LOCUS       NZ_CP017717            22553 bp    DNA     circular CON 03-MAR-2024
DEFINITION  [Actinomadura] parvosata subsp. kistnae strain ATCC 55076
            chromosome, complete genome.
ACCESSION   NZ_CP017717
VERSION     NZ_CP017717.1
KEYWORDS    RefSeq.
SOURCE      [Actinomadura] parvosata subsp. kistnae
  ORGANISM  [Actinomadura] parvosata subsp. kistnae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 13047416)
  AUTHORS   Nazari,B., Forneris,C.C., Gibson,M.I., Moon,K., Schramma,K.R. and
            Setedsayamdost,M.R.
  TITLE     Nonomuraea sp. ATCC 55076 harbors the largest actinomycete
            chromosome to date and the kistamicin biosynthetic gene cluster
  JOURNAL   Medchemcomm (2017) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13047416)
  AUTHORS   Nazari,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) Chemistry, Princeton University, 20
            Washington Road, Princeton, NJ 08544, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUN-2015
            Assembly Method                   :: Celera Assembler v. Jun 2015
            Assembly Name                     :: SmrtPipe 1.87.139483
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 13:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 12,000
            CDSs (total)                      :: 11,919
            Genes (coding)                    :: 11,783
            CDSs (with protein)               :: 11,783
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 36 of 136
            Pseudo Genes (incomplete)         :: 98 of 136
            Pseudo Genes (internal stop)      :: 10 of 136
            Pseudo Genes (multiple problems)  :: 6 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:57:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3504848
            Orig. end                         :: 3527401
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017717.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22553
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="15"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22553
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22553
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12553](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12553
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(2041..2057)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.1"
                     /tool="antismash"
     gene            2951..3376
                     /locus_tag="BKM31_RS59730"
     CDS             2951..3376
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS59730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_155127306.1"
                     /transl_table=11
                     /translation="MNVDEERTDLQHYLDGHRQRIEHLQARIDRAVHELRLHEMIVKLI
                     QNPRLPQAVRGLAEMSSTASRTSIDTRDFLARDGVSVPSDFDISMQGEGDDFSVVITRR
                     DQWYPAELSWSPRDGFQGRILNNAWREAKDAIPTEEA"
     gene            3381..3773
                     /locus_tag="BKM31_RS59735"
     CDS             3381..3773
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS59735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_155127309.1"
                     /transl_table=11
                     /translation="MGAISELHFVNNFSTNALTLTNLEPDPDYEKTCSPGRSTFVNYQW
                     IPWCSKGSDFPAHHIRITLGGVIFFVWQHTDTDGNWVRLSTTGFTSSDIPPFTPAPKFP
                     GIAFEGGDRNIDVASDGTMRLIDAAP"
     misc_feature    complement(3408..3423)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.83"
                     /tool="antismash"
     gene            complement(3869..4351)
                     /locus_tag="BKM31_RS16055"
                     /old_locus_tag="BKM31_15895"
     CDS             complement(3869..4351)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15895"
                     /product="hypothetical protein"
                     /protein_id="WP_080038922.1"
                     /transl_table=11
                     /translation="MVQHWSISQVREVVNEHEDAWLIHYDPIDGDLRDAFVAYVPKEAL
                     EWRAAEFGLTTVDEALEVQLYLPLLAPGQAAGTLDMLNPSAMPVEQAHAHVTELLATCK
                     KQHGVIQQPASNVRTGRADPLTVIRERTRIDVVRTTAMRLEIDRALLAREGQQEDN"
     gene            complement(4492..7500)
                     /locus_tag="BKM31_RS16060"
                     /old_locus_tag="BKM31_15900"
     CDS             complement(4492..7500)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15900"
                     /product="hypothetical protein"
                     /protein_id="WP_080038923.1"
                     /transl_table=11
                     /translation="MLELRLVVHTPNEARLGVLPHPQSVEVACPLDDVPALTLSYSANA
                     VNADLLGGPVEVAVEWSIDGQTWMEGPDARFLRIKQRGDGTDRAGMKRFELPGYVWQLR
                     KLLLFPGAAPLVEGKRAFLSATPGAILATFLQEGQARGAAAGFSWDFTPTHDSAGQPWA
                     KILTIYYQPGIDALTTLINLAEQGTLDFRMAGRTLQVYNADTELGRDLASGSGPVDLRF
                     GRDVVAAPDIGTYEDAATSALVVGDDGFRMSFTNGAAEAPWGRWETYIGQGGVSDPGTA
                     QLLAEAVLLRAGHERVQRTRQITPHTARWLPWRDYRPGDRILAPGEAGAMESLRVRQMT
                     VTRDEKGVLGGNLVLNDRLLERDLRLARRTAGIVGGSTAEGGSGARPAPESPTPRTPAA
                     PAGLIVNPLAYIDEHGLPRGQVAAAWGAVITDVNAVALTVGGYELFMRINEVGAPWFLV
                     TATEAADTNATYSPLVVGQQYQFKVRAVNLGKKGPFSSSVAVTIPDDVDAPPVPTAPAL
                     ESRLGVVHVAWDGLGVGGVPMPADFHRVLVWMQDPLAPGWQEIGALDAAGSLVVPGLPY
                     DLDREFSFTSIDRSGNSSARSATGMIAAVRLVEGDAADESITTGAIVANAITAAKIAAG
                     QILAGHIAANQITAAKLEAILTLATRIVAGVATGARVELNADGLQAYNNSSVQTVSVSS
                     ASGAVSIVGQLATGVSGRRIIVNPAGAADPEIRFMPGTGTNSARIWTDTDAAIRLNSGN
                     SPDGTRRSEVIQRGDEWRMHMVQTADGLAGGGYMFAQPDELEVGYNDIGGNLNRFRFSA
                     ASTGFIGKWSYSTSGAGLIMRAVSLSGGSAYNVTWGGPIMQTTPRAVFTPDNPIPDRLH
                     FYLRNPSTSGFELRSNESSLGTPTVFAVLLDIWAWRGLKLGVVASHANSDRKAPTDLSD
                     FILDTDFRIDAECTIRRRCTRKQRLDLDGRSQSERLFTAPLVAASNLTQDLIDQCLPDR
                     LRCSNGTELFGYP"
     misc_feature    complement(7483..7485)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7672..8460
                     /locus_tag="BKM31_RS16065"
                     /old_locus_tag="BKM31_15905"
     CDS             7672..8460
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15905"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_080038924.1"
                     /transl_table=11
                     /translation="MPRRSSRWSRAPSPLRQARLARNWTLEDVVEEIDLRTPGGQSGVT
                     PSMVSGWELARHTTSIGHRKTLCEIYGRSPRQLFAFQDEQLPEQAGLGLLTGFEELQQA
                     MLATVRGAQRCLVVTGSRSRDAGYLKATEAVLAERPGLVYYRVLFGPPHHQVLKDHLLR
                     LLRLRDPRDRGLGVKTLHLGLVEDTVAMPERWFCASEQTAVVPIPSLTSHEAFDSGVML
                     GAAPAARLLDHGRQAYAAARRVETTTEVAALDVLVPERSG"
     gene            8479..9702
                     /locus_tag="BKM31_RS16070"
                     /old_locus_tag="BKM31_15910"
     CDS             8479..9702
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017536288.1"
                     /locus_tag="BKM31_RS16070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_15910"
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_230466182.1"
                     /transl_table=11
                     /translation="MDDTVGDAGGGPVDPVRAAHQDHDSVVELTRELVRVPSRGGIDAY
                     EPVLDHMAGWLAAHGLPCAHLAGPGGGVVALVCEVAGDAPGPCYVLDACLDTAPFGDDA
                     AWAYPPTSGRIHDGWLHGRGSSDSKAGAAIFAHIAARLHRAARTWRGSVVLLFDIDEHT
                     GGFGGAKAFFEREDAPHRVDGVMIGYPGLDHVVTGGRGVLRARVQVHGIAAHSGGSRAA
                     PSAIHKAAEATSRLHRAPLPGPGGPGFPLPPKLTVTAIHGGEGYSTIPDLCILHVDIRL
                     TPAFEAEQALALLRSTLAGLDADWPDTPPTNLTVTTRWPAFALPEHEPLRAALLAAAQA
                     TGLHPQAKVAGPSNIGNYLAGLNIPAIAGFGVDYRGLHATDEQIRLDSIPPVQATYHRA
                     LLSLLPAC"
     gene            9862..9996
                     /locus_tag="BKM31_RS59740"
     CDS             9862..9996
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="BKM31_RS59740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_186404076.1"
                     /transl_table=11
                     /translation="MDHPTPAGYEAPHLSPVGSFATSTLGSYSKDTSDDSDAGQYYPS"
     CDS_motif       9862..9936
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MDHPTPAGYEAPHLSPVGSFATSTL"
                     /locus_tag="BKM31_RS59740_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9937..9996
                     /prepeptide="core"
                     /locus_tag="BKM31_RS59740_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-1.90"
                     /molecular_weight="2025.0"
                     /monoisotopic_mass="2023.8"
                     /core_sequence="GSYSKDTSDDSDAGQYYPS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MDHPTPAGYEAPHLSPVGSFATSTL"
                     /leader_location="[9861:9936](+)"
     gene            10001..11917
                     /locus_tag="BKM31_RS16075"
                     /old_locus_tag="BKM31_15915"
     CDS             10001..11917
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="BKM31_RS16075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_15915"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_080038926.1"
                     /sec_met_domain="Asn_synthase (E-value: 4e-24, bitscore:
                     85.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAAHSAWFVALPDAAIARAASDTLLAARGGVLARHASGRPWII
                     GYGYHTPAPPQRYGDELRTAAAGRLRIAIAGFCPAPDRELRRAAAQAGRGRVEDLLRLP
                     GSFHLITCAEGQVSLYGDVAGLRRLFHSRLDDGLPVAGDRAAALAALTGGALDERWLGA
                     RLLNPEMPADLLWSRLSPYRGVVPVPPGHRLRLDHDGVSAACYWRPPAAVLTLTEGAEL
                     LRTALSRAVEAAVSQAGRASVQLSGGWDSAALAALACRARPKGGTLLLTVASATADNPD
                     VRWARHTANRLRPAEHQVLEACSYPLLFDGLAEPIVTDEPASFMVSSARIRHLTGVLTR
                     YGSAAHLNGQGGDEVLLAPLAHLFDLWRRPGLAWHHLRGYAALSGVGTLPLLAALLRAR
                     PSWRGPRRDAGGASLRWAPASARPTFRPTLVTGSEAVPLLPPWATAAATEQAATLLDML
                     DPPEGDTVTHATVTRIRACARRAAAYRDALAQHDVPAHFPYFDQAVIDACLATRPEVRT
                     TPYQPKPLLAAALAPIAPGLLVRRDKGHHNHDLHAGLAAHAPHLLELFGDDCALARAGV
                     IDAALLRRALTGTGPSSVAGGLPLAFLTETLAMELWLRHRTGGSDHVLEPGPGRAPDRR
                     AAV"
     gene            11865..12116
                     /locus_tag="BKM31_RS16080"
                     /old_locus_tag="BKM31_15920"
     CDS             11865..12116
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="BKM31_RS16080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_15920"
                     /product="PqqD family peptide modification chaperone"
                     /protein_id="WP_080038927.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.3e-14,
                     bitscore: 51.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.8e-10, bitscore: 40.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWNLAPAVRRTGALLFDGGRGGYFALNPTATQTLEVLLTGGTCE
                     QAAQELAAAYAVGTERALADVAALVADLTNRQLLRQAG"
     aSDomain        11898..12104
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BKM31_RS16080_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.00E-16"
                     /identifier="RREFam002.1"
                     /label="BKM31_RS16080"
                     /locus_tag="BKM31_RS16080"
                     /protein_end="80"
                     /protein_start="11"
                     /score="51.7"
                     /tool="antismash"
                     /translation="TGALLFDGGRGGYFALNPTATQTLEVLLTGGTCEQAAQELAAAYA
                     VGTERALADVAALVADLTNRQLLR"
     gene            12113..12553
                     /locus_tag="BKM31_RS16085"
                     /old_locus_tag="BKM31_15925"
     CDS             12113..12553
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="BKM31_RS16085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_15925"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_080038928.1"
                     /sec_met_domain="PF13471 (E-value: 1.1e-20, bitscore: 73.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTLVALPEPIALTGREQLRGRTALLATRLLLARHRSHPDRLAAH
                     LAVRARGFSRATAQQARHAQTVITTLSPRCGSGRGCLPRSIATALACRALYLTWPTWRV
                     GMRYPPLMSHAWVQADGQPIGDDPEVIAAYTPTYTVGPEGAP"
     gene            12550..13677
                     /locus_tag="BKM31_RS16090"
                     /old_locus_tag="BKM31_15930"
     CDS             12550..13677
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013315.4"
                     /locus_tag="BKM31_RS16090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_15930"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_080038929.1"
                     /sec_met_domain="PCMT (E-value: 8.5e-35, bitscore: 119.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAPATESTAGRMARLAEQLRELGAIRTDAVHHAFATVPRHLFI
                     TGFYTGGDAYTRLGDPPGDDLLDQIYSDVALMTHRPSDAAGRPSSASMPRVVARMLEAL
                     DLRPGLRVLEIGAGTGYNAALIAAITGADVVSVDVSEVIVAEAQAALQRANASNTAAYV
                     ADGYLGHPDRGPYDRIIVTCGITGISPRWLEQLAPGGLILAPIAHAGFHPTLAITLDGA
                     GRPIGRGILSSDFMAAGGPLYGRPADQTSPPGEVPADGGLTVWPGTVPALADDRYFDLW
                     FALGAADPRTIRAYTPGLDAALGMVCLHEPGRGTAWVQRDGAIRFTGHQDLAHQLTALT
                     QQWDSADRPRISDWTAGFVLSEAADPLWHPAAWAR"
     gene            complement(13855..13986)
                     /locus_tag="BKM31_RS64270"
     CDS             complement(13855..13986)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS64270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268966963.1"
                     /transl_table=11
                     /translation="MPARFRSTHVVETARMVLQAVPVEQQARPAVADLRSMLAIEAG"
     misc_feature    complement(14174..14185)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.01"
                     /tool="antismash"
     gene            14216..14455
                     /locus_tag="BKM31_RS62485"
                     /old_locus_tag="BKM31_15940"
     CDS             14216..14455
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS62485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15940"
                     /product="hypothetical protein"
                     /protein_id="WP_230466183.1"
                     /transl_table=11
                     /translation="MRPLLSKSHQSTEHVEGFLMATHHGQGLGLGSDELEHRFSASEVA
                     GLGHTPQDGFWRLLPVQAMTGLLRANQQPQRQVS"
     gene            14564..15148
                     /locus_tag="BKM31_RS62490"
                     /old_locus_tag="BKM31_15945"
     CDS             14564..15148
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS62490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15945"
                     /product="hypothetical protein"
                     /protein_id="WP_230466184.1"
                     /transl_table=11
                     /translation="MQLAPFLDARALHLPRQGVQVDGDVAGDLEGRTGPKRVEMPLVDD
                     GPFLGAAASAYHGVEPSPDDFSVKGRSQSSTGGYLQQATAFRGVLPVIDVIEAQSTHRA
                     HLVGRGAKLRMLSENLISLVNSKKLAIRTQGRIERDGDSPCRVSTAFLQIVNGGFAHRC
                     SLREGTKRKIRILPQTVEHLSEGLCHQCPPT"
     gene            15714..15932
                     /locus_tag="BKM31_RS16100"
                     /old_locus_tag="BKM31_15950"
     CDS             15714..15932
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15950"
                     /product="hypothetical protein"
                     /protein_id="WP_080038931.1"
                     /transl_table=11
                     /translation="MKALRDWRNLDGHSFDEELFAPIRPGEENGLEFVPIAGAEGVAAL
                     RRPSQPHAVLLVTALELDTLLHLLRCR"
     gene            16197..16496
                     /locus_tag="BKM31_RS16105"
                     /old_locus_tag="BKM31_15955"
     CDS             16197..16496
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15955"
                     /product="hypothetical protein"
                     /protein_id="WP_080038932.1"
                     /transl_table=11
                     /translation="MVERVNDHVEMRVDERVLTASLDGWAQFLRAVQDGKPTDGSVRLR
                     TDVAHAATLWNVEADGDPLNLNAEEWATVREHIERGDFDLEKLPRQAQEPDTVA"
     gene            16960..17145
                     /locus_tag="BKM31_RS16110"
                     /old_locus_tag="BKM31_15960"
     CDS             16960..17145
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15960"
                     /product="hypothetical protein"
                     /protein_id="WP_080038933.1"
                     /transl_table=11
                     /translation="MHDVGAILGDSDPTVGHGNGPAYRCDRIHTTLPRTSMVSHRVIHE
                     EHPTSDHRPVVAEFEV"
     misc_feature    complement(17004..17014)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(17158..17946)
                     /locus_tag="BKM31_RS16115"
                     /old_locus_tag="BKM31_15965"
     CDS             complement(17158..17946)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15965"
                     /product="hypothetical protein"
                     /protein_id="WP_155127315.1"
                     /transl_table=11
                     /translation="MRSVSVKVPGVAGELPVHGLDLETTTLPLVIGVTGRTPSGGAGGF
                     EQLERNLEAISAMLGVRHRLMDLTYTAGSIVRVAQVTVEAVSEPEINTSAARARLTAVV
                     KIPAVYWRDPIEAVWTGSANAASQPITPLAGSTGRIVDALVRVTGPAVNLSVTDVVTDV
                     ATGATVGRPSGLLAGERLLIDCGQMRARLVTTDTWDFTGGADVTGQITAAGPGSASRWL
                     HLTPAIAVGDPHSRTVLITAAATSTTAASGLEVRARRSFL"
     gene            18125..18580
                     /locus_tag="BKM31_RS16120"
                     /old_locus_tag="BKM31_15970"
     CDS             18125..18580
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15970"
                     /product="hypothetical protein"
                     /protein_id="WP_080038935.1"
                     /transl_table=11
                     /translation="MTDISYFDAWQLWLDGRSTLGNDLLGMQMIWWGRGGKILSFLSGV
                     TIVVDLVGPEKFSRYGHWIQRLLNVQVWHFPVVPFVVGGVVGVLTPSRLDTESIVANLI
                     GWAIGVSLVLLLLRFSFLLINPQMALIIRWMSLGLFVVGFHFDLLAS"
     gene            complement(18607..19437)
                     /locus_tag="BKM31_RS16125"
                     /old_locus_tag="BKM31_15975"
     CDS             complement(18607..19437)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15975"
                     /product="hypothetical protein"
                     /protein_id="WP_155127318.1"
                     /transl_table=11
                     /translation="MRIMLREPAPPVRRRVEQPTLLPLHPQQPHGRLRVGQLPMVLGRL
                     GPWAAAVARDLDEGDRAQHDATMQRAYDLQAEFVELPHAVRIHLPRGLYQQPLITLVQS
                     AALLLRGDLVGALATAGRAILDFLVVIDNLGWQLLQGLWNGIQAAAGWFRDVIWGFFRN
                     ILPDWVRAAMGISSPSTLFAEIGQFTMLGMAEGMQTSARTVLATVTRISGDIERSFRPR
                     LAVDLGSAGHIVTGAPNRAGGSVTIQVTAINPVAEPASETVNRGLAYAGMLGVL"
     gene            complement(19536..20630)
                     /locus_tag="BKM31_RS16130"
                     /old_locus_tag="BKM31_15980"
     CDS             complement(19536..20630)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="BKM31_RS16130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_15980"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_080038937.1"
                     /transl_table=11
                     /translation="MQAEITLSSSVKRSARVLQLQGLFDVPISEKLAGSWSVNLPIEER
                     TWNVGLLVGPSGAGKSTIARKLWPDALVGSQCWSDRALVDDFPKNMSIKEVVGLLGTVG
                     LNSPPAWLRSYATLSNGEAFRAGLARALAEHEGLVVIDEFTSVVDRQVARIASHAAQKA
                     VRRRKRQLVAVTCHYDVEEWLQPDWTYDVAAAEFTWRSVQPRPPLQFAIHQADRSLWSV
                     FSRHHYLTADLHPAAQCFVGYVDGELAAFTSYRHFQHPRTRNLKMAHRTVVLPDYQGLS
                     LGGRMTEWMGQYLYERGYRMRAVSSHPALNAYRARSPRWRVQRQDRKLGTTSKHAWMHE
                     QSLDPRRLGVLSFEYVAPSPVKAS"
     gene            20711..21655
                     /locus_tag="BKM31_RS16135"
                     /old_locus_tag="BKM31_15985"
     CDS             20711..21655
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS16135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_15985"
                     /product="hypothetical protein"
                     /protein_id="WP_155127321.1"
                     /transl_table=11
                     /translation="MTTLNHDQLLASARDFAHRALRAYVEDDQRVILINAAFSLEHLSK
                     AYLYAQHPALLMEVRNGQFDSLLHLTGLGGKARKLKAPRTISAKEALARVEQLMTLRTP
                     RAALDELIDVRDGVVHVGYLSQTSTREILTVFLRFSNELYEEQGVDESARWGDHSTLVT
                     SLITQALSEIEHEVQRKIAAAKRRIGELMSKIPESEHVAVGDARQAMTPFQRYLDQEAS
                     ASGSRDHRITIRCPACNHPDASCIGHIEWDFDMPAEIGSMDRIEEVAGQEEYFLPRALL
                     CGSCDLRLDSEDELQAVGIPRRVVFGGRGLQLQ"
     misc_feature    complement(21728..21738)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            21733..22098
                     /locus_tag="BKM31_RS16140"
     CDS             21733..22098
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015513.4"
                     /locus_tag="BKM31_RS16140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_080038939.1"
                     /transl_table=11
                     /translation="MAGLERITQPTLDVLEVLVTAHDRNERVHGWAIMKTTKRAGPTVY
                     KVLDRLEDAHWVVGEWEELGPDQPGPRRRFYQLTGEGAPAARALLIKRRPSALQPRPAT
                     DFASLSKLLGLAFGGTR"
     misc_feature    22075..22077
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 cgtggcgccg taggagaagg acgcgaactg gccggacccg aacgtcaccg atccggcgaa
       61 gacgcccgcg gtgttgccct gctgggtgta gtcccaccac ttcccgacgt gcctggtcct
      121 gccgctgttg tcgaaccaga agtactgctc cctcgcggcg tccttgaagt agccgtagcg
      181 ggcgtagcct tcggcgatct ccatcagccc cccgttgggg gtggacagcg aagagttcaa
      241 gacctgcatc gacaagaacc cagcggccac caccgtggac gacgccgcgg tctgcccctg
      301 attcgtcccc gaggtgatct cgaacgtcgc ctctccagcg aaccaatcgt cgcgggtcgt
      361 cagcctcgtg tagttcgtac cgctgcccgg gtagaaccgc atctcgggga acgtcgtacc
      421 gggcggctgc aagtcgatcc gccggcctgt cgccgcagtc ctgatgttcg agccggtgat
      481 ggtcttaccg tcgatcgctg tggccgccag cttgttcgct gtgaccgccc cggcagagat
      541 ggatcccgcc gtcaccgcgt tggccgcgat gtgcccggcc tggatagccc ctgctgcgat
      601 cttgtcagcc tcgacggcgt tggcctggat gtgccccgcc tgaatggcgc cggattggat
      661 gagcgccgca gtgatagacc cgacgacgat cttcgcttcc gccgggatcg accccgtgat
      721 gatgtgctcc gccccgtcga tgacctcccc gatcaggtcg gtgtccacca gcggagtgac
      781 cgccacgatg acatgcgccg acggcgcgga ctcgtttccc gaccggtctg cggcgctcag
      841 ccagatctcc cgatccgcct cgtacggctg ccccgggatc acctccgttc cggcgctggt
      901 caggtagccg acacgggttc cggtgtcggc cgggtcaagc gggtcacgca tccagacgtg
      961 gacccggtcg aggtcgagcg gcatcgcctc gcccgcgctg cccaggccgt cccacgtcac
     1021 gtggatcact ccgagccggg cggcgacgag cggcgttgac ggggtcggcg gcggcgtcgc
     1081 atcgtccggg acgagcacca cgaactggct actgaacacg cccttggtgc cgtcgttcgt
     1141 cgctcgcacc ttgaagctgt actcccagcc gacgaccaac ggagagatcg tcgccgtgcg
     1201 atcggccgag tcggtctgcg cgaccagcac ccacgggacg ttcgcctcgt tgcggcgggc
     1261 gtacacctca tacccatcga cgctcaggtc cccgccgttc acatccgcgg tgaccgcgcc
     1321 ccacccgagt gtggcctgcc cgtgcgcgta gccatgctcg tccagatatg cggccggctc
     1381 gacaagcagg ccacccggcg cggccgggac gcggccgtcg gtgtccggcg ccggcgttcc
     1441 cccgccgcct cccgagctga tgccgccgtc caggatgccc agactgcgcc gcgccagcct
     1501 gaggtcccgc tccagaaacc gatcgttcaa gacgagattg ccgccgatcg caccgtccgc
     1561 gtcgcacgac agcgtgatct gccggaccct caggccctgc atcacgccct ggtcgccggg
     1621 cgcgagcacg gtgtcgcccg gccggtagtc gcgcaacgcc agccagcggg cagcgtacgg
     1681 cgtgacctgc cgggtgtgct gcacccgctc cctcgatgcc cggtccagtg cgtactgggc
     1741 cagcacgcgg gcggtcccct cgtccgacac tccggactgc gactggtacg tctcccagcg
     1801 gccccacggg gcgagggcgg ccgggttggt cacctcgacc tgcagcccgt tctcgccgac
     1861 gatcaggatg gcggtggaga cgtcctccaa ggtcgcatcg tccggcgcgt cggtgacgtc
     1921 gcgtcccatc cgcaggtcca ccggagcggg accggtcgcg aagtcccggg ccagcgtcgt
     1981 gccctcgttg aaggcgcgca gcacccggcc ctgcatggtc cagtcgagca cgccctgctc
     2041 tgccaaattg atcatcagag tgagcaggtc cgcgcctggg tccagcccga tcgtcagcag
     2101 cttgtcccac ggctgccccg cgctgtcgtg cgtcggtgtg aagtccaccg ccaggcccgg
     2161 gagcgtcccc cgcgcctggc cctcatcgac taccgtccgc aggatcgcgc ccggagtggc
     2221 cgcgttgaac ggccgcttcc cgtccaccat cccggcaccc gggtacagca ccagcttacg
     2281 tagctgccac gaccagcccg gcgcgtcgaa cgacaacggg cccgcgtgat cgctcgcgtc
     2341 cgaaccgcgc ttgatccgca ggaaccggcc cccctgcggc tccgtccacg ccccgcccgc
     2401 agaccactcg atcgcgatct cacacggctg cgccagccac tgcgcgccgg ccgcgtgcgt
     2461 cgagtacgtc agccgcagcg ccggaatatc gttcagcggc agcgcggcct cgaacccgag
     2521 atgctgcccg agcaggccaa gacgcggccc gttcggctga taagcaatca agcgcagccc
     2581 gtaacgcatc ggctcgcttg gaatgatgat ctgcacgacc tacccctttg cgatgccgtg
     2641 cctcggcatg gcctccaact gatcaagtcc gcgacggaca ttcacgtcca tgaacctgag
     2701 cccttgggac gacaaggctt tcgctccagc gaaagttgta gattatgtgt cctatatcgg
     2761 ccagaggtgc acgtcagcac aggtcaggca tgatggcgtt gcctgagtaa ggatgtcttc
     2821 tgcacctgcg cttgctcgtt ggcatgcagc gcgctacttt gaacgcatcc agctaactaa
     2881 gcggctagat caagcctgac atgatctagc gcctcaatgg atcgtcgatt cctgagaagg
     2941 tgcattcgca atgaatgtcg acgaggagcg tacagatctg cagcattatc tcgatggcca
     3001 ccggcaacgg atcgagcacc tgcaggcaag aatcgatcgg gcagtccacg agttgcgtct
     3061 gcacgaaatg atcgtgaaac tcatccaaaa tccgcgacta ccccaagcgg tgcgcggact
     3121 cgcggagatg tcaagcactg cctcgcgtac atccatagac actcgagact tcctcgccag
     3181 agacggcgtg agcgtccctt cagatttcga cataagcatg caaggtgagg gtgacgattt
     3241 ctccgtagtc atcacccgcc gtgaccaatg gtacccagcc gaactgtcgt ggagccccag
     3301 agacggtttc cagggacgga tcctgaataa cgcatggcgg gaggccaaag acgctatccc
     3361 gaccgaggag gcatgatgct atgggagcga tcagcgaact ccacttcgtg aacaacttct
     3421 caactaacgc cctcaccctt accaacctcg agcccgatcc agattacgag aagacctgct
     3481 ctccaggacg ctcaactttc gtcaactatc aatggatccc gtggtgcagc aagggatccg
     3541 actttcccgc ccaccatatc aggattacgc tgggcggcgt gatcttcttc gtgtggcagc
     3601 acacagatac agacggcaac tgggtacgcc tctcgacgac tggctttact tcgagcgata
     3661 tccccccatt caccccggcg ccgaagttcc ctgggatcgc gttcgaaggc ggcgatagga
     3721 atatagatgt cgcatccgat ggcacgatga ggctgatcga tgccgcaccc tgacatctgc
     3781 gcttttctga agcagcacag ctcggcgatg cgacttcaaa ggccggggag tcgcttctcg
     3841 tcacccatgg cctagctgtc acaggtcctc aattatcctc ttgctgtccc tctctcgcga
     3901 gaagggctcg gtcaatctcc agccgcatcg cggtggtacg cacgacgtcg atccgtgttc
     3961 gctcccttat aaccgtcagc gggtcggccc gccccgtccg cacgttgctt gctggctgct
     4021 ggatcacgcc gtgctgtttc ttgcatgtgg ccagcagttc ggtgacgtgt gcgtgggcct
     4081 gctcgaccgg catcgcggac gggttgagca tgtcgagagt cccggccgcc tgaccgggcg
     4141 cgagcagcgg caggtacagc tgtacctcca gcgcctcatc gaccgtggtc aggccgaact
     4201 ccgccgctcg ccactccaac gcctccttcg gcacgtacgc gacgaacgcg tcacgcaggt
     4261 caccgtcgat cgggtcgtag tggatcagcc aggcgtcctc gtgctcgttg acgacctcgc
     4321 gaacctgtga aatagaccaa tgttgaacca ttagctaagt gcgcctaccc ctccgaagag
     4381 gatctctatt tctcgatcat gcgaagcgcc attgacgacg ctgaaaattg agcagatact
     4441 cgccacacgc ctagaaaatc gggatctgtt atggacgtca gcgtcatacg cttaagggta
     4501 gccgaaaagc tcagttccgt tgctacacct gagtcgatcg ggcaagcact gatcaatgag
     4561 atcttgcgtc aaattgctag ccgcgacaag tggagcggtg aagagtctct cactctgcga
     4621 gcgaccatcg agatcaagcc tctgcttacg cgtacagcgt cggcggatgg tgcattctgc
     4681 gtcgatgcgg aagtctgtat cgaggatgaa gtcagacagg tcagtaggtg ccttcctgtc
     4741 actatttgca tgtgatgcga caacccccag ttttaggccc cgccacgccc agatatccaa
     4801 caggactgcg aagaccgttg gcgtcccaag agatgactcg ttggaccgta gttcgaatcc
     4861 ggatgtgctt gggtttcgca ggtaaaagtg cagtctgtct ggaatagggt tgtctggagt
     4921 aaacaccgcg cgcggggtgg tctgcatgat cggaccgccc cacgtcacgt tgtaggccga
     4981 cccgcctgac agcgacaccg cccgcatgat caaacccgcg ccggatgtgc tgtacgacca
     5041 cttgccgatg aaccccgtgc ttgcggcgga gaagcggaac cggttgaggt tgccgccgat
     5101 gtcgttgtag ccgacctcga gctcatcagg ctgcgcgaac atgtaaccgc cgccggcgag
     5161 cccgtcggcg gtctgcacca tgtgcatgcg ccactcgtcg ccgcgctgga tcacctccga
     5221 gcggcgggtg ccgtcagggc tgttgccgga gttcagccgg atcgcggcgt cggtgtcggt
     5281 ccagatgcgg gccgagttcg tgccggtccc cggcatgaac ctgatctccg ggtcagctgc
     5341 cccggccgga ttgacgatga tgcggcggcc ggacacgccg gtcgcgagct ggccgacgat
     5401 gctgacggct ccggacgccg acgagaccga cacggtctgc acgctggagt tgttgtacgc
     5461 ctgcagcccg tcagcgttga gctcgactct ggccccggtg gcgactcccg cgacgatgcg
     5521 ggtggccagg gtgaggatgg cctccagctt tgccgccgtg atctggttgg cggcgatgtg
     5581 cccagcgagg atctgcccgg ccgcgatctt cgccgcggtg atcgcgttgg ccacgatggc
     5641 gccggtggtg atcgactcgt cggccgcgtc gccctcgacg agccgcaccg cggcgatcat
     5701 cccggtcgcc gaccgggccg agctgttccc ggaccggtcg atgctcgtga acgagaactc
     5761 ccggtccagg tcgtacggaa ggccgggaac gacgagcgac ccggccgcgt cgagcgcccc
     5821 gatctcctgc cagcccggag cgagcgggtc ctgcatccag acgagcaccc ggtggaagtc
     5881 ggccggcatc ggcacaccac cgaccccaag accatcccat gccacgtgga cgacaccaag
     5941 acgagactcc agcgccgggg cagtcggcac gggcggggca tccacgtcgt ccgggatcgt
     6001 caccgcgacc gagctggaga acgggccctt cttgcccaag ttcacggcgc ggaccttgaa
     6061 ctggtactgc tggccgacca ccagcggcga gtaggtggcg ttggtatcgg cggcctccgt
     6121 cgcggtcacc aggaaccacg gcgccccgac ctcgttgatc cgcatgaaca gctcgtatcc
     6181 acccacggtg agcgcgacgg cgttgacgtc ggtgatgacc gcgccccacg cggcggccac
     6241 ctgcccgcgc ggcaggccgt gctcgtcgat gtaagccagc gggttcacga tcagcccggc
     6301 cggggccgcg ggggtgcgcg gcgtcggcga ctccggcgcg ggccgcgcac ccgacccgcc
     6361 ctcggccgta ctcccgccga cgatgccggc cgtgcggcga gccagccgca ggtccctttc
     6421 cagcagacga tcgttgagca ccaggttgcc gccgaggaca cccttctcgt cccgggtgac
     6481 ggtcatctgc cggacccgca ggctctccat ggccccagcc tcgcccggcg cgaggatccg
     6541 atcgccgggc cggtaatccc gccacggcag ccaccgcgcg gtgtgcggag tgatctgccg
     6601 cgtccgctgc acccgctcgt gcccagcccg caacagcacc gcttcggcca ggagctgcgc
     6661 cgtacccgga tcgctcacgc cgccctgacc gatataggtt tcccaccggc cccaaggagc
     6721 ttcggcggcc ccgttcgtga acgacatgcg gaacccgtca tcgccaacca cgagcgccga
     6781 cgtggccgca tcttcgtagg tgccgatatc gggagcggcg accacgtcac ggccgaaccg
     6841 caagtcaacc ggcccgctac cgctggccag gtcccgcccc agctcggtgt cggcgttgta
     6901 cacctgcaac gtccgcccgg ccatgcggaa atcgagcgtg ccctgttcgg ccaggttgat
     6961 cagcgtcgtc agcgcgtcga tgcccggctg gtagtagatc gtcaagatct tcgcccacgg
     7021 ctgcccagcg ctgtcgtggg tcggggtgaa gtcccacgag aagccagccg ccgcgccgcg
     7081 tgcctgcccc tcttgcagga acgtggccag gatcgccccc ggcgtcgcgc tgaggaacgc
     7141 cctcttccct tccaccagcg gagccgcccc agggaacaac agcagcttgc ggagctgcca
     7201 cacgtagccg ggcagctcga accgcttcat cccggcccgg tccgtcccgt caccgcgctg
     7261 cttgatccgc aggaaccgcg cgtctggccc ttccatccag gtctgcccgt cgatgctcca
     7321 ttcgacggcg acctcgaccg gcccgcccag caggtccgcg ttcaccgcgt tcgcgctgta
     7381 ggacagcgtc agcgcgggca cgtcatccag cgggcacgca acctccacgc tctgcgggtg
     7441 cggaagaacc cccagacggg cctcattggg ggtatgaacg actaaccgca gctccagcat
     7501 ggtcgtgtca cctcccctca ttcgggaagc gccgcagaag atcacacgcg tgccgctcgc
     7561 agggtctcgt cgcgaatgac ctgcccgagt cgaaaggacg gggcattatc gggggtgcct
     7621 ggtgccggac ggctggcgcc ctggacccgc cttggcgggg aggaggctgg tatgcctcgt
     7681 cgctcgtcgc gctggagtcg tgcgccctcg ccgctgcgtc aggcgcggct ggcgcgtaac
     7741 tggacgctgg aggacgtagt cgaggagatc gacttgcgga cgccgggcgg ccagtcgggg
     7801 gtgacgccga gcatggtgtc gggctgggag ctggcccggc acacgaccag catcggtcat
     7861 cgcaagacgt tgtgtgagat ctacggacga tcaccgcggc agctgttcgc cttccaggac
     7921 gagcagttgc cggagcaggc cgggctgggc ctgctgactg ggttcgagga gctgcagcag
     7981 gcgatgctgg cgacggtgag aggcgcgcag cggtgcttgg tggtgaccgg atcgcgctcg
     8041 cgcgatgcgg ggtacctgaa ggcgactgag gcggtgctgg ccgagcgacc ggggctggtc
     8101 tattaccggg tgctgttcgg cccgccgcac caccaggtgc tcaaggatca cctgctgcgg
     8161 ctgctgcggt tgcgtgaccc gcgtgatcgt ggcctggggg tcaagacgct gcatctgggg
     8221 ctggtggagg acacggtggc gatgccggag cggtggtttt gcgccagcga gcagacggcc
     8281 gtggtcccga tcccgtcgct gacctcgcac gaagcgttcg actcgggggt gatgctgggg
     8341 gcggcgccgg ccgcccggct gctggatcat ggcaggcagg cctacgccgc cgcgcgccgg
     8401 gtggagacga cgacggaggt cgccgcgttg gatgtgctgg tgccggaacg gagcgggtga
     8461 ggctggatga cagggcgcgt ggatgacacc gtgggggacg ccggtggcgg ccccgtcgat
     8521 ccggtgcggg cggcgcacca ggatcacgac agtgtggtgg agctgacccg ggagctcgtg
     8581 cgtgttccca gccggggtgg catcgacgcc tacgagccgg tgctggacca catggccgga
     8641 tggctggccg ctcacggcct gccgtgcgcg cacctggccg gaccgggcgg aggcgtggtc
     8701 gcgctggtgt gcgaggtggc cggcgacgcc cccggccctt gttacgtgct ggacgcctgc
     8761 ctggacaccg cgccgttcgg cgatgacgcg gcctgggcct acccgcccac ctcgggacga
     8821 attcacgacg gatggctgca tggccggggt tcctcggact ccaaggcggg ggcggcaatc
     8881 ttcgctcata tcgccgcccg gctccaccgg gcggcccgca cctggcgggg cagcgtggtg
     8941 ctgctgttcg acatcgatga gcacaccggc ggcttcggcg gcgcgaaagc cttcttcgag
     9001 cgagaagacg cgccgcaccg cgtcgatggg gtgatgatcg gctaccccgg cctggaccac
     9061 gtcgtgaccg gtggccgcgg cgtgctgcgc gcccgcgtgc aggtgcacgg catcgccgcc
     9121 cattccggcg gcagcagggc cgcgccgtcg gccatccaca aggcggccga ggcgacctcg
     9181 cgactgcacc gggcgccgct gcccggtccc ggcgggccag gcttcccgct gccgccgaag
     9241 ctgaccgtca ccgcgatcca cggcggcgag ggctactcca ccatccccga cctctgcatc
     9301 cttcacgtcg atatccgcct caccccggca ttcgaggccg agcaagcgct ggccctgctg
     9361 cgctcgacgc tcgccggtct ggacgcggat tggccggaca ccccgccgac caacctgacc
     9421 gtcaccaccc ggtggcccgc cttcgccctg cccgagcacg agccgctgcg cgcggcgctg
     9481 ctggcggcgg cccaggcaac cgggctccac ccgcaggcca aggtggccgg gccgtccaac
     9541 atcggcaact acctggccgg gctgaacatc cccgccatcg ccgggttcgg cgtggactac
     9601 cggggcctgc acgccaccga cgagcagatc cgcctggact ccatcccgcc cgtgcaggcc
     9661 acctatcacc gagccctgct gtcgctgctg ccggcctgct gaccggcggc ccacccggtg
     9721 gcgacgccaa cgcatcgaca aagggtggac aacgcgtaag ctggcccgct cgcggcccat
     9781 gggtgacggt gttcctacag cgagtaatcc ccgctcgctc ggtgcaggcg actgcgccac
     9841 cccgtcacct ggaggatgac catggatcac cccacgccgg ccggctatga ggctccgcac
     9901 ctgagccccg tcggctcgtt cgcgaccagc acgctgggta gctacagcaa ggacaccagc
     9961 gacgactccg acgccggcca gtactacccc agctgagccg atgaccaccg ccgcgcacag
    10021 cgcctggttc gtggccctgc ccgacgcggc catcgcccgg gcggccagcg atacgctgct
    10081 ggccgcccgt ggcggcgtgc tcgcccgcca cgcctcggga cggccctgga tcatcgggta
    10141 cggctaccac acccccgccc cgccccagcg atacggcgac gagctgcgca cggccgccgc
    10201 gggaaggctg cggatcgcta tcgccggatt ctgccctgcc cccgaccggg aactccggcg
    10261 cgccgccgcc caggccgggc gcggccgtgt cgaggacctg ctgcggctgc cgggcagctt
    10321 ccacctcatc acctgtgccg aggggcaggt gagcctgtac ggggacgtgg ccggtctgcg
    10381 acgcctgttc cacagccgcc tcgacgacgg cctgcccgtg gcgggtgacc gggccgccgc
    10441 cctggcggcg ctgaccggcg gcgcgcttga tgagcgctgg ctgggcgccc ggctgctgaa
    10501 cccggagatg cccgccgatc tgctgtggtc gcgtctgtca ccctaccgcg gcgtggtgcc
    10561 ggtgccgccc ggccaccgcc tgcgcctgga ccatgacggc gtcagcgccg cctgctactg
    10621 gcggccgccg gcggcggtac tgacgctgac cgagggcgcc gagctgctgc gcacggcact
    10681 gtcgcgggcg gtcgaggccg ccgtgtccca agccggccgc gccagcgtgc aactgtccgg
    10741 cggctgggac tcggccgcct tggccgccct cgcctgccgg gcccgcccga aaggcggcac
    10801 actgctgctc accgtggcct cggccacggc cgacaacccg gacgtgcgct gggcccgcca
    10861 caccgcgaac cggctgcgcc cagccgagca ccaggtgctc gaagcctgca gctacccact
    10921 gctgttcgac ggcctggccg agccgatcgt gaccgacgag ccggcctcgt tcatggtctc
    10981 cagcgcccgc atccggcacc tgaccggcgt gctgacccgg tacggcagcg ccgcccacct
    11041 caacggccaa ggcggtgacg aagtactcct cgcgcccctg gcccacctct tcgatctgtg
    11101 gcggcggccc ggactggcct ggcatcacct gcgcggctac gccgccctgt ccggcgtcgg
    11161 cacgctgccg ctactggccg ccctgctacg cgcccgcccc tcatggcggg gtccacggcg
    11221 ggatgcgggt ggcgcgtcgc tgcggtgggc accggcttct gcccggccga cgttccggcc
    11281 gacgctggtc accggctccg aagccgtgcc cctgctaccg ccgtgggcca ccgccgccgc
    11341 caccgaacag gcggccaccc tgctggacat gctcgacccg cccgagggcg atacggtcac
    11401 gcacgccacc gtgacccgga tccgcgcctg cgcccgccgc gccgccgcct accgcgacgc
    11461 gctcgcccag cacgacgtgc ccgcgcactt cccgtacttc gatcaggcgg tcatcgacgc
    11521 ctgcctggcc acccggccgg aggtgcgcac caccccctac cagcccaaac cgctgctggc
    11581 cgccgccctg gcgccgatcg cccccggcct gctggtgcgc cgcgacaagg gccaccacaa
    11641 ccacgacctg cacgccgggc tggccgcgca cgccccgcac ctgctggagc tgttcggcga
    11701 cgactgcgcc ctggcccgcg ccggcgtcat cgacgcagcc ctgctgcggc gagccctgac
    11761 cggcaccggc ccgtccagcg tggccggcgg gctgccgctg gcgttcctga ccgagaccct
    11821 cgccatggag ttgtggctgc gccaccgaac cggaggtagt gatcatgtcc tggaacctgg
    11881 ccccggccgt gcgccggacc ggcgcgctgc tgtttgacgg cggccgcggc ggctacttcg
    11941 cgctcaaccc caccgccacg cagacgctgg aggtcctgct gaccggcggc acctgcgagc
    12001 aagccgccca agagctcgcc gcggcctacg ccgtcggcac cgaacgcgcc ctcgccgacg
    12061 tggcggcgct cgtggccgac ctgaccaacc ggcaactact gaggcaggca ggatgagcac
    12121 gctggtcgcg ctgcccgaac ccatcgccct gaccggacgc gagcagttgc gcggccgaac
    12181 ggcgctgctg gccacccggc tgctgctggc ccgccaccgc tcccacccgg accggctggc
    12241 cgcgcatctg gccgtccgag cccgaggctt cagccgggct acggcgcagc aggcccgcca
    12301 cgctcagacc gtcatcacca cgctcagccc acgctgcggc agcggacgcg gctgcctgcc
    12361 ccgctccatc gccaccgcgc tggcctgccg cgcactgtat ctgacatggc cgacctggcg
    12421 cgttggcatg cgctacccgc cgctgatgtc ccacgcttgg gtgcaggccg acggccagcc
    12481 catcggcgat gaccccgagg tcatcgccgc ctacacgccg acctacaccg tcggcccgga
    12541 aggagcccca tgaccaccgc ccccgccacc gagagcacgg ctggccggat ggcccgcctg
    12601 gccgagcagc tgcgcgagct cggcgccatc cgcaccgacg ccgtccacca cgccttcgcc
    12661 accgtgcccc ggcacctgtt catcaccggc ttctacaccg gcggcgacgc ctacacccgc
    12721 ctcggcgacc cgcctggcga cgacctgctc gaccagatct actccgacgt cgcgctgatg
    12781 acgcaccggc ccagcgacgc ggccggacgc ccgtcctcgg cctcgatgcc acgcgtggta
    12841 gcccgcatgc tggaggccct cgacctgcgg ccgggcctgc gggtgctgga gatcggcgcc
    12901 ggcaccggct acaacgcggc gttgatcgcc gccatcaccg gcgccgacgt ggtcagcgtg
    12961 gacgtcagcg aggtcatcgt cgccgaagcg caggcggccc tgcagcgcgc caacgcgagc
    13021 aacacagccg cgtacgtcgc cgacggctac ctcggacacc ccgaccgggg cccgtacgat
    13081 cggatcatcg tcacctgcgg catcaccggg atctcgccgc gatggctgga gcagctcgcg
    13141 cccggcgggc tcatcctggc ccctatcgct cacgccggat tccaccccac cctggccatc
    13201 acgctcgatg gcgccgggcg gcccatcggc cgcgggatac tgtccagcga cttcatggcc
    13261 gctggcggcc ctctctacgg ccggcccgcc gaccagacct cgccgcccgg cgaggtgccc
    13321 gccgacggtg ggctaaccgt ctggcccggc actgttcccg ccctggccga tgaccgctac
    13381 ttcgacctgt ggttcgccct cggcgccgcc gacccgcgta ccatccgcgc ctacacgccc
    13441 ggcctggacg ccgccctggg catggtctgc ctgcacgagc ccggccgcgg caccgcctgg
    13501 gtgcaacgcg acggcgccat ccgcttcacc ggccaccaag acctcgccca ccaactgacc
    13561 gccctcaccc agcaatggga cagcgccgac cggccccgca tcagcgactg gacggccggc
    13621 ttcgtcctgt ccgaggcagc cgacccgctc tggcatccgg cagcctgggc acgatgagcc
    13681 cagtccgccc actagccatg cctgacctgc tcgctgccgc ctgacctcgc gccccgtgca
    13741 tgcctgcgga tatctggtga ccgggaagct caaccgttcg ccagatgtcc cggcggcccg
    13801 gggcaatact ccctgcatga cggacccaac tcccttctcc cgagtcaaga tccgtcaccc
    13861 ggcctcgatc gccagcatcg aacgcaggtc cgcgacagcc gggcgggcct gctgctcgac
    13921 gggcaccgct tgcagcacca tccgggccgt ctccaccacg tgggtgctgc ggaaccgagc
    13981 cggcacggcg gccaatacct ccgtcgcgcg gccaagcccc tgatcgacac cccccctgag
    14041 cgatgaccgc ccaagcgcca tgaagctcaa cgttcacctg gtagacgtag tctcccgcgt
    14101 acccgcgcac ggcctcacga gcctgcgccg cagcgtcctc catccctgcg gcgctgtaca
    14161 cccaggaccg ggtgaaagcg attgcgtccg gctgccagaa tcccaacctg tcaccgtgcg
    14221 ccccctgctc agcaagagcc accagtcgac ggagcacgtt gagggcttcc tcatggcgac
    14281 ccatcatgga cagggccttg gcctcggctc cgatgagctt gagcaccggt tttccgccag
    14341 tgaggtggcc ggcctcggcc acacgccgca ggatggtttc tggcgactgc tgcccgtaca
    14401 ggccatgacc ggcctcctcc gcgcgaacca gcaaccgcag cgccaggtct cgtgaggcgt
    14461 cggcggccca gcgcgcggcc tcccaccacc ggatggctgc tccgtgctgc cccatgcggg
    14521 tgagcacgtt ggcgtggatg gcagcgagca tcgcggtcgc cctatgcagc tcgcgccgtt
    14581 cctcgacgcc cgcgctctcc atctgcctcg ccagggtgtc caagtcgacg gcgacgtcgc
    14641 gggcgacctg gagggccgga cgggtccgaa gcgcgtggag atgcccctcg tggacgacgg
    14701 cccattcctc ggtgctgcgg cgagcgccta tcacggtgtt gagccgtcgc cggacgactt
    14761 ctccgtcaag ggccgctccc aaagcagtac cggcggctat ctgcagcagg cgacggcgtt
    14821 ccgtggtgtc ctccccgtca tcgacgtcat cgaagcccag agtacgcacc gagcccatct
    14881 cgtgggtagg ggggcgaaac tccgcatgct gtccgagaac ctcatatctc tcgtgaacag
    14941 caagaagctc gccattcgca cacaaggccg tatcgagcgc gacggcgatt cgccgtgtcg
    15001 ggtttctacg gcctttctcc agatcgtcaa tggtggattt gcccaccgct gctcgttgcg
    15061 cgagggcacg aagaggaaga tccgcatcct gccgcagacg gtggagcacc tgtccgaagg
    15121 tctctgccat cagtgtccgc ccacctgacc tgtgtctgct agtgtccgcg gacacctgcg
    15181 gacatctgcg gacgtgccga ctctagcccc gacctgctgt ggtggtcagg ctactcgtac
    15241 gccccatgaa cgcccatcga atcgggaaag gcgttccacg aaaaccgccc gacccccatc
    15301 ccggagattc ccatgctgca cgcgaaggca cccttcacaa ctgttttcac ttggcggctc
    15361 accaatgacg ccaaccggga aatatccggc gtgacgggcg accaattgcg ggccacgcac
    15421 cacctcctcg acgccttcaa gctgatgccc ggtgttcccc ttcgagggga gctccgcatc
    15481 gccggagttg acccccggga agtctcagtg tcctacctcc gcacgcacct gctgatccgt
    15541 gtgcgacgtg acatggagac gggtgccgtc atctgcgcac ctcagccagg attcgccgca
    15601 cccatatacc ggcgtcgccc cacgagggcg tatccctccc ggacagcccc cggcctgcca
    15661 gctcggaggt gcgcacggct ggccgggggc gccagttcgg aagtcgtcgc ctcatgaagg
    15721 cgttgcgcga ctggcgcaac ctcgacggcc actcattcga tgaggagctc ttcgccccca
    15781 tccggcctgg tgaggagaac gggctggagt tcgtgccgat cgccggagcg gaaggagtcg
    15841 cggcgctacg tcggcccagt cagccgcacg ccgtgctgct ggtcaccgcc ctggaactcg
    15901 acaccctgct ccacctgctg cgctgccgct aagctccggc gccccgtcgc ggctcacgcc
    15961 ggatgctcgt ctcttccgag atgagatgaa cacctccacc aacgtggagc aggtggccag
    16021 ggctacgacc ctcgtccggg ccttggccac ctctggaact cgccacgtct gctgctggcg
    16081 agcacaaccg cggacggccg gtttcaccgg gatggcgccg gccgtccacg actcctggaa
    16141 gacaccacca gccgaacgag aggactgcca tgacagcgaa agacagatgc ccggccgtgg
    16201 tcgagcgtgt caacgaccac gtggagatgc gtgtcgatga gcgcgtgctg acggcgagcc
    16261 tggacggctg ggcgcagttc ctgcgcgccg tgcaggacgg caagccgacg gacgggtccg
    16321 tccgcttgcg gacggacgtc gcgcacgcgg cgacgctgtg gaacgtcgag gccgacggcg
    16381 acccgctgaa cctcaacgcg gaggagtggg cgacggtcag ggagcacatc gagcgcggcg
    16441 acttcgacct ggagaagctg ccgcgtcagg cgcaggagcc ggacaccgtc gcctgacgac
    16501 gtcgcctccg cccggcgcga ttgtcccgcc ctttcgcgcc aggcattccc gccctggaca
    16561 cgggcccggc cagggcggct ggggccgaga ccgctcactg attccggcgg tctcggccct
    16621 ccaccgtctc cgagcacacc acatccgaac acacgagcca ggaggatcgc atgaccggca
    16681 cgacgctcat ccgggccgct accttcaacc tcaacgatgg aggcatcgac gacggacagg
    16741 acgacaggtg gtgcaggcag ctcgacatgc tggccacgct cgacctgcac gtgctcgccc
    16801 tgcaggagct caagaacgac gaccgcgacg ggtggcggcg gctgcgtcag gccgagcggg
    16861 cgctgggcat gcacgggtac gcggtgccct ccaaccatca cggctgtcat ccgcagaaag
    16921 tacgatcggc gcccggcgga agaactcgaa gggacggggt tgcacgacgt cggcgcgatc
    16981 ctcggcgaca gcgacccgac cgtgggacat ggcaacggcc cggcctaccg gtgcgaccgc
    17041 atccacacca ctctgccgcg cacgtcgatg gtcagccacc gggtcatcca cgaggagcac
    17101 ccgacgtcag atcatcggcc ggtggtggcc gagttcgagg tctgatcgtg gctctggtca
    17161 caggaacgag cgccgagccc ggacctccag acccgaggcc gcggtggtcg acgtggctgc
    17221 cgcggtgatc aggaccgtcc gcgagtgtgg atcgcctacc gcgatcgcgg gcgtgaggtg
    17281 gagccaccga gacgcgcttc cagggccagc ggcggtgatc tggccggtca cgtccgcgcc
    17341 gcccgtgaaa tcccacgtgt ctgtcgtgac gagccgcgcc cgcatctgcc cgcagtcgat
    17401 cagcagccgc tctccggcga gcaggccgga gggccgaccg acggtcgcgc cggtggcaac
    17461 gtcggtgaca acgtcggtga cgctcaggtt gacggctgga ccggtgacgc gcacgagcgc
    17521 gtccacgatc cggccggtcg aacccgccag cggcgtgatc ggctggctgg cggcgttcgc
    17581 cgatcccgtc cacactgctt cgatggggtc ccgccagtac acggcgggga tcttgacgac
    17641 tgcggtgagc cgggctcggg ccgccgaggt gttgatctcc ggctccgaca ccgcttcgac
    17701 cgtgacctgg gcgacgcgca cgatcgatcc ggcggtgtag gtgaggtcca tcagccggtg
    17761 gcggacgccg agcatggccg agatggcttc gaggttgcgc tccagttgtt cgaatccgcc
    17821 ggccccgccc gacggggtgc ggccggtcac tccgatcacc agcggcagcg tcgtcgtttc
    17881 cagatccagc ccgtgcaccg gcagctcacc ggcgacgccg ggcactttga ccgacaccga
    17941 gcgcacgccc ggcaaggggc ggcgcttggt gccgaccttg gtccgccagc acccggccgg
    18001 gtggtccagg gcgaccccgt cgagcaggta tgtcggcatc agctcctcct acttgtccat
    18061 ctcgacgcag aagtcctgtg atcacgccct aggcagacac tttcgccgct tctaggctgc
    18121 gctcgtgacc gacatcagct acttcgacgc atggcagcta tggttggacg gcaggtccac
    18181 cctcggcaac gatctcctgg gcatgcagat gatctggtgg ggacgcggcg ggaagatcct
    18241 cagcttcctc agcggtgtca ctatcgtggt tgacctcgtc ggccctgaga agttctcccg
    18301 ttacggtcat tggatccagc gtcttttgaa cgtgcaggtg tggcattttc ccgtcgtacc
    18361 gtttgtggtg gggggcgtgg tcggcgtcct tacgccgtcc cgcctcgaca cggagtcgat
    18421 cgtcgcgaac cttatcggct gggcgatcgg ggtatcactc gtgctgctgc tgcttcggtt
    18481 ttccttcctg ctgatcaatc cgcagatggc gttgatcatc cggtggatgt cgctcggact
    18541 cttcgtcgtg ggctttcact tcgatctgct cgcttcatag ctgagaacgc gcgctccatg
    18601 cggcgcctac agcaccccga gcatcccggc gtaggcgagg ccgcggttga cggtctcgct
    18661 cgcgggttct gcgaccggat tgatcgccgt cacctggatg gttacggacc ctccggcgcg
    18721 gttcggcgct cctgtgacaa tgtggccagc cgaaccaaga tccacggcca atcgcggccg
    18781 gaacgatcgc tcaatgtccc cggagatccg tgtcacggtg gccagtaccg tccgagcgga
    18841 ggtctgcatg ccctccgcca tgcctagcat cgtgaactgg ccgatctcgg cgaacaaagt
    18901 ggacggcgag ctgatgccca tcgccgcgcg cacccaatcc ggcaggatgt tgcggaagaa
    18961 gccccagatc acgtcccgga accacccggc cgccgcttgg attccgttcc acagcccttg
    19021 caggagctgc cagccgaggt tgtcgatgac gacgaggaag tcgaggatcg cgcgcccggc
    19081 ggtcgcgagc gcgccgacga gatcgccgcg cagcagcagc gcagccgatt gcaccagggt
    19141 gatcagcggc tgctggtaca ggccgcgcgg aaggtggatg cgaacggcat gcggaagctc
    19201 gacgaactcg gcctgaaggt cgtaggcacg ctgcatcgtg gcgtcatgct gggctcggtc
    19261 gccctcgtcg agatcacgcg cgacagcagc agcccatggg ccaagccgtc ccagcaccat
    19321 tggcagctgt ccgacccgga gccggccgtg cggttgctgg gggtgaaggg gcagcaaggt
    19381 cggctgttcg acccgccggc ggactggcgg cgcgggttcg cgcagcatga tgcgcacgga
    19441 acccggctgt cgcgagtgcg ggagatgccg ccagaggagc gagggtcgcc gttcaggggc
    19501 gaaggtagac cctgccgctg cgctgctggc cgcgatcagc tggccttgac cggcgacggg
    19561 gccacgtact cgaacgagag cacgccgagc cgccgggggt cgagggactg ttcatgcatc
    19621 caggcgtgct tgctggtggt gccgagcttg cggtcctggc gctgcacgcg ccagcgaggg
    19681 ctccgggccc ggtaggcgtt caacgcgggg tgcgaggaga cggcgcgcat gcggtagccg
    19741 cgttcgtaca ggtattggcc catccactcc gtcatccggc cgcccagcga caagccctga
    19801 taatccggca gcaccacggt acggtgcgcc attttcagat tcctcgtacg ggggtgctgg
    19861 aaatgacggt agctggtaaa cgcggccagc tcgccgtcca cgtagccgac gaagcattgc
    19921 gcggccgggt gcaagtcggc cgtcagatag tgatggcggc taaacacgga ccagagggag
    19981 cggtccgcct ggtgaatggc gaactggagc gggggccggg gttgaaccga cctccaggtg
    20041 aactcggcgg cggcaacgtc gtaggtccag tccggctgca gccactcctc gacgtcgtag
    20101 tggcaggtga cggcgacgag ctgccgcttg cgacggcgga ccgccttctg tgccgcgtgc
    20161 gacgcgatgc gcgcgacctg ccggtccacg acgctggtga actcgtcgat gaccacgagg
    20221 ccctcgtgct cggccagcgc ccgcgccagc ccagcgcgga acgcctcccc attcgagagc
    20281 gtcgcataag acctgagcca tgccggcggc gagttcaggc caaccgtgcc gagcaggccg
    20341 acgacctcct tgatcgacat gttcttcggg aagtcgtcca cgagcgctcg gtcactccag
    20401 cactgactgc cgaccagcgc gtcgggccag agcttgcggg cgatggtgct cttacccgct
    20461 ccgctggggc cgacgagcag gccgacgttc cacgtccgtt cctcgatggg caggttgacg
    20521 ctccacgagc cggccagctt ctcgctgatg ggcacgtcga acaggccctg caactggagc
    20581 acccgcgcgc tccgcttgac ggacgacgac aaggtgatct cagcctgcac atcgatcccc
    20641 tctctcgtag ccgataggaa ggagcagaat gcggatgcgc taaacgagcc acatctctag
    20701 cctcggcaga gtgacgaccc tgaaccatga tcagctactg gcttccgcaa gagatttcgc
    20761 gcatagggcg ctgcgggcgt acgtcgaaga tgaccagcgt gtgattctga tcaatgcagc
    20821 cttctccttg gagcatctca gcaaggcata cctgtatgcc cagcatccag ccctcctcat
    20881 ggaggtacgc aacgggcaat tcgactcgtt gctgcatctc actgggctgg gcggcaaggc
    20941 gcgtaagctc aaggcgcctc gtacgatcag cgcgaaggaa gccctggcga gagtcgagca
    21001 actgatgact ctaaggacac cgcgggcagc cctcgatgaa ctcatcgatg tgcgtgatgg
    21061 cgtcgtgcat gtggggtacc tgagccagac cagtactcgg gagatcttga ccgtattcct
    21121 gcggttctcc aacgagctct atgaggagca aggcgtagat gagtccgctc gttggggtga
    21181 tcactcaact ctggtcacct ctctcattac gcaagccttg tccgagatcg agcacgaggt
    21241 tcagcgcaag atcgcagcgg ccaagcggcg catcggggaa ctgatgagca agatccccga
    21301 gtccgaacac gtcgctgtgg gggacgcgag gcaggcgatg acgcctttcc agcgatatct
    21361 cgaccaggaa gccagcgcaa gcggctctcg tgatcatcgg atcaccattc gatgccccgc
    21421 gtgcaaccat ccggacgcct cttgtatcgg ccacatcgag tgggacttcg acatgccagc
    21481 tgagatcggc tcgatggacc ggattgagga ggtggccgga caggaagagt attttctccc
    21541 acgggctctg ctctgcggct cctgcgatct tcgactggat tccgaagacg agctgcaggc
    21601 ggtggggata ccgcgtcgcg tggtgttcgg aggcagagga cttcagctcc agtgagaacc
    21661 gggcgctgcc cacacgtcag gaagttcagc agttgccaca cacttcttat ttcatctagg
    21721 tatgatagtg gcatggcagg tctcgaacgg atcacccagc ccaccctcga cgtgctcgaa
    21781 gtcctcgtca cggcccacga ccggaacgag cgagttcacg gctgggcaat catgaaaaca
    21841 accaaacgtg caggtccgac cgtctacaag gtgctcgacc ggctggagga tgctcattgg
    21901 gtcgtcggcg agtgggaaga actaggacct gaccaacctg gcccgcgtcg ccgcttctat
    21961 cagctcacgg gcgaaggggc acctgctgct cgcgctctac tcataaagcg ccgcccatcc
    22021 gcacttcagc cccgccccgc taccgacttt gcttcgctct cgaagctact tggcttagcg
    22081 ttcggaggca cgcgttgagt gacctagaga ttctcctcag cgtcgtgctt ggtctcctgg
    22141 tgaatgagac atgcgacgtc tctccatggc tcgcgcgaaa gctcgttgta agagccgcca
    22201 atctgcagta ccgggaccag gagcgggcga cggtgcgtgc agaagaattg gccgcagtaa
    22261 tcgaggagcg tccaggcaaa ctgctcaagc tcgccaccgc tttggccttc atcgctggcg
    22321 cgctagcagc tcgactgttg cgtgtagcac agatttctac aaagacaata cgtctgtgga
    22381 ttcatctctc ggtagcttcg tggaaggttc tctatctgtc agtccgcacg agtaggacag
    22441 aaaggaagat gaagaagctt ctttgtgaac tggccaacag agaaggtaaa ggtaaatcta
    22501 gcgctgctgc ggcagcagct cttctagtcc ttgaaggtgg cagaaaaacg gct
//
