LOCUS       NZ_CP017717            32813 bp    DNA     circular CON 03-MAR-2024
DEFINITION  [Actinomadura] parvosata subsp. kistnae strain ATCC 55076
            chromosome, complete genome.
ACCESSION   NZ_CP017717
VERSION     NZ_CP017717.1
KEYWORDS    RefSeq.
SOURCE      [Actinomadura] parvosata subsp. kistnae
  ORGANISM  [Actinomadura] parvosata subsp. kistnae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 13047416)
  AUTHORS   Nazari,B., Forneris,C.C., Gibson,M.I., Moon,K., Schramma,K.R. and
            Setedsayamdost,M.R.
  TITLE     Nonomuraea sp. ATCC 55076 harbors the largest actinomycete
            chromosome to date and the kistamicin biosynthetic gene cluster
  JOURNAL   Medchemcomm (2017) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13047416)
  AUTHORS   Nazari,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) Chemistry, Princeton University, 20
            Washington Road, Princeton, NJ 08544, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUN-2015
            Assembly Method                   :: Celera Assembler v. Jun 2015
            Assembly Name                     :: SmrtPipe 1.87.139483
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 13:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 12,000
            CDSs (total)                      :: 11,919
            Genes (coding)                    :: 11,783
            CDSs (with protein)               :: 11,783
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 36 of 136
            Pseudo Genes (incomplete)         :: 98 of 136
            Pseudo Genes (internal stop)      :: 10 of 136
            Pseudo Genes (multiple problems)  :: 6 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:57:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 895663
            Orig. end                         :: 928476
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017717.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..32813
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="4"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..32813
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32813
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:22813](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..22813
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    complement(649..660)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(758..776)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.56"
                     /tool="antismash"
     gene            759..1577
                     /locus_tag="BKM31_RS04045"
                     /old_locus_tag="BKM31_04020"
     CDS             759..1577
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547228.1"
                     /locus_tag="BKM31_RS04045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04020"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_080036840.1"
                     /transl_table=11
                     /translation="MRRVLQYVALVAYVVFLAFPLLWLLSTALKTPQEMALTEPTWIPR
                     EPTLANFGDAFGEQDLVGAALRSLVVALFASVITVLISLPAAYAMARYRGLLNKVAIGW
                     VLVSQVFPFILIIIPLFMILRDLDLVNTLPGLVVVHVTFTLPFALWMLQGYVRAVPREL
                     EEAAAVDGAGRLRSIASVVAPLLAPGVVATLLFSFISSWNEFMFALVVLQNPDVMTLPL
                     TLVRFTGPEGVARLGPLAAASLMATIPSLIFFAIIQRRLKSGLMAGAVKG"
     gene            1587..2891
                     /locus_tag="BKM31_RS04050"
                     /old_locus_tag="BKM31_04025"
     CDS             1587..2891
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547227.1"
                     /locus_tag="BKM31_RS04050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04025"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_080036841.1"
                     /transl_table=11
                     /translation="MRITSALAAAAILTLAAACGGGGGGGSSSAPNEPVKINFLSLAWQ
                     KESVAANKQLVDEWNKANPNIQVTYVQGSWDNVNDQLVTQFAGGTAPDVIHNDSPALSG
                     FASDGYLLDLKDKLPAELKSDIPQSAWDTVTFDDGKGGQGVYGVPFLQESQVIIANKKL
                     LDAAKVRIPTADDPWTWDEFSEAAKKMTKDGSYGVAWAMKSPVNKTLNLALNFGGTFFQ
                     TSGGKTTVKVGPEEREVLQRIHDQLYKDKSADPDALGQGTADPLPAFYKGKFAMLPAGV
                     YLRQQVVEQAPDGFEWVTLPAPKGTSAQQGAVSQTLSIAQESEHPDEAMKFISFFLNGT
                     NQAKLAKGDWLLPTSQKAAADPAMTTEENGWDVATASAKNLVVAPFLKVNGFDEWKSKV
                     ATPALQEYFANKITIDQAAAKLVEDGNKVLERYQR"
     gene            2888..4033
                     /locus_tag="BKM31_RS04055"
     CDS             2888..4033
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015692.4"
                     /locus_tag="BKM31_RS04055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_080036842.1"
                     /transl_table=11
                     /translation="MITARERARGCLLGLAAGDALGAPAENLTPQEIRRRWGRLTEIEG
                     GGTDDTEYAIFAASLLVRHGHALTPADVAAAYRTEIIPLVTGPMRGAGFSELGTVEALR
                     RGLQPPLTGLVHSHGWSDGLAMRAAPYGIFCPGDPAEAARLVEQDGLVSGSGEGILGGR
                     AIAAAVASAMAGASPHEVVRAALSVVPADSWTARNVVRACETLGWSPPTATTGIAAATT
                     TPSTELAPARPGAGAEAPPPSGLPSAGAAGSRSVESGATRAAAGHATGDGAEVVEALHR
                     AVVVEHYPWTDIAPEAVALALAAFLAGDGDVERAVTFGVSLGRDADTIGAIAGAIAGAS
                     QGERGVPARWAARIGPVTGKCLPVVAGRHVLDVADELAGGL"
     gene            4040..5032
                     /locus_tag="BKM31_RS04060"
                     /old_locus_tag="BKM31_04035"
     CDS             4040..5032
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892654.1"
                     /locus_tag="BKM31_RS04060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04035"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_080036843.1"
                     /transl_table=11
                     /translation="MSGDRIRGAVIGLAVGDAVGWPAGRHRAALHAPWSRRLHRELDAF
                     AEEHRVTTLPVPFALNQPTAPLRVGPSDDAEWLAWTLLTADRPRAEAFRELVGTDGGAQ
                     ADARPIRGRISVMTALDNLAKGVEPPASGHDNPHHFDDAAAVRAVAYGILGRDPTPDAQ
                     VTNAGDGVPAARAMAAAIQEAVASGSAGAAVEAALAVLPPDTAIGHNARLALDVARKAG
                     DPFGAIPALDAALLDHVYSYGVGAAQTVPVALALVETAGGELARAVPAAACLAPLADSA
                     PALAGALAGACGGYEAIPEGWTASARTLAGCCLPDLAGRDLIELLEGIA"
     gene            5029..6168
                     /locus_tag="BKM31_RS04065"
                     /old_locus_tag="BKM31_04040"
     CDS             5029..6168
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547224.1"
                     /locus_tag="BKM31_RS04065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04040"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_080036844.1"
                     /transl_table=11
                     /translation="MTPLEDRATGCVAGAAVGDALGGATEGWTPEQIVQRYGGRVEGIV
                     PPFNEDWRNARPIAPYHKGDGHITDDTLMTHALIRVYAKVGGHLDAYAMAEHLVPELMG
                     ERRWIPELEAEALPLQRIFLAEKWIVARLHYGHADPREAGVGNIVNCGAAMYVAPVGIV
                     NAADPDAAYAEAIELTGAHQSSYGREAAGVMAAAVAEAMRPGATADSVVGACLRLAKDG
                     TRAAIEAVCEAAAGLGHWDGSFEALRAAVRPFDTVADTYRDQGLGARRPSRVHSIEELP
                     LALGFLVIAKGDFRDTVLGGVNYGRDADSIASMGGAIAGALGGLESVPQEWVTQVAAAS
                     RTDLVAPGLAIAAVARRVHADDLVRRRAHESAFAELERA"
     gene            6165..7505
                     /locus_tag="BKM31_RS04070"
                     /old_locus_tag="BKM31_04045"
     CDS             6165..7505
                     /EC_number="3.2.2.-"
                     /GO_function="GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547223.1"
                     /locus_tag="BKM31_RS04070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04045"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_080036845.1"
                     /transl_table=11
                     /translation="MIRLTWVQPEDLVGHELRQATEDGRDGRDVRSIAARWHAAGGHDA
                     PPRAGASEPGAARLRGLAEELLDELAAVPSPLPEPSDLPGIIAACPAWPDKSAGAGAVD
                     PERVLGAWLGRAAGCVLGKPVEKIPRAGIREIAQATGNWPIRGWFTAKGLPDDVARRWP
                     WNRRSAVNSLAENIDGIPEDDDLNYPLLALSLLERHGRGFTTEDVARLWLDELPAGRTF
                     TAERIAYRNLLDGVEPPATATYRNPFREWIGALIRADVYGWVNPGDPATAAEYAWRDAR
                     LTHTANGIYGAMFAAAMCAASMVATSAEEVVRAGLSVVPEGSRLHEAVRLAAEDAAGED
                     DFERVVDRLHERHGHLHWVHTINNAALVAATLIHGKGDFTATIAGAVAGGWDTDSAGAT
                     AGAVAGALAGGVPERWRMRDSLASSLTGFDGVGLAELAARTQEMMKP"
     gene            7502..8386
                     /gene="rbsK"
                     /locus_tag="BKM31_RS04075"
                     /old_locus_tag="BKM31_04050"
     CDS             7502..8386
                     /EC_number="2.7.1.15"
                     /GO_function="GO:0004747 - ribokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019303 - D-ribose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rbsK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547222.1"
                     /locus_tag="BKM31_RS04075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04050"
                     /product="ribokinase"
                     /protein_id="WP_080036846.1"
                     /transl_table=11
                     /translation="MISVFGSANMDLVAYVAKAPKLGETVTGHRFRTVPGGKGANQAIA
                     AARAGGEVAFLGAVGDDGFGAEMRATLAEAGVDVRGLRQVPGSSGIAHIVVDDDGSNSI
                     IVVPGANGTVTGPSGEDLAVIAASSALLLQLELPMEAVVEAAQAGKVAGVQVFLTPAPA
                     QPLPAELLDAVSVLVPNEHEAAAITGVEGPEAALDALLELVEEAVITLGSDGALYGARS
                     GERLRVPSVKVDAVDTTAAGDTFVGALAVARTERRGMADALAFASMAAALSVQREGAST
                     SMPTRRQIEDALA"
     gene            8446..8655
                     /locus_tag="BKM31_RS04080"
                     /old_locus_tag="BKM31_04055"
     CDS             8446..8655
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS04080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_04055"
                     /product="hypothetical protein"
                     /protein_id="WP_080036847.1"
                     /transl_table=11
                     /translation="MSETSGELPEAVGGVSGESDVVAERSGCNTPKSRRPISADPPDEL
                     DEPEPEEAPGEDDDEIRPDVGPTG"
     gene            complement(9098..9793)
                     /locus_tag="BKM31_RS04085"
                     /old_locus_tag="BKM31_04060"
     CDS             complement(9098..9793)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631681.1"
                     /locus_tag="BKM31_RS04085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04060"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_080036848.1"
                     /transl_table=11
                     /translation="MPLGSLRPSPLVEQATEHLRAQITQGEWPVGTRLPGENALAKTLG
                     VGRSTVREALRALAGAGLVQARQGSGVFVIATEPAEEWPARLRRAAITDVYEVRVIVET
                     QAARLAAGRRTDEDVAALESALRERERAAAGDDTAFVDADIALHAAVVAAAGNPVLTDL
                     FAEFAPALRERLIDLVQLLELRAHDPNTGHDTHAALVAAIRRGDGDAAEGVLRAELEHT
                     LTLLHRQHP"
     misc_feature    complement(9829..9842)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.85"
                     /tool="antismash"
     gene            10001..11662
                     /locus_tag="BKM31_RS04090"
                     /old_locus_tag="BKM31_04065"
     CDS             10001..11662
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131420.1"
                     /locus_tag="BKM31_RS04090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04065"
                     /product="2-isopropylmalate synthase"
                     /protein_id="WP_080046483.1"
                     /sec_met_domain="HMGL-like (E-value: 3.8e-66, bitscore:
                     222.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPYHRYRPVHERVEVPLTGRAWPARRITEAPLWVPVDLRDGNQAL
                     AEPMDPERKRRMFELLVGMGFKEIEVGYPSSSRLDFDFIRHLATPGTVPEDVTVVVFTP
                     ARSELIERTFESIEGMSRVVVHLYTATAPTWREVVLGQDRAALHRMIRSSAEQIARLAG
                     DRDVRFQFSPEVFNLTEPDYVLEICNDLTALWDASPDRPVTHNLPATVEVATPNVYADQ
                     IEYMHRHLDRRDAVILSVHPHNDRGTGVACAELAVLAGAQRVEGCLFGNGERTGNVDLV
                     TLALNLHAQGVDPMIDLSDIDEVRRVVEHCNRLPVPERHPYAGDLVYTAFSGTHQDAIN
                     KGLAHHAKRAADLGVPPEQAPWEVPYLPIDPADVGRGYQAVIRVNSQSGKGGIAYLLNT
                     RYGLELPRRLQIDFSAVVQRATDGSGEEITAEQLWELFHATYLAPGEIGALEGWSTVET
                     GPGVHEFTGTLPGGRRLSGTGNGPLSALTAALAGDGIDVDILHYSEHALGPGKGGRAIA
                     YVEAKVNGTTCWGAAQDTSVLTASVHAVLAAVHRVI"
     gene            11678..12184
                     /locus_tag="BKM31_RS04095"
                     /old_locus_tag="BKM31_04070"
     CDS             11678..12184
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022167.4"
                     /locus_tag="BKM31_RS04095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04070"
                     /product="amino acid transporter"
                     /protein_id="WP_080036849.1"
                     /transl_table=11
                     /translation="MFEAGAVLGVLEALRKAGCAVWVAGGWGIDALVGRVTREHGDLDL
                     LHRAEQEPAVIAALESLGYAERTEGVVPGRPARFVMTGPGGRELDLHPLHFRPDGSALQ
                     RLDDEGGAFTYPAEVFVTGEIEGVRVPCLSVAQQVSFHQGYPPRERDLLDMARLRAAYG
                     IDTHF"
     gene            complement(12195..13010)
                     /gene="pyrF"
                     /locus_tag="BKM31_RS04100"
                     /old_locus_tag="BKM31_04075"
     CDS             complement(12195..13010)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547219.1"
                     /locus_tag="BKM31_RS04100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04075"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_080036850.1"
                     /transl_table=11
                     /translation="MNESFGSRLRARLDECGPLCVGIDPSPALLHTWGLDDSPAALERF
                     CRTVVEAVADVAAVVKPQSAFFERWGSRGIAVLERTIADLREAGTLVLLDVKRGDIDST
                     MAAYAEAYLDKGSPLAADAVTLSPYLGFGSLEGAITSAMANDAGVFVLARTSNPEAAGL
                     QRLVAGQVLAGAAAANAGHAPFGPVGVVMGATLPELEHSLDDLNGPILAPGLGAQGATP
                     ADVARLFGSVRHAVLPSVSRAVLSDPKLVRSRTLRYRDECAAHLAADAR"
     gene            13127..13603
                     /locus_tag="BKM31_RS04105"
                     /old_locus_tag="BKM31_04080"
     CDS             13127..13603
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS04105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_04080"
                     /product="DUF2283 domain-containing protein"
                     /protein_id="WP_080036851.1"
                     /transl_table=11
                     /translation="MYEIAHRVLTLRTDPPREVVVTVGVPFEEPTGEWSCPYRIDGLDG
                     WEHERKVSGLDSLEAVELAMVTVRAAVAGSHEAREGLLAWEEEPAGRRARTVYVSVDRA
                     RNLAYIAMKHEIVPGEAMRQFVAEDIVLDYGDAGQLLGLELTDAARLLPSELRL"
     gene            complement(13600..13956)
                     /locus_tag="BKM31_RS04110"
                     /old_locus_tag="BKM31_04085"
     CDS             complement(13600..13956)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890581.1"
                     /locus_tag="BKM31_RS04110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04085"
                     /product="hypothetical protein"
                     /protein_id="WP_080046484.1"
                     /transl_table=11
                     /translation="MTPRPDDRTASVFRFATELVAWVATPWALAPHSVALAVLSVIVLI
                     GLPTLFSTPGDKRNVIVAVPGFVTILLVLLQVVAAVAAAWVAWHAFAAALVSVLAVVTV
                     VLELPRWRWLLTRR"
     gene            14040..14843
                     /locus_tag="BKM31_RS04115"
                     /old_locus_tag="BKM31_04090"
     CDS             14040..14843
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179: hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547217.1"
                     /locus_tag="BKM31_RS04115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04090"
                     /product="HAD family hydrolase"
                     /protein_id="WP_222107486.1"
                     /transl_table=11
                     /translation="MSSFPRIVATDLDGTLLSDAGTVTPRTRQALQAARAAGAEIVFVT
                     ARAPRGVRGIARQAGVSGTAICSNGAVVYDLATDEITHQYPLDPRTARQVAQALALALP
                     GVGLAVETGRNILVEAAYTRRIEHDVAFYREVESVFDEDRPIVKLLALSPAHTADEMYA
                     AVAASIGDLAEVTYSGMEGLLEISAAGVTKAVTLGRLCAERGVEAGDVVAFGDMPNDLA
                     VLLYAGAGYAMANAHPMVLSAAGHRTLSNDEDGVAVVLENLLAAR"
     gene            complement(14894..15157)
                     /locus_tag="BKM31_RS04120"
                     /old_locus_tag="BKM31_04095"
     CDS             complement(14894..15157)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS04120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_04095"
                     /product="hypothetical protein"
                     /protein_id="WP_155126504.1"
                     /transl_table=11
                     /translation="MRVRGAAFAGLPAAVLALLCGTGAVAEAEDGGAKQGSSSLIGDVI
                     IFNDEIVEPVSLPVSTCGGLVPLLSKSPTTCEGASRVSDDDA"
     gene            complement(15201..15821)
                     /locus_tag="BKM31_RS04125"
                     /old_locus_tag="BKM31_04100"
     CDS             complement(15201..15821)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547215.1"
                     /locus_tag="BKM31_RS04125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04100"
                     /product="TIGR00645 family protein"
                     /protein_id="WP_080036853.1"
                     /transl_table=11
                     /translation="MRLARLSVADSPTESRTRSGRVGYIMFLSRWFQAPLYLGLIVAQV
                     VYVWRFMMELLHLVHLGFTGHPPETAVMLIVLGLVDVVMISNLLIMVIIGGYETFVSRL
                     RIEGHPDQPQWLSHVNANVLKVKLAMAIVGISSIHLLQIFINAARPTITDRELIWKTLI
                     HLTFVVSALALATIDRIMAGGRPQHGTGGAERPGQLQPERMAA"
     gene            complement(15821..15973)
                     /locus_tag="BKM31_RS59320"
     CDS             complement(15821..15973)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS59320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_155126507.1"
                     /transl_table=11
                     /translation="MKVRVVAALTALSALALAGGAPPITLDSLGSDPPRVDISTYVQHI
                     NLLTS"
     gene            complement(16093..16302)
                     /locus_tag="BKM31_RS04130"
                     /old_locus_tag="BKM31_04105"
     CDS             complement(16093..16302)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS04130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_04105"
                     /product="hypothetical protein"
                     /protein_id="WP_080036854.1"
                     /transl_table=11
                     /translation="MLFTVRRIAGAAVIAAGLTVLAAPASYAVVDPMVIAECLTHGATG
                     LPGAVDPAAPGLPAEMPGVSCLAP"
     misc_feature    complement(16353..16369)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.86"
                     /tool="antismash"
     misc_feature    16353..16369
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.85"
                     /tool="antismash"
     gene            complement(16404..16745)
                     /locus_tag="BKM31_RS04135"
                     /old_locus_tag="BKM31_04110"
     CDS             complement(16404..16745)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154231.1"
                     /locus_tag="BKM31_RS04135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04110"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_230465985.1"
                     /transl_table=11
                     /translation="MFLADCQARLAFDLMANTWNAVVVWALRHGPRRPGRLRAEIGGIS
                     TKVLTETLRRLEYNGLVARRVYAEAPPRVEYELTGLGRSLLGPIEAFGAWAADHGDEVM
                     AAQDRYEPA"
     misc_feature    16696..16711
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.22"
                     /tool="antismash"
     gene            16828..17475
                     /locus_tag="BKM31_RS04140"
                     /old_locus_tag="BKM31_04115"
     CDS             16828..17475
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893533.1"
                     /locus_tag="BKM31_RS04140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04115"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_080036855.1"
                     /transl_table=11
                     /translation="MRIGILGAGGMADALGTQWARAGHEVTVSGRDLSRSAAQAARMTA
                     AAGAEVRAASYAEAGAFGEVVVVAVREEGLLDTLQAAGAALRGKALIDVTNAAPLTYDL
                     TRSHARLIGDITGGHVVKAFNLCHVDVWRMTPPVFDGRPLAVPLCGDDPEALAATRTLV
                     ADLGCTPVDGGGLERAALLEATAAFMIGLWFGGTDAQAILPPLASSGAHGSS"
     gene            complement(17621..18280)
                     /locus_tag="BKM31_RS04145"
                     /old_locus_tag="BKM31_04120"
     CDS             complement(17621..18280)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547210.1"
                     /locus_tag="BKM31_RS04145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04120"
                     /product="endonuclease V"
                     /protein_id="WP_080046487.1"
                     /transl_table=11
                     /translation="MHVKQLHPWPGSVAEAEAVQDRLRGEVELSGPDSFALVAGLDVHY
                     RGDDALTAAVVVLDGGTLEPVEEVVAHGEAAFPYVPGLFAFRELPALVAALERLTVTPD
                     LLVCDGYGLAHPRGFGLACHLGVLTGLPALGVGKTPFVGTHEPPGPERGAWTPIVHEGA
                     TVGRALRTQREVKPVYVSQGHRISLDVATDQVLRLTPRYRLPEPVRRADHLARHPS"
     gene            18299..19843
                     /locus_tag="BKM31_RS61985"
                     /old_locus_tag="BKM31_04125"
     CDS             18299..19843
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019474.4"
                     /locus_tag="BKM31_RS61985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04125"
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="WP_222107485.1"
                     /transl_table=11
                     /translation="MREVLVIVGPEVVADAELLGEIARREFAALGVAGRLVHARDAAHV
                     RSLMRTEDVVVVVPAPGPDARTLLRQPPGSGVVVPVDIDRVPGARHIHGRGLAGLAWAI
                     RHAVHRARHPQVRRIPYGPSPEQWGDLYLPPAPQAGAAVPDADPAETPRATEGRAETPG
                     AAGERAEVPGTGRHAEVPSAAGGRAEVPGAAGVPGRVPVVALVHGGYWRSEWAADLMEA
                     LCADLAARGFAVWNLEYRRPDLHGWAATRQDVTAGLAALHAIGPATPTGPTLAARRAQP
                     GNGPDASDRAEPRNGPDAADPAELRNGPGAADRAELRNGPDAPDRAEPRNGPDTPDRAE
                     PQPPSVAPGLAVPEAPSLDLDRIVVAGHSAGAQLALRAVADGARVALAVSLAGVLDLEQ
                     TDRRWLSHGAMAAALTGGEAPAPALDHGSLDEGELLASSPLLRLPLGVPQIVVQGRGDD
                     VNLVDFSRRYVAAARQAGDEVAYLELPGDHQDVITPGTPIWQATAAAITRVVTAVT"
     gene            19792..21189
                     /locus_tag="BKM31_RS04155"
                     /old_locus_tag="BKM31_04130"
     CDS             19792..21189
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="BKM31_RS04155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04130"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_329607761.1"
                     /sec_met_domain="DAO (E-value: 6.5e-08, bitscore: 32.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGDGRRHHQSRHRRHLDNPRPPPYEGEMEVSIVGAGLVGCLLAC
                     YLARRGHRVTLYERRPDPRERGPDRGRSINLAISRRGIDALSRIGLDGKVLHAALPMAG
                     RMMHGMDGALTFQPYSADRSQAINSIGRADLNRELLEAASAQPGVEVRFGCRLTGLDER
                     TGRLRFASGEEAEAGVVIGADGAYSAVRARLQQLPGVSFSQEYLDYGYKELSIPPQDGR
                     FALDPGALHIWPRGRSMMIALPNQDRSFTCTLFWPHDTLAALDTPQRIRAYFAEHYRDA
                     FGLMPDLVPDFRGNPVGHLVTMRCSPWHAGGGDAVVGLVGDAAHAIVPFYGQGANCGFE
                     DCVELDRCLDEAGDDFPRALELFERRKADTDVIARLALDNFVEMRDKVGSRVFLAGKRL
                     EHALERVLPGYVSRYELISFSTTPYSQVERRVARQRRLAVAAGAALVALGFAARRGRGL
                     VRTPEAD"
     misc_feature    20290..20292
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21200..22813
                     /locus_tag="BKM31_RS04160"
                     /old_locus_tag="BKM31_04135"
     CDS             21200..22813
                     /NRPS_PKS="Domain: AMP-binding (22-427). E-value: 3.1e-112.
                     Score: 367.1. Matches aSDomain:
                     nrpspksdomains_BKM31_RS04160_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132328.1"
                     /locus_tag="BKM31_RS04160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04135"
                     /product="AMP-binding protein"
                     /protein_id="WP_080036857.1"
                     /sec_met_domain="AMP-binding (E-value: 4.8e-115, bitscore:
                     383.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSYSSATADTPLLGETIGENLERTVARFGDREALVDVPSGRRWT
                     YTQLDADVDDLARALLARGIAKGDRVGIWAPNRAEWVIVQYATAKVGAILVNVNPAYRT
                     HELRYVVEQSGMRLLISALSHKGSDYRAMVTEVGFSDVVYLDDPSWERLTEVKADPAAL
                     RARMAELAFDDPINIQYTSGTTGFPKGATLSHHNILNNGFFVGELIHYTEADRVCLPVP
                     FYHCFGMVMGNLGATSHGSCIVIPSPGFDAEATLRAVEEERCTSLYGVPTMFIAELALA
                     AKFDLSSLRTGIMAGSPCPVEVMKRVVGEMNMGEVAICYGMTETSPVSTMTRSDDDLAR
                     RTETVGRVMPHVEVKIVDPETRLTVPRGEPGELCTRGYSVMLGYWNQPDKTAEAIDAAR
                     WMHTGDLATMDEHGYVNVVGRIKDLIIRGGENIYPREIEEFLYGHPDIADVQVIGVPDE
                     RYGEEVMAWVIMRPGTEPLTPERLREYCAGRLAHFKIPRYVHVVDAFPLTVTGKIRKVE
                     MRERSVELLGLRDAAGIRNA"
     aSDomain        21266..22480
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS04160_AMP-binding.1"
                     /evalue="3.10E-112"
                     /label="BKM31_RS04160_AMP-binding.1"
                     /locus_tag="BKM31_RS04160"
                     /protein_end="427"
                     /protein_start="22"
                     /score="367.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ERTVARFGDREALVDVPSGRRWTYTQLDADVDDLARALLARGIAK
                     GDRVGIWAPNRAEWVIVQYATAKVGAILVNVNPAYRTHELRYVVEQSGMRLLISALSHK
                     GSDYRAMVTEVGFSDVVYLDDPSWERLTEVKADPAALRARMAELAFDDPINIQYTSGTT
                     GFPKGATLSHHNILNNGFFVGELIHYTEADRVCLPVPFYHCFGMVMGNLGATSHGSCIV
                     IPSPGFDAEATLRAVEEERCTSLYGVPTMFIAELALAAKFDLSSLRTGIMAGSPCPVEV
                     MKRVVGEMNMGEVAICYGMTETSPVSTMTRSDDDLARRTETVGRVMPHVEVKIVDPETR
                     LTVPRGEPGELCTRGYSVMLGYWNQPDKTAEAIDAARWMHTGDLATMDEHGYVNVVGRI
                     KDLIIR"
     CDS_motif       21731..21784
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS04160_0001"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="BKM31_RS04160"
                     /protein_end="195"
                     /protein_start="177"
                     /score="17.9"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGATLSH"
     CDS_motif       22295..22381
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS04160_0002"
                     /evalue="8.10E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="BKM31_RS04160"
                     /protein_end="394"
                     /protein_start="365"
                     /score="34.2"
                     /tool="antismash"
                     /translation="PRGEPGELCTRGYSVMLGYWNQPDKTAEA"
     CDS_motif       22451..22513
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS04160_0003"
                     /evalue="3.70E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="BKM31_RS04160"
                     /protein_end="438"
                     /protein_start="417"
                     /score="10.2"
                     /tool="antismash"
                     /translation="VGRIKDLIIRGGENIYPREIE"
     gene            complement(22863..23612)
                     /locus_tag="BKM31_RS04165"
                     /old_locus_tag="BKM31_04140"
     CDS             complement(22863..23612)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249: carbamoyl phosphate synthase small subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547208.1"
                     /locus_tag="BKM31_RS04165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04140"
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="WP_080036858.1"
                     /transl_table=11
                     /translation="MADVLVIQNSTSGGPSRMAGWLEEGGLTLDVVPAHAGAPLPGGLR
                     HDAMIMLGGGYLPGDDERAPWLRDARRLMEQALAAGVPVFGICLGGQMLAQVAGGEVRA
                     NSGTPENGSLPVTIRPEAATDPLFHGLPPVVPAIEHHKDAVTRLPGGAAHLAETGACPY
                     QAFRVGERAWGVQFHPEVLPARIREWRVEGFDPDEVYARAVADEPVSTPVWRTVIGRFA
                     ALATAGTAAGTTAGTVAGTATGVSGAA"
     gene            complement(23605..24462)
                     /locus_tag="BKM31_RS04170"
                     /old_locus_tag="BKM31_04145"
     CDS             complement(23605..24462)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017585105.1"
                     /locus_tag="BKM31_RS04170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04145"
                     /product="bifunctional 5,10-methylenetetrahydrofolate
                     dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_080036859.1"
                     /transl_table=11
                     /translation="MKTLTGKDLAAAIRARTQAEAAAGPQPRLAVVVATADEASLWYVR
                     SIAKAAAGVGIACDVVDLGPEAAPGRIRETLARLSADPQVHGLMLQTPLPPGASAQELA
                     AAIDPGKDVDGANPLSLGRLAAGLPAFPPATAAAVLALLDHYEVELAGRRAVVVGRSTV
                     VGKPLAHLLLDRHATVTVCHSRTRDLAAVTSQAEVLVAAAGRAGLIGAAHVAMGAVVID
                     VGTNPTDDGGLTGDVDFAAVSNVAGALTPVPGGVGPVTTALLLSHTARAANRPHDPQEE
                     AHDG"
     gene            complement(24459..25061)
                     /locus_tag="BKM31_RS04175"
                     /old_locus_tag="BKM31_04150"
     CDS             complement(24459..25061)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012887125.1"
                     /locus_tag="BKM31_RS04175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04150"
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="WP_080036860.1"
                     /transl_table=11
                     /translation="MRDLKIVDFLDQLADRVPAPGGGATAALHAAQAAALLGMVARYTT
                     GEKYTEHAETVVAVIAETDSLRARALRLAEEDAAAFTAVTDAYRLPKGEERSAAIARAL
                     AGAAEPPARVAETATRLVELCELLLPIGNRNVVTDVAAAADAARAALTTARVNVEINLR
                     GIKDERVREELNIRISGVDAAVARADWVTAEVREEIS"
     gene            complement(25090..25599)
                     /locus_tag="BKM31_RS04180"
                     /old_locus_tag="BKM31_04155"
     CDS             complement(25090..25599)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS04180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_04155"
                     /product="hypothetical protein"
                     /protein_id="WP_080036861.1"
                     /transl_table=11
                     /translation="MVAGLLLPPLVAAGLWYGVGDLTLQAQQAFRISWVAVGVLAATAV
                     VLAFLAGSRLSPVASLLGGLAFAAAGVLPFAEMFTRVRLLPLDLLPGVLRSGFTTTAHS
                     GLLAVVGVTLLVVSLFPSRWRGSVRDLAEQPVAYESAWGTASPSQSPYLPPYNSPEDTT
                     RPMYRE"
     gene            complement(25679..26665)
                     /locus_tag="BKM31_RS04185"
                     /old_locus_tag="BKM31_04160"
     CDS             complement(25679..26665)
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013592.4"
                     /locus_tag="BKM31_RS04185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04160"
                     /product="M1 family aminopeptidase"
                     /protein_id="WP_155126510.1"
                     /transl_table=11
                     /translation="MAEPPVDAKQRREDISMLGFRIGGGGRAWALQEPFGAFTWFPVND
                     HPSDEALYDVAITVPKGWSGVAHGTYKGKTTEGRSSTFRWQSTDPVASYLTLFAADKFR
                     MFTDKGPRGIPITYWIRPQDVRKQLPVARRMPAILRWLEKKLGPYPFPSAGLVATSDSG
                     METQQMVALGPRYMEPSVVAHELAHHWFGDTVTPRTWRDMWMNEGFAMYFEMQWYADHE
                     DGTIDAFISNIRAYDAELRRENGPPGKYRRDAFGQSNVYYSPAIMLHEIRKRLGDKKFW
                     AMTRAWPQEHRNTTQDRAAFVKWINEHTGRNFTKHINTWLDSKTTPR"
     gene            26747..28276
                     /locus_tag="BKM31_RS04190"
                     /old_locus_tag="BKM31_04165"
     CDS             26747..28276
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1206: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033550.5"
                     /locus_tag="BKM31_RS04190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04165"
                     /product="ISL3 family transposase"
                     /protein_id="WP_155126513.1"
                     /transl_table=11
                     /translation="MVNVLFPHLAAVEIEQVDRQDGQIRVVARTRGDPVCCPSCGTATG
                     KVHGYHRRRLADRPVDGLPVVIELRLRRLVCINLDCARQTFHEQVPGLAGRYGRRTAGA
                     TALVIACALALAGRAGASLLATIGLLLSRTSVLSTLMALPEPPSTVPAVIGVDDFAIKR
                     GQRYATIIIDAVTHRCLDVLPDRLGVTFAHWLQAHPGVQLICRDRSAAYAAGARDGAPQ
                     AVQCADRWHLLNNLSEAVEKLALAHRGCFRDIATGQGRDEGPTVRRTRSRYAAIHALLG
                     QGVTNNEIARRLHLALNTVKKYARAPHVEQLIGGSKRGATLVDPFRDYLRSRRAAEPGV
                     TVWALLREIKSMGYQGGSTLLYRYLGQGRAEDAPAPPSPRRVASWIMTDPAHLSPGRTT
                     RLQEVLDCCLELKQATEHVRTFADLLTQRQGHRLDDWIADVRAGDLHPLRSFAEGLLID
                     HDAVVAGLTLPYSNGPTEGVINKIKLLKRQMYGRAGLALLRKRILLTIASN"
     misc_feature    26957..26959
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(28878..28892)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.03"
                     /tool="antismash"
     gene            28952..29863
                     /locus_tag="BKM31_RS04200"
                     /old_locus_tag="BKM31_04175"
     CDS             28952..29863
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547206.1"
                     /locus_tag="BKM31_RS04200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04175"
                     /product="superoxide dismutase"
                     /protein_id="WP_080046490.1"
                     /transl_table=11
                     /translation="MRSAILKTALGSAMLVVLLGGVPAQAATKPDTFPLPNGFQPEGIA
                     IGGRYAYFGSRATGDIYRADLRTGQGGVISKGPGTPSLGLKTDGRGRLFVAGGNAGNAR
                     VIDLRTGAVLKSYQLATGTSFVNDVILAGRAAYYTDSANPVLYKLELGRGGALPAEAVK
                     IPLSGAIQYTTGNNANGIAPSPDGRSLLIVQSNTGKLFEVDPSSGVTTEVDLGGESLVN
                     GDGLLLAGRTLYVVQNRLNTVAAIALTRDGASGKLIRRLTDDRFDVPTTVAAHGRRLYL
                     PNARFTTTPTPDTTYDVVSVKP"
     gene            complement(29875..30630)
                     /locus_tag="BKM31_RS04205"
                     /old_locus_tag="BKM31_04180"
     CDS             complement(29875..30630)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888783.1"
                     /locus_tag="BKM31_RS04205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04180"
                     /product="chitosanase"
                     /protein_id="WP_281261968.1"
                     /transl_table=11
                     /translation="MLTATLLALSLTVSSPALTDPHKKDIAMRLVSSAENSSLDWKAQY
                     GYIEDIKDERGYTAGIIGFCSGTGDMLELVELYTERKPDNVLAKYLPALRKVNGTDSHK
                     GLEPNFPKDWKTAAKDPVFQQAQNDERDRVYFNPAVTQAQKDGLRALGQFVYYDAMVMH
                     GPGNDKLSFGGIRKAALGKAKPPAQGGNEVTYLNAFLDARKTAMKAEDAHEDTTRVDTM
                     QRVFLKNGNLDLNPPLTWKVYGDSYTIKK"
     gene            complement(30702..31307)
                     /locus_tag="BKM31_RS04210"
                     /old_locus_tag="BKM31_04185"
     CDS             complement(30702..31307)
                     /EC_number="1.5.1.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547205.1"
                     /locus_tag="BKM31_RS04210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04185"
                     /product="FMN reductase"
                     /protein_id="WP_080036864.1"
                     /transl_table=11
                     /translation="MKLVVVTAGLTQPSSTRLLADRLAEAVAQRAEVEVRVVELRDLAV
                     DIANAFVTGFPNTRLREVAEAVTAADGLIAVTPIFSGSYSGLFKSFFDVLDNTALTGKP
                     VLIAATGGTARHSLALEHALRPLFAYLRAVVVPTAVYAAAEDWGGGRDAFTDGLGERIG
                     RAAQELADLLLHRAPRAEETVEEVVPFEQQLAALRRTE"
     gene            complement(31341..32462)
                     /locus_tag="BKM31_RS04215"
                     /old_locus_tag="BKM31_04190"
     CDS             complement(31341..32462)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547204.1"
                     /locus_tag="BKM31_RS04215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_04190"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_080036865.1"
                     /transl_table=11
                     /translation="MQFGIFSVGDVTTDPTTGRTPTEHERIKAMVAIALKAEEVGLDVF
                     ATGEHHNPPFVPSSPTTMLGYIAARTERLQLSTATTLITTNDPVKIAEDFAMLQHLADG
                     RVDLMLGRGNTGPVYPWFGQDIRQGIPLAIENYALLHKLWREDVVDWEGRFRTPLQGFT
                     STPRPLDGVPPFVWHGSIRSPEIAEQAAYYGDGFFANNIFWPKEHFMRLISLYRQRYAH
                     YGHGTPEQAVVGLGGQVFMRKNSQDAVREFRPYFDVAPVYGHGPSLEEFMAETPLTVGS
                     PQQVIDRTLEFREFFGDYQRQLFLMDHAGLPLKTVLEQLDLLGEEVVPVLRKEFAKDRP
                     ADVPDAPTHASLLAAKNAAKNAVEDAPEAPVGA"
ORIGIN
        1 ggcctggcgt tcaccgacgc ccgcaacacc cgcgtccacc agacggagtt cgtgggcctg
       61 gagaacttca cccggctgct gaccgacgcg gagttctggt cgtcgttcca gatcggtgcc
      121 atctgggcgg tctccgtgac cgtgctgcag ttcctggccg cgctgggcct ggcgctgctg
      181 ctgaacgaga agctgcgctt cagcggcctg gcgcgggtgc tgtcggtggt gccgtgggcg
      241 atgccgccgg tggtcatcgg cctgatgtgg aagctcgtct accaccccga cgcgggcatg
      301 ctgaacgacc tgctcggcac gcacatcaac tggctggccg acttctcgct cgcgctgccc
      361 gcgatcatcg tggtcggcat ctgggccggc atgccgcaga cgacggtcgt gctgctggcc
      421 ggcctgcaga acgtcccgaa ggagctgtac gaggccggcg agatggacgg cgcgggcacc
      481 tggcggcgct tctggagcat cacgctgccg cagctgcgcc cggtgatcgt ggcgatcacc
      541 tcgctcgact tcgtgtggaa catcaaccag ttcggcctgg tctacgtgct cacgcaaggc
      601 gggccgggcg gtcgtacgcg gctgccgatg ttgttcgcct acgaggaggc gttcaggtac
      661 cgcatggccg gttacgcctc gatgctcggc ctcgccatgg cgatcgtcgt gctcgcggtg
      721 ctcggcctgt acctgtggcg ccagatgagg gaggccaagt gagacgcgtt ctccagtacg
      781 tcgcgctggt cgcgtacgtc gtcttcctgg cgttcccgct gctgtggctg ctgtccacgg
      841 cgctgaagac gccgcaggag atggcgctga cggagccgac gtggatcccg cgcgagccga
      901 cgctggccaa cttcggcgac gcgttcggcg agcaggacct cgtcggagcg gcgctgcgca
      961 gcctggtggt ggcgttgttc gcgagcgtga tcacggtgct gatctcgctg cccgccgcct
     1021 acgccatggc gcgttaccgc ggcctgctca acaaggtcgc gatcgggtgg gtgctggtca
     1081 gccaggtgtt cccgttcatc ctgatcatca tcccgctctt catgatcctg cgcgacctcg
     1141 acctggtgaa cacgctgccg gggctggtgg tcgtgcacgt gacgttcacg ctgccgttcg
     1201 cgctgtggat gttgcagggg tacgtgcgcg cggtgccgcg cgagctggag gaggccgcgg
     1261 ccgtggacgg cgcgggccgg ctgcgctcga tcgccagcgt ggtcgccccg ctgctcgcgc
     1321 cgggcgtcgt cgccaccctg ctgttctcgt tcatctcgtc atggaacgag ttcatgttcg
     1381 cgctcgtcgt cctgcagaac cccgacgtca tgacgctccc gctcacgctg gtgaggttca
     1441 ccggccccga gggggtggcc aggctcggcc cgctggccgc ggcgtcgctc atggcgacga
     1501 tcccgagcct gatcttcttc gcaatcattc agcggcgact gaagtccggc ctgatggccg
     1561 gcgccgtcaa gggctaggag gctcatatgc gaatcacgtc cgctctggcg gctgcggcga
     1621 tcctcacgct cgccgccgcg tgcggcgggg gaggaggcgg cggctcgtcg tccgccccca
     1681 acgagcccgt caagatcaat ttcctcagcc tggcgtggca gaaggagtcc gtcgccgcga
     1741 acaagcagct cgtggacgag tggaacaagg ccaacccgaa catccaggtc acctacgtcc
     1801 agggcagctg ggacaacgtc aacgaccagc tcgtcaccca gttcgccggc ggcaccgcgc
     1861 ccgacgtcat ccacaacgac tcgcccgccc tgtccggctt cgcctccgac ggctacctgc
     1921 tcgacctgaa ggacaaactg cccgccgagc tcaagagcga catcccgcag tccgcctggg
     1981 acaccgtcac cttcgacgac ggcaagggcg gccagggcgt gtacggcgtg ccgttcctcc
     2041 aggagtcgca ggtcatcatc gccaacaaga agctcctcga cgccgccaag gtgcgcatcc
     2101 ccaccgcgga cgacccgtgg acctgggacg agttctccga ggccgccaag aagatgacca
     2161 aggacggctc gtacggcgtc gcctgggcca tgaagtcgcc cgtcaacaag accctcaacc
     2221 tggcgctcaa cttcggcggc accttcttcc agacctccgg cggcaagacc accgtcaagg
     2281 tcggccccga ggagcgcgag gtgctccagc gcatccacga ccagctctac aaggacaagt
     2341 ccgccgaccc cgacgcgctc ggccagggca ccgccgaccc gctgcccgcc ttctacaagg
     2401 gcaagttcgc gatgctgccc gccggcgtct acctgcgcca gcaggtcgtc gagcaggcgc
     2461 ccgacgggtt cgagtgggtc acgctgcccg cgcccaaggg caccagcgcg cagcagggcg
     2521 ccgtctccca gacgctgtcg atcgcgcagg agagcgagca cccggacgag gccatgaagt
     2581 tcatctcgtt cttcctcaac ggcaccaacc aggccaagct cgccaagggc gactggctcc
     2641 tgcccacctc ccagaaggcc gccgccgacc cggccatgac caccgaggag aacggctggg
     2701 acgtcgccac cgcctccgcc aagaacctcg tcgtcgcgcc gttcctcaag gtgaacgggt
     2761 tcgacgaatg gaagagcaag gtcgccacgc cggcgctgca ggagtacttc gccaataaga
     2821 tcaccatcga ccaggcggcg gcgaagctgg tcgaggacgg gaacaaggtg ttggagcggt
     2881 accagcggtg atcacagcgc gggaacgggc ccgagggtgc ctgctcggcc tcgcggccgg
     2941 cgacgccctc ggcgccccgg ccgagaacct cacgccgcag gagatccggc ggcggtgggg
     3001 ccggctcacc gagatcgagg gcggcggcac cgacgacacc gagtacgcca tcttcgccgc
     3061 ctccctcctc gtccgccacg gacacgccct caccccggcc gacgtcgccg ccgcctaccg
     3121 cacggagatc atcccgctgg tgacggggcc gatgcgcggg gccggcttct ccgagctcgg
     3181 caccgtcgag gcgctccgcc gcggcctcca gcccccgctg acggggctgg tccactcgca
     3241 cggctggtcc gacggcctcg ccatgcgcgc cgccccctac ggcatcttct gcccggggga
     3301 cccggcggag gcggcccggc tggtggagca ggacggcctg gtcagcggct ccggcgaggg
     3361 catcctgggc ggccgcgcca tcgccgccgc cgtcgcctcg gccatggccg gcgcctcgcc
     3421 ccacgaggtg gtgcgcgcgg ccctgtcggt cgtcccggcc gactcgtgga cggccaggaa
     3481 cgtggtgcgc gcctgcgaaa ccctcggctg gtccccaccc accgccacca cgggcatcgc
     3541 cgctgcgacg accaccccga gcaccgagct cgcaccggcg cgcccgggtg ccggcgccga
     3601 ggcaccgccg cccagcggtc ttcccagcgc cggtgcggcg ggtagtaggt cggtggagtc
     3661 cggcgcaacg cgtgcggcgg ccgggcatgc caccggcgat ggggccgagg tggtcgaggc
     3721 gttgcatcgg gccgtcgtgg tcgagcacta cccctggacg gacatcgccc ccgaggcggt
     3781 cgcgctggcc ctggccgcgt tcctggccgg ggacggtgac gtcgagcggg cggtgacgtt
     3841 cggggtgagc ctggggcggg acgccgacac gatcggcgcg atcgcgggcg ccatcgccgg
     3901 ggcgagccag ggcgagcggg gcgttcccgc gcgctgggcc gccaggatcg ggcccgtgac
     3961 gggcaagtgc ctgcccgtcg tggcaggaag acacgtgctg gacgtcgccg acgagctggc
     4021 gggaggactg tagaacacca tgtcggggga cagaatcagg ggggccgtca tcggtctcgc
     4081 cgtcggtgac gccgtgggct ggccggcggg caggcaccgc gccgccctgc acgcgccctg
     4141 gagccgccgc ctgcaccgcg agctggacgc gttcgccgag gagcaccgtg tcacgacgct
     4201 cccggtgccg ttcgcgctga accagccgac cgcgccgctg cgggtgggcc cgtcggacga
     4261 cgccgagtgg ctggcgtgga cgctgctgac cgccgaccgc ccgcgcgccg aggcgttcag
     4321 agagcttgtc ggtacggacg gcggcgcgca agccgatgcg cggcccatca ggggacggat
     4381 ctccgtgatg accgcgctgg acaacctggc caagggcgtc gagccgcccg cctccggcca
     4441 cgacaacccg caccatttcg acgacgccgc cgccgtcagg gccgtcgcgt acgggatcct
     4501 ggggagggac ccgacgccgg acgcccaggt gacgaacgcg ggcgacggcg tgccggccgc
     4561 ccgggcgatg gccgccgcca tccaggaggc cgtggcgtcg gggagcgcgg gggcggcggt
     4621 cgaggcggcg ctggccgtcc tgccgccgga caccgccatc ggccacaacg cccgcctggc
     4681 gctggatgtc gccaggaagg cgggcgaccc gttcggcgcg atccccgcgc tggacgcggc
     4741 gctgctcgac cacgtctaca gctacggcgt gggcgccgcg cagaccgtcc cggtggcgct
     4801 ggcgctggtg gagacggcgg gcggggagct cgccagggcg gtgccggcgg cggcctgcct
     4861 ggctccgctg gccgactcgg cgcccgcgct cgccggagcg ctggcggggg cgtgcggcgg
     4921 gtacgaggcg atcccggagg ggtggaccgc ctcggcccgc acgctggccg gctgctgcct
     4981 gcctgacctg gcgggccgtg atctgatcga actactggag ggaatcgcat gacgccgctt
     5041 gaggacaggg ccactggctg cgtggcgggg gcggcggtcg gtgacgcgct gggcggcgcc
     5101 accgagggct ggactcccga gcagatcgtg cagcggtacg ggggccgcgt cgagggcatc
     5161 gtgccgccgt tcaacgagga ctggcgcaac gcgcgcccta tcgccccgta ccacaagggc
     5221 gacggccaca tcacggacga cacgttgatg acgcacgccc tgatccgcgt gtacgcgaag
     5281 gtgggcggcc acctggacgc gtacgcgatg gccgagcacc tggtcccgga gctgatgggg
     5341 gagcggcgct ggatcccgga gctggaggcg gaggcgctgc cgttgcagcg catcttcctg
     5401 gcggagaagt ggatcgtggc gcgcctgcac tacgggcacg cggacccgcg cgaggcgggc
     5461 gtgggcaaca tcgtgaactg cggcgccgcc atgtacgtgg cgccggtcgg catcgtgaac
     5521 gccgccgacc ccgacgccgc gtacgccgag gcgatcgagc tgacgggcgc gcaccagtcg
     5581 agctacggcc gggaggcggc gggcgtcatg gccgccgcgg tggcggaggc gatgcggccg
     5641 ggtgcgacgg ccgactcggt ggtgggggcg tgcctgcgcc tggccaagga cggcacgcgg
     5701 gccgccatcg aggcggtctg cgaggcggcg gccgggctgg ggcactggga cggctcgttc
     5761 gaggcgctgc gggcagccgt gcggccgttc gacacggtcg ccgacaccta ccgtgaccag
     5821 gggctggggg cgcgccggcc gagccgggtg cacagcatcg aggagctgcc gctggcgctc
     5881 gggttcctgg tgatcgcgaa gggcgacttc cgcgacaccg tgctgggcgg cgtgaactac
     5941 gggcgcgacg ccgactcgat cgcgtccatg ggcggcgcca tcgccggtgc gctgggcggc
     6001 ctggagtcgg tgccgcagga gtgggtgacg caggtggcgg cggccagccg cacggatttg
     6061 gtggcgccgg ggctggccat cgcggcggtg gcgcgccgcg tgcacgccga cgatctggta
     6121 cgccgccgcg cccacgagtc cgccttcgcc gagctcgagc gcgcatgatc aggctcacct
     6181 gggtccagcc ggaggacctc gtcggccacg agctgcgcca ggccacggag gacggcaggg
     6241 acggccggga tgttcgaagc atcgcggccc gctggcacgc ggcgggcggt cacgacgccc
     6301 cgccccgcgc gggcgcctcg gagccgggcg cggcccggct gcgcggcctg gcggaggagc
     6361 tgctggacga gctggccgcc gtcccgtccc cgctgccgga gccgtcggac ctgcccggca
     6421 tcatcgcggc ctgccccgcg tggcccgata agagcgctgg ggcaggcgcg gtggatccgg
     6481 aacgggtgct cggggcgtgg ctggggcggg cggccgggtg cgtgctgggc aagccggtcg
     6541 agaagatccc gcgcgcgggc atcagggaga tcgcgcaggc caccggcaac tggccgatcc
     6601 gcggctggtt cacggccaag ggcctgccgg acgacgtggc ccgccgctgg ccgtggaacc
     6661 gccgtagcgc cgtcaactcc ctggccgaga acatcgacgg catccccgag gacgacgacc
     6721 tcaactaccc gctgctcgcc ctgtccctcc tggagcggca cggccgcggc ttcaccaccg
     6781 aggacgtggc ccggctgtgg ctggacgagc tcccggcggg ccgcacgttc accgcggagc
     6841 gcatcgcgta ccgcaacctg ctggacggtg tggagccgcc ggcgacggcc acctaccgca
     6901 acccgttcag ggagtggatc ggcgcgctga tcagggcgga cgtgtacggc tgggtgaacc
     6961 cgggcgaccc ggcgaccgcg gccgagtacg cctggcgcga cgcccggctc acgcacaccg
     7021 cgaacgggat ctacggggcg atgttcgcgg cggcgatgtg cgcggcctcc atggtggcga
     7081 cgtcggcgga ggaggtcgtg cgggcgggcc tgtcggtggt gccggagggg tcgcggctgc
     7141 acgaggccgt acgcctggcc gccgaggacg cggccggcga ggacgacttc gagcgggtcg
     7201 tggaccgcct gcacgagcgg cacggccacc tgcactgggt gcacacgatc aacaacgccg
     7261 ccctcgtggc ggccacgctg atccacggca agggtgactt caccgccacg atcgccggcg
     7321 cggtggccgg cggctgggac accgactcgg ccggcgccac ggcgggggcc gtcgcgggcg
     7381 cgctggccgg aggcgtgccg gagcgatggc gcatgcgtga cagcctggcc agcagcctga
     7441 cgggtttcga cggggtgggt cttgccgagc tggccgcccg tacgcaggag atgatgaagc
     7501 catgatctcg gttttcggca gcgccaacat ggacctcgtc gcgtacgtcg cgaaagcccc
     7561 caagctgggc gagacggtca ccggtcaccg gttccgcacc gtgcccggcg ggaagggcgc
     7621 caaccaggcg atcgccgccg cgcgcgccgg cggcgaggtg gcgttcctgg gggcggtggg
     7681 cgacgacggg ttcggggcgg agatgcgcgc cacgctcgcg gaggccgggg tggacgtgcg
     7741 cggcctgcgc caggtgcccg gctccagcgg catcgcgcac atcgtggtcg acgacgacgg
     7801 ctcgaactcg atcatcgtcg tccccggcgc gaacggcacc gtcaccggcc cctccggcga
     7861 ggacctggcc gtgatcgccg cgtccagcgc gctgctgctc cagctcgaac tgcccatgga
     7921 ggcggtcgtg gaggccgcgc aggccggcaa ggtggccggc gtgcaggtct tcctcacgcc
     7981 cgcgcccgcc cagccgctgc ccgccgagct gctcgacgcc gtctcggttc tcgtgccgaa
     8041 cgagcacgag gccgccgcca tcaccggcgt cgaagggccc gaggccgccc tggacgcgct
     8101 gctggagctg gtcgaggagg ccgtgatcac gctgggctcc gacggcgccc tgtacggggc
     8161 gcggtcgggg gagcggctgc gggtgccgtc ggtgaaggtg gacgcggtcg acacgacggc
     8221 ggccggcgac acgttcgtgg gggcgctggc ggtggcgcgc accgagcggc gcggcatggc
     8281 cgacgcgctc gccttcgcct ccatggcggc ggcgctgtcg gtgcagcgcg agggcgccag
     8341 cacctcgatg ccgacccgcc gccagatcga ggacgccctc gcctgacctg ccccttcacc
     8401 gggttctggc gggttcgggc gggtccgtcg gggcaggtga gggccatgag tgagacatcc
     8461 ggcgagctgc cggaagccgt gggcggggtg agcggggaga gcgacgtggt cgccgagcgc
     8521 tcgggctgca acaccccgaa gtcgcgccgc ccgatctcgg ccgacccgcc cgacgagctg
     8581 gacgagcccg agccggagga ggcgccgggc gaggacgacg acgagatccg cccggacgta
     8641 ggccccaccg gctgaccccg gccgcccaaa ggcgcccacg cgtccacgcg tgtcacgcag
     8701 gccacgccag ccaccgccgc cacgcgtgcc cgccatgccc cacgcgcgct cgccacggcc
     8761 acaggcggcc acgcctgcca cggggccacg cccgcccact acgcgcgccg gcaccacgcg
     8821 cgccggcacc acgcgcgccg gcaccacgcg cgccggcacc acgcgcgccg gcaccacgcg
     8881 cgccggcacc acgcgcgccg gcaccagtgc gcccaccacg ggtgcccacc acgggcggcc
     8941 gccacggcca caggcggcca cgcctgccac gccagccacc ggcgccacgc ccgcccacta
     9001 cgcgcgtccg ccacgcgcgc ccaccacgca tgcccgacca cgcgcgcccg ccgcagggga
     9061 gcggagccgg gcggtcacgg ggctgtcggt gggctggtca ggggtgctga cggtggagga
     9121 gggtgagggt gtgctccagc tccgcccgca ggaccccctc ggccgcgtcg ccgtcgcctc
     9181 gccggatggc cgccaccagc gccgcgtgcg tgtcgtgccc ggtgttggga tcgtgtgccc
     9241 gcagctccag cagctgcaca aggtcgatca gccgctcccg cagcgcgggg gcgaactcgg
     9301 cgaacaggtc ggtcagcacc gggttgcccg ccgccgcgac gacggccgcg tgcagcgcga
     9361 tgtcggcgtc cacgaaggcc gtgtcgtcgc cggccgccgc ccgctcgcgc tcgcgcagcg
     9421 ccgactccag cgccgccacg tcctcgtcgg tacgccgccc ggccgccagc cgcgccgcct
     9481 gggtctcgac gatgacgcgc acctcgtaca cgtcggtgat ggcggcgcgc cggagccggg
     9541 cgggccactc ctcggcgggc tcggtggcga tcacgaacac gccggaccct tggcgggcct
     9601 gcacgagccc cgctccggcg agcgcgcgca gggcctcccg tacggtcgag cggcccacgc
     9661 cgagggtctt ggccagcgcg ttctccccgg ggagccgggt gccgaccggc cactcgccct
     9721 gcgtgatctg cgcgcgcagg tgctcggtgg cctgctcgac gagagggctg gggcggagtg
     9781 agccgagcgg catggcggtg aacctctcag gttgtctgag gacctgtgtt gtgattagtc
     9841 tacccgcatg acgtcgtacg gtcgcctgct tcttggccgc cgcggcgggg cctgaccgga
     9901 ccggcacccc gccgcggtgg tcagggtgcc cgccggtccc ccgtcacgac ccagagggaa
     9961 gttcaccgtg tacgactgga accggcagcg ccccagcggc atgccgtatc accgctaccg
    10021 ccccgtccac gagcgcgtcg aggtgccgct gaccggccgc gcctggccgg cgcggcgcat
    10081 caccgaggcc ccgctgtggg tgcccgtcga cctgcgcgac ggcaaccagg cgctggccga
    10141 gccgatggac ccggaacgca agcgccgcat gttcgagctg ctggtcggca tgggtttcaa
    10201 ggagatcgag gtcggctacc cgtcctccag ccggctggac ttcgacttca tccgccacct
    10261 ggccaccccg ggcaccgtgc ccgaggacgt gaccgtcgtg gtgttcacgc ccgccaggag
    10321 cgagctgatc gagcgcacct tcgagtcgat cgagggcatg tcacgcgtgg tcgtgcacct
    10381 ctacacggcc accgccccca cctggcgcga ggtggtgctc ggccaggacc gggccgcgct
    10441 gcaccggatg atcagaagct ccgccgagca gatcgcccgc ctggccggcg accgggacgt
    10501 gcgcttccag ttctcgcccg aggtgttcaa cctcaccgag ccggactacg tcctggagat
    10561 ctgcaacgac ctgaccgccc tgtgggacgc ctcgccggac cggcccgtga cccacaacct
    10621 gcccgcgacg gtcgaggtgg ccacgcccaa cgtgtacgcc gaccagatcg agtacatgca
    10681 ccgccacctc gaccgcaggg acgccgtgat cctgtcggtg cacccgcaca acgaccgcgg
    10741 caccggcgtg gcctgcgccg agctggccgt gctggcgggg gcgcagcggg tggagggctg
    10801 cctgttcggc aacggggagc gcaccggcaa cgtggacctg gtgacgctcg cgctgaacct
    10861 gcacgcccag ggcgtcgacc cgatgatcga cctgtccgac atcgacgagg tgcgcagggt
    10921 cgtcgagcac tgcaaccgcc tgccggtgcc cgagcgccac ccgtacgcgg gcgacctcgt
    10981 ctacaccgcc ttctccggca cccaccagga cgccatcaac aagggcctgg cccaccacgc
    11041 caagcgggcc gccgacctgg gcgtgccgcc ggagcaggcg ccgtgggagg tgccgtacct
    11101 gccgatcgac ccggccgacg tgggccgcgg ctaccaggcg gtcatccgcg tcaacagcca
    11161 gtcgggcaag ggcggcatcg cgtacctgct gaacacccgt tacggcctgg agctgccgcg
    11221 gcggctgcag atcgacttct ccgcggtcgt gcagcgggcc accgacggca gcggtgagga
    11281 gatcaccgcc gagcagctct gggagctgtt ccacgccacc tacctggcgc cgggcgagat
    11341 cggcgcgctg gagggctgga gcacggtgga gaccgggccg ggcgtgcacg agttcaccgg
    11401 cacgctgccg ggcggccggc ggctgagcgg caccggcaac ggcccgctgt cggcgctgac
    11461 cgcggccctg gccggcgacg ggatcgacgt ggacatcctg cactactccg agcacgccct
    11521 cggccccggc aagggcggcc gggccatcgc ctacgtcgag gccaaggtga acggcaccac
    11581 ctgctggggc gcggcccagg acacctcggt cctgaccgcc tcggtgcacg cggtgctggc
    11641 cgccgtccac cgcgtcatct gatctaggat cgtcgtcatg ttcgaagcgg gtgcggtgct
    11701 cggcgtgctg gaggcgttgc ggaaggcggg ctgcgccgtg tgggtcgccg gcggctgggg
    11761 catcgacgcc ctcgtcggcc gggtcaccag ggagcacggc gacctcgacc tgctgcaccg
    11821 cgcggagcag gagccggccg tgatcgccgc cctggagtcc ctggggtacg ccgagcgcac
    11881 cgagggcgtc gtccccgggc ggcccgcccg cttcgtcatg accggccccg gcgggcggga
    11941 gctggacctg cacccgctgc acttccggcc cgacggctcc gcgctgcagc ggctcgacga
    12001 cgagggcggc gcgttcacct atccggccga ggtgttcgtc accggcgaga tcgagggcgt
    12061 gcgggtgccg tgcctgtcag tggcccagca ggtgagcttc caccagggtt acccgcccag
    12121 ggagcgcgac ctgctggaca tggcgcggct gcgcgcggcg tacgggatcg acacgcactt
    12181 ctgagcgccg ggcgctaccg ggcgtcggcg gcgaggtggg cggcgcactc gtcgcggtag
    12241 cgcagcgtgc gcgagcgcac cagcttcggg tccgacagca cggcccgcga caccgacggc
    12301 aggaccgcgt gccgtacgga cccgaacagc cgcgccacgt cggcgggggt ggccccctgc
    12361 gcgcccagcc cgggcgccag gatgggcccg ttcaggtcgt cgagcgagtg ctccagctcg
    12421 ggcagcgtgg cgcccatgac cactccgacg ggcccgaacg gcgcgtggcc cgcgttcgcc
    12481 gcggcggcgc cggccagcac ctggccggcc acgagccgct gcagcccggc cgcctccggg
    12541 ttcgacgtgc gggccagcac gaacacgccc gcgtcgttgg ccatcgccga ggtgatcgcg
    12601 ccctccaacg agccgaagcc caggtagggg ctgagcgtga cggcgtcggc ggccagcggg
    12661 ctgcccttgt cgaggtacgc ctcggcgtag gcggccatcg tgctgtcgat gtcgccgcgt
    12721 ttgacgtcga gcagcacgag cgtgcccgcc tcgcgcaggt cggcgatcgt ccgctcgagg
    12781 acggcgatgc cccggctgcc ccagcgctcg aagaaggccg actggggttt gaccacggcc
    12841 gcgacgtcgg ccaccgcctc gaccaccgtg cggcagaagc gctccagcgc cgcgggggag
    12901 tcgtcgaggc cccaggtgtg caggagggcg gggctcgggt cgatgcccac gcagagcggc
    12961 ccgcactcgt cgagcctggc tcgcaggcgg ctcccgaacg actcgttcat ctcagcgctc
    13021 ccctgggcga atggtcctcc ggcgacgata tggtacgcga gccgccgttg cctaaccggt
    13081 gcccctccga gtcttccgcg cgtggccccg gggtagatga gcagacatgt acgagatcgc
    13141 ccaccgggtg ctgacgctgc gcaccgatcc gccacgcgag gtcgtggtca cggtcggcgt
    13201 gccgttcgag gaaccgacgg gggagtggtc gtgcccctac cggatcgacg ggctggacgg
    13261 ctgggagcac gagcggaagg tctccgggct cgactcgctg gaggcggtcg agctggcgat
    13321 ggtgacggtc agggccgcgg tggcgggctc gcacgaggcc agggaggggt tgctggcctg
    13381 ggaggaggag ccggccgggc ggcgggcgcg cacggtgtac gtgagcgtgg accgggccag
    13441 gaacctcgcc tacatcgcca tgaagcacga gatcgtgccg ggtgaggcga tgcggcagtt
    13501 cgtggcggag gacatcgtcc tcgactacgg cgacgccggg cagctcctcg gcctggagct
    13561 cacggacgcg gcccggctgc tcccctcgga gctgcgcctc tagcgacgtg tcagcagcca
    13621 ccgccagcgc ggcagttcga gcaccaccgt gaccacggcc agcacggaga ccagcgcggc
    13681 ggcgaacgcg tgccacgcca cccacgccgc cgccacggcc gccaccacct ggaggaggac
    13741 gagcaggatc gtcacgaagc cgggcacggc gacgatcacg ttccgcttgt cgcccggggt
    13801 ggagaagagc gtgggcagcc cgatcaggac gatcaccgac agcacggcca gcgccaccga
    13861 gtgcggggcc agcgcccacg gggtcgcgac ccaggcgacc agctcggtgg cgaagcggaa
    13921 cacggacgcc gtgcggtcgt ccgggcgggg ggtcatgggg ggaacggtgg aggacacgcg
    13981 cgtaccctac agcggacctc tgaggtgttt catccggata tgtcgcgata atcgcttctg
    14041 tgagcagctt ccccagaatc gtggccaccg acctcgacgg caccctcctg tccgacgcgg
    14101 gcaccgtcac cccccgcacc aggcaggcgc tccaggcggc ccgcgcggcc ggcgccgaga
    14161 tcgtcttcgt caccgccaga gccccgcgcg gcgtgcgcgg catcgcccgg caggccggcg
    14221 tgtccggcac cgcgatctgc agcaacggcg ccgtcgtgta cgacctcgcg accgacgaga
    14281 tcacccacca gtatcccctc gacccgcgca ccgcccgcca ggtggcgcag gccctggccc
    14341 tggcgctgcc cggcgtcggc ctggccgtcg agacgggcag gaacatcctg gtggaggccg
    14401 cctacacccg ccggatcgag cacgacgtgg ccttctaccg cgaggtggag tcggtcttcg
    14461 acgaggaccg gcccatcgtc aagctgctcg ctctgtctcc ggcccacacg gcggacgaga
    14521 tgtacgcggc cgtggccgcc tcgatcggcg acctggccga ggtcacgtac tcgggtatgg
    14581 aagggctctt ggagatcagc gccgccggcg tcacgaaggc ggtcacgctc ggccggctct
    14641 gcgcggagcg gggcgtggag gccggggacg tggtggcgtt cggggacatg ccgaacgacc
    14701 tcgcggtgct gctctacgcg ggggccggtt acgcgatggc caacgcgcac ccgatggtgc
    14761 tgtcggcggc cggccaccgc accctgtcga acgacgagga cggcgtggcc gtggtactgg
    14821 agaacctcct cgccgcccgc tgaaacctga tgccccggtg cccgcccacc cccgcgggcg
    14881 ggcacgtacg gcgtcatgcg tcgtcgtccg acacgcgcga ggcgccctcg caggtggtgg
    14941 gcgacttgct gagcagcgga accaggccgc cacaggtgct caccggcagc gacacgggct
    15001 cgacgatctc gtcattgaag atgatcacgt cgccgatcag cgacgacgag ccctgcttcg
    15061 cgccgccgtc ctccgcctcg gcgaccgccc cggtgccgca gagcagcgcc aggacggccg
    15121 ccgggagccc cgcgaacgcg gcgccgcgta ccctcatccc gcgctccgcc aggaacggcg
    15181 gcacgccggc gggcgcccgc tcacgcggcc atccgctccg gctgcaactg acccggccgc
    15241 tcggcaccgc cggtgccgtg ctgcggccgg ccaccggcca tgatgcggtc gatggtggcc
    15301 agcgccagcg ccgagacgac gaaggtcaga tggatcaggg ttttccatat cagctctctg
    15361 tcggtgatgg tgggccgggc cgcgttgatg aagatctgca gcaggtggat ggaagagatg
    15421 ccgacgatcg ccatggccag cttgaccttc agcacgttgg cgttgacgtg ggagagccac
    15481 tgcggctggt cggggtggcc ctcgatgcgc agccgcgaga cgaacgtctc gtaaccccct
    15541 atgatgacca tgatcagcag gttggagatc atgacgacgt ccacgaggcc gaggacgatc
    15601 agcatgaccg cggtctccgg cgggtgaccg gtgaagccga ggtggaccag gtggagcagc
    15661 tccatcatga accgccacac gtacaccacc tgggcgacga tcagccccag gtacagaggc
    15721 gcctggaacc agcggctgag gaacatgatg tagccgacgc gcccggatct cgtccgtgac
    15781 tcggtcggcg agtccgccac ggacagtcgc gcgagtcgca ctacgacgtc agcaggttga
    15841 tgtgctggac gtaggtgctg atgtcgacgc ggggcggatc ggagccgaga ctgtcgaggg
    15901 tgatcggtgg tgcgccgccc gccagtgcga gggcggacag ggcggtgagg gcggccacga
    15961 cgcggacctt caacggaact ccttgctgct cttcggtttt ctgggaccgg gcggcgcgga
    16021 tctggcgcgc cgcccgcacc ggttgtcccg gtcgtcgagg ggtgaccttc gccggcggtc
    16081 tgcgcccggc gatcaggggg ccaggcagga caccccgggc atctcggcgg gcaggccggg
    16141 cgcggccggg tcgacggccc cgggcaggcc cgtggcgccg tgcgtgagac actcggcgat
    16201 caccatcgga tcgacgacgg cgtacgaggc gggcgcggcg agcacggtca ggccggccgc
    16261 gatgacggcg gcgccggcga tcctgcggac agtgaagagc atggaacctc ctgggtaacg
    16321 gtaatgaaca accctcgact agctacccag agtagtgatt tggtaacact cggctcaagt
    16381 aaagtgttgc gcgcactcca tgctcaggcg ggttcgtaac gatcctgggc ggccatgacc
    16441 tcgtcgccgt ggtcggccgc ccacgcgccg aacgcctcga tcgggccgag cagcgagcgg
    16501 cccaggccgg tcagctcgta ctcgaccctg ggcggcgcct cggcgtagac acgccgggcc
    16561 accaggccgt tgtactccag gcggcgcagc gtctcggtca ggaccttcgt gctgatgccg
    16621 ccgatctccg cgcgcagccg cccgggccgg cgcgggccgt ggcgcagcgc ccagacgacg
    16681 accgcgttcc aggtgttggc catcaggtcg aaggcgagtc tggcctggca gtcggcgagg
    16741 aacaacgcga ccctccattg ggcaccgaat ggtgcgtgtc ggaacttcta ccgtcccagt
    16801 aaagccctaa cggacggagg acggacaatg cggatcggga tcctgggcgc gggcggcatg
    16861 gcggacgccc tgggcacgca gtgggcacgc gccgggcacg aggtgacggt gagcgggcgg
    16921 gacctgagcc ggagcgcggc ccaggcggcc cggatgaccg ctgcggcggg cgctgaggtg
    16981 cgggccgcga gctacgcgga ggcgggcgcg ttcggcgagg tcgtggtggt ggccgtcagg
    17041 gaggaggggc tgctggacac gctccaggcc gccggcgcgg cgctgcgcgg caaggcgctg
    17101 atcgacgtca ccaacgccgc ccctctcacg tacgacctca cgcgctccca cgcccgcctc
    17161 atcggcgaca tcaccggcgg gcacgtggtg aaggcgttca acctgtgcca cgtggacgtg
    17221 tggcggatga cgccgcccgt cttcgacggc aggccgctgg cagtgcccct gtgcggcgac
    17281 gaccccgagg cgctggccgc cacccgcacg ctcgtcgccg acctgggctg cacccccgtg
    17341 gatgggggcg ggctcgaacg ggcggcgctg ctggaggcga cggcggcgtt catgatcggc
    17401 ctgtggttcg gcggcaccga cgcccaggcc atcctcccgc ccctggcctc gtcgggcgca
    17461 cacggatcct cctgaggggg cttgcggcgc ggcaccgctg ggggcgacgg gcggcgggtg
    17521 aggggcggcc ggcggccagg acgcgtgggc cgggcgaggc ggccggcggt gtgggcgcgt
    17581 ggcggtcagg acgcgtggag acgggtgaga cggccggcgg tcaggacggg tggcgggcca
    17641 ggtggtcggc gcggcggacc ggctccggga ggcggtagcg cggggtcagg cgcaggacct
    17701 ggtccgtggc gacgtccagc gagatgcggt gcccctgcga gacgtacacg ggcttgacct
    17761 cccgctgcgt ccgcagggcg cgccccaccg tggcgccctc gtgcacgatc ggcgtccacg
    17821 ccccccgctc cggccccggc ggctcgtgcg tgccgacgaa cggcgtcttg cccacaccca
    17881 gcgcgggcag cccggtcagc acgcccagat ggcaggccag gccgaagccg cgcgggtgcg
    17941 ccagcccgta cccgtcgcac accagcaggt cgggcgtcac cgtgagccgt tcgagcgccg
    18001 ccaccagcgc cggcagctcg cggaaggcga acaggcccgg cacgtacggg aaggccgcct
    18061 ccccgtgcgc caccacctcc tccaccggct ccagcgtgcc gccgtcgagg acgaccaccg
    18121 cggccgtcag cgcgtcgtcg ccgcggtagt gcacatccag cccggccacc agcgcgaacg
    18181 agtcgggccc cgacagctcg acctcgccac ggagccggtc ctggacggcc tccgcctcgg
    18241 cgacactgcc gggccacggg tgaagctgct tcacatgcac ccggcctaag gtatccccat
    18301 gcgcgaggtc ctggtgatcg tcggtccaga ggtggtggcg gacgccgaac tgctcggcga
    18361 gatcgcccgc cgcgagttcg ccgcgctcgg ggtggcgggc cggctcgtcc acgcccgcga
    18421 cgccgcccac gtgcgctctc tcatgcgtac ggaggacgtg gtcgtcgtcg tccccgcccc
    18481 cggccccgac gcccggaccc tgctccggca gccgcccggc agcggggtgg tggtgccggt
    18541 ggacatcgac cgcgtcccgg gcgcccgcca catccacggc cgcggcctcg cgggcctcgc
    18601 ctgggccatc cgccacgccg tccaccgcgc ccgccacccg caggtccgcc ggatccccta
    18661 cggcccgtca cccgagcagt ggggcgacct gtacctcccg ccggcgcccc aggcgggggc
    18721 ggcagtcccc gacgcagacc ccgccgagac gccccgcgcg acggaagggc gggcggagac
    18781 gcctggcgcg gcgggagagc gtgccgaggt gcccggcacg ggaaggcatg cggaggtgcc
    18841 cagcgcggcg ggcgggcgtg cggaggtgcc cggtgcggcg ggcgtgcccg ggcgggtgcc
    18901 ggtcgtggcg ctggtgcacg gcgggtactg gcggtcggag tgggcggccg acctcatgga
    18961 ggcgctgtgc gcggacctgg cggcgcgcgg gttcgcggtg tggaacctgg agtaccgccg
    19021 cccggacctg cacggctggg ccgcgacccg tcaggacgtc accgccggcc tggccgccct
    19081 ccacgccatc ggccccgcca ccccgactgg cccgaccctc gccgcccgcc gcgcgcagcc
    19141 ggggaatggg ccagacgcat ccgatcgcgc cgagccacgc aatgggccag acgcggctga
    19201 ccccgccgag ctacgcaatg ggccaggtgc ggctgaccgc gccgagctac gcaatgggcc
    19261 agacgcacct gaccgcgccg agccgcgcaa tggcccagac acgcccgatc gcgccgagcc
    19321 gcagccgccg tcggtcgcgc ctggcctggc cgtcccggag gcgccgtcgc tcgacctgga
    19381 tcggatcgtc gtggccggtc actccgcggg cgcgcagctc gccttgcgcg ccgtggccga
    19441 cggcgcccgg gtggcgctgg ccgtgtcgct ggcgggcgtg ctcgacctgg aacagacgga
    19501 ccgccgctgg ctcagccacg gcgcgatggc cgcagccctg accggcggcg aagcccctgc
    19561 acccgccctg gaccacggct ctctggacga gggggagttg ctcgcctcct cgcccctcct
    19621 ccgcctcccc ctgggcgtcc cgcagatcgt cgtccagggc cggggcgacg acgtcaacct
    19681 ggtcgacttc tcccgccgtt acgtcgccgc ggcccgtcag gcgggggacg aggtggcgta
    19741 cctggagctg cccggcgacc accaggacgt gatcaccccc ggcaccccga tctggcaggc
    19801 gacggccgcc gccatcacca gagtcgtcac cgccgtcacc tagacaaccc ccgccccccg
    19861 ccgtacgaag gagagatgga ggtctcgatc gtcggcgccg ggctggtcgg ctgcctgctc
    19921 gcctgctacc tggcccgccg cggccaccgc gtcaccctgt acgaacgccg ccccgacccc
    19981 cgggagcgcg gcccggaccg cggcaggtcg atcaacctgg cgatctcgcg ccggggcatc
    20041 gacgccttga gccggatcgg gctcgacggc aaggtgctgc acgcggcgct gccgatggcg
    20101 ggccggatga tgcacgggat ggacggcgcg ctcacgttcc agccgtacag cgcggaccgg
    20161 tcgcaggcga tcaactcgat cggccgcgcg gacctgaaca gggagctgct ggaggcggcg
    20221 agcgcgcagc cgggcgtgga ggtgcggttc gggtgccggt tgacgggcct ggacgagcgg
    20281 acggggcggt tacggttcgc gtcgggcgag gaggccgagg ccggggtggt gatcggcgcg
    20341 gacggggcgt acagcgcggt gcgggccagg ttgcagcagc tcccgggcgt gagcttcagc
    20401 caggagtacc tggactacgg ctacaaggag ctgtcgatcc cgccgcagga cgggcggttc
    20461 gccctggatc cgggggcgtt gcacatctgg ccgcgcggcc gttccatgat gatcgccctg
    20521 ccgaaccagg accgctcgtt cacctgcacc ctgttctggc cgcacgacac gctcgccgcg
    20581 ctcgacaccc cgcagcggat cagggcgtac ttcgccgagc actaccggga cgcgttcggg
    20641 ctgatgccgg acctggtgcc ggacttccgg ggcaacccgg tggggcatct ggtcacgatg
    20701 cgctgctcgc cgtggcacgc cggcggcggg gacgcggtgg tggggctggt cggtgacgcc
    20761 gcgcacgcga tcgtgccgtt ctacgggcag ggcgccaact gcgggttcga ggactgcgtg
    20821 gagctggacc gctgcctgga cgaggcgggc gacgacttcc cgagggcgct ggagctgttc
    20881 gagcggcgca aggcggacac ggatgtgatc gcccggctgg cgctggacaa cttcgtcgag
    20941 atgcgcgaca aggtgggctc gcgggtgttc ctggcgggca agcggctgga gcacgcgctg
    21001 gagcgggtgc tgcccggtta cgtctcgcgt tacgagctga tctcgttctc gacgacgccg
    21061 tactcgcagg tggagcggcg ggtggcgcgc cagcggcggt tggcggtggc ggcgggcgcg
    21121 gcgctggtgg cgctcgggtt cgcggcgcgt cgcggccggg gtctggtgcg tacgcccgag
    21181 gccgactgac actgtgggca tgctgtcgta ctccagcgcc accgccgaca ctccgctcct
    21241 gggcgagacc atcggcgaga acctcgaacg caccgtggcc cgcttcggcg accgggaagc
    21301 cctcgtggac gtcccctcgg gccggagatg gacctacacg cagctcgacg cggacgtcga
    21361 cgacctggcc agggccctgc tggcgagggg catcgcgaag ggcgacaggg tgggcatctg
    21421 ggcgcccaac cgggccgaat gggtgatcgt ccagtacgcc accgccaagg tcggcgcgat
    21481 cctggtcaac gtcaacccgg cctaccgcac gcacgagctg cgttacgtcg tcgagcagtc
    21541 gggcatgcgg ctgctcatca gcgccctgtc gcacaagggc agcgactacc gggccatggt
    21601 gacggaggtc ggcttctccg acgtcgtcta cctggacgac ccgagctggg agcggctgac
    21661 ggaggtcaag gcggacccgg cggccctgcg cgcccggatg gcggagctgg ccttcgacga
    21721 cccgatcaac atccagtaca cctcgggcac gaccggcttc ccgaagggcg cgacgctgtc
    21781 gcaccacaac atcctcaaca acggcttctt cgtgggcgag ctgatccact acaccgaggc
    21841 ggaccgggtg tgcctgccgg tgccgttcta ccactgcttc ggcatggtga tgggcaacct
    21901 gggcgccacc tcgcacggct cgtgcatcgt catcccgtcg ccgggcttcg acgccgaggc
    21961 cacgctgcgc gcggtggagg aggagcggtg cacgtcgctg tacggggtgc cgacgatgtt
    22021 catcgccgag ctggcgctgg ccgccaagtt cgacctgtcg tccctgcgta cgggcatcat
    22081 ggcgggctcg ccgtgcccgg tggaggtgat gaaacgggtc gtcggcgaga tgaacatggg
    22141 cgaggtcgcc atctgctacg gcatgaccga gacgtcaccg gtgtccacga tgaccaggtc
    22201 cgacgacgac ctggcccgca ggacggagac ggtgggccgg gtgatgccgc acgtcgaggt
    22261 gaagatcgtg gacccggaga cgcggctgac ggtgcccagg ggggagccgg gcgagctgtg
    22321 cacgcgcggc tactcggtca tgctcggcta ctggaaccag ccggacaaga cggccgaggc
    22381 catcgacgcg gcccgctgga tgcacacggg cgacctggcc accatggacg agcacggcta
    22441 cgtcaacgtg gtcggccgga tcaaggacct catcatcagg ggcggggaga acatctaccc
    22501 gcgcgagatc gaggagttcc tgtacgggca tccggacatc gccgacgtgc aggtcatcgg
    22561 ggtgcccgac gagaggtacg gcgaggaggt catggcctgg gtgatcatgc ggcccggcac
    22621 ggagccgctg acgcccgagc ggctcaggga gtactgcgcg ggcaggctgg cgcacttcaa
    22681 gatcccccgg tacgtgcacg tcgtggacgc gttcccgctc acggtgaccg ggaagatcag
    22741 gaaggtggag atgcgggagc gttccgtcga actgctcggc ctgcgggacg cggcgggcat
    22801 aaggaacgcc tgaacgggtg cgagcggccg tacggaacgc ctgagcgggt gcgaccggcc
    22861 ggtcaggcgg cgccgctcac gccggtggcc gtcccggcga ctgtcccggc ggtcgttccg
    22921 gcggctgttc cggcggtggc gagtgcggcg aaccggccga tcaccgtgcg ccagaccggc
    22981 gtggagaccg gctcgtcggc caccgcccgc gcgtacacct cgtcagggtc gaacccctcc
    23041 acccgccact cccggatgcg cgccggcagc acctccggat ggaactgcac gccccacgcc
    23101 cgctccccca cccggaacgc ctggtacggg caggcgccgg tctcggccag gtgcgcggcg
    23161 ccgccgggca ggcgggtgac ggcgtccttg tggtgctcga tcgcgggcac caccggcggc
    23221 aggccgtgga agagcgggtc ggtggccgcc tcgggcctga tcgtgacggg caggctgccg
    23281 ttctccggcg tgcctgagtt ggcgcggacc tcgccgccgg cgacctgggc gagcatctgc
    23341 ccgcccaggc agatgccgaa cacgggcacc cccgcggcca gcgcctgctc catcaggcgc
    23401 cgcgcgtcgc gcagccacgg ggcccgctcg tcgtcgccgg gcaggtagcc gccgccgagc
    23461 atgatcatgg cgtcgtggcg caggccgccg ggcaggggcg cgcccgcgtg ggcgggcacc
    23521 acgtcgagcg tcaggccgcc ctcctccagc catccggcca tccggctggg gccgccgctc
    23581 gtgctgttct ggatgacgag gacgtcagcc atcgtgggcc tcctcctggg ggtcgtgcgg
    23641 ccggttcgcg gccctggcgg tgtggctgag cagcagggcc gtggtgacgg ggccgacgcc
    23701 gccgggcacg ggggtgagcg cgccggccac gttcgagacc gcggcgaagt cgacgtcgcc
    23761 ggtcagcccg ccgtcgtcgg tcgggttggt gccgacgtcg atcaccaccg cgcccatcgc
    23821 gacgtgcgcg gccccgatca gcccggcccg cccggccgcc gcgaccagca cctcggcctg
    23881 cgaggtgacg gcggccaggt cgcgggtacg cgagtggcag acggtgaccg tggcgtgccg
    23941 gtcgagcagc aggtgcgcca gcggcttgcc caccaccgtc gagcggccga cgaccacggc
    24001 ccgccgcccg gccagctcca cctcgtagtg gtcgagcagc gccagcacgg ccgccgccgt
    24061 ggcgggaggg aaggcgggca gcccggccgc cagccggccg agcgagagcg ggttggcgcc
    24121 gtcgacgtcc ttgcccgggt cgatggccgc ggccagctcc tgcgcggagg cgccgggcgg
    24181 cagcggggtc tgcagcatga ggccgtgcac ctgcgggtcg gccgacagcc gggccagcgt
    24241 ctcgcggatc cggccgggcg ccgcctcggg gcccaggtcg accacgtcgc aggcgatgcc
    24301 gacgccggcc gcggccttgg cgatggagcg gacgtaccac aggctcgcct cgtcggcggt
    24361 ggccacgacc acggccagcc gcggctgcgg gcccgcggcg gcctcggcct gcgtgcgcgc
    24421 cctgatcgcg gcggccagat ccttgcccgt cagcgtcttc aagagatctc ctcgcgtacc
    24481 tcggcggtca cccagtctgc cctggcgacg gccgcgtcca cgccggagat ccggatgttc
    24541 agctcttcgc gtacccgctc gtccttgatg ccgcgcaggt tgatctcgac gttcacccgg
    24601 gccgtggtga gtgcggcgcg ggcggcgtcg gcggcggcgg ccacgtcggt gacgacgttg
    24661 cggttgccga tcggcagcag cagctcgcac agctcgacca ggcgcgtggc ggtctcggcc
    24721 acccgagcgg gcggctcggc ggcgccggcc agcgcgcggg cgatggcggc gctgcgctcc
    24781 tcgcccttgg gcagccggta ggcgtcggtg accgcggtga acgccgccgc gtcctcctcg
    24841 gccagccgca gcgcccgcgc ccgcagcgag tccgtctccg cgatcacggc gacgacggtc
    24901 tcggcgtgct cggtgtactt ctcgccggtg gtgtagcggg ccaccatgcc gagcagcgcg
    24961 gcggcctgcg ccgcgtgcag ggccgccgtg gcgccgcccc cgggcgcggg cacccggtcg
    25021 gcgagctggt cgaggaagtc gacgatcttc aagtcgcgca tggccgcatt ctgccaggcc
    25081 acgcgcggct cattcgcggt acatcggccg cgtggtgtcc tcggggctgt tgtacggcgg
    25141 caggtacggc gactgcgacg gcgacgccgt gccccaggcg gactcgtagg cgacgggctg
    25201 ctcggccagg tcgcgcaccg agccccgcca gcgcgacggg aacagcgaga cgaccagcag
    25261 cgtcaccccg accacggcca gcagcccgga gtgggccgtg gtggtgaagc cgctgcgcag
    25321 cacgcccggc agcaggtcca ggggcagcag ccggacccgg gtgaacatct ccgcgaacgg
    25381 caggaccccg gcggcggcga aggccaggcc gccgagcagc gaggccacgg gcgacaggcg
    25441 cgagccggcc aggaaggcca ggacgaccgc cgtcgcggcg agcacgccga ccgcgaccca
    25501 ggagatgcgg aacgcctgct gcgcctgaag ggtgaggtcg ccgacgccgt accagaggcc
    25561 ggcggcgacg aggggcggga ggagcagtcc cgcgaccact cccagagcgt gacgggcacc
    25621 gtttgacatg attaaccccg tttgtttggc tctgtcccaa cctactcgcc ggggtcggtc
    25681 agcggggcgt ggtcttggag tccagccacg tgttgatgtg cttggtgaag ttcctgccgg
    25741 tgtgctcgtt gatccacttc acgaacgcgg ccctgtcctg cgtggtgttg cggtgctcct
    25801 gcggccacgc cctggtcatc gcccagaact tcttgtcgcc gagccgcttc ctgatctcgt
    25861 gcagcatgat cgccgggctg tagtagacgt tgctctgccc gaacgcgtca cgccggtact
    25921 ttccgggcgg gccgttctcc cggcgcagct cggcgtcgta ggcgcggatg ttggagatga
    25981 acgcgtcgat cgtgccgtcc tcgtggtcgg cgtaccactg catctcgaag tacatcgcga
    26041 agccctcgtt catccacatg tcccgccagg tgcgcggcgt gaccgtgtcg ccgaaccagt
    26101 ggtgcgccag ctcgtgcgcc accaccgacg gctccatgta gcgcgggccg agcgccacca
    26161 tctgctgcgt ctccatgccg gagtcgctgg tggccaccag ccccgcgctc gggaacgggt
    26221 acgggccgag cttcttctcc agccagcgca ggatcgccgg catccgccgc gcgaccggaa
    26281 gctgcttgcg cacgtcctgg ggccggatcc agtacgtgat cgggatcccg cgcggcccct
    26341 tgtccgtgaa catccggaac ttgtccgccg cgaacaacgt caggtaactg gccacggggt
    26401 cggtcgactg ccagcggaac gtgctcgacc tcccctcggt ggtcttgccc ttgtatgtcc
    26461 cgtgcgcgac ccccgaccac cccttcggca ccgtgatcgc cacgtcgtac agcgcctcgt
    26521 ccgacggatg gtcgttgacc gggaaccacg tgaacgcccc gaacggctcc tgcagcgccc
    26581 acgccctgcc cccgccgccg atgcggaagc cgagcatgga gatgtcctcg cgccgctgct
    26641 tggcgtccac gggcggctct gccaagattc ctgtggtgac agaaggtgct gttccatcca
    26701 cactccgctg ctctggatga gaccgtgaac ggtgtgcaac cgtgacatgg tgaacgtgct
    26761 cttcccgcac ctggccgcgg tggagatcga gcaggtggat cgtcaggacg gccagatccg
    26821 ggtggtggcc cgcacgcgag gcgatccggt gtgctgcccc tcgtgcggga cggccacggg
    26881 caaggtgcac ggctatcacc ggcgccgcct ggccgatcgc ccggtggacg ggctgcccgt
    26941 ggtgatcgag ctgaggttac gacgcctggt gtgcatcaac ctggactgcg cgcggcagac
    27001 cttccacgag caggtgccgg gtctggccgg ccgctacgga cgtcgcacgg cgggcgcgac
    27061 ggcgctggtg atcgcatgcg cgctggcgct ggctgggcga gccggcgcat ctctcctggc
    27121 cacgatcggg ctcctgctca gccgcaccag cgtgctgagc accttgatgg cactgccgga
    27181 gccgccgtcg accgtcccgg cggtgatcgg cgtggacgac ttcgcgatca agcggggtca
    27241 gcggtatgcc accatcatca tcgatgccgt cacccatcgc tgcctggacg tgctgcccga
    27301 tcggctcggc gtcaccttcg cccactggct gcaagcgcat cccggagtcc agctcatctg
    27361 ccgggaccgc tcggccgcgt acgcggccgg cgcccgcgac ggcgcgccgc aggcggtgca
    27421 gtgtgccgat cgctggcacc tgctcaacaa cctcagcgag gccgtcgaga aactcgccct
    27481 ggcccaccgg ggctgcttcc gcgacatcgc caccggccag ggccgcgacg aaggccccac
    27541 cgtacggcgc acccgcagcc ggtatgcggc catccacgcg ctgctcggcc agggcgtgac
    27601 gaacaacgag atcgcccgcc ggctccacct cgccttgaac accgtcaaga agtacgcccg
    27661 cgccccacac gtcgagcagc tgatcggcgg ctcgaaacgg ggtgccacgc tggtcgaccc
    27721 gtttcgtgac tacctgcgca gccgccgagc cgccgaaccc ggcgtgaccg tgtgggccct
    27781 gctgcgggag atcaagtcga tggggtacca gggcggctcc acgctgctgt atcgctacct
    27841 gggccaagga cgcgccgagg acgctccggc gccgccctca ccccgccgcg tcgccagctg
    27901 gatcatgacc gacccggccc acctcagccc cggccgcacg acccggctgc aggaagtact
    27961 ggactgctgc ctggagctga agcaggccac cgagcatgta cgcaccttcg ccgacctgct
    28021 cacccagcgc cagggacacc ggctggacga ctggatcgcc gacgttcgcg ccggcgatct
    28081 gcaccccttg cgctccttcg ccgaaggact gctcatcgac cacgacgccg tcgtcgccgg
    28141 tctcaccctg ccctacagca acggccccac agaaggcgtg atcaacaaga tcaaactgct
    28201 gaaacggcag atgtacgggc gagccggtct ggccctgctc cgaaaacgga tacttctcac
    28261 catcgctagt aattgagcgt taccacggga atcttggcag agccccacgg gcttcggccg
    28321 gccgtggtag cgcacggtca cgaccgtgcc cgcgtcggcc tcgatcggct ccggcagcgg
    28381 gacggtcaga tcgtcgtact tgcgggtcgc ccgcacgcgc gtgccgtcga ccgtgacctc
    28441 gtccactttg agcgcgcgcc cgaagtccag cttgacccgg ttgatgggcc gggcggcccg
    28501 caccgtgagc ctggccgtgc cggtcagcgt gcgggtgccc ggcttccagt ccagcgccag
    28561 gtcgtagtgg agcacgtcga tcgacgggtc gccgtaggcc gggtagacgg ggtcggcgac
    28621 cgggcgcgag cggcccagct cgtacgcggc caggtcgacg gcggggcgct gccgctcgac
    28681 cgggctcggg gtgagagacg tgaccgccgg cttcggtggc ggcgccggcg cgctgcaggc
    28741 cgaaacggcc aggatggcgg acatcagggg taaaaggggc ctccgcattc gcgtcaacgt
    28801 agtgacggcc gtgcgaggat gacaacgctt tttcccgttc cgtaatcggg aatgcggcac
    28861 ttcctgaaat gtcaggacca tttctgaaag gtcgctgtga aggcacggga aggtctttgc
    28921 cccggccggt cccttgggca tcgtgggccg catgagatcc gcgatcctga agaccgcgct
    28981 cggcagtgcc atgctcgtcg tcctgctcgg cggggtgccg gcgcaggccg cgacgaagcc
    29041 cgacacgttc ccgctgccca acgggttcca gccggagggc atcgcgatcg ggggccgcta
    29101 cgcctacttc ggctcacgcg ccaccggtga catctaccgg gccgacctgc gcaccgggca
    29161 gggcggcgtg atcagcaagg ggccgggcac gccgtcgctc gggctcaaga ccgacggccg
    29221 cggccggctg ttcgtggcgg gcggcaacgc cggcaacgcc cgcgtgatcg acctgcgcac
    29281 cggcgcggtg ctcaagtcgt accagctcgc caccggcacg tcgttcgtca acgacgtcat
    29341 cctcgccggc cgggcggcct actacaccga ctccgccaac cccgtcctct acaagctgga
    29401 gctcggacgc ggcggcgcgc tgcccgccga ggccgtgaag atcccgctca gcggcgcgat
    29461 ccagtacacg acgggcaaca acgccaacgg catcgccccg agccccgacg gccgctcgct
    29521 gctgatcgtc cagtccaaca cgggcaagct gttcgaggtg gacccgtcct ccggcgtcac
    29581 caccgaggtg gacctcggcg gcgagtcgct ggtcaacggc gacggcctgc tcctggccgg
    29641 ccgcaccctg tacgtcgtcc agaaccgcct caacaccgtc gccgcgatcg ccctgacccg
    29701 cgacggcgcc tccggcaagc tcatcaggcg gctgaccgac gaccgcttcg acgtgcccac
    29761 caccgtggcc gcccacggcc gccgcctcta tctgcccaac gcccgcttca ccaccacccc
    29821 gacgcccgac acgacgtacg acgtggtgag cgtcaagccc tgacgcgccc gcccctactt
    29881 cttgatcgtg tacgagtccc cgtacacctt ccaggtcagc ggcgggttca ggtcgaggtt
    29941 gccgttcttg aggaacaccc gctgcatcgt gtcgacgcgg gtggtgtcct cgtgcgcgtc
    30001 ctcggccttc atcgccgtct tgcgggcgtc gaggaacgcg ttcaggtacg tcacctcgtt
    30061 cccgccctgg gccggcggct tggccttgcc cagggcggcc ttcctgatgc cgccgaagct
    30121 cagcttgtcg ttgccggggc cgtgcatgac catggcgtcg tagtagacga actggcccag
    30181 cgcccgcagc ccgtccttct gcgcctgcgt gacggccggg ttgaagtaga cgcggtcgcg
    30241 ctcgtcgttc tgggcctgct ggaagaccgg atccttggcg gccgtcttcc agtccttcgg
    30301 gaagttcggc tccaggccct tgtgggagtc ggtgccgttc accttgcgca gggccggcag
    30361 gtacttcgcg aggacgttgt ccggcttgcg ctcggtgtag agctcgacca gctccagcat
    30421 gtcgccggtg ccggagcaga agccgatgat gcccgccgtg tagccgcgct cgtccttgat
    30481 gtcctcgatg tagccgtact gggccttcca gtcgagcgag gagttctccg cgctggacac
    30541 cagccgcatg gcgatgtcct tcttgtgcgg gtcggtgaga gccggcgagg agacggtgag
    30601 ggagagggcc aggagcgtgg cggtcagcac aatacgtctc cgttcgttag gaaaggttcc
    30661 taacggacca tactcctgaa gcccgccctg cgggacgaaa actactcggt ccggcgaagc
    30721 gccgcgagct gctgctcgaa cggcacgacc tcctccacgg tctcctccgc acgcggagcc
    30781 cggtgcagca gcaggtccgc cagctcctgc gcggcacggc cgatgcgctc cccgagcccg
    30841 tcggtgaacg cgtcccggcc gccgccccag tcctccgccg ccgcgtacac ggccgtcggg
    30901 acgaccaccg cccgcaggta cgcgaacagc ggccgcaacg cgtgctccag ggccagcgaa
    30961 tgccgggcgg tgccgccggt ggccgcgatc agcaccggct tgcccgtcag cgcggtgttg
    31021 tcgagcacgt cgaagaacga cttgaacagg ccgctgtacg agccgctgaa gatgggcgtg
    31081 accgcgatca gcccatcggc cgccgtcacg gcctcggcca cctcgcgcag gcgggtgttc
    31141 gggaagccgg tgacgaaggc gttcgcgatg tccacggcca ggtcgcgcag ctccaccacg
    31201 cggacctcca cctccgcccg ctgcgccacc gcctcggcca ggcggtcggc gagcaggcgg
    31261 gtggaggagg gctgcgtcag ccccgccgtg acgacgacga gcttcatggt tctccttcga
    31321 ggacgtgctt gtcgggtggg tcaggcgccg acgggcgctt cgggagcgtc ctcgacggcg
    31381 ttcttggcgg cgttcttggc ggcgagcagg gacgcgtggg tcggcgcgtc gggcacgtcg
    31441 gccgggcggt ccttggcgaa ctccttgcgc agcaccggca cgacctcctc cccgagcagg
    31501 tcgagctgct ccagcacggt cttcagcggc aggcccgcgt gatccatgag gaagagctgg
    31561 cgctggtagt cgccgaagaa ctccctgaac tccagcgtcc ggtcgatcac ctgctgcggg
    31621 ctgcccacgg tcagcggcgt ctccgccatg aactcctcca gcgacggccc gtgaccgtac
    31681 acgggggcga cgtcgaagta cgggcggaac tcgcgcaccg cgtcctgcga gttcttgcgc
    31741 atgaacacct gcccgcccag ccccacgacg gcctgctccg gggtgccgtg gccgtagtgc
    31801 gcgtaccgct gccggtagag gctgatcagc cgcatgaagt gctccttcgg ccagaagatg
    31861 ttgttggcga agaagccgtc gccgtagtag gcggcctgct cggcgatctc ggggctgcgg
    31921 atcgagccgt gccagacgaa cggcggcacc ccgtcgagcg ggcgcggcgt gctggtgaag
    31981 ccctgcagcg gcgtacggaa gcggccctcc cagtccacga cgtcctcgcg ccacagcttg
    32041 tgcagcagcg cgtagttctc gatcgccagc gggatgccct ggcggatgtc ctgcccgaac
    32101 cacgggtaca ccgggccggt gttgccgcgg cccagcatga ggtccacccg gccgtcggcc
    32161 aggtgctgca gcatggcgaa gtcctcggcg atcttcaccg ggtcgttcgt cgtgatcaac
    32221 gtcgtggcgg tcgacagctg cagccgctcg gtcctggccg cgatgtagcc gagcatcgtc
    32281 gtgggggagg acggcacgaa cggcgggttg tggtgctcgc ccgtcgcgaa gacgtcgagc
    32341 ccgacctcct ccgccttgag cgcgatcgcc accatcgcct tgatccgctc gtgctcggtc
    32401 ggggtccggc cggtggtggg gtccgtggtg acgtcgccca cactgaagat tccgaactgc
    32461 actttagtca ccaaccctga ctgttgaatc tttgacggct atggtagcgt ccgcaccccc
    32521 tcagatattc caccacgcac cagacgtgct gcgagcgtgg gaaaggtggc gatcggggcg
    32581 ggcggggaag gctccggccg tcgggtggtc aggcgtgccg gcgggcgcgg aaggccgcgg
    32641 ccttggcgcg gttcccgcag ccgcgcatgt cgcaccagcg gcgcgtgcgc cggtgggagg
    32701 cgtcgatgta gagccgcgtg cagggatccg cctcgcactc cctgatcagc ccggcctgcg
    32761 gcccgccgag cagctcgacc gccgccctgg ccgtactgga cagcgccgcc cgc
//
