LOCUS       NZ_CP020555            10375 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. Sge12 chromosome, complete genome.
ACCESSION   NZ_CP020555
VERSION     NZ_CP020555.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. Sge12
  ORGANISM  Streptomyces sp. Sge12
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7983613)
  AUTHORS   Tao,M., Xu,J., Xu,M., Liu,K., Zhao,Z. and Peng,Q.
  TITLE     Genome sequence of Streptomyces sp. Sge12, producing unknown
            compounds against rice blast disease
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7983613)
  AUTHORS   Tao,M., Xu,J., Xu,M., Liu,K., Zhao,Z. and Peng,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, Huashan Road 1954, Shanghai 200030,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: RS_HGAP Assembly v. 3; BWA v. 0.7.10; Bowtie v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 85.0x
            Sequencing Technology :: Illumina HiSeq 4000; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:12:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,312
            CDSs (total)                      :: 7,216
            Genes (coding)                    :: 7,106
            CDSs (with protein)               :: 7,106
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 32 of 111
            Pseudo Genes (incomplete)         :: 91 of 111
            Pseudo Genes (internal stop)      :: 8 of 111
            Pseudo Genes (multiple problems)  :: 18 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:35:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 112191
            Orig. end                         :: 122566
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020555.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10375
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="2"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10375
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10375
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5375](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5375)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     gene            136..726
                     /locus_tag="B6R96_RS00530"
                     /old_locus_tag="B6R96_00535"
     CDS             136..726
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321958.1"
                     /locus_tag="B6R96_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00535"
                     /product="hypothetical protein"
                     /protein_id="WP_107084824.1"
                     /transl_table=11
                     /translation="MSALPVNRLSPSAVTDLSDLLATCFQQDALTRWMIPGEQRRAELL
                     PGFFRVFVELSAAFDGVLTSPDGDAVLLFLPPGAEPDEKALDAAFADVLGEYADAMRTI
                     AGLQEEAHPHGAPHYYVSFGAVRPGRQQSGLMSALLGRVAARADAEGVGAYVEASSPGG
                     EATSRRVGFGLLGTDIALPGGGPVLRPMWRDPR"
     gene            723..1358
                     /locus_tag="B6R96_RS00535"
                     /old_locus_tag="B6R96_00540"
     CDS             723..1358
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105932.1"
                     /locus_tag="B6R96_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00540"
                     /product="DUF6875 domain-containing protein"
                     /protein_id="WP_030390281.1"
                     /transl_table=11
                     /translation="MRGDDLIQSWTAGEIARGEAPAEHLGPLLQVLMWSREFLVSSHPE
                     LGRTGPVCPYTQPSLRKELFHLAVPAAGCEDLASAVDSLRTRHAVLSQRLTPEDRELLT
                     ILLVLPGFDPTDSVELDELQRKAKDEFVAEGLMIGQFHPVCEEPGLYNEAFRPLRSPVP
                     LLAVRKLLVFDLPFLVGDDAHMDHYLQRFAPDLPSRIRDQLVSRVVAV"
     gene            complement(1463..2338)
                     /locus_tag="B6R96_RS00540"
                     /old_locus_tag="B6R96_00545"
     CDS             complement(1463..2338)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (44-135). E-value:
                     6.2e-10. Score: 31.0. Matches aSDomain:
                     nrpspksdomains_B6R96_RS00540_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523330.1"
                     /locus_tag="B6R96_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00545"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_081521157.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 8.2e-12, bitscore:
                     44.9, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 8.6e-05, bitscore: 21.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTQTTTQVTTQHPTPRPHTLNAGGITLSALLSLPPDGTPVRST
                     ILAIHGRGMRAAYWNSFAPLATALGHAVLAVDRPGYGDSTDQLPDGQSLAEQAETLHAA
                     LKEHAAEYDIGAGILLLGHSDGGKVALHTAAADGGGTPLLGLDASGVGHHYNPRALHFP
                     STLGAGATKLNWGPLNLYPQGTFRASRTLLAPTPPRESAETLRWPGQYEALAPHVRIPV
                     RLTFAEHEAWWHLDAPTLTAMTSRLTAAPSVTVDHLAASGHNISLGHTAPAYHLRVLTF
                     LEDCLRTAPH"
     aSDomain        complement(1934..2206)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B6R96_RS00540_Abhydrolase_1.1"
                     /evalue="6.20E-10"
                     /label="B6R96_RS00540_Abhydrolase_1.1"
                     /locus_tag="B6R96_RS00540"
                     /protein_end="135"
                     /protein_start="44"
                     /score="31.0"
                     /tool="antismash"
                     /translation="TILAIHGRGMRAAYWNSFAPLATALGHAVLAVDRPGYGDSTDQLP
                     DGQSLAEQAETLHAALKEHAAEYDIGAGILLLGHSDGGKVALHTAA"
     gene            complement(2335..3057)
                     /locus_tag="B6R96_RS00545"
                     /old_locus_tag="B6R96_00550"
     CDS             complement(2335..3057)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321952.1"
                     /locus_tag="B6R96_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00550"
                     /product="indole-3-glycerol phosphate synthase"
                     /protein_id="WP_081521158.1"
                     /transl_table=11
                     /translation="MTKDNRTAFPFLEALLTSPTPVVMEVKRRDAHGYDMLGGRTPAAI
                     VAAYESAGAPCVSVVTGRWFGGSPALLRDVAALTALPILQKDFITRKDQIRTAKELGAS
                     AVLLTAALLPASSMRTLVTECLLSGLTPFVEITQESELASVHHPEDCVIAVNNKDIKTR
                     ERGAGDLGRSLDLLPAVTATGAACPVSASGIDSPQNAAALLDAGFGGLLVGTSLLRTGS
                     PAAWVDAMAGTRKGLALR"
     gene            complement(3054..3806)
                     /locus_tag="B6R96_RS00550"
                     /old_locus_tag="B6R96_00555"
     CDS             complement(3054..3806)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105934.1"
                     /locus_tag="B6R96_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00555"
                     /product="N-(5'-phosphoribosyl)anthranilate isomerase"
                     /protein_id="WP_257789481.1"
                     /transl_table=11
                     /translation="MSTTRPLSRTLLKVCGATTPQDIEAAAAAGADCVGLWHGVPGGPS
                     ELDRNGLAALAAAARSTGLLPVLVTFLSDAGELAAIAAHTGIGWIQLHAYQPPALVRAL
                     RQALPADVGIVKVLHVQENGGCVERPLIGAYDRAGTDLFLLDTATGDGRIGSTGAALDP
                     DRVTALLPRLTRPFLLAGGLTPTNRPAYEDVVHHPGFRGIDVDTAARTTTGGFGVPQIA
                     ALARAWRTDTHHTHHTPRPDHPRLELSR"
     gene            complement(3803..4948)
                     /locus_tag="B6R96_RS00555"
                     /old_locus_tag="B6R96_00560"
     CDS             complement(3803..4948)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105935.1"
                     /locus_tag="B6R96_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00560"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_081521159.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2e-16, bitscore:
                     59.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.7e-25, bitscore:
                     87.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.9e-29, bitscore:
                     100.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRWNADQAELRDGLERWGDALSADHIELDEQSAFSEDKWKLVQK
                     TGILSLPFDEDHGGLGQSLLTTMYVLEGLGEYNRDAGLSFCITTSICSTGIPLQHFGTT
                     EQKDRYLHRICSGEAIGAHAITEAEGGSDAMAMATRAVRDGDDFVINGSKVFVSNGPIA
                     DVIVVYARTHPDGGPLGTTAFLVDRNTPGLSAGKPIKKMGLRTSPLSELFFDDVRVPKT
                     AVLGRVGGGFLVLDHVMKREILFSFIVNVGEMQHRLERCVEYARTRKSFGKAIGSYQTI
                     ANKIVDTKIQLETARKWLYDTGEKLEAGENVTTDLAISKIVTSESNLATSLTAVQIFGG
                     HGYMAEFGLEQDVRNAVGGTIYSGTNEIQYNRIASMLGLGK"
     gene            complement(5001..5375)
                     /locus_tag="B6R96_RS00560"
                     /old_locus_tag="B6R96_00565"
     CDS             complement(5001..5375)
                     /GO_function="GO:0033990 - ectoine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105936.1"
                     /locus_tag="B6R96_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00565"
                     /product="ectoine synthase"
                     /protein_id="WP_030390275.1"
                     /sec_met_domain="ectoine_synt (E-value: 1.8e-31, bitscore:
                     107.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRDIESVKTVEWGNGLSRRFLLAEDGLGYSLTDTTVLAGTKSR
                     LEYVNHLEACYCIEGSGEVIELDGTSHEIVPGRMYALDQHDAHYLVASPHEDLRLVCVF
                     SPALRGDEVHSLDAHSSSAY"
     misc_feature    5425..5439
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.05"
                     /tool="antismash"
     gene            complement(5446..6327)
                     /gene="trpA"
                     /locus_tag="B6R96_RS00565"
                     /old_locus_tag="B6R96_00570"
     CDS             complement(5446..6327)
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321768.1"
                     /locus_tag="B6R96_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00570"
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="WP_081521160.1"
                     /transl_table=11
                     /translation="MPSPTAPAPTAGTDTAPTTTPAPAPFFTRRTPDGPPALALFLNAG
                     DPPLPVLRDLVLMLDEEGVACLELAVPFPDSVTDGPVIRRSARRALQAGGADLDDVLAF
                     IADVRPHLKHLRIALLADWSHSLKHRDLATTTREIAAAGADGLLLHALPPRLRTTHLET
                     AAAAGLPVVTTCYTQSPPATQAQAAAQASAYLYLVAHYGRSGTAPATGHAALAQTVTAL
                     RAHTTSPIAVGFGVSTRQDVQAVGAAGADAAIIGSAAVAAVERALETGTDTVAAFRTFV
                     RQILPEPPHRTA"
     gene            complement(6320..7369)
                     /locus_tag="B6R96_RS00570"
                     /old_locus_tag="B6R96_00575"
     CDS             complement(6320..7369)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321935.1"
                     /locus_tag="B6R96_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00575"
                     /product="hypothetical protein"
                     /protein_id="WP_081521161.1"
                     /transl_table=11
                     /translation="MHDALTGLLEQRAPVGRETWRSWWDQLGDGGLDQAQVVALLASLT
                     SRLPDHQTLRHLLDSLAERRPAAPATTTAWEGTVNVVGTGGGPRTFNISTASAFVAAAA
                     GVKVVKTGSRAYTSSLGSVDLLERLGVRLTSSHAQTEDTLATHGIAFAGPFVYPTQLTR
                     LARTVAPHSMKPFGRFLNALGPFLADLPVTAQVTGVSAAAPLDTLRHLARTTTTRRIWL
                     TSNDTGADELLPFATNTIHGENSLTRIIRPGELTPGDGSFADLRPATDPTAAVAHFLTV
                     LAGDAGRVATRTVCLGAAALVVASGTRRDWLSAVSVAEDAIRSGAAHALAQRLATAPAP
                     TRTLAVTGA"
     gene            complement(7423..7680)
                     /locus_tag="B6R96_RS00575"
                     /old_locus_tag="B6R96_00580"
     CDS             complement(7423..7680)
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (18-62). E-value: 1.6e-07.
                     Score: 23.5. Matches aSDomain:
                     nrpspksdomains_B6R96_RS00575_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147: putative acyl carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321933.1"
                     /locus_tag="B6R96_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00580"
                     /product="acyl carrier protein"
                     /protein_id="WP_030390272.1"
                     /sec_met_domain="PP-binding (E-value: 1.9e-05, bitscore:
                     23.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 0.0039, bitscore:
                     16.1, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNIDTIKNFVITEFLPGTTPAELATDHDLLNDGVIDSLGVLKLI
                     AWVEDRFELAIGDADLDPNNFRSVEAIDTFITASRRTAAA"
     aSDomain        complement(7495..7626)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B6R96_RS00575_PP-binding.1"
                     /evalue="1.60E-07"
                     /label="B6R96_RS00575_PP-binding.1"
                     /locus_tag="B6R96_RS00575"
                     /protein_end="62"
                     /protein_start="18"
                     /score="23.5"
                     /tool="antismash"
                     /translation="TTPAELATDHDLLNDGVIDSLGVLKLIAWVEDRFELAIGDADLD"
     gene            complement(7677..9302)
                     /locus_tag="B6R96_RS00580"
                     /old_locus_tag="B6R96_00585"
     CDS             complement(7677..9302)
                     /NRPS_PKS="Domain: AMP-binding (28-417). E-value: 8.3e-73.
                     Score: 237.2. Matches aSDomain:
                     nrpspksdomains_B6R96_RS00580_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105940.1"
                     /locus_tag="B6R96_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00585"
                     /product="AMP-binding protein"
                     /protein_id="WP_081521162.1"
                     /sec_met_domain="AMP-binding (E-value: 7.4e-75, bitscore:
                     250.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPRTPRTTPAAPGRTAPTVELGLLGGFLTQVRDRPHATALLFN
                     GQETTYRELYELAGRERDRLAHLDLAPGEPVGILADKSPAALALVLACLLARRPLLLPS
                     PALADTLLADLFAQAGCATVLAPDGQSARVTPNPEVTARPLPAAEAAEVAFMLTTSGST
                     SLPKIVPLGLDAVDRFTRWAGHTFQITAGRTVLNYAPLNFDLCLLDVWTTLARGGRVVL
                     VDPALAAHGRHLRDLVLHHKVDIVQAVPMAFGLLQDAAAKTGDTFPGVEHVMFTGDAIP
                     ERTLAALPQLFPHARIHNIYGCTETNDSFIHEVDTAPAAHPTTPVPIGRPLPGVRALII
                     DPDTHTPVQGAGSGELFVSTPFQTRGYLDRTRHTDKFTGHPLGLDDRRWFRTGDLVRRD
                     DAGTLHLTGRTDFQVKVRGVAVNTAEIERILQEHPDVLEAGVAALPDPIAGKRLVAAVQ
                     RAPGTTLTGLQLRTHCARHLPRAAVPHQLTVTEQPLPKTATGKVDRKQLDRLDRPAPTT
                     GSTTGTTRSTPAPVATPLAEGIPS"
     CDS_motif       complement(8022..8084)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B6R96_RS00580_0003"
                     /evalue="7.90E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="B6R96_RS00580"
                     /protein_end="427"
                     /protein_start="406"
                     /score="21.6"
                     /tool="antismash"
                     /translation="TGRTDFQVKVRGVAVNTAEIE"
     aSDomain        complement(8052..9218)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B6R96_RS00580_AMP-binding.1"
                     /evalue="8.30E-73"
                     /label="B6R96_RS00580_AMP-binding.1"
                     /locus_tag="B6R96_RS00580"
                     /protein_end="417"
                     /protein_start="28"
                     /score="237.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FLTQVRDRPHATALLFNGQETTYRELYELAGRERDRLAHLDLAPG
                     EPVGILADKSPAALALVLACLLARRPLLLPSPALADTLLADLFAQAGCATVLAPDGQSA
                     RVTPNPEVTARPLPAAEAAEVAFMLTTSGSTSLPKIVPLGLDAVDRFTRWAGHTFQITA
                     GRTVLNYAPLNFDLCLLDVWTTLARGGRVVLVDPALAAHGRHLRDLVLHHKVDIVQAVP
                     MAFGLLQDAAAKTGDTFPGVEHVMFTGDAIPERTLAALPQLFPHARIHNIYGCTETNDS
                     FIHEVDTAPAAHPTTPVPIGRPLPGVRALIIDPDTHTPVQGAGSGELFVSTPFQTRGYL
                     DRTRHTDKFTGHPLGLDDRRWFRTGDLVRRDDAGTLHLTGRTDFQVKVR"
     CDS_motif       complement(8178..8243)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B6R96_RS00580_0002"
                     /evalue="1.80E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="B6R96_RS00580"
                     /protein_end="375"
                     /protein_start="353"
                     /score="10.8"
                     /tool="antismash"
                     /translation="GELFVSTPFQTRGYLDRTRHTD"
     CDS_motif       complement(8793..8843)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B6R96_RS00580_0001"
                     /evalue="4.00E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="B6R96_RS00580"
                     /protein_end="170"
                     /protein_start="153"
                     /score="10.4"
                     /tool="antismash"
                     /translation="AFMLTTSGSTSLPKIVP"
     gene            complement(9299..10147)
                     /locus_tag="B6R96_RS00585"
                     /old_locus_tag="B6R96_00590"
     CDS             complement(9299..10147)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105941.1"
                     /locus_tag="B6R96_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6R96_00590"
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="WP_051779855.1"
                     /transl_table=11
                     /translation="MTTLSLPSPVRTLTVTEPEITDYRGAARRSLPTARPGQASPVHTF
                     VLAHTVAEQTVAALTAAEPGPVSVVHLGQDIRTLRPVRPGEQVTVTLDVLGIRKEARGA
                     RIALHIRLTGEDGPDPFAELVISALLVGATLLEPFGDISGGPAAPAPLGTGEPQSAVHA
                     LTTDWITTYAHASGDLNPIHLDEDAARAAGFDTVIAHGMSVVALAVEEATDRFAAGDSA
                     RVRGLGCRFSAPVPPGIPLEITLQPDAEARVVRFTCKTPKGAAVKSGWIEFADPAPGGP
                     R"
ORIGIN
        1 gcggccgacg cccgggccac accctgaccc cgctcccccg ctcccccgct cccccgttgc
       61 ttcttctgcc ttgcttcttc cgccgttccc tgttccgccg ttcctccatc ccgtcacctg
      121 accggaggcc ttgccttgtc tgccctgccc gtgaaccggc tgagcccatc ggccgtcacc
      181 gatctgtccg accttctcgc cacctgcttc cagcaggacg ccctgacccg ctggatgatc
      241 cccggcgagc agcggcgcgc cgagctgctg cccgggttct tccgggtgtt cgtggaactg
      301 tccgccgcct tcgacggggt gctcaccagc ccggacggcg acgcggtgct gctgttcctg
      361 ccgcccggcg ccgagccgga cgagaaggcc ctggacgcgg cgttcgccga tgtcctgggc
      421 gagtacgcgg atgcgatgcg caccatcgcg ggcctccagg aggaggccca tccgcacggc
      481 gcgccgcact actacgtctc cttcggggcg gtgcgccccg gccggcagca gagcgggctg
      541 atgtccgccc tgctgggccg ggtggcggcc cgtgcggacg ccgagggggt cggcgcctat
      601 gtggaggcca gctcccccgg cggtgaggcc accagccggc gtgtcggttt cggactgctg
      661 ggcacggaca tcgcgctgcc cggcggagga cctgtactgc gacccatgtg gagggacccc
      721 cgatgagggg agacgatctg atccagtcgt ggaccgccgg cgagatagcc cgcggtgagg
      781 ctcctgcgga gcacctcggg ccgttgctcc aggtgctgat gtggagccgg gagttcctgg
      841 tctccagcca tcccgagctg gggcgcaccg gtccggtgtg cccgtacacg cagccctcgc
      901 tgcgcaagga gctgttccat ctggcggtgc cggcggcggg gtgcgaggac ctggcctcgg
      961 cggtggactc gctgcgtacc cgtcatgcgg tgctgtcgca gcggctgacg ccggaggacc
     1021 gtgagctgtt gacgatcctg ctggtgctgc cggggttcga tccgacggat tcggtggagc
     1081 tggacgagtt gcagcgcaag gcgaaggacg agttcgtggc ggaggggctg atgatcggtc
     1141 agttccatcc ggtgtgcgag gagccgggcc tgtacaacga ggcgttcagg ccgctgcgct
     1201 ctccggtgcc gttgctggcg gtgcgcaagc tgctggtgtt cgatctgccg ttcctggtgg
     1261 gcgacgacgc gcacatggac cactatttgc agcgtttcgc gccggatctg ccgtcgcgga
     1321 tccgtgacca gttggtgagc cgggtggtgg ccgtctgagg cggccggtgc acggctgtgg
     1381 ccccggtggc gtctgccacc ggggcctcgg tctgtcgggc ggtcggtcgg gcggtctgtg
     1441 gggcgggtgg ggcgggggcg gctcagtgcg gggcggtgcg caggcagtcc tcgaggaagg
     1501 tcaggacgcg caggtggtag gcgggggcgg tgtggccgag gctgatgttg tggccggagg
     1561 cggccaggtg gtcgacggtg acgctggggg cggccgtcag gcgggaggtc atcgcggtga
     1621 gggtgggggc gtccaggtgc caccaggcct cgtgttcggc gaaggtgagg cggacgggga
     1681 tgcggacgtg cggggccagg gcttcgtact ggccgggcca gcgcagggtt tccgcggact
     1741 cgcgcggtgg tgtgggggcg agcagggtgc ggctggcccg gaaggtgcct tgcgggtaga
     1801 ggttcagggg gccccagttg agtttggtgg cgccggcgcc cagggtggag gggaagtgca
     1861 gggcccgggg gttgtagtgg tggccgacgc cggaggcgtc caggcccagc aggggggtgc
     1921 cgccgccgtc ggcggccgcg gtgtggaggg cgaccttgcc gccgtcggag tggcccagca
     1981 ggaggatccc ggcgccgatg tcgtactcgg cggcgtgttc cttgagggcg gcgtggaggg
     2041 tttcggcctg ctcggcgagg ctctggccgt cgggcagctg gtcggtggag tcgccgtagc
     2101 cggggcggtc gacggccagg acggcgtggc ccagggcggt ggcgaggggg gcgaaggagt
     2161 tccagtaggc ggcgcgcatg ccgcggccgt ggatggccag gatcgtggag cggaccggtg
     2221 tgccgtcggg gggcaggctc aggagggcgg agagggtgat gccgcccgcg ttgagggtgt
     2281 ggggccgggg ggtggggtgc tgggtcgtca cctgtgtcgt cgtctgtgtc gtcgtcatcg
     2341 cagggccagc cccttccggg tgcccgccat ggcgtccacc caggccgcgg gcgatccggt
     2401 gcgcagcagt gaggtgccca cgaggaggcc gccgaagccg gcgtccagga gtgcggcggc
     2461 gttctggggg ctgtcgatgc cgctggcgct gacggggcag gcggcgccgg tggcggtgac
     2521 ggcgggcagc aggtccaggg agcggccgag gtctccggcg ccgcgttcgc gggtcttgat
     2581 gtccttgttg ttgacggcga tgacgcagtc ctcggggtgg tggaccgagg cgagttcgct
     2641 ttcctgggtg atctcgacga agggggtgag gccggagagc aggcattcgg tgaccagggt
     2701 ccgcatgctc gacgccggca gcagtgccgc ggtgagcagg actgcggagg cgccgagctc
     2761 cttggcggtg cggatctggt ccttgcgggt gatgaagtcc ttctggagga tcggcagtgc
     2821 ggtcagtgcg gccacgtcgc gcagcagggc gggtgagccg ccgaaccagc ggcccgtgac
     2881 gaccgagacg cagggtgcgc ccgcgctctc gtaggcggcg acgatggcgg cgggggttct
     2941 gccgccgagc atgtcgtagc cgtgggcgtc gcgtcgtttc acctccatca ccacgggggt
     3001 cggggaggtc aggagggcct cgagaaaagg gaaggcggtc cggttgtcct tcgtcatcgc
     3061 gacagctcca gtcgggggtg gtcggggcgg ggggtgtggt gggtgtggtg ggtgtcggtg
     3121 cgccaggcgc gggccagggc ggcgatctgc gggacgccga agccgccggt ggtggtgcgg
     3181 gcggcggtgt cgacgtcgat gccgcggaat ccggggtggt ggacgacgtc ctcgtaggcg
     3241 ggtcggttgg tgggggtcag gccgccggcg aggaggaagg ggcgggtcag gcggggcagc
     3301 agggcggtga cgcggtcggg gtccagggcg gcgccggtgc tgccgatgcg gccgtcgccg
     3361 gtggcggtgt cgaggaggaa gaggtcggtg ccggcccggt cgtaggcgcc gatcaggggg
     3421 cgttccacgc agccgccgtt ctcctggacg tgcagcacct tgacgatgcc gacgtcggcg
     3481 gggagtgcct ggcgcagggc ccggacgagg gcggggggct ggtaggcgtg gagttggatc
     3541 cagccgatgc cggtgtgcgc cgcgatcgcg gcgagttcac cggcgtcgga caggaacgtc
     3601 accaggaccg gcaggaggcc ggtggagcgg gccgccgccg cgagggcggc gagcccgttc
     3661 cggtccagtt cgctggggcc gccgggtacg ccgtgccaga ggccgacgca gtcggccccg
     3721 gcggccgccg cggcctcgat gtcctgcggg gtggtggctc cgcagacctt cagcagggtc
     3781 cgggacaggg ggcgggtggt gctcacttgc ccagtcccag catcgaggcg atgcggttgt
     3841 actggatttc gttggtgccg gagtagatcg tgccgccgac cgcgttgcgc acgtcctgct
     3901 ccaggccgaa ctcggccatg tagccgtggc cgccgaagat ctgtacggcg gtgaggctgg
     3961 tggcgaggtt ggactcgctg gtgacgattt tggagatggc gaggtcggtg gtgacgttct
     4021 cgccggcctc cagtttttcg ccggtgtcgt agagccactt gcgggcggtc tccagctgga
     4081 tcttcgtgtc gacgatcttg ttggcgatcg tctggtacga accgatcgcc tttccgaacg
     4141 acttgcgtgt cctggcgtat tcgacgcagc gttccagccg gtgctgcatc tcccccacgt
     4201 tgacgatgaa ggagaagagg atttcccgtt tcatcacgtg gtccaggacc aggaagcctc
     4261 ctccgacgcg gccgaggacc gcggttttcg gtacccgtac gtcgtcgaag aacagctcgc
     4321 tgagcggtga ggtgcgcagg cccatcttct tgatgggttt gccggcgctc aggccggggg
     4381 tgttgcggtc gacgaggaag gcggtggtgc cgagcgggcc gccgtccggg tgggtgcggg
     4441 cgtagacgac gatcacgtcg gcgatggggc cgttgctgac gaagaccttg ctgccgttga
     4501 tgacgaagtc gtcgccgtcg cgtacggccc tggtggccat ggccatggcg tcggagccgc
     4561 cttcggcctc ggtgatggcg tgggcgccga tcgcctcgcc cgagcagatg cggtgcaggt
     4621 agcggtcctt ctgctcggtg gtgccgaagt gctggagggg gatgccggtg gagcagatgg
     4681 aggtggtgat gcagaagctg aggcccgcgt cgcggttgta ctcgccgagg ccctccagta
     4741 cgtacatggt ggtcaggagt gactgtccga ggcctccgtg gtcctcgtcg aagggcagtg
     4801 agaggatgcc ggtcttctgg acgagcttcc acttgtcctc ggagaaggcg gactgctcgt
     4861 cgagttcgat gtggtctgcg ctgagtgcgt ctccccaccg ctccaggccg tcgcgcagtt
     4921 ctgcctggtc ggcgttccaa cggatcacga gggacccctt tgattcggtg atggtgagga
     4981 tgggtgctgc atcgggtgcc tcagtaggcg gaggagctgt gggcgtctag gctgtggacc
     5041 tcgtcgccgc gcagggcggg tgagaagacg cagaccaggc gcaggtcctc gtgcgggctg
     5101 gcgacgaggt agtgggcgtc gtgctggtcg agtgcgtaca tgcggcccgg gacgatctcg
     5161 tgggaggtgc cgtcgagttc gatgacctcg ccggagccct cgatgcagta gcaggcctcg
     5221 aggtggttga cgtactccag gcgggacttg gtgccggcca ggacggtggt gtcggtgagc
     5281 gagtagccca ggccgtcctc ggcgaggagg aagcggcggc tgaggccgtt gccccactcg
     5341 acggtcttca cggactcgat gtcgcgaacg atcatggcag tctcctggtg tgagggtggt
     5401 gcacgggatg gttcggatga ggggtggaga tcgtgttccc gccggtcagg cggttcggtg
     5461 cggtggttcg ggcaggatct gccggacgaa ggtgcggaag gcggcgaccg tgtcggtgcc
     5521 ggtttccagg gctcgttcga cggcggcgac cgcggcggag ccgatgatcg cggcgtcggc
     5581 gccggcggcg ccgacggcct ggacgtcctg ccgtgtgctg accccgaagc cgacggcgat
     5641 cggggacgtg gtgtgggccc gtagggcggt gaccgtttgg gccagtgcgg cgtggccggt
     5701 ggcgggtgcg gttccgctgc gtccgtagtg ggcgacgagg tagaggtagg cggaggcctg
     5761 tgcggcggcc tgggcctggg tggcgggcgg gctttgggtg tagcaggtgg tgacgacggg
     5821 caggccggcg gcggcggctg tttccaggtg ggtggtgcgc agccgtgggg gcagggcgtg
     5881 caggaggagt ccgtcggcgc cggcggcggc gatctcgcgg gtggtggtgg ccaggtcccg
     5941 gtgtttgagg gagtggctcc agtcggcgag cagggcgatg cgcaggtgct tcaggtgggg
     6001 ccgtacgtcg gcgatgaagg cgagtacgtc gtccaggtcg gctccgccgg cttgcagtgc
     6061 ccggcgggcg gagcggcgga tgacggggcc gtcggtgacc gagtcgggga aggggacggc
     6121 cagttcgagg caggccacgc cctcttcgtc gagcatgagg accaggtcgc gcaggacggg
     6181 caggggcggg tcgccggcgt tgaggaagag ggcgagtgcg gggggtccgt cgggggtgcg
     6241 gcgggtgaag aagggggcgg gggccggtgt ggtggtcggg gcggtgtccg tccccgccgt
     6301 gggggccggc gctgtggggc taggcaccgg tcaccgccag ggtgcgggtg ggggccgggg
     6361 cggtggcgag gcgttgtgcg agggcgtggg cggcgccgga gcggatggcg tcctcggcga
     6421 cggagacggc cgagagccag tcgcggcggg tgccggaggc cacgaccagg gcggcggcgc
     6481 cgaggcagac ggtgcgggtg gcgacgcggc cggcgtcgcc ggccaggacg gtgaggaagt
     6541 gggcgacggc ggcggtgggg tcggtggccg gccgcaggtc ggcgaaggag ccgtcgccgg
     6601 gggtgagttc gccgggtcgg atgatgcggg tcagggagtt ctcgccgtgg atggtgttgg
     6661 tggcgaaggg caggagttcg tccgcgccgg tgtcgttgga ggtgagccag atgcggcggg
     6721 tggtggtggt ccgggcgagg tggcgcaggg tgtcgagggg ggcggccgcc gagactccgg
     6781 tgacctgggc ggtcaccggg aggtcggcga ggaaggggcc cagggcgttc aggaaccggc
     6841 cgaagggttt catgctgtgg ggggccacgg tccgtgccag ccgggtcagt tgggtggggt
     6901 agacgaacgg gccggcgaag gcgatgccgt gggtggcgag ggtgtcctcg gtctgggcgt
     6961 gggaggaggt gagacggacg ccgagccgct ccagcaggtc gacggagccc agtgagctgg
     7021 tgtaggcgcg ggagccggtt ttgacgacct tgactccggc tgcggcggcg acgaaggccg
     7081 aggcggtgga gatgttgaag gtcctggggc cgccgccggt gccgacgacg ttcacggtgc
     7141 cttcccaggc ggtggtcgtc gcgggggctg ccgggcggcg ctcggcgagc gagtccagca
     7201 ggtggcgcag ggtctggtgg tcggggagcc ggctggtcag ggaggccagc agggcgacga
     7261 cctgggcctg gtccaggccg ccgtcgccga gctggtccca ccaggaccgc caggtctcgc
     7321 ggccgaccgg ggctcgctgt tccagcaggc cggtgagtgc gtcgtgcacg gtcggtctcc
     7381 gtctcgtctg cgtcgggtcg gggtcggtcg gtggtgggcg ggtcaggcgg ccgcggtgcg
     7441 ccgggaggcg gtgatgaagg tgtcgatggc ctcgacgctg cggaagttgt tggggtccag
     7501 gtcggcgtcg ccgatggcga gttcgaagcg gtcctcgacc caggcgatga gcttgaggac
     7561 gcccaggctg tcgatgaccc cgtcgttgag gaggtcgtgg tcggtggcga gttcggcggg
     7621 ggtggtgccc gggaggaact cggtgatgac gaagttcttg atggtgtcga tgttgctcat
     7681 gacgggattc cttcggcgag aggtgtggcg acgggtgcgg gcgtggatcg ggtggtgccg
     7741 gtggtgctgc cggtggtggg ggccggccgg tcgagtcggt cgagttgctt gcggtcgact
     7801 tttccggtgg cggtcttggg caggggctgt tcggtgacgg tgagttggtg cgggacggcg
     7861 gccctgggca ggtggcgggc gcagtgggtg cgcagttgca ggccggtcag ggtggtgccg
     7921 ggggcgcgct ggaccgcggc gaccagtcgt ttgccggcga tggggtcggg cagggccgcg
     7981 acgccggctt ccaggacgtc ggggtgttct tgcaggatcc gttcgatctc ggcggtgttg
     8041 acggcgacgc cgcggacctt gacctggaag tcggtgcgtc cggtcaggtg cagggtgccg
     8101 gcgtcgtcgc gtcgtacgag gtcgccggtg cggaaccagc ggcggtcgtc caggcccagg
     8161 gggtggccgg tgaacttgtc ggtgtggcgg gtgcggtcga ggtagccgcg ggtctggaag
     8221 ggcgtggaga cgaagagttc tccgctgccg gctccctgga cgggggtgtg ggtgtcgggg
     8281 tcgatgatca gggcgcgtac gccgggcagt gggcggccga tggggacggg tgtcgtgggg
     8341 tgggcggccg gtgcggtgtc gacctcgtgg atgaagctgt cgttggtctc ggtgcatccg
     8401 tagatgttgt ggatgcgggc gtgggggaag agctggggca gggcggcgag ggtgcgctcg
     8461 ggtatggcgt cgccggtgaa catgacgtgt tcgacgccgg ggaaggtgtc gccggtcttg
     8521 gcggccgcgt cctggaggag tccgaaggcc atggggacgg cctggacgat gtcgaccttg
     8581 tggtgcagga ccaggtcgcg caggtggcgg ccgtgggcgg ccagggcggg gtcgacgagg
     8641 accacgcgtc cgccgcgggc gagggtggtc cacacgtcga ggaggcagag gtcgaagttg
     8701 aggggggcgt agttcaggac ggtgcggcct gctgtgatct ggaaggtgtg gccggcccag
     8761 cgggtgaacc ggtcgacggc gtccaggccc agcgggacga tcttggggag gctggtggat
     8821 ccggaggtgg tgagcatgaa ggccacttcg gcggcctcgg cggcgggcag cggccgggcg
     8881 gtgacctcgg ggttgggggt gacgcgggcg ctctgcccgt cgggggccag gacggtggcg
     8941 cagccggcct gggcgaagag gtcggccagg agggtgtcgg cgagggccgg ggaggggagc
     9001 agcagggggc gtcgggcgag caggcaggcc aggacgaggg cgagggcggc gggtgacttg
     9061 tcggcgagga tgccgaccgg ttcgccgggg gcgaggtcca ggtgtgcgag ccggtcgcgt
     9121 tcgcggccgg cgagctcgta cagctcgcgg taggtggtct cctggccgtt gaacagcagg
     9181 gcggtggcat gggggcggtc gcggacctgg gtcaggaagc cgccgaggag gccgagttcg
     9241 acggtggggg cggtgcggcc gggggctgcg ggggtggtgc ggggggtgcg gggtgcggtc
     9301 atcgggggcc tcccggtgcg gggtcggcga actcgatcca gccggacttc acggcggccc
     9361 ccttgggggt cttgcaggtg aagcggacga cgcgggcctc ggcgtcgggc tggagggtga
     9421 tctccagcgg gatgccgggg ggtacggggg cggagaagcg gcagcccagg ccgcggacgc
     9481 gggcggagtc gccggcggcg aagcggtcgg tggcctcctc gacggcgagg gcgaccacgc
     9541 tcatgccgtg ggcgatgacg gtgtcgaagc cggcggcgcg ggcggcgtcc tcgtcgaggt
     9601 ggatggggtt gaggtcgccg gaggcgtggg cgtaggtggt gatccagtcg gtggtcaggg
     9661 cgtggaccgc gctctgcggc tcgccggtcc cgagcggggc gggggcggcg gggccgcccg
     9721 agatgtcgcc gaagggctcc aggagggtcg cgccgaccag cagggcggag ataaccagtt
     9781 ccgcgaaggg gtcggggccg tcctcgccgg tcaggcggat gtgcagggcg atgcgggcgc
     9841 cgcgggcctc cttgcggatg ccgaggacgt ccagggtcac ggtgacctgc tcgccggggc
     9901 ggaccgggcg cagggtgcgg atgtcctggc cgaggtggac gacggatacg gggcccggtt
     9961 cggccgcggt cagtgcggcg acggtctgtt cggccacggt gtgggcgagg acgaaggtgt
    10021 ggacggggga tgcctggccg gggcgggcgg tgggcaggga gcggcgggcg gcgccgcggt
    10081 agtcggtgat ctcgggttcg gtgacggtga gcgtgcggac cggggagggc agggagaggg
    10141 tcgtcatacc ggcgtcacca ccacggagga gttgtggccg ccgaatccga aggagttcgt
    10201 gatcgcgggt ccggggcgca cggcgcgggg tgcgccgtgg acgacgtcga tgtccattcc
    10261 tggctcctgc tgttcgtggt tggcggtggg tggcacctcg cagtggtgca tggcctgcac
    10321 ggtggcgatg agttcgacgg cgccggcggc gccgatgagg tggccgatga ccgac
//
