LOCUS       NZ_CP017717            26410 bp    DNA     circular CON 03-MAR-2024
DEFINITION  [Actinomadura] parvosata subsp. kistnae strain ATCC 55076
            chromosome, complete genome.
ACCESSION   NZ_CP017717
VERSION     NZ_CP017717.1
KEYWORDS    RefSeq.
SOURCE      [Actinomadura] parvosata subsp. kistnae
  ORGANISM  [Actinomadura] parvosata subsp. kistnae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 13047416)
  AUTHORS   Nazari,B., Forneris,C.C., Gibson,M.I., Moon,K., Schramma,K.R. and
            Setedsayamdost,M.R.
  TITLE     Nonomuraea sp. ATCC 55076 harbors the largest actinomycete
            chromosome to date and the kistamicin biosynthetic gene cluster
  JOURNAL   Medchemcomm (2017) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13047416)
  AUTHORS   Nazari,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) Chemistry, Princeton University, 20
            Washington Road, Princeton, NJ 08544, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUN-2015
            Assembly Method                   :: Celera Assembler v. Jun 2015
            Assembly Name                     :: SmrtPipe 1.87.139483
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 13:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 12,000
            CDSs (total)                      :: 11,919
            Genes (coding)                    :: 11,783
            CDSs (with protein)               :: 11,783
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 36 of 136
            Pseudo Genes (incomplete)         :: 98 of 136
            Pseudo Genes (internal stop)      :: 10 of 136
            Pseudo Genes (multiple problems)  :: 6 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:57:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3167161
            Orig. end                         :: 3193571
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017717.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26410
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /product="RRE-containing"
                     /region_number="14"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..26410
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="neighbouring"
                     /product="RiPP-like"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..12229
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12229
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7229](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7229)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(547..561)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 20.47"
                     /tool="antismash"
     gene            665..1441
                     /locus_tag="BKM31_RS14330"
                     /old_locus_tag="BKM31_14190"
     CDS             665..1441
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013899.4"
                     /locus_tag="BKM31_RS14330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14190"
                     /product="urease accessory protein UreD"
                     /protein_id="WP_230466158.1"
                     /transl_table=11
                     /translation="MPVEPGPGVRATARIRAARAGDTTVLPVLAGDGPFDLRRTRPQGN
                     RARVCILGVMSAPLGGDRLRIEATAEPGAHLHITTAAATIALRGPTTAHATYDVHLRVA
                     EQASLHWLPEPLISAARSNLRQSCTIDLAADARLVLREELVLGRSGEPPGRLTTRLTVH
                     RDGRPLLDQQNTYGPDAPGWDGPAVLDGHRAAGQLLIVDPAYDKEPPAVRLFGDDPAGG
                     QAVLTPLAGPAVLITALAPNTLRLRHLLDAADPLGR"
     gene            complement(1400..1618)
                     /locus_tag="BKM31_RS62360"
                     /old_locus_tag="BKM31_14195"
     CDS             complement(1400..1618)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS62360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_14195"
                     /product="transposase"
                     /protein_id="WP_230466159.1"
                     /transl_table=11
                     /translation="MQGQNSPVFALATLFGFDLMRVAISISEGRLSSATLMRRLRSDSR
                     KNRISETFREAGRSSSAEGVGCIEEVA"
     misc_feature    1864..1878
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            2384..3646
                     /locus_tag="BKM31_RS14340"
                     /old_locus_tag="BKM31_14205"
     CDS             2384..3646
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="BKM31_RS14340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14205"
                     /product="MFS transporter"
                     /protein_id="WP_186403934.1"
                     /transl_table=11
                     /translation="MEQQKGWRTRLLESVELQTGPRRVLAISTLVNTTGSGLFLTAGAL
                     YFTRVVGLSVVEVGAGLTIAGFAALAAGIPVGRMADRWGPRRLWAMFLVLEACAMAGFL
                     FVNSFPSFVVMACASQFAAAASQTARMPVFRRIGGAGATRLRAVIRSLVNVGTSLGALA
                     AGVVITIDTRFAYTVLILANAISFAVNVFLVLLLPKLDPLRAKSESTTGVALRDRPFLA
                     ITVLNGILALQGPVLTFAIPLWIVQNTAAPRSIFAILVTINTVLVALFQLSATKGIDNV
                     IKAGGAARTASIGLFLAFFLFGWASGFSATVATVLLIVGVVVLTLAELRYAAAEFELSF
                     GLAPAQLQGEYSGVFGLGQGLAASAGPYLLAVLVLGGAGITGWIVLGVLMVAAGLLVPA
                     AVAWAERTRSHEPEAGSEAKA"
     gene            complement(3720..4928)
                     /locus_tag="BKM31_RS14345"
                     /old_locus_tag="BKM31_14210"
     CDS             complement(3720..4928)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981770.1"
                     /locus_tag="BKM31_RS14345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14210"
                     /product="cytochrome P450"
                     /protein_id="WP_230466160.1"
                     /sec_met_domain="p450 (E-value: 5.5e-32, bitscore: 110.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETAFTFPTGKRPGPFDPPDVFASIREQHPLTPMTFADGHEGWL
                     ACSHRIVRKILADDRFSNRRELMHLPVDRDISKKRQPSEPGMFIRMDPPEHTRYRRLLI
                     AQFTVHRIRQLEPKISAVVRSCLDAMERSGPPVDLVEEFAVPIPSAVICDLLGIPESER
                     AEFQRAMGVAVDLNTKQADLIEAFITMQSLFPPLIASKRARPTDDFYSDLINNSDLTDE
                     ELTNIGFMLFGAGFETTANMLGLGTFALLEHPAQVAALRQDPSLIDSTVEELLRYLTII
                     HIGPMRAALEDVDIEGVTIKKGQVVCMSLAAANRDPACFDDPDSLDITRYARAGKRNMG
                     HLAFGHGIHQCLGQQLARAEMRLAFPALFERFPGLRLALPPEEVPTRQAAVIYGVQRLP
                     VTW"
     gene            complement(5001..7229)
                     /locus_tag="BKM31_RS14350"
                     /old_locus_tag="BKM31_14215"
     CDS             complement(5001..7229)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03975.1"
                     /locus_tag="BKM31_RS14350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14215"
                     /product="RiPP maturation radical SAM C-methyltransferase"
                     /protein_id="WP_186403935.1"
                     /sec_met_domain="TIGR03975 (E-value: 7.6e-169, bitscore:
                     562.3, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.3e-16, bitscore: 58.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVSSEFSGEQRALLTRTFIDPAFREALREDVSAALRAAEIDPAS
                     ALGGSLREEIEGFFARGGGARLGRSATMSLDIAAANPTAQDSTGQGSTGQDGTASPRVA
                     FVVMPWAETRWASIGVSLLQSALTASSIASDVIYANLDFAEAVGNTMYNRIGTSSPKVA
                     LVGEWLFTEGSVEGADGGERFLNEVLLDEHGGFADFATIFQLGEIKALTAPFLDALARH
                     EVWERYDLVGLTSTFQQNVAALGFARRLKQLHPHITVIMGGGNCEGPMGSAILRNYPAI
                     DYVFRGEAEWLISRFVSDFRAAGGRPGWIEADPFWSARAEPQPGGRAVIVAGTAPSMDD
                     LPVPEYHDFYTRLRASGPGSSLPVDTAVPLETSRGCWWGEKKHCTFCGLNGMTMAFRSK
                     SAARAFDELRKLVHDYGPGPKRRTNVLVVDNILDYRYFNDLLPMIAQSDLKVSLHYEVK
                     SNLRLDQLMLLRDAGVHHLQPGIESMSNRLLEAMRKGTTRLRNLQTMKWCAELGIDVSW
                     NYLHGFPGETDDDYADLPQLFSLVPHLSPPEHVGPARADRFSPFYESGADFGIVELTHE
                     RAYDHVYADLPSAERRDIAYFFRMRCDEPLASEPVLAAMSAAAERWRQDHAEARLEASW
                     TDDHLRVIDTRPARPRPETEFDLDPAASAVLLALDQLRSAQAIERALPVPVPATEIAGA
                     LERLLKAGLVVRDGDSYLALPVLNRRRLPSPKPAVRVPRDLPLLTGTT"
     cand_cluster    6120..26410
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    6120..26410
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[16119:16410](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(16120..16410)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="2"
     misc_feature    7322..7337
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.34"
                     /tool="antismash"
     misc_feature    7513..7526
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            7685..8548
                     /locus_tag="BKM31_RS14355"
                     /old_locus_tag="BKM31_14220"
     CDS             7685..8548
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (47-274). E-value: 2.8e-13. Score:
                     42.2. Matches aSDomain:
                     nrpspksdomains_BKM31_RS14355_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.4"
                     /locus_tag="BKM31_RS14355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14220"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_186403936.1"
                     /sec_met_domain="TauD (E-value: 5.6e-11, bitscore: 42.2,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEICLSEADRRELAEVASVVVGWSLDGPSIEALRERAGQSESLR
                     SIGLDVRRRMREDGFALVKNVPCSEDAELVAFLGLIAIPSAPGNGDTLFFDISPSSSRS
                     DDVSGTSAEFPLHTDSTFFSVPHDVLALACVRNSDSGGESIIVRAADVADRVRAIGGAD
                     ALAALGDQVYPFYLRDPLFGHGIQLVPILVADGDEWCIRYRGDILAKLTERFELDEVHR
                     HALSVLNQVVAEPESGAVQVRLETDDLIIVDNRRALHARTALGPGERRLRRMKGYSLDN
                     SAWRII"
     aSDomain        7826..8506
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS14355_TauD.1"
                     /evalue="2.80E-13"
                     /label="BKM31_RS14355_TauD.1"
                     /locus_tag="BKM31_RS14355"
                     /protein_end="274"
                     /protein_start="47"
                     /score="42.2"
                     /tool="antismash"
                     /translation="GLDVRRRMREDGFALVKNVPCSEDAELVAFLGLIAIPSAPGNGDT
                     LFFDISPSSSRSDDVSGTSAEFPLHTDSTFFSVPHDVLALACVRNSDSGGESIIVRAAD
                     VADRVRAIGGADALAALGDQVYPFYLRDPLFGHGIQLVPILVADGDEWCIRYRGDILAK
                     LTERFELDEVHRHALSVLNQVVAEPESGAVQVRLETDDLIIVDNRRALHARTALGPGER
                     RLRRM"
     gene            complement(8671..10497)
                     /gene="asnB"
                     /locus_tag="BKM31_RS14360"
                     /old_locus_tag="BKM31_14225"
     CDS             complement(8671..10497)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /locus_tag="BKM31_RS14360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14225"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_080038619.1"
                     /sec_met_domain="GATase_7 (E-value: 2.2e-38, bitscore:
                     130.3, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.4e-63, bitscore:
                     214.4, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="QueC (E-value: 5.6e-06, bitscore: 25.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTATRLGAAVCGIAGVVRWGRDTADLRTVERLLTAFEHRGPDSR
                     GTVSSGPAALGAVRLSLVDVAGSDQPISYRAAGVHLVFNGEIYNHARLRKDLESAGHRF
                     LTCGDGEVILASYLRDAESFTERLDGMYAFAIWDARRETLTVGRDRMGIKPLYLYAAQD
                     RLVFSSELRSLVADPHVPVEVSRDAAADYFTVRFSPPACSPLTHVRKIEPGTTVVFDRQ
                     RPSGMVRESRWLRFPAFSAAREPQGCLATELRESVSTTLPPDAPAAAFLSGGLDSATVS
                     ALAAQQRGTIDVFSVGYAANTWQDETGYAGEIARHIGARHDITHLTESNVQETFLATLR
                     SMDEPIYTPVCLSTHAVSGLAARQHKAVLAGDGSDELLMGYAHMHEAHQAALRGEPWRD
                     RYWNALGWWTDDDRRRVLDDDMLKRCAPDVSQERFGFAGLAAGGADAAEVIRWFEVTAK
                     LPGYHLPRVDQLSMTHGLEVRVPFLRDGVVDWALARPARSLMTGRPKEVLRSVARGLVP
                     ASIVDRPKQKFSAPASVWLAGPLRDLTLDLLHEGAGAEELGLEAAGLARLAGDFHRDPS
                     ANTRTVWGIVVLLGWYRALREHIRQARGAGAP"
     gene            complement(10566..12086)
                     /locus_tag="BKM31_RS14365"
                     /old_locus_tag="BKM31_14230"
     CDS             complement(10566..12086)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012398.4"
                     /locus_tag="BKM31_RS14365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14230"
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_080038620.1"
                     /sec_met_domain="Aldedh (E-value: 1.6e-179, bitscore:
                     596.8, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATDAATEPRTPADVEQYRMLVDGVWRDASGKATFDSVNPFTSQ
                     PWARVPAASEQDIDDAVQAARRAFETGPWAASTPLQRAALLRRLGDLIGDNADELARVQ
                     VLENGRLVREVGGRAKSLANHAYFFAGVAESPTGETLAGSVPNMQIFTVREPIGVVAAI
                     TPWNSPLTLLLWKLCPALAAGNTVVIKPSEITPVSTLVLARLLCEAGFPDGVVNVVTGA
                     GDAGAALAAHPGVDKIAFTGSTAVGKKIAGIAAERLARVSLELGGKSPNIVFPDADLSS
                     AVNGVVGGVFAATGQLCMAGSRVLVHTDIYDEFCDALVARTERIRIGDPMDPATEMGTM
                     ACRAQYDKVLHYIDVAKQDGARLATGGDRPDDPALARGLFIRPTVFTHVDNRMRIAREE
                     VFGPVAVVIRFSDEDEAVAIANDTRFGLAAGVWTKDLARAHRMVRRLRAGTVWVNNYRR
                     TNHVAPFGGFKESGIGRENGFHAIEEYTELKTVWIDTGSRITDPFSKT"
     gene            complement(12113..12925)
                     /locus_tag="BKM31_RS14370"
                     /old_locus_tag="BKM31_14235"
     CDS             complement(12113..12925)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="BKM31_RS14370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14235"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_186403938.1"
                     /transl_table=11
                     /translation="MSDSSLDLHGPLALGGKTFIVTGGGSGIGLCTVEHLLAAGSSVVA
                     VDVNTDAVKSVDGDVTVVCGDVSLPEVAAEAFELAMVSGRLDGVVFAAGTSSTGSMAEL
                     SMEVFGQDLARNLSVHLPLSQAVLRHRSAHRTDTQCSLVYVASKHAVAPSTGFGGYPVA
                     KGAVLQLARLFALEGAKLGIRANTINPGAVFDGSKFWEETLSAEKAQSHGVSVDELPDF
                     YARRTLLGVRVTPADVANAIMFLLSPLSRATTGAIIGVDGGLPVSFAR"
     misc_feature    complement(12818..12820)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(13046..13059)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.61"
                     /tool="antismash"
     misc_feature    13049..13062
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.04"
                     /tool="antismash"
     misc_feature    complement(13053..13068)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.91"
                     /tool="antismash"
     gene            13205..14014
                     /locus_tag="BKM31_RS14375"
                     /old_locus_tag="BKM31_14240"
     CDS             13205..14014
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS14375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_14240"
                     /product="hypothetical protein"
                     /protein_id="WP_155127116.1"
                     /transl_table=11
                     /translation="MNAERATPDLLDGLLKERCGSSVAELVEDVRLNGDETFFWSGSWV
                     EGFANSRSDLDLYLISPDPGRTSGVPQVTGPGMPPMYMTLTPGRTKIDLTVVPVELLVK
                     LNGFLTAFNGETDYPTAWSDNFREFVHRLSIGVPLANAERFDEIQRGVDFMKFRQYLMR
                     FYQNRADGLFDDAQGLLDEGDVVSAYFVARQRVEAAIDMYLAANGETNTRVDKWRWKKL
                     KRLLADDTSLADRFLDCEAIGGTVHGDTLALTQRCLQFGDEIILKAI"
     gene            14029..14577
                     /locus_tag="BKM31_RS14380"
                     /old_locus_tag="BKM31_14245"
     CDS             14029..14577
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045184.1"
                     /locus_tag="BKM31_RS14380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14245"
                     /product="DUF6817 domain-containing protein"
                     /protein_id="WP_080038623.1"
                     /transl_table=11
                     /translation="MTNIDRNAVVQFLEERGTARIKLHHRSLLDHLVGTEQLLRSWGCP
                     DDVAIAGLCHAVYGTDGLVAPLVELADRPKLSALIGDAAESAVHLYGCCDRKFVYPQLG
                     NGAEVTWRDRFTGREWVVDAAELATFTLLTWANALEAAGAGTDGDWSAVSYLFLLTADL
                     VGPQPKQAATEILGVDFAA"
     gene            complement(14622..15347)
                     /locus_tag="BKM31_RS14385"
                     /old_locus_tag="BKM31_14250"
     CDS             complement(14622..15347)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /locus_tag="BKM31_RS14385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14250"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_155127122.1"
                     /sec_met_domain="Abi (E-value: 1.3e-05, bitscore: 24.9,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVALPAAVTLGAIVFWVAQMPAAATVLAAVATVWAMQLIAPAV
                     RRRSLSMDGWASELLFASPFVLFFLPYVAWTVAARPPLTWDWAGAALAVTTAVAVYASN
                     WRQLRVGFDREFLEIMPPLHLTTAALRSYQLQAAAIGQELFYRGVVFEFLRPTIGWAVI
                     VVSTVLFVVEHLGNRWAGAVLDRAYVVRITVLSTALATIMFVTGSLWAALLGHVVYNLF
                     PVAQVAWRYHVNPYRRGEP"
     gene            complement(15424..16098)
                     /locus_tag="BKM31_RS59600"
                     /old_locus_tag="BKM31_14255"
     CDS             complement(15424..16098)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS59600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_14255"
                     /product="hypothetical protein"
                     /protein_id="WP_155127125.1"
                     /transl_table=11
                     /translation="MDSISNGFLAVLLGPDGAGKTTLTTRMKSLAPEWRFTSLQPEDLY
                     PIERLECYNWALQTHPREYVQHMAPMVRTSYFLHIIALEWEYHIRPALAENRIVLSDSY
                     WYRPAAKEFIHNPSSSSILDGLADLLPEPDLIVWLDVPLEEAWRRNGPPTVFEVAGDDT
                     TYPAFADFQQRVLEDLHDQVKGIPQMVLDGTMAADELARSAVDGIRTIAESRGTRAADD
                     RK"
     misc_feature    complement(15928..15930)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16120..16410)
                     /locus_tag="BKM31_RS14390"
     CDS             complement(16120..16410)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="BKM31_RS14390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_186403939.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.6e-10,
                     bitscore: 39.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 7.4e-12, bitscore:
                     44.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.6e-17, bitscore: 61.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.5e-06,
                     bitscore: 27.9, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGEVLDTAARPRRQDGTRVRRVGGRVVLILESGGLELNQTAESV
                     WMLCTGTASVADIVKQITEEYDADEEDIRADVVELLEELESLGALEIVAPA"
     aSDomain        complement(16147..16347)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BKM31_RS14390_PqqD_RRE.1"
                     /evalue="1.70E-14"
                     /identifier="RREFam006.1"
                     /label="BKM31_RS14390"
                     /locus_tag="BKM31_RS14390"
                     /protein_end="88"
                     /protein_start="21"
                     /score="44.3"
                     /tool="antismash"
                     /translation="RVGGRVVLILESGGLELNQTAESVWMLCTGTASVADIVKQITEEY
                     DADEEDIRADVVELLEELESLG"
     aSDomain        complement(16156..16365)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BKM31_RS14390_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="6.00E-13"
                     /identifier="RREFam002.1"
                     /label="BKM31_RS14390"
                     /locus_tag="BKM31_RS14390"
                     /protein_end="85"
                     /protein_start="15"
                     /score="39.6"
                     /tool="antismash"
                     /translation="DGTRVRRVGGRVVLILESGGLELNQTAESVWMLCTGTASVADIVK
                     QITEEYDADEEDIRADVVELLEELE"
     aSDomain        complement(16159..16308)
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BKM31_RS14390_Subtilosin_rSAM_RRE.1"
                     /evalue="3.50E-09"
                     /identifier="RREFam018.1"
                     /label="BKM31_RS14390"
                     /locus_tag="BKM31_RS14390"
                     /protein_end="84"
                     /protein_start="34"
                     /score="27.9"
                     /tool="antismash"
                     /translation="GLELNQTAESVWMLCTGTASVADIVKQITEEYDADEEDIRADVVE
                     LLEEL"
     misc_feature    complement(16490..16505)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.82"
                     /tool="antismash"
     misc_feature    16648..16663
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.77"
                     /tool="antismash"
     misc_feature    complement(17269..17283)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.27"
                     /tool="antismash"
     gene            complement(17893..18450)
                     /locus_tag="BKM31_RS14405"
                     /old_locus_tag="BKM31_14265"
     CDS             complement(17893..18450)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS14405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_14265"
                     /product="hypothetical protein"
                     /protein_id="WP_080038628.1"
                     /transl_table=11
                     /translation="MKILRNAFLGTMAVAATMTVSTAAHAEPAPVPTSQVIEPAVKAAK
                     PERPVGKPKIQSELPVRALNADGNFYVWSDDMNKALLYSGDASFDGWPDGWNNTVDVVW
                     NNGYPGPYDDVNIYDYAIWSGSAYACIGNGDYWDLRRRDVNYVFSWVNDGADAWQRSPL
                     GRRVHDNGSGHVWVDWCGNNNR"
     gene            complement(18447..19247)
                     /locus_tag="BKM31_RS14410"
                     /old_locus_tag="BKM31_14270"
     CDS             complement(18447..19247)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS14410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_14270"
                     /product="hypothetical protein"
                     /protein_id="WP_080038629.1"
                     /transl_table=11
                     /translation="METGILHQAEQVLIGACMSGRNLRYWPEPESRTPDMDRFPYVVDD
                     EEWARENGYGRAARKELERAAAPSRDYFHGLPEERRRAWLTAYHGDRAAVIEAELPVGG
                     TVGHSANGCVAQAWQELYGDKARWFRASRVTRTLIQMRVGRTQAAPAYVAARQRWSACM
                     KAAGITADTPLALRRQRLADQEAGAEARDRLVATAEARCAGSSGLSRTARDLDAANASA
                     LEAQYPAEYRNARDLREAALPRARALIRKTLTNQNSPDKEEPSS"
     gene            19499..20503
                     /locus_tag="BKM31_RS14415"
                     /old_locus_tag="BKM31_14275"
     CDS             19499..20503
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024248.4"
                     /locus_tag="BKM31_RS14415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14275"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_186403940.1"
                     /transl_table=11
                     /translation="MHRIHFTSDDLARVRVAATLGPMAETLFSLTALRGRSGEATFGAW
                     RRRARAGLDSRYAVLGAVLPPGGPSFDLANLAGPGRDFAESAENFLARSRHAVRAELDY
                     YADHHGRVPAALAALVDSPAARRELLSRVESYHQAAVEPHWNRIQAHLAAERTRRGTIM
                     LDQGVDGLLSTLHPDIRWAPPTLYIRNGDETPAELTLDGRGLLLVSSFFLRVPTVMYDP
                     RSLTGGFLFYPAALGAEQAASVWTTGTSSSALAGLLGRTRAAILTAIADGVTGTGVLAR
                     RLDVSSAAVSQHTAVLREAGLITTLRHHGTVQHHPTPTGLALLDRPDTPHAGP"
     gene            20673..20942
                     /locus_tag="BKM31_RS14420"
                     /old_locus_tag="BKM31_14280"
     CDS             20673..20942
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS14420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_14280"
                     /product="hypothetical protein"
                     /protein_id="WP_080038631.1"
                     /transl_table=11
                     /translation="MLLGSGEHPYRAPLPFSDQYTLPRTIAVPSARTGLCLDSRLFTML
                     LAAARRPAIEKLLRRPRTRELLLTALTRIHLGGGGFAVTVGAGR"
     gene            complement(20992..21942)
                     /locus_tag="BKM31_RS14425"
                     /old_locus_tag="BKM31_14285"
     CDS             complement(20992..21942)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="BKM31_RS14425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14285"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_155127128.1"
                     /transl_table=11
                     /translation="MARSLYARMRDRGESLPEAAEELRLAAADIDRARSQLVRLQLLNP
                     ETQTAADVATALNRSLQSSHRLLDSVIEQHVKTASLAKHYLGLSGPADSHAHVEFFPWP
                     DRREHLSERIDELAEQAEHEVLGMHPIAPWTRESLEAGLARSETTARNGVRLRALHAQI
                     AMSNPLIREFMGEWRRCGIEVRVTPVIPTRMLIYDRHTAVVQADPESLQAGTVLIRGGG
                     VVKSLAAIYDYCWTTASEPEDVPRSTDGVSLTEQQLAVLRMLAAGAKDSAIARSMGVST
                     RTITRLVGELTAVLGASSRFQAGVRAARLGWLDPG"
     gene            22164..22397
                     /locus_tag="BKM31_RS14430"
                     /old_locus_tag="BKM31_14290"
     CDS             22164..22397
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850483.1"
                     /locus_tag="BKM31_RS14430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14290"
                     /product="heavy metal-associated domain-containing protein"
                     /protein_id="WP_080038633.1"
                     /transl_table=11
                     /translation="MITVAYSLVAYRIAGLSPETCGHCLAAIKSELIQVPGVVGVEVDP
                     AEGRVSVLTDGPVGEEQVRVAVEAAGCAVADS"
     misc_feature    22459..22472
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     misc_feature    22681..22696
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     misc_feature    22681..22697
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 25.37"
                     /tool="antismash"
     gene            22733..23857
                     /locus_tag="BKM31_RS14435"
                     /old_locus_tag="BKM31_14295"
     CDS             22733..23857
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017587414.1"
                     /locus_tag="BKM31_RS14435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14295"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_080038634.1"
                     /transl_table=11
                     /translation="MSDAFARPGEPQVEGFVADGYDKVREVFQKLVHDGRETGAGVSVW
                     RDAREVVRLSGGWADSSRRRPWSADTLVQPYSLSKSFVTLAALVAVRDGSLALDEPVAR
                     YWPEYGVRGKDRTTLRHVLTHRAGQPRFPAEAAGLDLLDDAGLRESLAQAAPEYVPGTS
                     LGEHALTYGHLVDGILRAGAGTTLGETFNEVVRPALDLDAWFGVPDDQLGRVADLEYAD
                     PDWPHRLHAAPWLQIPDGTLDVERANSRAWRQTVFGAVNLHTTATAMARFFAELTAEDG
                     PVRTLLGPELHAELLAPQVTDFDEVFGTRITWTLGFVRDHGKIAKGGIGGSAAWWSRRH
                     HHGCAYLTRRLDDHSRAAEIAAALGDDLTVVGED"
     gene            complement(24218..25153)
                     /locus_tag="BKM31_RS14440"
                     /old_locus_tag="BKM31_14300"
     CDS             complement(24218..25153)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620471.1"
                     /locus_tag="BKM31_RS14440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14300"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_080038635.1"
                     /transl_table=11
                     /translation="MHRVVALVRPVQSTFELGCAAEVFGTVRDGLPQRYEFEVCAERPG
                     PVPTTAGYAMSVPRGLSALATADTVIIPGWAPVEAPLPPRVRRALLRAHARGARLVTIC
                     SGVFALARTGLLDGRSATTHWARAARLRREFPQVRVEPDKLYVDHGDVATSAGAGAGID
                     LCLHLVRRDHGAAYAALLARHMVMPPHRDGGQTQYIPSAPPDDSLDGLLAWAAARLATP
                     LSVGDLAAYLNVSPRTLARRFADHLGTSPGAWLLSRRIAEARTLLEETDLPVEAIATRV
                     GLTSAVNLRRHFHTRVGTTPGAYRRAFRIS"
     misc_feature    complement(25163..25179)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     gene            25225..25560
                     /locus_tag="BKM31_RS14445"
                     /old_locus_tag="BKM31_14305"
     CDS             25225..25560
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620470.1"
                     /locus_tag="BKM31_RS14445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_14305"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_080038636.1"
                     /transl_table=11
                     /translation="MYPEILAQEGYTSVSVDEAPVREVFPGIRLRPLWKGPTGAHAHVL
                     EMDPGTSWPRRDVHEPGPEEVYVVAGTFSDGARDYPAGTFLHAPAGTWHVPSSATGCTL
                     FLFYPEG"
ORIGIN
        1 gcctgggcgg accggtcggc tccggcaaga ccgccaccgt cgccgccctg tgccgcaccc
       61 tgcgcgctga gctgtccatc gccgtcgtca ccaacgacat ctacacccgc gaagacgccg
      121 aattcctgct gcgccaggcc gtcctgcccg ccgaccgcat caccgccgta cagaccggcg
      181 cctgcccgca caccgccatc cgggacgaca tctccgccaa cctcgaagcc gtcgaagatt
      241 tgcaggacca cctcggaccc ctcgacctca tcctcatcga atccggcggc gacaacctca
      301 ccgccacctt ctccaagggc ctcgtcgacg cgcagatctt cgtcatcgac gtcgccggcg
      361 gcgacgacat cccccgcaag ggcggccccg gcgtcaccac cagcgacctg ctcgtcatca
      421 acaagaccga cctcgccccg cacgtcggcg ccgacctgga ggccatggcc cgcgacgcca
      481 aagcccagcg cggtgacctg cccaccgtgc tgaccgcggt caaaaccgca ggcggtatca
      541 cccctgtggc cgactggatc cgcgagcggc tcgccgcctg gaccgcgggc cccgcatgag
      601 gatcgcggcc gcttcgcccc cacccgcgca gggcgcccca gcgcagccca caccggcccc
      661 ggccgtgccg gttgagcccg ggcccggcgt gcgcgccacc gcccgcatcc gcgccgcccg
      721 tgccggcgac accaccgtct tgcccgtgct ggccggtgac ggccccttcg acctgcgccg
      781 cacccgcccg caggggaacc gggcccgggt gtgcatcctc ggcgtgatga gcgcacccct
      841 cggcggcgac cggctgcgca tcgaggccac cgccgaaccc ggcgcccacc tgcacatcac
      901 caccgccgcc gccaccatcg cgctacgcgg ccccaccacc gcccacgcca cctacgacgt
      961 gcacctgcgc gtggccgaac aggcgagcct gcactggctg cccgagccgc tgatctccgc
     1021 cgcccgcagc aacctgcgcc agagctgcac catcgacctc gccgccgacg cccgtctcgt
     1081 cctgcgcgaa gaactggtcc tcggccgctc cggcgaacca ccgggccggc tgaccacccg
     1141 cctcaccgtc caccgcgacg gacggccgct gctggaccag cagaacacct acgggccgga
     1201 cgcgcccggc tgggacggcc ccgccgtcct ggacggccac cgcgccgccg gccagctcct
     1261 catcgtcgac ccggcctacg acaaggagcc gcccgccgtc cggctgttcg gcgacgaccc
     1321 cgcgggcggg caggccgtgc tgaccccgct cgccggacct gccgtcctga tcaccgcgct
     1381 cgccccgaac accctgcggc tacgccacct cctcgatgca gccgaccccc tcggccgatg
     1441 agctgcggcc ggcctcccgg aaggtctcgg agatgcggtt cttgcgggag tcggagcgca
     1501 ggcgccgcat cagcgtggcc gaggacaggc ggccctcgct gatggagatc gccacccgca
     1561 tcaggtcgaa cccgaacaag gtggccaggg cgaagaccgg ggagttctgg ccctgcattc
     1621 gccagcagcc cttcgatcag gtgcaccgac tcccaccccc ccgcacggga tgaaccgggc
     1681 gaacagcgcc acgtaggtgt cggagacgta ggggccgacg tggcgatacc agctcagcca
     1741 gtgggcggta cgcgccacga tcggcagcag cgaccgctcg ggcatgcgtc gctcgatctc
     1801 ggccgccaga cgctcggcgt cggcatggct gcccctggcg cggcggcgct tgagggtggg
     1861 cacaccaccc tcgtcgatga ccagatcggc gttgccgagg tagccggcgt ccagatgcgc
     1921 ggccgcgctc aggtgggcgt ccttgaggtg agcgacgaaa ccggcggggg tgtgactcct
     1981 ggggtggggt ggggtcgatt cctgagggac gggaccaacg ttccggtcgg ctcgggtgtc
     2041 cgcaagggaa tcggtgtcgt ccgcctgtcc ggcgtgcgtt attacgcgtg tacgcgcagg
     2101 tcggcatagg tgttcacgcg aggcccggcg caccggccag gaaccccttg cgaagccttt
     2161 atagatccat ctagcatgac cgaatgtccg cattcaacac gagtggtggg tgaaagtcag
     2221 agcgcacctg acaacgtcgg gcgaatagtc cccggcgcat gatgagcgca tttgtgcgcg
     2281 cgcgtggatt cagccgcctc gggccgtgag agataggaac acacgtgcat tcttcagtgg
     2341 ccgcctgcga gttccctggc cggtgcggat gacgtcgtcg cccatggaac aacagaaagg
     2401 atggcggacc cggctgctcg agtccgtgga gctgcagacg ggtcctcggc gggtcctggc
     2461 gatctcgacg ctggtgaaca ccacgggcag cgggctgttc ctcacggccg gggccctgta
     2521 cttcacccgc gtcgtcggat tgtccgtggt ggaggtgggc gcggggctca cgatcgccgg
     2581 tttcgccgcg ctcgccgccg ggatcccggt gggcaggatg gccgaccggt gggggcctcg
     2641 ccggctgtgg gcgatgttcc tggtgctcga agcctgcgcc atggcgggct tcctcttcgt
     2701 gaactccttc ccgtccttcg tggtcatggc ctgcgcgagc cagttcgcgg cggcggccag
     2761 ccagaccgcg cgcatgccgg tgttccgccg catcggcggc gccggcgcga cccggctgcg
     2821 tgccgtgatc cggtccctgg tcaatgtcgg cacgagtctc ggtgctctgg cggccggcgt
     2881 cgtcatcacc atcgacaccc gcttcgccta caccgtcctc atcctcgcca acgcgatcag
     2941 tttcgcggtg aacgtgttcc tggtcctgct tttgcccaag ctggatccgc tgcgcgccaa
     3001 gtcggagagc acgacgggcg tggcgctgcg cgaccggcct ttcctggcga tcaccgtgct
     3061 gaatggcatc ctggcgttgc aggggcctgt gctcacgttc gcgataccgc tgtggatcgt
     3121 gcagaacacg gcggcaccac ggtcgatatt cgcgattctg gtcaccatca acacggtgct
     3181 ggtcgcgctt tttcagctca gcgcgacaaa aggcatcgac aacgtgataa aggcgggcgg
     3241 cgcggcccgt accgcgagta tcggcctttt cctggcgttc tttctcttcg gctgggcgtc
     3301 agggttcagc gcgaccgtcg cgaccgttct gctcatcgtc ggagtagtcg tgctgacctt
     3361 ggcggagctg cgttatgcgg ctgccgagtt cgaattgagc ttcgggttgg cgcccgctca
     3421 gctgcagggc gaatacagcg gggtcttcgg gctcgggcag ggtctggccg cctcggccgg
     3481 gccgtacctg ctcgcggtgc tcgtgctagg aggagccggc atcaccggct ggatcgtcct
     3541 cggcgtgctg atggtggcgg cgggactgct ggttccggcg gctgtggcgt gggcggagcg
     3601 gacccgttcc catgagccgg aggcgggctc ggaagccaag gcctgatgcc ggtgaggccg
     3661 ccgtggccga gtgcgaggtg ctcggccacg gcggcctcac cgctttcacg ttccgccggt
     3721 caccacgtga ccggcaggcg ctggacgccg tagatgaccg cggcctgcct cgtcggcacc
     3781 tcctcgggag gaagggcgag gcgtaggccg gggaaccgtt cgaacaatgc agggaacgcc
     3841 agccgcatct cggcgcgggc gagctgctgg ccgaggcact ggtggatgcc gtggccgaag
     3901 gcgaggtggc ccatgttccg ctttcccgcc ctggcgtacc gcgtgatgtc caggctgtcc
     3961 gggtcgtcga aacacgcggg atcccggttg gccgccgcca gggacatgca gaccacctgg
     4021 cccttcttga tggtgacccc ttcgatgtcc acgtcctcca gggccgcccg catcgggccg
     4081 atgtgaatga tggtgaggta gcgcagcagc tcctcgaccg tgctgtcgat cagtgagggg
     4141 tcctgacgca gcgccgcgac ctgggcggga tgctcgagca gggcgaaggt gccgagcccc
     4201 agcatgttgg ccgtggtctc gaagccggcg ccgaacagca tgaagccgat gttggtgagc
     4261 tcctcatcgg tgaggtcgct gttgttgatc aggtcgctgt agaagtcgtc cgtcggcctg
     4321 gcccgcttgc tggcgatcag cggcgggaag aggctctgca tggtgatgaa cgcctcgatg
     4381 aggtcggcct gcttggtgtt caggtcgacg gcgacgccca tcgcccgctg gaactccgct
     4441 cgctcgctct ccgggatgcc cagcaggtcg cagatgaccg ccgacgggat gggaaccgcg
     4501 aactcctcga ccaggtcgac gggcgggccc gaacgttcca tggcgtccag gcagcttcgc
     4561 accactgcgc tgatcttcgg ttcgagctgt ctgatccggt gaacggtgaa ctgggcgatg
     4621 aggagccggc ggtagcgggt gtgctcgggc gggtccatgc ggatgaacat gcccggctcg
     4681 gacggctgcc gcttcttgga gatgtcccga tcgacgggca ggtgcatgag ctcgcgccgg
     4741 ttgctgaacc ggtcgtccgc gaggatcttc cgcacgatgc gatgactgca ggcgagccag
     4801 ccctcgtgcc cgtcggcgaa cgtcatcggg gtgagcggat gctgctcgcg gatgctggcg
     4861 aacacgtccg gcgggtcgaa gggcccaggt ctcttgccgg tcggaaaggt gaacgcggtt
     4921 tctgtcactg tgtcttcctc gaagcgtgga gcctggtctt cctcgaagcg tggagcctgc
     4981 ccgtccgtga cagccggctc tcaggtcgtg ccggtcagca ggggaaggtc tctggggacc
     5041 cggacggcgg gtttcgggct cggcagccgc cgccggttga ggaccggcag ggcgaggtag
     5101 ctgtcgccgt cgcggacgac gaggcccgcc ttgagcagcc gctccagagc acccgcgatc
     5161 tccgtggcgg gcacgggcac gggcagggcc cgctcgatcg cctgcgcgga ccggagctgg
     5221 tcgagcgcga gcaggacagc gctggccgcc gggtcgaggt cgaactcggt ctcggggcgg
     5281 ggccgggcgg gccgggtgtc gatgacgcga aggtggtcgt ccgtccagga cgcttcgagc
     5341 cgcgcctcgg cgtggtcctg tcgccagcgc tccgcggcgg ccgacatcgc ggccagcacc
     5401 ggctcggagg cgaggggttc gtcgcaacgc atgcggaaga agtaggcgat gtcccggcgt
     5461 tcggcgctcg gcaggtcggc gtacacgtgg tcgtaggcgc gctcgtgcgt cagctcgacg
     5521 atcccgaagt ccgcgcccga ctcgtagaag gggctgaagc gatccgcgcg ggccgggccg
     5581 acgtgttccg gcggcgacag gtgggggacg aggctgaaca gctgcggcag gtccgcgtag
     5641 tcgtcgtcgg tctcgcccgg gaagccgtgc agatagttcc acgacacgtc gatgccgagc
     5701 tcggcgcacc acttcatcgt ctgcaggttc cgcagcctgg tggtcccctt gcgcatggcc
     5761 tccaggagcc ggttgctcat cgactcgatg ccgggctgca ggtggtggac gcccgcgtcg
     5821 cgcagcagca tgagctggtc gaggcggagg ttggacttca cctcgtagtg cagggagacc
     5881 ttcaggtccg actgcgcgat catcggcagc aggtcgttga aatagcggta gtcgaggatg
     5941 ttgtccacga ccagcacgtt cgtccggcgc ttcgggcccg gcccgtagtc gtggaccagc
     6001 ttgcgcagct cgtcgaaggc tctcgcggcc gacttgctcc tgaacgccat cgtcatgccg
     6061 ttcaggccgc agaacgtgca gtgcttcttc tcgccccacc agcagccccg cgaggtctcc
     6121 agggggacgg cggtgtcgac cggcaggctg ctgccgggcc cggaggcccg cagccgggtg
     6181 tagaagtcgt ggtattccgg caccggcagg tcgtccatgc tgggggcggt gccggccacg
     6241 atgacggccc ggcccccggg ctgcggctcc gccctggcgc tccagaacgg gtccgcttcg
     6301 atccagccgg gacggccgcc cgcggcgcgg aagtcgctca cgaaccggct gatcaaccac
     6361 tcggcctcgc cgcggaacac gtagtcgatc gcggggtagt tcctcaggat cgccgagccc
     6421 atcggcccct cgcagttgcc gccgcccatg atgacggtga tgtgcgggtg cagctgcttc
     6481 agccggcggg cgaacccgag ggcggcgacg ttctgctgga aggtcgacgt cagcccgacg
     6541 aggtcgtagc gttcccagac ctcgtggcgc gccagggcgt ccaggaacgg cgccgtcaac
     6601 gccttgatct cacccagctg gaagatcgtg gcgaagtcgg cgaaccctcc gtgctcgtcg
     6661 agcaggacct cgttcaggaa ccgctcgccg ccgtccgcgc cctcgaccga gccctccgtg
     6721 aacaaccact cgccgaccag ggccaccttg ggggaggagg tgccgatgcg gttgtacatc
     6781 gtgttgccga cggcttcggc gaagtccagg ttggcgtaga tgacgtcgct ggcgatgctg
     6841 ctcgcggtga gggcggactg cagcagggag accccgatcg acgcccagcg ggtctccgcc
     6901 cacggcatca ccacgaaggc cacgcgtggc gacgcggtgc cgtcctgccc ggtgctgccc
     6961 tgcccggtgc tgtcctgcgc tgtggggttc gccgcggcga tgtcgaggct catcgtcgcg
     7021 ctccggccca ggcgcgctcc acctccccgg gcgaagaacc cttcgatctc ctcgcgcagc
     7081 gatccgccga gcgcgctcgc cggatcgatt tcggcggcac gcaaggccgc cgacacgtcc
     7141 tcccggagcg cttcgcgaaa tgccgggtcg ataaacgtac gggtcagcag cgcgcgctgt
     7201 tcgccggaga actcgctgga gactcccata ggctctcccc ttccatcggt gacaccggga
     7261 ggcatggcgg attccaagat tgtaagcgag aaaggccggt gtgcaaccaa tgcggcagat
     7321 gaatgtgaat gatgtgcccc ggtccattgt tggaacgcgt caataggggc tcccgattga
     7381 cccgtcaggc aaagagcggg ctcttgactg cgccgggtaa ggaagtcagg ggcggtagtt
     7441 cacggaacgt attcatccgg ccgacgtgac aagagtgctt gacgaggcgt cggggatcga
     7501 cctacgatca tttcggccta gatcaacgag agaaaggaat ggccgtgaag aagcgttacg
     7561 tgaagcccgt cgtgcgtcac atcgacctcc tgggtgctgt gatcatcgac taagttcctc
     7621 gacaggtatg tcgttaaagg aagaacaggc ggtccattca gtgtccactc gtgagggaag
     7681 catcttgagt gagatctgcc tcagtgaagc cgaccggcgc gagctcgctg aagtggcgtc
     7741 ggtcgtggtg gggtggtcac tggatggtcc gtccatagaa gccctgcgcg agcgggccgg
     7801 ccagtccgag tcgctccggt ccatcgggct ggacgtgcgg cgcaggatgc gcgaggacgg
     7861 cttcgccctg gtcaagaacg tcccgtgcag cgaggacgcc gagctcgtcg cctttctcgg
     7921 cctcatcgcc atcccctctg ctccgggcaa cggcgatacc ctcttcttcg acatctcgcc
     7981 gagttcgtcg cgctcggacg acgtgtcggg caccagcgcc gagtttccgc tgcacaccga
     8041 ttccacattc ttctccgtcc cccatgacgt gctcgccctg gcgtgcgtgc gaaacagtga
     8101 ctcgggcggc gagtccatca ttgtgcgcgc ggcggacgtg gcggatcggg tacgcgccat
     8161 aggcggcgcc gacgcactgg cggcactcgg cgaccaggtt tatccgtttt acctgcgcga
     8221 cccgctgttc ggtcacggaa ttcagctggt gcccatcctg gtcgcggacg gcgacgaatg
     8281 gtgcatccgc taccgcggcg atattctggc gaagctgacc gagcggttcg aactcgacga
     8341 ggtccaccgg cacgcacttt ccgtgctcaa ccaggtggtc gccgagcccg aatcgggcgc
     8401 ggtgcaggtg cggctggaga cggacgacct catcatcgtc gacaatcgcc gggcgctgca
     8461 cgcgcggacg gcactcggcc ccggcgaacg gcggctccgg cgaatgaagg gctattcgct
     8521 cgacaattcg gcctggcgga tcatctgact ccgcgcgccg cccggcgccc gttatgcagg
     8581 gacgccgggc ggcgcctttt tctgcctccg tttttctgcg tccgtacgag cgcttttccc
     8641 gcgcccgtac gagccgcttc ttcagcgctg tcacggtgcg ccggcaccgc gggcctggcg
     8701 gatgtgctca cgcagcgccc ggtaccagcc gagaagcacc acgattcccc agacggtcct
     8761 ggtgttcgcc gacgggtcac ggtggaagtc gccggcgagc cgggccagcc cggcggcctc
     8821 caacccgagc tcctcggcgc cggcaccctc gtggaggaga tcgagtgtca ggtcgcgcag
     8881 cgggccggcg agccagacgg acgcgggagc ggagaacttc tgcttcggac ggtccacgat
     8941 gctcgcgggg acgagcccgc gtgccacgga ccggagcacc tccttgggtc ggcccgtcat
     9001 cagcgagcgc gcgggccgcg cgagcgccca gtccaccacg ccgtcgcgga ggaagggcac
     9061 ccgcacctcc agcccatgcg tcatggacag ctgatcgacc cgcggcaggt ggtagccggg
     9121 cagcttggcc gtgacctcga accagcggat cacctcggcc gcgtcggccc caccggccgc
     9181 tagtccggcg aatccgaacc gctcctggga gacgtcgggg gcgcaccgct tgagcatgtc
     9241 gtcgtccagg acccggcggc gatcgtcgtc ggtccaccac ccgagcgcgt tccagtaccg
     9301 gtcgcgccag ggctcgccgc gaagcgcggc ctggtgcgcc tcgtgcatgt gcgcgtagcc
     9361 catcagcagc tcgtcagagc cgtccccggc cagcaccgcc ttgtgctgtc gggccgccag
     9421 tccgctgacg gcatgggtgc tgagacacac aggggtgtag atcggctcgt ccatcgatcg
     9481 gagcgtcgcc aggaaggtct cctgcacgtt cgactccgtg aggtgcgtga tgtcgtgccg
     9541 ggcgccgatg tgccgggcga tctcgccggc gtagccggtc tcgtcctgcc aggtgttggc
     9601 ggcgtacccg acgctgaaga cgtcgatcgt gcccctctgc tgcgcggcca gggcggagac
     9661 ggtcgccgag tcgagcccgc cgctgaggaa ggccgcggcc ggcgcgtccg gtgggagcgt
     9721 tgtcgacacc gattcccgca gctccgtggc caggcaaccc tggggctccc gcgctgcgga
     9781 gaaggcgggg aaccggagcc agcgggattc gcggaccata ccggacgggc gctgcctgtc
     9841 gaagacgacc gtggttcccg gctcgatctt gcgcacgtgg gtcaacgggc tgcacgccgg
     9901 tggtgagaac cgtacggtga agtagtctgc ggcggcgtcc cggctcacct cgacggggac
     9961 gtgcggatcc gccacgagtg agcgcagctc ggaggagaag acgagccggt cctgagccgc
    10021 gtacaggtag agcggcttga tccccatccg gtcgcggccg actgtgagag tttcccggcg
    10081 ggcgtcccag atcgcgaagg cgtacattcc gtccagccgc tcggtgaagc tctcggcgtc
    10141 acgcagatag gacgccagga tcacctcccc gtccccgcag gtcaggaacc ggtgcccggc
    10201 gctctccagg tctttcctga gccgtgcgtg gttgtagatc tcgccgttga agacgagatg
    10261 cacgccggcc gcccgatagg agatcggctg atccgatccg gcgacgtcca cgagcgacag
    10321 gcgaacggcg ccgagggcgg cgggtccgct ggacacggtt ccccggctgt cggggccgcg
    10381 gtgctcgaag gcggtcagca ggcgttcgac cgtccggaga tcagcggtgt cccggcccca
    10441 cctgacgact cctgcgatcc cgcacactgc tgcccccaaa cgcgttgctg tgaccattgc
    10501 ggtgtagttc ggatggatgg cgccggctgc cgcgaagccg cccgagcggc tccacaggag
    10561 cggcgtcagg tcttgctgaa cgggtcggtg atgcggcttc cggtgtcgat ccagaccgtc
    10621 ttcagctcgg tgtactcctc gatcgcgtgg aagccgttct cgcggccgat gccgctctcc
    10681 ttgaatcccc cgaagggcgc gacgtggttg gtgcggcggt agttgttgac ccacacggtg
    10741 ccggcacgca ggcgccggac catccggtgc gccctggcca ggtccttggt ccagacaccg
    10801 gcggccaggc cgaaacgggt gtcgttggcg atggcgacgg cctcgtcctc gtcggagaag
    10861 cggatgacga ccgcgaccgg cccgaagacc tcctcgcggg cgatgcgcat gcggttgtcg
    10921 acgtgcgtga agaccgtcgg gcggatgaag aggccgcggg cgagcgccgg gtcgtcgggg
    10981 cggtcgccgc cggtggccag ccgtgcaccg tcctgcttgg ccacgtcgat gtagtgcagg
    11041 accttgtcgt actgggcgcg gcaggccatg gtgcccatct cggtggcggg atccatgggg
    11101 tcgccgatcc tgatccgctc cgtcctggcc accagcgcgt cgcagaactc gtcgtagatg
    11161 tcggtgtgca ccaggacccg ggagccggcc atgcacagct gcccggtggc cgcgaagacg
    11221 cctccgacga cgccgttgac ggcgctgctc aggtcggcgt cggggaagac gatgttgggc
    11281 gacttgcccc cgagctcgag cgagacgcgg gcgaggcgct ccgccgcgat gccggcgatc
    11341 ttcttgccga ccgcggtgga cccggtgaag gcgatcttgt ccaccccggg gtgcgcggcc
    11401 agggccgccc cggcgtcgcc ggctccggtc accacgttga cgacgccgtc ggggaacccg
    11461 gcctcgcaga gcagcctggc caggacgagc gtcgagacgg gggtgatctc ggacggcttg
    11521 atcaccacgg tgttgccggc ggcgagcgcc ggacacagct tccagagcag gagcgtcagc
    11581 gggctgttcc agggcgtgat ggcggcgacc accccgatgg gctcgcggac cgtgaagatc
    11641 tgcatgttgg gcacgctgcc ggcgagcgtc tcgccggtgg ggctctcggc gacgccggcg
    11701 aagaagtagg cgtggttggc cagggacttg gctcgtccgc cgacctcgcg gaccagcctt
    11761 ccgttctcca gcacctgcac ccgggcgagc tcgtcggcgt tgtcaccgat gaggtcgccg
    11821 agcctgcgca gcagagcggc tcgctggagc ggggtggagg cggcccacgg gccggtctcg
    11881 aaggcccggc gtgcggcttg cacggcgtcg tcgatgtcct gctcgctcgc ggcgggcaca
    11941 cgggcccagg gctgggaggt gaacgggttg acggagtcga acgtggcctt tcctgaggcg
    12001 tcgcgccaga ccccgtccac cagcatccgg tactgctcca cgtccgccgg ggtgcggggc
    12061 tcggtcgccg cgtcggtcgc gctcatctgg ggtgtgctct cttcctggtc gcctaccgcg
    12121 cgaaactgac cggcagccct ccatcgacac cgatgatcgc gccggtggtg gctcggctga
    12181 gcggggacag cagaaacatg atcgcgttgg cgacgtccgc cggggtcact cgcacgccca
    12241 ggagggtgcg cctggcgtag aagtcgggaa gctcgtccac gctgaccccg tgggactggg
    12301 ccttctccgc cgacagggtc tcctcccaga acttcgagcc gtcgaagacc gcgccggggt
    12361 tgatggtgtt cgcccggatg cccagcttgg ccccttcgag cgcgaagagc cgggcgagct
    12421 ggagcaccgc gcccttggcg accgggtagc cgccgaagcc cgtgctgggc gccaccgcgt
    12481 gcttggaggc cacgtacacc agcgagcact gggtgtcggt ccggtgcgcg ctgcggtgcc
    12541 gcaacacggc ctgcgagagc ggcagatgca cgctcaggtt gcgggccagg tcctggccga
    12601 agacctccat actgagctcg gccatcgaac cggtcgagga cgtgccggcc gcgaacacca
    12661 cgccgtcgag ccgcccgctg accatggcca gctcgaaggc ctccgcggcg acctccggca
    12721 acgacacgtc accgcacacg accgtcacgt ctccgtcgac gctcttgacc gcgtcggtgt
    12781 tgacgtccac cgccacgacc gaggaacccg ccgcgagtaa gtgctcgacc gtgcacagac
    12841 cgatgccgga accgccgccg gtgacgatga aggtcttgcc gcccagagcg agcggaccat
    12901 ggaggtcgag acttgaatcc gacacgagcc agttcctctc gtcttcgatt cgcgatcctc
    12961 tctgaaccgc tagggaatgg acattgctgc ccagtgcggc gcacttggca gagaccatat
    13021 atgcgtgtga tcagaatgac cagacttatg ttgacaaaaa gatgtgatcc catgtgacga
    13081 aggaggcggt aagggccacg gagggtatct tgactaacgt ttgtcacaac tgcgacactg
    13141 ctccccgtac tgctgccccc tgggcgagtg gggcgatgac ttcctgcaag agcgaggacg
    13201 caccatgaat gcggaacgag cgacccccga cctcctcgac ggcctcctca aggaacgctg
    13261 cggaagtagt gtggccgaac tggtcgaaga tgtgcggctc aatggcgacg agacgttctt
    13321 ctggagcggt tcgtgggtcg agggattcgc taattcacgc tccgacctgg acctttatct
    13381 catcagtccg gatccgggcc gcaccagtgg cgtaccgcag gtcaccggcc cgggcatgcc
    13441 gccgatgtac atgacgctca cgccgggccg gaccaagata gacctcaccg tggtcccggt
    13501 cgagctgctg gtcaagctga atggcttcct cacggctttc aacggcgaga ccgattaccc
    13561 cacggcgtgg agcgacaact tccgggagtt cgtgcaccgg ctgagcatcg gggtgccgct
    13621 ggcgaacgcc gaacggttcg acgagattca gcggggcgtg gacttcatga agttccgcca
    13681 gtacctcatg cgtttctacc agaaccgggc cgacggcctg ttcgacgacg ctcaaggact
    13741 tctcgacgaa ggcgacgtcg tctcggcgta ctttgtcgcc aggcaacggg tggaagccgc
    13801 catcgacatg tatctcgccg cgaacggcga gaccaacacc cgggtcgaca aatggcggtg
    13861 gaagaagctc aagaggctgc tggccgacga cacttctctc gctgaccgct tccttgactg
    13921 cgaagccatc ggcgggacgg tccacggaga caccttggcc ctgacccagc ggtgtctcca
    13981 gttcggtgac gaaatcattc tgaaggcgat ctgaggcgtc gagcagtgat gacgaacatc
    14041 gaccgaaacg ccgtcgtgca gttcctggaa gagcggggaa ccgcgcgaat caaactgcat
    14101 catcgctcct tgctggacca cctcgtcggg accgagcaac tgctgcgcag ctggggctgc
    14161 ccggacgacg tcgccatcgc cggcctgtgc cacgccgtgt acggcaccga cggtctcgtc
    14221 gcgccgctgg tcgagctggc ggaccggccg aagctgagcg cgctcatcgg cgacgccgcg
    14281 gagtcggccg tccacctgta cggatgttgc gaccgcaagt tcgtctatcc ccagctcggc
    14341 aacggtgccg aggtgacctg gcgcgatcgc ttcaccggca gggagtgggt ggtcgacgcg
    14401 gccgagctgg ccacgttcac gctcctgacc tgggcgaacg ccctcgaagc ggcgggagcc
    14461 ggcaccgacg gggactggtc ggcggtctcc tacctgttcc tcctgacagc cgacctggta
    14521 ggcccgcagc cgaagcaggc ggcgaccgag atcctcgggg tcgacttcgc cgcctgagcc
    14581 gcgccgtgac caccaccgtg agcaccgccg tgagcaccgc atcacggctc accgcggcgg
    14641 taggggttga cgtggtagcg ccaggcgacc tgcgccaccg gaaagaggtt gtagaccacg
    14701 tgcccgagca gggccgccca caacgacccc gtcacgaaca tgatcgtggc cagcgccgtg
    14761 gacagcacgg tgatccggac gacataggcg cggtcgagca ccgcgcctgc ccagcggttg
    14821 cccaggtgct ccacgacgaa cagcaccgtc gacacgacga tcaccgccca cccgatggtg
    14881 ggcctgagga actcgaagac caccccccgg tagaacagct cctgcccgat cgccgcggcc
    14941 tgcaactggt agctgcgcag cgccgccgtg gtcaagtgca gcggcggcat gatctcgagg
    15001 aactcccgat cgaagccgac gcgcagctgc cgccagttgc tggcgtacac agccaccgcg
    15061 gtggtgacgg cgagggcggc gccggcccag tcccaggtca acggcgggcg ggcggccacg
    15121 gtccaggcca cgtagggcag gaagaacagg acgaacggcg aggcgaagag aagctccgac
    15181 gcccagccgt ccatcgacag acttcgccgc cggacggcgg gcgcgatcag ctgcatggcc
    15241 cagacggtcg ccacggcggc cagcacggtg gccgccgcgg gcatctgcgc cacccagaag
    15301 acgatcgccc cgagtgtcac ggccgccggc agcgcgacgg tgcgcatcgt gaagatcgga
    15361 ggaggcgccg aggtcgtgcg tggcggcggg tagacccggg cgaggcgtgg aggcactacc
    15421 gcctcacttc cggtcgtccg ccgcacgagt gccgcggctc tccgcgatcg tacggatgcc
    15481 gtcgaccgcg gatctggcga gctcgtcggc ggccatcgtc ccgtccaaga ccatctgtgg
    15541 aatgcctttg acttggtcgt gcaggtcctc cagaacccgc tgctggaagt ccgcgaacgc
    15601 ggggtacgtc gtgtcgtcgc cggccacctc gaacacggtg ggcgggccgt tgcgccgcca
    15661 cgcctcctcc agcgggacat cgagccagac gatcagatcc ggctccggca gcaggtccgc
    15721 gagcccatcc aggatggagg agctggacgg gttgtgaata aattccttgg ccgccggccg
    15781 gtaccagtaa gaatcgctca ggacgatacg gttctcggcc agggcggggc ggatatggta
    15841 ttcccactca agcgcgatga tatgcaggaa gtaggacgtc cgcaccatgg gcgccatatg
    15901 ctgaacatat tcgcgcgggt gcgtctgtaa tgcccagttg tagcattcca gccgctcgat
    15961 gggatacagg tcctccggct gcaacgaggt gaatcgccat tccggggcca gtgatttcat
    16021 ccgcgtggtg agcgtggtct tcccggcgcc gtcagggccg agcagtactg cgaggaagcc
    16081 attgctgatg gaatccatcg aggtcgcgac cggtctcggc tacgcgggcg cgacgatctc
    16141 tagggcaccg aggctttcca gctcttcgag gagctctacc acgtccgcac ggatgtcttc
    16201 ctcgtcggcg tcgtattcct cggttatctg cttgacgatg tcggccacgg aggcggtgcc
    16261 cgtacacagc atccagaccg attccgcggt ctgattgagc tccagcccgc cggattcaag
    16321 gatgagtact actcggccgc cgacgcgacg aacgcgcgtt ccgtcttgac ggcgcggacg
    16381 agcagcggtg tcaaggacct caccagacaa cgttggaact cccgtctcac agggctcgct
    16441 tgtaacgatt ggatgctata ccacgttctg tcaaatttgc agtggcttcg ttgatatttg
    16501 tggatgaatc ctgagtgacg tctgagtggg tgtcgcggcg ccggaagccg atggcgtgtg
    16561 aacggcggtg tcacccctaa aggcgctccg tgaatggcca gctcagaaag ggtggcagcg
    16621 aacgggtcag ctgctgggat agcgctgtca aggtgtttgt cacgttccat tcggacgtgt
    16681 ggcccggtcg gcacaaagcg gcctcgggcg gttgtgagct cgctgtcttg acccgtatcg
    16741 cctggctgga gaaatgcccc tcgtcaccgc gacgcgctcg ctcctcagcc gctgttgata
    16801 gcggagcccg ggctcggcag tgtgggcggc gggccgcgtc ggggttccgt gagcaggtgc
    16861 ggccgggggc ggctgtctgg cgccgtcgat caggtgacgc cgcgcagtgc cttctgaaca
    16921 gcggagaggg cttcctcgtc cgaggctccg gcctggtgtg ccgcggcggc caactccctc
    16981 gccgcgctct ccagacgcag ccggtcggtc gtgcccgtga cgagacatcc cacgctcccg
    17041 accgggttgc ggtgtggagg tggtcgatgc gacccggatg ttctccgagg accagttgaa
    17101 gcggctgcgg tccttcccgg acatcagccg tgaggatctg agtcggtact tcaccctggc
    17161 gtccgccggc gtcgccttca tcgacccggg ccgcggtcgc gcgtcagccg gttcaccccg
    17221 aacggggcgt cctcgtcatc cggcgacggc gggatgtcgc gctggacttg ggccggaggg
    17281 cccgggccgc cggggagggg cgcggctcgt gcgtgacggc gagcagcggg tccggcagtc
    17341 gtgggcgcgt tttcgggcag atgcccgcgt cagggtggac cggatgtcgc agagcggatc
    17401 ctcccgtacg gcggcgggct gtcgggcatg ctctactcga tcgccgaggc ggcacctgga
    17461 gtgatcgtgg tcggcggctc cgacggcggc caccgcccag gccgaggtcg ccggggagcg
    17521 ggtggcgagc atcggcttgt cccggggcgc ggagctcgcg ctccaggtcg gcgcgctgga
    17581 ccggcgggtg gccgcggtcg tggccggcgc gccgagcagc atgcggcagg tcccacaggc
    17641 gggcggtgtg gtcccaagct cgcggtggcc gtcggggctg aaggcgacgt cgttgacgtt
    17701 gtggcggtgc ccggtgagca cggccagcgg ctcgggacgg tgccggtcgg cgatccgcca
    17761 cagccgggcc gtgccgtcgc gtccgccgtg gccggcaatc gtgcggggcc ggtggcgagg
    17821 cgagtgctga tccccgatga caggggcccg gaggaccgcc aggtcctccg ggcccctgat
    17881 cggcgccagc ggtcatctgt tgttgttgcc gcaccagtcg acccagacgt ggccgctgcc
    17941 gttgtcgtgc acgcgcctgc ccagcgggct gcgctgccac gcgtcggcgc cgtcgttcac
    18001 ccaggagaac acgtagttca cgtccctgcg gcgcaggtcc cagtaatcgc cgttgccgat
    18061 gcacgcgtag gcgctgcccg accagatcgc gtagtcatag atgttcacgt cgtcgtacgg
    18121 gccggggtag ccgttgttcc acaccacgtc caccgtgttg ttccagccgt ccggccagcc
    18181 gtcgaaggag gcgtcacccg agtagagcag cgccttgttc atgtcgtcgg accacacgta
    18241 gaagttgccg tcggcgttga gcgcgcgcac cggcagctct gattggatct tcggcttgcc
    18301 tacgggccgc tccggcttgg ccgccttgac ggcgggctcg atcacctggg aggtgggcac
    18361 gggagccggt tcggcgtggg ccgccgtcga gacggtcatc gtcgcggcga cggccatggt
    18421 gccgagaaag gcgttcctga gaatcttcac gatgagggtt cctctttatc tggtgagttc
    18481 tggttggtga gtgttttcct gatgagcgcg cgtgccctgg gcagcgccgc ctcgcgcagg
    18541 tcgcgggcgt tgcggtattc ggcggggtat tgcgcctcca gggcggaggc gttggccgcg
    18601 tcgagatcgc gagcggttcg tgacaatccg gaggagcccg cgcagcgggc ttccgccgtc
    18661 gcgaccagcc ggtcacgggc ctccgcgccg gcctcctggt cggccaggcg ctgcctgcgc
    18721 agggccagag gtgtgtccgc cgtgatcccg gccgctttca tgcaggcgga ccagcgttga
    18781 cgggcggcca cgtaggcggg ggcggcctgg gtccggccga cgcgcatctg gatgagcgtc
    18841 cgggtgaccc tgctggcgcg gaaccagcgc gccttgtccc cgtagagctc ctgccacgcc
    18901 tgggccacac agccgttggc actgtggccg accgtgccgc cgacgggcag ttccgcctcg
    18961 atgaccgcgg cacggtcgcc gtgataagcg gtcagccagg cgcgccgtcg ttcctccggc
    19021 aggccgtgga agtagtcccg cgaaggggcg gcggcccttt ccagctcctt tctcgccgct
    19081 ctgccgtacc cgttctcccg cgcccattcc tcgtcgtcga cgacataggg aaaccgatcc
    19141 atgtccggcg tcctgctttc gggctccggc cagtaccgca gattccgccc gctcatgcag
    19201 gcgccgatga gaacctgctc ggcttgatgg agaatgccgg tttccacggg cgccgccgca
    19261 catccgcaaa gcacggccag cccaaccagg gcatgcctca actgtcgtcc tgacacgtga
    19321 atccccccga gggtgacggg cctgaggccg aatcgggccg tcttccgcgg aaagccggcc
    19381 cactcactgt cgcaggaaga attcaggcgt tgtgagactt gtaagtcgtg gcttaatcgc
    19441 gccgttcagg gacatgcgcg accggtctgc ggcggggcgg cgtacacgtg gggggcggat
    19501 gcaccggatc catttcacga gcgacgacct ggcacgcgtc cgggtggcgg cgacgttggg
    19561 cccgatggcc gagacgctgt tcagcctgac cgcgctgcgg gggcggtcgg gggaggcgac
    19621 gttcggcgcg tggcggcgcc gggcccgcgc cgggctggat tccagatacg cggtcctggg
    19681 ggccgtcctg cccccaggag gacccagttt cgacctggcc aacctggccg ggcccggacg
    19741 cgacttcgcc gagagcgccg agaacttcct ggccaggagc cggcacgcgg tgcgggcgga
    19801 gctcgactac tacgccgacc atcacggccg ggtgccggcg gcgctggccg cgctcgtcga
    19861 cagcccggcc gcccgccggg agctgctgtc cagggtggag agctaccatc aggccgctgt
    19921 cgagccccac tggaaccgca tccaggcaca cctcgccgcc gaacgcaccc ggcgtggcac
    19981 gatcatgctc gaccagggcg tcgatggtct gctgtccacc ctgcatccgg acatccgctg
    20041 ggcgccgccg acgctctaca tccgcaacgg cgacgagacc cctgccgagc tgacgctcga
    20101 cgggcgaggg ctgctgctgg tgtcgtcgtt cttcctgcgg gttcccacag tgatgtacga
    20161 cccgaggagc ctcaccggcg gcttcctgtt ctacccggcc gccctcggcg ccgagcaggc
    20221 cgcgagcgtc tggacgaccg ggacgtcgtc gagcgcgctg gccggccttc tgggccgcac
    20281 ccgcgcggcg atcctcaccg ccatcgccga cggcgtgacc ggcaccggcg tcctggccag
    20341 gcgtctcgac gtctcctcgg cggcggtcag ccagcacacc gccgtactgc gtgaggcggg
    20401 cctgatcacc acgctccgcc atcacggcac cgtccagcac caccccacgc cgaccggcct
    20461 ggccctcctc gaccggcctg acacacccca cgccggccct tgacgccgtc ctcggcaccg
    20521 cccgggcacg cgatgtccgg cgggagccgg acgacctcgc caccgcacac ggcacgaccg
    20581 ccgccctgag cgtcggactc gtccccggcg tcaccaacct gctggcccgc ctggtcgccg
    20641 agcggtcacc gggcagtgac ctgcgcatcg gcgtgctgct cggctcgggg gagcacccgt
    20701 accgtgcacc gcttcccttc tccgaccagt acacgctgcc ccgcacgatc gccgtgccgt
    20761 ccgcccgcac gggcctgtgc ctcgactccc gcctgttcac catgctgctg gccgccgccc
    20821 ggcggcccgc gatcgagaag ctgctgcgcc gtccccggac acgcgagctg ctgctcacgg
    20881 cgctgacgcg gatccacctt ggcggtggcg gcttcgccgt cacggtcggc gccggccggt
    20941 gacgggttcg tcctcgacgg cgatgactga atcgcgcggc aggctcgccg gtcagccggg
    21001 gtcgagccag ccgagtcgtg ccgcccgcac gcctgcctgg aaccggctgc tcgcgcccag
    21061 caccgccgtc agctcgccga ccagccgggt gatggtccgc gtcgagacgc ccatgctgcg
    21121 cgcgatggcg gagtccttcg cccccgctgc gagcatgcgc agcacggcga gctgctgctc
    21181 ggtgagcgac acgccatcgg tcgaccgtgg gacgtcctcg ggctcggagg ccgtcgtcca
    21241 gcagtagtcg tagatcgccg ccagcgactt caccacgcct ccaccgcgaa tcagcacggt
    21301 gcccgcctgc agcgactccg gatcggcctg gacgacggcg gtgtggcggt cgtagatgag
    21361 catgcgcgta gggatcacag gcgtgacccg cacctcgatg ccgcacctgc gccattcacc
    21421 catgaactcc cggatcagcg ggttcgacat ggcgatctgc gcgtgcagag cacgcaaccg
    21481 tacgccgttg cgggcggtgg tctcgctgcg ggccaggccg gcctccagcg actcgcgggt
    21541 ccacggcgcg atcggatgca tgccgagcac ttcgtgttca gcctgttcgg ccagctcgtc
    21601 aatgcgctcg gacaggtgct cgcggcggtc gggccagggg aagaactcca catgcgcgtg
    21661 gctgtccgcc ggtccggaca ggccgagata gtgcttcgcc agcgaagccg tcttgacgtg
    21721 ctgctcgatc acgctgtcga gcagccggtg gctgctctgc aggctccggt tgagcgcggt
    21781 ggcgacgtcg gcagcggtct gcgtctcagg attcagcagc tggagccgga cgagctggga
    21841 gcgagcccgg tcgatgtccg ccgccgccag gcgcagctcc tcggcggcct cgggcaacga
    21901 ctctcctcgg tcccgcatgc gggcgtacaa ggaacgcgcc acgctgtcat ccgcagcaag
    21961 cggccccccg tccaccaccg aactccctcc ctagcgccgg ctcaacgctg aacagtggca
    22021 cattcggccc tttgtggcaa aggttccggt tttcgccatg tcgtgtttcg gaagcgtctg
    22081 atgcctccac gccggtgctt ccgtgcagca cgatctgttc tgacgcggcg cagtactcgc
    22141 cgtgaagcag aaggagggat ccgatgatca ctgttgccta cagcctcgtc gcttatcgca
    22201 tcgccggcct gtccccggag acctgcggcc actgtctggc cgccatcaag tcggagctca
    22261 tccaggtgcc gggagtcgtc ggtgtggagg tcgatccggc tgaggggcgg gtcagcgtcc
    22321 tgactgatgg ccctgtcggc gaggaacagg tccgcgtggc ggtggaagcc gccggttgcg
    22381 ccgtcgcgga ctcctgagag ttcgggcacc ggggtccgcc ggcagcgttc tggtggaccc
    22441 cacttcagtc gcccgactct gacgcagatc agggctacgg tgacgacacg cgtgcagggt
    22501 gctgtgcaac aggacatcct ggacaggagg ggcagtgtgg gggagatggt cgccgccatg
    22561 gcgcactccc cggcgctgct ggagggctac ctgaacctgt cccgcgccac aagctgccgc
    22621 aggccctcgg cgagaaggtc tcgctcaccg atgccgacgt cgccgagctg ctggcgttgc
    22681 atacctggag ggggtatctt cgggagaagt cgacgtgtgg gaggcgtgca ggatgagtga
    22741 cgcattcgca aggcccggcg agcctcaggt cgaggggttc gtcgcggacg gatacgacaa
    22801 ggtgcgcgag gtcttccaga agctcgtcca cgacggccgg gagacagggg ccggcgtgtc
    22861 ggtctggcgc gacgcgcgtg aggtcgtccg gctgagcggg ggatgggccg acagctcgcg
    22921 gcgccgcccc tggagtgccg acacccttgt ccagccgtac tcgctgtcga agtccttcgt
    22981 gaccctcgcg gccctggtgg cggtgcgcga cggctcactg gccctcgacg agccggtggc
    23041 caggtactgg cccgagtacg gggtcagggg caaggaccgg acgacgctgc gccacgttct
    23101 cacccaccgg gccggccagc cgcgcttccc ggcggaggcg gccggcctcg acctgctgga
    23161 cgacgccggg ctgcgcgaga gcctggccca ggcggcgccc gagtacgtgc cgggaacgtc
    23221 gctcggcgag cacgcgctga cctacgggca tctggtggac ggcatcctgc gcgcgggcgc
    23281 cggcaccacg ctgggggaga cgttcaacga ggtcgtgcgg cccgcgctcg atctggacgc
    23341 gtggttcggg gtgccggacg accagctggg acgggtcgcc gacctggagt acgccgaccc
    23401 cgactggccc caccggctgc acgccgcgcc ctggctccag atcccggacg gaaccctgga
    23461 cgtcgagcgg gcgaactccc gcgcgtggcg gcagacggtc ttcggcgccg tcaacctgca
    23521 cacgaccgcc acggccatgg cccgcttctt cgccgaactg accgccgagg acggccccgt
    23581 gcgcaccctg ctcggccccg aactgcacgc cgaactgctc gccccgcagg tcacggactt
    23641 cgacgaggtc ttcggcacca ggatcacctg gacgctgggc ttcgtccgcg accacggcaa
    23701 gatcgccaag ggcggcatcg gcggctcggc ggcctggtgg tcgcgcaggc accaccatgg
    23761 ctgcgcctac ctgacccggc ggctggacga tcattccagg gccgccgaga tcgcggccgc
    23821 cctgggcgac gatttgacgg tcgtgggcga ggactgagcc ggatccgctc atcgatcggc
    23881 ggcgacaggc tcacggagag ccggtctggc ggagccggcg caagatccgg atcaggaaag
    23941 ccgccggccg gccggtcgag cgcggcctgc gttggctgca tcgagcggcg ccccggtcac
    24001 ctcctggtga atgggccggt catggcgacc gggccgctgc tcgccgtgct cctgcagctg
    24061 gtgttcaagc cctggccgtg tgggcgggcg ttcgtgccgc ctggcgtcgc ggggatggtg
    24121 gtcgtggtcg ccgtggaggt cgggctggtg accagtggcg cggtgttcaa tgcggtgccg
    24181 gccgcgtacc ggctgggcaa ccctcctgcc ggccgggtca ggagatgcgg aaggcgcggc
    24241 ggtaggcgcc tggggtggtg cctacccggg tgtggaagtg gcggcggagg ttgactgccg
    24301 aggtgaggcc gacgcgggtg gcgatcgcct ccacgggaag gtccgtctcc tccagcaggg
    24361 tgcgggcttc ggcgatgcgg cgggacagga gccaggcgcc cgggctcgtg cccaggtggt
    24421 cggcgaagcg gcgggccagg gtgcgggggg agacgttgag gtacgcggcc aggtcgccca
    24481 ccgacagcgg cgtggccagg cgcgcggcgg cccaggcgag gaggccgtcg agggaatcgt
    24541 ccggcggcgc cgacgggatg tactgggtct ggccgccgtc gcggtgcggt ggcatgacca
    24601 tgtggcgggc gaggagggcg gcgtaggcgg cgccgtggtc gcggcggacc aggtggaggc
    24661 acaggtcgat gccggcgccc gcccctgcgc tggtggcgac gtcgccgtgg tccacgtaga
    24721 gcttgtccgg ttcgacgcgg acctgcggga actcgcggcg cagccgggcg gcgcgggccc
    24781 agtgggtggt ggcggagcgg ccgtccagga ggccggtgcg ggccagggcg aagacgcccg
    24841 agcagatcgt gaccaggcgg gccccgcggg cgtgcgctcg caggagtgcg cggcgcacgc
    24901 ggggcggcag cggcgcctcc accggcgccc agccggggat gatcacggtg tcggcggtcg
    24961 cgagcgcgga gaggccgcgg gggacggaca tcgcgtatcc ggccgtcgtc ggcaccgggc
    25021 ccggcctctc cgcgcacacc tcgaactcgt agcgttgcgg caggccgtcg cggacggtgc
    25081 cgaagacctc ggcggcgcag ccgagctcga acgtcgactg caccggacgg accagcgcca
    25141 ccacccgatg catggcagaa aagtacccca tggtgtcatt gctgacgctg gcccgccctc
    25201 gggcgaacgc ggcactttgg gggcatgtat cccgagattc tggcccagga gggctacacg
    25261 tccgtgtccg tcgacgaagc cccggtccgg gaggtcttcc ccgggatccg gctgcgtccg
    25321 ctgtggaagg ggccgaccgg ggcgcacgcc cacgtgctgg agatggaccc gggcacgtca
    25381 tggccgcgcc gcgacgtcca cgaaccgggt cccgaggagg tgtacgtggt cgcgggcacc
    25441 ttcagcgacg gcgcccgcga ctaccccgcc ggcacgttcc tgcacgcccc ggccggaacg
    25501 tggcacgtgc cgtcgtcggc gaccggctgc acgctgttcc tgttctaccc cgagggctga
    25561 ggatgcccct ggggcgggcg ttgtccgggc aggaagtgat ctgggaaatg gacagttccc
    25621 gctgacaccg tcgtccccgt caagccggca ggaccgaggc gggggacggc gatgcagcag
    25681 gtgcgggaca gcgacggcgt acgcgacgcg tacgaccggt cggcggcctt ctacgaccag
    25741 gtcacccagg ccgacgacta cgaccggtgg gtggcgctgt acctggagct gttgcgcgag
    25801 cacggcgtca cccccggagg ccggctggcc gatctggggt gcggcaccgg gaagggcgct
    25861 ctgcggctgg ccgggcacgg gttcgaggtg accgggatcg acctgtcgcc gcgcatgctg
    25921 gacgtggcgc gcggcaagcg gggggccggg cgggtgcggt tcgtccaggg ggatctgcgg
    25981 tgcctgcccg aggggctggg gccgttcgag gtggcggtca cgatggggga gccgctcaac
    26041 cacctgcgcg acgaggacga gctcgcagcg gcgttcgccc aggtggcgcg ggtgctggcg
    26101 cctggcgggc tgttcctgtt cgacgtcaac acggccgggt tctaccggcg gctggccggg
    26161 gtgcggcacg tcgtcgagga cgaagggtcg ctcgtgctgc atcgcggctt cgccgcccat
    26221 gaacgggaag gcgccgaact gcgggtggat cacttccggc gcgaaggctc cgagggcggg
    26281 gacggcgcgc gctggacgcg tacccacgtg ctgtactcct gggcctattt cgcccccgcc
    26341 acggtggagc ggctgctggc cgccgccggt ctggcgcagg tggccgccta cgggctggac
    26401 gccggcgggc
//
