAGLTNRTGQTGSLETALNGADVFIGVSGGTVPEAA
                     VASMAKDAFVFAMANPNPEVHPDVAHKYAAVVATGRSDFPNQINNVLAFPGIFAGALKV
                     RATRITEGMKIAAADAIAGVVGDELAADYVIPSPFDERVAEAVATAVAAAAKADGVARL
                     V"
     misc_feature    complement(306..318)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: strong, score: 25.59"
                     /tool="antismash"
     gene            1622..2584
                     /locus_tag="B6R96_RS12240"
                     /old_locus_tag="B6R96_12240"
     CDS             1622..2584
                     /NRPS_PKS="Domain: PKS_ER (17-318). E-value: 6.2e-35.
                     Score: 112.8. Matches aSDomain:
                     nrpspksdomains_B6R96_RS12240_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966331.1"
                     /locus_tag="B6R96_RS12240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12240"
                     /product="quinone oxidoreductase"
                     /protein_id="WP_030385999.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.6e-20, bitscore:
                     70.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAAYAARIDRDQPLNGLELGDRPAPEARPGWVTVNVKAASLNHH
                     DLWSLRGVGLGEERLPMILGCDAAGIDQDGNEVVLHSVIGQSGHGVGPDEPRSILTERY
                     QGTFAEQVTVPAWNVLRKPAELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAG
                     GGVATAAIALGKAAGLRVFATSRDEAKRKRAVELGAVEAYEPGARLPQRVDAVIETVGA
                     ATWSHSVKSLRPGGTLVISGATSGDRPAHAELTRIFFLELKVVGSTMGSKDELEDLLAF
                     CATTGLRPVIDEVLPLDRAREGFEKLASGDLFGKIVLTP"
     aSDomain        1673..2575
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B6R96_RS12240_PKS_ER.1"
                     /evalue="6.20E-35"
                     /label="B6R96_RS12240_PKS_ER.1"
                     /locus_tag="B6R96_RS12240"
                     /protein_end="318"
                     /protein_start="17"
                     /score="112.8"
                     /tool="antismash"
                     /translation="LELGDRPAPEARPGWVTVNVKAASLNHHDLWSLRGVGLGEERLPM
                     ILGCDAAGIDQDGNEVVLHSVIGQSGHGVGPDEPRSILTERYQGTFAEQVTVPAWNVLR
                     KPAELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAGGGVATAAIALGKAAGLR
                     VFATSRDEAKRKRAVELGAVEAYEPGARLPQRVDAVIETVGAATWSHSVKSLRPGGTLV
                     ISGATSGDRPAHAELTRIFFLELKVVGSTMGSKDELEDLLAFCATTGLRPVIDEVLPLD
                     RAREGFEKLASGDLFGKIVL"
     CDS_motif       2012..2050
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B6R96_RS12240_0001"
                     /evalue="5.60E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="B6R96_RS12240"
                     /protein_end="143"
                     /protein_start="130"
                     /score="13.4"
                     /tool="antismash"
                     /translation="AACLPTAWLTAYR"
     CDS_motif       2081..2140
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B6R96_RS12240_0002"
                     /evalue="2.80E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="B6R96_RS12240"
                     /protein_end="173"
                     /protein_start="153"
                     /score="16.7"
                     /tool="antismash"
                     /translation="GDSVLVQGAGGGVATAAIAL"
     gene            2633..2842
                     /locus_tag="B6R96_RS12245"
                     /old_locus_tag="B6R96_12245"
     CDS             2633..2842
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312042.1"
                     /locus_tag="B6R96_RS12245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12245"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_030385998.1"
                     /transl_table=11
                     /translation="MTEATDLAERAGDRDPRVGLRAVSALRRLLEQLEAVQVRSARAQG
                     WSWQEIAAELGVSRQAVHKKYGRL"
     gene            2842..3414
                     /locus_tag="B6R96_RS12250"
                     /old_locus_tag="B6R96_12250"
     CDS             2842..3414
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266479.1"
                     /locus_tag="B6R96_RS12250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12250"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_081522484.1"
                     /transl_table=11
                     /translation="MFERFTRDARSTVTGAVTEARRSGAATVTEEHLLLSLLTLGALDP
                     LGVDRAAVAADLTAARRRGGMSRADEEALAGLGIDVTQIVSRIEETHGEGALAAPAPRR
                     RTLGSSLRSVLGREEADGRTGNRHVPFTEGAKKVLEQSLRIALGRKDHHIGTLHLLLAL
                     LSRPGTVSEVLTDHGITYRTAETTLAA"
     gene            complement(3598..4563)
                     /locus_tag="B6R96_RS12255"
                     /old_locus_tag="B6R96_12255"
     CDS             complement(3598..4563)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313664.1"
                     /locus_tag="B6R96_RS12255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12255"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_081522485.1"
                     /transl_table=11
                     /translation="MPPVFAHGRLRLYLLKLLDEAPRHGYEVIRLLEERFQGLYAPSAG
                     TVYPRLAKLEAEGLVTHATEGGRKVYSITEAGRAELADRGGELADLELEIRDSVTELAA
                     EIRSEVRGAAGDLRREMQAAASASATRTTEEESWQTAKEELRKARQEWKEQARRAKDES
                     RRAREEAQQARRQAKEAQERAREEVQRIAVQLQEQFARSGGVLGSLAGAWLGGTPAAGS
                     AGSAGAGAGAGAGAAAKGAGAADAWADAAGDADRASEWAADLTATGDPARDLDRLLDRF
                     RDEVRDAARDRGVTEAQVAEARRHLEAASARLGTTFGARP"
     gene            complement(4565..5524)
                     /locus_tag="B6R96_RS12260"
                     /old_locus_tag="B6R96_12260"
     CDS             complement(4565..5524)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741545.1"
                     /locus_tag="B6R96_RS12260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12260"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_053703972.1"
                     /transl_table=11
                     /translation="MAEQSPESPQPSPAPSTWHFAEPRKLTFEEPVTELRVRVVSGTVN
                     VVAAEEGPARLEVTEVEGPPLYVVQDGGTLTVSYEDAPWNGSHGLKEWFESKPWKAWSG
                     SFSGRKAWERSAAITLSVPAGTHVRVAAVDAASFVSGISGGTDVNGVSGDATLVGLSGR
                     VKAHTVSGSVEAQSVTGEFGFHSVSGSLTVVDGAGVKVRADSVSGDMLIDLDPGPEGSA
                     PVDIALNSVSGQVAIRLPHPADARVEANTATGRVSNAFEDLRVSGQLGAKRITGTLGSG
                     AGTLRATTVSGSIALLRRPQSEADTPAAAPLTLDKKVL"
     misc_feature    complement(5580..5598)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.33"
                     /tool="antismash"
     gene            5679..6488
                     /locus_tag="B6R96_RS12265"
                     /old_locus_tag="B6R96_12265"
     CDS             5679..6488
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966322.1"
                     /locus_tag="B6R96_RS12265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12265"
                     /product="hypothetical protein"
                     /protein_id="WP_203351723.1"
                     /transl_table=11
                     /translation="MSRTVTGGLLLCRAEPLAVRRPAHLLRVRLLLAPAGEWSVLVPED
                     KPWRDGRESVAEVLSGWGSALALGADWPVLSLWWEDGRTGFALSSGFRRTAAHAWDAAG
                     RPDGEPGAMRALSARLGLDPVLDLADLERLTRADADPAVDGEGRLLALVALLTRAGLAL
                     PAGLAPGEPADRLRGAARVAPGVETVEWSGWRDAVRAELDAVEGSPAGPWIHGPRARLL
                     GAAQVAAGAPLLAWAAHRRSPGWATAGAVLLAQGAAVLAYDRARARR"
     gene            complement(6505..7440)
                     /locus_tag="B6R96_RS12270"
                     /old_locus_tag="B6R96_12270"
     CDS             complement(6505..7440)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889347.1"
                     /locus_tag="B6R96_RS12270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12270"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_030385993.1"
                     /transl_table=11
                     /translation="MELEVRHLRALCAIADAGSLHKAARQLGVSQPSLTTQLRRIERAL
                     DGELFLRERTGCRPTPFGRTVLGRARPLLAEMAALVAEARELAHASRLRIGSTASSALP
                     GWLRRIHRRLPDTETSLVVDVSANALLRMVAAGQLDVAFVHEVEGSPLRVPPELELRVL
                     MEREPQFVSMSRDHPAAGQAVVSLRDLAADRWMVDPSVDGEWDGLRRVFAGAGLDPPVL
                     HADYHTATSLIISGEAVAPCQPTSGPREDMAIRPLCGDPLAVRLLLATRPGAHAEVYED
                     LRAAYREAALRTPPYRAWLHHHASPLLEVA"
     misc_feature    complement(6880..6882)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7651..8319
                     /gene="snpA"
                     /locus_tag="B6R96_RS12275"
                     /old_locus_tag="B6R96_12275"
     CDS             7651..8319
                     /EC_number="3.4.24.77"
                     /codon_start=1
                     /gene="snpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266475.1"
                     /locus_tag="B6R96_RS12275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12275"
                     /product="snapalysin"
                     /protein_id="WP_081522487.1"
                     /transl_table=11
                     /translation="MRHSRKAMLATTVGLGLAAALGVAPTATAAPAPVGSAVSYAAYDR
                     SPENEAANRAFFEAVQRSVAEQRAANPGVLAVTVTYNTRSAPSFRTQIARSTQIWNSSV
                     SNVKLQEVSSGGNFSYREGNDSRGSYASTDGHGRGYIFLDYRQNQQYNSTRVTAHETGH
                     VLGLPDHYSGPCSELMSGGGPGTSCQNANPNSAERARVNQLWANGFASGLGAKDLGAKG
                     "
     gene            complement(8321..8524)
                     /locus_tag="B6R96_RS12280"
                     /old_locus_tag="B6R96_12280"
     CDS             complement(8321..8524)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741542.1"
                     /locus_tag="B6R96_RS12280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12280"
                     /product="hypothetical protein"
                     /protein_id="WP_052873807.1"
                     /transl_table=11
                     /translation="MAGEQQHHAHETVAPQAGHEQQACPACGRRVDTVVRRRKSLGIFI
                     PVWGRGPCRNPDCRDYADPEER"
     gene            complement(8561..9148)
                     /locus_tag="B6R96_RS12285"
                     /old_locus_tag="B6R96_12285"
     CDS             complement(8561..9148)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767199.1"
                     /locus_tag="B6R96_RS12285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12285"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_081522488.1"
                     /transl_table=11
                     /translation="MRKLTYFIATSVDGFIGAPDGDGDFFYSHLDAEFVGYLAAEYPET
                     ISAQGRVHLGIADAAPKRFDAVIMGRRTYEPGLAQGMTSPYGHLPEQYVVSRSLTAPPD
                     PQVRLIGGDLAAEVRALKARDGLGIWLCGGADLATQLIDEIDEIIVKTYPVFAGTGMPM
                     SHAGFGVRPLELTGVRTFGGGQVVSTYAVRRS"
     gene            complement(9257..9859)
                     /locus_tag="B6R96_RS12290"
                     /old_locus_tag="B6R96_12290"
     CDS             complement(9257..9859)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741540.1"
                     /locus_tag="B6R96_RS12290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12290"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_081522489.1"
                     /transl_table=11
                     /translation="MALEIRQADQSDRDAVARLLDESFRTDPVSSWVFPDPEHRAAVHG
                     KFLGVFVDVALEEGRIDYAVDGSAAALWLRIPAADPQGEPVEDEVPARMRAVADPDNER
                     CELVGRLTGAVHPTAEEHEYLLMIAVAPGRQGEGLGTELMRPVLERCDREGVPAYLEAS
                     SERSKGLYERLGWEFTGEAVRLPEGPLMWPMWRKPRG"
     gene            complement(10001..11053)
                     /locus_tag="B6R96_RS12295"
                     /old_locus_tag="B6R96_12295"
     CDS             complement(10001..11053)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892050.1"
                     /locus_tag="B6R96_RS12295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12295"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_203351724.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-58, bitscore:
                     196.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVNAIATGEGQDAAALLDRTRQAVDPQLRRTLESLPGSMRRVA
                     MYHFGWEHEDGSPAAGGAGKAIRPALVLAAAQALRGPDAGPADEAVKAAAAVELAHNFT
                     LLHDDIIDKDVRRRGRATAWTVFGTPDAIITGDAMMALALRLLAEDPHPAAAAASARLA
                     ACIIELCAGQQADCAFEQRPEVSLDECLAMATAKTGALLGCACALGALYAGAGLEEVDA
                     MDAFGREAGLAFQLIDDLIGIWGDPGHTGKPAGADLIARKKSLPVVAALTSGTAAGKEL
                     AALYAGPMTGDDVRRAADAVDRAGGRDWAQAEAADRMGRAVQQLSRAVPDLGAAGGLLA
                     LAEFVTRRTR"
     gene            complement(11050..12456)
                     /locus_tag="B6R96_RS12300"
                     /old_locus_tag="B6R96_12300"
     CDS             complement(11050..12456)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741538.1"
                     /locus_tag="B6R96_RS12300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12300"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_081522490.1"
                     /transl_table=11
                     /translation="MSVQAGSESEAQTPQRSLGTTAARNLATTTKSAPQMQEITSRWLL
                     KMLPWVSVQGGTYRVNRRLSYSVGNGVVEFIKTGTQVQVIPAELGELPLLRDYEDLDVL
                     GELAQRCRQIDFEAGQELTSFGSPADEVFLLAHGRIDQIGPGPYGEDAVLRTVADGAYF
                     GDDSLVDEESIWEYTARAATSGTALTLSRQDFQLLADRVESLRAHVEGVRSRPDRQTNK
                     YGEAAIELSAGHEGEAVLPGTFVDYEARPREYELSIAQTVLRVHSRVADLYNHPMNQTE
                     QQLRLTVEALRERQEHEMLNNRNFGLLHNADYDQRIQPHDGAPSPDDMDQLLSMRRGSK
                     LFLAHPKAIAAFGRECNKRGIYPESVDVGGNRVPAWRGVPIFPSNKIPISDARTTSILC
                     MRTGEDEQGVIGLHQPGIPDEIEPSLSVRFMGISEQAIISYLVTAYFSAAVLVPDALGV
                     LENVEIGRWR"
     misc_feature    12656..12672
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 25.06"
                     /tool="antismash"
     gene            12692..13150
                     /locus_tag="B6R96_RS12305"
                     /old_locus_tag="B6R96_12305"
     CDS             12692..13150
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031657.1"
                     /locus_tag="B6R96_RS12305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12305"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_052873811.1"
                     /transl_table=11
                     /translation="MRLTRFTDLALRVLMRLAIEETDLPTTRDVAATMEVPYTHTAKVV
                     ARLQHLGLVEARRGRGGGLALTSAGRAAPVGSVVRELEGEGDVVDCEGTTPCPLRGACV
                     LRGALRRAQEAFYAALDPLTVNDLVASPTGPLLLGISSRAPTGAGSSP"
     misc_feature    13224..13237
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.96"
                     /tool="antismash"
     gene            13338..14534
                     /locus_tag="B6R96_RS12310"
                     /old_locus_tag="B6R96_12310"
     CDS             13338..14534
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127491.1"
                     /locus_tag="B6R96_RS12310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12310"
                     /product="globin domain-containing protein"
                     /protein_id="WP_081522491.1"
                     /transl_table=11
                     /translation="MLSETSSATVRATLPAVGAAIGEIAELFYTKLFAAHPALIRDLFN
                     RGNQNAGLQKQALAGSVAAFATHLLAHPDTRPDVMLNRIAHKHASLGVTREQYAVVHRH
                     LFEAIAEVLGEAVTPEVARAWDEVYWLMANALIALEERLYAEQQVVAGDVWRKWTVTER
                     VAETADCTTFRIAPADGAPAPAHRPGQYVSVQVELPDGARQIRQYSLITSPGSTIRAIT
                     VKRVHGPAAAGPDGEVSHHLHARVRTGDTLRVSAPYGDLVLADSAAPVLLASAGIGCTP
                     MLSMLEHLADTGHTAPVTVLHADRSPADHPLRGDHRALTHKLADASARFWYEEAAEPGD
                     GQGRMDLSAVALAPGTRAYLCGPLPFMRAVREQLIAKGLPAADIHYEVFGPDLWLASV"
     gene            14662..15252
                     /locus_tag="B6R96_RS12315"
                     /old_locus_tag="B6R96_12315"
     CDS             14662..15252
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154135.1"
                     /locus_tag="B6R96_RS12315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12315"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_184791660.1"
                     /transl_table=11
                     /translation="MAAPMSADRFINALRNEGLTVVEVGAWRTHNRNHKGPWGPVHGVM
                     IHHTVTRGTAHTVELCREGHSALPGPLCHGVIAKDGRVHLVGYGRANHAGAGDSDVLAA
                     VIAEKRLPPDNETDTDGNRHFYGFECENLGDGEDPWPAVQLDAIARAAAALCRVHHWTA
                     RSVIGHREWQPGKVDPRGFTMDAMRARIGERLK"
     gene            15295..16188
                     /locus_tag="B6R96_RS12320"
                     /old_locus_tag="B6R96_12320"
     CDS             15295..16188
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266466.1"
                     /locus_tag="B6R96_RS12320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12320"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_053703966.1"
                     /sec_met_domain="PALP (E-value: 3e-19, bitscore: 68.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPELLPRPPSALVEAADDRFERYGVRLLLKRDDLVHPQLPGNK
                     WRKLAPNLRAALAGGHDQLLTFGGAYSNHLRATAAAGRLLGLRTVGVVRGDELAGRPLN
                     DSLARCAADGMRLHFVSRSEYRRKAEPDRLARLVDAAGARGAYVVPEGGSNALALAGCA
                     ELGRELRGAADVVAVACGTGGTLAGLAAGLGPGQRALGVPVLAGGFLAAEIRSLQAAAF
                     GGPAGDWTLAEDFHHGGYARVPAALEAFAADFASRHGLPVERIYVAKLLWALTELTASG
                     AFPPGTTLAAVVTGRP"
     gene            complement(16229..17809)
                     /locus_tag="B6R96_RS12325"
                     /old_locus_tag="B6R96_12325"
     CDS             complement(16229..17809)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105585.1"
                     /locus_tag="B6R96_RS12325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12325"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_081522492.1"
                     /transl_table=11
                     /translation="MEVLPLVALIAGSAAVAGLARRTPVPAPLLLVVFGLLAGYVPGVP
                     AYTLDPHIVLPLLLPPLLYTAAVDSSYLDLRANIRPIAMLSVGYVLFATLAVGYAAYLL
                     VPGLTMPVALVLGAVIAPPDAVAATAIARKLRLPNRITTILQGESLVNDATAITAYKVA
                     LAAAVGVSAGWAGGIAEFLLASVGGIGVGLLLMVPIHQLRTRLKEPLLQNTLSLLIPFV
                     AYAAAERVHASGVLAVVVVALYLGHRNWQVDFATRLQEEAVWRVVAFVLESVVFALIGL
                     QLPVVLGGLGEYDGMHAATYAVAVFLAVVVARFLWVFPATFVPRWLSERIRARESDTDW
                     KAPVIVGWAGMRGVVSLAIAFSVPMSVPHRNLILFLTFTTVIGTLVVQGLTLPPLIRAL
                     NLPPKDVQAETLAEAQAQSEASRAAEERLAELLEEPESSTLPPPLADRLRTVLERRRNA
                     VWERLGEVNPETGESADDIYRRLAREMIAAEREVFVTLRDQRRIDDEMLRALLRRLDLE
                     EAAAYREEG"
     misc_feature    complement(17857..17871)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            18022..18282
                     /locus_tag="B6R96_RS12330"
                     /old_locus_tag="B6R96_12330"
     CDS             18022..18282
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="B6R96_RS12330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12330"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_030385976.1"
                     /transl_table=11
                     /translation="MSECTHVAELPRPEPVPSHDTCSECLALGSHPVQLRMCLGCGHVA
                     CCDSSPHRHATAHHRETGHPVMRSFEPGETWRWCFVDGSIV"
     gene            18488..18901
                     /locus_tag="B6R96_RS12335"
                     /old_locus_tag="B6R96_12335"
     CDS             18488..18901
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="B6R96_RS12335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12335"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_030012703.1"
                     /transl_table=11
                     /translation="MSQIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLIDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVEATVEENRTVSISLYKQRGAGPGPA"
     gene            18898..19938
                     /locus_tag="B6R96_RS12340"
                     /old_locus_tag="B6R96_12340"
     CDS             18898..19938
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266462.1"
                     /locus_tag="B6R96_RS12340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12340"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_203351619.1"
                     /transl_table=11
                     /translation="MSGGEIPVRGGDRPRVRHEVDGGIPEQQHARPHPADADAEDGFLD
                     SAERRAGPMSENQQEQPQPSRPTEATAPAAPVVPAVPAAPVFPVTPALPDPRDRSGARA
                     LFIELRALPDGSVEKAELRNRLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSV
                     DRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLSLTTATAELSQQHG
                     RSPTVHELAERLGISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLGAEDEALEG
                     VEYRESLKPLLEGLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLRD
                     KLLVEE"
     gene            complement(19988..20449)
                     /locus_tag="B6R96_RS12345"
                     /old_locus_tag="B6R96_12345"
     CDS             complement(19988..20449)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741528.1"
                     /locus_tag="B6R96_RS12345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_12345"
                     /product="hypothetical protein"
                     /protein_id="WP_053703965.1"
                     /transl_table=11
                     /translation="MSKKQPANAPAPAADPSAAPPAALPGRLTAAAALTALEGLALAGL
                     GLYMLFVGIAGDPDSPQQAETGGITLLALAALPLIAARGLRLGRRWSRGPALITQLMAL
                     PVAWTLYSTGGAMIAAAVALALAAVAVVALLVNPTATEALGIGPGEQAR"
ORIGIN
        1 tcggacagca aggtttggac ttttcgccaa aagccgggca agggacctac agttgagcgg
       61 gaatcgactc gtctgggcga gcgttcttcg ggtagaacag atccttacac ccctcatccg
      121 gggctcaggg cgcgcgtgcg gcgcgcccgc gcgtacgaac ctccccttcg cggagacggg
      181 ccaaccgtcg acgcggagta cggacgcggt gcccgcccac cccttaacca ggagtggcca
      241 ccctcaacga ttcaaaggac ttaaggggtc acacgaagtg gcagcggaga tcttcaaccc
      301 tcgcagtgac agcgtcacgg acaacaaccc ggacgcggtg ttcgcgctgc accggggcgg
      361 caagatggcc atccaggcca cagtgccggt caccaacaag gatgaccttt ccctcgcgta
      421 cacgcccggc gtggcgaagg tgtgcagcgc catcgccgag cagccggagc tggtgaacga
      481 gtacacctgg aagtccaacg tggtcgccgt cgtcaccgac ggtacggccg tgctcggact
      541 cggtgacatc ggtcccgagg cctccctccc cgtcatggag ggcaaggcca ttctcttcaa
      601 gcagttcggt ggtgtggacg cggttccgat cgcgctcgcc accaaggaca cggacgagat
      661 catcgagacg gtcatccgtc tcgctccgtc cttcggcggg gtgaacctgg aggacatctc
      721 cgccccccgc tgcttcgaga tcgagcgccg cctccaggag gcgctggaca tcccgatctt
      781 ccacgacgac cagcacggca cggccatcgt gacgctggcc gcgctgcgca acgcggcgaa
      841 gctgacgggt cgcaccctcg gcgacctgcg cgccgtgatc tcgggcgccg gcgccgccgg
      901 tatcgccatc gcgaagatcc tggtggacgc gggcatcggc gacgtctgcg tcaccgaccg
      961 caagggcgtc gtgtccgcgg accgctccga cctgacggac gtcaaggcgg agatcgcggg
     1021 cctgaccaac cggaccggcc agaccggctc cctggagacg gccctgaacg gggcggacgt
     1081 cttcatcggc gtctccggcg gcacggtccc ggaggcggcg gtggcctcga tggcgaagga
     1141 cgcgttcgtc ttcgccatgg ccaacccgaa cccggaggtc cacccggacg tcgcgcacaa
     1201 gtacgcggcg gtcgtggcca cgggccgctc ggacttcccg aaccagatca acaacgtgct
     1261 ggcgttcccg ggcatcttcg cgggcgccct caaggtgcgc gccacccgga tcaccgaggg
     1321 catgaagatc gccgccgccg acgccatcgc cggcgtcgtg ggtgacgagc tcgccgccga
     1381 ctacgtgatc ccgtcgccgt tcgacgagcg cgtcgccgag gccgtcgcca cggccgtcgc
     1441 cgccgcggcg aaggccgacg gcgtggcccg cctggtctga caccggaccc gagcagtacc
     1501 cgcagaggcc cgaccggagc gatccggccg ggcctctgcc gtatccggca ccgggggccg
     1561 acccggccgt gtgacgggaa cgggggtgga tgccggggct accgagcggt agcgtcgccg
     1621 catgttcgct gcctacgccg cccgaatcga ccgtgaccag ccgctgaacg gccttgagct
     1681 gggcgaccgc ccggctcccg aggcccgacc cggctgggtg accgtgaacg tcaaggccgc
     1741 ctccctcaac caccacgacc tctggtcgct gcgcggggtc ggcctcggcg aggaaagact
     1801 cccgatgatc ctcggctgcg acgccgccgg gatcgaccag gacggcaacg aggtcgtcct
     1861 gcactccgtg atcggccaga gcggccacgg ggtcggcccg gacgagcccc gctcgatcct
     1921 caccgagcgc taccagggga ccttcgccga gcaggtgacc gtccccgcct ggaacgtgct
     1981 gcgcaagccc gccgagctga gcttcgagga ggccgcctgc ctcccgacgg cctggctgac
     2041 ggcgtaccgg atgctgttca ccaatgccgg ggtccgcccc ggggactccg tactcgtcca
     2101 gggcgccggc ggcggtgtcg cgaccgccgc gatcgccctc ggcaaggcgg ccggcctgcg
     2161 ggtcttcgcg acgagccggg acgaggccaa gcgcaagcgg gccgtggagc tgggtgcggt
     2221 agaggcgtac gagccgggcg cgcggctgcc gcagcgggtg gacgcggtga tcgagacggt
     2281 gggcgccgcc acctggtccc actcggtgaa gtccctgcgc cccggcggca ccctggtgat
     2341 ctccggcgcc acgagcggcg accgcccggc gcacgccgag ctgacccgga tcttcttcct
     2401 ggagctgaag gtggtgggct ccaccatggg ctcgaaggac gagctggagg acctcctcgc
     2461 cttctgcgcg accaccgggc tgcggccggt catcgacgag gtgctgccgc tggaccgggc
     2521 acgggagggg ttcgagaagc tcgcgtcggg cgacctcttc gggaagatcg tcctcacccc
     2581 ctgacgtcaa ccggggttga cgaacctccc gcgtcaacct acattgacat gcatgaccga
     2641 agccactgat ctcgccgagc gggccggtga ccgtgacccg cgcgtgggcc tgcgtgccgt
     2701 gtccgccctc cgcaggctgc tggagcagct ggaggccgta caggtacgca gcgcccgcgc
     2761 gcaggggtgg tcctggcagg agatcgcggc cgagctcggc gtcagccggc aggccgtgca
     2821 caagaagtac gggaggctct gatgttcgaa cgcttcaccc gcgacgcccg ctcgaccgtg
     2881 accggggcgg tgaccgaggc ccgccgcagc ggcgccgcca ccgtcaccga ggaacacctg
     2941 ctgctgtccc tactgaccct gggcgccctg gaccccctcg gggtggaccg cgcggcggtg
     3001 gccgccgatc tcacggcggc ccgccgccgg ggcggcatgt cgagggcgga cgaggaggcg
     3061 ctggccggcc tcggcatcga cgtcacccag atcgtctccc gcatcgagga gacccacggc
     3121 gaaggcgccc tcgcggcccc ggcgccccgc aggcggaccc tgggctcctc gctccgctcg
     3181 gtcctcgggc gcgaggaggc ggacggccgc accggcaacc ggcacgtccc cttcaccgag
     3241 ggggcgaaga aggtgctgga gcagtccctg cgcatcgccc tgggccgcaa ggaccaccac
     3301 atcggcaccc tgcacctgct gctggcgctg ctctcccgcc ccggcacggt ctccgaggtc
     3361 ctgacggacc acggcatcac ctaccgcacg gccgaaacca ccctggccgc ctgaccccac
     3421 ccctccagcc ccgccggcgt ttgaggggcg gggttccgta ggcggagccc cgcccctcca
     3481 gccccgccgg cgtttgaggc gcggggtccg gggcggagcc ccggctgccc ttcagcctcg
     3541 ccggcgtttg aggcgcgggg tccggggcgg agccccggca gcggtgccgc ggggaggcta
     3601 cggccgggcc ccgaacgtgg ttcccagccg ggcggaggcc gcttcgaggt gccgacgggc
     3661 ctcggccacc tgggcctcgg tcaccccgcg gtcccgcgcc gcgtcgcgca cctcgtcgcg
     3721 gaagcggtcg agcagccggt ccaggtcacg ggccgggtca ccggtggccg tcagatccgc
     3781 ggcccactcg gaagcccggt ccgcgtcccc cgccgcatcc gcccaggcgt ccgccgcacc
     3841 cgcccccttc gccgccgcac cggcaccggc acccgcaccg gcacccgccg agcccgccga
     3901 gcccgccgca ggcgtaccgc cgagccaggc ccccgccagg ctgcccagga ctccgccgga
     3961 cctcgcgaac tgctcctgaa gctggaccgc tatccgctgg acctcctcgc gggcccgctc
     4021 ctgggcctcc ttggcctggc ggcgggcctg ctgcgcctcc tcgcgggcgc ggcggctctc
     4081 gtccttggcc cggcgcgcct gttccttcca ttcctgccgc gctttgcgca gctcctcctt
     4141 ggcggtctgc caggactcct cctcggtggt ccgggtcgcc gacgcggagg ccgccgcctg
     4201 catctcgcgc cgcaggtcac cggccgcgcc ccggacctcg ctgcggatct cggcggccag
     4261 ttcggtgacc gagtcgcgga tctccagttc gaggtcggcg agttcgccgc cgcggtcggc
     4321 caactcggcg cggcccgcct cggtgatgga gtacaccttg cgcccgccct cggtggcgtg
     4381 cgtgaccagg ccctcggcct ccagcttcgc cagccgcggg tacacggtgc cggcggaggg
     4441 cgcgtacagg ccctggaagc gctcctccag caggcggatc acctcgtacc cgtggcgcgg
     4501 ggcctcgtcc agcagcttga ggaggtacag gcgcaggcgg ccgtgggcga agacgggcgg
     4561 catgtcagag caccttcttg tcgagcgtga gcggggcggc ggcgggggtg tcggcctcgg
     4621 actgcgggcg gcgcagcagc gcgatcgagc cggagaccgt ggtggcccgc agggtgcccg
     4681 cgccggagcc gagggttccg gtgatccgct tggcgcccaa ctggccggag acccgcaggt
     4741 cctcgaaggc gttggagacg cggcccgtgg cggtgttggc ctccacgcgg gcgtcggcgg
     4801 ggtgcgggag gcggatcgcg acctggccgg agacggagtt cagcgcgatg tccacgggcg
     4861 cggagccctc cgggccgggg tccaggtcga tgagcatgtc accgctgacg gagtcggcgc
     4921 gcaccttcac gcccgcgccg tcgaccacgg tcaggcttcc ggacaccgag tggaagccga
     4981 actcgccggt gacggactgg gcctcgacgc tgccggacac ggtgtgcgcc ttcacccggc
     5041 cggacaggcc gaccagcgtg gcgtcgccgg agaccccgtt gacgtcggtg cctccggaga
     5101 tcccggagac gaaggaggcg gcgtcgacgg cggccacgcg gacgtgggtg ccggcgggga
     5161 cggagagggt gatcgcggcg ctgcgctccc aggccttgcg gccggagaac gaaccggacc
     5221 atgccttcca gggcttggac tcgaaccatt ccttgagccc gtgggagccg ttccagggcg
     5281 cgtcctcgta ggagacggtc agcgtgccgc cgtcctgcac cacgtacagg ggcggtcctt
     5341 cgacctcggt cacctccagg cgggccgggc cctcctcggc ggcgaccaca ttgacggtgc
     5401 cgctcacgac acggacgcgg agctcggtca ccggctcctc gaaggtgagc ttccgcggtt
     5461 cggcgaagtg ccacgtcgac ggcgccggtg acggctgggg cgactcgggc gactgctctg
     5521 ccatggtgct gctcctcctc gtgcgtacac ggacctggct cgacgcacgc aacatatcgc
     5581 gtcttctgtt aacacgatat atcgcggtca agggaagtca agcactctcc cgaaaccccg
     5641 ccgtttgggg tgttttgctc tattgtgtgg gcatgtcaat ctcccggacc gtgaccggcg
     5701 gactgctgct ctgccgcgcc gaacccctgg ccgtccgccg cccggcccac ttgttgcgcg
     5761 tccgcctgct gctcgccccg gcgggcgaat ggagcgtgct cgtccccgag gacaagccct
     5821 ggcgggacgg ccgggagagc gtggcggagg tcctctccgg ctggggatcg gccctcgccc
     5881 tcggcgccga ctggccggtg ctgagcctgt ggtgggagga cggccggacc ggcttcgccc
     5941 tgtcgagcgg gttccggcgc accgccgccc acgcgtggga cgccgccggg cgcccggacg
     6001 gcgagcccgg cgcgatgcgg gccctgtcgg cgcgactcgg cctcgacccg gtcctggacc
     6061 tggcggacct cgaacgcctc acccgcgccg acgcggaccc ggccgtcgac ggggagggcc
     6121 ggctgctggc cctggtcgca ctgctgaccc gcgccggact ggccctgccg gccggactgg
     6181 cgccgggcga accggccgac cggctccggg gtgcggcccg ggtggccccc ggcgtcgaga
     6241 cggtggagtg gtcgggctgg cgcgacgcgg tgcgggccga gctcgacgcg gtggagggga
     6301 gcccggcggg cccgtggatc cacgggccga gggcccggct gctgggcgcg gcccaggtcg
     6361 cggccggcgc accgctgctg gcctgggccg cgcaccgccg cagtccgggc tgggccacgg
     6421 cgggcgcggt cctgctggcg cagggggcgg cggtcctcgc ctacgaccgg gcacgcgcgc
     6481 ggcgctgacc ggcggaatcc gccgctacgc cacctccagg agcgggctcg cgtggtggtg
     6541 gagccaggcg cggtacgggg gcgtgcgcag cgcggcctcg cggtaggccg cgcgcaggtc
     6601 ctcgtagacc tcggcgtgcg cgccgggccg ggtcgccagg agcaggcgta cggcgagggg
     6661 gtccccgcac agcggccgga tcgccatgtc ctcgcgcggc ccggaggtcg gctggcaggg
     6721 cgcgaccgcc tcgccggaga tgatcagcga ggtcgccgtg tggtagtcgg cgtgcaggac
     6781 gggcgggtcg agcccggccc cggcgaagac ccggcgcagc ccgtcccact cgccgtcgac
     6841 cgagggatcc accatccagc ggtcggcggc gaggtcccgt aaggagacca ccgcctggcc
     6901 ggcggccgga tggtcccggg acatcgacac gaactgcggt tcccgctcca tcagtacgcg
     6961 cagctccagc tcgggcggca cccgcagcgg actgccctcc acctcgtgca cgaacgccac
     7021 gtccagctgc cccgcggcga ccatcctgag cagcgcgttg gcggagacgt ccaccaccag
     7081 cgaggtctcg gtgtccggca gcctgcggtg gatccgccgc agccagcccg gcagcgcgct
     7141 gctggcggtg gagccgatgc gcagcctcga tgcgtgggcc agttcgcggg cctccgcgac
     7201 cagcgcggcc atctcggcga gcagcgggcg ggcccggccc agcacggtcc ggccgaaggg
     7261 ggtgggccgg cagccggtgc gctcgcgcag gaacagctcg ccgtcgaggg cccgttcgat
     7321 acggcggagc tgggtcgtca gggagggctg gctcacgccg agttgccggg cggccttgtg
     7381 caggcttccg gcgtcggcga tggcgcacag ggcgcgcagg tgcctgacct caagctccat
     7441 gccctgaggg taggccggtc cctatggacc gcaccagcca ccgatagccc cccgaatccc
     7501 gccattctca cgctagttgg tcttccgaaa tcttcccgat aggcccgcgc tatcggggac
     7561 tgacatcatc cgccgggcac ttgtgctccc gcagactccg gtaccgaaag accacccccc
     7621 accgcaccgg acgagtagga gctcccccac atgcgccact cccgtaaggc catgctggcc
     7681 acgaccgtcg gcctcggcct cgcagccgcc cttggtgtcg cccccaccgc caccgccgcg
     7741 cccgcccccg tcggcagcgc cgtgagctac gccgcgtacg accgctcgcc ggagaacgag
     7801 gccgccaacc gcgccttctt cgaggccgtg cagcgttcgg tcgccgagca gcgcgccgcc
     7861 aaccccggcg tcctggccgt gaccgtcacg tacaacaccc gcagcgcccc gagcttccgc
     7921 acccagatag cccgctccac gcagatctgg aacagctcgg tgtccaacgt gaagctgcag
     7981 gaggtgtcct cgggcgggaa cttctcctac cgcgagggca atgactcacg cggctcgtac
     8041 gcgagcacgg acgggcacgg ccggggctac atcttcctcg actaccggca gaaccagcag
     8101 tacaactcca cccgggtgac cgcgcacgag accggccacg tgctgggcct gccggaccac
     8161 tactcgggcc cgtgcagcga gctgatgtcg ggcggcggcc cgggcacctc gtgccagaac
     8221 gccaacccga actccgccga gcgggcgcgg gtcaaccagc tctgggccaa cggcttcgcc
     8281 tcgggcctgg gcgcgaagga tctcggcgcc aagggctgag tcaccgctcc tcggggtccg
     8341 cgtagtcacg gcagtcgggg ttccggcagg gaccccggcc ccacaccgga atgaagatcc
     8401 cgagggactt gcgccgcctg accactgtgt cgacgcggcg accgcacgcc gggcacgcct
     8461 gctgctcgtg cccggcctgc ggggccaccg tctcgtgcgc gtggtgctgc tgttcaccgg
     8521 ccatacctcc acggtaggcc ggttccgtgc gttcggcggg tcagctccgg cggacggcgt
     8581 acgtgctgac gacctggccg ccgccgaagg tcctgacccc ggtcagttcc agggggcgca
     8641 ctccgaagcc ggcgtgcgac atcggcatgc cggtgcccgc gaagaccggg taggtcttga
     8701 cgatgatctc gtcgatctcg tcgatcagct gggtggcgag gtcggcaccg ccgcagagcc
     8761 agatgccgag gccgtcccgg gccttgaggg cgcggacctc ggcggcaagg tcgccgccga
     8821 tcagccggac ctgcgggtcg ggcggcgcgg tgagggagcg ggagacgacg tactgctcgg
     8881 gcaggtggcc gtaggggctg gtcatgccct gggcgaggcc cggctcgtag gtgcgccgtc
     8941 ccatgatcac cgcgtcgaag cgcttggggg cggcgtcggc gatcccgagg tggacgcgtc
     9001 cctgggccga gatggtctcg gggtattcgg ccgccaggta cccgacgaac tccgcgtcga
     9061 ggtggctgta gaagaaatcg ccgtcgccgt ccggggcacc gatgaacccg tcgacggagg
     9121 tggcgatgaa gtacgtgagc ttgcgcaagc gattctcttt cggtgggcag tgccaccgca
     9181 ccggggcacg tcgcataaag tacttcacct gaagtggtta cgcaacgact atcgccccgg
     9241 ggcgcggcag cggcgctcag ccgcgcggct tgcgccacat cggccacatc agcggccctt
     9301 cggggagccg caccgcctcc cccgtgaact cccagccgag ccgctcgtac agccccttgc
     9361 tgcgctcact gctcgcctcc aggtacgccg gcaccccctc gcggtcgcac cgctccagca
     9421 ccggacgcat cagctccgta ccgagcccct cgccctgccg gccgggcgcg accgcgatca
     9481 tcaacaggta ctcgtgctcc tcggcggtgg ggtgcaccgc gcccgtgagg cgcccgacca
     9541 gctcgcagcg ctcgttgtcc gggtccgcga cggcccgcat ccgcgccggg acctcgtcct
     9601 cgaccggctc cccctgcggg tcggcggccg ggatccgcag ccacagcgcg gccgccgaac
     9661 cgtccacggc gtagtcgatc cgcccctcct ccagcgccac gtccacgaag acgccgagga
     9721 acttcccgtg caccgcggcg cggtgctccg ggtccgggaa gacccagctg ctcaccgggt
     9781 cggtgcggaa ggactcgtcg agcagccggg ccaccgcgtc ccggtccgac tgatccgcct
     9841 gacgtatctc cagcgccact ggtcacaccc ttcactcacg tgtcaacaac cttgagcgat
     9901 cctagagttg gcgcggacat gcggtaaggc ccgttccggc accatgcggt accggaacgg
     9961 gcctcgggcc ccccttacgt ctcacctcgt gcggcgcgtg tcacctcgtg cggcgcgtca
    10021 cgaactccgc cagtgccagc agcccgcccg ccgcccccag gtccggcacg gcccgggaca
    10081 gctgctggac cgcccgcccc atccggtccg cggcctcggc ctgcgcccag tcccgcccgc
    10141 cggcccggtc caccgcgtcg gccgccctgc gtacgtcgtc cccggtcatg gggccggcgt
    10201 acagcgcggc cagctccttg cccgccgcgg tgcccgaggt gagggcggcc acgaccggga
    10261 gggacttctt gcgggcgatc aggtcggccc cggccggctt gccggtgtgc cccgggtccc
    10321 cccagatgcc gatcaggtca tcgatcagct ggaaggccag tccggcctcc cgcccgaacg
    10381 cgtccatggc gtcgacctcc tcgagcccgg cccccgcgta caaggctccc agcgcgcacg
    10441 cgcagcccag gagcgccccg gtcttggcgg tggccatggc caggcactcg tcgagcgaga
    10501 cctccgggcg ctgctcgaag gcgcagtccg cctgctggcc cgcgcacagc tcgatgatgc
    10561 aggccgcgag ccgggccgag gccgccgccg cggccggatg cggatcctcc gcgagcagcc
    10621 gcagcgcgag cgccatcatc gcgtcgcccg tgatgatggc gtccggcgtc ccgaagacgg
    10681 tccaggccgt ggcccggccg cgccgccgga cgtccttgtc gatgatgtcg tcgtgcagca
    10741 gcgtgaagtt gtgcgccagc tccacggcgg ccgccgcctt cacggcctcg tcggccggcc
    10801 cggcatccgg accgcgcagg gcctgcgccg cggccagcac cagggccggc cggatggcct
    10861 tccccgcgcc gcccgcggcc gggctgccgt cctcgtgctc ccagccgaag tggtacatcg
    10921 ccacccgccg catcgagccc ggcaggctct cgagggtacg gcgcagctgc gggtcgaccg
    10981 cttgtctcgt ccggtccagg agggctgcgg cgtcctggcc ctcaccggtc gcgatggcgt
    11041 tcacggcggt cagcgccagc ggccgatctc gacgttctcc agcacgccga gcgcgtccgg
    11101 caccagcacc gcggccgaga agtaggcggt gaccaggtac gagatgatcg cctgctcgct
    11161 gatgcccatg aaacggaccg acaggctcgg ctcgatctcg tccgggatgc ccggctggtg
    11221 gagcccgatc acgccctgct cgtcctcgcc ggtgcgcatg cacaggatgg acgtggtgcg
    11281 ggcatcgctg atcgggatct tgttgctcgg gaagatcggc accccgcgcc aggccggcac
    11341 ccggttgccg ccgacgtcca ccgactcggg gtagatcccg cgcttgttgc actcacggcc
    11401 gaaggcggcg atcgccttgg ggtgcgccag gaacagcttg gagccgcgcc gcatgctgag
    11461 cagctggtcc atgtcgtcgg ggctgggtgc gccgtcgtgc ggctggatgc gctggtcgta
    11521 gtcggcgttg tggagcaggc cgaagttgcg attgttgagc atctcgtgct cctggcgctc
    11581 gcgcagcgcc tcgaccgtga gccgcaactg ctgctcggtc tggttcatcg ggtggttgta
    11641 gaggtcggcg acgcggctgt ggacccgcag gaccgtttgt gcaatggaga gctcgtactc
    11701 gcgcggccgg gcctcgtagt cgacgaaggt gccggggagg acggcctcgc cctcgtggcc
    11761 ggcggagagc tcgatcgcgg cctcgccgta cttgttggtc tgccggtcgg gccggctccg
    11821 tacgccctcc acgtgcgcgc gcagcgattc gacccggtcg gcgaggagct ggaagtcctg
    11881 ccgggacagg gtgagggcgg tgccggaggt ggcggcgcgg gcggtgtact cccaaatcga
    11941 ttcttcatcg acgagggagt cgtcgccgaa gtacgcgccg tcggcgacgg tccgcaggac
    12001 ggcgtcctcg ccgtaggggc cggggccgat ctggtcgatg cggccgtggg cgagcaggaa
    12061 gacctcgtcg gcggggctgc cgaaggaggt gagctcctgt ccggcctcga agtcgatctg
    12121 ccggcagcgc tgggcgagtt cgccgaggac gtcgaggtcc tcgtagtcgc gcagcagcgg
    12181 gagctcaccg agctcggccg ggatcacctg gacctgggtg ccggtcttga tgaactccac
    12241 gacgccgttg ccgaccgagt agctcagcct gcggttgacg cggtacgtgc cgccctgcac
    12301 cgacacccac gggagcatct tcaggagcca ccgcgaggtg atctcctgca tctgcggcgc
    12361 ggacttggtc gtggttgcca agttccgtgc ggccgtggtc ccgagactgc gctgcggtgt
    12421 ctgggcctcg gactcggaac ctgcctggac cgacatgtct ttccctttcg atcactccat
    12481 ggatctgcgg gtgcagcttg tcagcacgga acgtggtcgg accattacac aaaagggtgg
    12541 gactactccg tccgggtgcg gggcaccctt tggggccacc tccttcccca cgagcctccc
    12601 cagccccacg cgacccatca atttcggcca tgcgcgaccc tcccgccgct ctaacttgca
    12661 taggagatgc aagtttccct acggtggccc catgcggctg acccgattca ccgacctggc
    12721 actgcgcgtc ctgatgcgcc tggccatcga ggaaacggac ctccccacca cccgtgacgt
    12781 ggcggcgacc atggaggtcc cctacacgca cacggccaaa gtggtcgcca gactgcagca
    12841 cctcggcctg gtcgaggcgc ggcgcggccg cggcggcggg ctcgccctga cctccgccgg
    12901 acgggccgcc ccggtcggct cggtggtgcg cgagctggag ggcgaggggg acgtcgtgga
    12961 ctgcgaaggc accaccccct gcccgctgcg cggggcctgc gtcctgcgcg gcgccctgcg
    13021 ccgtgcccag gaggccttct acgccgcgct ggacccgctg acggtgaacg acctggtggc
    13081 gtccccgacc gggccgctcc tgctgggcat ttcgagcagg gccccgaccg gggcgggcag
    13141 cagcccctga ccctcggccc gatgggccga tggccgatta ccgccgtcgg accggaccgg
    13201 tccacaccgt tccggcgcac gtccgaacag aagtccgcat cacggcggtc cttctgcgat
    13261 caaaaatatg catcttagat gcaaattcaa tcgatcacgc acacagcccc acagccccat
    13321 cacgcgagga gttccccatg ctgtccgaga cgtcgagcgc caccgtacga gccaccctgc
    13381 ccgccgtcgg agcggccatc ggcgagatag ccgagctctt ctacaccaag ctcttcgcgg
    13441 cccacccggc actgatccgc gacctcttca accgggggaa ccagaacgcc ggcctccaga
    13501 agcaggccct cgccggctcc gtcgccgcct tcgcgaccca cctcctcgcc cacccggaca
    13561 cgcggcccga cgtgatgctg aaccgcatcg cccacaagca cgccagcctc ggtgtgaccc
    13621 gcgagcagta cgcggtcgtc caccggcacc tgttcgaggc gatcgccgag gtcctcggcg
    13681 aggccgtcac ccccgaggta gcccgggcct gggacgaggt ctactggctg atggcgaacg
    13741 ccctgatcgc cctggaggag cgtctctacg ccgagcagca ggtcgtcgcc ggtgacgtgt
    13801 ggcgcaagtg gaccgtcacc gagcgggtgg cggagacggc ggactgcacc accttccgga
    13861 tcgctcccgc ggacggcgcc ccggcccccg cccaccggcc cggccagtac gtctcggtcc
    13921 aggtcgaact gccggacggc gcccgccaga tccgccagta cagcctcatc acctcccccg
    13981 gctccacgat ccgggcgatc accgtcaagc gggtccacgg cccggccgcc gcgggcccgg
    14041 acggcgaggt ctcccaccac ctgcacgccc gggtccgtac cggcgacacc ctgcgggtct
    14101 cggcccccta cggcgacctg gtcctggccg actcggccgc cccggtcctg ctcgcctcgg
    14161 ccggcatcgg ctgcaccccg atgctgtcga tgctggagca cctggccgac accgggcaca
    14221 ccgccccggt gaccgtgctg cacgcggacc gctcccccgc cgaccacccg ctgcggggcg
    14281 accaccgggc gctgacgcac aagctggccg acgcctcggc ccggttctgg tacgaggagg
    14341 cggcggagcc gggcgacggc cagggccgca tggacctctc ggccgtcgcc ctggcgccgg
    14401 gcacccgggc ctacctgtgc ggaccgctcc ccttcatgcg ggccgtgcgc gagcagctga
    14461 tcgccaaggg gctgccggcc gccgacatcc actacgaggt cttcggcccg gacctgtggc
    14521 tcgcatcggt ctgacacctg gccggatcgg ctcgctcgcc gtacgaaggc actagcgcgg
    14581 aggggtcgcc tccactaaac cggagggtga cgagacgagc acagagggtg tccgtcgcgc
    14641 accgcaacga aggaggcggc catggccgca cccatgtccg cggaccgctt catcaacgca
    14701 ctgcggaacg agggtctgac cgtcgtcgaa gtcggcgcct ggcggaccca caaccgcaac
    14761 cacaagggcc cctgggggcc ggttcacggg gtgatgatcc accacaccgt cacccgcggc
    14821 accgcccaca ccgtcgagct ctgccgcgag ggccacagcg ccctccccgg ccccctgtgc
    14881 cacggcgtga tcgccaagga cggccgcgtc cacctggtcg gctacggccg cgccaaccac
    14941 gcgggcgccg gtgactccga cgtcctcgcg gcggtcatcg cggagaagcg gctcccgccg
    15001 gacaacgaga cggacaccga cggcaaccgc cacttctacg gcttcgagtg cgagaacctc
    15061 ggcgacggcg aggacccctg gcccgccgtc cagctcgacg ccatcgcccg cgccgcggcg
    15121 gccctgtgcc gggtccacca ctggacggcc cgctcggtga tcggccaccg cgaatggcag
    15181 ccgggcaagg tcgaccccag gggcttcacg atggacgcca tgcgcgcccg catcggcgag
    15241 cgcctgaagt agcccgtccc ccacaatccg tcccccacca gggacaatga cccggtgacc
    15301 catcccgaac tgctgccgcg cccgccgtcc gcgctcgtcg aggcggcgga cgacaggttc
    15361 gaacggtacg gcgtgcggct gctgctgaag cgcgacgacc tcgtgcatcc gcagctgccc
    15421 ggcaacaagt ggcgcaagct cgcgcccaat ctccgggccg ccctcgcggg cggccacgat
    15481 cagctgctca ccttcggcgg ggcgtactcg aaccacctgc gcgccaccgc cgccgccggg
    15541 cggctgctcg ggctgcggac ggtcggcgtc gtgcgcgggg acgagctcgc cgggcggccc
    15601 ctgaacgact ccctcgcccg gtgcgccgca gacggtatgc ggctgcactt cgtctcccgg
    15661 tccgagtacc gccgcaaggc cgagccggac cggctggcac ggctggtgga cgcggcgggc
    15721 gcgcgcggtg cgtacgtcgt ccccgagggc ggcagcaacg cgctcgccct ggccggctgc
    15781 gccgagctcg gccgggaact gcgcggcgcc gccgatgtgg tggcggtggc ctgcggcacc
    15841 ggcggcaccc tggcgggcct cgcggccggg ctgggccccg ggcagcgggc gctcggtgtt
    15901 ccggtcctgg cgggcggctt cctggccgcg gagatacgtt ccctccaggc ggccgccttc
    15961 gggggtccgg ccggcgactg gaccctggcc gaggacttcc accacggcgg ctacgcccgg
    16021 gtcccggccg cgctggaggc cttcgccgcc gacttcgcct cccgccacgg cctgccggtc
    16081 gagcggatct acgtggccaa gctgctctgg gccctgaccg aactcaccgc ctccggcgcc
    16141 ttcccgcccg gtacgaccct cgccgccgtg gtcacgggcc ggccgtagcc gcgcccgacg
    16201 ccccggcgcc ccggccccga cgccggcctc agccctcctc gcggtaggcc gcggcctcct
    16261 ccaggtccag ccggcgcagc agcgcccgca gcatctcgtc gtcgatccgg cgctggtccc
    16321 gcagcgtcac gaagacctcc cgctcggcgg cgatcatctc ccgggcgagg cgccggtaga
    16381 tgtcgtccgc cgactccccc gtctccgggt tgacctcgcc cagccgctcc cacaccgcat
    16441 tgcgccgccg ctccagcacc gtgcgcagcc ggtccgccag cggcggcggc agcgtgctgc
    16501 tctccggttc ctccagcagc tccgccagcc gttcctccgc cgcccgcgag gcctcgctct
    16561 gcgcctgcgc ctcggccagg gtctcggcct gcacgtcctt cggcggcagg ttcagcgccc
    16621 ggatcagcgg cggcagcgtc agcccctgca ccaccagcgt cccgatgacc gtggtgaagg
    16681 tcaggaagag gatcaggttc cggtgcggca ccgacatggg cacggagaag gcgatggcca
    16741 gcgagaccac gccgcgcatc ccggcccatc ccacgatcac cggagccttc cagtcggtgt
    16801 cgctctcccg cgcccggatc cgctccgaca gccagcgcgg cacgaaggtc gccgggaaca
    16861 cccacaggaa ccgggccacc accaccgcga ggaacacggc gaccgcgtac gtggccgcgt
    16921 gcatgccgtc gtactccccg agcccgccca ggaccaccgg cagctggagc ccgatcagcg
    16981 cgaagaccac cgactccagc acgaaggcga ccaccctcca caccgcctcc tcctggaggc
    17041 gggtggcgaa gtcgacctgc cagttgcggt ggccgaggta cagcgcgacg acgaccacgg
    17101 ccagcacccc ggaggcgtgc acccgctccg cggccgcgta cgccacgaag gggatcagca
    17161 gcgagagggt gttctggagc agcggctcct tcagccgcgt gcgcagctgg tggatgggga
    17221 ccatcagcag caggccgacg ccgataccgc cgaccgaggc cagcaggaac tccgcgatgc
    17281 cgcccgccca gccggcgctc accccgacgg ccgcggccag cgccaccttg tacgcggtga
    17341 tcgcggtggc gtcgttgacc agggactcgc cctgcaggat ggtcgtgatg cggttcggca
    17401 gccgcagctt gcgggcgatc gcggtggccg cgacggcgtc cggcggggcg atcaccgcgc
    17461 ccagcaccag cgccaccggc atggtcagcc ccggcaccag caggtacgcc gcgtatccga
    17521 cggcgagcgt cgcgaagagc acgtagccca ccgagagcat cgcaatgggc cggatgttcg
    17581 cgcgcaggtc caggtacgag ctgtccacgg cggccgtgta cagcagcggc gggagcagca
    17641 gcggcagcac gatgtgcggg tcgagcgtgt acgccggcac cccgggcacg tacccggcca
    17701 gcaggccgaa gacgaccagc agcagcggcg cgggcaccgg ggtccgacgg gccagtccgg
    17761 cgacggccgc gctgccggcg atcagcgcca ccagcggcaa tacctccatc gaagatccac
    17821 ctcaatcgtc ggccgctcgc cccgaacgcg cgggcttgac cgaggagatc ctcatgactc
    17881 gcacggcggg aacgtattct gtacgagatc aagctccggt caaagcgtga cgcatcgaca
    17941 ctccgctgca tcgcagctcc ggcccgtgcg cgcggttcgc cccgagactg aaggccgggg
    18001 ttccggtaca aggagaatgc gatgagcgag tgcacccacg ttgccgaact gccgcgtccc
    18061 gaaccggtgc cctcccacga cacctgctcc gagtgcctgg cgctcggcag ccaccccgtg
    18121 cagctgcgga tgtgcctggg gtgcgggcac gtggcctgct gtgattcctc gccccaccgg
    18181 cacgccaccg cgcaccaccg ggagaccggc catccggtga tgcggagctt cgaaccgggc
    18241 gagacctggc gctggtgttt tgtcgacggt tcgatcgtct gaggcggggt agttcaaccc
    18301 tccgccggtt cccctgattt gggccccgca gacccctagc cactgtgcgt acccatgggc
    18361 ttaccatcag tcactggctc gcaggcgggg tgctcggagc gggtaccaag aggggtgccg
    18421 cgacacgatc gcccggatcg cgatagcgtc accggcgaac agagctcgta ccaccttgga
    18481 ggtgagggtg tcccagatcg caggcgagcc cgggactcag gacttcgtgg aagtccggct
    18541 gcccgctgcg ggtgcctacc tgtcggtgct gcggacggcc acggccggtc tcgcggcacg
    18601 tttggacttc accctcgacg agatcgagga cctccgcatc gcggtggacg aggcctgcgc
    18661 gatcctgctc cagcaggccg tgccgggctc cgtcctcagt tgcgtgttcc ggctgatcga
    18721 cgattcgctg gaagtgacgg tctcggcgcc caccaccgac ggacgggcgc ccgagcgtga
    18781 cacgttcgcg tggaccgtgc tgtcggcact ggccggcaag gtcgaggcca cggtcgagga
    18841 gaaccggacg gtgagcatca gcctctacaa acagcgcggc gcgggaccag gcccggcgtg
    18901 agcggcgggg agatcccggt acggggcggg gatcggcccc gggtacgaca cgaggtcgac
    18961 ggcggcatcc cggagcaaca gcacgcccga ccgcacccgg ctgacgcgga tgcggaagac
    19021 ggctttttgg actcggcgga gcgacgggcg ggccctatga gcgagaacca gcaggaacag
    19081 ccacaaccat cccggccgac cgaggccacg gccccggcgg cgccggtggt tccggcagtg
    19141 ccggcggcgc cggtgttccc ggtgaccccg gccctgccgg atccgcgcga ccgcagtggc
    19201 gcgcgggcgc tgttcatcga actgcgggca ctgcccgacg gttcggtgga gaaggcggag
    19261 ctgcgcaacc ggctggtacg gatgcacctg ccgctggtgg aacacctggc gcggcgcttc
    19321 cgcaaccgcg gtgagccgct ggacgacctg acgcaggtcg cgaccatcgg cctcatcaag
    19381 tcggtggacc ggttcgaccc ggaccgcggg gtcgagttct ccacgtacgc cacgcccacg
    19441 gtggtcggcg agatcaagcg ccacttccgc gacaagggct gggcggtccg ggtgccgcgt
    19501 cgcctgcagg agctgcggct ctcgctgacg acggccacgg ccgaactgtc ccagcagcac
    19561 ggccgctccc cgacggtgca cgaactggcc gagcggctgg ggatctccga ggaggaggtg
    19621 ctggaggggc tggaatcggc caatgcctac agcacgctct cgctcgacgt cccggacacc
    19681 gacgacgagt cgccggcggt cgcggacacc ctgggcgcgg aggacgaggc cctggagggc
    19741 gtcgagtacc gcgagtccct caagccgctg ctggagggcc tgcccccgcg ggagaagcgg
    19801 atcctgctgc ttcgcttctt cggcaacatg acccagtcgc agatcgccca ggaggtcggc
    19861 atctcccaga tgcacgtctc ccggctgctg gcccgcaccc tggcccagct ccgcgacaag
    19921 ctcctcgtcg aggagtaacg ggcagcgggc agcggggctc ggcggcgggg aagaaccgga
    19981 cgaccggcta tcgggcctgt tccccgggcc cgataccgag agcctcggtc gccgtcgggt
    20041 tcaccaggag cgccacgacg gccaccgcgg ccagggccag cgccacggcg gcggcgatca
    20101 tcgcgccgcc ggtgctgtac agggtccagg ccaccggcag cgccatcagc tgggtgatca
    20161 gcgccgggcc gcggctccag cgccggccca ggcgcagccc ccgggcagcg atcagcggca
    20221 gtgcggcgag tgcgagcagg gtgatcccgc ccgtctcggc ctgctgcggg gagtcggggt
    20281 cgccggcgat ccccacgaac agcatgtaga gcccgaggcc ggccagcgcc aggccctcca
    20341 gggcggtgag cgcggcggcc gcggtcagcc ggccgggcag cgcggcgggc ggggccgcgg
    20401 acgggtcggc ggcgggggcg ggggcgttcg cgggctgctt cttactcacc ccagcagggt
    20461 agcggcgcgg cccccgggcc cggaggggac gggcagtacg gtcggcatcg gagggggtgg
    20521 gtagtctggc gctcatgcgt gcacttctcg tggccaaccc agcagcgacg accaccagtg
    20581 cgcgcacgcg cgacgtcctg acccacgccc tggccagcga gatgaagctg gaggcggtca
    20641 ccaccgagta ccgcgggcac gcccgggacc tgggacggaa ggcggcgcac gaggggctcg
    20701 acctcgtcgt cgccctgggc ggcgacggca cggtcaacga ggtggtgaac gggctcctgc
    20761 acaacgggcc cgatccggag cgcctccccc ggctggcggt ggttcccggc gggtccacca
    20821 atgtgttcgc ccgcgcgctg gggctgccca acgatgcggt cgaggcgacc ggagccctcc
    20881 tggacgcgct gcgggagcag cgcgagcgga cggtgggtct gggcctggcg gccggcaccc
    20941 cgggcaccga ggacgagtcg gtcccggccc gctggttcac cttctgcgcg ggcttcggct
    21001 tcgacgccgg cgtggtgggc cgggtggagc agcagcgcga gcgcggcaag cgt
//
