LOCUS       NZ_CP017717            13217 bp    DNA     circular CON 03-MAR-2024
DEFINITION  [Actinomadura] parvosata subsp. kistnae strain ATCC 55076
            chromosome, complete genome.
ACCESSION   NZ_CP017717
VERSION     NZ_CP017717.1
KEYWORDS    RefSeq.
SOURCE      [Actinomadura] parvosata subsp. kistnae
  ORGANISM  [Actinomadura] parvosata subsp. kistnae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 13047416)
  AUTHORS   Nazari,B., Forneris,C.C., Gibson,M.I., Moon,K., Schramma,K.R. and
            Setedsayamdost,M.R.
  TITLE     Nonomuraea sp. ATCC 55076 harbors the largest actinomycete
            chromosome to date and the kistamicin biosynthetic gene cluster
  JOURNAL   Medchemcomm (2017) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13047416)
  AUTHORS   Nazari,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) Chemistry, Princeton University, 20
            Washington Road, Princeton, NJ 08544, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUN-2015
            Assembly Method                   :: Celera Assembler v. Jun 2015
            Assembly Name                     :: SmrtPipe 1.87.139483
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 13:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 12,000
            CDSs (total)                      :: 11,919
            Genes (coding)                    :: 11,783
            CDSs (with protein)               :: 11,783
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 36 of 136
            Pseudo Genes (incomplete)         :: 98 of 136
            Pseudo Genes (internal stop)      :: 10 of 136
            Pseudo Genes (multiple problems)  :: 6 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:57:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1233726
            Orig. end                         :: 1246943
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017717.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..13217
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="5"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13217
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13217
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8217](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8217
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    complement(46..66)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.1"
                     /tool="antismash"
     misc_feature    complement(392..406)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.44"
                     /tool="antismash"
     misc_feature    complement(900..915)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.11"
                     /tool="antismash"
     misc_feature    complement(1011..1026)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.1"
                     /tool="antismash"
     misc_feature    1034..1047
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.89"
                     /tool="antismash"
     gene            1187..2131
                     /locus_tag="BKM31_RS05545"
                     /old_locus_tag="BKM31_05535"
     CDS             1187..2131
                     /EC_number="2.5.1.141"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008495 - protoheme IX farnesyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0048034 - heme O biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544786.1"
                     /locus_tag="BKM31_RS05545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05535"
                     /product="heme o synthase"
                     /protein_id="WP_080037087.1"
                     /sec_met_domain="ubiA (E-value: 3.1e-14, bitscore: 52.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLTNRQATAPSQQVKAPRSIGMIVKAYIALTKPRVIELLLITT
                     LPVMFLAAGGLPPLWESIWVMVFGTLSAGSANALNCYIDRDIDQKMRRTRRRPLARHQV
                     SPRAALVFGLVLGVVSTVGLWVTTNWLASMLSLGAILFYVLVYSLVLKRRTAQNIVWGG
                     IAGCMPVMIGWAGITERLDWAPLVLFGVVFFWTPPHTWTLAMRYKEDYAAAKVPMLPVV
                     ATERRVIVESIIYTWATVLCSLALWPVAGTTLFYPIVAAVLGVMCLVEAHRLLGRLNAG
                     KSGVDLRPMRFFHWSNAYLALLFLAVAIDPLLA"
     gene            2253..3443
                     /locus_tag="BKM31_RS05550"
                     /old_locus_tag="BKM31_05540"
     CDS             2253..3443
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544787.1"
                     /locus_tag="BKM31_RS05550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05540"
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="WP_080037088.1"
                     /transl_table=11
                     /translation="MATRDPRWVLKDRPSFALIIGLVLTGICALVSFSFDVFNGAPVQF
                     FIALMLALAPVPLLLAAVLALDRMEPEPRSNLIFAFAWGAGIAVLVAGVINSLNLHYII
                     DTAKLSEASARNLAATFGAPVVEETMKGLVLLGLLRFRRAELDGPTDGVIYASMVGLGF
                     AMSENVSYYLGALSTSGVKGLAVTVVLRGILSPLAHPLFSSMIGVAVAYAAQRQGPERS
                     TYVLAGWTAAMILHGLWNGLASYGGFPGLVVAYLALLVVLVVLIGVVFRDRRRIVALIQ
                     RYLPAYEPTKLVTQADIYMLSAFSRRRQARQWARAHGGKPGLRAMRDYQLAATELGLLH
                     ERAARHMVDEHTFHEEQRALLECMSTARADFPVPEVHARSVARGSPPPGYAPGAPG"
     gene            complement(3419..3874)
                     /locus_tag="BKM31_RS05555"
                     /old_locus_tag="BKM31_05545"
     CDS             complement(3419..3874)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014724.4"
                     /locus_tag="BKM31_RS05555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05545"
                     /product="ElyC/SanA/YdcF family protein"
                     /protein_id="WP_230466011.1"
                     /transl_table=11
                     /translation="MSATPRPRRGVLSGDNSRREYDEPTAMRDHLRAKGVPDAVMVLDY
                     AGFDTWDSCVRARQVFGARRVTVVTQDFHIPRAVTLCRTAGLEAFGAGDDSARRWAVTT
                     YASAARELLATAKAFADAMILHSEPVFPGPREVSLERVLAQPGAPGA"
     gene            complement(3901..4887)
                     /locus_tag="BKM31_RS05560"
                     /old_locus_tag="BKM31_05550"
     CDS             complement(3901..4887)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0016653 - oxidoreductase activity, acting
                     on NAD(P)H, heme protein as acceptor [Evidence IEA]"
                     /GO_process="GO:0006784 - heme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544789.1"
                     /locus_tag="BKM31_RS05560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05550"
                     /product="COX15/CtaA family protein"
                     /protein_id="WP_080037089.1"
                     /transl_table=11
                     /translation="MKLPTDTSNPAVRFIRSFWAPTTRSMRGWALASVVVNAGITVTGA
                     GVRVTESGLGCPTWPRCTPDSFIPVMHPEVSPLNMAVEFGNRLLTFLVLAVGIACWLAA
                     VRMRPRRASLVRLAWLQPIGIIAQALWGGLVVNTMLNPFTVGMHYLISSGLIAACWMLY
                     ARAGEGDGPARLITHRDVRRLGHALLAAVFALLVIGVGVSGTGPHSGDEMASRFDLDIE
                     AVARLHADIAYVVVGLTFALLFALHVTGAPRAARRAALALLGVELLQGAIGYTQWFLAV
                     PAALVLLHVLGSTLVWIAALRVTTSLRSRDPESSSVSPSPTEAAAVV"
     misc_feature    complement(4972..4988)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.34"
                     /tool="antismash"
     gene            5001..6149
                     /locus_tag="BKM31_RS05565"
                     /old_locus_tag="BKM31_05555"
     CDS             5001..6149
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547415.1"
                     /locus_tag="BKM31_RS05565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05555"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_080037090.1"
                     /sec_met_domain="DAO (E-value: 3.8e-67, bitscore: 226.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDVIVVGAGVVGAACAYYAARAGLDVTVIDRGPVAGGTTGSGEG
                     NVLVSDKEPGPELELAVLSNRLWRSLAELGGFEFEPKGGLVVAETEEVQRQLTELAGKQ
                     GVEHTLVPAQELRSFEPHLAEGLAGGVYYPQDAQVQPMLAAATLLRHGADSFGHGTLRL
                     RLGATVTGFLRSGDRVTGVRTTQGDVLGDAVVNAAGTWGGEVAALAGAHLPVLPRRGFI
                     LVTEPLREPLIRHKVYTAAYVTNVASDSAGLETSAVVEGTPAGTVLIGASRERVGFDRT
                     TSVPVLARLAEQAVALFPALRDVRAIRSYCGFRPYCPDHLPVIGADPRVPGLYHACGHE
                     GAGIGLAPATGHLLAQLLAGERPDLDLHPFRPDRFPAAEEAA"
     gene            6146..6388
                     /locus_tag="BKM31_RS05570"
                     /old_locus_tag="BKM31_05560"
     CDS             6146..6388
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620515.1"
                     /locus_tag="BKM31_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05560"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_080037091.1"
                     /sec_met_domain="Fer2_4 (E-value: 7e-23, bitscore: 79.9,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFHITVDGRPVPVVPGQTIGAALHAAGVRSWRTTRFGGRPRGLF
                     CGIGVCFDCLISVNGRPPERACLLEAEPGDEVSTA"
     gene            6448..8217
                     /locus_tag="BKM31_RS62015"
                     /old_locus_tag="BKM31_05565"
     CDS             6448..8217
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF019604.4"
                     /locus_tag="BKM31_RS62015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05565"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_230466012.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.7e-18, bitscore:
                     64.9, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 8.5e-06, bitscore:
                     25.5, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGGGPAGVAGALTAALAGLRVALVDSGPRLGGQYFRHPAVPGRA
                     AGLDRFLRQARALDARADVLLRHQVWAASREPDGDLLIHCATRHAAAPTRYAATPTPNP
                     SATLRDAGAMRRDGGAMREQAGATHRDAAAAAGGAAGAGREERAVVLRARRLLIATGAH
                     DRPLPFPGWDLPGVLTAGGAQALLKGGGVVAGRRIVVSGTGPFLLPVASGLAGAGARVL
                     GVYEANGGLGLARHPLLALGKAGEVAGYAAALARHRVPYRTRQAVVAAHGEREVEAVTV
                     ARLDRDWNVTATHVVECDTLAVGYGFVPQIELGTQLGCQTRHDVDGSPVLTVDATLRTT
                     VPGVWAAGEPVGVGGWRLAELEGRLAGRAIAADARTAGIHGTARTFRTAGTAATSGIAS
                     TADTSGIASTADTSGIASTADTSGIAGALPTVDAEPSGAPATSGVPATGADVGGARAAG
                     AGVGGGGVVAVVPPVFARRRERWRAFGEALQRAYPVKPGWQGWLRDDTLVCRCEEVPLA
                     RVREAQALGATDARSVKLLARPGMGWCQGRICGYAVSCLAGEQPQPPRRPIAQPVTLGA
                     LASLAAPDDHPAH"
     gene            8246..9139
                     /locus_tag="BKM31_RS05580"
                     /old_locus_tag="BKM31_05570"
     CDS             8246..9139
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892474.1"
                     /locus_tag="BKM31_RS05580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05570"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_080037093.1"
                     /transl_table=11
                     /translation="MDHRSKPWQGVMVATALPLREDLSVDYDGYAEHCRWLVANGCDGV
                     VPNGSLGEYQTLTPQERTRVIETAVEAVGGANVMAGAGAYGAAESRRWAEQAREAGCGS
                     VLLLPPNSYRADERAVVEHYREVAKAGLPVVAYNNPYDTKVDLTPALLARLHEEGLIVA
                     VKEFSGDVRRAYELAELAPGLDLLVGSDDVLLELAVAGAVGWIAGYPNALPASNSALYR
                     AAVAGDLETALPLYRTLHPLLRWDSKTEFVQAIKLSMDVAGRHGGPCRPPRQPLTGEQA
                     AIVRAATEKALAEGLR"
     gene            9136..10137
                     /locus_tag="BKM31_RS05585"
                     /old_locus_tag="BKM31_05575"
     CDS             9136..10137
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="BKM31_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05575"
                     /product="proline racemase family protein"
                     /protein_id="WP_080037094.1"
                     /transl_table=11
                     /translation="MRTKRVFHAVDSHTEGMPTRVITGGIGVIPGASMAERRVYFRDHL
                     DHIRTLLMTEPRGHSAMSGAILQPPTRPDADYGVLFIEVSGLLPMCGHGTIGVATVLVE
                     TGMVEVVEPVTTVRLEVPAGLVEVDVAVEDGMARSVTLRNVPSYCDRLDAKVSVPGFGE
                     IPYDLAYGGNFYAIVNLDHYGLPFDRKAKNEIIAAGLATMEAINAADEPVHREDSRIRG
                     CHHVYFAAPGSDARHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLGQDFTNES
                     FIGTHFVGRLLEETTVGGRPAVLPSITGRAWITGTAQYFLDPRDPFPAGFEL"
     gene            10137..11099
                     /locus_tag="BKM31_RS05590"
                     /old_locus_tag="BKM31_05580"
     CDS             10137..11099
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544792.1"
                     /locus_tag="BKM31_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05580"
                     /product="proline racemase family protein"
                     /protein_id="WP_080037095.1"
                     /transl_table=11
                     /translation="MLTTVDYHTAGEPFRVVTGGVPDIPGATVLDRRTAAMAELDGVRR
                     LLCNEPRGHADMYGCFLVPPDDPGARFGALFWHKDGFSTACGHGTIALGVHAVREGLVE
                     AAPDGVTDVVIDVPSGRVTARVRLAGGRIEGVTFVNVPSFVLARDVPVAGVRADLSYGG
                     AVYASVRAADLGLAVEPAHVNAFIGHARRIKAELAGHPAARHPSDERLSGVYGVIFHDD
                     LPDVDGVRRQRNVTVFADGEVDRSPCGSGTAARMALLHEDKVMQLVHEGIVGGVFTARV
                     REETDAGVIVEVDGMAYRTGRHVFELDPGDPFPAGFTLR"
     gene            11108..12100
                     /locus_tag="BKM31_RS05595"
                     /old_locus_tag="BKM31_05585"
     CDS             11108..12100
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544793.1"
                     /locus_tag="BKM31_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05585"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_230466013.1"
                     /transl_table=11
                     /translation="MSGAMSGAMSGLAYFDAATVERLVPMGRAVTVLEEALRAGLDPEA
                     TPRRPIVDLPAGQLLLMPAATRSYAGVKAVTIAPGNATRGLPRIQGTYLLFDGETLAPL
                     AAMDGIALTSLRTPAVSALAVRHLAEPDARRLVVFGSGPQAYGHVLALREVRPVRDVTV
                     VARDPGRAEALAARCRDLGLTARALPAGQPEAGTAEQPAAFAEAVAAADLIACCTTARH
                     PLFPGKLARDGVTVVAVGSHEPDARELDGDLVAHATVVVESRASALEEAGDVIVPIRQG
                     TITSHHLAGNLADLIAGRVGAGPGPRVFKSTGMAWEDLVVAAAAYEART"
     gene            12127..12795
                     /locus_tag="BKM31_RS05600"
                     /old_locus_tag="BKM31_05590"
     CDS             12127..12795
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544794.1"
                     /locus_tag="BKM31_RS05600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_05590"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_080037097.1"
                     /transl_table=11
                     /translation="MAAEDRLDLPMVGERQSLREQVAHALRAALITGEMRPGVVYSAPV
                     LAAQFGVSATPVREAMLDLAKEGLVEAVRNKGFRVTELSDRDLDELTEIRQLIEVPTVA
                     RLADSARAEEFERLRPIAEEIVSASERGDLLAYVDADLRFHVELLSLCGNAHLVSVVRD
                     LRNRARLYGLSQLSERGTLGDSAREHLQLLDALKSGDGAAVGHLMAEHIGHVRGIWAEH
                     "
ORIGIN
        1 ttccttggtg gcggccacct cggcctcgcc cagggcggag ccgtggatct tgccggtgtt
       61 ctgcttgttg ggggcggggt agccgatgat cgtgcgcagc cggatgaacg acggccggtc
      121 ggtctccgcc cgggcggcct ggagggcgtc gtagagggcc tggacgtcct cgacgtactc
      181 gccggtggcg gtccagtcga cgctctgcgt gtgccagccg taggcctcgt agcgcttgac
      241 cacgtcctcc gacagggcga tctgcgtgtc gtcctcgatg gagatgtggt tgtcgtcgta
      301 gacgacgacg aggttgccca gcttctggtg gccggcgagg gagctggcct cgtggctgat
      361 gccctcctcg atgtcgccgt cgctgacgaa gcaccagatg ttgtggtcga acggcgaggt
      421 gcccggctcg gcctcggggt cgaacaggcc gcgctcgcgg cgggcggcca tggccatgcc
      481 gaccgcgttg gcgatgccct ggcccagcgg gccggtggtg gtctccacgc ccgcggtgtg
      541 gccgtgctcg gggtggcccg gcgtcaggct gtcccactgg cgcagccgct tcaggtcgtc
      601 cagcgtcagg ccgtagcccg acaggtagag ctggatgtag agcgtcaggc tgctgtggcc
      661 gcacgacagc acgaaacggt cgcgtccgag ccagttgggg tcggtcgggt catggcgcat
      721 cacacgctgg aacagcaggt atgcggcggg ggccagactc atggcggtgc cggggtgacc
      781 cgagcccgcc ttctccacgg cgtccatggc cagggctcga acgacgtcga ccgccttctt
      841 gtcgaggtcg gtccattcaa gggctggcac gagttcggtg ctcaagtgct cgatctccgg
      901 aatctagttg tcattggata cggctgtccc gcccgggccg gccgcgggcg gcggcctgcc
      961 gcaggttgcg ctgcccgcgc catacaccgg accataaccg aggggtgccg gtgatcgatt
     1021 cccattacac cctcgtgtgt ccatgcacgg cgcaaagccc cccattggcc ggaccggcct
     1081 cccctgcgac tacagtttgt ttgttcgcag gggcgtcacc ggcgcccgcc catggatccg
     1141 ctcttatcag aggttacgcg ttgacttccg acaggctgga agcgccttga cggtgctgac
     1201 caacaggcag gcgacggccc catcacagca ggtgaaggcg ccgcgctcga tcggcatgat
     1261 cgtcaaggcc tacatcgcgc tcaccaagcc gcgggtcatc gagctgctgc tgatcacgac
     1321 actgccggtg atgttcctcg cagcgggcgg cctgccgccg ctgtgggagt cgatctgggt
     1381 catggtgttc ggcaccctat cggcaggaag cgccaacgcg ctcaactgct acatagaccg
     1441 cgacatcgac cagaagatgc gccgcacccg ccgccggccc ctggcccggc accaggtctc
     1501 gccgcgcgcc gcgctcgtct tcgggctcgt gctgggcgtc gtctccacgg tgggcctgtg
     1561 ggtgaccacc aactggctgg cctcgatgct gtcgctcggc gccatcctgt tctacgtcct
     1621 ggtctactcg ctggtgctca agcggcgcac cgcccagaac atcgtgtggg gcggcatcgc
     1681 gggctgcatg ccggtcatga tcggctgggc cggcatcacc gagcggctcg actgggcgcc
     1741 gctggtgctg ttcggggtgg tgttcttctg gacgcccccg cacacctgga cgctggccat
     1801 gcgctacaag gaggactacg cggcggccaa ggtgccgatg ctgcccgtgg tcgccaccga
     1861 gcggcgggtc atcgtcgagt cgatcatcta cacgtgggcc accgtgctgt gctcgctggc
     1921 gctgtggccg gtggccggca ccacgctgtt ctacccgatc gtggcggccg tgctgggcgt
     1981 gatgtgcctg gtcgaggcgc accgcctgct cgggcggctg aacgccggca agagcggcgt
     2041 cgacctgcgg ccgatgcggt tcttccactg gtccaacgcc tacctggcgc tgctgttcct
     2101 ggcggtggcg atcgacccgc tgctcgcctg acccgcggtg ggagtcccgc cgggctcccc
     2161 gcccccggcc tcatgtctgg acggtgacga gtggctatcc gacgccgcag gtccgcacgg
     2221 cccccggcac cctgatccgt taaagtcacc ctatggcgac ccgtgatcca cgctgggtgt
     2281 tgaaggaccg cccgtcgttc gcgttgatca tcgggctggt cctcaccggc atctgcgccc
     2341 tggtctcgtt ctccttcgac gtcttcaacg gcgcgccggt gcagttcttc atcgccctca
     2401 tgctggcgct ggccccggtg ccgctgctgc tggcggccgt gctggcgctc gaccgcatgg
     2461 agcccgagcc gcgcagcaac ctcatcttcg ccttcgcctg gggcgccggc atcgccgtgc
     2521 tcgtggccgg cgtgatcaac tccctcaacc tgcactacat catcgacacc gccaagctgt
     2581 cggaggccag cgcccgcaac ctcgcggcca ccttcggcgc gcccgtggtg gaggagacga
     2641 tgaagggcct ggtgctgctg ggcctgctca ggttccgccg ggccgagctc gacgggccca
     2701 ccgacggcgt catctacgcc agcatggtcg gcctcggctt cgccatgagc gagaacgtca
     2761 gctactacct cggcgcgctg tccacctccg gcgtcaaggg cctggccgtc acggtggtgc
     2821 tgcgcggcat cctgtcgccg ctggcgcacc ccctgttcag ctccatgatc ggggtcgccg
     2881 tcgcgtacgc ggcgcagcgg caggggcccg agcgcagcac gtacgtgctg gccggctgga
     2941 cggccgcgat gatcctgcac gggctgtgga acggcctggc ctcctacggc gggttccccg
     3001 ggctcgtggt cgcctacctg gcgctgctgg tcgtgctggt ggtgctgatc ggcgtggtgt
     3061 tccgcgaccg gcgccggatc gtggcgctca tccagcgcta cctgccggcg tacgagccga
     3121 ccaagctggt cacccaggcc gacatctaca tgctctcggc cttctcccgg cgccgccagg
     3181 cccggcagtg ggcccgcgcc cacggcggca agccggggct gcgggccatg cgcgactacc
     3241 agctcgccgc caccgagctg ggcctgctgc acgaacgggc ggcccggcac atggtcgacg
     3301 agcacacctt ccacgaggag cagcgggcgc tgctggagtg catgagcacc gcccgcgccg
     3361 acttcccggt gccggaggtg cacgcccgct cggtggccag gggctcaccg ccgcccggct
     3421 acgcgcccgg cgcgcccggc tgagccagga cgcgttccag ggagacctcg cgcgggccgg
     3481 ggaagaccgg ctcggagtgc aggatcatcg cgtcggcgaa ggccttggcg gtggcgagca
     3541 gctcgcgggc ggcgctcgcg tacgtggtca cggcccagcg cctggccgag tcgtcgcccg
     3601 ccccgaacgc ctccagcccc gccgtcctgc acagcgtgac cgcccgtggg atgtggaagt
     3661 cctgggtgac caccgtcacc cgccgcgccc cgaacacctg gcgggcccgc acgcacgagt
     3721 cccacgtgtc gaagccggcg tagtcgagca ccatcacggc gtcgggcacg cccttggcgc
     3781 gcaggtggtc gcgcatggcg gtgggctcgt cgtactcgcg gcggctgttg tcgcccgaca
     3841 gcacacccct tctgggccgg ggagtggcgg acacgacacc acataccctg gcatatccgc
     3901 tcagacgacg gcggccgctt cggtggggga ggggctgacg gaagaagact cggggtcacg
     3961 ggaccgcagc gaggtggtga cccgcagcgc ggcgatccac accagcgtcg agccgagcac
     4021 gtgcagcagc accagcgccg ccggcacggc caggaaccac tgcgtgtagc cgatggcgcc
     4081 ctgcagcagc tccacgccga gcagcgccag cgccgcccgc ctggccgccc ggggcgcccc
     4141 ggtcacgtgc agggcgaaca gcagcgcgaa cgtcagcccg accacgacgt aggcgatgtc
     4201 ggcgtgcagc cgggccaccg cctcgatgtc gaggtcgaag cgcgaggcca tctcgtcgcc
     4261 cgagtgcggc ccggtgccgc tgacgccgac gccgatcacc agcagcgcga acacggccgc
     4321 cagcagcgcg tgcccgagcc tgcggacgtc gcggtgggtg atcagccggg ccgggccgtc
     4381 gccctcgccg gcgcgggcgt acaacatcca gcaggccgcg atcaggccgc tggagatcag
     4441 gtagtgcatg ccgacggtga acgggttgag catggtgttg accaccagcc cgccccacag
     4501 ggcctgcgcg atgatgccga tcggctgcag ccaggccagg cgcaccagcg aggcgcggcg
     4561 cggccgcatc cgcacggcgg ccagccagca ggcgatgccc accgccagca ccaggaacgt
     4621 cagcagccgg ttgccgaact cgaccgccat gttgagcggc gagacctcgg ggtgcatgac
     4681 cgggatgaag ctgtcgggcg tgcacctcgg ccaggtcggg cagcccagcc cggactcggt
     4741 gacgcgcacg cccgcgccgg tgaccgtgat gcccgcgttg accaccacgg acgccaacgc
     4801 ccagccgcgc atcgagcgcg tggtcggcgc ccagaaggac cggatgaacc gcacggcggg
     4861 gttggaggtg tcggtgggta gcttcacgtc atcgatggta ggggccgatg tggccggtcc
     4921 cgccaccggg aaccggcttg tcctgccccg ggcttctcaa gcccgcaagg tatgtgacat
     4981 attactgata ggaggtggtg atgtccgacg tgatcgtcgt cggcgcggga gtggtggggg
     5041 cggcctgcgc ctactacgcc gcgcgggccg gcctcgacgt gaccgtgatc gaccgggggc
     5101 ccgtggccgg tggcacgacg ggctcgggcg agggcaacgt cctggtctcc gacaaggagc
     5161 cggggcccga gctggagctg gccgtgctgt ccaaccggct gtggcgctcg ctggccgaac
     5221 tgggcgggtt cgagttcgag cccaagggcg ggctcgtcgt cgccgagacc gaagaggtcc
     5281 agcggcagct caccgagctg gccggcaagc agggcgtcga gcacaccctc gtcccggccc
     5341 aggagctgcg ctccttcgag ccgcacctcg ccgagggcct ggccggcggc gtgtactacc
     5401 cgcaggacgc ccaggtgcag cccatgctcg ccgccgccac cctgctgcgg cacggcgccg
     5461 acagcttcgg ccacggcacg ctgcggctgc ggctcggcgc caccgtcacc ggcttcctgc
     5521 gctcagggga ccgggtgacg ggcgtgcgca ccacgcaggg cgacgtgctc ggcgacgccg
     5581 tcgtcaacgc ggccggcacc tggggcggcg aggtcgccgc cctggccggc gcccacctgc
     5641 cggtgctgcc ccgacgcggc ttcatcctcg tcaccgagcc cctgcgcgag ccgctcatcc
     5701 ggcacaaggt ctacaccgcc gcctacgtca ccaacgtggc cagcgactcc gccggcctgg
     5761 agacctccgc cgtcgtcgag ggcacccccg ccgggaccgt gctcatcggg gccagcaggg
     5821 aacgcgtcgg gttcgaccgg acgacgtccg tgccggtgct ggcacggctg gccgagcagg
     5881 cggtcgcgct cttccccgcg ctgcgcgacg tgcgggccat ccggtcctac tgcgggttcc
     5941 ggccgtactg ccccgaccac ctgcccgtca tcggcgccga cccgcgcgtg ccgggcctct
     6001 accacgcgtg cggccacgaa ggggccggca tcgggctcgc gcccgccacc gggcacctgc
     6061 tcgcccagct cctcgccggc gagcggcccg acctcgacct gcaccccttc cgccccgacc
     6121 gcttccccgc cgccgaggag gccgcatgac cttccacatc accgtcgacg gccggcccgt
     6181 gccggtcgtg cccggccaga cgatcggcgc ggccctgcac gccgccgggg tccggtcgtg
     6241 gcgcaccacc cgcttcggcg ggcggccgcg cgggctgttc tgcggcatcg gggtctgctt
     6301 cgactgcctg atctccgtca acgggcggcc gcccgagcgg gcgtgcctcc tggaggccga
     6361 gccaggggac gaggtgagca cggcatgacg tccggagcca tgcctcacga cagcgggccc
     6421 cacggccccg agccttacga tcttgtggtg gtcggcggtg ggcccgccgg cgtggcgggc
     6481 gcgctcacgg cggcgctggc cgggctgcgg gtggccctcg tggactccgg gccgaggctc
     6541 ggcggccagt acttccgcca ccccgccgtg cctgggcgcg cggccgggct cgaccggttc
     6601 ctgcggcagg cgcgggccct cgacgcgcgc gccgacgtgc tgctgcggca ccaggtgtgg
     6661 gccgcgtccc gcgagccgga cggcgacctc ctgatccact gcgccacccg gcacgccgcc
     6721 gccccgaccc ggtacgccgc caccccgacc ccgaacccga gcgcgacgct ccgcgacgca
     6781 ggcgcgatgc gccgggacgg cggtgcgatg cgcgagcagg ccggcgcgac ccacagggac
     6841 gccgctgcgg cggccggagg tgccgctggg gcgggccggg aggagcgggc ggtggtgctg
     6901 cgggcgcggc ggctgctgat cgcgaccggc gcgcacgacc ggccgctgcc gttccccggg
     6961 tgggacctgc ccggggtgct caccgccggc ggcgcgcagg cgctgctcaa gggcggcggc
     7021 gtcgtcgccg ggcggcggat cgtcgtgtcc ggcaccgggc cgttcctgct gcccgtcgcc
     7081 tccgggctgg ccggggcggg cgcgcgggtg ctcggcgtgt acgaggcgaa cggcggtctc
     7141 gggctggccc ggcacccgct gctggccctg ggcaaggccg gggaggtggc cgggtacgcg
     7201 gcggcgctgg cccggcaccg ggtcccgtac cggacgcgcc aggcggtcgt cgccgcccac
     7261 ggggagcgcg aggtggaggc cgtcaccgtc gcccgcctcg accgggactg gaacgtgacc
     7321 gccacgcacg tcgtcgagtg cgacaccctc gccgtggggt acggcttcgt gccgcagatc
     7381 gagctgggca cccagctcgg ctgccagacc cgccacgacg tggacggcag ccccgtgctc
     7441 accgtggacg ccacgctccg caccaccgtg ccgggggtgt gggcggcggg cgagcccgtc
     7501 ggcgtgggcg gctggcgcct ggccgaactc gagggccgcc tcgccggccg cgccatcgcc
     7561 gccgacgccc gcaccgccgg catccacggc accgctcgca ccttccgcac tgccggcacc
     7621 gccgcgacct cgggcatcgc gagcaccgcc gacacctcgg gcatcgcgag caccgccgac
     7681 acctcgggca tcgcgagcac cgccgacacc tccggaatcg ccggcgcgct ccccaccgtc
     7741 gacgccgagc cgagcggcgc gcccgcgacc agcggtgtgc ccgcgacggg cgccgacgtc
     7801 ggtggtgcgc gcgcggccgg tgccggagtg ggcggcggag gggtggtggc ggtcgtgccg
     7861 ccggtgttcg cgcgcaggcg ggagcggtgg cgggcgttcg gggaggcgct gcagcgcgcg
     7921 taccctgtca agcccggctg gcaggggtgg ctgcgggacg acacgctcgt gtgcaggtgc
     7981 gaggaggtgc cgctggcccg ggtacgtgag gcgcaggcgc tcggcgccac cgacgcgcgc
     8041 tcggtcaagc tgctggcccg ccccggcatg ggctggtgcc agggccgcat ctgcggttac
     8101 gccgtgtcct gcctggcagg ggagcagccc cagccgcctc gccgcccgat cgcccagccc
     8161 gtgaccctcg gcgccctggc ctcgctcgcc gcccccgacg accatcccgc tcactgaacc
     8221 ccccgcacac ctggaggaca tccccatgga tcaccgcagc aagccctggc agggcgtcat
     8281 ggtcgccacc gcgctgcccc tgcgcgagga cctgtcggtc gactacgacg gctacgcgga
     8341 gcactgccgc tggctggtcg cgaacggctg tgacggcgtc gtgccgaacg gctcgctcgg
     8401 cgagtaccag acgctcaccc cgcaggagcg caccagggtg atcgagacgg ccgtcgaggc
     8461 cgtgggcggc gcgaacgtga tggcgggggc gggcgcgtac ggcgccgcgg agtcgcgccg
     8521 ctgggcggag caggcgcgcg aggcgggctg cggctcggtg ctgctgctgc cgccgaactc
     8581 ctaccgggcc gacgagcggg ccgtcgtgga gcactatcgc gaggtggcca aggcgggcct
     8641 gccggtggtg gcctacaaca acccctacga cacgaaggtg gacctgactc ccgcgctgct
     8701 ggccaggctg cacgaggagg ggctgatcgt ggcggtcaag gagttcagcg gcgacgtgcg
     8761 cagggcgtac gagctggcgg agctggcacc gggcctggac ctgctggtcg gctccgacga
     8821 cgtgctgctg gagctggccg tggccggcgc ggtgggctgg atcgccggct acccgaacgc
     8881 gttgcccgcc tccaactccg ccctctaccg tgccgccgtg gcgggcgacc tggagacggc
     8941 gctgccgctg taccggaccc tgcatccgct gctgcgctgg gactccaaga cggagttcgt
     9001 tcaggcgatc aagctgtcca tggacgtggc gggacgccac ggcggcccgt gcaggccgcc
     9061 caggcagccc ctgaccggcg agcaggcggc tattgtgcgt gcggcgaccg agaaggcact
     9121 ggcggaaggg ctgcgatgag gaccaagcgc gttttccacg ccgtcgactc ccacaccgag
     9181 ggcatgccca cccgggtcat cacgggcggc atcggcgtga tccccggcgc gagcatggcg
     9241 gagcggcgcg tctacttccg cgaccacctc gaccacatcc gcacgctgct gatgacggag
     9301 ccgcgcggcc actcggccat gagcggcgcc atcctgcagc cgccgacgag gccggacgcc
     9361 gactacgggg tgctgttcat cgaggtgtcg gggctgctgc cgatgtgcgg gcacggcacg
     9421 atcggcgtgg cgacggtgct ggtcgagacc ggcatggtgg aggtggtcga gccggtcacg
     9481 accgtgcggc tggaggtgcc ggccgggctc gtcgaggtgg acgtggccgt cgaggacggc
     9541 atggccaggt cggtgacgct gcgcaacgtg ccctcgtact gtgaccggct ggacgcgaag
     9601 gtgagcgtgc cggggttcgg ggagatcccg tacgacctcg cgtacggcgg caacttctac
     9661 gccatcgtca acctcgacca ctacggcctg ccgttcgacc gcaaggccaa gaacgagatc
     9721 atcgcggccg gcctggcgac catggaggcc atcaacgccg ccgacgagcc cgtgcaccgg
     9781 gaggactccc gcatccgcgg ctgccaccac gtgtatttcg ccgcccccgg ctccgacgcc
     9841 cgccactcgc ggcacgcgat ggcgatccac ccgggctggt tcgaccgctc gccgtgcggc
     9901 accggcacca gcgcccgcat ggcgcagctg cacgccaggg gcgagctgcc gctcggccag
     9961 gacttcacga acgagtcgtt catcggcacc cacttcgtcg gccggctgct ggaggagacc
    10021 acggtgggcg ggcggccggc cgtgctgccg tcgatcaccg ggcgcgcctg gatcaccggg
    10081 accgcccagt acttcctcga cccgcgcgac ccgttcccgg ccgggttcga gctctgatgc
    10141 tgacgaccgt cgactaccac acggcggggg agccgttccg ggtcgtgacg ggcggcgtgc
    10201 ccgacattcc cggcgccacc gtgctcgacc ggcgcaccgc cgcgatggcc gagctcgacg
    10261 gcgtgcggcg gctgctgtgc aacgagccgc gcgggcacgc cgacatgtac ggctgcttcc
    10321 tcgtgccccc ggacgacccg ggggcgcgct tcggcgcgct gttctggcac aaggacggct
    10381 tctccaccgc ctgcgggcac ggcacgatcg cgctgggcgt gcacgcggtc cgcgaggggc
    10441 tggtcgaggc cgccccggac ggcgtgacgg acgtggtgat cgacgtgccg tcgggacgcg
    10501 tcacggcccg ggtgcggctg gccggaggcc ggatcgaggg cgtcacgttc gtcaacgtgc
    10561 cctcgttcgt gctggcgaga gacgtgccgg tcgcgggcgt gcgcgccgac ctctcctacg
    10621 gcggcgcggt ctacgcgtcc gtacgcgcgg cggacctcgg cctggcggtc gagcccgcgc
    10681 acgtgaacgc gttcatcggg cacgcccggc ggatcaaggc ggagctggcc gggcacccgg
    10741 cggcccggca cccgtccgac gagcggctgt ccggcgtgta cggggtgatc ttccacgacg
    10801 acctgccgga cgtggacggg gtcaggcggc agcgcaacgt caccgtgttc gccgatggcg
    10861 aggtggaccg ctcgccgtgc ggctcgggca ccgccgcgcg gatggcgctg ctgcacgagg
    10921 acaaggtgat gcagctggtc catgagggca tcgtgggcgg cgtgttcacc gcccgcgtgc
    10981 gggaggagac ggatgcgggc gtgatcgtgg aggtcgacgg catggcgtac cggaccggga
    11041 ggcacgtctt cgagctcgac cccggcgacc cgttcccggc cgggttcacc ctgagatgag
    11101 cgggtcgatg agcggggcga tgagcggggc gatgagcggg ctcgcctact tcgacgccgc
    11161 gacggtggag cggctggtgc cgatgggccg ggccgtgacc gtgctggagg aggcgctgcg
    11221 ggccgggctc gacccggagg cgacgccgcg gcggccgatc gtcgacctgc ccgccgggca
    11281 gctgctgctc atgcccgccg cgacgcgctc gtacgcgggg gtcaaggcgg tcaccatcgc
    11341 gccggggaac gcgacgcggg ggctgccccg gatccagggc acgtacctgc tgttcgacgg
    11401 tgagacgctg gcgccgctgg cggccatgga cgggatcgcg ctcacctcgc tgcgcacgcc
    11461 cgccgtctcc gcgctcgccg tccggcacct ggccgagccg gacgcgcggc ggctggtggt
    11521 gttcgggagc gggccgcagg cgtacgggca cgtgctggcg ctgcgggagg tgcggccggt
    11581 gcgggacgtc acggtcgtcg cccgcgaccc gggccgcgcc gaggcgctgg ccgcccgctg
    11641 ccgcgatctg ggcctgacgg cccgcgccct gccggccggg cagccggagg cgggaacggc
    11701 cgagcagccg gcagcgttcg cggaggccgt ggcggcggcc gatctgatcg cgtgctgcac
    11761 caccgcgagg caccccctgt tccccggtaa gctcgcccgc gacggcgtca ccgtcgtcgc
    11821 ggtcggctcg cacgagcccg acgcccgtga gctggacggc gacctggtcg cccacgccac
    11881 cgtggtcgtc gagtcgaggg cgtccgccct ggaggaggcc ggtgacgtca tcgtgccgat
    11941 ccgccagggt acgatcactt ctcatcatct cgccggtaac ctcgccgacc tgatagccgg
    12001 aagggtaggg gccggtccgg gaccgcgcgt gttcaagagc acgggtatgg cgtgggaaga
    12061 cctcgtggtc gcggccgccg cttacgaggc gcgcacatga gagcggacag agaaggggat
    12121 gggccgatgg ctgccgagga ccggctcgac ctgccgatgg tgggagagcg gcagagcctg
    12181 cgcgagcagg tcgcgcacgc gttgcgagcc gcgctgatca ccggcgagat gcggccgggg
    12241 gtggtctact ccgcgccggt gctggccgcc cagttcggcg tctcggccac gcccgtgcgc
    12301 gaggcgatgc tcgacctggc caaggagggc ctggtcgagg ccgtgcgcaa caagggcttc
    12361 cgcgtcacgg agctgtccga tcgcgacctc gacgagctga cggagatccg ccagctcatc
    12421 gaggtgccga cggtggcccg gctcgccgac agcgcgcggg cggaggagtt cgagcggttg
    12481 cggcccatcg cggaggagat cgtctcggcc agcgagcggg gcgacctgct cgcgtacgtg
    12541 gacgccgacc tgcgcttcca cgtggagctg ctgtcgctgt gcggcaacgc ccacctggtc
    12601 tcggtggtgc gcgacctgcg caacagagcc aggctctacg gcctgtcgca gctgtcggag
    12661 cgcggcacgc tgggcgactc ggccagggag cacctgcaac tgctggacgc gctcaagagc
    12721 ggcgacggag ccgccgtcgg gcacctgatg gccgagcaca tcggccacgt ccgcggcatc
    12781 tgggccgagc actgaccttc cgcgtctctg gtccgaacgt ttctggtccg gacgtttctg
    12841 ctccgaacac tgagcgcaag ttccgacatt cagggatcgg gcactcccgg atggcggtaa
    12901 tctcgatgcg gacctgccga gcgacgcctt gaggcgagcg ccggcggccc tgccatcccg
    12961 gtccgccatc ggcggatcat gcggcatcat gcctggtcaa gcggacaccc gcactccgct
    13021 gacctccatg ggctcggcac accccgccca ccgagccgag cccaccgccg cgcgcccgag
    13081 accccatccc acgggcgcgc ggcggccctc atgaccgctt gcggacgcgg gtggagccca
    13141 ggctggcggc cacgatgcag atgacggccg cccactgctg ggcgtgcagg atctcgccga
    13201 gcagcagcac cccgatc
//
