LOCUS       NZ_CP020555            22217 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. Sge12 chromosome, complete genome.
ACCESSION   NZ_CP020555
VERSION     NZ_CP020555.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Sge12
  ORGANISM  Streptomyces sp. Sge12
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7983613)
  AUTHORS   Tao,M., Xu,J., Xu,M., Liu,K., Zhao,Z. and Peng,Q.
  TITLE     Genome sequence of Streptomyces sp. Sge12, producing unknown
            compounds against rice blast disease
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7983613)
  AUTHORS   Tao,M., Xu,J., Xu,M., Liu,K., Zhao,Z. and Peng,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, Huashan Road 1954, Shanghai 200030,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: RS_HGAP Assembly v. 3; BWA v. 0.7.10; Bowtie v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 85.0x
            Sequencing Technology :: Illumina HiSeq 4000; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:12:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,312
            CDSs (total)                      :: 7,216
            Genes (coding)                    :: 7,106
            CDSs (with protein)               :: 7,106
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 32 of 111
            Pseudo Genes (incomplete)         :: 91 of 111
            Pseudo Genes (internal stop)      :: 8 of 111
            Pseudo Genes (multiple problems)  :: 18 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:35:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1816985
            Orig. end                         :: 1839202
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020555.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22217
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22217
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22217
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12217](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12217
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            134..883
                     /gene="cobM"
                     /locus_tag="B6R96_RS08060"
                     /old_locus_tag="B6R96_08065"
     CDS             134..883
                     /EC_number="2.1.1.133"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0046026 - precorrin-4
                     C11-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047282.1"
                     /locus_tag="B6R96_RS08060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08065"
                     /product="precorrin-4 C(11)-methyltransferase"
                     /protein_id="WP_081522105.1"
                     /sec_met_domain="TP_methylase (E-value: 3.2e-42, bitscore:
                     143.6, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVYFIGAGPGAADLITVRGARTLAAAPVCLYAGSLVPRELLAEC
                     PADARLVDTSQLNLDEIVAEYVRAHAAGQDVARLHSGDPSIFSAVAEQMRRLDAAGIPY
                     EVVPGVPAFAAAAAALKRELTVPTVGQTVILTRIAQQATPMPPGEDLATLGRSGALLVL
                     HLATRYVDRVVDELLPHYGAQCPVAVVAMASRPDELILRGTLSDIAAQVKAHGLVRTAV
                     IVVGRTLGAEQFRDSHLYSAERDRHVC"
     gene            873..1634
                     /locus_tag="B6R96_RS08065"
                     /old_locus_tag="B6R96_08070"
     CDS             873..1634
                     /EC_number="1.3.1.106"
                     /GO_function="GO:0016994 - precorrin-6A reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267287.1"
                     /locus_tag="B6R96_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08070"
                     /product="cobalt-precorrin-6A reductase"
                     /protein_id="WP_081522106.1"
                     /transl_table=11
                     /translation="MSAEPTPRPAHHVLILGGTTEARQLAEALASDPSVHVTTSLAGRV
                     ASPALPPGDTRIGGFGGIAGLAAWIVAHDVTRVVDATHPFAEQMSFHASEAEALTGVPL
                     LALRRPGWTPQPADDWTFVDSLADAAALLPGFGNRAFLTTGRMGLHTFAHLTDTWFLVR
                     SVDPPAAPVPPRLEVLLARGPFTLEDERELLARHRIDVLLTKDSGGSATAPKLTAAREA
                     GIPVLVVRRPPVPQGVPEADSVDAVLDWLGA"
     gene            complement(1706..3205)
                     /locus_tag="B6R96_RS08070"
                     /old_locus_tag="B6R96_08075"
     CDS             complement(1706..3205)
                     /EC_number="2.1.1.130"
                     /GO_function="GO:0030788 - precorrin-2
                     C20-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267285.1"
                     /locus_tag="B6R96_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08075"
                     /product="precorrin-2 C(20)-methyltransferase"
                     /protein_id="WP_030389757.1"
                     /sec_met_domain="TP_methylase (E-value: 2.8e-50, bitscore:
                     169.9, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAEAKGRLYGVGLGPGDPSLMTLRAVEVIAEADVVAYHSARHG
                     RSIARSIAAKHLRADHVEEPLVYPVTTETTDHPGGYQGAMEEFYEAAAARLAAHLDAGR
                     TVAVLAEGDPLFYSSYMHMHKRLADRYETEVIPGVTSVSAAAARLGTPLVEGEEVLTIL
                     PGTLSEEELTARLAATDSAVVMKLGRTFPAVRGAMENSGRLAEARYVERATMAGERTGR
                     LADTDPESVPYFAVAVVPSRIGNPGSVPSGPGEVVVVGTGPAGPLWLTPQTRRALADAE
                     VLVGYTTYLDRVPVRPGQIRHGSDNKVESERAEFALDLARRGQRVAVVSGGDPGVFAMA
                     TAVLEVAGQAEYKDVPVRVLPGVTAANAAAAAAGAPLGHDYATVSLSDRLKPWEVIAER
                     LRAAAAADLVLALYNPGSRSRTWQVAQARELLLELRSPETPVVVARDVGGPEQTVRIVT
                     LAELEPSEVDMRTILLIGSSQTQVTERADGSRITWTPRRYP"
     gene            complement(3202..3849)
                     /locus_tag="B6R96_RS08075"
                     /old_locus_tag="B6R96_08080"
     CDS             complement(3202..3849)
                     /EC_number="5.4.99.61"
                     /GO_function="GO:0016993 - precorrin-8X methylmutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267284.1"
                     /locus_tag="B6R96_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08080"
                     /product="precorrin-8X methylmutase"
                     /protein_id="WP_237291375.1"
                     /transl_table=11
                     /translation="MSEYTVFEYEKDGAAIYRQSFATIRAEADLSGLPDTVAQVAVRMI
                     HACGMTDLPQDLGYTPEVVLRARAALEAGAPILCDVQMVASGVTRKRLPAGNDVICTLS
                     DPAVPELAARMGTTRSAAALEVWRDRGLLEGSVIAVGNAPTALFRLLEMIEEGAPRPAA
                     VIGVPVGFIGAAESKDALAAHPSGLDHLIVRGRRGGSAMAAAAVNAIASVAE"
     gene            complement(3846..5138)
                     /gene="cobG"
                     /locus_tag="B6R96_RS08080"
                     /old_locus_tag="B6R96_08085"
     CDS             complement(3846..5138)
                     /EC_number="1.14.13.83"
                     /GO_function="GO:0016709 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, NAD(P)H as one donor, and incorporation
                     of one atom of oxygen [Evidence IEA]"
                     /GO_process="GO:0019250 - aerobic cobalamin biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="cobG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004938317.1"
                     /locus_tag="B6R96_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08085"
                     /product="precorrin-3B synthase"
                     /protein_id="WP_237291376.1"
                     /transl_table=11
                     /translation="MPQPPSAASRDEPVIRERGDACPGALRLHAADDGFLARVRLPGGL
                     LTGPQAAALALAADRFGDGHLELTSRGNVQLRGLADGCGGALAELLDGAGLLPAPSHER
                     VRNIVATPLSGLEGPDRPDALAWAMDFDRMLCASPWAAALSGRFLFAFDDGRGDVASLG
                     PDVTVLGRPAGRALVRLGRAADAVELAGPDAPRAALSAARYFLGAAAEAGTQAWRVSEL
                     PVEHALRTVEFVRRLDAAGIAATAVGAVDWPYAPAPRPPGAGTRARATLCVLPPLGRVD
                     SAQWRVLAQVAQEGGGELRVTPWRSVILPSVKGDAPARIEDAGLVVAPDSPWETVTACT
                     GRPGCAKSLADVRADARAVVDRARGPLPVHWSGCERRCGHPRGTAWVDLVATGTGYRIT
                     APGRPVRHDVRPPELAAALADARTDPDVVKK"
     regulatory      5621..5704
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            5760..9377
                     /gene="cobN"
                     /locus_tag="B6R96_RS08085"
                     /old_locus_tag="B6R96_08090"
     CDS             5760..9377
                     /EC_number="6.6.1.2"
                     /GO_function="GO:0051116 - cobaltochelatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobN"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1263: cobaltochelatase subunit CobN"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743402.1"
                     /locus_tag="B6R96_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08090"
                     /product="cobaltochelatase subunit CobN"
                     /protein_id="WP_081522108.1"
                     /transl_table=11
                     /translation="MILLLSTSDTDLLSARAANTADGPVPYRFANPSRLPLDDLPGLLD
                     GADLVVVRLLGGLRAWQDGLDLLLAPGQTRPVVVLTGEQAPDAQLMEASTVPIGIAAEA
                     HGYLAHGGPANLEQLARFLSDTVLLTGHGFEPPAASPTWGPLERTPGTTAGPRIAVLYY
                     RAHQMSGNTSFVHALCDAIEAHDAQALPLYVSSLRTPEPELIAALESADAVVTTVLAAG
                     GTKPATASAGGDDESWDAGALAGLGVPILQALCLTGSRAAWEENDEGLSPLDAATQVAV
                     PEFDGRLITVPFSFKEIDEDGLPAYVADPERAARVAGIAVRHARLRHIDRRDKKVALVL
                     SAYPTKHSRIGNAVGLDTPASAVELLRTLIAGGYDFGPTEDIPGLVSGDGDELIRALIE
                     AGGHDQDWLTEEQLARNPVRIPAADYKRWFAELPAELRDSVTEHWGEAPGNMFVDRSAN
                     PEGDIVLAALRRGNLLILIQPPRGFGENPIAIYHDPDLPPSHHYLAAYRWIQARAEDGG
                     FGADAMIHLGKHGNLEWLPGKNAGLSAACAPDAALGDLPLIYPFLVNDPGEGTQAKRRV
                     HATLVDHLVPPMARAESYGDIARLEQHLDEYAQISAMDPAKLPAIRAQIWTLIQAAKLD
                     HDLGLEERPDDDGFDDFLLHVDGWLCEVKDAQIRDGLHVLGGAPTGEARVNLVLAILRA
                     RQIWGGTTALPGLREALGLDESKATRTSADEVEAQARALVQAMEDANWSLDAVSSVASG
                     HSADVAAVLSFAAREVVPRLAGTTDEIAHVVAALDGRFIPAGPSGSPLRGLVNVLPTGR
                     NFYSVDPKAVPSRLAWETGQALAESLLTRYRTDNGEWPASVGLSLWGTSAMRTSGDDVA
                     EALSLLGIRPVWDEASRRVTGLEPIPLAELGRPRIDVTLRISGFFRDAFPHVIGLLDDA
                     VRLAASLDEPASDNYIRAHAQADLAEHGDERRATTRIFGSRPGTYGAGILQLIDSRDWR
                     TDADLAEVYTVWGGYAYGRGLEGRPARDEMETAYKRITVAAKNTDTREHDIADSDDYFQ
                     YHGGMVATVRALRGTAPEAYIGDSTRPETVKTRTLVEETSRVFRARVVNPKWIEAMRRH
                     GYKGAFELAATVDYLFGYDATTGVVADWMYDKLTETYVLDPTNRAFLEEANPWALHGIA
                     ERLLEAESRGMWEKPDPQILESLRQVYLDTEGNLEGESE"
     gene            complement(9485..9706)
                     /locus_tag="B6R96_RS08090"
                     /old_locus_tag="B6R96_08095"
     CDS             complement(9485..9706)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008411999.1"
                     /locus_tag="B6R96_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08095"
                     /product="hypothetical protein"
                     /protein_id="WP_030390548.1"
                     /transl_table=11
                     /translation="MAIDLDKVLDKAWADKPLAEVLAAPVAALKGVSDEDGKLLHEAFG
                     VKTVADFGQLKYVRWAQALVALNQTVKA"
     gene            10001..12217
                     /locus_tag="B6R96_RS08095"
                     /old_locus_tag="B6R96_08100"
     CDS             10001..12217
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743400.1"
                     /locus_tag="B6R96_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08100"
                     /product="Geosmin synthase"
                     /protein_id="WP_081522109.1"
                     /sec_met_domain="T1TS (E-value: 2.3e-76, bitscore: 256.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFQLPDFYVPYPARLNPHLEDARTHTKQWARDFGMLEGSGVW
                     EESDLDSHDYALLCSYTHPDCDRDALALVTDWYVWVFFFDDHFLEMYKRSQDRNGAKEY
                     LDRLAAFMPMDLSGGFPEATNPVEAGLADLWARTVPAMSADWRERFSLSTKNLLNESMW
                     ELANINIGRVANPLEYIEMRRKVGGAPWSAGLIEYVSAEVPARVAHSRALGVLRDSFSD
                     AVHIRNDIFSYQREVADEGELSNAILVLETFLGCTTQEAAEASNDLLTSRLQQFEQTAL
                     VELPQLFADHALDPAEIAAVLAYTKGLQDWQSGGHEWHMVSSRYMNKEARPTAPATLPF
                     LPSGLGTTALDLRSVFTKRSMELRHRSFTHVPFESTGPSVIPEIYMPHRLSLSPHLAHA
                     REESVAWARRMGLLDPQPGDPGSAIWTEERLRGFDFAVCSAGIDPDATPEQLVLNASWL
                     TWGTYGDDYYPVVFARCRNLPAAKATTARLLSMITVDHAEQPEPVTAMERSLGDLWVRT
                     SAGMSVEQRTEFRATLVSMLESWLWEVDNQIQNRIPDPVDYAEMRRHTFGSHLTMYLCR
                     LGHRGRSIPEEIYASGTIRSLENAVADAACLINDIYSYQKEVEVEGEVHNYILVTQNFF
                     DIDYPQALHICHELMTRRTEEFEHIVATQLPVLYDDWKLDAGAREALDAYVGELQDWHA
                     GILNWHQKIRRYRPQDLHPQPDLLATGILGNGFGMSAARISLPA"
     gene            complement(12266..13510)
                     /locus_tag="B6R96_RS08100"
                     /old_locus_tag="B6R96_08105"
     CDS             complement(12266..13510)
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743398.1"
                     /locus_tag="B6R96_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08105"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_081522110.1"
                     /transl_table=11
                     /translation="MVDIREVPESDIDRALELAYLVFHDRPEKEVREKHHALLASCDRI
                     GAYDGAALVGFMAAHDFRLSVPGADLPCPGLTFVCVAPTHRRRGVLTGLMERMLRRTAA
                     AAGPIAALWASEAAIYGRFGYGSATTGATIEIDSSRPLALRIAPDRRPLRLLDPEEALA
                     VIGPFHEAARAGRAGRPTRSAQRWREEWLAEQDEEDEELSPPRIIVLGDPGEPIAGYVL
                     YRTKAEDDAAAVRVPGRVRVDELEADSPAVAAALWECVASLDLTGKVSAWGRPVDDPLL
                     HFAADRDQVRVTAQFPALWVRLVDVRAALTARSWAAPVEVVLEVQDVRLPANAGRFRLK
                     AGPHGATYEHDHPDSGAAADLALDVRELAACYLGGTRVEELVAAGLVREHTPGAAAALD
                     AALRTPVMPHTSDEF"
     gene            13699..14241
                     /locus_tag="B6R96_RS08105"
                     /old_locus_tag="B6R96_08110"
     CDS             13699..14241
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677098.1"
                     /locus_tag="B6R96_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08110"
                     /product="GNAT family protein"
                     /protein_id="WP_030390551.1"
                     /transl_table=11
                     /translation="MIEGERVALRALRAQDAEHHLRWRNDPEVVRWATAGDPCFGPVTR
                     EALTMFFERMLMLPPRESAVFTVETVADRRVIGMVDYRDLDPWAGTATLGITIGEREFW
                     GRGHGSEALRLLVDHLFGSFPLTRLQLDTWSGNERAVRAFTRLGFREEGRRRAAVLLAG
                     ERYDEVLFGMLREEWRP"
     gene            14416..14883
                     /locus_tag="B6R96_RS08110"
                     /old_locus_tag="B6R96_08115"
     CDS             14416..14883
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718707.1"
                     /locus_tag="B6R96_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08115"
                     /product="OsmC family protein"
                     /protein_id="WP_030390552.1"
                     /transl_table=11
                     /translation="MARLHSYATRVTWTGNLGTGTSHYRAYSRAHEVAAGELPAILGSS
                     DPAFRGDASRWNPEQLLLAALSQCHMLSYLHFCTVNGVVVTSYVDEATGTMATAGDSGH
                     FTEVVVHPRITVGEESMVAAAIDLHKEAHRACFIANSVNFPVRHEPTVTVG"
     gene            complement(14942..16270)
                     /locus_tag="B6R96_RS08115"
                     /old_locus_tag="B6R96_08120"
     CDS             complement(14942..16270)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237826.1"
                     /locus_tag="B6R96_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08120"
                     /product="YncE family protein"
                     /protein_id="WP_237291377.1"
                     /transl_table=11
                     /translation="MRTRRTARTPRTLRPARTPRTLRTLGLLAAAALLTALTPLPAAVG
                     AGPAPGSGPGSGPGGGLREVLFVGNNWEGTADVLASTGDLAKVGRIDVVPDKAERLREI
                     YLNPVKLAFFLGIRESAGEGHDQFVDDMYTTPDGSVVVVSRPSFADVVSIDVTSGRINW
                     RFPVSGFRSDHMAVSPDGTRVAVSASTSNTVHVLDITTGRQVGSFGTGDKPHENTFTRD
                     GRFLWNSSIGEVNTALDAPWLDWTKGDRKITVVDAQTFRTVRVIDMRERLDAFGRRDLS
                     DAVRPVSFSPDESKLYFQVSFFGGFLEYDVPSDRITRLKNLPANPATSPDRTTWVNDSR
                     HHGMSMSPDGSKLCIAGTMDDYATVVDRATLAEGPLVPAAKPYWATIDGDGSSCVISES
                     GADQVTAIDFATGAKRVSVPVGDHPQRIRLGHVPAGWTGPGTR"
     gene            complement(16426..17577)
                     /locus_tag="B6R96_RS08120"
                     /old_locus_tag="B6R96_08125"
     CDS             complement(16426..17577)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037137.1"
                     /locus_tag="B6R96_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08125"
                     /product="XdhC/CoxI family protein"
                     /protein_id="WP_053177586.1"
                     /transl_table=11
                     /translation="MLDIAEELNRWVEQGRDFAVATVVAVGGSAPRQPGAALAVDSEGT
                     AIGSVSGGCVEGAVYELCLQALEDGETVQERFGYSDDDAFAVGLTCGGIIDILVTPVRV
                     GSPAREVFAAGLAAAARGEAAAVARIAQGPAELMGRAVFVRTEGAHQGGFGGHPELDRT
                     VAEEARAMLDAGRTGVLEIGADGRLCGEPLQVLVESSVPPPRMIVFGAIDFASALVRIG
                     KFLGYRVTVCDARPVFATKTRFPEADEIVVDWPHRYLETTDVDGRTVLCVLTHDAKFDV
                     PLLELALKLPVAYVGAMGSRRTHEDRNKRLREVGVTELELARLRSPIGLDLGARSPEET
                     ALSIAAEIVANRRGGSGAALTGAHIPIHPDITKTVIDRIGSVA"
     gene            17567..17782
                     /locus_tag="B6R96_RS08125"
                     /old_locus_tag="B6R96_08130"
     CDS             17567..17782
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B6R96_RS08125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B6R96_08130"
                     /product="hypothetical protein"
                     /protein_id="WP_159396304.1"
                     /transl_table=11
                     /translation="MSSMGASSVRFGSSIGYGERSVHDDRVDRIGSTRSIGRSRSTTGA
                     VDRAEQVEQIDQVEQVDQAGLIGGPT"
     gene            complement(17793..19256)
                     /locus_tag="B6R96_RS08130"
                     /old_locus_tag="B6R96_08135"
     CDS             complement(17793..19256)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125408.1"
                     /locus_tag="B6R96_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08135"
                     /product="NCS2 family permease"
                     /protein_id="WP_030390555.1"
                     /transl_table=11
                     /translation="MTQSSVEPKTAAEEAGDGSQPPAGRSWLDRYFHITHRGSNIGNEV
                     RGGITTFMAMAYILLLNPLLLSGKDVAGTSMAASAIITATAFAAAVTTLLMGFVGKVPL
                     ALAAGLSVSGVLASQVAPQMTWPQAMGMCVVYGVVICLLVVTGLREMIMNAIPLALKHA
                     ITMGIGLFVALIGFVKAGFVGRGPEFGPPVQLGAVGELSGWPVMLFCITLIAIFMLQAR
                     KVPGAILIGIVGGTVLAAILNAIVDIDPKAWKSGPPELSGSAISKPDFSLFGDVSFGGW
                     GDVGYMTVGMIVFTLVLAGFFDAMATIIGVGTEAKLADDKGRMPGLSKALFIDGAGGAI
                     GGISGGSGQTVFVESATGVGEGARTGLASVVTGLFFAACLFFTPITQIVPGEVASAALV
                     VIGAMMMQNARHVDWSDSATSIPVFLTVVIMPYTYSITAGVAAGVISYVAIKIAQGKAR
                     EIGGFMWALTGIFLVFFALNPIEHWLGVG"
     gene            complement(19578..21980)
                     /gene="pucD"
                     /locus_tag="B6R96_RS08135"
                     /old_locus_tag="B6R96_08140"
     CDS             complement(19578..21980)
                     /EC_number="1.17.1.4"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pucD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267276.1"
                     /locus_tag="B6R96_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_08140"
                     /product="xanthine dehydrogenase subunit D"
                     /protein_id="WP_030390556.1"
                     /transl_table=11
                     /translation="MAQNTRTVPAGTPTNVTQKHNKGGIGESILRPDGTLKVTGEFAYS
                     SDMWHEDMLWGQTLRSTVAHAEIVSIDISEALAMPGVYSVLTYDDLPAEMKNYGLEIQD
                     TPVLANGRVRHHGEPVALVAADHPETARRAAAKIKIDYRELPLVTDEASALAPDAPLIH
                     EGRDDHHIGHVPHPNIVHRQPIIRGNVEEARKRADVIVEGEYTFGMQDQAFLGPESGLA
                     VPSEDGGVELYVATQWLHSDLQQIAPVLGLPPEKVRMTLSGVGGAFGGREDISMQIHAC
                     LLALATNKPVKIVYNRFESFFGHVHRHPAKLYYEHGATKDGKLTHMKCKIVLDGGAYAS
                     ASPAVVGNASSLSVGPYVLEDVDIEAIALYTNNPPCGAMRGFGAVQACFAYEAQMDKLA
                     AKLGMDPVEFRQLNAMEMGTVMPTGQVVDAPAPVAELLRRVKARPMPPERQWESAGENA
                     DVRALPGGLSNTTHGEGVVRGVGYAVGIKNVGFSEGFDDYSTARVRLEVINGEPVAMVH
                     TAMAEVGQGGITVHTQIARTELGVTQVTIHPADTQVGSAGSTSASRQTYMTGGAVKNTC
                     EAVREALLEIGRRKNGSYHPAWATAELLLEGGKVVTDGGEVLADIADILEDEAIDLELE
                     FRHAPTEAFDLRTGQGNGHVQYTFAAHRAVVEVDTELGLVKVVELATAQDVGKALNMLS
                     VVGQIQGGTTQGLGVAIMEEIIVDPKTAKVRNPSFTDYLIPTILDTPTIPVDVLELADP
                     KAPYGLRGMGEAPTLSSTPAVIAAIRQATGLEINKTPIRPEALTGTL"
ORIGIN
        1 tgaagctcgc cgtcgcgcac gccgtgccgg tcggcggttt cacgggctgg cggcaggcca
       61 tgccggtcac ccagtggtcg gtgacgaagt cggacggacc gaccgcgggg tcggccgagg
      121 agagggatcg aacatgaccg tgtacttcat cggtgcgggc ccgggcgccg ccgacctgat
      181 cacggtgcgc ggtgcccgga ccctggccgc cgcccccgtc tgcctgtacg cgggcagcct
      241 cgtaccgcgc gagctgctgg ccgagtgccc cgcggacgcg cggctcgtcg acacctcgca
      301 gctcaacctc gacgagatcg tcgccgagta cgtacgggcc cacgcggccg gccaggacgt
      361 ggcacggctg cactccggcg acccgtcgat cttcagcgcg gtcgcggagc agatgcgccg
      421 actcgacgcg gccggcatcc cctacgaggt cgtcccgggc gtgccggcct tcgccgcggc
      481 ggccgccgcc ctcaagcggg agctgaccgt ccccaccgtc gggcagacgg tgatcctgac
      541 ccggatcgcc cagcaggcca ccccgatgcc gcccggcgag gacctggcca cactgggccg
      601 cagcggcgcg ctgctggtgc tgcacctggc cacccgctac gtggaccgcg tcgtcgacga
      661 gctgctgccg cactacgggg cccagtgccc ggtggcggtc gtggcgatgg ccagccgccc
      721 cgacgaactg atcctgcgcg gcaccctgtc cgacatcgcc gcccaggtga aggcgcacgg
      781 cctggtgcgc accgcggtca tcgtggtggg ccgcacgctc ggcgcggagc agttccgcga
      841 cagccatctg tactcggccg aacgcgaccg gcatgtctgc tgaaccgact ccccgcccgg
      901 cgcaccacgt cctgatcctg ggcgggacga cggaggccag gcagctcgcg gaggcgctgg
      961 catccgaccc ctcggtccat gtgaccacct cgctcgcggg ccgggtcgcc tcgccggcgc
     1021 tcccgcccgg cgacacccgg atcggcggct tcggcggcat cgcgggcctc gcagcctgga
     1081 tcgtcgccca cgacgtcacc cgggtcgtcg acgccaccca cccgttcgcg gagcagatga
     1141 gtttccacgc ctccgaggcg gaggcgctta cgggcgtccc gctgctggcg ctgcggcgcc
     1201 ccggctggac accgcagccc gccgacgact ggaccttcgt ggactcgctc gccgacgcgg
     1261 ccgcgctgct gcccggcttc ggcaaccgcg ccttcctcac caccggccgg atgggcctgc
     1321 acaccttcgc gcacctcacc gacacctggt tcctggtgcg ttcggtggac cccccggcgg
     1381 cgccggtgcc gccgcgcctg gaagtcctgc tcgcccgggg cccgttcacc ctggaggacg
     1441 agcgggagct gctcgcccgg caccggatcg acgtcctgct gacgaaggac agcggcggct
     1501 cggccaccgc ccccaagctc accgcggccc gcgaggccgg catcccggtc ctcgtggtgc
     1561 gccgcccgcc ggtcccgcag ggcgtaccgg aggccgactc ggtcgacgcc gtcctggact
     1621 ggctcggcgc ctagaccgtc gaaagggcgg tgccggtacc ggcaccgccc tgtcgacttc
     1681 gaccctcggg tcacatcacg tcacatcacg ggtagcggcg cggcgtccag gtgatcctcg
     1741 acccgtcggc ccgctcggtg acctgcgtct gcgaggagcc gatcagcagg atcgtgcgca
     1801 tgtccacctc ggacggctcc agttcggcga gcgtgacgat gcgtacggtc tgctccgggc
     1861 cgcccacgtc gcgcgcgacg accaccgggg tctcgggcga ccgcagctcc agcagcagct
     1921 cgcgggcctg ggccacctgc caggtccggc tgcgcgagcc ggggttgtag agggccagta
     1981 ccaggtcggc cgcggcggcc gcgcgcagcc gctccgcgat gacctcccag ggcttgagcc
     2041 ggtccgagag ggagaccgtg gcgtagtcgt ggccgagcgg cgcgcccgcc gcggcggcgg
     2101 ccgcgttggc cgcggtcacc cccggcagga cccgtaccgg cacgtccttg tactccgcct
     2161 gcccggccac ctccaggacc gccgtggcca tggcgaagac accggggtcg ccaccggaga
     2221 ccacggccac ccgctgcccg cgccgggcga ggtcgagggc gaactcggcg cgctccgact
     2281 ccaccttgtt gtcggagccg tggcggatct ggcccggcct gacgggcacc cggtccaggt
     2341 aggtggtgta gccgaccagc acctcggcgt cggccagcgc gcgccgggtc tgcggggtga
     2401 gccacagcgg gcccgccggg ccggtgccga cgacgacgac ctcgcccggg ccggacggca
     2461 cgctgcccgg gttgccgatg cggctgggga ccacggcgac ggcgaagtac gggacggact
     2521 ccgggtccgt gtcggcgagg cggccggtgc gctcgccggc catggtggcg cgctcgacgt
     2581 accgggcctc ggcgagccgg ccgctgttct ccatcgcgcc gcgcacggcg gggaaggtcc
     2641 ggccgagctt catcacgacc gccgagtcgg tggcggcgag gcgggcggtg agctcctcct
     2701 cggacagggt gccgggcagg atggtcagca cctcctcgcc ctccacgagc ggggtgccga
     2761 gccgggcggc ggcggcgctc accgaggtga ctccggggat gacctcggtc tcgtaccggt
     2821 ccgcgagccg cttgtgcatg tgcatgtacg agctgtagaa gagcggatcg ccctcggcga
     2881 gcacggcgac ggtccggccg gcgtccaggt gggcggcgag gcgggcggct gcggcctcgt
     2941 agaactcctc catcgcgccc tggtagccgc cggggtggtc ggtggtctcg gtggtgaccg
     3001 ggtagaccag cggttcctcg acgtggtcgg cgcgcaggtg cttcgcggcg atcgagcggg
     3061 cgatggaacg gccgtggcgg gcactgtggt aggccaccac atcggcctcg gcgatcacct
     3121 cgacggcgcg cagggtcatc agcgacgggt cgccggggcc gagcccgacc ccgtacagcc
     3181 gccccttggc ctcggcggcg ctcattcggc cacgctcgca atggcgttga ccgcggcggc
     3241 ggccatggcg ctgccgccgc gccggccgcg cacgatcagg tggtcgagcc ccgaggggtg
     3301 cgcggcgagg gcgtccttgg actcggcggc gccgatgaag ccgaccggga ccccgatgac
     3361 ggcggcgggg cgcggggcgc cctcctcgat catctccagc agccggaaca gggcggtcgg
     3421 cgcgttgccc acggcgatca ccgagccctc cagcaggccg cggtcgcgcc agacctccag
     3481 ggcggcggcg ctgcgcgtgg tgcccatccg cgcggcgagc tccggcacgg ccgggtcgga
     3541 gagcgtgcag atcacgtcgt tgccggcggg cagccgcttg cgggtgacac cgctggcgac
     3601 catctgtacg tcgcacagga tcggcgcgcc cgcctccagc gccgcacggg cgcgcagcac
     3661 gacctcgggg gtgtacccga ggtcctgcgg gaggtcggtc attccgcagg cgtggatcat
     3721 gcgcaccgcg acctgggcga ccgtgtcggg cagtccggag aggtccgcct cggcgcggat
     3781 cgtggcaaag gactggcggt agatggccgc gccgtccttc tcgtactcaa acacggtgta
     3841 ctcgctcatt tcttcactac gtcggggtcg gtgcgggcgt ccgcgagtgc cgcggcaagt
     3901 tcggggggcc gtacgtcgtg gcgtacgggg cggccggggg cggtgatccg gtatccggtg
     3961 ccggtggcga ccaggtccac ccaggcggtg ccgcgcggat ggccgcagcg gcgctcgcag
     4021 ccggaccagt gcacgggcag cgggccgcgg gcccggtcga cgacggcccg cgcgtcggcg
     4081 cgcacgtccg ccagggattt cgcgcaaccg ggccgcccgg tgcaggcggt gacggtctcc
     4141 caggggctgt cgggggcaac gaccagcccg gcgtcctcga tgcgggcggg cgcgtccccc
     4201 ttcaccgagg gcaggatgac gctgcgccac ggggtgacgc gcagctcgcc gcccccctcc
     4261 tgcgcgacct gcgccaggac ccgccactgg gcggagtcga cccggccgag cgggggcagc
     4321 acgcacagcg tggcgcgggc acgggtaccc gcgcccgggg gccggggcgc cggcgcgtac
     4381 ggccagtcca cggcgccgac ggccgtcgcg gcgatcccgg cggcgtcgag gcgccggacg
     4441 aactcgacgg ttctcagggc gtgttcgaca ggaagttcgg acacccgcca ggcctgggtg
     4501 cccgcctcgg cggcggcgcc gaggaagtac cgggcggccg acagggccgc ccggggtgcg
     4561 tccggcccgg ccagctccac ggcgtcggcg gcccggccga gccggacgag cgcccggccc
     4621 gcggggcggc cgaggacggt cacgtccggg ccgagcgagg ccacgtcccc gcgcccgtcg
     4681 tcgaaggcga acaggaaccg cccggacagc gcggccgccc aggggctcgc gcacagcatc
     4741 cggtcgaagt ccatggccca ggccagcgca tcgggccggt cgggcccctc cagcccggac
     4801 agcggggtcg ccacgatgtt ccgtacccgc tcgtggctcg gcgcggggag caggccggct
     4861 ccgtcgagca gctccgcgag cgcgccgccg cacccgtcgg ccagtccgcg cagctgtacg
     4921 ttgccgcgcg aggtcagttc caggtgcccg tcgccgaacc ggtcggcggc gagcgccagc
     4981 gccgcggcct gcggcccggt gagcagcccg cccgggagcc ggacgcgcgc gaggaaaccg
     5041 tcgtccgccg cgtgcagccg cagcgcgccg gggcaggcgt caccgcgctc ccgtatgacg
     5101 ggttcgtccc gcgatgcggc ggaagggggc tggggcatgg ccgcgagcat acccacgatc
     5161 ccacccccgg gacctgtgtc catcaccacc ccgaccagca ccatcgaccg atccgccccc
     5221 acccacccca ccccaccggc acccagggcc cggagccccc cactcccagc cccgcccacg
     5281 ctcgacgccc gacccatcca gcctcgccgg cgtttgaggt gcggggcccg gggcagagcc
     5341 ccgcacttcc agcctcgccg gcgtttgagg cgcggggccc ggggcagagc cccggcagcg
     5401 gcgccgcacc cggccacgcc agctccgccc cgcccatccc atcccgaacc gccccgctac
     5461 cccacccggt cggcgcccag acgcagagcc ccggcaacgg cgccgcaccc ggccacgccg
     5521 gccccgcccc caccccgccc gcccccacgg gaccactccg cccctaagat gaccttccgg
     5581 cggaccacac ggcccgccgt cgccgaggac ggcgacatgg gaggaagccc ggtgcgattc
     5641 cggcgcggtc ccgccactgt gaaccccgcg gagcgatccc gcgcccgggg tgagtcagga
     5701 actcccgctg tcctcacact gcccggggcg cggaaacccc gaggaaggcc tgccgccgca
     5761 tgatcctgct gctgtcgacg tccgacaccg atctgctcag cgcccgcgca gcgaacacgg
     5821 cggacggccc cgtcccgtac cggttcgcga acccctcccg tctccccctc gacgacctgc
     5881 ccggcctcct cgacggggcc gacctggtcg tcgtacgcct cctcggcggc ctccgcgcct
     5941 ggcaggacgg cctcgacctg ctcctcgccc ccggccagac ccgtccggtc gtggtcctga
     6001 ccggcgaaca ggccccggac gcgcagctca tggaggcctc cacggtcccc atcggcatcg
     6061 cggccgaggc ccacggctac ctcgcccacg gcggcccggc caacctggag cagctggccc
     6121 ggttcctctc cgacaccgtc ctgctgaccg gccacggctt cgagcctccg gccgcctccc
     6181 ccacctgggg cccgctggag cgtacgcccg ggaccaccgc ggggccgcgg atcgcggtgc
     6241 tctactaccg cgcccaccag atgagcggca acacctcctt cgtgcacgcc ctgtgcgacg
     6301 cgatcgaggc ccacgacgcc caggcgctgc ccctgtacgt gtcctccctg cgcacccccg
     6361 agccggagct gatcgcggcc ctggagtcgg ccgacgcggt cgtcaccacc gtcctcgcgg
     6421 ccggcggcac caagcccgcc accgcctcgg cgggcggcga cgacgagtcc tgggacgcgg
     6481 gcgcgctcgc cggcctcggt gtgccgatcc tgcaggccct gtgcctgacc ggctcgcgcg
     6541 ccgcctggga ggagaacgac gagggcctgt ccccgctgga cgccgccacg caggtcgcgg
     6601 tgcccgagtt cgacggccgc ctgatcaccg tcccgttctc cttcaaggag atcgacgagg
     6661 acggcctgcc cgcctacgtg gccgaccccg agcgggccgc ccgggtcgcg gggatcgccg
     6721 tacgccacgc ccgcctgcgg cacatcgacc gccgcgacaa gaaggtcgcg ctggtcctct
     6781 ccgcgtatcc gacgaagcac tcgcgcatcg gcaatgcggt cggcctggac accccggcca
     6841 gcgccgtgga gctgctgcgc accctcatcg ccggcggcta cgacttcggg ccgaccgagg
     6901 acatcccggg tctggtctcg ggcgacggcg acgagctgat ccgcgccctg atcgaggccg
     6961 gcggccacga ccaggactgg ctgaccgagg agcagctggc ccgcaacccg gtccggatcc
     7021 cggccgccga ctacaagcgg tggttcgccg aactcccggc cgagctgcgc gacagcgtca
     7081 ccgagcactg gggcgaggcc ccgggcaaca tgttcgtgga ccgctcggcg aacccggagg
     7141 gcgacatcgt cctcgccgcc ctgcgccgcg ggaacctcct catcctcatc cagccgccgc
     7201 gcggtttcgg cgagaacccg atcgcgatct accacgaccc ggacctgccg ccgtcgcacc
     7261 actacctggc cgcgtaccgc tggatccagg cgcgcgcgga ggacggcggc ttcggcgccg
     7321 acgcgatgat ccacctgggc aagcacggca acctcgaatg gctccccggc aagaacgccg
     7381 gcctgtccgc cgcctgcgcg cccgacgcgg ccctcggcga cctgcccctc atctacccgt
     7441 tcctggtcaa cgacccgggc gagggcaccc aggccaagcg ccgcgtgcac gccaccctgg
     7501 tcgaccacct ggtgccgccg atggcgcgcg cggagtcgta cggcgacatc gcgcgcctgg
     7561 agcagcacct ggacgagtac gcccagatct ccgccatgga cccggcgaag ctgccggcca
     7621 tccgcgccca gatctggacc ctgatccagg cggcgaagct cgaccacgac ctcggtctgg
     7681 aggagcgtcc ggacgacgac ggcttcgacg acttcctgct gcacgtcgac ggctggctgt
     7741 gcgaggtcaa ggacgcccag atccgcgacg gcctgcacgt cctgggcggc gcgccgaccg
     7801 gtgaggcccg ggtcaacctg gtcctggcga tcctgcgcgc ccgtcagatc tggggcggta
     7861 cgacggccct cccgggcctg cgcgaggcgc tcggcctgga cgagtccaag gcaacccgca
     7921 cctcggcgga cgaggtcgag gcccaggccc gcgccctggt ccaggcgatg gaggacgcga
     7981 actggtccct cgatgccgtg tcctcggtgg cgtcgggcca ctcggcggac gtcgcggcgg
     8041 tgctgtcctt cgcggcccgc gaggtggtcc cgcggctggc cggcaccacg gacgagatcg
     8101 cccacgtggt cgccgcactg gacggccgct tcatcccggc gggcccgtcc ggctctccgc
     8161 tgcgcggcct ggtcaacgtc ctcccgacgg gccgcaactt ctactcggtc gaccccaagg
     8221 ccgtcccctc ccgcctcgcg tgggagacgg gccaggccct ggccgagtcc ctcctcaccc
     8281 gctaccgcac ggacaacggc gagtggccgg cctcggtcgg cctgtccctg tggggcacga
     8341 gcgcgatgcg cacctcgggc gacgacgtgg cggaagccct ctccctcctc ggcatccgcc
     8401 cggtctggga cgaggcctcg cggcgcgtca ccggcctgga gccgatcccg ctcgcggagc
     8461 tcggccgtcc ccgcatcgat gtcaccctcc gcatctcggg cttcttccgc gacgcgttcc
     8521 cgcacgtcat cggcctgctg gacgacgcgg tacgcctggc cgcgtccctc gacgagcccg
     8581 cctcggacaa ctacatccgg gcccacgccc aggcggacct ggccgagcac ggcgacgaac
     8641 gccgcgcgac gacccgtatc ttcggctcgc gcccgggcac gtacggggcc ggcatcctcc
     8701 agctgatcga ctcccgcgac tggcgtacgg acgccgacct cgcggaggtc tacacggtgt
     8761 ggggcggcta cgcgtacggc cgcggcctcg aagggcgccc cgcccgggac gagatggaga
     8821 cggcctacaa gcgcatcacg gtcgcggcga agaacacgga cacgcgcgag cacgacatcg
     8881 cggactcgga cgactacttc cagtaccacg gcggcatggt ggccacggtc cgcgccctgc
     8941 gcggcaccgc tccggaggcc tacatcggcg actccacccg cccggaaacg gtcaagaccc
     9001 gcaccctggt cgaggagacc agccgcgtct tccgcgcccg cgtcgtgaac cccaagtgga
     9061 tcgaggcgat gcgccgccac ggctacaagg gcgccttcga gctcgcggcg acggtggact
     9121 acctcttcgg ctacgacgcc acgacgggcg tggtcgcgga ctggatgtac gacaagctca
     9181 ccgagacgta cgtcctggac ccgacgaacc gcgccttcct ggaggaggcc aacccgtggg
     9241 ccctgcacgg catcgcggag cgcctgctgg aggccgagtc ccgcggcatg tgggagaagc
     9301 cggacccgca gatcctcgaa tccctccgcc aggtctacct ggacacggaa ggcaacctgg
     9361 agggcgagtc ggagtagccc tccgcaccac acaggccgtc cccctcaccc tgccgaaggg
     9421 tgagggggac ggcctttttc attcaggccc acgaaccccg aacacgcgga cccggcacta
     9481 cgtgctacgc cttgacggtc tggttcagcg cgacgagcgc ctgggcccag cggacgtact
     9541 tcagctgccc gaagtcggcg acggtcttga ccccgaacgc ctcgtgcagc agcttgccgt
     9601 cctcgtcact gacacccttg agcgcggcaa caggagccgc aagcacctcg gcgagcggct
     9661 tgtcggccca cgccttgtcg agcaccttgt ccagatcgat cgccatgaac gtccctctcg
     9721 gaatcccgaa acgaatatcg gggcaaacct aacccaatcc gacaatcacc ccacgctccg
     9781 acaccccggg tccgttgccg atccgccgtg cgggggctac cccaagacac acccccctag
     9841 cccgcggcag ggccccatgt cggggaacgg gtggttcgtc acctgatgaa gtgaactcac
     9901 ccttgtccca cgcgcaccag gggtagggca ctgctgatct cgtgcggggg gaccggggcg
     9961 accgggctcc cgtacccatg gacgaaaggc cgagcccgcc gtgacgcagc cgtttcaact
    10021 gccggatttc tatgtgccct atccggcacg actgaacccc cacctggagg acgcacggac
    10081 ccacaccaag cagtgggccc gcgacttcgg gatgctggag ggttccggcg tctgggagga
    10141 gagcgacctc gactcgcacg actacgcact gctctgctcg tacacccacc ccgactgcga
    10201 ccgcgacgcg ctggcgctgg tcaccgactg gtacgtgtgg gtgttcttct tcgacgacca
    10261 cttcctggag atgtacaagc gctcgcagga ccgcaacggc gccaaggagt acctcgaccg
    10321 gctcgccgcg ttcatgccga tggacctgtc cggcgggttc cccgaggcca ccaacccggt
    10381 ggaggcggga ctcgcggacc tgtgggcgcg caccgtgccc gcgatgtccg ccgactggcg
    10441 ggaacggttc tccttgtcga cgaagaacct cctcaacgag tccatgtggg agctcgccaa
    10501 catcaacatc gggcgcgtcg cgaacccgct cgaatacatc gagatgcgcc gcaaggtggg
    10561 cggcgccccc tggtcggccg gcctgatcga gtacgtgtcc gccgaggtgc ccgcgcgcgt
    10621 cgcgcactcg cgcgcactcg gcgtgctgcg cgactccttc tccgacgccg tgcacatcag
    10681 gaacgacatc ttctcctacc agcgcgaggt cgccgacgag ggcgaactct ccaacgccat
    10741 cctggtgttg gagaccttcc tcggctgcac cacccaggag gcagccgagg cctccaacga
    10801 cctgctcacc tcccgcctcc agcagttcga gcagaccgcg ctcgtcgagc tcccccagct
    10861 cttcgccgac cacgcgctgg acccggcgga gatcgcggcc gtgctcgcct acaccaaggg
    10921 cctgcaggac tggcagtccg gcggccacga gtggcacatg gtctccagcc gctacatgaa
    10981 caaggaggcc cggcccaccg cccccgccac cctgcccttc ctgccgtcgg ggctcggcac
    11041 caccgcgctc gacctgcggt ccgtgttcac gaagcgctcg atggagctgc gccaccgctc
    11101 cttcacccac gtgcccttcg agagcaccgg cccctccgtc atccccgaga tctacatgcc
    11161 gcaccggctc agcctcagcc cgcacctggc gcacgcgcgc gaggaatccg tggcctgggc
    11221 ccggcggatg ggactgctgg acccgcagcc cggcgacccc ggctcggcca tctggaccga
    11281 ggagcggttg cgcggcttcg acttcgccgt ctgctcggcc gggatcgacc ccgacgccac
    11341 accggagcag ctggtgctca acgcctcctg gctgacctgg ggcacgtacg gcgacgacta
    11401 ctacccggtg gtcttcgccc ggtgcaggaa ccttccggcg gccaaggcga ccaccgcccg
    11461 cctgctctcc atgatcacgg tcgaccacgc cgaacagccc gagccggtga ccgcgatgga
    11521 gcgctcgctc ggcgacctgt gggtgcgcac cagcgccggc atgtccgtcg agcagcgcac
    11581 cgaattccgg gcgaccctgg tgagcatgct ggagagctgg ctgtgggagg tggacaacca
    11641 gatccagaac cgcatcccgg acccggtgga ctacgcggag atgcgccgcc acaccttcgg
    11701 cagccatctc acgatgtacc tgtgccgcct ggggcaccgg ggccggagca tccccgagga
    11761 gatctacgcc tccgggacca tccgttcact ggagaacgcg gtcgcggacg ccgcctgcct
    11821 gatcaatgac atctactcct accagaagga ggtggaggtc gagggcgagg tccacaacta
    11881 catcctggtc acacagaact tcttcgacat cgactacccg caggccctgc acatctgcca
    11941 tgagctgatg acccggcgga ccgaggagtt cgagcacatc gtggccacgc agctgccggt
    12001 gctctacgac gactggaagc tcgacgccgg ggcccgggag gcgctggacg cgtacgtggg
    12061 cgagttgcag gactggcacg ccggcatcct caactggcac cagaagatcc gccgttaccg
    12121 cccgcaggac ctgcatccgc agccggacct gctggccacc gggatcctgg gcaacggctt
    12181 cggcatgtcg gccgcccgga tctccctgcc cgcctgatcc cgatgccctg cggcgggggc
    12241 cccgcccccg cccccgccgt acgggtcaga actcgtcgct cgtgtgcggc attaccggcg
    12301 tacgcagggc cgcgtccagc gccgccgccg caccgggcgt gtgctcccgt accagaccgg
    12361 ccgcgacgag ctcctcgacc cgggtcccgc cgaggtagca cgcggccagt tcgcggacgt
    12421 ccagggccag gtcggcggcg gctccggagt ccgggtggtc gtgctcgtac gtcgccccgt
    12481 gcggccccgc cttgagccgg aaccgcccgg cgttggcggg cagccgtacg tcctgcacct
    12541 ccagcaccac ctccaccggc gcggcccagg accgcgccgt cagggcggcg cgtacgtcga
    12601 ccaggcgcac ccagagcgcc gggaactggg cggtgacccg cacctggtcc cggtccgcgg
    12661 cgaagtgcag cagcgggtcg tcgaccgggc ggccccacgc cgagaccttg ccggtgaggt
    12721 cgagggaggc cacgcactcc cacagcgcgg cggccaccgc cgggctgtcg gcctccagtt
    12781 cgtcgacccg gacccggccc ggcacgcgga cggccgcggc gtcgtcctcc gccttggtgc
    12841 ggtagagcac gtatccggcg atcggctcgc cggggtcccc gaggacgatg atccgcggcg
    12901 ggctcagctc ctcgtcctcc tcgtcctgtt cggccagcca ctcctcgcgc cagcgctgcg
    12961 cgctgcgggt gggccggccg gcccgcccgg cgcgggcggc ctcgtggaag gggccgatca
    13021 cggcgagggc ctcctcgggg tcgaggagcc gcagcggccg ccggtccggt gcgatgcgca
    13081 gggccagcgg gcggctggag tcgatctcga tggtggcgcc ggtggtggcg ctgccgtagc
    13141 cgaagcgacc gtagatggcg gcttcggagg cccagagggc ggcgatcgga ccggccgcgg
    13201 cggccgtccg gcgcagcatc cgctccatca gcccggtgag tacgccgcgc cggcggtggg
    13261 tgggggcgac gcagacgaag gtgagcccgg ggcagggcag gtccgccccc ggcaccgaga
    13321 gccggaagtc gtgcgcggcc atgaaaccga ccagggcggc gccgtcgtag gcgccgatcc
    13381 ggtcgcaact cgcgagcagc gcgtggtgtt tctcccggac ctccttctcg ggccggtcgt
    13441 ggaagaccag gtaggcgagc tccagagcac ggtcgatgtc ggactcgggt acctcgcgga
    13501 tgtccaccat gatcgcgaga ctaatcggtc atggaggact ggtcacccca taaaggtcga
    13561 ggttgcggct ttcggctgct ccggtggccg gccgccgagg cggggtacct cggcggctcc
    13621 gaaaacccgt cgccaccatg atcacctgtg ggtacggtgt gccctcggat gccacaggga
    13681 cggggagagg atcagggctt gatcgaggga gagcgcgtcg cgctgcgcgc actgcgcgcg
    13741 caggacgcgg agcaccacct gcgctggcgc aacgaccccg aggtggtccg ttgggcgacc
    13801 gccggggacc cgtgcttcgg cccggtcacc cgggaggcgc tgacgatgtt cttcgagcgg
    13861 atgctgatgc tcccgccccg ggagtcggcg gtgttcacgg tggagaccgt ggcggaccgc
    13921 cgggtgatcg gcatggtcga ctaccgcgac ctggatccct gggccggaac ggccacgctc
    13981 gggatcacca tcggcgagcg ggagttctgg ggccgggggc acggctccga agcgttgcgg
    14041 ctgctggtcg accacctctt cggcagcttc cccctcaccc ggctccagct cgacacctgg
    14101 agcgggaacg agcgggcggt ccgggcgttc acccggctcg gcttccggga ggagggccgg
    14161 cggcgggcgg ccgtgctgct ggcgggcgag cggtacgacg aggtgctgtt cgggatgctc
    14221 cgggaggagt ggcggccctg acccggccgc ggtgcgtccg ccgggcgccc gccgggcgcc
    14281 cggcggacga gcggccgacg cggccgtcgc gtcggccgta ccatccaggt cggcgcccgg
    14341 caccgcccga cgtcgccgcc acaccccggg cacgcgtgtc gcccggcccc gcacccgaga
    14401 gacggagtag ccgccatggc ccgactgcac tcctacgcca cccgcgtcac ctggaccgga
    14461 aacctcggca ccggcaccag ccactaccgc gcctactccc gggcgcacga ggtggccgcc
    14521 ggagagctgc cggcgatcct cggcagctcg gacccggcgt tccgcggcga tgcctcccgc
    14581 tggaaccccg agcaactgct gctcgccgcg ctgtcccagt gccacatgct ctcctacctg
    14641 cacttctgca cggtcaacgg cgtggtggtc acctcgtacg tcgacgaggc gaccgggacg
    14701 atggccacgg ccggggacag cgggcacttc acggaggtcg tggtgcaccc ccggatcacc
    14761 gtcggcgagg agtcgatggt ggccgcggcg atcgacctgc acaaggaggc ccaccgggcc
    14821 tgcttcatcg ccaactcggt caacttcccc gtccggcacg agccgaccgt gacggtgggc
    14881 tgagccaccg ggccggcccg gtcgcgccgt ggtcccgcaa cgggaccagg acgcccgctc
    14941 cctagcgggt gccgggaccg gtccagccgg ccgggacgtg gccgagccgg atgcgctggg
    15001 gatggtcgcc gacggggacg gagacccgct tggcgccggt ggcgaagtcg atggccgtga
    15061 cctggtcggc gccgctctcg gagatcacgc agctgctgcc gtcgccgtcg atcgtggccc
    15121 agtacggctt ggcggcgggc acgagcgggc cttcggcgag ggtggcccgg tccacgacgg
    15181 tcgcgtagtc gtccatggtg cccgcgatgc agagcttcga cccgtcgggg ctcatggaca
    15241 tgccgtggtg gcgggagtcg ttgacccagg tggtccggtc ggggctggtg gcggggttcg
    15301 ccgggaggtt cttcaggcgg gtgatccggt cggagggcac gtcgtactcc aggaagccgc
    15361 cgaagaagga cacctggaag tagagcttcg actcgtcggg gctgaaggac accgggcgga
    15421 cggcgtcgga caggtcgcgg cggccgaagg cgtccagccg ctcgcgcatg tcgatcaccc
    15481 ggaccgtgcg gaaggtctgc gcgtcgacca cggtgatctt gcggtcgccc ttcgtccagt
    15541 ccagccaggg cgcgtccagg gccgtgttga cctcgccgat ggagctgttc cacagaaagc
    15601 ggccgtcgcg ggtgaaggtg ttctcgtgcg gcttgtcgcc ggtgccgaag gagccgacct
    15661 ggcggccggt ggtgatgtcc aggacgtgca cggtgttgga ggtggaggcc gacacggcga
    15721 cgcgggtccc gtccggggag acggccatgt ggtcggaccg gaaaccggac accggaaagc
    15781 gccagttgat ccggccggag gtcacgtcga tggacacgac gtcggcgaag ctggggcggg
    15841 agacgacgac gacggagccg tcgggggtgg tgtacatgtc gtcgacgaac tggtcgtgcc
    15901 cctcgccggc gctctcccgg atgccgagga agaaggcgag cttcacgggg ttgaggtaga
    15961 tctcgcgcag ccgttccgcc ttgtcgggga ccacgtcgat ccggccgacc ttggcgaggt
    16021 cgccggtgga ggcgagcacg tcggcggtcc cctcccagtt gttccccacg aagagcacct
    16081 cgcgcagccc gccgccgggg ccgcttccgg gaccggagcc cggagcaggg cccgctccga
    16141 ccgccgccgg gagcggcgtc aaggcggtga ggagggcggc cgcggccagc aggcccaggg
    16201 tccgcagagt gcgcggggtg cgcgcgggtc gcagggtgcg cggggtacgc gcggttcgcc
    16261 gggtgcgcac ggttcgtaac atccgctcaa ctccgctacg ggggaaggga tggagagggt
    16321 gcctactctt accggccggt aagatagggg ggacgccaaa agggcgcaac ccccacgggt
    16381 tgcgcccttt cctcaccttc ggtgaccggg cggccggtca ggcagtcaag ccacggatcc
    16441 gatccggtcg atcaccgtct tcgtgatgtc cgggtggatc gggatgtgcg cgccggtcag
    16501 ggccgcgccg ctgccgccgc ggcggttcgc gacgatctcg gcggcgatgg acagcgcggt
    16561 ctcctccggg gagcgggcgc cgaggtccag gccgatcggg gagcgcagcc gggccagttc
    16621 gagctcggtc acgccgacct cgcgcagccg cttgttgcgg tcctcgtggg tgcggcgcga
    16681 gcccatggcg ccgacgtagg cgacgggcag cttgagcgcc agttcgagga gcgggacgtc
    16741 gaacttggcg tcgtgggtga gcacgcacag gacggtccgg ccgtccacgt cggtggtctc
    16801 caggtagcgg tggggccagt cgacgacgat ctcgtccgcc tcggggaagc gggtcttcgt
    16861 cgcgaagacg ggccgggcgt cgcacaccgt cacgcggtag ccgaggaact tgccgatccg
    16921 cacgagggcg gaggcgaagt cgatggcacc gaagacgatc atccgcgggg gcgggacgct
    16981 ggactcgacc agtacctgga gcggctcacc gcagagccgg ccgtcggcgc cgatctccag
    17041 tacgccggtc cggccggcgt cgagcatggc gcgggcctcc tcggccacgg tgcggtccag
    17101 ctcggggtgt ccgccgaatc cgccctggtg ggcgccttcg gtacggacga acacggcgcg
    17161 gcccatgagc tcggccgggc cctgcgctat ccgggccacc gccgcggcct cgccgcgggc
    17221 cgcggcggcc aggccggccg cgaacacctc ccgggcgggt gagcccacgc ggaccggggt
    17281 gaccaggatg tcgatgattc cgccgcaggt caggcccacg gcgaaggcat cgtcgtcgct
    17341 gtacccgaag cgctcctgga cggtttcgcc gtcctccagc gcctggaggc acagctcgta
    17401 gaccgcgccc tccacgcatc cgccggagac cgagccgatg gccgtgccct cgctgtcgac
    17461 ggcgagggcg gcaccgggct gccggggcgc gctcccgccg accgccacga cggtggcgac
    17521 ggcgaagtca cgtccctgct cgacccaccg gttcagctct tcggcgatgt ccagcatggg
    17581 ggcctcctcg gtgaggttcg gttccagtat cggatacggg gagcgttcgg ttcacgacga
    17641 ccgggtcgac cggatcgggt cgacccggtc gatcgggcgg agcaggtcga ccacgggagc
    17701 agtcgaccgg gcggagcagg tcgagcagat cgaccaggtc gagcaggtcg atcaggccgg
    17761 tctcatcggt ggaccgacct gatcggtgcg ggtcagccga ccccgagcca gtgctcgatc
    17821 gggttcaggg cgaagaacac caggaagatc ccggtcagcg cccacatgaa gccgccgatc
    17881 tcccgggcct tgccctgagc gatcttgatg gccacgtacg agatgacacc ggcggcgacg
    17941 ccggccgtga tcgagtacgt gtacggcatg atcacgacgg tcaggaagac cgggatcgag
    18001 gtcgcactgt cggaccagtc cacgtggcgg gcgttctgca tcatcatcgc gccgatgacg
    18061 accagcgccg cggaggcgac ctcacccggg acgatctgcg tgatcggggt gaagaagagg
    18121 caggcggcga agaacaggcc ggtgacgacg gaggcgagac ccgtgcgggc accctcgccg
    18181 acgccggtcg cggactcgac gaagacggtc tgaccggagc cgcccgagat gccaccgatg
    18241 gcaccaccgg cgccgtcgat gaagagcgcc ttggacaggc ccggcatgcg gcccttgtcg
    18301 tcggccagct tggcctcggt gccgacaccg atgatggtgg ccatggcgtc gaagaagccg
    18361 gcgagcacca gggtgaagac gatcatgccg accgtcatgt agccgacgtc gccccagccg
    18421 ccgaaggaga cgtcgccgaa gagcgagaag tccggcttcg agatcgcgga gccgctgagc
    18481 tccggcgggc cgctcttcca ggccttcggg tcgatgtcga cgatggcgtt gaggatcgcg
    18541 gccaggacgg tgccgccgac gatgccgatc aggatggcgc cgggcacctt gcgggcctgg
    18601 agcatgaaga tggcgatcag ggtgatgcag aagagcatga cgggccagcc ggacagctca
    18661 ccgaccgcac cgagctggac ggggggaccg aactccggac ccctgcccac gaaaccggcc
    18721 ttgacgaagc cgatcagggc gacgaagagg ccgatgccca tggtgatcgc gtgcttgagc
    18781 gcgagaggga tcgcgttcat gatcatctcg cggaggccgg tgacgaccag gagacagatc
    18841 acgacgccgt agaccacaca catgcccatg gcctgcggcc aggtcatctg gggggccacc
    18901 tgcgaggcca gcacgccgga gacggagagg ccggcggcaa gggcgagcgg caccttgccg
    18961 acgaagccca tgagaagcgt ggtgacggcc gcggcgaacg cggtggcggt gatgatcgcc
    19021 gaggcggcca tcgacgtacc ggcgacgtcc ttgcccgaga ggagcagggg gttgagcaga
    19081 aggatgtacg ccatcgccat gaaggtcgtg ataccgccac gaacctcatt gccgatgttg
    19141 gagcctctgt gcgttatgtg aaagtaccgg tcgagccagg acctgccggc gggtggctga
    19201 gagccgtcgc cggcctcttc cgctgcggtc ttgggctcta ctgacgattg ggtcatggtg
    19261 cctaactccc aaggttcaaa ggggcacccg cttggagatt ggagatgcgg gatttgggat
    19321 gctgcgtttg gctgcacgac ccggggtgac ggcccgaggc gacgcgaatg tgcactgcgt
    19381 gtactgcggg tagtgcgggg gtgaccgctg gtactacggg ggttcttgca ggggtactgc
    19441 cgggtgaagg gaccgcgagc ggtgcggtgc ttcgttggtc ctccggacgg tgcgacgtga
    19501 agtgtgacgt tcccatgcgc accgcccgga gagtctgagg aggtccgggg gcctctcggc
    19561 ccccggacca cgccgtccta gagggtcccg gtgagggctt ccggacggat cggcgtcttg
    19621 ttgatctcca gacccgtcgc ctgccggatc gccgcgatga cggccggggt ggacgagagg
    19681 gtcggggcct cgcccatacc gcgcaggccg tagggggcct tcgggtcggc gagctccagg
    19741 acgtcgaccg gaatggtcgg ggtgtcgagg atggtcggga tcaggtagtc cgtgaaggag
    19801 gggttgcgca ccttcgcggt cttcgggtcc acgatgatct cctccatgat cgcgacgccg
    19861 agaccctggg tggtaccacc ctggatctgg ccgaccacgg aaagcatgtt gagggccttg
    19921 ccgacgtcct gcgcggtcgc cagctcgacg accttgacca ggccgagctc ggtgtccacc
    19981 tcgacgaccg cgcggtgcgc ggcgaaggtg tactggacgt ggccgttgcc ctggccggtc
    20041 cgcaggtcga aggcctcggt gggcgcgtga cggaactcga gctcgaggtc gatggcctcg
    20101 tcctccagga tgtcggcgat gtccgcgagg acctcgccgc cgtcggtgac gaccttgccg
    20161 ccttcgagca gcagctcggc cgtcgcccac gcggggtggt acgagccgtt cttgcggcgg
    20221 ccgatctcca ggagggcctc gcggaccgcc tcacaggtgt tcttcacggc accaccggtc
    20281 atgtacgtct gccgggaggc ggacgtggaa ccggcggagc cgacctgcgt gtcggccggg
    20341 tggatggtca cctgcgtgac acccagctcg gtacgggcga tctgcgtgtg gacggtgata
    20401 ccgccctggc cgacctccgc catggccgtg tggaccatcg cgacgggctc gccgttgatg
    20461 acctcgagcc gcacgcgggc ggtcgagtag tcgtcgaagc cctccgagaa gccgacgttc
    20521 ttgatgccga ccgcgtagcc gacgccgcgg acgacgccct cgccgtgggt ggtgttcgac
    20581 agaccgccgg gcagcgcgcg gacgtccgcg ttctcgccgg cgctctccca ctggcgctcc
    20641 ggaggcatcg ggcgggcctt gacgcggcgc agcagctcgg cgacgggcgc cggggcgtcc
    20701 acgacctggc cggtcggcat gaccgtgccc atctccatgg cgttcagctg gcggaactcg
    20761 accgggtcca tgcccagctt cgccgcgagc ttgtccatct gggcctcgta ggcgaagcag
    20821 gcctggacgg cgccgaagcc gcgcatcgcg ccacagggcg ggttgttcgt gtagagcgcg
    20881 atcgcctcga tgtccacgtc ctccaggacg tagggaccca ccgagaggga ggaggcgttg
    20941 cccacgaccg ccggggaggc ggacgcgtac gcgccaccgt ccaggacgat cttgcacttc
    21001 atgtgcgtga gcttgccgtc cttggtggcg ccgtgctcgt agtagagctt cgccgggtgg
    21061 cggtgcacgt ggccgaagaa ggactcgaac cggttgtaga cgatcttgac cggcttgttc
    21121 gtggccaggg ccaggaggca ggcgtggatc tgcatcgaga tgtcctcgcg gccgccgaag
    21181 gcaccgccga cgcccgagag cgtcatacgg accttctccg ggggcaggcc caggaccggg
    21241 gcgatctgct ggaggtccga gtgcagccac tgggtggcga cgtacagctc gacaccgccg
    21301 tcctcggacg gtacggccag gccggactcc gggccgagga aggcctggtc ctgcatgccg
    21361 aaggtgtact cgccctcgac gatgacgtcg gcgcgcttgc gggcctcctc cacgttgccg
    21421 cggatgatcg gctggcggtg cacgatgttc gggtgcggga cgtgaccgat gtggtggtcg
    21481 tcgcggccct cgtggatcag cggcgcgtcg ggggcgaggg cggaggcctc gtcggtgacg
    21541 agcggcagct cgcggtagtc gatcttgatc ttggccgccg cgcggcgggc ggtctccggg
    21601 tggtcggcgg ccacgagggc gaccggctca ccgtggtgcc gtacccggcc gttggcgagg
    21661 accggggtgt cctggatctc caggccgtag ttcttcatct cggccggcag gtcgtcgtac
    21721 gtcagcaccg agtacacgcc gggcatggcg agcgcctcgg agatgtcgat ggagacgatc
    21781 tcggcgtggg cgacggtgct gcgcagcgtc tggccccaca gcatgtcctc gtgccacatg
    21841 tccgaggagt acgcgaactc gccggtgacc ttgagggtgc cgtccggacg gaggatggac
    21901 tcgccgatgc cgcccttgtt gtgcttctgg gtgacgttcg tcggcgtacc ggcgggcacg
    21961 gtgcgggtgt tctgagccat ggtcagaccg cctctgactg acgggcggcc gcgaggcgga
    22021 ccgcgtcgag gatcttctcg tagcccgtgc agcggcagag gttgccggac agggcctcac
    22081 ggatgtcctg gtcggacggg gaggagttct cctccagcag ggcgtccgcc tggatgagca
    22141 gacccggggt gcagaaaccg cactgcacgg cgccggcgtc gatgaacgcc tgctggatgt
    22201 tggagagctc cacgccc
//
