LOCUS       NZ_CP020555            21368 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. Sge12 chromosome, complete genome.
ACCESSION   NZ_CP020555
VERSION     NZ_CP020555.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Sge12
  ORGANISM  Streptomyces sp. Sge12
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7983613)
  AUTHORS   Tao,M., Xu,J., Xu,M., Liu,K., Zhao,Z. and Peng,Q.
  TITLE     Genome sequence of Streptomyces sp. Sge12, producing unknown
            compounds against rice blast disease
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7983613)
  AUTHORS   Tao,M., Xu,J., Xu,M., Liu,K., Zhao,Z. and Peng,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, Huashan Road 1954, Shanghai 200030,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: RS_HGAP Assembly v. 3; BWA v. 0.7.10; Bowtie v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 85.0x
            Sequencing Technology :: Illumina HiSeq 4000; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:12:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,312
            CDSs (total)                      :: 7,216
            Genes (coding)                    :: 7,106
            CDSs (with protein)               :: 7,106
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 32 of 111
            Pseudo Genes (incomplete)         :: 91 of 111
            Pseudo Genes (internal stop)      :: 8 of 111
            Pseudo Genes (multiple problems)  :: 18 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:35:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 676150
            Orig. end                         :: 697518
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020555.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21368
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21368
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21368
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11368](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11368)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            29..1603
                     /locus_tag="B6R96_RS03185"
                     /old_locus_tag="B6R96_03190"
     CDS             29..1603
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743715.1"
                     /locus_tag="B6R96_RS03185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03190"
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_081521478.1"
                     /transl_table=11
                     /translation="MHDAPDTWAGPPPRSGAAPLVRMRGLSKRFGGTLALASVDLDIHR
                     GSVLALLGPNGAGKSTLIKVLAGVHHADEGHVTVDGHPLGSHAAARSMSFIHQDLGLVP
                     WMTVAENIALGTGYPRHRGLISWRRTRQRCDEALRIVAGHLDPDARIRDLGPAERSLVA
                     IARALATRAGLIVLDEPTATLPAADCARLFDVLHALRDRGHGILYVSHRLDEVYEVADT
                     FAVLRDGRLVDRGPLAGHSPDRLVRAIVGHVPAGSAQAGRVPAAPPAPPAAAAPRLRLD
                     GVRTASTGRVGLELRAGEILGMVGLTGAGHMELGRALAGARPILEGRVLLDGRPYRPRS
                     VHAALDAGVGFVAANRQEEGCAADLTVRENFLANPRASGAPAAHWISPRRERAEALALI
                     DRFSVHPRRSEVPIATLSGGNQQKVMVGRWLRGHLRLLVLEEPTAGVDVGAKATIHRLL
                     DDALDSGLGVLLISTDFEEVAAVCHRALVFVRGSVSAELSGASLTVTELTRTASAMPAI
                     TGTATDR"
     gene            1600..2646
                     /locus_tag="B6R96_RS03190"
                     /old_locus_tag="B6R96_03195"
     CDS             1600..2646
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118389.1"
                     /locus_tag="B6R96_RS03190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03195"
                     /product="ABC transporter permease"
                     /protein_id="WP_081521479.1"
                     /transl_table=11
                     /translation="MTTSPPPSPSPPSPSPSPSPSSRRSLLDHLRGHHLGTYGLVILAA
                     LLFLVFSLVLPDTFPTRDNVSSILSNQSIPAILALGATIPIATGKFDLSMGYGLGLAHV
                     MVLQLIVNAGWPWPLACLTVIVGGALVGVLNGVIVEYVRIDSFIATLGTGSMMYATTGW
                     ITDGSRIVPGPDGLPAAFTGLYDSRFLGLPLPAYYVIALAAALWVVLERLPLGRYMYVI
                     GSSRRTADIIGIPSHRYSVYAFAGSGLVTGLAGVLLAAQQQTGNPSVGLDYLLPAFVGA
                     LLGSTTIKPGRVNALGTVVAVAVLAVGLAGIGQLGADFWATPLFNGATLLIAVGLAGYS
                     ARRRLRTS"
     gene            2680..3840
                     /locus_tag="B6R96_RS03195"
                     /old_locus_tag="B6R96_03200"
     CDS             2680..3840
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118388.1"
                     /locus_tag="B6R96_RS03195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03200"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_081521480.1"
                     /transl_table=11
                     /translation="MYPKDPHRRTGRRSTRTTAALLTASAALVAGCGGGGPSTGAAPPT
                     AGCPTVLASAGAAVAQAEKADTSWHGPTTGPAAVPGKSIVYVAQTMTNPGVAGVAKGVE
                     EAAKAIGWQVRVIDGEGTPAGIQAALSQAITLAPSGIVIGGFDPQLTSQQMARAEAARI
                     PVIGWHAVGSPGPSERPRLFTNVTTKVEDVAKISADWIIARSEGGAGVVLFTDDSIPFA
                     RNKSQLIRKQLATCPGVRLLSYENIPIPDAASRTAQAVSSLLSRFQDEWTYSVAINDLY
                     FADAAPALRAAGKPGAGPPFNIGAGDGDPSAFQRINSEQFQAATVPEPLNQQGWQIVDE
                     FNRAFAEQPASGYVAPVHIATAQNSDGATSWDPSGYREGYLRIWAG"
     gene            complement(3901..4668)
                     /locus_tag="B6R96_RS03200"
                     /old_locus_tag="B6R96_03205"
     CDS             complement(3901..4668)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742178.1"
                     /locus_tag="B6R96_RS03200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03205"
                     /product="NPP1 family protein"
                     /protein_id="WP_237291298.1"
                     /transl_table=11
                     /translation="MRTKRHIRRSLVVLGAALTVVVAVPQVAFAAPPPALPGKAETIEL
                     TYQPAYDYDTDGCYPTPAIGPTGVLNSGLKPTGALNGSCRDASDLANTNGYSRWKCNNG
                     WCAVIYALYFEKDQALPGIELGGHRHDWEHVVVWIQGNEAKYVATSAHGDFNIHSRDQI
                     RWDGNHPKIVYHKDGIGTHCFRAANTNDEPPENHRGTWQFPTLVGWSGYPATLRDKLTQ
                     ADFGSAHFGLKDGSFASHLAEAKPAGIAFDPNQ"
     misc_feature    complement(4636..4638)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5206..6072)
                     /locus_tag="B6R96_RS03205"
                     /old_locus_tag="B6R96_03210"
     CDS             complement(5206..6072)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (13-181). E-value: 9e-17. Score:
                     53.5. Matches aSDomain:
                     nrpspksdomains_B6R96_RS03205_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017945614.1"
                     /locus_tag="B6R96_RS03205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03210"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_053704937.1"
                     /sec_met_domain="adh_short (E-value: 3.3e-32, bitscore:
                     110.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTLPTAPGSSTRTVLITGTSSGIGLAAAIAAARAGWRTVATLRD
                     TGRADALRKAAVEAGVELDIRQLDVVDEASVAAAVEGVIADYGRLDAVVNNAGAGHVGT
                     LELETVADVREVMEVNFFGVLNVSKAALPHLRATGGRLITVTSVGGVVGQPFNEAYCAA
                     KFAVEGYMESLAPVAGAVGVSVTVIEPGAVATEFVNNIDLDLEARIAAAGPYSDALRHY
                     VERTVGQFLNGAQTPEGAAESVMEALTVEHPAFRIQTSDWARDFTGNKLVDQDGSAVIG
                     MTSTWVA"
     aSDomain        complement(5530..6033)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B6R96_RS03205_PKS_KR.1"
                     /evalue="9.00E-17"
                     /label="B6R96_RS03205_PKS_KR.1"
                     /locus_tag="B6R96_RS03205"
                     /protein_end="181"
                     /protein_start="13"
                     /score="53.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVLITGTSSGIGLAAAIAAARAGWRTVATLRDTGRADALRKAAVE
                     AGVELDIRQLDVVDEASVAAAVEGVIADYGRLDAVVNNAGAGHVGTLELETVADVREVM
                     EVNFFGVLNVSKAALPHLRATGGRLITVTSVGGVVGQPFNEAYCAAKFAVEGYMESLAP
                     VAGAV"
     gene            6161..6643
                     /locus_tag="B6R96_RS03210"
                     /old_locus_tag="B6R96_03215"
     CDS             6161..6643
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601811.1"
                     /locus_tag="B6R96_RS03210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03215"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_053174972.1"
                     /transl_table=11
                     /translation="MPKKLTEAEMPTADYAFYGLVWAGTVMTDRVDRALVKAHDLPVSW
                     FEVMLWLASSPEPVPASVLGNSTLLSRSQVSRVVDALQTRGLVTRTPSARDARSVEVAL
                     TEAGRTVFAEADATRREALAPVFTELLDEQDLEALGTVWRKLKAAKAEQAEQERTR"
     gene            complement(6681..7313)
                     /locus_tag="B6R96_RS03215"
                     /old_locus_tag="B6R96_03220"
     CDS             complement(6681..7313)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268184.1"
                     /locus_tag="B6R96_RS03215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03220"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_081521481.1"
                     /transl_table=11
                     /translation="MATPSSKAGTKGVPREHRRRQMLEAATEEFGTHGYAAASLPAIAA
                     RVGVTKTLLHQYLGSKEDLYVACLVPVGDRLLEAVREAMAEGGAAPHTPLRVLHGIFTA
                     LEGRREAWFVLYDTSLPPGGEAARRASEYWAAIDGLAAGGTAELLRAAGSTDPLDADAL
                     KYVWRDLVATLVRWWVKHPEQTPEAMTRRCARLFAAAATIAPDGRPG"
     misc_feature    complement(7327..7343)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.36"
                     /tool="antismash"
     misc_feature    complement(7342..7358)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.13"
                     /tool="antismash"
     gene            7378..8994
                     /locus_tag="B6R96_RS03220"
                     /old_locus_tag="B6R96_03225"
     CDS             7378..8994
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268185.1"
                     /locus_tag="B6R96_RS03220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03225"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_081521482.1"
                     /transl_table=11
                     /translation="MAGTTPQSTSRTRSWWGWGWTDAHPDDAECTAMGALLPGTLGRPL
                     PVPRVSDLEIAGPAAEPPQSLAHLVSTDRGDRAAHSMGKAYRDVARALRGRPGRIPDLV
                     ARPTDDRDVADLLDWAGERQVAVVPYGGGSSVTGGVEYRGDAHRAVMSLDLTTMGRVLE
                     VDTEGRAARIQAGTLGPSLEDQLRPHGLTLRHFPQSFEFSTLGGWLATRAGGHYATGRT
                     HIDDFVQSLRVVTPAGTSSSWRLPASGAGPSPDRLFLGSEGALGVITEAWVRLQERPRH
                     KASAAVSFTDFQDALRAVRALAQSDLSPANCRLLDSGEAALSGAAHDGSSVLVLGFESA
                     DEPVGARLERAVALARSHGARYDAADGADGDREGAPGGDAAVGAWRSAFLRMPYLRDGL
                     VRMGAVAETFETAATWDRIPALIDEVRREVGAAAVKATGHPATVNCRLTHVYPDGAAPY
                     FTVLAAGRAGDEVAVWDELKAVASEVLHRHRATITHHHAVGRDHRPDYDRQRPEPFALA
                     LRAAKGALDPRGILNPGVLVG"
     gene            complement(9098..9985)
                     /locus_tag="B6R96_RS03225"
                     /old_locus_tag="B6R96_03230"
     CDS             complement(9098..9985)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576151.1"
                     /locus_tag="B6R96_RS03225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03230"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_053174965.1"
                     /transl_table=11
                     /translation="MTSTDLTAAAGTSSVFIPGPATPYQGDIARYWDHEARPVNLRLGD
                     VDGLYHHHYGIGDIDHAALGDPADSAYEKKLIAELHRLESAQAELLLQHLGAIERDDTL
                     VDAGCGRGGSMVMAHQRFGCKVEGVTLSAKQADFANRRAEELGIEDHVRARVCNMLSTP
                     FETGQAAGSWNNESSMYVDLHDLFAEHSRVLAVGGRYVTITGCWNPRYGQPSKWVSQIN
                     AHFECNIHSRREYLRAMADNRLVPQAVIDLTPETLPYWELRATSSLVTGIEEAFIESYK
                     DGSFQYVLIAADRV"
     misc_feature    9997..10010
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.68"
                     /tool="antismash"
     gene            complement(10001..11368)
                     /locus_tag="B6R96_RS03230"
                     /old_locus_tag="B6R96_03235"
     CDS             complement(10001..11368)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378420.1"
                     /locus_tag="B6R96_RS03230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03235"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_081521483.1"
                     /sec_met_domain="T1TS (E-value: 1.2e-68, bitscore: 231.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDPGPSPLQSSLPAAAASFGAHILANALAAGVEPAAGAGPVRPS
                     PPSPPALPTGPPVLTPAPASLPVVDESAAPAAAAAAPRPNAAALDRILRGPSGLGTESL
                     HWARSEEVAAAGAATGAATAEPAPVAGRPIPGLYHHPVPEPDPVRVEELSRRIKAWALD
                     EVSLYPDDWEDQFDGFSVGRYMVACHPDAPSIEHLMLATRLMVAENAVDDCYCEDHGGS
                     PIGLGGRLLLAHTALDPLHTTKEYAPQWEASLLSDAPRRAYRSAMEYFVQASTASQADR
                     FRHDMARLHMGYLAEGAWAQTEYVPEVWEYLAMRQFNNFRPCPTITDSVGGYELPADLH
                     AQPAMQRVIALAGNATTIVNDLYSYTKELASPGRHLNLPVVIAERERCSDQEAYLKAVE
                     VHNDLMRDFEAAAAELALACPVPSVQRFLRGVAVWVDGNHYWHQTNTYRYSLPDFW"
     misc_feature    complement(11371..11386)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.42"
                     /tool="antismash"
     gene            complement(11474..12886)
                     /locus_tag="B6R96_RS03235"
                     /old_locus_tag="B6R96_03240"
     CDS             complement(11474..12886)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267883.1"
                     /locus_tag="B6R96_RS03235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03240"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_030389809.1"
                     /transl_table=11
                     /translation="MTVDTSPEAQLEPPRQSSLSTAAARNLASTTKSAPQMQEITSRWL
                     LRMLPWVETKGGTYRVNRRLTYTVGDGTIEFVQDGANVRVIPRELGELALLRGFEDDDV
                     LTALAGRCVQRDFRAGEVIVERGTPAEQIHLIAHGRISQTSVGKYGDDVAVAVLADGDR
                     FGENALLDADATWDYTATAETPGILLTLSRGDFASVLAAAPQLQAHIDRFSMLPQQRQN
                     KHGEAEIAMSAGHTGEAELPGAFVDYELKPREYELSIAQTVLRIHTRVADLYNGPHNQT
                     EEQLRLTIEALRERQEHELINNRDFGLLHNAAFKQRIQTHSGPPTPDDLDELLCRRRGS
                     KFFLAHPRTIAAIGREFNARGLYPDHVDVGGQQVPAWRGVPILPCNKIPISKENTSSVL
                     VMRTGEDNQGVIGLRQTGLPEEYEPGLSVRFMGISEQAIISYLVTTYFSAAILVPDALG
                     VLENVQIARRRD"
     misc_feature    complement(13021..13039)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.09"
                     /tool="antismash"
     misc_feature    13023..13037
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     misc_feature    complement(13024..13039)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            13237..14184
                     /gene="bla"
                     /locus_tag="B6R96_RS03240"
                     /old_locus_tag="B6R96_03245"
     CDS             13237..14184
                     /EC_number="3.5.2.6"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="bla"
                     /gene_functions="resistance (resist) Exo"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601733.1"
                     /locus_tag="B6R96_RS03240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03245"
                     /product="class A beta-lactamase"
                     /protein_id="WP_237291299.1"
                     /transl_table=11
                     /translation="MKTQGASTSRRALLTAGAGVALAAALPVGAARAASASASASVSVS
                     RHGEGEVVARLRELEREYGARLGVYARDTATGRTVAHRADELFPMCSVFKTLAVAAVLR
                     DLDHDGAHLAKRIHYTLQDVTDAGGGSVTERPENIAGGLTVAQLCSAAIAQSDNLAGNL
                     LLRELGGPTAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLALG
                     DALDSGDREQLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRP
                     PLVLSILSTLPEPTAPRDNTLIARTAKLLADALA"
     misc_feature    complement(14401..14417)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.93"
                     /tool="antismash"
     gene            14441..15526
                     /locus_tag="B6R96_RS03245"
                     /old_locus_tag="B6R96_03250"
     CDS             14441..15526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980456.1"
                     /locus_tag="B6R96_RS03245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03250"
                     /product="hypothetical protein"
                     /protein_id="WP_081521485.1"
                     /transl_table=11
                     /translation="MEVTRIVVIGLVIALAVVHYRRTTVDVPDRASARASRKSGLLPQS
                     RQHTGRAAPDPELERAAAAAARGSWEPAARLMAETRERGDWARRSACAAALGSHRAARP
                     DSWLHAWEAAAGPDDADLAVVRAKALVNLAWQQRGGARAKHTSAEQFAGFHATLARVPQ
                     ESARAAELNPADPIPYVCGIWAALGLGHPEEDMLRIWKEITTRDPYHFDAHYAALQYWC
                     AKWRGSEERAMSFAQRAAAEAPVGSLLTVLPLIAWFEHRHSDARSADFRSPHLVSLVDA
                     ALADLAAAPSNHPNAAEVRHLLAYFLTRQKRYDAALAQFRLVDGYVGALPWKYWTDPAE
                     TFCHWRDRAARRAPRARRRPR"
     gene            complement(15558..15938)
                     /locus_tag="B6R96_RS03250"
                     /old_locus_tag="B6R96_03255"
     CDS             complement(15558..15938)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888497.1"
                     /locus_tag="B6R96_RS03250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03255"
                     /product="DUF4440 domain-containing protein"
                     /protein_id="WP_081521486.1"
                     /transl_table=11
                     /translation="MSRETDEVGAAIAGELRLMDPGVRTSQSLVRQLLDPHFVEVGASG
                     RRWTYEEMLAVLPEMDGSAEGGPRYEPSEMTGVLLAPGLVHLTYETVIDGNRARRSSLW
                     RRHGAGAEWQMYYHQATPCPRT"
     gene            complement(15981..16556)
                     /locus_tag="B6R96_RS03255"
                     /old_locus_tag="B6R96_03260"
     CDS             complement(15981..16556)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057874.1"
                     /locus_tag="B6R96_RS03255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03260"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_030389804.1"
                     /transl_table=11
                     /translation="MAADAERPLRADAQRNRDKILAAAVRVFTEQGLEAHFERIAKEAG
                     VGTGTLYRNFPTREALIEAAYRNEVARLCDSVPTLLAAMPPYEALRDWTRRFIDYATAK
                     MGMADAMRAVLAAGTNPYADSRRLIQDALTSLMEACTAADAIRSDITSTDMFAALAGIA
                     LTSAGPEQRAQAERLLDLTLDGLRARRE"
     gene            16703..17434
                     /locus_tag="B6R96_RS03260"
                     /old_locus_tag="B6R96_03265"
     CDS             16703..17434
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-168). E-value: 2.3e-12. Score:
                     39.2. Matches aSDomain:
                     nrpspksdomains_B6R96_RS03260_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015580355.1"
                     /locus_tag="B6R96_RS03260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03265"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_081521487.1"
                     /sec_met_domain="adh_short (E-value: 5.6e-34, bitscore:
                     116.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGIEGKIVAVTGAGSGIGEATALLLAERGAKVVLGARRTERLEA
                     LAARIEKAGGEAAWIRTDVTRRTDLVGLVDLARERYGRLDVLVGNAGVGLISPLDELRV
                     DDWEEMIDVNLKGVLYGIAAALPVFREQGSGHFVNVVSTAGLRVVPLQSVYAGTKNAVR
                     TISEGLRQEAGDSLRVTVVSPGAVRTDFTERMGPEARDRIDRMMETALSPDAVARAIAF
                     AIEQPDGVDVGDIVVRPTAQA"
     aSDomain        16727..17206
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B6R96_RS03260_PKS_KR.1"
                     /evalue="2.30E-12"
                     /label="B6R96_RS03260_PKS_KR.1"
                     /locus_tag="B6R96_RS03260"
                     /protein_end="168"
                     /protein_start="8"
                     /score="39.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVTGAGSGIGEATALLLAERGAKVVLGARRTERLEALAARIEKA
                     GGEAAWIRTDVTRRTDLVGLVDLARERYGRLDVLVGNAGVGLISPLDELRVDDWEEMID
                     VNLKGVLYGIAAALPVFREQGSGHFVNVVSTAGLRVVPLQSVYAGTKNAVRTISEG"
     CDS_motif       16733..16810
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B6R96_RS03260_0001"
                     /evalue="3.30E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="B6R96_RS03260"
                     /protein_end="36"
                     /protein_start="10"
                     /score="13.3"
                     /tool="antismash"
                     /translation="VTGAGSGIGEATALLLAERGAKVVLG"
     gene            complement(17514..19244)
                     /locus_tag="B6R96_RS03265"
                     /old_locus_tag="B6R96_03270"
     CDS             complement(17514..19244)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088719.1"
                     /locus_tag="B6R96_RS03265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03270"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_081521488.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.5e-19, bitscore:
                     68.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADALLFNPHTYDPAHFDPETRRLLRATVDWFESRGKRRLIEDYR
                     SRAWLADFLAFSAKEGLFATFLTPAAAAGEGESDKRWDTARIAALNEIFGFYGLDYWYA
                     WQVTILGLGPVWQSDNAEARERAAQLLSEGEVFAFGLSEKSHGADIYSTDMLLQPDSDG
                     AGGFRASGSKYYIGNGNAAGLVSVFGRRTDIEGPDGYVFFAADSRHAAYHLVKNVVDSS
                     KYVSEFRLDDYPVRAEDVLHTGRAAFDAALNTVNVGKFNLCTASIGICEHAMYEAVTHA
                     HNRVLYGRPVTAFPHVRRELADAYVRLVGMKLFSDRAVDYFRTAGPDDRRYLLFNPMTK
                     MKVTTEGEKVIDLMWDVIAAKGFEKDNYFAQAAIEIRGLPKLEGTVHVNLALILKFMHN
                     HLLNPAEYPEVPTRLDAADDAFLFQQGPARGLGSVRFHDWRTAYDAYAAVPNVARFREQ
                     ADALCAFVATVAPDEEQSRDLDFLLSVGQLFALVVYGQLVLEQARLTDLDESVLDELFS
                     VLVRDFSGHAVELYGKDSATAAQQDWALGAVRRPVVDEARAARVWARVEALSGTYEMAP
                     "
     gene            complement(19335..19940)
                     /locus_tag="B6R96_RS03270"
                     /old_locus_tag="B6R96_03275"
     CDS             complement(19335..19940)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122699.1"
                     /locus_tag="B6R96_RS03270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03275"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_081521489.1"
                     /transl_table=11
                     /translation="MALDHAILVSLLEKPGSGYELARRFDRSIGYFWTATHQQIYRVLG
                     RMEGDGLLAVREVPQQGRPDKKEYSVAGPGRAALAGWLHEPIEPESLRHDLAVKIRGVA
                     FDDPAALIQEVERHHRAHSDRLARYLAGELRDFTGPDAPAPLDAGQELQHVVLRGGIAY
                     ERMTIAWLDDVLATLHRLGGTASTAATTATTATTAATA"
     gene            20172..20777
                     /locus_tag="B6R96_RS03275"
                     /old_locus_tag="B6R96_03280"
     CDS             20172..20777
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970264.1"
                     /locus_tag="B6R96_RS03275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_03280"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_081521490.1"
                     /transl_table=11
                     /translation="MSTAKDLFIIAMDPPPDRPVGQGDLSLALAGAELIDLLDAQAAAL
                     DGDRIVPGEPSELHDPLLSEAASALTRHTPYERVDEWLWRRGRDLSAAYQAALEEAGEL
                     TRGRRGLLPFGSDRMEVADTPARRRALGRQEEDEPVLAALASVVGLRSDDPEAEPRPGD
                     EAVTTVLAVVNDAVMELEAVRQRRTIENAAYANMWRSP"
ORIGIN
        1 actcggaggc cgacccccgg agaagtctgt gcatgacgct cccgacacct gggcgggccc
       61 acccccgcgc tccggtgccg cgcccctcgt ccggatgcgc ggcctgagca agcggttcgg
      121 cggcacgctc gcgctggcct cggtcgacct cgacatccac cgcggcagtg tcctcgccct
      181 gctcggcccc aacggagcgg gaaagtccac cctcatcaag gtgctcgccg gggtccacca
      241 cgccgacgag ggccacgtca cggtggacgg gcatccgctc ggcagccacg ccgcggcccg
      301 cagcatgtcc ttcatccacc aggacctcgg cctggtcccg tggatgacgg tggccgagaa
      361 catcgccctg ggcacgggct atccccgcca ccgcggactg atctcctggc ggcggacccg
      421 gcagcgctgc gacgaggccc tgcggatcgt cgccggccac ctggaccccg acgcccggat
      481 ccgcgacctc ggccccgccg aacgctcgct cgtcgccatc gcccgcgccc tcgccacccg
      541 ggccgggctc atcgtcctcg acgagccgac cgccaccctc cccgccgccg actgcgcacg
      601 gctcttcgac gtcctgcacg ccctgcgcga ccgcgggcac ggcatcctct acgtcagcca
      661 ccgcctcgac gaggtgtacg aggtcgccga caccttcgcc gtcctgcgcg acggccggct
      721 ggtcgaccgg ggtcccctgg ccggccacag cccggaccgt ctggtgcggg cgatcgtggg
      781 ccacgtaccg gccggctccg ctcaggccgg ccgggtaccc gccgcaccgc ccgcaccgcc
      841 cgccgcggcc gcgccccggc tgcgcctcga cggggtgcgg accgcgtcca ccgggcgggt
      901 cgggctggag ctgcgggccg gggagatcct cggcatggtg ggcctgaccg gcgccggtca
      961 catggagctg ggccgcgccc tggccggcgc ccggccgatc ctggagggcc gggtgctgct
     1021 ggacgggcgg ccctaccggc cgcgttcggt gcacgccgcg ctcgacgccg gtgtcggctt
     1081 cgtggcggcc aaccgtcagg aggagggctg cgccgccgac ctgaccgtgc gggagaactt
     1141 cctggcgaac ccgcgggcgt ccggcgcccc ggccgcgcac tggatcagcc cccgtcgcga
     1201 gcgcgccgag gccctcgccc tcatcgaccg gttctcggtg catccccgca ggagcgaggt
     1261 gccgatcgcc accctgtccg gcgggaacca gcagaaggtg atggtcggcc gatggctccg
     1321 ggggcacctg cgcctgctcg tcctcgagga gccgacggcc ggggtggacg tcggcgccaa
     1381 ggccaccatc caccggctgc tcgacgacgc actcgactcc ggcctcggcg tcctgctcat
     1441 ctccaccgat ttcgaagagg tcgcggccgt gtgccatcgc gcgctggtgt tcgtccgcgg
     1501 gagcgtgagc gccgagctga gcggtgcgtc cctcaccgtc accgaactca cccgcaccgc
     1561 ctcggcgatg cccgcgatca ccgggaccgc gaccgaccga tgaccacctc acccccgccc
     1621 tcaccctcgc ccccgtcccc ttccccgtcc ccttccccgt cctcgcggcg atccctgctg
     1681 gaccacctgc gtggccacca cctgggcacc tacggcctgg tgatcctcgc cgccctgctg
     1741 ttcctggtct tctccctcgt cctgccggac accttcccca cccgggacaa cgtctcctcg
     1801 atcctctcca accagtccat ccccgccatc ctcgcgctcg gcgcgacgat ccccatcgcc
     1861 accggaaagt tcgacctgtc gatgggctac ggcctcggcc tggcccacgt gatggtgctc
     1921 cagctgatcg tcaacgcggg ctggccctgg ccgctcgcct gtctgaccgt catcgtcggc
     1981 ggggcactgg tcggcgtcct caacggcgtc atcgtcgagt acgtgcggat cgactccttc
     2041 atcgccaccc tcggcaccgg cagcatgatg tacgccacca ccggctggat caccgacggc
     2101 tcccggatcg tccccggccc ggacggcctg cccgccgcct tcaccggcct ctacgactcc
     2161 cggttcctcg gcctgcccct gcccgcctac tacgtcatcg ccctcgcggc cgcgctctgg
     2221 gtggtcctgg agcggctgcc cctcggccgg tacatgtacg tcatcggctc cagccggcgc
     2281 accgccgaca tcatcggcat ccccagccac cggtactccg tctacgcctt cgccggatcg
     2341 ggcctggtca ccggcctcgc cggggtcctc ctcgccgccc agcagcagac cgggaacccg
     2401 agcgtcgggc tggactacct gctgcccgcc ttcgtcggcg ccctcctggg gtccaccacg
     2461 atcaaacccg gccgcgtcaa cgccctcggc accgtcgtgg ccgtcgccgt cctcgccgtc
     2521 ggcctcgccg gcatcggcca gctcggcgcc gacttctggg ccacaccgct gttcaacggc
     2581 gccaccctgc tcatcgccgt cggcctggcc ggctactccg cccgccgccg actgcgcacc
     2641 tcctagaaaa gtccgtacgc gcaccgcgtc aggagcaccg tgtacccgaa ggacccgcac
     2701 cgcagaaccg gccgccggag cacccgcacg accgccgccc tgctgaccgc gagcgccgcc
     2761 ctcgtcgccg gctgcggggg cggcggcccc tccaccggcg ccgcgccgcc cacggcgggc
     2821 tgccccaccg tcctggcgag cgccggggcg gccgtggcgc aggccgagaa ggccgacacc
     2881 tcctggcacg gcccgaccac cggccccgcg gcggtgcccg gcaagtcgat cgtctacgtc
     2941 gcgcagacca tgaccaaccc cggcgtcgcg ggcgtcgcga agggcgtcga ggaggccgcg
     3001 aaggccatcg gctggcaggt ccgggtgatc gacggggaag gcacgcccgc cgggatccag
     3061 gcggcgctca gccaggccat caccctggcg ccctcgggca tcgtcatcgg cggcttcgac
     3121 ccccagctga cctcgcagca gatggcacgg gccgaggcgg cgcggatccc ggtcatcggc
     3181 tggcacgcgg tgggctcccc cggcccgagc gagcgcccca ggctgttcac caacgtcacc
     3241 acgaaggtgg aggacgtggc gaagatcagc gcggattgga tcatcgcccg gtccgagggc
     3301 ggtgccggtg tcgtcctgtt caccgacgac tcgatcccct tcgcccggaa caagtcacag
     3361 ctgatccgca agcagctcgc cacctgtccc ggcgtacgcc tgctctcgta cgagaacatc
     3421 cccatcccgg acgccgcgag ccgcaccgcg caggccgtct cctcgctgct ctcacgcttc
     3481 caggacgagt ggacgtactc ggtcgccatc aacgacctct acttcgccga cgcggctccg
     3541 gccctgcggg cggccgggaa accgggggcc gggccgccct tcaacatcgg tgcgggtgac
     3601 ggggacccct ccgccttcca gcggatcaac agcgagcagt tccaggccgc caccgtcccc
     3661 gagccgctca accagcaggg ctggcagatc gtcgacgagt tcaaccgcgc cttcgccgag
     3721 cagcccgcca gcggctacgt ggcgcccgtg cacatcgcca ccgcgcagaa cagcgacggc
     3781 gccacgtcct gggacccgtc cggataccgc gaggggtacc tcaggatctg ggccggctga
     3841 cggcacggca gtacgggcac cggtcccgcg cggtgcgggg ccggtgcccg gcggcccgtc
     3901 ctactggttg gggtcgaagg cgatgcccgc cggcttggcc tccgccaggt gggaggcgaa
     3961 ggagccgtcc ttcaggccga agtgcgcgct gccgaagtcg gcctgggtga gcttgtcccg
     4021 cagggtcgcc ggatagcccg accagccgac gagcgtgggg aactgccagg tgccgcggtg
     4081 gttctcgggc ggctcgtcgt tggtgttggc cgcccggaag cagtgcgtgc cgatgccgtc
     4141 cttgtggtag acgatcttgg ggtggttgcc gtcccagcgg atctggtccc gggagtggat
     4201 gttgaagtcc ccgtgggccg aggtcgcgac gtacttggcc tcgttgccct ggatccagac
     4261 gaccacgtgc tcccagtcgt ggcggtggcc gccgagctcg atgccgggca gggcctggtc
     4321 cttctcgaag tacagcgcgt agatgacggc gcaccagccg ttgttgcact tccagcggga
     4381 gtagccgttg gtgttggcga ggtccgaggc gtcccggcag ctgccgttga gggctccggt
     4441 gggcttgagg ccgctgttca gcactccggt cgggcctatg gcgggtgtcg ggtagcagcc
     4501 gtcggtgtcg tagtcgtagg ccggctggta ggtcagctcg atcgtctcgg ccttgcccgg
     4561 gagcgccggg ggcggcgccg cgaaggccac ctgggggacg gcgacgacca ccgtgagggc
     4621 ggcgccgaga accactaatg atctccgtat gtgacgtttc gtccgcaaaa cgggcctcct
     4681 ggccgaccgg gtgcgagggg tggcggacgc atcgcgacgg ggcaccgtcg accgacacgc
     4741 cgggagcatc attcgcgaac cggtgtggcg cggcaagggg ctgggcggac tccgttccct
     4801 gcatgccgat tgggccggaa aggccgtgta cgcaagggaa gttggcgcaa tgtcagggat
     4861 gggcggggcg atggcgcgga cggagggacg ggcggatgga cgaacaccgc cgccggccgg
     4921 ggtacgaccg ggggcggcgg cggtgtgtca cacggtcatc gtcagaggac gttcatcagg
     4981 atgatggcca tgaggtcgag gaggatgacg gcgacgacgg cgccgatcat gatccaggcc
     5041 ttgcgcgatt cgtccatgcg tacgagtcac ctcccggctc gggcggtacg ggcccgccgc
     5101 gcgcggcccc ggaggggacc gcacgggcga ctcgtccgcc ttcggccatg atgacccggt
     5161 tccgcgcgcg gcacaggtcg gcgcgccgcc cctgccgggc cgtctctagg ccacccaggt
     5221 cgaggtcatg ccgatgaccg ccgagccgtc ctggtcgacc agcttgttcc cggtgaagtc
     5281 gcgggcccag tcggaggtct ggatgcggaa cgcggggtgc tccacggtca gagcctccat
     5341 gaccgactcg gcggcgccct cgggcgtctg cgcgccgttc aggaactggc cgacggtgcg
     5401 ctcgacgtag tggcgcagcg cgtcggagta ggggccggcc gcggcgatgc gggcttcgag
     5461 gtcgaggtcg atgttgttca cgaactcggt cgccacggcg cccggctcga tgacggtgac
     5521 gctcaccccg acggcgcccg cgacgggtgc caggctctcc atgtacccct cgacggcgaa
     5581 cttggcggcg cagtaggcct cgttgaaggg ctggccgacg acgccgccga cgctggtgac
     5641 cgtgatcagg cggccgccgg tggcccgcag gtgcggcagg gccgccttgg agacgttcag
     5701 cacgccgaag aagttgacct ccatgacctc acggacgtcg gcgacggttt ccagctccag
     5761 agtgcccacg tgcccggcgc cggcgttgtt cacgacggca tcgagccggc cgtagtcggc
     5821 gatcacgccc tccacggcgg cggcgacgga ggcctcgtcg acgacgtcga gctgtcggat
     5881 gtcgagctcc acgcccgcct cgacggcggc cttgcgcagg gcgtcggctc ggccggtgtc
     5941 acgcagggtg gcgaccgtcc gccagccggc gcgagcggcg gcgatcgcgg cggccaggcc
     6001 gatgccggag gaggtgccgg tgatcaggac ggtgcgggtg gagctgccgg gagcggtggg
     6061 gagggtggac atggcggggc ctttcatgag gggtgattta tgtgcgtgca cacacaccat
     6121 aaaattatgt gcgtgcgcac gcaagctcta gactgccgac atgccgaaga agctcaccga
     6181 agccgagatg ccgacggccg actacgcctt ctacgggctg gtgtgggccg ggaccgtcat
     6241 gaccgaccgc gtcgaccggg ccctggtcaa ggcgcacgac ctgcccgtgt cctggttcga
     6301 ggtcatgctg tggctggcct ccagcccgga gccggtgccc gcttccgtcc tcggcaacag
     6361 caccctgctc agccgcagcc aggtctcccg cgtggtggac gccctgcaga cccggggcct
     6421 ggtcacccgt acgccctcgg cgcgcgacgc gcggtcggtg gaggtggccc tcacggaggc
     6481 gggacgtacg gtgttcgccg aggccgacgc gacccggcgg gaggccctgg ccccggtctt
     6541 caccgagctc ctcgacgagc aggacctgga ggcgctgggc accgtatggc gcaagctcaa
     6601 ggccgcgaag gccgaacagg ccgaacagga gcgcacccgg tagacctcac cgaccccgcc
     6661 ggcccgccgc gggcccccgt tcagccgggc cggccgtcgg gggcgatggt ggcggcggcc
     6721 gcgaagaggc gggcgcagcg gcgggtcatg gcctccggcg tctgctccgg gtgcttgacc
     6781 caccagcgga cgagggtggc gacgaggtcc cgccagacgt acttgagcgc gtcggcgtcc
     6841 agcgggtccg tggagccggc cgcgcgcagc agttccgcgg taccgcccgc ggccagaccg
     6901 tcgatggccg cccagtactc cgaggcccgg cgggccgcct caccaccggg cggcaagctg
     6961 gtgtcgtaga gcacgaacca cgcctcccgc cggccctcca gggcggtgaa gatgccgtgg
     7021 agcacgcgca gcggggtgtg cggcgcggcc ccgccctcgg ccatcgcctc gcggacggcc
     7081 tccagcagcc ggtccccgac gggcaccagg caggcgacgt acaggtcctc cttgctgccg
     7141 aggtactggt gcagcagcgt cttggtgacg cccacccgtg cggcgatcgc ggggagcgag
     7201 gcggcggcgt agccatgggt gccgaactcc tccgtggccg cctccagcat ctgccggcgg
     7261 cggtgctccc gcgggactcc cttggtgccg gctttcgagg aaggggttgc catgagccga
     7321 tattatcagt aggtaattta ccgctaggta aattacctcg acccctggag cgccgccatg
     7381 gccggcacca ccccgcagtc cacgtcccgc acccgctcct ggtggggctg gggctggacg
     7441 gacgcccatc ccgacgacgc ggaatgcacc gcgatgggcg ccctgctccc cggcaccctc
     7501 ggccgcccgc tccccgtgcc ccgcgtgagc gacctggaga tcgccggccc ggccgccgaa
     7561 cccccgcaga gcctcgccca cctggtcagc accgatcgcg gggaccgcgc cgcccactcc
     7621 atgggcaagg cctaccgcga cgtggcgcgc gccctgcgcg gccgccccgg ccggatcccc
     7681 gacctcgtgg cccggcccac ggacgaccgg gacgtggccg acctgctgga ctgggccggg
     7741 gaacgacagg tcgccgtcgt cccctacggc gggggatcct cggtcaccgg gggcgtcgag
     7801 taccgcggcg acgcccaccg ggccgtgatg tccctcgacc tgaccacgat gggccgcgtg
     7861 ctggaggtcg acaccgaggg ccgggcggcc cgcatccagg ccggcaccct cgggccgagc
     7921 ctggaggacc agctgcgccc gcacggcctc accctgcggc acttcccgca gagcttcgag
     7981 ttctccaccc tcggcggctg gctcgccacc cgggccggcg gccactacgc caccggccgg
     8041 acccacatcg acgacttcgt acagtcgctg cgcgtcgtca ccccggccgg caccagcagt
     8101 tcgtggcggc tgcccgcctc cggggccggg ccctcccccg accgcctgtt cctcggctcc
     8161 gagggagccc tcggcgtcat caccgaagcc tgggtccgcc tccaggaacg cccccgccac
     8221 aaggcctccg ccgcggtctc cttcacggac ttccaggacg cgctccgggc ggtgcgcgcc
     8281 ctcgcacagt ccgacctctc ccccgccaac tgccggctgc tggactccgg tgaggccgca
     8341 ctgtcgggtg cggcgcacga cggcagctcc gtactggtgc tgggattcga gtcggcggac
     8401 gaaccggtgg gcgcccgcct cgaacgggcc gtcgcgctgg cccgctcgca cggcgcccgg
     8461 tacgacgcgg cggacggggc cgacggcgac cgggaggggg cccccggcgg cgacgcagcc
     8521 gtcggagcgt ggcgctcggc cttcctgcgg atgccctacc tccgtgacgg tctggtcagg
     8581 atgggggcgg tggcggagac cttcgaaacg gcggccacct gggaccggat ccccgcactg
     8641 atcgacgagg tacgcaggga ggtcggcgcg gcggcggtca aggccaccgg acaccccgcg
     8701 accgtcaact gccgtctgac acacgtgtat ccggacggcg ctgcgcccta cttcaccgtc
     8761 ctcgcggccg gccgggccgg tgacgaggtg gccgtctggg acgaactgaa agccgtcgcg
     8821 agcgaggtcc tgcaccgcca ccgggccacc atcacccacc accacgccgt cggccgggac
     8881 caccgcccgg actacgaccg ccagcgcccc gagcccttcg ccctcgccct gcgggccgcg
     8941 aagggggcgc tcgatccgcg gggcatcctc aaccccgggg tgctggtggg ctgatcgggg
     9001 ccgggccgcc ccccggagca cccgaagcac cccgaagggg ccggggccgt cggacgacgg
     9061 ccccggcccc ttcggccggc gttcggtgag cgtccgctca gacgcggtcg gccgcgatca
     9121 ggacgtactg gaaggagccg tccttgtagg actcgatgaa cgcctcctcg atgccggtga
     9181 ccagggagga cgtggcccgc agctcccagt acggcagcgt ctcgggggtc aggtcgatca
     9241 cggcctgcgg cacgaggcgg ttgtcggcca tcgcccgcag gtactcgcgg cgggagtgga
     9301 tgttgcactc gaagtgcgcg ttgatctggg agacccactt cgagggctgg ccgtaccgcg
     9361 ggttccagca gccggtgatg gtcacgtagc ggccgccgac cgcgaggacg cgggagtgct
     9421 cggcgaacag gtcgtggagg tccacgtaca tgctcgactc gttgttccac gagcccgcgg
     9481 cctgcccggt ctcgaagggg gtgctgagca tgttgcagac gcgggcccgg acgtggtcct
     9541 cgatgccgag ttcctcggcg cgccggttgg cgaagtcggc ctgcttggcc gacagggtga
     9601 caccctccac cttgcacccg aagcgctggt gggccatgac catggagccg ccgcggccgc
     9661 agccggcgtc gacgagggtg tcgtcgcgct cgatggcgcc gaggtgctgg aggagcagtt
     9721 cggcctgcgc cgactccaag cggtggagct cggcgatcag cttcttctca taggcgctgt
     9781 cggcggggtc accgagagcg gcgtggtcga tgtcgccgat gccgtagtgg tggtggtaaa
     9841 ggccgtcgac gtcgccgagc cggaggttca cgggcctggc ctcgtggtcc cagtaacggg
     9901 cgatgtcacc ctgataaggg gtcgccgggc cggggatgaa cacggaggag gtaccggcag
     9961 cggcggtgag atcggtgcta gtcatggaca attcccatct ttaccagaaa tcgggcaggc
    10021 tgtagcgata ggtgttggtc tggtgccagt agtggttgcc gtcgacccat acggccacgc
    10081 cccgcaggaa gcgctgcacg ctcgggacgg ggcaggcgag ggccagctcg gcggccgcgg
    10141 cctcgaagtc gcgcatgagg tcgttgtgga cctccaccgc cttcagatag gcctcctggt
    10201 cggagcacct ctcgcgttcg gcgatcacca ccggcaggtt caggtggcgt ccgggactgg
    10261 ccagttcctt ggtgtaggag tacaggtcgt tgacgatcgt ggtggcgttc ccggcgagcg
    10321 cgatcacgcg ctgcatggcg ggctgcgcgt ggaggtccgc gggcagttcg tacccgccga
    10381 ccgagtcggt gatggtgggg caggggcgga agttgttgaa ctgccgcatc gccaggtact
    10441 cccacacctc cgggacgtac tccgtctgcg cccaggcccc ttcggcgaga tagcccatgt
    10501 gcagtcgggc catgtcgtgg cggaaccggt cggcctggga ggcggtgctc gcctggacga
    10561 agtactccat ggcggagcgg taggcgcgcc ggggcgcgtc cgagagcagc gacgcctccc
    10621 actgcggcgc gtactccttc gtcgtgtgga gcggatcgag ggcggtatgg gccagcagca
    10681 gccgtccgcc gaggccgatg ggcgaaccgc cgtggtcctc gcagtagcag tcgtcgaccg
    10741 cgttctcggc gaccatcagg cgggtggcga gcatcaggtg ctcgatgctg ggggcgtccg
    10801 gatggcaggc gaccatgtag cgcccgacgg agaatccgtc gaactggtcc tcccagtcgt
    10861 ccggatacaa cgagacctcg tccagcgccc aggccttgat cctgcggctg agctcctcca
    10921 cccgcaccgg atcgggctcc ggcaccgggt ggtggtagag gcccgggatc ggacggcccg
    10981 cgaccggcgc cggctcggcg gtcgcggcgc cggtcgcggc gcccgccgcg gccacctcct
    11041 cgctgcgggc ccagtgcagg ctctccgtgc ccaggccact gggcccgcgc aggatccggt
    11101 ccagggcggc ggcgttcggc cgcggcgcgg cggcggcagc agcgggggcc gcgctctcgt
    11161 cgaccacggg tagggatgcg ggcgcgggcg tcagtacggg gggaccggtg ggcagggcgg
    11221 gcggcgacgg cggcgagggc cggacgggcc cggcgccggc ggcgggttcg acaccggcgg
    11281 ccagggcgtt ggcgaggatg tgggccccga aggaggccgc ggcggcaggc aggctcgact
    11341 gcagagggga aggcccagga tcgggcatcc gtaactcctt ggtgacgtaa gtggtttgtc
    11401 ccggatcccg ggcgtgctcg gcgggccagg acaggcacgg gtcctggctg tcgcggccgt
    11461 cgggcaggtc ctcttagtcc cgcctgcggg cgatctgcac gttctccagc acaccgagcg
    11521 cgtcgggcac caggatggcg gcggagaagt aggtggtgac caggtaggag atgatcgcct
    11581 gttcgctgat ccccatgaag cggaccgaca ggcccggctc gtactcctcg gggagtccgg
    11641 tctggcgcag gccgatgacg ccctggttgt cctcgcccgt tcgcatgacg agcaccgagc
    11701 tggtgttctc cttgctgatc gggatcttgt tgcagggcag gatcgggacc ccgcgccagg
    11761 ccgggacctg ctgcccgccg acgtcgacgt ggtccgggta gagcccgcgg gcgttgaact
    11821 cgcgcccgat cgcggcgatc gtccgggggt gcgcgaggaa gaacttggag ccgcggcggc
    11881 ggcacaggag ctcgtcgagg tcgtccgggg tgggcgggcc ggagtgggtc tggatccgct
    11941 gcttgaaggc ggcgttgtgg agcagaccga agtcccggtt gttgatcagc tcgtgctcct
    12001 ggcgctcgcg cagcgcctcg atggtcagcc tgagctgctc ctcggtctgg ttgtgcggcc
    12061 cgttgtacag gtcggcgacc ctggtgtgga tgcgcagcac ggtctgggcg atggagagtt
    12121 cgtactcgcg cggcttgagc tcgtagtcca cgaaggcgcc gggcagctcc gcctcgccgg
    12181 tgtggccggc cgacatcgcg atctcggcct cgccgtgctt gttctggcgc tgctgcggga
    12241 gcatgctgaa ccggtcgatg tgggcctgga gctgcggcgc cgcggcgagc acggaggcga
    12301 agtcgccgcg ggagagggtg agcaggatgc cgggggtctc ggcggtggcc gtgtagtccc
    12361 aggtggcgtc ggcgtccagc agggcgttct cgccgaaccg gtcgccgtcc gcgaggacgg
    12421 cgacggcgac gtcgtcaccg tacttgccga cggaggtctg gctgatccgg ccgtgggcga
    12481 tcaggtggat ctgctcggcg ggggtaccgc gctcgacgat cacctcaccg gcacggaagt
    12541 cgcgctggac gcagcggccg gcgagtgcgg tcagcacgtc gtcgtcctcg aagccgcgca
    12601 gcagggccag ttcgccgagc tcgcgcggga tcacgcggac gttcgcgccg tcctggacga
    12661 actcgatggt cccgtcgccg acggtgtacg tcagtcggcg gttgacccgg taggtcccgc
    12721 ccttggtctc cacccagggg agcatccgca gcagccagcg ggaggtgatc tcctgcatct
    12781 gcggggcgga cttggtcgtg ctggcaaggt tgcgggcggc ggccgtgctc aggctggact
    12841 gccgcggcgg ctccaactgc gcttccgggc tggtgtcaac ggtcatcggg cgagctctcc
    12901 ttcgtaaggg cggtggtccg cgggtacgcg cgtcaccaga gaacgaggaa aaagggggcg
    12961 aatatcaggg aatccgtcca gatccggggg aacagtaacg tcccggtacg cccacttgag
    13021 cctgaaaacc gttggcatta gctcgatgca gtgatctcgt ccggcaggtg gtttgccggg
    13081 gttatggatg atattcggcc ttgttcacga acacggccca aaagcggctg aaaagcgtgc
    13141 gtcgcacgct ccgtggaccg cttgcacgcg gaaccgaaat gatcacgttt gatgtcttcg
    13201 ctctcacatg accggccagg aagaggagaa cccgacgtga agacccaggg cgcatcaacg
    13261 tcccgtcgcg cactgctgac cgcgggggcg ggggtggctc tggccgccgc gctgccggtg
    13321 ggcgcggccc gtgccgcgtc cgcatccgca tccgcgtccg tgtccgtgtc ccggcacggc
    13381 gagggggagg tcgtggcgcg actgcgcgaa ctggagcgcg agtacggggc gcggctgggt
    13441 gtgtacgcgc gggacacggc caccggacgc accgtggcgc accgggccga cgaactgttc
    13501 cccatgtgct cggtgttcaa gacgctcgca gtggccgccg tgctgcgtga cctcgaccac
    13561 gacggcgccc acctcgccaa gcgcatccac tacaccctcc aggacgtcac cgacgcgggc
    13621 ggcggctcgg tcacggaacg gcccgagaac atcgcgggcg gcctcaccgt ggcgcaactc
    13681 tgctccgccg ccatcgccca gagcgacaac ttggcgggca acctgctgct gcgcgagctc
    13741 ggcggcccca ccgcggtcac ccgcttctgc cgctcgctgg gcgaccgtac gacccggctc
    13801 gaccggtggg agcccgcgct gaactcggcg gagccctcgc gggtgacgga caccacgagc
    13861 ccccgcgcga tcgggcggac gtacgcccgc ctcgcgctcg gcgacgcgct ggactccggg
    13921 gaccgtgagc agctgaaccg gtggctgctg tccaacacca ccagtgccga ccgcctgcgg
    13981 gccggcctgc cgaaggactg ggccgtcgcg gacaagacgg gcgccggatc gtacgggacg
    14041 aacaacaacg tgggcatcgc ctggccgccg ggacgcccgc cgctggtcct gtccatcctc
    14101 tcgaccctgc cggagccgac ggcgccgcgc gacaacacgc tgatcgcccg caccgcgaag
    14161 ctgctggcgg acgcgctcgc ctgacggcgg cccgtacggc cgcccgggga ccccgctcgg
    14221 cctcgtcgag gcggagcggg gtccccggcg ggccggggcg tacggcacgc cgcgggccga
    14281 acggcagcgg aggtagcccc gggcaggtac cggcagacct tgcggggcgg gcgccatgat
    14341 gccgccccac cagcggaaac gtatttgcgg aggatcgcac caccacgtca tactcccggg
    14401 tccccacttt tcgatcactc ctcccccagg ggctcccacc gtggaagtca cacgcatcgt
    14461 cgtcatcggg ctcgtcatcg ccctggcggt cgtccactac cgccgcacca ccgtcgatgt
    14521 cccggaccgg gcttcggccc gcgcctcccg gaagtcgggg ctccttccgc agtccaggca
    14581 gcacaccggc cgggccgcgc ccgatcccga gctggagcgg gcggccgccg cggccgcccg
    14641 gggcagttgg gagccggccg cacggttgat ggccgagacc agggagcgcg gcgactgggc
    14701 acgccgctcc gcctgcgccg ccgccctcgg ctcccaccga gccgcgcgcc ccgacagctg
    14761 gttgcacgcg tgggaggccg ctgccgggcc ggacgacgcc gacctcgcag tggtacgggc
    14821 gaaggcgctg gtcaacctgg cctggcagca gcgtggcggc gcccgggcga agcacaccag
    14881 cgcggagcag ttcgccggat tccacgccac actggcccgg gtaccgcaag agagcgcccg
    14941 cgcggccgag ttgaacccgg ccgacccgat tccgtatgtc tgcgggatat gggcggcgct
    15001 gggcctcggc caccccgaag aggacatgct gcggatctgg aaggagatca ccacccgcga
    15061 cccgtaccac ttcgacgcgc actacgcggc gctccagtac tggtgcgcga agtggcgcgg
    15121 ctcggaggag cgcgccatgt ccttcgcgca gcgggcggcg gccgaggcgc cggtcggcag
    15181 cctgctcacc gtgctgccgc tgatcgcctg gttcgagcac cgtcactcgg acgcgcgttc
    15241 cgccgacttc cgctcaccgc acctggtctc gctggtcgat gccgctctgg ccgacctcgc
    15301 cgcggccccc tcgaaccatc cgaacgccgc cgaggtgcgt cacctgctgg cctacttcct
    15361 gacccggcag aagcggtacg acgcggcgct ggcgcagttc cgtctggtcg acggctacgt
    15421 gggcgccctc ccgtggaagt actggaccga cccggcagaa accttctgcc actggcgcga
    15481 ccgcgcggcc cgccgagccc cccgagcccg ccgccgcccc cgctgaaccg ccggcgcccg
    15541 tcggccccgg cggggcccta agtcctcgga cagggggtgg cctggtggta gtacatctgc
    15601 cactcggctc ccgcgccgtg ccggcgccag agcgagctcc gccgggcccg atttccgtcg
    15661 atcacggtct cgtaggtgag gtgcaccagc ccgggtgcca gcaggacacc ggtcatctcc
    15721 gagggctcat agcgcgggcc gccctccgca gaaccgtcca tctccggcag cacggcgagc
    15781 atttcctcat acgtccaccg ccggcccgag gcgcccacct ccacgaagtg cgggtcgagg
    15841 agctgccgga ccagcgactg cgacgtgcgc acgccggggt ccatcagacg cagctcaccc
    15901 gcgatcgctg cgcccacctc gtcggtctct ctgctcatac aggcatcttc gtccaggcga
    15961 ccggagcagc cgcaaccggg ttactcacgt cgggctcgga ggccgtccag ggtgaggtcg
    16021 aggaggcgtt cggcctgggc ccgttgttcg gggccggccg aggtgagggc gatgccggcg
    16081 agggcggcga acatgtcggt cgaggtgatg tcggacctga tcgcatccgc ggcggtgcag
    16141 gcctccatca gggaggtgag cgcgtcctgg atcaaccggc ggctgtcggc gtaggggttg
    16201 gtccccgccg cgaggacggc gcgcatcgcg tcggccatgc ccatcttggc tgtggcgtag
    16261 tcgatgaagc ggcgcgtcca gtcgcgcagg gcctcgtacg gcggcatggc cgccaggagg
    16321 gtggggacgg agtcgcacag gcgggcgacc tcgttccggt aggccgcctc gatcagggct
    16381 tcgcgggtgg ggaagttgcg gtagagggtg ccggttccca cgccggcctc cttggcgatg
    16441 cgctcgaagt gcgcctccag gccctgctcg gtgaacacgc gcaccgcggc agccaggatc
    16501 ttgtcccggt tgcgctgtgc gtcggccctc agcgggcgtt ctgcgtctgc ggccatcaac
    16561 ggccctcccc tgcttcctca tcgacacccg cttgctaagt ggaggggcct ccacttagcc
    16621 tggctgaagt ggcggcgcct ccactttcac tctagggcat ggcctcggcc tgccccattc
    16681 ctcttcggaa gggactcccg ccatgtcggg aatcgaaggc aaaatcgtgg ccgtcaccgg
    16741 cgcgggcagc ggcatcggcg aggccaccgc cctcctgctc gccgagcggg gcgcgaaggt
    16801 ggtcctcggc gcacgccgca cggagcgcct ggaggctctg gccgcccgga tcgagaaggc
    16861 cggcggcgag gccgcctgga tccgtacgga cgtgacgcgg cgcaccgacc tggtgggcct
    16921 cgtcgacctg gcgcgagagc ggtacggcag gctcgacgtg ctcgtcggca atgccggggt
    16981 cggattgatc tccccgctcg acgaactgcg cgtcgacgac tgggaggaga tgatcgacgt
    17041 caacttgaag ggcgtcctct acgggatcgc cgcggcgctc cccgtcttcc gggaacaggg
    17101 ctccggccac ttcgtcaacg tcgtgtccac cgccggactg cgggtcgtgc cgctccagtc
    17161 cgtgtacgcg ggcaccaaga acgccgtgcg cacgatctcc gagggcctgc gccaggaggc
    17221 cggggacagc ctgcgcgtga ccgtcgtgtc gcccggcgcc gtccgtacgg acttcacgga
    17281 gcgcatggga ccggaggccc gggaccggat cgaccgcatg atggagaccg cgctgtcgcc
    17341 ggacgcggtg gcccgcgcca tcgccttcgc catcgagcag ccggacggtg tcgacgtggg
    17401 tgacatcgtc gttcgcccca cagcacaggc ctgacggcgg acggcgaacg gaaaaccgcc
    17461 gggggaccgg cacagcgccg gcggcggtgt gccggtcccc cgcgcgccgc tgcctacggg
    17521 gccatctcgt acgtgccgga cagcgcctcg acccgggccc agacgcgcgc cgcgcgcgcc
    17581 tcgtccacga ccggacgccg gaccgcgccg agcgcccagt cctgctgggc agcggtggcc
    17641 gagtccttgc cgtacagctc gacggcgtgg ccggagaagt cgcgcacgag cacggagaac
    17701 agctcgtcga gcacggactc gtccaggtcc gtcaggcggg cctgctccag gaccagctgc
    17761 ccgtagacga ccagcgcgaa cagctggccc acggagagga ggaagtcgag gtcacggctc
    17821 tgctcctcgt ccggcgcgac ggtggccacg aacgcgcaga gggcgtcggc ctgctcgcgg
    17881 aaccgcgcca cgttcggcac ggcggcgtac gcgtcgtagg cggtccgcca gtcgtggaag
    17941 cgtacggagc ccaggccccg ggccggtccc tgctggaaca ggaaggcgtc gtcggccgcg
    18001 tcgagacggg tgggcacctc ggggtactcg gccgggttca gcaggtggtt gtgcatgaac
    18061 ttgaggatca gggccaggtt gacgtggacc gtgccctcca gcttggggag gccgcggatc
    18121 tcgatggccg cctgcgcgaa gtagttgtcc ttctcgaagc ccttggcggc gatgacgtcc
    18181 cacatcaggt cgatgacctt ctcgccctcg gtggtcacct tcatcttcgt catcgggttg
    18241 aagagcaggt aacggcggtc gtccgggccg gcggtgcgga agtagtcgac ggcgcggtcg
    18301 ctgaagagct tcatgccgac caggcggacg tacgcgtcgg ccagctcccg gcgcacgtgc
    18361 gggaaggcgg tgacggggcg gccgtacagg acgcggttgt gcgcgtgggt gacggcctcg
    18421 tacatcgcgt gctcgcagat gccgatggag gcggtgcaga ggttgaactt gccgacgttg
    18481 acagtgttca gggcggcgtc gaaggcggcc cggccggtgt gcaggacgtc ctcggcgcgg
    18541 accgggtagt cgtcgaggcg gaactcgctg acgtacttgg aggagtcgac gacgttcttc
    18601 acgaggtggt acgccgcgtg gcggctgtcg gcggcgaaga agacgtagcc gtcggggccc
    18661 tcgatgtcgg tgcggcggcc gaagaccgag acgaggccgg cggcgttgcc gttgccgatg
    18721 tagtacttgg agccgctcgc gcggaatccg ccggcaccgt cgctgtcggg ctgcagcagc
    18781 atgtcggtgg agtagatgtc ggcgccgtgg ctcttctcgg agaggccgaa ggcgaacacc
    18841 tcgccctcgg agaggagttg cgcggcgcgc tcgcgggcct cggcgttgtc gctctgccag
    18901 accgggccca ggccgaggat ggtgacctgc caggcgtacc agtagtcgag gccgtagaag
    18961 ccgaagatct cgttcagggc cgcgatccgg gcggtgtccc agcgcttgtc cgactccccc
    19021 tcgcccgcgg cggcggccgg ggtcaggaag gtcgcgaaga gcccctcctt cgcggagaac
    19081 gcgaggaagt ccgccagcca cgcgcgggag cggtagtcct cgatcagccg gcgcttgccg
    19141 cggctctcga accagtcgac ggtggcgcgc agcagcctgc gggtctcggg gtcgaagtgc
    19201 gccgggtcgt aggtgtgcgg gttgaagagc agggcgtctg ccatggaggt tcaccttccg
    19261 aggggttggg gtcgggcgcg tggaggggcg cggcggcggg tgcggcggcg cgcacggcgg
    19321 tgcggccgtg cggttcaggc ggtggcggcg gtggtggcag tggtggcagt ggtggcggcg
    19381 gtcgatgcgg tcccgccgag ccggtgcagc gtggcgagga cgtcgtcgag ccaggcgatc
    19441 gtcatccgct cgtacgcgat gccgccgcgc agcacgacgt gctggagctc ctgaccggcg
    19501 tcgagcggcg cgggggcgtc cggcccggtg aagtcgcgca gttcaccggc gagatagcgg
    19561 gccagccggt cgctgtgcgc ccggtggtgc cgctcgacct cctggatgag cgcggccggg
    19621 tcgtcgaagg ccacgccgcg gatcttgacg gcgaggtcgt ggcgcaggct ctcgggttcg
    19681 atcggctcgt gcagccaccc ggcgagtgcg gcgcggccgg gaccggcgac ggagtactcc
    19741 ttcttgtccg gccggccctg ctgcggcacc tcgcggacgg cgagcagccc gtcgccctcc
    19801 atccgcccca gcacgcggta gatctgctgg tgggtggcgg tccagaagta gccgatggac
    19861 cggtcgaacc ggcgggccag ctcgtagccg gagcccggct tctccagcag ggagacgagg
    19921 atcgcgtggt cgagcgccat gccccgatct ttctatgcaa ctcgttgcat agacaagcgg
    19981 cagtgctcag gtgagacgcg gctcacccgg cctcgtcgct gttcgaggag taggcctacc
    20041 gggtgcatcg gggaaccacg gggccctcgc gggcgttggt gcgaccatag ggaaggtgat
    20101 cagccggtcc caccggccgg ctggcccccg ccgctacccg cgccttccga tgactccgag
    20161 gggagccgtt catgagtacg gcgaaagacc tgttcatcat cgcgatggac ccgccgccgg
    20221 accgtcccgt cgggcagggc gacctgtcgc tcgccctcgc cggagccgag ctgatcgacc
    20281 tcctcgacgc gcaggccgcc gccctggacg gcgaccgcat cgtgcccggc gagccgtcgg
    20341 agctgcacga cccgctgctg tccgaggccg cgtcggcgct cacccgccac actccgtacg
    20401 agcgggtcga cgaatggctg tggcgccgcg gccgcgatct gtccgcggcg taccaggccg
    20461 ccctggagga ggccggtgag ctgacgcggg gacggcgcgg cctgctgccc ttcgggagcg
    20521 accgcatgga ggtggccgat acgcccgccc gccggcgggc gctgggccgt caggaggagg
    20581 acgagcccgt cctcgccgcc ctcgcctcgg tcgtgggcct ccgcagcgac gaccccgagg
    20641 ccgaaccccg cccgggcgac gaggcggtga cgaccgtcct ggccgtcgtc aacgacgcgg
    20701 tgatggaact ggaggccgtg cgccagcggc ggaccatcga gaacgcggcg tacgccaaca
    20761 tgtggcgcag cccctgaggc ccgagcgcgg cccggccggc ccggtccgtg tgacggaggc
    20821 tcagccgcgg tcggcggccg tccaccacac tgggtacggg gtgctgccga gcgcggcgtc
    20881 gagggagaag gggtgtgcgg ccggccgggc ggtgtcagcc ggtgtcgagg acgaggtcgg
    20941 cgcggtgccg gccgagggcg acgagccggg cgttggcctc gtccgagcgg gccacccagg
    21001 cacgcgcgtg cgcggggtcc ttgccgtgcc gcacatgacg gtcgatcagc cggtccaggc
    21061 gcaggtcctc ggcgggggcg aggtaccaga cctcgtccag cagcggccgc accgcggacc
    21121 actcccccgc gtcgtgcagc aggtagttcc cctcggtgat caccagcggt acgtccgggg
    21181 cgacggggat gctgcccgcg atcggctcct ccagggagcg gtcgaaggca ggcgcgtaca
    21241 ccgtgggccc ctgcggtgcg cgcagccgcc gcagcagggc gacgtagccg gcggcgtcga
    21301 aggtgtccgg ggcgcccttg cggtcggcgc ggcccaggtc gtccagcacg gcctgcgcga
    21361 ggtggaag
//
