LOCUS       NZ_CP017717            31245 bp    DNA     circular CON 03-MAR-2024
DEFINITION  [Actinomadura] parvosata subsp. kistnae strain ATCC 55076
            chromosome, complete genome.
ACCESSION   NZ_CP017717
VERSION     NZ_CP017717.1
KEYWORDS    RefSeq.
SOURCE      [Actinomadura] parvosata subsp. kistnae
  ORGANISM  [Actinomadura] parvosata subsp. kistnae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 13047416)
  AUTHORS   Nazari,B., Forneris,C.C., Gibson,M.I., Moon,K., Schramma,K.R. and
            Setedsayamdost,M.R.
  TITLE     Nonomuraea sp. ATCC 55076 harbors the largest actinomycete
            chromosome to date and the kistamicin biosynthetic gene cluster
  JOURNAL   Medchemcomm (2017) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13047416)
  AUTHORS   Nazari,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) Chemistry, Princeton University, 20
            Washington Road, Princeton, NJ 08544, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUN-2015
            Assembly Method                   :: Celera Assembler v. Jun 2015
            Assembly Name                     :: SmrtPipe 1.87.139483
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 13:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 12,000
            CDSs (total)                      :: 11,919
            Genes (coding)                    :: 11,783
            CDSs (with protein)               :: 11,783
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 36 of 136
            Pseudo Genes (incomplete)         :: 98 of 136
            Pseudo Genes (internal stop)      :: 10 of 136
            Pseudo Genes (multiple problems)  :: 6 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:57:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10508101
            Orig. end                         :: 10539346
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017717.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..31245
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="30"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..31245
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31245
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17245]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..17245
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    402..416
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.93"
                     /tool="antismash"
     misc_feature    941..954
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.87"
                     /tool="antismash"
     misc_feature    1950..1964
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    complement(2028..2041)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.46"
                     /tool="antismash"
     gene            2113..3318
                     /locus_tag="BKM31_RS47900"
                     /old_locus_tag="BKM31_47540"
     CDS             2113..3318
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS47900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_47540"
                     /product="hypothetical protein"
                     /protein_id="WP_080044425.1"
                     /transl_table=11
                     /translation="MRRRVVGDGEHADRLLAAARACWGNGPGGAGCVVAEAYDEDLRVV
                     ARTLTVARVVCGLLKARLAVLTRPEWMPLARAFGAAQEPRPEAPPVALVTSRAEPAVPR
                     EIPVVHVHGTGTLQAYALFPDQGPCSLQDELPARIGAFFERHVWPHRALIRPGAERVAW
                     RARSGYQVRTDTERRQLRHQGCARLGLDADRPTIAVLGHAPDRDAELFGVTAALAAADE
                     RANWLFTDPVPADGHPRIRCVGGTLSTTMLWSMADAAVAFGDSDLPAFGIPVIQAGWSA
                     GGACGAAHVPGSPEEHRRLLEEAVARHAKGESLLGPEQRERARLWMWLRRCGADVPTQL
                     LAHWEQGSDYARTLAVNLRHVEPGADPLQGAVRRMWERREPLLTRFDFHDQGALACLGN
                     AR"
     gene            3432..4457
                     /locus_tag="BKM31_RS47905"
                     /old_locus_tag="BKM31_47545"
     CDS             3432..4457
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS47905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_47545"
                     /product="hypothetical protein"
                     /protein_id="WP_080044426.1"
                     /transl_table=11
                     /translation="MTSSGSATDLDQVILPAIPPVHLTNGRIAPLQVTDRLRRGSQIVG
                     RFETSGLAGFKVSAQGRPLRVLVSLSADERSVSGWYEGNTEPATLPRLIQIRSQGLLRQ
                     CVLLRGKRAHARVAFDLTPEEIPDDGLICVEALDITEGDGVCDEVRRAVSGRVAPDGVA
                     GVRLDKVVFEEPPPVDYDPDTLDGSRCEVYSLISAGGLANVNRQGVRVLRSGMFVVNPV
                     LKDRFGSSGRITLRLGTRAEAVSMIPATWRRLNSELRWLRHATRKMLHAAAPSVERIIS
                     IRDGDLGAPAQTVHGNITELHLDSPAGSPLLVILAPCPDSVPTLESGAAHQDQGSDPAD
                     G"
     gene            4469..5008
                     /locus_tag="BKM31_RS47910"
                     /old_locus_tag="BKM31_47550"
     CDS             4469..5008
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569423.1"
                     /locus_tag="BKM31_RS47910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47550"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_080044427.1"
                     /transl_table=11
                     /translation="MGDAVDRILDQWRRERPDLDLSAMGVFGRLAQVMRLMMPQVDQVF
                     TKRGLRQGEFDVLAALRRAGPPYTLIPSELSDVLMMSRAGMTNRLDRLEAAGLVERSLD
                     PADRRSFRVRLTEEGLRLIDDALTEHAANLARLAAPLTPEDVETLSELMRKLVNGPLGN
                     PGNDGARLTGKSSDHL"
     misc_feature    complement(5052..5066)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.93"
                     /tool="antismash"
     gene            5053..5484
                     /locus_tag="BKM31_RS47915"
                     /old_locus_tag="BKM31_47555"
     CDS             5053..5484
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.4"
                     /locus_tag="BKM31_RS47915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47555"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_186404516.1"
                     /transl_table=11
                     /translation="MRIETTRHLPCTVLRASGVLDHDGRVRFSARINDVWDWSPGPTLV
                     FDLADLDFFDSSVIGVLGLAMQRMAEEGSGRIFVVRPSDHLLSVLRLTDLLSRVEVRDS
                     VEETVAELMLEPEERGGPAAPARIPPQMTARLDVRRECG"
     misc_feature    5072..5085
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     gene            complement(5557..6963)
                     /locus_tag="BKM31_RS47920"
                     /old_locus_tag="BKM31_47560"
     CDS             complement(5557..6963)
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543312.1"
                     /locus_tag="BKM31_RS47920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47560"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_080044429.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8e-43, bitscore:
                     146.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADEFDVIVIGAGPAGENVVDRAVRGGLTAAIVEERLAGGECSYW
                     ACVPSKALLRPIDLAGEVARVPGLSLGPIDVAKVLARRDEAVSGYDDAGQVRWVEGVPA
                     EFVRGRGRLDGPKRVLVTGENGAERVLTARQAVVLATGSTAAIPPTPGLAEAAPWTSHE
                     VTAATAIPERLVVIGGGVVACEMAQAMHGLGARQTTVLVRGGGLLNRMEPFAGELLAES
                     FAEAGIDVRTHTDVVRVERPEPGGKVTVHLPEGPPLEADELLVATGRHPATRNLGLASV
                     GLPEDRPVEVDDSLRATGVEGGWLYAVGDVNGRVLLTHMGKYQARICGDVIAARARGDE
                     LPAMRDLAGGYGAPQVVFTDPQICAVGRTEEAARADGFRVRVVDYDMGAVTGAYLLGDG
                     YRGKARAIVDEDRKVLLGVTFAGPGAAELLHAATIAVTAEVPLDRLWHAVPSFPTVSEI
                     WLRLLETYGL"
     misc_feature    complement(6984..6998)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.04"
                     /tool="antismash"
     gene            7123..8226
                     /locus_tag="BKM31_RS47925"
                     /old_locus_tag="BKM31_47565"
     CDS             7123..8226
                     /EC_number="3.2.1.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024488.4"
                     /locus_tag="BKM31_RS47925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47565"
                     /product="sialidase family protein"
                     /protein_id="WP_080044430.1"
                     /transl_table=11
                     /translation="MADDYPTSVPFRQATDGYHTFRIPAAVVTRAGTVLAFAEGRRGSA
                     SDSGHIDLVLKRSSDGGRTWGGLQVVATEPQRGTAGNPAPVVLDDGRILLVFVRQGPSA
                     TEEKIRRGQVPAAAGRRVFAQVSEDDGATWSAPREITGSVKKPEWRWYATTPGHAVQLR
                     QGEHAGRVVVPANHSLPPSGQDNGTEGKYNGGHALLSDDGGQTWRIGYVDDNPDGYVNV
                     NETTATELPGGRLYLNTRTDSTAPGTRADACSADGGQTLELPFRPQAGLAGPVVEGSVL
                     WCDEPEVLLFSGPAAPDARALMTVRASHDHGVTWRVAHTVSGLPAAYSDLVRVDGETVG
                     LLFETGNFGPYESIAFRRIPVAELAAR"
     gene            8322..9257
                     /locus_tag="BKM31_RS47930"
                     /old_locus_tag="BKM31_47570"
     CDS             8322..9257
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540501.1"
                     /locus_tag="BKM31_RS47930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47570"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_080044431.1"
                     /transl_table=11
                     /translation="MDTEAVRSFVRAAELGQFQYAADELGVTQQAVSKRIAALERELEV
                     RLFTRTARGVELTPGGQAFLPHARGIVAGVEHAMGAVRPDARLLRIDVLGFRSAQAVVL
                     HDYWRSNPGIQLDVVALKAGDPGTAVAAVRAGEVDASFRAVTDPAALPRDVEMARVLDV
                     PLELLVGPGHPLAAARTVTPEQLRPHRIRIAGLAPRSEWADFYDQLATAFGLRIDGEGP
                     NFGIEPLLDTLAESGDVATLVGARDRLAWPAGHDLRRIPIVDPVLAYPHALLMPRANPH
                     PRLRPIIDYFRSLAGAPRTAWVPSWATSRR"
     gene            complement(9254..10177)
                     /locus_tag="BKM31_RS47935"
                     /old_locus_tag="BKM31_47575"
     CDS             complement(9254..10177)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS47935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_47575"
                     /product="hypothetical protein"
                     /protein_id="WP_222107664.1"
                     /transl_table=11
                     /translation="MRVKPRRSLFLRLLLVPALAVAAWAPAAAAVAQDNVIVLPGATSA
                     EGIAAGPGGTFYAGDLFGGDIFRGDARRGTAERFIDAPDGRMAVGMVADHRHGLLFVAG
                     GFTGQAYVYDLRSGVEVATYQLAAPDAGLINDAALGRDGVWFTNSGRAELYFVPIGHKG
                     RLGPARTLTVTGPAADTSGEVNLNGIQVAGRTPIVAHTGLGRLYTVDPATGASTPIAGV
                     DVPSPDGLVLSGDRLWVVNSTSQVSRFRLSHDLSGGVLEKTITSPLFDFPTTAALIDRH
                     RLAVVNGHLGTIPPTSPTYEVIVVEP"
     misc_feature    complement(10151..10153)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10187..12043)
                     /locus_tag="BKM31_RS47940"
                     /old_locus_tag="BKM31_47580"
     CDS             complement(10187..12043)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543311.1"
                     /locus_tag="BKM31_RS47940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47580"
                     /product="CheR family methyltransferase"
                     /protein_id="WP_080044433.1"
                     /transl_table=11
                     /translation="MTTEEEREFDDLLLLLKETRGFDFTGYKRNTLIRRIARRLEALKL
                     HDYGEYRDLLELEPEEFTRLFDSLLINVTSFFRDAAAWQRLRELVIPALLDQKPAGQPI
                     RIWSAGCATGEEAYTIAMVLAEELGMDGFRDRVKIYGTDLDEKALHVARTGVYNDRALA
                     DVPIDLREAYFERVENGYTFRRDLRRQLIFGRNDLTHDAPISRVDLLLARNTLMYFNTE
                     MQLNIIRRFHFALSDPGFLFLGKAEMLLNHSDKFEPVDLRMRLFRKIRPANHGNRAPWS
                     VTGAATDLASRLPTLASVALASGPVAQLVVDVSGNLALANSKAEALFNLNPRDVGRPFQ
                     DLEVSYRPVELRSVIEQARHDLRPVELQDVVWHRVGSPEPSVFDVSVVPLLASGNLVGM
                     GIHFYDVTRYRKLRDELEQANRQLEQAYEELQSLNEELETTNEELQSTNEELETTNEEL
                     QSTNEELETMNEELQSTNDELQHINDALTARTIELDEVNRFVSSVVRSLGDAVVVLDDD
                     LRVVVWSPGAEELWGVRSDEAVGEPLAGLDIGLPLDLLLPRLRAALANGTNPLVEVEGL
                     VLDAVNRRGRPAPLTVQLSHLRTEDDTVHGLIMVMNVVNSDG"
     gene            complement(12072..13082)
                     /locus_tag="BKM31_RS47945"
                     /old_locus_tag="BKM31_47585"
     CDS             complement(12072..13082)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013502.4"
                     /locus_tag="BKM31_RS47945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47585"
                     /product="chemotaxis protein CheB"
                     /protein_id="WP_080044434.1"
                     /transl_table=11
                     /translation="MEAPGRDVVVVAASAGGVESLRVLLSELPADLPAAVLVVLHVPPQ
                     GSSRLAGILDRAGPLKAAPAEDQEIIRPGRVYVARPDFHLLMSDGMIRLTRGPQHNGHR
                     PAADPLFVSAALDAGARVAAVVLSGTLDDGARGCEAIYKHGGAVAVQDLAECAFPGMPR
                     AAMTAVPAARALPVRELAGWVLEQSRTPVSTEVQVYDNEMEREIEQFLREAPSLGEPEG
                     ELIAFSCPECNGPIYEQKSATSSRYVCRVGHAWSRDSMINAQSDAVERALWVAIQRLEE
                     RLRVLERMRRSAEERGQELSLRYFHEEEERTSEALNTIRMLQSRIGRNGDTLLAD"
     gene            complement(13121..13888)
                     /locus_tag="BKM31_RS47950"
                     /old_locus_tag="BKM31_47590"
     CDS             complement(13121..13888)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.4"
                     /locus_tag="BKM31_RS47950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47590"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_080044435.1"
                     /transl_table=11
                     /translation="MMQLSVRLVPVDDTTLVIALTGELDSTTKPVLAAFLDPLPQTTVK
                     HVLVAAGDLWFCDLNGLDLLARTHRALQEKGGHLALAEVQPPLRRLIALMTEQSAATIP
                     VFATMAEALAAAGVEAYQPAEPALRRRHLPRLRTVPRAPSPVRAQARSRREPAPAQAAQ
                     AAQAARPSAAEIELDVSSLPSVIFEARSLRDQALHQQQALNNRLTAAAQARARLLTTRR
                     RCDDSLMAMRSSLSEARSILTLAEASQERPHLS"
     misc_feature    13904..13922
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.29"
                     /tool="antismash"
     gene            complement(14001..15545)
                     /locus_tag="BKM31_RS47955"
                     /old_locus_tag="BKM31_47595"
     CDS             complement(14001..15545)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543309.1"
                     /locus_tag="BKM31_RS47955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47595"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_080044436.1"
                     /sec_met_domain="IucA_IucC (E-value: 5.1e-28, bitscore:
                     97.6, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRLEGEFAAELALVRPDLSDRYTAALPGARAAVLGRLWRGLLYE
                     PLPRLTATGPSRVLLADGRELTGPERRPYDLREEPELRLAGRPYRHPAELLAALGLPGS
                     ARLVDDLDHSVASMALSRAGASPRPGDTVEDHEQSVVDGHPYHPGCRNRPGVSVAEQLA
                     YMPEHRPTVALDLLALPLRECLVTGPWPASLVDGDRLLLPVHPWQTRHVLPALGLRPHA
                     TGVVRARPLMSVRTLAPLDGGPHLKTAFTTRMTSGIRDISPGSVRDCVPLSDLLTTLAA
                     KCGGTLRIARYLAGAAGQVAGRHSADLSCMLREPTAEPGTVLPVAAVTRSMVSDPAAWL
                     AAFARLALTDTLGLLALGVALEAHGQNLLVALGADGLPYRLVYRDLADVRISPARLARH
                     GIEVPPVSPRLLSDDPAVLHAKLFGSLAGTTFGSLIALFGQGDRDAEDRLWEVVAAAAR
                     RAFAALPDTPDVRAARGALFGARLMVKAHLVARLDGAPPGDSWTGLPNYLGAHSHA"
     misc_feature    complement(15534..15536)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15553..15566
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.82"
                     /tool="antismash"
     gene            15626..17245
                     /locus_tag="BKM31_RS47960"
                     /old_locus_tag="BKM31_47600"
     CDS             15626..17245
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543308.1"
                     /locus_tag="BKM31_RS47960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47600"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_186404515.1"
                     /sec_met_domain="IucA_IucC (E-value: 8.1e-39, bitscore:
                     133.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFTDGLLPAAGPGLEAESLAVTALLNCLLREVATPADPSAPAGP
                     VASAEPFASAGPFAPAEPRFFVLPATGHVLRVGGARFPAEPALRTPDGWRPIPLPELVE
                     LTAAELRAATGAANDALPGEILDSRDVTAVLLAARRATVPPADAYLRSEQALVAGHRYH
                     PAPKARGGGGPREWLRYSPEARASFALPLLAVPADDLVVDGDASALDRLGPAPGAGLAL
                     LPAHPWQLELLGETGLRQAGVSAATAVATASIRTVYLPEADLFCKFSLDVRITNDVRRL
                     WLHDLRRLSLVAALVDVAFDDLPCHLPRPAVLRDRGWRSARLGGDGGEGLAVIVRDGLG
                     EHLLPGLTALLAAGISEGFPGNPIDGLDEDGALVWWERYLEHVVPPVLHAYLRHGVVLE
                     CHLQNVLVAVDAHGLPGQALFRDHEGVKLVAERHPGLTAPVLGGVRAWERLVYCLLTNN
                     LCEIAGAVAERHPRLVGELWTRARAVFAAAAKEYGDPPELRDLLAATHIPAKANLLLRW
                     LDADGAAMRWVPIPNPLRLFAP"
     gene            complement(17354..17896)
                     /locus_tag="BKM31_RS47965"
                     /old_locus_tag="BKM31_47605"
     CDS             complement(17354..17896)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017614616.1"
                     /locus_tag="BKM31_RS47965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47605"
                     /product="DUF6789 family protein"
                     /protein_id="WP_186404514.1"
                     /transl_table=11
                     /translation="MTQTLQKPAHLREDVQPERERRPIVRAAARGVIGSMAMSGLRQLT
                     TALGMVPSTPPESVLKRTAPKAFHSVPDERRPAVVEAVHWTYGAVGGAFFGLLPKAVRR
                     RRWAGPVYGVLAWAAFETAIAPALGLTRRHGRAERVALLADHVLYGIVVGAAPRPSKKR
                     HHEDAEQAPPSWLQERP"
     gene            complement(17926..19350)
                     /gene="rfaE2"
                     /locus_tag="BKM31_RS47970"
                     /old_locus_tag="BKM31_47610"
     CDS             complement(17926..19350)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="rfaE2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012515.4"
                     /locus_tag="BKM31_RS47970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47610"
                     /product="D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase"
                     /protein_id="WP_080044438.1"
                     /sec_met_domain="CTP_transf_like (E-value: 3e-15, bitscore:
                     56.1, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTDEIINAVVVGDVMLDSWLHGSAKRLAQEAPVPVMSLEATEDA
                     PGGAANTAANLVALGARVRLVGVVGDDECGEKLDNALRLLGVGTDLLTVPGRRTAHKRR
                     LVTSGQLTARYDEEDLSVIPEDAERDLLARVEEAVAGADVVVACDYGGGVCTPAVRRAL
                     AGLPLLVVDAHAVAPWRECAPAAVLPNYAEVVRLLGDDGGAVDRPAYLMGRSERLLELT
                     GAGIVVTTLDGEGTLLHRRGHPPYRTYAQPAPQHMATGAGDTYTAAFALWLASGASPEE
                     AAEAGQAAAGVVVRRQGTAVCTRYDLVRALRRQEGTVQTAERLAQLLDEHRRRGERVVF
                     TNGCFDVLHRGHVTYLEQAGQLGDVLVVAVNSDASVARLKGPGRPVNSCEDRMSVLAAL
                     NDVDYVTEFDEDTPERLIRMMRPELYVKGGDYTAEMLPEAPLVRALGGEVRVLGYLPDR
                     STTAIIGRMRSLPEEV"
     gene            19434..20249
                     /locus_tag="BKM31_RS47975"
                     /old_locus_tag="BKM31_47615"
     CDS             19434..20249
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /locus_tag="BKM31_RS47975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47615"
                     /product="glycosyltransferase"
                     /protein_id="WP_080044439.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2e-10, bitscore:
                     40.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRPSDLDVLVPTRDRPAALAVTLAGLAAQSARGFRVVVSDQSEM
                     PVTGDPLVASAVRILEHLGSEVALLRHVPARGLAEQRQYLLEQAGRPLCLYLDDDVWLE
                     PDAVGVLLAAMAQLRCGFVGYGLHGLSYRDDRRPDELEPYEEWAREVWPERVRRGSPAW
                     GRHTLHNAANPLHLAERVGARLAWQAYKVAWIGGCVLYDRERLEECGGFAFWRSVPPAH
                     AGEDVVAQLRVMERYGGAGLLPSRAYHLELPTTVVDRGAECYDYVLDRA"
     gene            20246..21322
                     /locus_tag="BKM31_RS47980"
                     /old_locus_tag="BKM31_47620"
     CDS             20246..21322
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_transf_9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543304.1"
                     /locus_tag="BKM31_RS47980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47620"
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="WP_080044440.1"
                     /sec_met_domain="Glyco_transf_9 (E-value: 8e-27, bitscore:
                     93.7, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAPGPDTRALIGDVRRIAVLRANAIGDYLMAVPALEALKRAYPG
                     ARLTLLGTAWHAAFLTGRPGPVDDVVALPPISGVSTREPGHRAPEELCERLRQREFDLA
                     VQIHGGGRFSNPFVRRLGARVTAGLRAPGAERLDRWVPYTDYHHETLRFLQVAALVGAV
                     DGGLEPRVAVTAADRADLARALGQPPAGLVAVHPGATDPRRRWPVERFAEVADQTGRPV
                     VVTGTRDEQDLVMGVVEAMRRPAIPVVGALGLGGLAALYERCDLVIANDTGPRHLAAAV
                     GTPTVAIYWCGNLIQAGPLSRTAHRPLISWTTACPRCGAAGVDPAAERCPHDESWVRDV
                     TVDMVAEQVDDLLTKGDR"
     gene            21319..21654
                     /locus_tag="BKM31_RS47985"
                     /old_locus_tag="BKM31_47625"
     CDS             21319..21654
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS47985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_47625"
                     /product="hypothetical protein"
                     /protein_id="WP_155128894.1"
                     /transl_table=11
                     /translation="MSGHAVLDELRQAIDEVFHGRERVAMRDVYAQASRHVNLSADLLT
                     HLNELPEGPYDRRELTEAINEVITRRGEQDTLGLLEVPQQAGAAPLEYVNPTPTVPDEN
                     EGPDLMR"
     gene            21732..22253
                     /locus_tag="BKM31_RS47990"
                     /old_locus_tag="BKM31_47630"
     CDS             21732..22253
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012886898.1"
                     /locus_tag="BKM31_RS47990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47630"
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_080047418.1"
                     /transl_table=11
                     /translation="MDAADEQRFREFVDARSPALMRLGYLLTGGDQHAAEDLVQTALAR
                     LAAKWRRVTAPEAYAKQIMYRQQVSWWRASTRRGEVLQAGPPEREARDAHHQSELRLVL
                     RSALARLTARQRAVVVLRYYEDLPEQEVAQVLGCSVGTVRSTAHRSLARLRETAPELAL
                     ELARDLEVTT"
     misc_feature    21975..21977
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            22250..23440
                     /locus_tag="BKM31_RS47995"
                     /old_locus_tag="BKM31_47635"
     CDS             22250..23440
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS47995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_47635"
                     /product="hypothetical protein"
                     /protein_id="WP_080044442.1"
                     /transl_table=11
                     /translation="MTRLLRDTLEDWAGEARVPPGLADRALRRRAWKPYGAAVLVAAMI
                     AAVAVFVTVQRDPVPPVARPLSGITLPPRPSPAPTDIRTDTEHSPPAKLVAAGRMAVSA
                     YYVTRQEPVEGDRTRVRRTWSVYDPGTDGYRETPYAWVDVAPGLQVAAVIQGDLIGNRV
                     GVLNLDTGQMLATYELEHPVGSVVWSPDGTRILATAYSSYPDVFQEDSAEMGSPRTGYY
                     VIDTGTGESVYHELPPLPDGIYSDAEYTNGNGRQDLGWSLDGELIWGPTSSSPDRRFYT
                     LDGSPTDAPKGERYRRGSGLSATSPDGQLVLGDDGMPTKITEAATGKVVGRQRVLQLHA
                     WADNDNVLALGCAGKCENEFNNGLVLVSVDGSKTIQLAANRDSDADGSWRWVLTPR"
     gene            23481..24023
                     /locus_tag="BKM31_RS48000"
                     /old_locus_tag="BKM31_47640"
     CDS             23481..24023
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017601873.1"
                     /locus_tag="BKM31_RS48000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47640"
                     /product="GNAT family protein"
                     /protein_id="WP_080044443.1"
                     /transl_table=11
                     /translation="MLKGKKIGLRARHEDDIPILLTELYDDPVNSSRAEGGPWRPITPG
                     TNDSRLVPDDKDQSKVPFSVVELDGGTLVGSANLWGIDTHNRSAHIGLGLLPSCRGKGY
                     GSDVVATLCHYGFVLRGLRRLQIETLSDNYAMLRAAERNGFVREGVLRSSAWVLGRFMD
                     EVLLGLLAEEWKPDTPS"
     gene            complement(24035..24688)
                     /locus_tag="BKM31_RS48005"
                     /old_locus_tag="BKM31_47645"
     CDS             complement(24035..24688)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890863.1"
                     /locus_tag="BKM31_RS48005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47645"
                     /product="response regulator transcription factor"
                     /protein_id="WP_080044444.1"
                     /transl_table=11
                     /translation="MAAVIRVLLVDDDALVRAGLSMMLDGAAGITVVAEAADGQEAITA
                     TDAHAPDVVLMDLRMPRLDGITATRRLRARARPPEVIVLTTFDTDENVLHALRAGAAGF
                     LLKDTPPPRIVEAITRVSAGDPILSPHITRRLMERTIAQAGAYERARAALAALTPREHE
                     VALAIAQGRTNADIAADLVMGVTTVKAHVSSILTKLDLDNRTQIALLAHDAGLI"
     gene            complement(24676..25806)
                     /locus_tag="BKM31_RS48010"
                     /old_locus_tag="BKM31_47650"
     CDS             complement(24676..25806)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019607310.1"
                     /locus_tag="BKM31_RS48010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47650"
                     /product="histidine kinase"
                     /protein_id="WP_080044445.1"
                     /transl_table=11
                     /translation="MSQIRPSHPLAVAAVGLTIGALSTVSLWDREVGPTWWLDVAVAAV
                     SLVAALAQLRWPVHGALAATVLATLSPAATPAATTGALQVAQRRRFPVAAAVTAAGMAA
                     HLVQGLWRPNSGISFGWWLLLICAAYGALLGWGALARSRRALLISLRERAARAEAEQGR
                     RVAEARMAERHRLAREMHDVLAHRLSLVATHAGALEYRPDASPDRIAKAAGVVRTGVHQ
                     ALEELRQVIVLLREQDDEGDDLEPHPDLADLPGLVAEAREAGQPVRLREGITGTTSLPP
                     AVSRTAYRVVQEGLTNARKHAPGEPVEVLLEGAPGTPLLIDVRNPLPPPGTAPIVPGSG
                     LGLVGLTERVRLAGGRLDHQGTGAEFVLRARLPWPP"
     misc_feature    complement(24691..24693)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(25844..26002)
                     /locus_tag="BKM31_RS60775"
     CDS             complement(25844..26002)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS60775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_155128896.1"
                     /transl_table=11
                     /translation="MSLGLLREEEGVGLLFVETFLMRISLARHPAPPHRAPGRAVPSPS
                     GVRLLLS"
     gene            26001..26543
                     /locus_tag="BKM31_RS48015"
                     /old_locus_tag="BKM31_47655"
     CDS             26001..26543
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039977.3"
                     /locus_tag="BKM31_RS48015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47655"
                     /product="DUF6069 family protein"
                     /protein_id="WP_222107663.1"
                     /transl_table=11
                     /translation="MNTPANPTPAGTTPAGTTPAGTTSAGTTSAGATPTGTTSAGTTSA
                     GATPTGTRPARTRVRRLLVVIGASVAALAGWDLAVPVGGADLSARMGAGTDPQPVGPVA
                     VVVASLLVGLAGWALLAVLERFTPRAARIWTIVALIVLALSLLGPLGNAVGLAATLVLT
                     AMHLVVGAVLVTGLPRR"
     gene            26575..27465
                     /locus_tag="BKM31_RS48020"
                     /old_locus_tag="BKM31_47660"
     CDS             26575..27465
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540091.1"
                     /locus_tag="BKM31_RS48020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47660"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_080044446.1"
                     /transl_table=11
                     /translation="MTVLARAIDVTRRYGGVRALDGVSLDIRAGELVGLLGPNGAGKST
                     LINLLVGLRRPTSGTVELFGGSPLDPVMRRGIGVTPQETGLPESLRVGEIVDFVSAHYP
                     ERLGTGELLARFGLGELVRRQVGGLSGGQRRRLAVALAFAGRPKLVFLDEPTTGLDVEA
                     RRALWDGIKAFHEDGGTVLLTSHYLEEVEALAERVLVVGQGRVLADDTMRAVRGLVGTR
                     RVSLVADRLPDLPGVLSAERVDGRIDLVVTDPDRLVVELVRAGVPFSGLEIRPATLEEA
                     FLALTTNPPKETAHV"
     gene            27458..28198
                     /locus_tag="BKM31_RS48025"
                     /old_locus_tag="BKM31_47665"
     CDS             27458..28198
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540092.1"
                     /locus_tag="BKM31_RS48025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47665"
                     /product="ABC transporter permease"
                     /protein_id="WP_080044447.1"
                     /transl_table=11
                     /translation="MSNLVLAHTRYLVIEQIRVPIGILASAFFPALSMVAFVVPFAGQD
                     PVGATTATGSLMLFGAVSAALTGLGIAVSQDREQPWNPYLRTLPAGPLPRFAGRILATL
                     AAVLISVVPVLVVGALLTEATITPVRLLAGLGALVAGVLPFMLMGLFVGFVLASKAAMA
                     VSQLLFFPMAILGGLLLPPAVMPEFVQALSPYVPTRGAAELVWWAIAGIPANGVSMAML
                     AVWTVAMAAAAGWAYRRDEGRRFS"
     gene            28245..28823
                     /locus_tag="BKM31_RS48030"
                     /old_locus_tag="BKM31_47670"
     CDS             28245..28823
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543300.1"
                     /locus_tag="BKM31_RS48030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47670"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_080047420.1"
                     /transl_table=11
                     /translation="MARTKEFDPEVALQRALELFWERGYEATSMADLVDRLGVARASIY
                     ATFGGKRELYLKALERYLEQRNVVEPLSQPGPALPAIRAFLDSYVAEILADELRRGCMV
                     VNTAVEFASRDATVLAKVAASWAELETALAGTLVRARAQGEIPAGKDPYALARFLLVLL
                     QGLRVLGRADPDPRRLRDAVDQAMTAVQI"
     misc_feature    28830..28846
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            28845..29606
                     /locus_tag="BKM31_RS48035"
                     /old_locus_tag="BKM31_47675"
     CDS             28845..29606
                     /NRPS_PKS="Domain: PKS_KR (8-174). E-value: 7.3e-09. Score:
                     27.7. Matches aSDomain:
                     nrpspksdomains_BKM31_RS48035_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543299.1"
                     /locus_tag="BKM31_RS48035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47675"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_080044448.1"
                     /sec_met_domain="adh_short (E-value: 3.8e-29, bitscore:
                     101.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQRFAGKVALVTGASGVVGRAAALAYAREGAAVLVAGRDADRLA
                     EVVKAIEADGGRAGAFTADLTRSSDVAAMVEAAVSRFGGLDVALNTAGVFGMLAPLADY
                     DEDVWDDVLAINLKGVFLSMKHEIAHMRAHGGGVIVNVSSNLGAHWRLAGASAYAASKA
                     AVSHLTRAAARDHIADGVRINALSPGPIDSPMSARPGETREQRDERMRAALPIGRVAAP
                     EEIAAAALWLSSPESSFVVGADHVIDGGATA"
     aSDomain        28869..29366
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS48035_PKS_KR.1"
                     /evalue="7.30E-09"
                     /label="BKM31_RS48035_PKS_KR.1"
                     /locus_tag="BKM31_RS48035"
                     /protein_end="174"
                     /protein_start="8"
                     /score="27.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGASGVVGRAAALAYAREGAAVLVAGRDADRLAEVVKAIEA
                     DGGRAGAFTADLTRSSDVAAMVEAAVSRFGGLDVALNTAGVFGMLAPLADYDEDVWDDV
                     LAINLKGVFLSMKHEIAHMRAHGGGVIVNVSSNLGAHWRLAGASAYAASKAAVSHLTRA
                     AAR"
     CDS_motif       28875..28952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS48035_0001"
                     /evalue="3.60E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="BKM31_RS48035"
                     /protein_end="36"
                     /protein_start="10"
                     /score="6.8"
                     /tool="antismash"
                     /translation="LVTGASGVVGRAAALAYAREGAAVLV"
     gene            complement(29611..31068)
                     /gene="rox"
                     /locus_tag="BKM31_RS48040"
                     /old_locus_tag="BKM31_47680"
     CDS             complement(29611..31068)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene="rox"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545703.1"
                     /locus_tag="BKM31_RS48040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_47680"
                     /product="rifampin monooxygenase"
                     /protein_id="WP_080044449.1"
                     /transl_table=11
                     /translation="MVSSKADRAPLSFDVIIAGCGPTGAMLAAELRLHDVRVLVLEKDT
                     EPGSFVRIVGLHVRSLELLAMRGLLERVAAHGRKRPAAGLFAGIHKPAPAGLDSAYGYL
                     LGIPQPVVNRLLEEHAVALGAQVRHGCAVAGLEQDDEGVTVELADGERLRSRYLVGCDG
                     GRSTVRKLLGVGFPGEPARADTLMGEMEVGVPPEEVAAALRRLGDTPQRFWLRPFGEKV
                     YSVVVPAAEVGDRAVPPTLDDFRRQLRAVAGTDFGVHSPRWMSRFGDATRLAEHYRVGR
                     VLLAGDAAHIHPPTGGQGLNLGVQDAFNLGWKLAGQIRGWAPGTLLDTYHAERHPVAAD
                     VLDNTRAQMELYSAEPGARAVRRLLTELMDFDVVNRHLTEKITAISVRYDLGEGHDLLG
                     RRLPDVEVKQGRLYDLLHQGRGLLLDRTGRLSAGGWADRVDLLADPTADLDVPGVLLRP
                     DGYVAWVGDGQRELDGRLRQWFGEPTS"
ORIGIN
        1 ggcgaaccag gccgtggcct gcgcgtcggt ggtgccggtc ttgcccgccg cgggccggcc
       61 gatgccgccc acgccccgca tcgtgccctt ggtgaacacg ccggacagga tgttcgccgc
      121 cgcgtcggcc acctccgggt cgagcgcctg cttgcacttc ggcttgaagt tcgtcacctt
      181 gccgttgcgg tcggtgatct tggtgatcgc catgggcgcg cagtacttgc cgcgcgcgcc
      241 gatggccgcg tacgcgttgg ccaccgtcac cgggtccatc tcgttggtgc ccagcgtgaa
      301 cgtctcgaac tcggtcagcg gcagcccgtc ggagcgcttg atgcccagcg acttggccgt
      361 cttgatcgtg tcacacaggc cgacgtgctc ctccagcttc atgaagaacg tgttcaccga
      421 cccccacgtg ccggtctgca gcgacttgaa gccgccgccg ccctcgtcgt tggtgacggt
      481 gtggctcggg tcgccgatgg gctcgccctt gcagttcttg aaggtggagt agtacggggc
      541 gcggtagccg ctgccgacgc tgaacccgtc gttgatcttc atgccctcct tgagggccgt
      601 gagcagcgtg aacgtcttga acgtcgagcc cgcctggaag ccgacgccgc cgccgtgcac
      661 ggcgtccgcc acgacgttgt acgacatctc cttcttgcgc ttgctgttgc cgtacttgcg
      721 gctggcggcc atggccttga tctggcccgt gcccggctgc accagcgcct cggaggcgac
      781 cgggttgtcg gaggcgaaca cgtgcttctt gatcgccttc tcggcggcct tctgcatctt
      841 cgggtcgagc gtggtctgga tcgtcagccc gccccggttc aggtactggc tgcgcgcctt
      901 ggccgtcttg ccgaagtcgg agttgctgag gatctcgttg cggacgtaca tgcagaagta
      961 cgggtacggg ctggcctcgc agccgcccgg caggggagtg cccttgtagc cgagcggctt
     1021 cttcttggcc tcggccgcct cctccggcgt gatcttcttc agctcggcca tccggtcgag
     1081 caccacgttg cggcgggaga gcagcttcgc ccgctgcttc ttgcccaggt tggggtcggt
     1141 ggcgttcggg tcctggacgg cgccggccag cgtcgcggcc tgcacgaggt tcagctccga
     1201 cgccttcacg ccgaagaagc gcttggccgc ggcctcgatg ccgttggcgt gggcgccgaa
     1261 gtaggcgatg ttgaggtact tctccaggat ctggtccttg gtgtacttct cctcgaccgc
     1321 catggcgtac cgcagctccc tgagcttgcg cgcgtagctg gcctccagtg ccgccgcctg
     1381 ctcctccttg gtggtcgccg agttgagcag cacctgcttg acgtactgct gcgtgatgga
     1441 cgagccgcct tgggcgatgc cgccggaggt gaagttcttc gccagggccc ggatggtgcc
     1501 ctcgatgtcg atcgcgccgt gctcgtagaa gcggaagtcc tcgatcgaga tgatcgccgt
     1561 cttcatgatg ggggcgacct ggtcaagggt gatcgtctcg cggtactcct cgtagaactg
     1621 cgcgatcggg ttgcccttgg cgtccaggac ggtggtcttc tccgcgagcg ggggctcctt
     1681 gaggtcctcg ggcttgatgc cgagatcctc cgatgccgag acgaacatcg ctcctgtacc
     1741 cccgaccgcg ggcagcgcga tggccgcggc caccacaccg gccgcagccg ccgccgccgt
     1801 caggcgcgcg acactcgaca aacgggaacc catgctggta aaacctcccc atcctggcaa
     1861 tatggtgcat cctaaacccg ggcatgacct gctccgtgta aagacttgga cgccccgttg
     1921 ccccggattg ttcggggctt ttcgccggaa tcacggccat cgacgggttc gtgcagcgtg
     1981 gggcacgtga gacgtgtggg actgttcgag attccgccag gctgaggcaa agaagcgtgt
     2041 cgcccgcgcg gccccgggaa acccgtctgg caacgtctac cagggcattt ttctcactgg
     2101 tggaggggct tcatgcgtcg tcgcgtcgtc ggcgacggcg agcacgccga tcggctgctc
     2161 gccgccgccc gggcctgctg gggaaacggt ccgggcggtg ccggctgcgt cgtggcggag
     2221 gcgtatgacg aggatctgcg ggtcgtggcg cgcacgctca ccgtcgccag ggtcgtctgc
     2281 gggctgctga aggcccggct ggccgtcctg accaggccgg agtggatgcc gctggcccgc
     2341 gcgttcggcg ccgcccagga gccgcggccc gaggcgccgc ccgtcgcgct cgtcaccagc
     2401 agggccgagc cggccgtgcc gcgcgagatc cccgtcgtgc acgtgcatgg caccgggacg
     2461 ctgcaggcgt acgcgctctt ccccgaccag gggccgtgct cgctccagga cgagctgccc
     2521 gccaggatcg gcgccttctt cgagcggcac gtctggccgc acagggcgct gatcaggccc
     2581 ggcgccgagc gggtcgcctg gcgggcgagg agcggctacc aggtccgtac ggacaccgag
     2641 cgccgccagc tccgccacca gggctgcgcc cggctcggcc tcgacgccga ccggcccacg
     2701 atcgcggtgc tcggccacgc gccggaccgg gacgccgaac tgttcggcgt gacggccgcg
     2761 ctcgccgccg ccgacgagcg cgccaactgg ctcttcaccg accccgtgcc cgccgatggg
     2821 catccccgca tccggtgcgt gggcggcacg ctgtccacca ccatgttgtg gagcatggcg
     2881 gacgccgccg tcgcgttcgg cgacagcgac ctgcccgcct tcggcatccc cgtcatccag
     2941 gccggctggt cggcgggcgg ggcctgcggg gccgcgcacg tgccgggctc gccggaggag
     3001 caccggcggc tgctcgaaga ggccgtcgcc cggcacgcca agggcgagtc cctgctcggg
     3061 cccgagcagc gcgagcgggc ccggctgtgg atgtggctgc gccgctgcgg cgccgacgtg
     3121 cccacccagc tcctggcgca ctgggagcag ggcagcgact acgcccgcac gctcgccgtg
     3181 aacctgcggc acgtggagcc gggcgccgac cccctccagg gggcggtgcg gcggatgtgg
     3241 gagcggcgcg agcccctgct cacccgcttc gacttccacg accagggcgc gctcgcctgc
     3301 ctggggaacg cccgatgagc cttcccgggg ggcgtcccct tcgagaacac ccgtcgcgtc
     3361 cttccgcggg acgcccgccg agtcccatga gcggccgccc cggtgcggcc ccttccctcc
     3421 aggagcatcc gatgaccagc tcaggatccg ccaccgacct ggaccaggtg atccttcccg
     3481 ccatcccgcc cgtgcacctg accaacggcc ggatcgcgcc gctccaggtc accgaccggc
     3541 tgcggcgcgg cagccagatc gtgggcaggt tcgagacctc cgggctggcc gggttcaagg
     3601 tctcggcgca gggccggccg ctgcgggtgc tggtgtcgct gtcggccgac gagcggtcgg
     3661 tgagcggctg gtacgagggc aacaccgagc cggccacgct gccccggctg atccagatcc
     3721 gctcccaggg gctgctgcgc cagtgcgtgc tgctgcgcgg caagagggcg cacgcccgcg
     3781 tggcgttcga cctgacgccg gaggagatcc ccgacgacgg cctgatctgc gtcgaggcgc
     3841 tcgacatcac cgagggcgac ggcgtctgcg acgaggtgcg ccgggccgtg tccgggcgcg
     3901 tcgcccccga cggggtggcc ggggtgcggc tggacaaggt cgtgttcgag gagccgccgc
     3961 cggtggacta cgaccccgac acgctcgacg gctcgcgctg cgaggtgtac tcgctgatca
     4021 gcgccggcgg gctggccaac gtcaaccggc agggcgtgcg ggtgctgcgc tccggcatgt
     4081 tcgtggtcaa cccggtgctg aaggaccggt tcgggtcgag cgggcgcatc acgctccggc
     4141 tcggcacccg ggccgaggcg gtcagcatga tccccgcgac gtggcggcgg ctcaacagcg
     4201 agctgcgctg gctgcggcac gccaccagga agatgctgca cgcggcggcg ccgtccgtgg
     4261 agcggatcat cagcatcagg gacggtgacc tgggcgcgcc cgcgcagacc gtgcacggca
     4321 acatcaccga gctgcacctg gacagcccgg ccggctcgcc cctgctggtg atcctcgccc
     4381 cctgccccga ctccgtgccc accctggagt cgggtgccgc gcaccaggat caggggagcg
     4441 accccgccga cggctaagat gcgaggtcat gggcgacgcc gttgacagga tcctcgatca
     4501 gtggcgccgc gagcggcccg acctcgacct gtcggccatg ggcgtcttcg gccggctggc
     4561 ccaggtcatg cggctgatga tgccgcaggt cgaccaggtc ttcaccaagc gcgggctgcg
     4621 gcagggcgag ttcgacgtcc tggccgcgct gcgccgggcc gggccgccgt acacgctgat
     4681 cccctccgag ctgtccgacg tgctgatgat gtcgcgcgcc ggcatgacca accggctcga
     4741 ccggctggag gccgccgggc tggtcgagcg cagcctcgac ccggccgacc ggcgcagctt
     4801 ccgcgtccgg ctgaccgagg aggggctgcg gctgatcgac gacgcgctca ccgagcacgc
     4861 cgccaacctc gcccgcctgg ccgccccgct cacccccgag gacgtcgaga cgctctccga
     4921 gctcatgcgc aagctggtca acggtcctct tggtaatccc gggaacgacg gtgcccgatt
     4981 gaccgggaaa agtagcgatc acctgtgata acgccgctga gcgggcaggg gattcaggtg
     5041 ggcacgagcg gtttgcgaat cgagacgacc cggcatctcc cttgcacggt cctgcgcgcc
     5101 agcggcgtgc tcgaccacga cgggcgcgtc cgcttcagtg cccgcatcaa cgacgtgtgg
     5161 gactggtcgc ccgggccgac cctcgtgttc gacctggccg acctcgactt cttcgactcg
     5221 tcggtcatcg gggtgctggg cctggccatg cagcggatgg ccgaggaggg cagcggccgg
     5281 atcttcgtgg tccggccgtc cgaccacctg ctgtcggtgc tgcgcctgac ggacctgctc
     5341 tcgcgcgtgg aggtgcgcga cagcgtcgag gagacggtgg cggagctgat gctggagccg
     5401 gaggagcgcg gcgggcccgc cgcgcccgcc cggatcccgc cgcaaatgac cgcgcgcctg
     5461 gacgtgcggc gggaatgcgg ctgaccggcc ggcgcccctc ctccaggctg taggtctcgg
     5521 cggacctcct ccaggccgta ggtctcggcg gacctcctac aggccgtagg tctccaggag
     5581 gcgcagccag atctcgctca ccgtcgggaa cgacggcacc gcgtgccaga gccggtcgag
     5641 cggcacctcg gccgtcaccg cgatcgtcgc cgcgtgcagc agctcggccg cgccggggcc
     5701 ggcgaaggtg acgccgagca gcaccttcct gtcctcgtcg acgatggccc tggccttgcc
     5761 gcggtagccg tcgcccagca ggtaggcccc ggtgaccgcc cccatgtcgt agtcgaccac
     5821 gcgcacgcgg aagccgtcgg cgcgggccgc ctcctcggtg cggcccaccg cgcagatctg
     5881 cgggtcggtg aagacgacct ggggtgcgcc gtagccgccc gccaggtcgc gcatcgcggg
     5941 cagctcgtcg ccccgcgccc gcgccgcgat cacgtcgccg cagatcctgg cctggtactt
     6001 gcccatgtgc gtcagcagca cccgcccgtt gacgtcgccg acggcgtaca gccagccgcc
     6061 ctcgaccccg gtggcgcgca ggctgtcgtc cacctcgacc ggccggtcct ccggcaggcc
     6121 caccgaggcg agccccaggt tgcgggtcgc ggggtggcgg ccggtcgcca ccagcagctc
     6181 gtcggcctcc agcggcggcc cctccggcag gtgcacggtg accttcccgc cgggctccgg
     6241 ccgctcgacc cggacgacgt cggtgtgggt gcgcacgtcg atgcccgcct cggcgaacga
     6301 ctcggcgagc agctcgcccg cgaacggctc catgcggttg agcagcccgc cgccgcgcac
     6361 cagcacggtg gtctgccggg cgccgagccc gtgcatggcc tgcgccatct cgcaggcgac
     6421 cacgccgccg ccgatcacga ccagccgctc ggggatcgcg gtcgccgccg tcacctcgtg
     6481 gctggtccag ggggccgcct cggccaggcc gggcgtgggc gggatggcgg cggtgctgcc
     6541 ggtcgccagc acgacggcct ggcgggcggt cagcacccgc tccgcgccgt tctcccccgt
     6601 cacgaggacg cgcttggggc cgtcgaggcg gccgcggccg cggacgaact cggccgggac
     6661 gccctcgacc cagcgcacct ggccggcgtc gtcgtagccg gagacggcct cgtcgcgcct
     6721 ggccagcacc ttggcgacat cgatcgggcc gagcgacagg ccgggcaccc gcgccacctc
     6781 gcccgccagg tcgatcggcc gcagcagcgc cttgctcggc acgcacgccc agtaggagca
     6841 ctcgccgccg gccagccgct cctcgacgat ggccgcggtc aggccgcccc gcacggcgcg
     6901 gtccacgacg ttctcgcccg ccggccccgc cccgatgacg atgacatcga actcgtcagc
     6961 cacccctgcc tccacaagac tcgttcggct atcgagaaga tgctttcacg gccgatcggc
     7021 gccccgcgaa cccggccccg aggcgcgggt cacccccggc cattcgcccg cacgtagggg
     7081 cggcgtcgaa gtccgttaac ccgcgcgccc tagcgtgccc gcatggcgga tgactacccg
     7141 acttcggtgc cgttccggca ggcgacggac ggctaccaca cgttccggat cccggcggcc
     7201 gtggtgacgc gggccggcac ggtgctggcg ttcgcggagg ggcggcgcgg gtcggcgtcc
     7261 gactccgggc acatcgacct ggtgctcaag cggtcgtccg acggcggccg gacgtggggc
     7321 gggctccagg tggtggcgac ggagccgcag cggggcacgg cggggaaccc ggcgccggtg
     7381 gtgctcgacg acggccggat cctgctcgtc ttcgtgcggc agggcccgtc ggccaccgag
     7441 gagaagatcc ggcgcggcca ggtccccgcg gcggcagggc ggcgggtgtt cgcacaggtc
     7501 agcgaggacg acggggccac gtggtcggcg cccagggaga tcaccgggag cgtgaagaag
     7561 cccgagtggc ggtggtacgc gaccacgccc gggcacgcgg tccagctccg gcagggcgag
     7621 cacgccgggc gcgtcgtcgt gcccgccaac cactcgctgc cgcccagcgg gcaggacaac
     7681 ggcaccgagg gcaagtacaa cggcggccac gcgctgctga gcgacgacgg cgggcagacc
     7741 tggcgcatcg ggtacgtcga cgacaacccc gacggctacg tcaacgtgaa cgagaccacc
     7801 gccaccgagc tgcccggcgg ccggctctac ctcaacaccc gcaccgactc caccgccccc
     7861 ggcaccaggg ccgacgcctg ctcggccgac ggcgggcaga cgctggagct gccgttccgc
     7921 ccgcaggccg ggctcgccgg gccggtggtg gagggcagcg tgctgtggtg cgacgagccg
     7981 gaggtgctgc tgttctcggg gcccgcggcg cccgacgcgc gggccctgat gaccgtgcgc
     8041 gccagccacg accacggcgt cacctggcgg gtggcgcaca cggtgtcggg gctgcccgcc
     8101 gcctactccg acctggtgcg ggtggacggc gagacggtgg gcctgctgtt cgagacgggg
     8161 aacttcggcc cgtacgagag catcgccttc cgccggatcc cggtcgcgga gctggccgcc
     8221 cgctgagggg agccaacggc cggccgggcg ctgccgggag ccactggccg gccgggcgct
     8281 gggggagccg ccgggcggct gggcgcgcgt aagctgcggc ggtggacacg gaagcggtgc
     8341 gatcgttcgt ccgggcggcg gagctcggcc agttccagta cgcggccgac gagctgggcg
     8401 tgacccagca ggcggtctcg aagcggatcg ccgccctgga gcgcgagctg gaggtgcgcc
     8461 tgttcacccg caccgcccgg ggggtcgagt tgacgcccgg cggccaggcg ttcctcccgc
     8521 acgcgcgggg catcgtcgcg ggcgtcgagc acgccatggg cgcggtccgg cccgacgcgc
     8581 ggctgctgcg gatcgacgtg ctgggcttcc gcagcgcgca ggccgtcgtc ctgcacgact
     8641 actggcgctc gaaccccggg atccagctcg acgtggtcgc gttgaaggcg ggtgaccccg
     8701 ggacggcggt cgcggccgtc cgggcgggcg aggtcgacgc ctccttccgg gccgtcaccg
     8761 acccggccgc gctgccccgc gacgtcgaga tggcccgggt gctcgacgtc cccttggagc
     8821 tgctcgtggg gccggggcat ccgctcgccg ccgcccgtac ggtgacgccg gagcagctgc
     8881 gcccgcaccg gatccggatc gcgggcctcg cgccgcgcag cgagtgggcc gacttctacg
     8941 accagctcgc caccgccttc ggcctgcgca tcgacgggga gggccccaac ttcgggatcg
     9001 agcccttgct cgacacgctc gcggagtcgg gtgacgtggc cacgctcgtc ggcgcccgcg
     9061 accggctcgc ctggccggcc ggccacgacc tgcgccgcat cccgatcgtg gaccccgtgc
     9121 tcgcctaccc gcacgcgctc ctcatgccac gggcgaaccc gcacccccgg ctccggccga
     9181 tcattgacta cttccggagc ctggcgggcg cgcccaggac ggcctgggtg ccgtcctggg
     9241 ccacgtcacg ccgctagggc tcgacgacga tgacctcgta cgtcggcgac gtcggcggga
     9301 tcgtgccgag gtggccgttg accaccgcga gccggtgacg gtcgatgagc gcggccgtgg
     9361 tggggaagtc gaagagcggg ctggtgatcg tcttctccag cacgccgccg gacaggtcgt
     9421 ggctcaggcg gaagcgggag acctggctgg tcgagttcac cacccaaagg cggtcgccgg
     9481 acaggacgag gccgtcgggg ctcggcacgt ccaccccggc gatgggcgtg ctggcgccgg
     9541 tggcgggatc gaccgtgtag agccggccga ggccggtgtg ggcgacgatg ggggtgcggc
     9601 cggcgacctg gatgccgttg aggttgacct cgccgctggt gtcggcggcc gggccggtga
     9661 ccgtgagcgt gcgggcgggg ccgagccggc ccttgtggcc gatcggcacg aagtacagct
     9721 cggcccgccc ggagttggtg aaccacacgc cgtcgcggcc cagggccgcg tcgttgatga
     9781 gccccgcatc gggcgcggcg agctggtacg tggccacctc cactccggaa cgcaggtcgt
     9841 agacgtacgc ctggccggtg aagccgcccg cgacgaacag caggccgtgg cggtgatcgg
     9901 cgaccatgcc caccgccatg cgcccgtcgg gcgcgtcgat gaagcgctcg gcggtgccgc
     9961 gccgggcgtc gccgcggaag atgtcgccgc cgaacaggtc gccggcgtag aaggtgccgc
    10021 ccggcccggc ggcgatgccc tcggcggagg tggcgccggg caggacgatc acgttgtcct
    10081 gtgccacggc ggcggcggcg ggcgcccacg cggcgaccgc gagggccggc acgaggagca
    10141 gcctcaggaa taaggaacga cggggtttca cacgcatgcg catctcctag ccgtcggagt
    10201 tgaccacgtt catcaccatg atgaggccat gaacggtgtc gtcctccgtg cgcaggtgtg
    10261 agagctgcac ggtgagcggc gcggggcggc cccggcggtt gaccgcgtcg agcaccagcc
    10321 cctccacctc caccagcggg ttggtgccgt tggcgagcgc ggcgcgcagg cgcggcagga
    10381 gcaggtcgag gggcaggccg atgtcgagcc cggccagcgg ctcgcccacg gcctcgtcgg
    10441 agcgcacccc ccacagctcc tcggcgcccg ggctccagac caccacgcgc aggtcgtcgt
    10501 cgagcaccac cacggcgtcg ccgaggctgc gcaccaccga ggagacgaac cggttgacct
    10561 cgtcgagctc gatggtgcgg gcggtcaggg cgtcgttgat gtgctggagc tcgtcgttgg
    10621 tggactggag ctcctcgttc atcgtctcca gctcttcgtt ggtggactgg agctcttcgt
    10681 tggtggtttc cagctcctcg ttcgtggact ggagctcctc gttggtggtc tccagctcct
    10741 cgttgagcga ctgcagctcc tcgtaggcct gctcgagctg ccggttggcc tgctccagct
    10801 cgtcgcgcag cttgcggtag cgcgtgacat cgtagaagtg gatacccatc ccgaccagat
    10861 tgcccgaggc cagcaggggg acgaccgaga cgtcgaagac gctgggctcc ggcgacccga
    10921 cgcggtgcca gacgacgtcc tgcagctcca ccgggcgcag gtcgtggcgg gcctgctcga
    10981 tgaccgagcg cagctccacg gggcggtagg agacctcaag gtcctggaag gggcggccga
    11041 cgtcgcgcgg gttgaggttg aacagcgcct cggccttgga gttggccagc gccaggttgc
    11101 ccgagacgtc gacgacgagc tgcgccaccg ggccggacgc cagcgccacg gacgccagcg
    11161 tcggcagccg cgaggccagg tcggtggcgg cgccggtgac cgaccacggg gcgcggtttc
    11221 cgtggttggc cggcctgatc ttcctgaaca ggcgcatgcg caggtcgacg ggctcgaact
    11281 tgtcgctgtg gttgagcagc atctccgcct tgcccaggaa caggaacccg gggtcggaca
    11341 gcgcgaagtg gaagcgccgg atgatgttga gctgcatctc cgtgttgaag tacatcagcg
    11401 tgttgcgggc cagcagcagg tcgacgcggg agatgggcgc gtcgtgggtg aggtcgttgc
    11461 ggccgaagat gagctggcgg cgcaggtcgc ggcggaaggt gtagccgttc tcgacccgct
    11521 cgaagtaggc ctcgcgcagg tcgatcggca cgtcggcgag cgcccggtcg ttgtagacgc
    11581 ccgtgcgggc gacgtgcagc gccttctcgt cgaggtcggt gccgtagatc ttcacccggt
    11641 cgcggaaccc gtccatgccg agctcttcgg ccagcaccat ggcgatggtg taggcctcct
    11701 cgccggtggc gcacccggcg ctccagatgc ggatgggctg gcccgccggc ttctggtcga
    11761 gcagggcggg gatgacgagc tcgcgcagcc gctgccacgc ggccgcgtct ctgaagaaac
    11821 tggtgacatt gatcaagaga ctgtcgaaga gtcgggtgaa ctcctcaggc tccaactcca
    11881 gtagatcgcg gtattcgccg tagtcgtgca gcttgagcgc ctcgagccgg cgggcgatcc
    11941 gccggatcaa ggtgttgcgc ttgtagcccg tgaagtcgaa accgcgcgtc tccttgagga
    12001 gaaggaggag gtcgtcgaac tcacgctctt cctctgtcgt cacaacggaa gcctacgccg
    12061 atcgaccctg ctcagtccgc cagcagcgtg tcaccattgc gaccgatgcg cgattgcagc
    12121 atgcgaatgg tgttcagtgc ctcgctggtg cgttcctcct cctcgtggaa gtaacgcagc
    12181 gacagctcct ggccccgctc ctcggcggag cggcgcatgc gctccagcac ccgcagccgc
    12241 tcctccagcc gctggatggc cacccacagg gcgcgctcga cggcgtcgga ctgcgcgttg
    12301 atcatgctgt cgcgcgacca ggcgtggccg acgcggcaca cgtaccggga ggatgtggcg
    12361 ctcttctgct cgtagatggg gccgttgcac tccgggcagc tgaacgcgat cagttcccct
    12421 tccggctcgc ccagggacgg cgcctcgcgc aggaactgct cgatctcgcg ctccatctcg
    12481 ttgtcgtaca cctggacctc cgtactcaca ggggtacggc tctgctccag gacccacccg
    12541 gccagctcgc gcacgggcag ggcccgcgcg gccggcaccg ccgtcatggc ggctcgcggc
    12601 atgccgggaa acgcgcactc cgcaagatcc tgtacggcga ccgcaccccc gtgcttgtag
    12661 atcgcctcgc accctctcgc cccgtcgtcc agggtgccgc tcagcaccac ggccgccacg
    12721 cgcgctcccg cgtcgagagc cgcgctcacg aacagcggat cggccgccgg gcggtgcccg
    12781 ttgtgctgcg ggccgcgcgt cagccggatc atgccgtcgc tcatgagcag gtggaagtcg
    12841 gggcgggcga cgtacacgcg gccaggacgg atgatctcct ggtcctcggc gggggccgcc
    12901 ttgagcggcc cggcccggtc gaggatgccg gccagcctgc tgctgccctg cggcggcacg
    12961 tgcagcacca ccagcaccgc cgccggcagg tccgccggca gctcgctcag caggacccgc
    13021 agtgactcaa cgccgcccgc cgatgcggcg accacgacca cgtcacgtcc tggagcctcc
    13081 atgtcccccc tctatcccgg atgagaggcc tcatgcgcgc tcaggacaga tggggccgct
    13141 cctggctcgc ctcggccagc gtcaggatcg agcgggcttc cgacaggctg ctgcgcatgg
    13201 ccatcaggct gtcgtcgcag cgccgccggg tcgtcaggag ccgggcgcgg gcctgggccg
    13261 cggcggtgag ccggttgttc agcgcctgct gctggtgcag cgcctggtcg cgcagcgagc
    13321 gcgcctcgaa gatgaccgac ggcaggctgc tcacgtcgag ctcgatctcg gccgcgctcg
    13381 ggcgggcggc ctgggcggcc tgggcggcct gggcgggcgc cggctcgcgc cgcgacctgg
    13441 cctgcgcccg cacgggggac ggagcgcgcg gcacggtgcg cagccggggc aggtggcggc
    13501 gccgcagcgc cggctcggcc ggttggtacg cctccacgcc cgccgccgcc agcgcctcgg
    13561 ccatcgtggc gaacaccggg atcgtcgccg ccgactgctc ggtcatcagc gcgatgaggc
    13621 ggcgcagcgg cggctgcacc tccgccaggg ccaggtgacc gcccttctcc tgcagcgcgc
    13681 gatgggtgcg cgcgagcagg tcgaggccgt tgaggtcgca gaaccacaga tcgcccgcgg
    13741 ccaccagcac gtgcttcacc gtggtctgcg gcagcgggtc gaggaaggcg gccagcacgg
    13801 gtttcgtcgt cgagtcgagc tctccggtca gcgcgatcac cagtgtggtg tcgtcgacgg
    13861 gcaccaggcg tacggacagc tgcatcatgg cgagccccct ccctctgggt cggcgcgcct
    13921 tcggggacgg tcgcgcgcgg cagattgcgg ctcgaacccc atcttcccgc tccaccgccc
    13981 aaagagccag aagattgggc tcacgcgtgg ctgtgcgcgc cgagataatt cggcagaccg
    14041 gtccagctgt cgcccggcgg agcgccgtcc aggcgggcca ccaggtgggc cttgaccatg
    14101 agacgcgcgc cgaagagcgc gcccctggcc gcccgtacgt cgggggtgtc cggcagcgcc
    14161 gcgaacgccc gcctggcggc ggcggccacg acctcccaca gccggtcctc ggcgtccctg
    14221 tcgccctgcc cgaacagcgc gatcaggctg ccgaacgtgg tgccggccag cgagccgaac
    14281 agcttggcgt gcagcaccgc cggatcgtcg ctgagcagcc tggggctgac cggcggcacc
    14341 tcgatcccgt gccgggccag ccgggcgggg ctgatccgca cgtcggccag atcccggtag
    14401 accagccggt acggcaggcc gtccgcgccc agcgccacca gcaggttctg cccgtgcgcc
    14461 tccagcgcca cgccgagcgc cagcagcccc agcgtgtccg tcagggccag gcgggcgaac
    14521 gcggccagcc aggcggccgg gtcgctcacc atggagcggg tgacggcggc gaccggcagc
    14581 accgtgcccg gctcggccgt gggctcgcga agcatgcagg acaggtcggc gctgtgccgg
    14641 cccgccacct ggccggcggc cccggccagg tagcgggcga tgcgcagggt gccgccgcac
    14701 ttggcggcca gcgtggtgag caggtccgac agcgggacgc agtcgcggac cgagccgggc
    14761 gagatgtccc tgatccccga ggtcatgcgg gtggtgaagg cggtcttgag atgcgggccg
    14821 ccgtcgagcg gggccagcgt gcgtacggac atgagcgggc gggcccggac gacgcccgtc
    14881 gcgtggggac gcaggcccag ggcgggcagg acgtgccggg tctgccacgg gtgcacgggc
    14941 agcagcagcc ggtcgccgtc cacgagcgag gccggccacg gccccgtgac caggcattcg
    15001 cgcagcggca gcgccaggag gtcgagggcg acggtggggc ggtgctcggg catgtacgcc
    15061 agctgctcgg ccaccgacac gccgggccgg ttgcggcagc ccggatggta cgggtgcccg
    15121 tccaccacgc tctgctcgtg atcctccacg gtgtcgccgg gccgcgggga ggcgccggcg
    15181 cgcgacagcg ccatggaggc cacgctgtgg tcgaggtcgt ccacgaggcg ggccgagccc
    15241 ggcagcccga gggcggccag cagctcggcc ggatggcggt acgggcggcc ggccagccgg
    15301 agctcgggtt cctcccgcag gtcgtacggc cgccgctccg ggcccgtcag ctcgcggccg
    15361 tcggccagca acacgcggga cgggccggtg gcggtcaggc gggggagggg ttcgtacagg
    15421 agccctcgcc acagccgccc caggacggcg gctcgcgcgc cgggcagggc cgccgtgtag
    15481 cggtccgaca ggtcgggccg gacgagagcc agttcggcgg cgaactcgcc ctctaaacgc
    15541 ctcatatctc tcatctttcc cagaaacccg cctgatagct actctgtggg catcaatggg
    15601 gacaaagggt aggagtaggg tcgccatggc attcactgac ggcctcctgc ccgccgcagg
    15661 gccggggctc gaagccgagt cccttgcggt gacggcgctg ctgaactgtc tcctccgcga
    15721 agtcgccacg cccgccgacc cctcggctcc tgccggcccc gtcgcgtccg ctgagccctt
    15781 cgcgtccgcc ggccccttcg cgcccgccga gcctcgcttt tttgtgctgc ccgcgaccgg
    15841 gcatgtgctg cgtgtcggtg gtgcccggtt tcccgccgag cccgccctgc gcacccccga
    15901 cggctggcgg ccgatcccgc tgccggagct cgtcgagctg accgccgccg agctgcgggc
    15961 cgccaccggg gccgccaacg acgcgctgcc cggcgagatc ctcgacagcc gggacgtcac
    16021 ggccgtcctg ctggcggcca ggcgtgccac ggtgccgccc gccgacgcgt acctgcgctc
    16081 cgagcaggcc ctcgtcgccg gccaccgcta ccaccccgcg cccaaggcca ggggcggcgg
    16141 cgggcccagg gagtggctgc ggtactcgcc cgaggcgcgg gcgagcttcg ccctgccgct
    16201 gctcgccgta ccggcggacg acctggtggt ggacggggac gcgagcgcgc tggaccgcct
    16261 cggccccgcg ccgggcgccg gcctggccct gctgcccgcc cacccctggc agctcgaact
    16321 gctgggcgag accggcctgc ggcaggcggg cgtcagcgcc gccacggcgg tggccaccgc
    16381 gtccatccgc acggtgtacc tgccggaggc ggacctgttc tgcaagttca gcctcgacgt
    16441 gcggatcacg aacgacgtcc gccgcctgtg gctgcacgac ctgcgccgcc tctcgctcgt
    16501 cgcggccctg gtggacgtgg ccttcgacga cctgccgtgc cacctgcccc gcccggccgt
    16561 gctgcgcgac cggggctggc gcagcgcccg gctgggcggc gacgggggtg aggggctggc
    16621 cgtgatcgtc cgcgacgggc tgggcgagca cctgctcccc gggctgaccg cgctgctggc
    16681 ggcgggcatc agcgagggct tccccggcaa cccgatcgac ggcctggacg aggacggggc
    16741 gctcgtgtgg tgggagcggt atttggaaca tgtggtgccg ccggtgctgc acgcgtattt
    16801 gaggcacggg gtcgtgctcg aatgtcacct gcagaacgtg ctggtcgcgg tggacgcgca
    16861 cggactgccg gggcaggcgc tgttccgcga ccacgagggc gtcaagctgg tcgccgagcg
    16921 ccatcccggg ctcaccgcgc ccgtgctggg cggcgtacgg gcgtgggagc ggctggtcta
    16981 ctgcctgctg accaacaacc tgtgcgagat cgcgggcgcg gtggcggagc ggcatccccg
    17041 cctggtcggc gagctgtgga cgcgggccag ggccgtgttc gcggcggcgg ccaaggagta
    17101 cggcgacccg ccggagctgc gcgacctgct ggccgccacg cacatcccgg ccaaggccaa
    17161 cctgctgctg cgctggctgg acgccgacgg cgcggccatg cggtgggtgc cgatcccgaa
    17221 cccgctgcgg ctgttcgcac cctgatcgct caagagcaca tcctgatcgc tcaagagcac
    17281 atcctgatcg ctcaagagca catcctgatc gctcagagca cgtcctgatc gcctcagggc
    17341 acgtcctgat cgatcagggg cgctcctgga gccaggacgg cggcgcctgc tcggcgtcct
    17401 cgtggtgccg cttcttggac ggccgcggcg cggcacccac cacgatgccg tacagcacgt
    17461 ggtcggccag cagcgccacc cgctcggccc gcccgtgccg gcgcgtcagg cccagtgcgg
    17521 gcgcgatcgc cgtctcgaag gcggcccagg ccagcacccc gtagacgggc cccgcccagc
    17581 gccgccggcg caccgccttg ggcaggaggc cgaagaacgc cccgccgacc gccccgtacg
    17641 tccagtgcac ggcctccacg acggccggcc gccgctcgtc cggcacgctg tggaaggctt
    17701 tgggcgcggt ccgcttgagc acggactcgg gtggcgtgct cggcaccatg ccgagcgcgg
    17761 tggtgagctg ccgcaggccc gacatcgcca tggagccgat cacgcctctg gcggccgccc
    17821 gcacgatcgg cctgcgctcg cgttcgggct gaacgtcctc gcgcaggtgg gcgggcttct
    17881 gcagggtctg agtcatggag tgccgcctac cgaacggcgc gcgggctaaa cctcctcggg
    17941 cagcgagcgc atccgtccga tgatggcggt cgtggagcgg tccggcaggt agccgagcac
    18001 ccgcacctcg ccgccgagcg cgcgcaccag cggcgcctcg ggcagcatct ccgccgtgta
    18061 gtcgccgccc ttcacgtaca gctcgggccg catcatcctg atcagccgct ccggcgtgtc
    18121 ctcgtcgaac tcggtgacgt agtccacgtc gttcagcgcg gccagcaccg acatccggtc
    18181 ctcgcacgag ttgaccggcc ggccggggcc tttcagccgg gccacgctgg cgtcgctgtt
    18241 gaccgcgacc accagcacgt cgccgagctg ccccgcctgc tccaggtacg tcacgtgccc
    18301 ccggtgcagc acgtcgaagc agccgttggt gaacaccacc cgctcgcccc tgcgccggtg
    18361 ctcgtcgagg agctgggcca gccgctcggc cgtctgcacg gtgccctcct ggcggcgcag
    18421 tgcgcgtacc aggtcgtagc gggtgcagac ggcggtgccc tggcggcgca cgacgacgcc
    18481 ggccgccgcc tgcccggcct ccgccgcctc ctccggcgag gcgccgctcg ccagccagag
    18541 cgcgaacgcg gccgtgtacg tgtcgcccgc gcccgtcgcc atgtgctgcg gcgcgggctg
    18601 ggcgtaggtc cggtacggcg ggtggccccg gcggtgcagc agcgtgccct cgccgtccag
    18661 cgtggtgacc acgatcccgg cgccggtcag ctccagcagc cgctcggagc ggcccatcag
    18721 gtacgcgggc cggtccacgg cgccgccgtc gtcgccgagc agccggacga cctcggcgta
    18781 gttgggcagc acggcggccg gggcgcactc ccgccacggc gcgaccgcgt gcgcgtccac
    18841 gaccagaagc ggcagccccg ccagcgcccg ccgcacggcc ggggtgcaca cgccgccgcc
    18901 gtagtcgcag gccaccacca cgtcggcgcc cgcgacggcc tcctcgaccc gcgcgagcag
    18961 gtcgcgctcg gcatcctcgg ggatgacgga caggtcctcc tcgtcgtagc gggccgtgag
    19021 ctggccgctg gtgaccagcc ggcgcttgtg cgcggtgcgc cgccccggca cggtcagcag
    19081 gtcggtgccg acgccgagca gccgcagcgc gttgtccagc ttctccccgc actcgtcgtc
    19141 gcccaccacg ccgacgagcc ggacacgggc cccgagcgcc accaggttgg cggcggtgtt
    19201 ggcggcgccg ccgggggcgt cctcggtcgc ctccaggctc atcacgggca ccggcgcctc
    19261 ctgcgcgagg cgcttggccg agccgtgcag ccacgagtcg agcatgacgt cgccgacgac
    19321 cacggcgttg atgatctcat ctgtgcccat gaggagcgtg tacctgcaaa agaccagctc
    19381 aaaccctata taagggaagt tacggacgct gagggccggg tagccaggcc gctatgcacc
    19441 gcccttcaga cctcgacgtg ctcgtcccga ccagggaccg gccggccgcg ctcgccgtga
    19501 cgctggccgg gctggcggcc cagagcgccc gcgggttccg ggtcgtcgtc tccgaccagt
    19561 cggagatgcc ggtcaccggt gacccgctgg tcgcgagcgc cgtacggatc ctggagcacc
    19621 tcgggagcga ggtggcgctg ctgcggcacg tccccgcgcg cgggctggcc gagcagcgcc
    19681 agtacctgct ggagcaggcg ggccggccgc tgtgcctgta tctcgacgac gacgtgtggc
    19741 tggagcccga cgccgtgggc gtgctgctcg ccgcgatggc gcagctgcgg tgcgggttcg
    19801 tcgggtacgg gctgcacggg ctctcctacc gcgacgaccg gcggcccgac gagctggagc
    19861 cttacgagga atgggcccgc gaggtgtggc ccgagcgggt ccgcaggggc agccccgcct
    19921 gggggcggca cacgctgcac aacgcggcca atccgctgca cctggccgaa cgggtggggg
    19981 cgcggctggc gtggcaggcg tacaaggtgg cctggatcgg cggctgcgtg ctctacgacc
    20041 gggagcggct ggaggagtgc ggcgggttcg cgttctggcg ctcggtgccg cccgcgcacg
    20101 ccggcgagga cgtcgtcgcg caactgcgcg tcatggagcg gtacggcggc gcggggctgc
    20161 tgcccagccg cgcctaccac ctggagctgc cgaccaccgt cgtggaccgc ggcgcggaat
    20221 gctacgacta cgtgctggac cgagcatgaa ggcacccgga cctgacacga gggcgctcat
    20281 cggggacgtg cggcgcatcg cggtgctgcg ggccaacgcc atcggcgact acctcatggc
    20341 cgtgccggcc ctggaggcgc tcaaacgcgc ctaccccggc gcccgcctga ccctgctcgg
    20401 caccgcctgg cacgccgcct tcctcaccgg ccgccccggc cccgtggacg acgtggtggc
    20461 gctgccgccg atctcgggcg tctccacccg cgagccgggc caccgggcgc cggaggagct
    20521 gtgcgagcgg ttgcggcagc gcgagttcga cctggcggtg cagatccacg ggggcggccg
    20581 gttctccaac ccgttcgtgc gccggctggg cgccagggtg accgcggggc tgcgcgcgcc
    20641 gggggccgag cggctggacc gctgggtgcc gtacaccgac tatcaccacg agaccctgcg
    20701 cttcctccag gtggcggcgc tggtcggcgc cgtggacggc gggctggagc cgcgcgtggc
    20761 ggtcaccgcc gccgaccgcg ccgacctggc ccgcgcgctc gggcagccgc ccgccgggct
    20821 ggtggccgtg cacccgggcg cgaccgaccc gcgacggcgc tggccggtgg agcgcttcgc
    20881 cgaggtggcc gatcagacgg gccgccccgt ggtcgtgacc ggcacgcgcg atgagcagga
    20941 cctcgtgatg ggcgtggtcg aggccatgcg ccggcccgcg atccccgtcg tgggcgcgct
    21001 cggcctcggc gggctcgccg ccctgtacga gcgctgcgac ctcgtgatcg ccaacgacac
    21061 cggcccccgc cacctggccg ccgccgtcgg cacccccacc gtcgctatct actggtgcgg
    21121 caacctgatc caggccggcc cgctcagcag gaccgcgcac cggcccctga tctcctggac
    21181 caccgcctgc ccgcgctgcg gcgccgccgg cgtggacccg gccgccgagc gctgcccgca
    21241 cgacgagtca tgggtgcgcg acgtcaccgt ggacatggtg gcggagcagg tggacgacct
    21301 actgaccaag ggggaccgat gagcggacac gccgtgctcg acgagctgcg acaggccatc
    21361 gacgaggtgt tccacggccg cgaacgggtg gcgatgcgcg acgtctacgc ccaggcctcg
    21421 cggcacgtga acctttccgc cgacctgctg acccacctca acgagctgcc cgaaggcccc
    21481 tacgaccggc gggagctgac cgaggcgatc aacgaggtga tcacccgcag gggcgagcag
    21541 gacacgctgg gcctgctgga ggtgccccag caggccggcg cggccccgct ggagtacgtc
    21601 aaccccaccc cgaccgtccc cgacgagaac gagggccccg acctgatgcg ctagaactct
    21661 tgtcgatcca ggcatagcgg gagcaccacc ggggcgtctg agagggtgat gtcgattccc
    21721 tggaggtgac cgtggacgcc gcggacgagc aacggttccg cgagttcgtt gacgcgcgtt
    21781 ctcccgccct catgcggctc gggtacctgc tcaccggcgg tgaccagcac gcggccgagg
    21841 acctggtgca gaccgcgctg gcgaggctgg cggccaagtg gcggcgggtg acggcgcccg
    21901 aggcgtacgc caagcagatc atgtaccggc agcaggtcag ctggtggcgg gcgagcacgc
    21961 ggcggggcga ggtcttacag gccggcccgc ccgaacggga ggcgcgcgac gcgcaccacc
    22021 agagcgagct gcgcctcgtg ctgcgctccg ccctcgcccg gctcaccgcc cgccagcgcg
    22081 cggtggtggt gctgcgttac tacgaggatc tgcccgagca ggaggtggcc caggtgctgg
    22141 gctgctccgt cggcacggtc aggagcaccg cgcaccgatc gctggcgcgg ctgcgcgaga
    22201 cggcccccga gctggccctg gagctggccc gcgacctgga ggtgaccacg tgacccggct
    22261 gctgcgcgac acgctggagg actgggcggg cgaggccagg gtgccccccg gcctggccga
    22321 ccgggcgcta cggaggcgcg cctggaagcc ttacggggcc gccgtgctgg tggcggccat
    22381 gatcgcggcc gtcgccgtgt tcgtcaccgt gcaacgcgac cccgtgccgc ccgtcgcccg
    22441 cccgctcagc ggcatcacgc tgccgccccg gccgtcgccg gcgccgacgg acatccgcac
    22501 ggacaccgag cacagcccgc ccgccaagct cgtcgccgcc gggcggatgg cggtgtcggc
    22561 gtactacgtg acccggcagg agccggtcga gggcgaccgc acgcgcgtcc ggcgcacctg
    22621 gtccgtgtac gacccgggca cggacggcta ccgcgagacc ccgtacgcgt gggtggacgt
    22681 cgcgccgggg ctgcaggtcg cggccgtgat ccaaggggac ctgatcggca accgggtggg
    22741 cgtgctcaac ctcgacacgg ggcagatgct ggccacgtac gagctggagc acccggtggg
    22801 atccgtcgtg tggtccccgg acggcaccag gatcctcgcc accgcctact ccagctaccc
    22861 cgatgtcttc caggaggaca gcgccgagat gggcagcccg cgcaccggct actacgtcat
    22921 cgacacgggg acgggcgagt cggtctacca cgagctgccc ccgctgcccg acggcatcta
    22981 cagcgacgcc gagtacacca acggcaacgg ccgccaggac ctcggctgga gcctggacgg
    23041 cgagctgatc tggggcccca cctcctcctc gcccgacagg cgcttctaca ccctggacgg
    23101 ctcccccacg gacgcgccca agggggagcg ctaccggcgc ggcagcggcc tgtcggccac
    23161 ctctcccgac ggccagctgg tgctggggga tgacggcatg cccacgaaga tcaccgaagc
    23221 cgcgacgggg aaggtcgtcg ggcggcagcg cgtcctgcaa ctgcacgcct gggccgacaa
    23281 cgacaacgtc ctcgccctgg gctgcgccgg gaagtgcgag aacgagttca acaacggtct
    23341 ggtgctggtc agcgtggacg gctcgaagac gatccagctc gccgccaacc gcgacagcga
    23401 cgccgacggc tcctggcgct gggtcctcac cccgagataa ctgcttgtct ccggacgatc
    23461 cgctcggata ggaagcatgc gtgctgaaag gcaagaaaat cgggctcagg gcccgccatg
    23521 aggacgatat tccgatcctg ctgaccgagc tctacgacga ccccgtcaac tcctcccgcg
    23581 ccgaaggcgg gccctggcgg ccgatcacgc ccggcacgaa cgactcgcgg ctcgtgccgg
    23641 acgacaagga ccagtcgaag gtcccgttct cggtcgtgga gctcgacggc gggaccctgg
    23701 tcggcagcgc caacctgtgg gggatcgaca cccacaaccg gtccgcacac atcgggctgg
    23761 ggctgctgcc gtcctgccgc ggcaagggct acggcagcga cgtggtggcg acgctgtgcc
    23821 actacgggtt cgtcctgcgc gggctgcggc ggctgcagat cgagacgctg tccgacaatt
    23881 acgcgatgct gcgggccgcc gagcgcaacg gcttcgtccg cgagggcgtg ctgcgctcgt
    23941 cggcgtgggt gctgggccgc ttcatggacg aggtgctgct cggactcctc gccgaggagt
    24001 ggaagccgga cacgccgagc taggcactgg gagctcagat gaggcccgcg tcgtgggcga
    24061 ggagtgcgat ctgggtgcgg ttgtccaggt cgagcttggt caggatgctg gagacgtggg
    24121 ccttcacggt cgtcacgccc atcacgagat cggcggcgat gtcggcgttc gtccggccct
    24181 gcgcgatcgc cagggccacc tcgtgctcgc gcggcgtgag ggccgccagc gcggcgcggg
    24241 cccgctcgta ggcgcccgcc tgggcgatcg tgcgctccat caaccggcgg gtgatgtgcg
    24301 gggacaggat cgggtcgccg gcggagacac gggtgatcgc ctccacgatc cgcggcggcg
    24361 gcgtgtcctt gagcaggaac ccggcggcgc ccgcgcgcag cgcgtgcagc acgttctcgt
    24421 cggtgtcgaa cgtggtcagc acgatcacct cgggcggccg cgcgcgggcc cgcagcctcc
    24481 gcgtggccgt gatgccgtcg aggcgcggca tgcgcaggtc catcaggacg acgtcgggcg
    24541 cgtgcgcgtc ggtggcggtg atcgcctcct ggccgtcggc cgcctcggcg acgacggtga
    24601 tgcccgccgc tccgtcgagc atcatggaca gcccggcccg gaccagggcg tcgtcgtcga
    24661 ccaggaggac acggatcacg gcggccatgg taaccgagcc cgcagcacga actccgcgcc
    24721 ggtgccctgg tggtcgagcc gcccgcccgc caggcgtacc cgctcggtca gccccaccag
    24781 gccgaggccg ctgccgggca cgatcggcgc ggtgcccggc gggggcagcg ggttgcgcac
    24841 gtcgatcagc agcggtgtcc ccggcgcgcc ctccagcagc acctccaccg gttctcccgg
    24901 cgcgtgcttg cgggcgttcg tgagcccctc ctgcacgacc cggtaggcgg tacgggacac
    24961 ggccggcggc agggacgtgg tgccggtgat gccttcgcgc aggcgtaccg gctggcccgc
    25021 ctcccgcgcc tccgcgacca ggccgggcag gtcggccagg tccgggtgcg gttcgaggtc
    25081 gtcaccctcg tcgtcctgct cgcgcagcag gacgatcacc tgccgcagct cctccaacgc
    25141 ctggtgcacg cccgtgcgca ccaccccggc cgccttggcg atccggtcgg gagaggcgtc
    25201 cggacggtac tccagcgccc ccgcgtgcgt ggccaccagg gacaggcggt gggccagcac
    25261 gtcgtgcatc tccctggcca gccggtgccg ctccgccatg cgggcctccg ccacccggcg
    25321 cccctgctcg gcctccgctc tggcggcccg ctcgcgcagg gagatgagca gggcccgccg
    25381 cgaacgggcc agcgcgcccc agcccagcaa cgcaccgtac gcggcgcaga tcagcagcaa
    25441 ccaccagccg aacgagatgc ccgaattggg ccgccacaac ccctgcacca ggtgagccgc
    25501 catgcccgcg gccgtcacgg ccgccgccac ggggaaccgc ctgcgctgcg ccacctgcaa
    25561 cgcgcccgtc gtcgccgccg gcgtggccgc cggggagagc gtggccagca cggtggcggc
    25621 cagcgccccg tggaccggcc agcggagctg ggccagcgcg gcgaccaggc tcaccgccgc
    25681 caccgccacg tccagccacc acgtcggccc gacctcccga tcccacagac tcacggtgct
    25741 cagcgcgccg atcgtcaggc ccacggccgc caccgccagc gggtgcgagg ggcgtatctg
    25801 actcatgcgg ccaggctaaa cggggggctg gcggggccgg cacctacgaa agtaggagcc
    25861 gtaccccgct gggggagggg acggcgcggc cgggcgcccg atgtggcggg gcggggtgac
    25921 gggcgaggct gatccgcatg agaaacgtct cgacgaacag caggcccacc ccctcctcct
    25981 cacgcagaag gccgagcgac atgaacactc ccgccaaccc cacgcccgcc ggcacgacgc
    26041 ccgccggcac gacgcccgcc ggcacgacgt ccgccggcac gacgtccgcc ggcgcgacgc
    26101 ccaccggcac gacgtccgcc ggcacgacgt ccgccggcgc gacgcccacc ggcaccaggc
    26161 ctgcccgcac tcgcgtcagg cggctgctcg tcgtgatcgg cgcgtccgtg gccgccctcg
    26221 ccggatggga tctggcggtc ccggtggggg gagcggacct gagcgcgcgg atgggcgccg
    26281 gcacggaccc gcagccggtc gggccggtgg cggtcgtggt ggcgagcctg ctggtcggcc
    26341 tggcgggctg ggcgctgctg gccgtgctgg agcgcttcac gccgcgcgcc gcccgcatct
    26401 ggacgatcgt cgccctgatc gtgctcgccc tgtccctgct cggcccgctc ggcaacgccg
    26461 tcggcctggc cgcgacgctg gtcctgaccg cgatgcacct ggtcgtcggt gccgtgctgg
    26521 tgaccgggct gccccgccga tgatccacct gctcgcctcg gaaggagacc tgacatgacg
    26581 gtgctggcca gagcgatcga cgtgacccgc cgttacggcg gcgtgcgggc gctcgacggc
    26641 gtctcgctcg acatcagggc gggtgagctg gtcgggctgc tcggcccgaa cggcgcgggc
    26701 aagtccaccc tcatcaacct cctcgtcggg ttgcgccggc cgacgtcggg cacggtggag
    26761 ctgttcggcg gctcgccgct ggacccggtc atgcggcgcg gcatcggcgt gacgccgcag
    26821 gagacggggc tgccggagtc gttgcgggtc ggcgagatcg tcgacttcgt ctccgcgcac
    26881 tacccggagc ggctgggcac gggggagctg ctggccaggt tcggcctggg agagctggtc
    26941 aggcggcagg tcggcggctt gtcgggcggg cagcggcggc ggctggcggt ggcgctggcg
    27001 ttcgcgggcc ggccgaagct ggtgttcctc gacgagccca cgaccgggct ggacgtcgag
    27061 gcgaggcggg cgctgtggga cggcatcaag gccttccacg aggacggcgg caccgtcctg
    27121 ctcaccagcc actacctgga ggaggtcgag gcgctggccg agcgggtgct ggtggtcggc
    27181 cagggccggg tgctggccga cgacaccatg cgggcggtgc gcggcctggt gggcacgcgc
    27241 cgcgtctccc tcgtcgccga ccgcctgccc gacctgccgg gcgtgctgag cgccgagcgg
    27301 gtggacggcc ggatcgacct ggtcgtcacc gaccccgacc ggctggtggt ggagctggta
    27361 cgtgccgggg tgccgttctc cggcctggag atcaggccgg ccaccttgga agaggcgttc
    27421 ctcgccctga ccacgaatcc cccgaaggag accgctcatg tctaatctgg tcctcgccca
    27481 cacccgctac ctggtgatcg agcagatcag ggtgccgatc gggatcctgg ccagtgcgtt
    27541 cttcccggcc ctctcgatgg tggcgttcgt ggtgccgttc gcgggccagg acccggtggg
    27601 cgcgaccacg gcgacgggct cgctgatgct gttcggcgcc gtgtccgcgg cgctgacggg
    27661 gctcggcatc gcggtctcgc aggatcgtga gcagccgtgg aacccgtacc tgcgcacgct
    27721 gcccgcgggc ccgctgccgc ggttcgcggg gcggatcctg gcgacgctcg ccgccgtgct
    27781 gatctcggtg gtgccggtgc tggtggtggg ggcgctgctc acggaggcga cgatcacgcc
    27841 ggtccggctg ctggcggggc tgggtgcgct ggtggcgggc gtgctgccgt tcatgctgat
    27901 ggggttgttc gtcgggttcg tgctggcgtc gaaggcggcg atggcggtgt cgcagctgct
    27961 gttcttcccg atggccattc tcggcgggtt gctgctgccg ccggcggtca tgccggagtt
    28021 cgtgcaggcc ctgtcgccgt acgtgccgac caggggtgcg gcggagctgg tgtggtgggc
    28081 gatcgcgggg atcccggcga acggggtgtc gatggcgatg ctggccgtct ggacggtggc
    28141 gatggcggcg gcggccggct gggcgtaccg gcgggacgag ggcaggcgtt tctcctgacc
    28201 cccgaattgg accgatcgtt ctcgatactg ctagggtgca cgacgtggca agaaccaagg
    28261 agttcgaccc cgaggtcgcg ttgcagcggg cgctggagct gttctgggag cgcggctacg
    28321 aggcgacctc aatggccgac ctcgtcgacc ggctcggggt ggcgcgggcg agcatctacg
    28381 cgacgttcgg cggcaagcgc gagctgtacc tgaaggcgct ggagcgctac ctggagcagc
    28441 gcaacgtggt cgagccgctg tcccagccgg ggcccgcgct gcccgccatc cgggccttcc
    28501 tcgactccta cgtggccgag atcctggccg acgagctgcg gcggggctgc atggtggtca
    28561 acacggccgt ggagttcgcc tcgcgcgacg cgaccgtgct ggccaaggtg gcggcgagct
    28621 gggcggagct ggagaccgcg ctggccggca ccctggtcag ggcgcgcgcc cagggggaga
    28681 tcccggcggg caaggatccg tacgcgctgg ccaggttcct gctcgtgctg ctgcaggggc
    28741 tcagggtgct cggccgggcc gacccggacc cgcgccggtt gcgtgacgcg gtcgatcagg
    28801 ccatgacggc tgtccaaatt tgagaatgat tggtcttgaa taagatgact caacggttcg
    28861 caggcaaggt cgcgctcgtc acgggcgcga gcggggtcgt ggggcgggcg gcggcgctgg
    28921 cgtacgcgag agagggcgcg gcggtcctcg tcgccggccg cgacgccgac cggctggccg
    28981 aggtcgtgaa ggcgatcgag gcggacgggg gccgggccgg cgcgttcacc gccgacctga
    29041 cccggtcttc cgatgtcgcc gccatggtgg aggccgccgt cagccgcttc ggcgggctcg
    29101 acgtcgcgct caacacggcc ggcgtcttcg gcatgctcgc gccgctggcc gactacgacg
    29161 aggacgtgtg ggacgacgtc ctcgcgatca acctcaaggg cgtgttcctg tcgatgaagc
    29221 acgagatcgc ccacatgcgc gcccacgggg gcggcgtcat cgtcaacgtc tcctccaacc
    29281 tgggggcgca ctggcggctg gcgggcgcga gcgcgtacgc cgcctcgaag gccgccgtca
    29341 gccacctgac gcgggcggcg gcccgcgacc acatcgccga cggcgtccgc atcaacgccc
    29401 tcagccccgg ccccatcgac agccccatgt cggcgcgtcc cggcgagacc agggagcagc
    29461 gcgacgagcg catgcgcgcc gcgctgccca tcggccgggt ggcggccccc gaggagatcg
    29521 cggccgccgc gctgtggctg tcgtcaccgg agtcgagctt cgtcgtgggc gccgaccacg
    29581 tgatcgacgg cggcgcgacc gcctgacgga tcagctcgtg ggctcgccga accactgccg
    29641 gagccggccg tccagctccc gctggccgtc accgacccag gcgacatatc catccggacg
    29701 cagcaggaca cccggaacgt ccagatcggc ggtgggatcc gcgagcaggt cgacccgatc
    29761 cgcccagccg ccggcactca gacgtccggt acggtccagc agcaggccgc gcccctggtg
    29821 cagcaggtcg tagagacggc cctgcttcac ctcgacgtcc ggcagccggc ggccgagcag
    29881 gtcgtggccc tcgccgaggt cataccggac actgatcgcg gtgatcttct ccgtcaggtg
    29941 gcggttcacg acgtcgaagt ccatcagctc ggtgagcagc cggcgcaccg cccgcgcgcc
    30001 cggctcggcg gagtacagct ccatctgggc gcgggtgttg tccagcacgt ccgccgcgac
    30061 cggatgacgc tcggcatggt acgtgtccag caacgtcccg ggcgcccagc cgcggatctg
    30121 cccggccagc ttccagccga ggttgaacgc gtcctgaacg cccaggttga ggccctgccc
    30181 gccggtcggc ggatggatgt gcgccgcgtc gccggccagc agcacccgcc ccacccggta
    30241 gtgctcggcc agccgcgtgg cgtccccgaa ccgggacatc cagcgcggcg agtgcacccc
    30301 gaaatcggtg ccggcgacgg cccgcaactg ccgccggaag tcgtccagcg tgggcggcac
    30361 cgcccggtcg ccgacctcgg cggcgggcac cacgacgctg tagaccttct cgccgaaggg
    30421 ccgcagccag aaccgctgag gggtgtcacc cagccgcctc agcgcggcgg cgacctcctc
    30481 cggcggcacg cccacctcca tctcgcccat cagcgtgtcg gcccgcgcgg gctcgccggg
    30541 gaacccgacg ccgagcagct tgcgcaccgt gctgcgcccg ccgtcgcacc cgacgaggta
    30601 acgcgaccgc agccgctccc catcggccag ctcgacggtc accccttcgt cgtcctgctc
    30661 gagaccggcc accgcacacc cgtgccggac ctgcgcgccg agcgcgaccg cgtgctcttc
    30721 gagcagccga ttcacgaccg gctgcggaat gcccagcagg tagccgtagg cggaatccag
    30781 accggcgggc gccggcttgt gaataccggc gaacaaccca gcggccggcc gcttccgtcc
    30841 gtgcgcggcg acgcgctcca gcaggccgcg catcgcgagc agttcgagac tgcgaacgtg
    30901 caggccgacg atccgcacga acgacccggg ctcggtgtcc ttctccagga cgagaacccg
    30961 gacgtcgtgc agccgcagct cggcggccag catcgcaccg gtcggcccgc agccggcgat
    31021 gatcacgtcg aacgagagag gcgcgcggtc ggctttcgaa gaaaccatgg gtgttgcctt
    31081 tcggaagtgc cttgtcttgg aggcgctccc ggcgacacct acgtcaatcg cccgaccgcg
    31141 acggcaaggg ggagcaccca tcgatacaca gtcatgggtc tcacctcctc gggcggagtc
    31201 acggtcaccg gcaagctaca agcccgcact cgatcccgtc caacc
//
