LOCUS       NZ_CP017717            21458 bp    DNA     circular CON 03-MAR-2024
DEFINITION  [Actinomadura] parvosata subsp. kistnae strain ATCC 55076
            chromosome, complete genome.
ACCESSION   NZ_CP017717
VERSION     NZ_CP017717.1
KEYWORDS    RefSeq.
SOURCE      [Actinomadura] parvosata subsp. kistnae
  ORGANISM  [Actinomadura] parvosata subsp. kistnae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 13047416)
  AUTHORS   Nazari,B., Forneris,C.C., Gibson,M.I., Moon,K., Schramma,K.R. and
            Setedsayamdost,M.R.
  TITLE     Nonomuraea sp. ATCC 55076 harbors the largest actinomycete
            chromosome to date and the kistamicin biosynthetic gene cluster
  JOURNAL   Medchemcomm (2017) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13047416)
  AUTHORS   Nazari,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) Chemistry, Princeton University, 20
            Washington Road, Princeton, NJ 08544, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUN-2015
            Assembly Method                   :: Celera Assembler v. Jun 2015
            Assembly Name                     :: SmrtPipe 1.87.139483
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 13:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 12,000
            CDSs (total)                      :: 11,919
            Genes (coding)                    :: 11,783
            CDSs (with protein)               :: 11,783
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 36 of 136
            Pseudo Genes (incomplete)         :: 98 of 136
            Pseudo Genes (internal stop)      :: 10 of 136
            Pseudo Genes (multiple problems)  :: 6 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:57:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2079092
            Orig. end                         :: 2100550
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017717.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21458
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="proteusin"
                     /product="RiPP-like"
                     /region_number="8"
                     /rules="(PoyD or TIGR03793)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..21458
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="proteusin"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..21458
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11458](-)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11458)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     misc_feature    122..136
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     misc_feature    complement(204..218)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(284..760)
                     /locus_tag="BKM31_RS61165"
                     /old_locus_tag="BKM31_09280"
     CDS             complement(284..760)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS61165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_09280"
                     /product="hypothetical protein"
                     /protein_id="WP_186403565.1"
                     /transl_table=11
                     /translation="MTLSGGSKSRTLLAAAGLAAGLTAALTLGPVAAQGATIDTMAAQG
                     DVALGSQACAGPFEAGAKDIVAASGSAFQLSKFGVPVGVPANFELRRGEPGTDFFSDAK
                     VVQRATTDFFATSVQAGDPLLPGAFWVCVSAAPGDVVSRVPVHYKLFLGNGLPA"
     misc_feature    861..876
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            967..1701
                     /locus_tag="BKM31_RS09325"
                     /old_locus_tag="BKM31_09285"
     CDS             967..1701
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024836.4"
                     /locus_tag="BKM31_RS09325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09285"
                     /product="GNAT family N-acyltransferase"
                     /protein_id="WP_080037768.1"
                     /transl_table=11
                     /translation="MTISLDPGSLDTGCYTVGMATTPADLQAAQRLRYTVFAGEMGARL
                     DSPVSGLDADRFDAYCDHLLVRAGDEVVGTYRLLPPGRTDRLYSDGEFDLAALRPLRKG
                     LVEAGRTCVHPDHRDGAVVALMWAGIARYMVAGGHQWLAGCCSVPLDDGGAVAAAVMER
                     VPLGPEEHRVRPRTPWRRPAGVGLPDRFVPPPLLRGYLRLGSWVCGAPAHDRDFGTADF
                     FMLLSMANVNARYLRFFLGEPL"
     misc_feature    complement(1962..1980)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.71"
                     /tool="antismash"
     gene            2120..2425
                     /locus_tag="BKM31_RS62160"
     CDS             2120..2425
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013702.4"
                     /locus_tag="BKM31_RS62160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_268967007.1"
                     /transl_table=11
                     /translation="MFIDRERLMALPGAVAAVADALRAGDTVVAFPEGTTWCGRGMGGF
                     RPAVFQAAIDAGAVVRPATLRYREGPRPSTRACFVGTTRCWRPCCGWPPPATWSWR"
     gene            2392..2556
                     /locus_tag="BKM31_RS62165"
     CDS             2392..2556
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS62165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_230466072.1"
                     /transl_table=11
                     /translation="MAATRDLVVEVTLLPPVTPAPGSGGPSARAELAAIAESRVRAGVP
                     GRHLPGEGV"
     gene            2688..2957
                     /locus_tag="BKM31_RS09335"
                     /old_locus_tag="BKM31_09295"
     CDS             2688..2957
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF041742.1"
                     /locus_tag="BKM31_RS09335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09295"
                     /product="WGxxGxxG family protein"
                     /protein_id="WP_080037769.1"
                     /transl_table=11
                     /translation="MRKTLTGLGLAFFLTLAPAAAATADTPVQPVAQSQVTPAPQDNNR
                     DDGGGNAGLWGLLGLLGLLGMAGMRKQRDHVGTAEHMQHRSTRP"
     cand_cluster    2948..14981
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2948..14981
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[7947:9981](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(7948..9981)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     misc_feature    complement(3061..3072)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.36"
                     /tool="antismash"
     gene            3076..3459
                     /locus_tag="BKM31_RS09340"
                     /old_locus_tag="BKM31_09300"
     CDS             3076..3459
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS09340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_09300"
                     /product="hypothetical protein"
                     /protein_id="WP_080037770.1"
                     /transl_table=11
                     /translation="MDKKWASVRALFVAVLAISVATLGVTAVVGGNWVMWLRGAAVAAA
                     SVWLVALTGQAARGRRAAYVRIRFVSVAAPLGIVLILLAPDSGYPGWMKAEQAVVGVLV
                     AAVALIVNRRAVREAYPKGGKLG"
     gene            3461..4066
                     /locus_tag="BKM31_RS09345"
                     /old_locus_tag="BKM31_09305"
     CDS             3461..4066
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="BKM31_RS09345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09305"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_080037771.1"
                     /transl_table=11
                     /translation="MRSSGTRQAATEARRAQIASAAIAVLAERGYAETTFEAICERAGL
                     SSKRLITYHFASKDRLLEAVVEQVVADAAAFMRPALDAAAGARAQLEAFIRANLAFVAR
                     HPGHVRAVRQIAFNQAPVGGQERDAALARLAGLLADGQRTGAFRAFDPAVMAAALRACL
                     DTMAERVADGLDADACADELVELFDRATRADPSPGRPV"
     gene            complement(4096..4782)
                     /gene="aztA"
                     /locus_tag="BKM31_RS09350"
                     /old_locus_tag="BKM31_09310"
     CDS             complement(4096..4782)
                     /codon_start=1
                     /gene="aztA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017596641.1"
                     /locus_tag="BKM31_RS09350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09310"
                     /product="zinc ABC transporter ATP-binding protein AztA"
                     /protein_id="WP_080037772.1"
                     /transl_table=11
                     /translation="MKVTDAVVLSEVTAGYGRRTVLRGLSARLPRPGVTTVVGPNGSGK
                     STLLGVLTGIIRPAGGTVDLGGAGRIGYVAQRDAVSDALPITVREAVSMGRWASRGPWR
                     RLTAYDRAVVETCMAALDLTPLAAHRLSTLSGGQRQRVLLAQGLAQEPDLLLLDEPMTG
                     LDATAARQIAGVLDQERARGVTIVHVTHDPAAALRADHCLLLDGGRLLAEGPPATVLHR
                     SDRPAG"
     misc_feature    4799..4814
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    complement(4801..4815)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.19"
                     /tool="antismash"
     misc_feature    complement(4802..4817)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.22"
                     /tool="antismash"
     gene            complement(4840..5880)
                     /locus_tag="BKM31_RS09355"
                     /old_locus_tag="BKM31_09315"
     CDS             complement(4840..5880)
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (extras)
                     Sulfotransfer_3: Sulfotransferase domain"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024860.4"
                     /locus_tag="BKM31_RS09355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09315"
                     /product="sulfotransferase"
                     /protein_id="WP_080037773.1"
                     /transl_table=11
                     /translation="MDLTIVVGTGRCGSTLLSRILREHPDVLSVSEFFSTLGVGRKLPT
                     GELDGAELWGLLSAPATFLDALIRDGLKPPELYYPYGKGRFDPATGVPVICHSVLPLLT
                     DDPDGLFDRLAAEIPSWPRRPAADQYRHVFRLLAGLYGRRFVIERSGASLVMVERLRRL
                     FPEARFVHLHRDGPDCALSMSRHPSFRWQTLAISAVRAAGLPPTATLEEVEAALPARFR
                     GLICPPYNADLLMGYPIPVHVFGAQWWSAMVCDGVASLRELPREAWISMSYEALLRGPE
                     AELRRLAEFAGLPVPARWLEAARRLVDPGRAGRARADLDAESLAALRAACEPGAAAIAA
                     AEHALS"
     misc_feature    5980..5993
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.55"
                     /tool="antismash"
     gene            5993..6895
                     /locus_tag="BKM31_RS59460"
                     /old_locus_tag="BKM31_09320"
     CDS             5993..6895
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="BKM31_RS59460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09320"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_186403531.1"
                     /transl_table=11
                     /translation="MAVLSAAGLSAGYRGPAVLHEVRLDYDPGLHVLLGPNGAGKTTLF
                     RVLSGVLPPRAGGVLVDGADPYADAMAKLLVGLAAHRAALAPRLSVADNLGYWARVLRL
                     PAPTRQRRVEQVIDTMRLTDIAGQKAGSLSRGQAQRVGVAKALLGDPPVLLLDEPTAGL
                     DPGMAAGLRERLRLLADAGRTIVVSTHELAEASELADDVTVLHQGRVVARGEPGELRQR
                     LVGQGYRLRVRGHGDLLGALRRLGYAPEAHGHDGATVQVSGEEETERLVAALVRDGVGI
                     REATAAGNPLQDVYLHLQG"
     misc_feature    6089..6091
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6892..7698
                     /locus_tag="BKM31_RS09365"
                     /old_locus_tag="BKM31_09325"
     CDS             6892..7698
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS09365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_09325"
                     /product="hypothetical protein"
                     /protein_id="WP_155126793.1"
                     /transl_table=11
                     /translation="MSGVPGAFALCGAILWRVRREGVRDLLSAVVPFVVLLVVLSVLPL
                     VAGHGIKGAAVAAAVGARYGADANMVVVGLLLLITPGLAALFGAIGVTRSVQGLVGSEV
                     SRGGMEELLSAPYTPGGIAAAVLGYALVVATGFWAVMTAAGALAITVVLLLSGARLTLD
                     AGYLTLALLLPLLCAWASAGLTLMVSLLFPRLTQLGAGVNVAGGSLGNGLALLPALGTL
                     LALLYGTVSLGPVKLFLMAGGVTVVITVAAVAIVAGKFRPETVLDS"
     misc_feature    complement(7700..7714)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.51"
                     /tool="antismash"
     misc_feature    7704..7722
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.08"
                     /tool="antismash"
     gene            7720..7941
                     /locus_tag="BKM31_RS09370"
                     /old_locus_tag="BKM31_09330"
     CDS             7720..7941
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS09370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_09330"
                     /product="hypothetical protein"
                     /protein_id="WP_155126796.1"
                     /transl_table=11
                     /translation="MGMIPDRIVRCSDGHLYTAQWAPFFSLRAVRLGSRRFARCPVDGR
                     WRLVTTVEPRDLTEAEIEEAKRHHAGLQ"
     misc_feature    complement(7733..7747)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.14"
                     /tool="antismash"
     gene            complement(7948..9981)
                     /locus_tag="BKM31_RS09375"
                     /old_locus_tag="BKM31_09335"
     CDS             complement(7948..9981)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03975.1"
                     /locus_tag="BKM31_RS09375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09335"
                     /product="RiPP maturation radical SAM C-methyltransferase"
                     /protein_id="WP_268966943.1"
                     /sec_met_domain="TIGR03975 (E-value: 1.1e-203, bitscore:
                     677.3, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.2e-15, bitscore: 56.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVCLVSMPYAGLPRPSMGLSLLKGILIAEGVETVVANANLWFAE
                     SVGLELYHLCANHAPTEFLMGEWTFADVAFPEAEYPGARDGDERYLAQIADSCGRFFGA
                     YGRDGGDRLVADLVSLREMATKFVDEAARRVLASGARVVGCTSTFEQHAASLALLRRVR
                     ELDPAVITMMGGANCETVMGEATHRCFPWVDYVVSGEADGLIAGLCRLVLAQGRDVPPE
                     QLPPGVLGPRSREGGGAGFRARGPGVLDLHVRRPRGKALPRALFRDLDSLPVPEFDDYF
                     AEVAASPLRPNIRPGLPLETSRGCWWGDVHQCTFCGLNGSSMAFRSKSPERVLAEVREL
                     ERRHGISDFEVVDNILDMAYFRTVLPRLAADDRPRRLFYEVKANLTRKQVELLVRAGVT
                     WVQPGIESLHSEVLALMDKGVRGWQNVQLLKWARELGLRLSWSLLWGFPGEHDHYYRTM
                     AGWLPLLEHLQAPNGLSRLRYDRYSVYHQRAGQLGLTLTPISAMAHVYPLDRADLDDLT
                     YFFTAEPESDTLDLAAFSRADVRERPGTVAVYEAVREWRAAFRRHLPPILSLVDRDGVL
                     DIMDSRGCARRWRTTLSGLARAVYLAADAAPRADRIADAVNRDFDVRASADEVREVVDE
                     LVADRLVLPIDGRLVALAVKGDLPALPQHTEFPGGHVSADPS"
     gene            complement(10001..11458)
                     /locus_tag="BKM31_RS09380"
                     /old_locus_tag="BKM31_09340"
     CDS             complement(10001..11458)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: PoyD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Proteusin_Epimerase_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04517.1"
                     /locus_tag="BKM31_RS09380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09340"
                     /product="radical SAM family RiPP maturation amino acid
                     epimerase"
                     /protein_id="WP_080037777.1"
                     /sec_met_domain="PoyD (E-value: 6.8e-130, bitscore: 433.2,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Proteusin_Epimerase_RRE (E-value: 1.2e-09,
                     bitscore: 37.5, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAREPLDTVFPLLGELSDVPASYLRDVAHTKRALERWTMDPAFRA
                     AFEADPEAALKDLGSPLRPGEVTPFLDPAGKAAINGPRRSEYPASVLRYCAYIQEKIAH
                     RERLRREGEPANRTMAAWRRRQINRCRGELGAHRADAIVHAPAAFELSKGCTVGCWFCG
                     VAAPRFDHTWPYTEPNAALWRGVLGALREVVGDCAAQSFLYWATDPLDNPDYERFLVDF
                     HEVMGRCPQTTTALAHADVERTRRLLRLTSSMGSAIDRFSIISINWLDRVHEAFSPEEL
                     LRVECVPQNREAAIPQVKANAGRARKFSRKRGDELVPPGEGSTIACVSGFLFNLVERSV
                     RLITPCDATDRWPLGYWVLDQAEFGTPGELRDVLQSMISTRMRPALRVEDTVRLRPGLL
                     PEVENGELRLTSRGNRVVIRDQPGPGDLAALFTGGSCTAAELARSRRHTAGVPMEETFA
                     LLDFLFAEGCLDEEPSADTDPAVYAVR"
     aSDomain        complement(10031..10306)
                     /aSDomain="Proteusin_Epimerase_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing epimerase in a proteusin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BKM31_RS09380_Proteusin_Epimerase_RRE
                     .1"
                     /evalue="2.90E-12"
                     /identifier="RREFam010.1"
                     /label="BKM31_RS09380"
                     /locus_tag="BKM31_RS09380"
                     /protein_end="476"
                     /protein_start="384"
                     /score="37.5"
                     /tool="antismash"
                     /translation="ALRVEDTVRLRPGLLPEVENGELRLTSRGNRVVIRDQPGPGDLAA
                     LFTGGSCTAAELARSRRHTAGVPMEETFALLDFLFAEGCLDEEPSAD"
     gene            complement(11501..11983)
                     /locus_tag="BKM31_RS09385"
                     /old_locus_tag="BKM31_09345"
     CDS             complement(11501..11983)
                     /EC_number="4.2.1.84"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0046914 - transition metal ion binding
                     [Evidence IEA]"
                     /GO_process="GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014973.4"
                     /locus_tag="BKM31_RS09385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09345"
                     /product="nitrile hydratase subunit alpha"
                     /protein_id="WP_080037778.1"
                     /transl_table=11
                     /translation="MTATTDRVLDGDRAATIMAMVTARAWRDPEYKDRLLREPAAVLTE
                     EGLDVPEGIELRVLEDTPAVRHVNLAREAGDVRQVIGGLPGALEVPEGGELRLVRNSEH
                     VRYIVLRTPPAGIDPAMTSETTLSHHTAPFIWAVEAVVVGSTVSIVAEVVGAVVLT"
     misc_feature    12163..12181
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.01"
                     /tool="antismash"
     misc_feature    12189..12203
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.67"
                     /tool="antismash"
     gene            complement(12198..12893)
                     /locus_tag="BKM31_RS09390"
                     /old_locus_tag="BKM31_09350"
     CDS             complement(12198..12893)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LmbU"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038070.1"
                     /locus_tag="BKM31_RS09390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09350"
                     /product="LmbU family transcriptional regulator"
                     /protein_id="WP_222107177.1"
                     /sec_met_domain="LmbU (E-value: 1.5e-71, bitscore: 239.6,
                     seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQRQINAGGSRRIAQRDRSGGINGQLTLGSDTVPGRLSLRLPEN
                     TQLSTWSQIGQRILLIGNSTAWWLGDWLIFGQDKFPKRYQRAIQETSLDYQTLRNYAWV
                     ARRFPVSRRRDTVSFQHHAAVAALPEAEQDLWLDRATAFGWSLRELRKQLRAARAGSAA
                     AADNVEATLRLKVSQEKVKTWQAAAAAVHQDVLEWMVAVMDRAAGDAIDPPDSAAPGNE
                     YPPVGAAED"
     misc_feature    complement(12600..12602)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12768..12770)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12877..12893)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.29"
                     /tool="antismash"
     gene            complement(13068..13877)
                     /locus_tag="BKM31_RS09395"
                     /old_locus_tag="BKM31_09355"
     CDS             complement(13068..13877)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.4"
                     /locus_tag="BKM31_RS09395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09355"
                     /product="phosphotransferase"
                     /protein_id="WP_155126802.1"
                     /sec_met_domain="APH (E-value: 1.5e-08, bitscore: 34.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDQVEVPLLSARGVVARRGGTVLRAAGPWSATVQALLRHLEEA
                     GFEGAPRVVGSGFEPGSGRETLTFVEGGFVRLGQWSDEAAHALGRLLRDLHTATATFAE
                     PGDATWQPWHGRDLGRRPRVFGHCDTGPWNVVVRGGLPVAFIDWEVAGPVDPLVEVAQL
                     CWLNSHLHDDEVAALAGLRPLAERLHVLRLMIDGYGLTAGDREELVEHMILVAVQDAAA
                     LAPVTITPQAGGEPGPSRSVVHGMAWRLRSAAWMQRHWDVLERAVRT"
     misc_feature    complement(13926..13942)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.75"
                     /tool="antismash"
     gene            13947..14501
                     /locus_tag="BKM31_RS09400"
                     /old_locus_tag="BKM31_09360"
     CDS             13947..14501
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /locus_tag="BKM31_RS09400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09360"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_080037780.1"
                     /transl_table=11
                     /translation="MSHVRTLSAAEISSERLLLRRALRAADREAFVELSTDPDVQSHLG
                     GPRPRSEAEQRFEQVLAGGGETRPGNYAIADRATDRFLGTLMLSHRPPGETGQAGEELE
                     LGYVLRRSAWGAGLAFEAATAALRAAAGELPDQPVVLVTQTANERSMNLAARLGFRPVR
                     TFEEYGAEQTLCTAPLSLWSS"
     gene            complement(14523..14876)
                     /locus_tag="BKM31_RS09405"
                     /old_locus_tag="BKM31_09365"
     CDS             complement(14523..14876)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022443.4"
                     /locus_tag="BKM31_RS09405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09365"
                     /product="DUF2809 domain-containing protein"
                     /protein_id="WP_186403533.1"
                     /transl_table=11
                     /translation="MVLLGGLALAVGAFVLFYRGPGQPFIRGYVSDVVATMLVYAFLGL
                     LWRTTAVRRALATAAVAAGVELYQMVGMTPPGIGGVLVGAFPDPWDLVAYAIGVVAALA
                     WERRWVRSGDQPG"
     gene            complement(14967..16205)
                     /locus_tag="BKM31_RS09410"
                     /old_locus_tag="BKM31_09370"
     CDS             complement(14967..16205)
                     /NRPS_PKS="Domain: Aminotran_5 (32-398). E-value: 1e-57.
                     Score: 187.7. Matches aSDomain:
                     nrpspksdomains_BKM31_RS09410_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890907.1"
                     /locus_tag="BKM31_RS09410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09370"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_080037782.1"
                     /sec_met_domain="Aminotran_5 (E-value: 8.1e-50, bitscore:
                     169.2, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.5e-06,
                     bitscore: 25.6, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDDNSASVISTESLLDIAALRADTPGAEQVVHFNNAGCGLLAAP
                     VLAAMVEHLQLEASIGGYEAAAARAEQVRGFYTELAALINCAPGNIAFAGSATHAFSTA
                     LSAIPFEAGDVILTTRNDFISNQIAFLSLGKRLGVRVVHAPDLPEGGVDVAAMARLMRE
                     HRPRLVAATHIPTNSGLVQPVAEIGRHCRELGLLYLVDACQSVGQYPIDVAEIGCDLLT
                     ATCRKFLRGPRGSGFLYVSDRVLREGYEPLFIDMYGARWVAPDRYQPVETAARFEDWEF
                     PYAIVLGCAAAARYARQVGMDAIARRTPALAAGLRDRLAGLPGVRVLDRGRRLGALVTF
                     AVDGWEAEPFKAAMDARRINSALSFRHFAQFDFGDKDVDWCLRLSPHYYNTEQEVDQVV
                     EAVADLVTGRRAP"
     aSDomain        complement(15012..16109)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS09410_Aminotran_5.1"
                     /evalue="1.00E-57"
                     /label="BKM31_RS09410_Aminotran_5.1"
                     /locus_tag="BKM31_RS09410"
                     /protein_end="398"
                     /protein_start="32"
                     /score="187.7"
                     /tool="antismash"
                     /translation="HFNNAGCGLLAAPVLAAMVEHLQLEASIGGYEAAAARAEQVRGFY
                     TELAALINCAPGNIAFAGSATHAFSTALSAIPFEAGDVILTTRNDFISNQIAFLSLGKR
                     LGVRVVHAPDLPEGGVDVAAMARLMREHRPRLVAATHIPTNSGLVQPVAEIGRHCRELG
                     LLYLVDACQSVGQYPIDVAEIGCDLLTATCRKFLRGPRGSGFLYVSDRVLREGYEPLFI
                     DMYGARWVAPDRYQPVETAARFEDWEFPYAIVLGCAAAARYARQVGMDAIARRTPALAA
                     GLRDRLAGLPGVRVLDRGRRLGALVTFAVDGWEAEPFKAAMDARRINSALSFRHFAQFD
                     FGDKDVDWCLRLSPHYYNTEQEVDQV"
     gene            16204..17595
                     /locus_tag="BKM31_RS09415"
                     /old_locus_tag="BKM31_09375"
     CDS             16204..17595
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (143-457). E-value:
                     8.2e-26. Score: 82.9. Matches aSDomain:
                     nrpspksdomains_BKM31_RS09415_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655131.1"
                     /locus_tag="BKM31_RS09415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09375"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_155126805.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.9e-23, bitscore:
                     82.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 0.00012,
                     bitscore: 20.8, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDSSSSAELAVAMRAMIDRLAPGDRLPSSRELIRRYQVGPGTVA
                     RAIAMLAAEGLVVTRSGSGTYVTARARRRTDVADTAWQTVTLADRSVDTRLLTGTAGTA
                     PAGTILLDGGYLHRSLQPTRILTAALARAARRPDAWDRAPATGLEALRTVFAAMIGGGL
                     TADDLLITSGGQSALSMTFRAIAAPGDPVLVESPTYPGAIAAARAAGLRPVPVPMDADG
                     LRPDLLADAFALTRARLLYCQPTYHNPTGAVLAPDRRPQVIDAARAAGAFVIEDDFARH
                     LGHGTPMPRPLLADDRHGTVIHLTSLTKPAAPSLRIGALAARGPVMERLRAIRLVDDFF
                     VTRPLQETALELLSSPAWDRHVRSLAAALRERCATLAGALSRELPHWTLIGPPRGGLHL
                     WARLPHGAGTVADAALRHGVAVSAGDRYFATELPAAYLRLSFAAAADRDELVEAAHRLA
                     AATSH"
     aSDomain        16633..17574
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS09415_Aminotran_1_2.1"
                     /evalue="8.20E-26"
                     /label="BKM31_RS09415_Aminotran_1_2.1"
                     /locus_tag="BKM31_RS09415"
                     /protein_end="457"
                     /protein_start="143"
                     /score="82.9"
                     /tool="antismash"
                     /translation="PATGLEALRTVFAAMIGGGLTADDLLITSGGQSALSMTFRAIAAP
                     GDPVLVESPTYPGAIAAARAAGLRPVPVPMDADGLRPDLLADAFALTRARLLYCQPTYH
                     NPTGAVLAPDRRPQVIDAARAAGAFVIEDDFARHLGHGTPMPRPLLADDRHGTVIHLTS
                     LTKPAAPSLRIGALAARGPVMERLRAIRLVDDFFVTRPLQETALELLSSPAWDRHVRSL
                     AAALRERCATLAGALSRELPHWTLIGPPRGGLHLWARLPHGAGTVADAALRHGVAVSAG
                     DRYFATELPAAYLRLSFAAAADRDELVEAAHRL"
     gene            17833..19065
                     /locus_tag="BKM31_RS09420"
                     /old_locus_tag="BKM31_09380"
     CDS             17833..19065
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="BKM31_RS09420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09380"
                     /product="cytochrome P450"
                     /protein_id="WP_080037783.1"
                     /sec_met_domain="p450 (E-value: 8.2e-12, bitscore: 44.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPAAPNVPFLDVLDPAFDFDAPEVYAAQAESWYADSPFGLLVL
                     RYEEASDLLRDRRLTHDGRRYLEMHGITSGPIHDWFVPMIVNHDGDVHRRLRGLMNKAF
                     TARRITRLRPFVRERAEELTDGLDDGGTHDFVAEFGIRLPLAVMCRLLGVRPEDYDLFG
                     TWTADLGLIFSLSGGGDVVARLERAVDGLNDYADHLIDDKLVRPSDDLSSDLVAAYQAG
                     DGQVSREELRNLLVTLVFAAHDTTRHQLANAMVVFARHPEQWVLLGRRPELVSQAVEEV
                     MRWQPSSTSIYRFAAEDFTYKGLAVEKGMYLTMCVKAAQRDPRAYKDAGRFDITEVREL
                     PSLQFGGGPHHCLGAALARVEVGEALSVLAARLGPPSLMGPPAWPGPLGIQGPETLPLR
                     FGPGLTRPERP"
     gene            complement(19043..19594)
                     /locus_tag="BKM31_RS09425"
                     /old_locus_tag="BKM31_09385"
     CDS             complement(19043..19594)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543426.1"
                     /locus_tag="BKM31_RS09425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09385"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_080037784.1"
                     /transl_table=11
                     /translation="MERADAARNRARILEAAALLFAERSPQDVTMDDIAKKAGVGRGTL
                     YRRYPDRASIAVALLDEHERALQERLLRGEPPLGPGAPPAERLAAFYAAMVRLLEDHSH
                     LVLGSEVGRSRFETGAYGFWRAHVRALLVAAGTPGRDALVDVLLAPLAPEVYDYQRTVL
                     GLTTEQITRALTRLTAVLDG"
     misc_feature    complement(19625..19645)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.55"
                     /tool="antismash"
     misc_feature    19636..19650
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.15"
                     /tool="antismash"
     gene            19674..20303
                     /locus_tag="BKM31_RS09430"
                     /old_locus_tag="BKM31_09390"
     CDS             19674..20303
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890664.1"
                     /locus_tag="BKM31_RS09430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09390"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_080037785.1"
                     /transl_table=11
                     /translation="MLLHLDASARRHASFSRKLSSVYAETWRAAHPDARYVYRDLAAHP
                     VPHIGEAWTELCDHILEHEITDISRYREAARTPAQQAAWAVVEPLLDEVVAADVILIGT
                     PMYNYSIPSTLKAWLDQITFPKMSLEGRSFVVTSARGGAYGPGTPREPYDHQERYLRDF
                     FKGHFRVEDVTFIHAELVNARLDPALAHLREQHEQSLAAALKEAAQ"
     gene            20300..20614
                     /locus_tag="BKM31_RS09435"
                     /old_locus_tag="BKM31_09395"
     CDS             20300..20614
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543424.1"
                     /locus_tag="BKM31_RS09435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_09395"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_080037786.1"
                     /transl_table=11
                     /translation="MSWLTLLLAGLVEVAWSQSIKPTQNFTRPLPTLVSLALMAVAVWL
                     LSRAMNTLPVGTAYAVFTGIGAVGAITLGIVVNDDPVSVGRMAALALIVGGIVLARITT
                     "
     misc_feature    complement(20663..20678)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.58"
                     /tool="antismash"
ORIGIN
        1 gccgagctgc gcaagacggc cgagcacgtg ctctggcacg gcgccgactg cgcccgccgg
       61 gccagctcgg gcgtgcccgt cgagacggac ctgcacgagg gccccgtcgc cgagcgcctt
      121 gttggagctc tcccaggacg ccgcgctggt cgtggtcggc tcgcgcgggc tcggcgccct
      181 gtccagggcg gtcgtcggcg cggtggccga gtacgtcgcc gcccacgccg cgccgcgcca
      241 cccccaccgc gcaggggtgg gcgttccgcc gtccggagcc cgttcaggcg ggcaggccgt
      301 tgccgaggaa cagcttgtag tgcacgggga cgcgcgagac cacgtcgccg ggtgccgcgc
      361 tcacgcacac ccagaacgcg ccgggcagga gcgggtcgcc cgcctgcacg gaggtggcga
      421 agaagtcggt ggtggcccgc tgcaccacct tggcgtcgct gaagaagtcg gtgccgggct
      481 cgccgcgccg cagctcgaag ttggcgggga cgccgacggg caccccgaac ttgctgagct
      541 ggaaggccga tccgctggcg gcgacgatgt ccttcgcgcc cgcctcgaac gggccggcgc
      601 acgcctggct gcccagcgcg acgtcaccct gggcggccat cgtgtcgatg gtggcgccct
      661 gggcggcgac ggggccgagc gtgagcgccg cggtgagccc cgcggccagc ccggccgccg
      721 cgagcagcgt ccggctcttg ctgccgcctg aaagggtcat ggtggtctcc tgaggtcgtg
      781 ggcgcggtgt ccggggccgg cgccctacct tcatgggcgt gacagcgggg ttccacccgt
      841 gccaccgcgt tccaggggat ctgcggattt tttctctcgg tcgcctggct gccgccggcg
      901 tgagacgtgc cggtcatgtc cgcatgtcga cataggcgcg agaacccttc agggaaggac
      961 gcgcccatga cgatctctct cgaccctggc tctctcgaca ccggttgcta cacggtcggc
     1021 atggccacca cccccgccga cctccaggcg gcccagcggc tgcggtacac ggtcttcgcc
     1081 ggggagatgg gggcgcggct cgacagcccg gtctccggcc tcgacgccga ccggttcgac
     1141 gcctactgcg accacctgct cgtccgggcc ggggacgagg tcgtggggac gtaccggctg
     1201 ctgccgccgg gacgtacgga ccggctctac tccgacggcg agttcgacct cgcggcgctc
     1261 aggcccctca ggaagggcct ggtggaggcg ggccgcacct gcgtccaccc ggaccaccgg
     1321 gacggcgcgg tggtcgcgct gatgtgggcg gggatcgccc gttacatggt cgcgggcggc
     1381 caccagtggc tggcgggctg ctgctcggtg ccgctcgacg acggcggcgc ggtggccgcc
     1441 gccgtgatgg agcgggtgcc gctcggcccg gaggagcacc gggtgcggcc gcgcacgccg
     1501 tggcggcggc cggccggggt ggggctgccc gaccggttcg tgccgccgcc gctgctgcgc
     1561 ggctatctgc ggctggggtc gtgggtgtgc ggggcgcccg cgcacgaccg ggacttcggc
     1621 acggccgact tcttcatgct gctgtcgatg gccaacgtca acgcccgcta cctgcgcttc
     1681 ttcctcggcg agcccctgtg agcaccgtcc tgccgccacc ggcggcgcgg ctcaacccgt
     1741 ggcgtcccct ggggccgtgc acgcccgcca cctgtgtcgg ggacccggcc gccgtggtga
     1801 gcccgctccg gcgcctggcg cgcctcctgg gcgtcgtcgc ggtggtgctg ggtggcatgc
     1861 cggtggccct ggcctgccgg atgctgcccc gggtgcggcc cacgcggctg tgggcgcggc
     1921 tgttgctgcg ggtgctcggc atccgcctgg aggtgcgcgg ggctgttgat gcttccggta
     1981 cgggagcgct cgtggtggcc aaccacatct cctggctcga ccccctcgtg gtggccgcca
     2041 cggtgccgtc caggccgctc gccaagcggg aggtcgccgg ctggcccgtc atcgggacgc
     2101 tggtggcggg gccggggcgc tgttcatcga cagggagcgg ctcatggcgc tgcccggcgc
     2161 cgtggcggcc gtggcggacg cgctgcgggc gggggacacg gtggtcgcct tccccgaggg
     2221 caccacgtgg tgcgggcggg ggatgggcgg cttccgcccg gcggtgttcc aggcggcgat
     2281 cgacgcgggg gccgtcgtgc ggccggccac gctgcgctac cgcgaggggc cgcggccctc
     2341 cacccgcgcc tgcttcgtgg ggacgactcg ctgctggcgt ccctgctgcg ggtggccgcc
     2401 acccgcgacc tggtcgtgga ggtgacgctg ctgcctcccg tgacgcccgc gcccggctcc
     2461 ggcggcccgt ccgcgagagc ggagctggcc gcgatcgccg agtcccgcgt acgtgcgggc
     2521 gtgcccggcc gccacctgcc gggagaaggc gtttgatgcg gccaggacga tggtaggggg
     2581 cttttagcag gggatctgga gatcgccccg ctatcggaag ccttcgtcgg agaaggcgtg
     2641 ataggcggtc tccgcggttg ccgagaccgc cggatcgggg gaacccaatg cgcaagacgc
     2701 tcaccgggct gggcctggcg ttcttcttga cgctggcacc agccgccgca gcgaccgccg
     2761 acacaccggt ccagccggtc gctcagagcc aggtgacgcc cgcaccacag gacaacaaca
     2821 gggacgacgg cggcggcaac gccgggctgt ggggcctgct gggcctgctc ggcctgctgg
     2881 gcatggccgg catgcgtaag cagcgcgacc acgtaggcac cgccgagcac atgcagcacc
     2941 gttccacgcg gccgtaagag ggccgccccc cggccccgcg ccggggtgaa cgttcactag
     3001 gtgacacggc cgccggcagg tcggccgtgt cgccatgtct tgcggtttct tatccggccg
     3061 gataacttta tccgcatgga taagaaatgg gcgtccgtgc gggcgctctt cgtcgccgtc
     3121 ctcgccatct ccgtcgcgac gctcggcgtc accgccgtcg tcggcggcaa ctgggtcatg
     3181 tggctgcgcg gcgccgccgt ggccgctgcc tccgtctggc tcgtcgccct gaccgggcag
     3241 gccgcccgag gcaggagggc cgcgtacgtg cgcatccggt tcgtcagcgt cgccgcgccc
     3301 ctcgggatcg tgctcatcct gctcgccccc gacagcggct accccggctg gatgaaggcg
     3361 gagcaggccg tggtcggcgt cctcgtcgcc gccgtcgcgc tgatcgtcaa ccggcgggcc
     3421 gtgcgggagg cgtaccccaa aggtggcaag ctggggtgac atgagaagct ccgggacccg
     3481 tcaggcggcc accgaggcgc gcagggcgca gatcgcctcc gccgcgatcg ccgtgctcgc
     3541 cgagcgcggc tacgcggaga ccacgttcga ggccatctgc gagcgggccg ggctcagcag
     3601 caaacgcctc atcacctacc acttcgccag caaggaccgg ctgctcgaag ccgtcgtgga
     3661 gcaggtcgtc gccgacgccg cggccttcat gcgccccgcg ctggacgccg ccgccggcgc
     3721 ccgcgcccag ctcgaggcgt tcatcagagc caacctcgcc ttcgtcgccc gccatcccgg
     3781 gcacgtgcgc gcggtgcggc agatcgcctt caaccaggcg cccgtgggcg ggcaggagcg
     3841 tgacgccgcc ctcgcccggc tggccgggct gctcgccgac gggcagcgca cgggggcctt
     3901 ccgcgcgttc gaccccgcgg tgatggcggc ggccctgcgc gcctgcctcg acacgatggc
     3961 cgagcgggtg gccgacgggc tcgacgccga cgcctgcgcg gacgagctcg tcgagctgtt
     4021 cgaccgcgcc acccgcgccg atccgtcacc cggccggccg gtctgagccg tcactctggc
     4081 ggccggtccg agttgtcacc cggccggccg gtccgagcgg tgcagcacgg tggcgggcgg
     4141 accctcggcc agcagccggc cgccgtcgag cagcaggcag tgatcggcgc gcagggccgc
     4201 cgccgggtcg tgcgtgacgt gcacgatcgt cacgccacgg gcccgctcct ggtcgagcac
     4261 gccggcgatc tgccgggcgg cggtggcgtc gaggccggtc atgggctcgt ccagcaggag
     4321 caggtcgggc tcctgcgcga gcccctgggc caggagcacg cgctggcgct ggccgcccga
     4381 cagcgtgctc aggcggtgcg cggccagcgg cgtcaggtcg agcgccgcca tgcaggtctc
     4441 cacgaccgcc cggtcgtacg cggtcagccg ccgccacggg ccgcgcgacg cccagcggcc
     4501 catcgacacc gcctcccgca ccgtgatcgg cagcgcgtcg gagaccgcgt cgcgctgcgc
     4561 cacgtacccg atccggccgg cgccgcccag gtcgaccgtg ccgcccgccg ggcggatgat
     4621 cccggtcagc acgccgagca gggtggactt gccggagccg ttcgggccga cgaccgtggt
     4681 gacgcccgga cggggcagcc gggccgacag gccgcgcagg accgtcctgc ggccgtagcc
     4741 ggcggtgacc tcgctgagca cgaccgcgtc ggtgaccttc atgcgccctc cacctgaaac
     4801 tgacaacggt tttcattgta gagggtggag aggatcggct caggagagcg cgtgctccgc
     4861 ggcggcgatc gcggccgcgc ccggctcgca cgccgcgcgc agtgccgcca gcgactcggc
     4921 gtcgagatcg gcccgcgccc ggcccgcccg gcccggatcg accaggcggc gcgccgcctc
     4981 cagccaccgc gccggcaccg gcagtccggc gaactccgcc agccgccgca gctccgcctc
     5041 gggcccgcgc agcagggcct cgtagctcat cgagatccac gcctcccggg gcagctcgcg
     5101 cagggacgcc accccgtcgc acaccatcgc cgaccaccac tgcgcgccga acacgtgcac
     5161 cgggatggga tagcccatca gcaggtcggc gttgtagggc gggcagatca ggccgcggaa
     5221 ccgcgcgggc agcgccgcct ccacctcctc cagcgtggcg gtcggcggca gcccggcggc
     5281 gcgcacggcc gagatggcca gcgtctgcca gcggaaggac gggtgccggc tcatcgacag
     5341 cgcgcagtcg gggccgtcgc ggtgcagatg cacgaagcgc gcctcgggga acagccgccg
     5401 cagccgctcc accatgacga gcgaggcgcc ggagcgctcg atcacgaagc gccgcccgta
     5461 caggccggcg agcaggcgga agacgtgccg gtactggtcg gcggccggac gccggggcca
     5521 ggaagggatc tcggcggcca gccggtcgaa caggccgtcg gggtcgtcgg tgagcagcgg
     5581 cagcacgctg tggcagatca ccggcacgcc ggtcgccggg tcgaagcggc ccttcccgta
     5641 cgggtagtac agctcgggcg gcttcagccc gtccctgatc agggcgtcga ggaaggtcgc
     5701 gggcgccgac agcaggcccc acagctccgc gccgtccagc tccccggtcg ggagtttcct
     5761 gccgacgccc agcgtggaga agaactcgct gacgctgagc acgtcgggat gctcgcgcag
     5821 gatgcgggac aacaatgtcg agccgcaccg cccggtgccc acgacaatgg tgagatccac
     5881 cggccgcctc cttctcgcgt tttttcgtac gcgggcgtgc gggagaaatt gccattacct
     5941 tagcaaggcg ttcatcggct gcccagcgac cgttcttgat agagtgagtt ttatggctgt
     6001 gctcagcgcc gcgggcctgt ccgccggtta ccgcggcccg gccgtcctgc atgaagtgcg
     6061 gctcgattac gaccccgggc tccatgtttt actcggccct aacggcgccg gtaagacgac
     6121 cctgttcagg gtgttgtcgg gagtgctgcc gccgcgcgcg ggcggcgtgc tggtcgacgg
     6181 cgccgacccg tacgccgacg ccatggccaa gctgctcgtc ggcctggcgg cgcaccgggc
     6241 ggctctggcg ccccggctga gcgtcgccga caacctgggc tactgggcgc gggtgctgcg
     6301 cctgcccgcc cccacgcggc agcggcgcgt cgagcaggtc atcgatacca tgcggctcac
     6361 cgacatcgcg ggccagaagg cgggctcgct gagcaggggg caggcgcaac gggtgggcgt
     6421 ggccaaggcg ctgctcggcg acccgcccgt gctgctgctc gacgagccca ccgccgggct
     6481 cgacccgggc atggcggccg ggctgcgcga gcggctgcgc ctgctggccg acgccgggcg
     6541 caccatcgtc gtctccaccc acgagctggc cgaggcgagc gagctggccg acgacgtgac
     6601 cgtcctgcac caggggcggg tggtggcccg cggcgagccg ggcgagctgc ggcagcggct
     6661 ggtcggccag ggctaccggc tgcgcgtgcg cggccacggc gacctgctgg gcgcgctgcg
     6721 gcggctcggc tacgcgcccg aggcgcacgg gcacgacggg gcgaccgtcc aggtgtccgg
     6781 cgaggaggag acggagaggc tggtggcggc gctggtgcgc gacggggtcg ggatccgcga
     6841 ggccacggcg gccggcaacc cgttgcagga cgtctacctg catcttcagg ggtgagcggg
     6901 gtgccgggcg cgttcgccct gtgcggggcg atcctgtggc gggtgcgcag ggagggcgtg
     6961 cgcgacctgc tgtccgccgt cgtgccgttc gtcgtgctcc ttgtcgtgct cagcgtgctg
     7021 ccgctggtcg ccgggcacgg gatcaagggc gcggccgtgg ccgccgccgt cggcgcccgc
     7081 tacggcgccg acgccaacat ggtcgtcgtc gggctgctgc tgctcatcac gcccgggctc
     7141 gcggccctgt tcggcgccat cggcgtcacc cgctccgtgc aggggctggt cggctccgaa
     7201 gtgagcaggg gcggcatgga ggagctgctg agcgcgccgt acacgcccgg cggcatcgcc
     7261 gccgccgtgc tcggctacgc cctggtcgtg gccaccggct tctgggcggt catgaccgcg
     7321 gccggcgcgc tggcgatcac cgtcgtgctg ctcctgagcg gcgcgcggct cacgctcgac
     7381 gccggatacc tgacgctcgc gctgctgctg cccctgctgt gcgcgtgggc gagcgccggg
     7441 ctgaccctga tggtcagcct gctctttccg cgcctcaccc aattgggtgc gggcgtgaat
     7501 gtcgcgggcg gcagtctcgg aaacggcctg gcattgctgc cggccctcgg cacgttgctg
     7561 gcgctgcttt acgggacggt ttccctgggg ccggtgaaac tctttctcat ggccggtggg
     7621 gtgaccgtgg tcattaccgt cgcggcggtg gcgatcgtcg ccgggaaatt ccggccggaa
     7681 acggtgctcg actcctgacg atttcctgga gaaaacgaca tgggaatgat tccggatcgt
     7741 atcgtccgtt gttccgacgg gcacctctac acggcgcagt gggcgccgtt cttctccctg
     7801 cgcgccgtac ggctcggctc ccggcgcttc gcccgctgcc cggtcgacgg ccgctggcgg
     7861 ctggtcacca cggtcgagcc gcgcgacctc accgaggccg agatcgagga ggcgaaacgc
     7921 caccacgcgg gcctgcagtg atccctgtca ggacgggtcc gcgctgacgt gcccgccggg
     7981 gaactccgtg tgctgcggca gggcgggcag gtcgcccttc accgccagcg ccacgagccg
     8041 gccgtcgatc ggcagcacca gccggtcggc caccagctcg tccaccacct ctcggacctc
     8101 gtccgccgag gcccgcacgt cgaagtcgcg gttgacggcg tcggcgatcc ggtcggcgcg
     8161 cggtgccgcg tccgccgcca ggtacaccgc gcgggccagg ccgctcagcg tcgtccgcca
     8221 ccggcgggcg cagccgcgcg agtccatgat gtccaggacg ccgtcgcggt ccaccagcga
     8281 caggatgggc ggcaggtgcc ggcggaaggc cgcccgccac tcgcgcaccg cctcgtacac
     8341 cgccacggtg cccggccgct cccgcacgtc ggcccggctg aaggcggcca ggtcgagcgt
     8401 gtccgactct ggctcggcgg tgaagaagta ggtcaggtcg tccaggtccg cccgatccag
     8461 cgggtagacg tgcgccatcg ccgagatcgg cgtcagcgtg agccccagct gcccggcccg
     8521 ctggtggtag acgctgtagc ggtcgtagcg cagcctggac aggccgttcg gggcctggag
     8581 gtgctccagc agcggcagcc agcccgccat ggtccggtag tagtggtcgt gctcgcccgg
     8641 gaaaccccac agcagcgacc acgacagccg cagccccagc tcgcgggccc acttgagcag
     8701 ctgcacgttc tgccagcccc gcacgccctt gtccatgagg gccagcacct cgctgtgcag
     8761 gctctcgatg ccgggctgca cccacgtcac ccccgcccgc accagcagct ccacctgttt
     8821 gcgggtgagg ttcgccttga cctcgtagaa gagccggcgc ggccggtcgt cggcggcgag
     8881 cctgggcagc accgtacgga agtaggccat gtcgaggatg ttgtccacga cctcgaagtc
     8941 gctgatgccg tggcgccgct ccagctcgcg cacctcggcc agcacccgct cgggcgactt
     9001 ggagcggaag gccatgctgc tgccgttcag cccgcagaac gtgcactggt gcacgtcgcc
     9061 ccaccagcag ccgcgcgagg tctccagcgg caggcccggc cggatgttgg ggcgcagcgg
     9121 cgaggccgcg acctccgcga agtagtcgtc gaactccggc accggcaggc tgtccaggtc
     9181 gcggaacagg gcacggggga gcgccttgcc gcgaggtctc cgtacgtgga ggtcgaggac
     9241 gccgggcccg cgcgcacgga aaccggcccc gccgccctcc cgcgaacggg ggccgaggac
     9301 gccgggcggc agctgttccg gcgggacgtc gcggccctgc gcgagcacca ggcggcacag
     9361 gccggcgatc aggccgtccg cctcgcccga gacgacgtag tccacccacg ggaagcaccg
     9421 gtgggtggcc tcgcccatca cggtctcgca gttggccccg cccatcatcg tgatcacggc
     9481 cgggtccagc tcgcggaccc gccgcagcag ggccagcgag gcggcgtgct gctcgaacgt
     9541 ggacgtgcag ccgaccacgc gcgccccgct cgccagcacc cggcgcgcgg cctcgtcgac
     9601 gaacttcgtc gccatctcgc gcaacgacac caggtccgcg accagccggt caccgccatc
     9661 acggccatag gcgccgaaga acctgccgca ggagtcggcg atctgcgcga ggtaccgctc
     9721 gtcgccgtcg cgggcgcccg gatactccgc ctcggggaag gccacgtcgg cgaacgtcca
     9781 ctcgcccatc aggaactcgg tcggcgcgtg gttggcgcac agatggtaga gctccaggcc
     9841 gacgctctcg gcgaaccaga ggttggcgtt ggcgacgacg gtctcgacgc cctcggcgat
     9901 caggatgccc ttgagcaggc tcagccccat ggacgggcgg ggcagcccgg cgtacggcat
     9961 cgaaacgagg catacgtcca cggcagggtc tcccagcgct ctaccggacc gcgtacacgg
    10021 ccgggtcggt gtcggccgag ggctcctcgt ccaggcagcc ctccgcgaac aggaagtcca
    10081 gcagggcgaa cgtctcctcc atcggcacgc cggcggtgtg ccgcctgctc cgggccagct
    10141 ccgcggcggt gcacgacccg ccggtgaaca gggcggccag gtcgccgggg ccgggctggt
    10201 cgcggatgac cacccggttg ccgcgcgagg tcagccgcag ctcgccgttc tcgacctcgg
    10261 gcaggaggcc gggacgcagc cgcacggtgt cctcgacgcg cagcgccggc cgcatgcgcg
    10321 tggagatcat cgactgcagg acgtcgcgca gctcgcccgg cgtgccgaac tcggcctggt
    10381 cgagcaccca gtagccgagc ggccagcggt cggtggcgtc gcagggcgtg atgagccgca
    10441 cggaccgctc gaccaggttg aacaggaagc ccgacacgca cgcgatggtc gagccctcgc
    10501 cgggcggcac cagctcgtcc ccgcgcttgc gggagaactt gcgggcccgg cccgcgttcg
    10561 ccttcacctg cgggatggcc gcctccctgt tctgcgggac gcactccacg cgcagcagct
    10621 cctcagggct gaacgcctcg tggacgcggt cgagccagtt gatcgagatg atcgagaagc
    10681 ggtcgatggc ggagcccatc gagctcgtca ggcgcagcag ccgccgcgtc cgctccacgt
    10741 cggcgtgcgc cagcgcggtc gtggtctgcg ggcagcggcc catgacctcg tggaagtcca
    10801 ccaggaaccg ctcgtagtcg ggattgtcca gggggtcggt cgcccaatac aggaagctct
    10861 gggcggcgca gtcgcccacc acctcccgca gggcgccgag cacgccccgc cacagcgccg
    10921 cgttcggctc ggtgtagggc caggtgtggt cgaaccgggg agcggccacg ccgcagaacc
    10981 agcagccgac ggtgcagccc ttcgacagct cgaaggcggc gggcgcgtgc acgatggcgt
    11041 ccgcgcggtg cgcgccgagc tcgccgcggc accggttgat ctgccgccgc cgccaggccg
    11101 ccatggtccg gttcgcgggc tcgccctcgc ggcgcagccg ctcccggtgg gcgatctttt
    11161 cctggatgta cgcgcagtac cgcagcaccg acgcggggta ctcggaccgg cgcggcccgt
    11221 tgatcgcggc cttcccggcc gggtcgagga agggcgtcac ctcgccgggc cgcagcgggc
    11281 tgcccaggtc cttgagcgcg gcctcggggt cggcctcgaa cgccgcgcgg aaggccggat
    11341 ccatggtcca gcgttcgagg gcccgcttgg tgtgggcgac gtcccgcagg tagctcgccg
    11401 ggacgtccga gagctcaccg agcaggggaa agacggtgtc cagcggttct cgcgccattc
    11461 ttccttctct ctcgtcgagc ctctgctcgg tgcggcgggg tcaggtcagg acgacggcgc
    11521 cgaccacctc ggccacgatg ctcacggtcg acccgacgac gaccgcctcg accgcccaga
    11581 tgaagggcgc ggtgtggtgg ctgagcgtcg tctcggaggt catggccggg tcgatccccg
    11641 ccggcggcgt ccgcaggacg atgtagcgga cgtgctcgga gttcctgacc agccgcagct
    11701 cgccgccctc gggcacctcg agcgcgcccg gcaggccgcc gatcacctgc cggacgtcgc
    11761 ccgcctcgcg cgccaggttg acgtgccgca ccgccggcgt gtcctccagc acgcgcagct
    11821 cgatcccctc gggcacgtcg aggccctcct ccgtgaggac cgcggccggc tcgcgcagca
    11881 accggtcctt gtactcggga tcccgccagg cgcgcgcggt gaccatcgcc atgatcgtgg
    11941 cggcgcggtc tccgtccagc acccggtccg tcgtcgcggt catacgcatt ctcctctgct
    12001 ctcgagccat gctccatgaa acggggatgc gaccgatccg ggtaatcgcg gaaatcggcg
    12061 gcaccggcga ccggaggccg tcggcttttg catgacgcgc gctcgcccga aatgcgacgg
    12121 ggcggggttg tgcggccgag gacctccgcg gaccacggtg aacttgcgtg cgattatgaa
    12181 tatccgggaa tatcctgtca atcctcggcg gcgccgaccg gcggatattc atttcccggg
    12241 gccgcggaat ccggcggatc gatcgcgtcg ccggcggccc ggtccatgac ggccaccatc
    12301 cattccagga cgtcctggtg caccgccgcg gcggccgcct gccaggtctt caccttttcc
    12361 tggctgacct tcagccggag cgtcgcctcc acattgtcgg ccgccgcggc gctgcccgcg
    12421 cgggccgctc tgagctgttt cctgagctcc cgcagcgacc acccgaacgc cgtggcgcgg
    12481 tcgagccaga ggtcctgctc ggcctcggga agggcggcca ccgccgcgtg gtgctggaag
    12541 ctcaccgtgt cccgtcgacg ggacaccggg aaccggcgcg ccacccacgc gtagttccgt
    12601 aatgtctgat agtcgagcga cgtctcctgg atcgcccgct ggtaacgctt gggaaacttg
    12661 tcctggccga atatgagcca gtcgcccagc caccaggcgg tggagttgcc gatgagcagg
    12721 atccgctggc cgatctggct ccacgtcgac aattgcgtgt tttccggtaa acgcaggctc
    12781 aggcgtcctg gaaccgtgtc ggagcccagt gtgagctgac cgttgatacc gcccgaacga
    12841 tcacgctgcg caattctccg gctgccgccc gcgtttattt gccgttgtat cacctcgtgc
    12901 tccctgcgac ggcattgact tgtcgtcact gtcagtgtgg cacggcggcc ggagcctcgc
    12961 cacacggaga tccactgaac tgcgcccggt tattcaagga gatttcctga gcgccttgac
    13021 cggttgtgga acgtgccttt tccatgcgga ttcaagcctg agagggctca ggtgcggacg
    13081 gcgcgctcaa ggacgtccca gtgccgctgc atccaggcgg cgctgcgcag gcgccacgcc
    13141 atgccgtgca ccacgctccg cgacggcccg ggctcgccgc cggcctgggg cgtgatcgtg
    13201 acgggggcca gggcggcggc gtcctgcacg gcgacgagga tcatgtgctc gaccagttcc
    13261 tcgcgatccc cggcggtcag cccgtacccg tcgatcatca ggcgcagcac gtgcagccgc
    13321 tcggcgagcg ggcgcaggcc ggccagcgcg gccacctcgt cgtcgtgcag gtggctgttc
    13381 agccagcaga gctgcgccac ctcgaccagc ggatcgacgg gccccgccac ctcccagtcg
    13441 atgaacgcca ccggcaggcc gccgcggacc acgacgttcc aggggccggt gtcgcagtgg
    13501 ccgaacacgc gcggccgccg cccgagatcg cgtccgtgcc agggctgcca ggtcgcgtcg
    13561 ccgggctcgg cgaaggtggc ggtggcggtg tgcaggtcgc gcagcagccg gccgagcgcg
    13621 tgggccgcct cgtcgctcca ctgccccagc cttacgaagc cgccctcgac gaaggtgagc
    13681 gtctcacgcc cggagcccgg ctcgaagccg ctgccgacca cgcgcggcgc cccctcgaac
    13741 ccggcctcct ccaggtgccg cagcaacgcc tgcaccgtgg ccgaccacgg gcccgccgcg
    13801 cgcagcaccg tcccgccccg gcgggcgacc acgccccggg cgctgagcag cggcacctcc
    13861 acctggtcat ccgtcactgg gccacctccg cggcgggggc ccggccgtcc ccgggccttg
    13921 ggcccatgtt ctatgatcac gggcctatga gccacgtgcg tacgctttcc gccgcggaga
    13981 tctcctcgga gcggctcctg ctgcgcaggg cgttgcgcgc cgccgaccgg gaggcgttcg
    14041 tcgagctgtc gaccgatccc gacgtgcagt cccacctcgg cggcccccgt cctcgcagcg
    14101 aggccgagca gcgcttcgag caggtcctgg ccggcggcgg ggagaccagg cccggcaact
    14161 acgccatcgc ggaccgggcg acggaccgct tcctcggcac gctgatgctc tcccaccggc
    14221 cgcccggcga gaccgggcag gccggcgagg agctggagct gggctacgtc ctgcggcgca
    14281 gcgcctgggg cgccgggctc gcgttcgagg cggcgacggc cgcgctgcgc gccgccgccg
    14341 gcgaactgcc cgaccagccg gtcgtgctcg tcacgcagac cgcgaacgaa cgctccatga
    14401 acctcgccgc ccgcctgggc ttccggccgg tccgcacgtt cgaggagtac ggcgccgagc
    14461 agaccctctg cacggccccg ctctccctgt ggtcctccta ggcggcgcgt acagtccggg
    14521 agtcagccgg gctgatcacc ggatcggacc catcggcgtt cccaggccag agccgcgacc
    14581 accccgatgg cgtaggcgac caggtcccac gggtcgggga acgcgccgac caggacaccg
    14641 ccgatgcccg gcggcgtcat gccgaccatc tggtagagct cgacgccggc ggcgaccgcg
    14701 gccgtggcca gggcgcggcg cacggcggtg gtgcgccaca gcagccccag gaacgcgtag
    14761 accagcatgg tcgcgacgac gtcgctcacg tagccgcgga tgaacggttg ccccgggccc
    14821 cggtagaaga ggacgaacgc gccgacggcg agggcgagac cacccagaag gaccatggca
    14881 cggcgcatgg gatcgacatc ttctccgcat ctctgtgatc aggacgaacc cgatcataga
    14941 gctcgtccct cgaggtcctc ctggggctac ggggcccgcc gcccggtgac gagatccgcg
    15001 accgcctcga cgacctggtc cacctcctgc tcggtgttgt agtagtgcgg tgacaggcgc
    15061 aggcaccagt ccacgtcctt gtcgccgaag tcgaactgcg cgaagtggcg gaagctgagc
    15121 gccgagttga tccggcgcgc gtccatggcg gccttgaacg gctccgcctc ccacccgtcc
    15181 acggcgaacg tgacgagcgc ccccaaccgc cggccccggt cgagcacgcg cacccccggc
    15241 agcccggcga gcctgtcgcg cagcccggcg gccagggcgg gggtgcggcg ggcgatggcg
    15301 tccatgccga cctgccgggc ataacgggcg gcggccgcac agcccagcac gatggcgtac
    15361 gggaactccc agtcctcgaa ccgggcggcc gtctcgaccg gctggtagcg gtccggcgcg
    15421 acccaccggg cgccgtacat gtcgatgaac agcggctcgt acccctcgcg caggacgcgg
    15481 tcggagacgt acaggaagcc cgagccgcgc ggcccgcgca ggaacttgcg gcaggtggcg
    15541 gtcagcaggt cgcagccgat ctccgccacg tcgatcgggt actggccgac cgactggcag
    15601 gcgtccacca ggtacagcag gcccagctcg cggcagtgcc ggccgatctc cgcgaccggc
    15661 tgcaccaggc cggagttggt ggggatgtgc gtggccgcca ccagccgcgg gcggtgctcg
    15721 cgcatcagcc gcgccatggc cgccacgtcc accccgccct ccggcaggtc gggggcgtgc
    15781 acgacgcgca cgccgagcct cttgcccagg gacaggaagg cgatctggtt ggagatgaag
    15841 tcgttgcggg tcgtcaggat gacgtcgccg gcctcgaacg ggatcgccga caacgcggtg
    15901 gagaaggcgt gggtggcgct accggcgaag gcgatgttgc cgggagcgca gttgatcagc
    15961 gcggccagct cggtgtagaa cccgcggacc tgctcggcgc gggcggccgc cgcctcgtag
    16021 ccgccgatgc tcgcttcgag ctgtagatgc tcgaccatcg ccgccagcac gggcgcggcc
    16081 aggaggccgc agccggcgtt gttgaagtgc accacctgct cggcgcccgg ggtgtcggcg
    16141 cgcagggccg cgatgtccag aagcgattct gtcgaaatta cggaagcgct attatcgtct
    16201 ctcatgtcgg atagtagcag ttcggcggag ctggccgtcg cgatgcgggc gatgatcgac
    16261 cggctggcgc cgggcgaccg cctgcccagc agccgcgagc tgatccggcg ctaccaggtc
    16321 ggccccggca ccgtggcgcg ggccatcgcc atgctcgccg ccgagggcct ggtcgtgacc
    16381 cgttcgggca gcggcacgta cgtgacggcc cgggcgcggc ggcgtaccga cgtggccgac
    16441 accgcctggc agacggtcac cctcgccgac cgcagcgtgg acacccggct gctcaccggc
    16501 accgccggca cggcgcccgc gggcacgatc ctgctcgacg gcggctacct gcaccgctcc
    16561 ctgcagccca cccggatcct caccgccgcg ctcgcccgcg ccgcccgccg ccccgacgcc
    16621 tgggaccgcg cccccgccac cggcctggag gccctgcgca ccgtgttcgc cgccatgatc
    16681 ggcggcggcc tgaccgccga cgacctcctg atcacctccg gcgggcagag cgccctgtcc
    16741 atgacgttcc gcgccatcgc cgcgccgggc gaccccgtcc tcgtcgagtc gcccacctac
    16801 cccggcgcga tcgccgccgc ccgcgccgcc ggcctgcgcc ccgtgcccgt ccccatggac
    16861 gccgacggcc tgcgacccga cctcctcgcc gacgcgttcg ccctgacccg cgcccgcctc
    16921 ctctactgcc agcccaccta ccacaacccc accggcgccg tcctcgcgcc ggaccgccgc
    16981 ccgcaggtca tcgacgccgc ccgggcggcc ggcgcgttcg tcatcgagga cgacttcgcc
    17041 cgccacctcg gccacggcac ccccatgccg cgccccctcc tggccgacga ccgccacggc
    17101 accgtgatcc acctgacctc gctcaccaaa ccggcggcgc ccagcctgcg catcggcgcc
    17161 ctcgccgccc gcggccccgt catggagcgc ctgcgcgcca tccgcctcgt cgacgacttc
    17221 ttcgtcaccc gcccgctgca ggagacggcg ctcgaactcc tcagctcacc cgcctgggac
    17281 cggcacgtcc gctccctcgc ggcggccctg cgcgagcgct gcgccaccct ggccggcgcc
    17341 ctctcgcgcg agctgcccca ctggaccctc atcggcccgc ccaggggcgg gctccacctg
    17401 tgggcccgcc tcccgcacgg cgccggcact gtcgccgacg cggcgctccg gcacggcgtc
    17461 gccgtcagcg cgggcgaccg ctacttcgcc accgagctcc cggccgccta cctccgcctc
    17521 agcttcgccg ccgccgccga ccgcgacgag ctggtcgagg ccgcccaccg cctcgccgcc
    17581 gccacctcgc actgatcccg gtcacggacg gtcaccggca ccggcccgtt gtgctggcgg
    17641 gcgccgcgac cccggggagc gaccaccggg gcgtgcgggc cgtgatgagc gtgcggcggg
    17701 gaggtctgcg ttcaccgcag acctgaccgg cgctcacgga ggcagtgaag cgtcactttc
    17761 ccggcgggcg atgccggaag accctggagg ggcacgcatc gacgcaggag acgatcccgc
    17821 cgggaggatg gcgtgacgac acccgcagcc ccgaacgtcc cgttcctcga cgtcctggac
    17881 cccgcgttcg acttcgacgc cccggaggtc tacgcggcgc aggcggagag ctggtacgcc
    17941 gacagcccct tcggcctgct cgtgctccgc tacgaggagg ccagtgacct gctgcgcgac
    18001 cggcggctga cccatgacgg ccggcgctac ctggagatgc acggcatcac cagcggtccg
    18061 atccacgact ggttcgtgcc gatgatcgtc aaccatgacg gcgacgtgca ccgccgcctg
    18121 cgcggcctga tgaacaaggc gttcacggcc cgccggatca cccggttgcg gccgttcgtg
    18181 cgggagcggg ccgaggagct gaccgacggc ctggacgacg gcggcacgca cgacttcgtc
    18241 gccgagttcg ggatccggct gccgctggcg gtcatgtgcc ggctgctcgg cgtccggccc
    18301 gaggactacg acctgttcgg cacctggacg gccgacctcg gcctgatctt cagcctgtcg
    18361 ggcggcggcg acgtcgtggc ccggctggag cgcgcggtgg acggcctgaa cgactacgcc
    18421 gaccacctga tcgacgacaa gctcgtccgg ccgtccgacg atctcagctc cgacctggtg
    18481 gcggcctacc aggcgggtga cggccaggtc agccgggagg agctgcgcaa cctgctggtc
    18541 accctcgtct tcgccgccca cgacacgacc cgccaccagc tcgccaacgc catggtcgtc
    18601 ttcgcgcggc accccgagca gtgggtgctc ctggggcggc ggccggagct ggtatcccag
    18661 gccgtggagg aggtgatgcg ctggcagccg tcctcgacca gcatctaccg cttcgccgcc
    18721 gaggacttca cctacaaggg gctcgcggtc gagaagggga tgtacctcac catgtgcgtg
    18781 aaggccgcgc agcgcgaccc tcgggcgtac aaggacgccg gccggttcga catcaccgag
    18841 gtcagggagc tgccgtcgct gcagttcggc gggggcccgc accactgcct gggggcggcc
    18901 ctggcgcggg tcgaggtggg ggaggcgctg tccgtgctgg cggcgcggct ggggccgccg
    18961 tccctgatgg ggccgccggc ctggccgggg ccgctcggca tccaggggcc ggagacgctt
    19021 ccgctgcgct tcgggccggg cctcacccgt ccagaacggc cgtgagcctg gtcagtgccc
    19081 gggtgatctg ctcggtggtg aggccgagca cggtgcgctg gtagtcgtac acctcggggg
    19141 ccaggggggc gagcagcacg tccaccagcg cgtcacggcc gggcgtgccg gcggcgacga
    19201 ggagcgcgcg cacgtgggcg cgccagaacc cgtacgcgcc ggtctcgaag cgtgagcggc
    19261 ccacctcgga gccgaggacc aggtgggagt ggtcctccag caggcgcacc atggcggcgt
    19321 agaaggccgc gagccgctcg gcgggcggcg ctcccggccc gagcggcggc tcgccgcgca
    19381 gcaggcgctc ctggagggcg cgctcgtgct cgtcgagcag cgcgacggcg atcgacgccc
    19441 ggtcggggta gcggcggtag agggtgccgc ggcccactcc ggccttcttg gcgatgtcgt
    19501 ccatcgtcac gtcctgcggg gaccgctccg cgaacagcag cgcggccgcc tccaggatcc
    19561 gtgcgcggtt gcgtgcggcg tcggctctct ccatgccccc attgtatgtg gacgcaatgt
    19621 ccgcttatag tcatctggac agcgtgtcca catatctgtg ccgaggagag atcatgctgc
    19681 ttcacctgga cgccagcgcc cgccgccacg cgtcgttctc gcggaaactg tcgagcgtgt
    19741 acgccgagac ctggcgggcc gcccaccccg acgcccgcta cgtctaccgc gacctggccg
    19801 cgcaccccgt gccgcacatc ggcgaagcct ggaccgagct gtgcgaccac atcctggagc
    19861 acgagatcac cgacatctcg cgctaccggg aggcggcccg cacccccgcc cagcaggccg
    19921 cgtgggccgt cgtggagccg ctgctcgacg aggtggtcgc ggcggacgtc atcctcatcg
    19981 gcacgccgat gtacaactac tcgatcccct cgacgctcaa ggcgtggctc gaccagatca
    20041 cgttccccaa gatgtcgctc gaaggccgct cgttcgtggt gaccagcgcg cgcggcggcg
    20101 cgtacggccc cggcacgccc cgcgagccgt acgaccacca ggagcgctac ctgcgcgact
    20161 tcttcaaggg ccacttccgc gtggaggacg tgaccttcat ccacgccgag ctggtcaacg
    20221 cccgcctcga cccggccctg gcccacctgc gcgagcagca cgagcagtcg ctggccgcgg
    20281 cgctcaagga ggcggcgcag tgagctggct gaccctgctg ctggccgggc tcgtcgaggt
    20341 ggcctggtcg cagagcatca aaccgacgca gaacttcacc cgcccgctgc ccacgctcgt
    20401 ctccctggcc ctgatggccg tcgccgtctg gctcctgtcg cgggccatga acacgctgcc
    20461 ggtcggcacc gcgtacgccg tcttcaccgg catcggcgcg gtcggcgcga tcacgctggg
    20521 catcgtggtc aacgacgacc ccgtctcggt gggcaggatg gcggcgctcg cgctgatcgt
    20581 cggcggcatc gtgctggcca ggatcaccac ctgagcccgg agagcgcgcc cgccgcggcc
    20641 cgggcgcgcc ctggccggac gctcgcacag gctttggccg cacgtccgca gggctttgcc
    20701 ggacgttgag gtaaggcgcg ggggcgctgg gcaggcgcgg gtggtgtgcc gccggcggcg
    20761 gcacctcagc ggtccccgcc ggcttccatc accagcgcgc cccggcccga gccggaggcg
    20821 gacagaaggg aagccgtgat gaccactgcg acggctgccg catccggcca gttcatgatc
    20881 gaggacgtcc tgcccgtcaa ccgcctcggc tacgggacca tgcagctcac cggccccggc
    20941 gtgtgggggc cgccggccga tccggacgag gccgtgcggg tgctgcgccg ggcggcggag
    21001 ctcggcgtca ccctcttcga caccgccgac tcctacggcc cgtgggtcgc cgagccgctg
    21061 ctgcgccgcg ctctcgcccc gtacggcgag gacatcgtga tcgccaccaa ggccggcctc
    21121 acccggcagg gccccgacca gtggacgcct gtcggccggc ccgcctacct gcgccagcag
    21181 tgcgagatga gcctgcgcaa cctcggcctc gaccggatcc cgctgttcca gctgcaccgc
    21241 gtcgacccgg acgtgccggt cgaggaccag gtcggcgagc tgcgggcgct gaaggacgaa
    21301 gggaagatcg cgcacatcgg cctgtcggag gtgagcgtcg agcagatcga gcaggcccgc
    21361 gccgtcgccc cgatcgcgtc ggtgcagaac ctgtacaacc tggccgaccg ctcggccgag
    21421 agcgtgctcg accactgcga gcggcaccgg atcgcctt
//
