LOCUS       NZ_CP017717            33831 bp    DNA     circular CON 03-MAR-2024
DEFINITION  [Actinomadura] parvosata subsp. kistnae strain ATCC 55076
            chromosome, complete genome.
ACCESSION   NZ_CP017717
VERSION     NZ_CP017717.1
KEYWORDS    RefSeq.
SOURCE      [Actinomadura] parvosata subsp. kistnae
  ORGANISM  [Actinomadura] parvosata subsp. kistnae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 13047416)
  AUTHORS   Nazari,B., Forneris,C.C., Gibson,M.I., Moon,K., Schramma,K.R. and
            Setedsayamdost,M.R.
  TITLE     Nonomuraea sp. ATCC 55076 harbors the largest actinomycete
            chromosome to date and the kistamicin biosynthetic gene cluster
  JOURNAL   Medchemcomm (2017) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13047416)
  AUTHORS   Nazari,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) Chemistry, Princeton University, 20
            Washington Road, Princeton, NJ 08544, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUN-2015
            Assembly Method                   :: Celera Assembler v. Jun 2015
            Assembly Name                     :: SmrtPipe 1.87.139483
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 13:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 12,000
            CDSs (total)                      :: 11,919
            Genes (coding)                    :: 11,783
            CDSs (with protein)               :: 11,783
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 36 of 136
            Pseudo Genes (incomplete)         :: 98 of 136
            Pseudo Genes (internal stop)      :: 10 of 136
            Pseudo Genes (multiple problems)  :: 6 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:57:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 688006
            Orig. end                         :: 721837
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017717.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..33831
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAPAA"
                     /region_number="3"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..33831
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..33831
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[15000:18831](+)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      15001..18831
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     misc_feature    complement(74..88)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.19"
                     /tool="antismash"
     misc_feature    75..89
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.66"
                     /tool="antismash"
     gene            134..1567
                     /locus_tag="BKM31_RS03080"
                     /old_locus_tag="BKM31_03055"
     CDS             134..1567
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131825.1"
                     /locus_tag="BKM31_RS03080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03055"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_222107501.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.8e-45, bitscore:
                     154.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIFDVVVIGAGPVGENVADRTAAAGLDTVIVEAELVGGECSYWA
                     CEPSKALLRPVLLHAEARDMPGIDPGPLDVEAVLRHRDRMSSGWDDRPQVRWLEQAGIT
                     LIRGHARLSGPRMVEVTGADGETLRLAARHAVAVCTGSRPALPPLPGLAALRPWTSREA
                     TSATRVPPRLAVVGGGVVAVEMATAWQALGSQVTLLVRESGLLPRMERFAADLVADALR
                     ASGVDLRLDTTLTAATRDTDVRLTLSDGQVLHADELLLATGRAPRTDDLGLETVGLRPG
                     SRLPCDDTYTVPGVPGDWLYAVGDVNERALLTHQGKYQARIAGTVIADRARDQPLDRGP
                     WSRHTGTADQVAVPQVLFADPEIACVGLTTADAARLGREADVVDYDLGLVAGAHQHSPA
                     YRGRARILLDPARGTLLGATFAGRGVAELLQSATFAITGEIPLERLWHAVPAFPTLSEV
                     WLRLLETHRDTAVPLRSGR"
     gene            1584..1907
                     /locus_tag="BKM31_RS03085"
                     /old_locus_tag="BKM31_03060"
     CDS             1584..1907
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS03085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_03060"
                     /product="hypothetical protein"
                     /protein_id="WP_080036680.1"
                     /transl_table=11
                     /translation="MEWFFLPWTFMAYLTAGFDPAAPPRTERHGYEPPGPAEKWMIETA
                     YETVAAENRCTRCGAPLGRPRLRADAWPVRVAARCRGTARHRHRAAVFRTPDGLHTHPL
                     VRA"
     gene            2138..2578
                     /locus_tag="BKM31_RS03090"
                     /old_locus_tag="BKM31_03065"
     CDS             2138..2578
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073438.1"
                     /locus_tag="BKM31_RS03090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03065"
                     /product="VOC family protein"
                     /protein_id="WP_230465970.1"
                     /transl_table=11
                     /translation="MKLEVVVLPVSDVDRAKDFYTRQLGFRLDADFPINDGYRIVQVTP
                     PGSACSIIFGDGVSDSAPGSAEGLHLIVADIEQAVKELVGRGVEVTEPFHDATGAFHHA
                     GGRERVSGAHPQRASYGSFAAFADPDGNGWILQEITVRAPGR"
     misc_feature    complement(2626..2640)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            2631..3320
                     /locus_tag="BKM31_RS03095"
                     /old_locus_tag="BKM31_03070"
     CDS             2631..3320
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (5-127). E-value: 6.3e-09.
                     Score: 27.7. Matches aSDomain:
                     nrpspksdomains_BKM31_RS03095_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="BKM31_RS03095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03070"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_080036682.1"
                     /sec_met_domain="PF00561 (E-value: 2.2e-05, bitscore: 23.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.9e-21, bitscore:
                     75.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNKGTLLLVHGAWHSPSCWDRLVPELEERGWRTSTVDLPSTWGD
                     PQVGMYDDARAVRERLLALEGPVTVLAHSYGGVPVSEVAETVPNVRRLVYLAAHMLEAG
                     EAVITPLGGPWFPEDAELLPAPDQPIETLYHDVPAAWAQAAVARLRPQSARAFTERQTR
                     ASWRALPSALIVCDDDRIMPELFIKRQLTMTEVVRHLPGDHSPFLSRPGELAGLVDEVT
                     AALPARG"
     aSDomain        2646..3011
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS03095_Abhydrolase_1.1"
                     /evalue="6.30E-09"
                     /label="BKM31_RS03095_Abhydrolase_1.1"
                     /locus_tag="BKM31_RS03095"
                     /protein_end="127"
                     /protein_start="5"
                     /score="27.7"
                     /tool="antismash"
                     /translation="TLLLVHGAWHSPSCWDRLVPELEERGWRTSTVDLPSTWGDPQVGM
                     YDDARAVRERLLALEGPVTVLAHSYGGVPVSEVAETVPNVRRLVYLAAHMLEAGEAVIT
                     PLGGPWFPEDAELLPAPD"
     gene            3362..4564
                     /locus_tag="BKM31_RS03100"
                     /old_locus_tag="BKM31_03075"
     CDS             3362..4564
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="BKM31_RS03100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03075"
                     /product="cytochrome P450"
                     /protein_id="WP_222107500.1"
                     /sec_met_domain="p450 (E-value: 2.8e-19, bitscore: 68.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHGEPAAGTVVDLDRSFFQDPHPVYRRVREAGPVLPALAHRRLR
                     VWLVTRYAEARELLNDPRLAKDSAGAMELFPPGTAGPYASSLSAHMLNSDPPDHTRLRR
                     LVTKAFTAKTVSRLRPRIEQITDGLLDGMAEAGELDLIEAFAFPLPIAVICELLGIPAA
                     DHDVFRTWTAPFVAASSAEEMREAHAWMLAYLTDLVAAKRAVPGEDLLSELVHISDEGD
                     RLSRDEVVSMAFLLLVAGHETTVNLIANSVLALIGAPAQLAALRADPALLPGAVEEFLR
                     FDGPINIATLRFTTEPVRVGDVEIPADEFVFISLLAANRDPARFPDPDRLDVTRPGGGH
                     LAFGHGIHYCVGAPLARLEAQIAIGRLLARFSGIELAAPVLQWRASTLIRGPHTLPVRV
                     R"
     gene            complement(4608..5780)
                     /locus_tag="BKM31_RS03105"
                     /old_locus_tag="BKM31_03080"
     CDS             complement(4608..5780)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075699.1"
                     /locus_tag="BKM31_RS03105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03080"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_222107499.1"
                     /transl_table=11
                     /translation="MMRETGLMTSHEIVHGTVAAGFEDVRRAFADIAAGEPGLGAQLAV
                     RHHGRPVVDLWTGPEVTGDSLLALYSSGKGAAHLVVALLVQDGTLELDRRVAHYWPEFA
                     AAGKGEITLRDLLAHRAGLIGVPGGFSTAELADDRLLARRLAGQAPYWRPGSGYGYHAF
                     VIGALTGEVVRRATGRSLQEVYDERVRVPYRLDFFLGLPEDEEPRYLPVQPLAPEQRGA
                     AGPPAPDSLLGIAFNLNAARPTDLVEFANDRHVRALGPASSGSVGNARGLAKLYAAAIG
                     PVDGRPALLEPATLTAFTRPHTPGVDLVTGERDHFLLGFEALGARYPGLGADAFGHSGA
                     VGAQSFADPGSGIAYSYTRRRFTAGGGGAPENRLLIDAVMRAAAASDGRP"
     misc_feature    complement(5826..5843)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.04"
                     /tool="antismash"
     gene            5867..6493
                     /locus_tag="BKM31_RS03110"
                     /old_locus_tag="BKM31_03085"
     CDS             5867..6493
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025605.4"
                     /locus_tag="BKM31_RS03110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03085"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_080036684.1"
                     /transl_table=11
                     /translation="MTTTSRRVPTGERAARKRAAIVRAARRQFLEHGFGAGMDHIAAEA
                     GVSKVTVYNHFAGKEELFTEVVSDALEQALGQTMRAMNERLRTGDDLRDVLCATAREWV
                     EGIAQPDVLALRALITAEARRFPELGRLWRRHGPDRFAEPLATALAARDDLDIPRMELA
                     IVQFYALVLYPHIVHSAYGDRLDPGFTDELITTGVDMFLKYYRKR"
     misc_feature    6584..6598
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            6591..7370
                     /locus_tag="BKM31_RS03115"
                     /old_locus_tag="BKM31_03090"
     CDS             6591..7370
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="BKM31_RS03115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03090"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_230465971.1"
                     /transl_table=11
                     /translation="MTIIDAVAELEGQLANTRDYWLGWGSADRCDGELTLYRSGVSHPQ
                     LNGVLRAGGGIAVEEAVAQARERLAGVPWMWWVGPDSRPGLAEGLAAAGAAEVATMPVM
                     AVALDRVTMPDGPAGLRIEEVTGADALREWVSAYAPSFGVMPDQVEQVTRVEEWRGDEE
                     GAIVRFAGRLDGRVVGTSVLLDRRGVAGIYVVTTREGYRRRGIGAALTAAALQEGRERG
                     LRVATLQASAMGAPVYRRMGFEVVSAYRMFTLPPAAG"
     gene            complement(7394..7519)
                     /locus_tag="BKM31_RS64085"
     CDS             complement(7394..7519)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS64085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268966935.1"
                     /transl_table=11
                     /translation="MITAERLGLPFTTYRRHLAAGVQRICADLWRRELYGSAGKL"
     gene            complement(7678..9429)
                     /locus_tag="BKM31_RS03120"
                     /old_locus_tag="BKM31_03095"
     CDS             complement(7678..9429)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="BKM31_RS03120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03095"
                     /product="ATP-binding protein"
                     /protein_id="WP_196223968.1"
                     /transl_table=11
                     /translation="MGRRAALGQRLRGVSAAAFVGRRQELDTFDAALRGDRFSVLFVHG
                     PGGIGKSALLRRFAERAADAGRTVIRLDGRVLSPTPEAFEAEAGAVLRDERAVLLVDTF
                     EQIQGLEGWLRERFLPRLPVGALVVLAGRTPPDLCWRAEPGWAGVLEVTRLGELGPEEA
                     RALVEARGLAAGLREPLLSFAGGNPLALSLGAAVAAADEQAGSRWTPSQDVILTLLDQL
                     VGDLPSPAHRRALDVCAHVHMTTEELLRAALPGDDATALFAWLRRLPFVESSAMGLYPH
                     DVVRELLEADLRWRAPDGYARMHRRVHGHLSLKVRTVPDAEVLAAAAALTFPHRGDPLS
                     ARFFTSWRGHGEVQEGPFRDADLDALLQVAGTEGQESADCALFWLRRRSADFRVYRLTR
                     TGEPVAFRAWLRLHAPDKDELATDPIIAAAWAHARATEPLRPGEHIAVSRPWVLPSYRG
                     SSPAMDLIQWRGTGDRVRSQGLAWSYSVRHDPDDCRDFLRQYDFIEVPRRPRVGEIEFG
                     LFAQDWRKMPAQVWLDRLSDLPPLAPHETEAPGQGSLAVLNEEEFHAAVRKALRRLSRP
                     ASWPRAR"
     gene            complement(9432..10007)
                     /locus_tag="BKM31_RS03125"
                     /old_locus_tag="BKM31_03100"
     CDS             complement(9432..10007)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF044515.1"
                     /locus_tag="BKM31_RS03125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03100"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_080036686.1"
                     /transl_table=11
                     /translation="MTTTTPKRADALENRHVILAAALEALTESPDVSLNAIAKRAGIAN
                     GTLYRHFPTREALVLAVYQCDIEEMRDAATRLLAEHAPLDALREWLRSLAACAMTKHGL
                     ADAMRLATGAGKSLFPETYQAMKAAIGELLAAGEAAGVVRPGLDPELVLLALCGIWQLD
                     PGAHWRGQADDLIDLLVTGLAGDAASRG"
     misc_feature    10044..10057
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.87"
                     /tool="antismash"
     gene            10110..11072
                     /locus_tag="BKM31_RS03130"
                     /old_locus_tag="BKM31_03105"
     CDS             10110..11072
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017596568.1"
                     /locus_tag="BKM31_RS03130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03105"
                     /product="aldo/keto reductase"
                     /protein_id="WP_080036687.1"
                     /transl_table=11
                     /translation="MPVLGSSGLPIFPLALGTNTFRWTASAEESHRILDAFVAGGGTFL
                     DTADVYSIWAPGSSGGDAETVIGEWLAAGADRDKVTIATKVSSHPAYPGLKAGNVAAAI
                     EQSLKRLRTDYVDVYYAHADDPGTPLEETVAAFDDLVRRGLVRHVGLSNYDAARVQEWI
                     DIARATGAALPVTLQPHYNLLHRADFERRLRPVAERNDLGVVPYQGLAGGFLTGKYLSA
                     ADAQDAQRGPMLGGYLTEPGFAVARELRAVADELGTSPATVALAWLRAQPTVVAPIASV
                     STAGQLDALLASATLDLSPDQLARLTAASDRYAATRAAA"
     gene            complement(11093..11698)
                     /locus_tag="BKM31_RS03135"
                     /old_locus_tag="BKM31_03110"
     CDS             complement(11093..11698)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017579212.1"
                     /locus_tag="BKM31_RS03135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03110"
                     /product="response regulator transcription factor"
                     /protein_id="WP_080036688.1"
                     /transl_table=11
                     /translation="MIRVLIAEDMHMIRSALVALLSLEDDMEVVAEIERGDEVLATALR
                     TEPDVAVLDIDLPGLDGLSAAEQLSARLPACRTLVLTGLSQPGNLLRALKVHVRGFIVK
                     DAPAHALTDGIRRIARGERVIDPELVAAALETGSSPLTPRETEVLRAAATGIRVAQIAT
                     DLSLSQATVRNYLSNAISKVGARNRIDAIRISRDAGWL"
     gene            complement(11695..12918)
                     /locus_tag="BKM31_RS03140"
                     /old_locus_tag="BKM31_03115"
     CDS             complement(11695..12918)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="BKM31_RS03140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03115"
                     /product="histidine kinase"
                     /protein_id="WP_080036689.1"
                     /transl_table=11
                     /translation="MTPPITPRWVVRHPLWPLIALHVVLAGQVPVYTALGMDGPAGDPL
                     AGTVAFVLALCLSLRHSLAATRGERPAGWPWTLAALVALANVPLWWFGSNWQAFTGFAL
                     ASMVMLLRGRPLWLAAIAQLLHNPVKEVIGMLHDDAYTVAQALLLGSYSLFSLVLYAGT
                     LVGGARLVRLLHELEATRTELAATAVGEERVRVSRDLHDLLGQSLSAISLKGDLALRLL
                     AKDAAAARAEVESLTGVARDALRDVRAITRDEHSVSLRTEIDGAAALLGAAGVDTRLDV
                     ADVPPLSGAAQSALAWAIREGTTNLLRHSDARTCTITLTHRQGTVRLEIVNDGAHPAPA
                     PAPTGAAGPSPAPSGTELSEAAGPSPTPPGTGLAGLAERARAASGTWLTTVRDGLFTLS
                     VEVPEEVA"
     gene            complement(12915..14147)
                     /locus_tag="BKM31_RS03145"
                     /old_locus_tag="BKM31_03120"
     CDS             complement(12915..14147)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS03145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_03120"
                     /product="hypothetical protein"
                     /protein_id="WP_080036690.1"
                     /transl_table=11
                     /translation="MGFWRSDRVVRLAPAGAVACSGLLPLLQVALAFSYPGNDTRTGLW
                     SVAATAAYLPLHLRHVWYAARAARQPAGHWTFAAMAVIVLAATPVAGNMWPRAYTSLAV
                     SAVLVLPGPWAFAAYLALVLAAAPASLLLGLPWNAAPWLTLSTLCGSGAVLMLVWLSAA
                     LVRLRSAREVLAQRAVAQERRRIDDDLRHTLGTALESLAARGTRATSLLTPLLDGQAEL
                     GERTELDRRAALDARAALDRRAELDRRRAELVAELSRLADDSRRTLADARQRVRGYRQP
                     SLRAELDTAAALLSAAGIETRLHLPRTGVPDTIAPQPRAALRATVTRLLRADGVRACTI
                     TAVAQPGGARLEVRTDDTMETIDVRPATDPTKADPTKARTSETSPTDTHPSQTSPTEAG
                     QSQTSPSEARS"
     gene            complement(14260..14739)
                     /locus_tag="BKM31_RS03150"
                     /old_locus_tag="BKM31_03125"
     CDS             complement(14260..14739)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (0-146). E-value:
                     1.5e-09. Score: 30.4. Matches aSDomain:
                     nrpspksdomains_BKM31_RS03150_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019928.4"
                     /locus_tag="BKM31_RS03150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03125"
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_080036691.1"
                     /transl_table=11
                     /translation="MASVQITRTYPTTPEHVWQLWTTPEGIVSWWSPDGFTVEVGKLDL
                     RPGGDLIYTMTATAPEQIAFMESHGMPLNTESRKTFVEVSEPGRLSYTSLADFIPGVDP
                     YDFLTVVELQPVEDGVRVTMTADAMHDEEWTQRLAAGRANELDNLGRVIDAGVRA"
     aSDomain        complement(14302..14739)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS03150_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.50E-09"
                     /label="BKM31_RS03150_Polyketide_cyc2.1"
                     /locus_tag="BKM31_RS03150"
                     /protein_end="146"
                     /protein_start="0"
                     /score="30.4"
                     /tool="antismash"
                     /translation="MASVQITRTYPTTPEHVWQLWTTPEGIVSWWSPDGFTVEVGKLDL
                     RPGGDLIYTMTATAPEQIAFMESHGMPLNTESRKTFVEVSEPGRLSYTSLADFIPGVDP
                     YDFLTVVELQPVEDGVRVTMTADAMHDEEWTQRLAAGRANEL"
     gene            15001..18831
                     /locus_tag="BKM31_RS03155"
                     /old_locus_tag="BKM31_03130"
     CDS             15001..18831
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (33-403). E-value: 4.9e-77.
                     Score: 251.1. Matches aSDomain:
                     nrpspksdomains_BKM31_RS03155_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (505-573). E-value: 1.9e-14. Score:
                     45.6. Matches aSDomain: nrpspksdomains_BKM31_RS03155_PCP.1"
                     /NRPS_PKS="Domain: TIGR02353 (592-1272). E-value: 1.9e-211.
                     Score: 695.8. Matches aSDomain:
                     nrpspksdomains_BKM31_RS03155_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892701.1"
                     /locus_tag="BKM31_RS03155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03130"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_080036692.1"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-62, bitscore:
                     209.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.1e-06, bitscore:
                     26.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 3.8e-209, bitscore:
                     695.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDSVDVSQKAASAVYPAGVLAASPRTLVDVLDETARLHPDAPA
                     LDDGTVCWSYRDLRAEVGRMAAELAEAGIGRGARVGVRVVSGTAELYLSILAVLAAGAA
                     YVPVDADDPDERAELVFTEAAVDAVITDKIKVLGGGRDDGGPPAPDDDAWIIFTSGSTG
                     KPKGVAVTHRSAAAFVDAEAGLFLRERPIGPGDRVLAGLSVAFDASCEEMWLAWRHGAC
                     LVPAPRALVRTGMDLGPWLAGKGITVVSTVPTLAALWPAEHLDGIRLLIFGGEACPPEL
                     AARLAVPGREVWNTYGPTEATVVASAAPLTGEQPVRIGLPLDGWDLAVVGDDGEPVAMG
                     ETGELVIGGAGLARYLDPVKDAEKYAPLPSLGWARAYRSGDLVRADPEGLVFVGRADDQ
                     VKLGGRRIELGEVDAALQALPGVTGAAAAVRTAGGGHQLLVGYVVTGPGFDAGEARDLL
                     ADSLPAALVPRLAPVGALPTRTSGKIDRDALPWPLTGRLAVSELTPAEARLAGHWTAIL
                     GVAPEGPGDDFFASGGTSLAAARLVSVLRPDHPDVAVGDVYAHPTLAGLAALLATRGGS
                     EAARPPVTPMPRRAATVQALLMVPLLTAGAMRWIVPLAALGNVLAAPWAPALSWWWVAL
                     GALAFLTPMGRVGLSAALARLLLRGVRPGSHPRGGGVHLRLWFAEQFAARLGVPDLASA
                     PLMTWYARLLGAQVGEDADLHSPPPVTGLLKVGRGASIEQEVDLSGHWFDGDVLHVGEI
                     RIGAGATIGSRSTLLPGAKIGKNSQVAPGSAVAGAVPSGELWAGVPAFRQGRSRKPGER
                     AARSPWWTALYGVTAVALGLLPVAAAGAAFAVLAWSAREARTLGAALAAALPGVPLATV
                     TGMAAFALLTLASVRLLGLGLHAGQHPVHSRQAWQAWATGRLMASARVWLFPLYASVLT
                     PAWLRALGMKVGRGAELSTVLALPTMTSVGDGAFLADDTMVAPYELDGGWMRIATARIG
                     KRAFLGNSGMTAPGRKVPKDGLVGVLSATPKKAKSGSSYVGMPPMKLRRTAEEGDRNRT
                     YDPPARFKVARAVVEAFRVVPAMAAVALAVLAAAAFEAVAARYGFAAAIALSGVIMAVA
                     GVVAAAVATAAKWLLVGRIGAGSRPLWSSFVWRNELADNFVEVLAAPWFAQPWLGTAPL
                     NVWLRSLGARIGHGVTCDTYWLPEADLVTLGDGACVNRGCVLQTHLFHDRVMSMDTVTL
                     DAGATLGPHGVVLPAARVGADTTVGPASLVMRGEHVPDRTRWFGNPVSAWR"
     aSDomain        15100..16209
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS03155_AMP-binding.1"
                     /evalue="4.90E-77"
                     /label="BKM31_RS03155_AMP-binding.1"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="403"
                     /protein_start="33"
                     /score="251.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DETARLHPDAPALDDGTVCWSYRDLRAEVGRMAAELAEAGIGRGA
                     RVGVRVVSGTAELYLSILAVLAAGAAYVPVDADDPDERAELVFTEAAVDAVITDKIKVL
                     GGGRDDGGPPAPDDDAWIIFTSGSTGKPKGVAVTHRSAAAFVDAEAGLFLRERPIGPGD
                     RVLAGLSVAFDASCEEMWLAWRHGACLVPAPRALVRTGMDLGPWLAGKGITVVSTVPTL
                     AALWPAEHLDGIRLLIFGGEACPPELAARLAVPGREVWNTYGPTEATVVASAAPLTGEQ
                     PVRIGLPLDGWDLAVVGDDGEPVAMGETGELVIGGAGLARYLDPVKDAEKYAPLPSLGW
                     ARAYRSGDLVRADPEGLVFVGRADDQVKLG"
     aSModule        15100..18816
                     /complete
                     /domains="nrpspksdomains_BKM31_RS03155_AMP-binding.1"
                     /domains="nrpspksdomains_BKM31_RS03155_PCP.1"
                     /domains="nrpspksdomains_BKM31_RS03155_TIGR02353.1"
                     /locus_tags="BKM31_RS03155"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       15286..15327
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS03155_0001"
                     /evalue="1.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="109"
                     /protein_start="95"
                     /score="15.1"
                     /tool="antismash"
                     /translation="LAVLAAGAAYVPVD"
     CDS_motif       15457..15516
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS03155_0002"
                     /evalue="1.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="172"
                     /protein_start="152"
                     /score="29.8"
                     /tool="antismash"
                     /translation="AWIIFTSGSTGKPKGVAVTH"
     CDS_motif       15649..15675
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS03155_0003"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="225"
                     /protein_start="216"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="WRHGACLVP"
     CDS_motif       16015..16062
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS03155_0004"
                     /evalue="1.80E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="354"
                     /protein_start="338"
                     /score="17.2"
                     /tool="antismash"
                     /translation="MGETGELVIGGAGLAR"
     misc_feature    16102..16104
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       16174..16236
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS03155_0005"
                     /evalue="8.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="412"
                     /protein_start="391"
                     /score="30.8"
                     /tool="antismash"
                     /translation="FVGRADDQVKLGGRRIELGEV"
     aSDomain        16516..16719
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS03155_PCP.1"
                     /evalue="1.90E-14"
                     /label="BKM31_RS03155_PCP.1"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="573"
                     /protein_start="505"
                     /score="45.6"
                     /tool="antismash"
                     /translation="EARLAGHWTAILGVAPEGPGDDFFASGGTSLAAARLVSVLRPDHP
                     DVAVGDVYAHPTLAGLAALLATR"
     aSDomain        16777..18816
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS03155_TIGR02353.1"
                     /evalue="1.90E-211"
                     /label="BKM31_RS03155_TIGR02353.1"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="1272"
                     /protein_start="592"
                     /score="695.8"
                     /tool="antismash"
                     /translation="VQALLMVPLLTAGAMRWIVPLAALGNVLAAPWAPALSWWWVALGA
                     LAFLTPMGRVGLSAALARLLLRGVRPGSHPRGGGVHLRLWFAEQFAARLGVPDLASAPL
                     MTWYARLLGAQVGEDADLHSPPPVTGLLKVGRGASIEQEVDLSGHWFDGDVLHVGEIRI
                     GAGATIGSRSTLLPGAKIGKNSQVAPGSAVAGAVPSGELWAGVPAFRQGRSRKPGERAA
                     RSPWWTALYGVTAVALGLLPVAAAGAAFAVLAWSAREARTLGAALAAALPGVPLATVTG
                     MAAFALLTLASVRLLGLGLHAGQHPVHSRQAWQAWATGRLMASARVWLFPLYASVLTPA
                     WLRALGMKVGRGAELSTVLALPTMTSVGDGAFLADDTMVAPYELDGGWMRIATARIGKR
                     AFLGNSGMTAPGRKVPKDGLVGVLSATPKKAKSGSSYVGMPPMKLRRTAEEGDRNRTYD
                     PPARFKVARAVVEAFRVVPAMAAVALAVLAAAAFEAVAARYGFAAAIALSGVIMAVAGV
                     VAAAVATAAKWLLVGRIGAGSRPLWSSFVWRNELADNFVEVLAAPWFAQPWLGTAPLNV
                     WLRSLGARIGHGVTCDTYWLPEADLVTLGDGACVNRGCVLQTHLFHDRVMSMDTVTLDA
                     GATLGPHGVVLPAARVGADTTVGPASLVMRGEHVPDRTRWFGNPV"
     CDS_motif       17503..17532
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS03155_0006"
                     /evalue="7.10E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="844"
                     /protein_start="834"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="VAAAGAAFAV"
     CDS_motif       18673..18714
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS03155_0007"
                     /evalue="7.80E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="BKM31_RS03155"
                     /protein_end="1238"
                     /protein_start="1224"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="LDAGATLGPHGVVL"
     gene            18822..20135
                     /locus_tag="BKM31_RS03160"
                     /old_locus_tag="BKM31_03135"
     CDS             18822..20135
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892702.1"
                     /locus_tag="BKM31_RS03160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03135"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_080036693.1"
                     /transl_table=11
                     /translation="MAMTEQIHSTPHLPGDPYFPAHGDHRYGVSHYDLRLTYRVAANRL
                     DGTALLTVTAAQPLSALELDFAQLRVAGVTVDGLPARYAHGRGKLRVTPSRPLAAGERV
                     VVGVRYSGKPVPVPSPWGGLGWEELSDGALVAGQPIGAPSWFPCNDRPGDKASYRISVT
                     TATPYQVIANGALLARRRGAGNTTWIYEQPEPMATYLASVQIGRYQISEYGGARLAHPP
                     RLATRVRHDFARQGQMMALFGDLFGPYPFTGYTVVVADDDLEIPVEAQGMSIFGRNHVD
                     GVRGGERLVAHELAHQWFGNSLTVARWSDIWLQEGFATYAEWLWSESSGGPPAAEHARR
                     WRHRLTQLPQDFVLSDPGAPALFDDRVYKRGALTLHALRGAMGDEPFFTALRAWTAAHR
                     HGTVTTGEFAEHVQRHTDRPVAPLLSAWLHDRSLPDLT"
     gene            20181..20615
                     /locus_tag="BKM31_RS03165"
                     /old_locus_tag="BKM31_03140"
     CDS             20181..20615
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573139.1"
                     /locus_tag="BKM31_RS03165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03140"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_080046460.1"
                     /transl_table=11
                     /translation="MSDETVELSPSDWVRDQTKKILETGTTEGIDIAGSPIVLLTLRGA
                     KSGKLRYTPVMRVEHEGRYAVVASKGGAPEHPTWYYNIKAHPEFTLQDGTVTKRYVARE
                     VEGAERAEWWERAVAAYPAYAEYQTKTDRQIPVFVLDPKE"
     gene            complement(20661..20936)
                     /locus_tag="BKM31_RS03170"
                     /old_locus_tag="BKM31_03145"
     CDS             complement(20661..20936)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015735.4"
                     /locus_tag="BKM31_RS03170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03145"
                     /product="YciI family protein"
                     /protein_id="WP_080036694.1"
                     /transl_table=11
                     /translation="MALFVLTYGYNDTPLRAERRDDHLAHLNKLWERGAVVAAGPYTDL
                     TAGMIVLRAEDEAAAQALVDQDPYTQLDVTKDRTLREWRVTVGSLD"
     gene            complement(20978..21886)
                     /locus_tag="BKM31_RS03175"
                     /old_locus_tag="BKM31_03150"
     CDS             complement(20978..21886)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016777.4"
                     /locus_tag="BKM31_RS03175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03150"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_080046461.1"
                     /transl_table=11
                     /translation="MPEAAPYSGDIVDAHHHIWRVADLPWLSGPMVPRIFGPYEAIRRD
                     YLIDEYAADATACGITESVYVQTNWPLDRVVDEVRWLRDVHEETGRPSAVVAAADLFDD
                     DTPRVLRRQAALTPLVRGIRQQLHWHERPEFRFATAPDRMKDPVLRKNLGAVADLGWLF
                     ELQVFPEQMADAADLVAAFPDLTFVLVHAGMLIGEEYVEPWRAGLSALAELPNVVVKLT
                     GQGTFVHRVDPELISFVAGEVLARFGAGRAMFGTNFPVERLWTTMPHLVGAWKDALAHL
                     PPADRHAVFAGTARRVYGLGG"
     gene            complement(21892..23007)
                     /locus_tag="BKM31_RS03180"
                     /old_locus_tag="BKM31_03155"
     CDS             complement(21892..23007)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017569.4"
                     /locus_tag="BKM31_RS03180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03155"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_080036695.1"
                     /transl_table=11
                     /translation="MTERALVARVREHVHGFLRDLHGQGLRVPVSKQRVFLQAIEAAGP
                     RDATELYWIGASTLTASRADLEVYSPTFERWFGAARARPVPEREFPDEEEPAPRGKGDE
                     APFAAAPGGEAGLEAGFSERVGRPAFGTASRDERAVLALLRRELRGAVPTVRSRRRRPA
                     RRGPWIDVARICRESRRSHGEIVTLRRRNRPRRQRRVLLLIDVSGSMKQHSAAYLRFAH
                     AMVGCLDRVEVFTFGTRLTRVTEPLRARDVDAAVAALSEVVLDAEGGTRIGPSLQEFLG
                     NARHVTMARGALVIVLSDGLERGDPLPMEAAVRRLSLLGHRLLWWTPLACDPAYQPVTR
                     GMAAVLGSVDALAGVRDLRTAYEQVQTLARE"
     gene            complement(23000..23857)
                     /locus_tag="BKM31_RS03185"
                     /old_locus_tag="BKM31_03160"
     CDS             complement(23000..23857)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852529.1"
                     /locus_tag="BKM31_RS03185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03160"
                     /product="MoxR family ATPase"
                     /protein_id="WP_080036696.1"
                     /transl_table=11
                     /translation="MLADQETLGRRLGAEGYLADEGLLTAVRLAGLLGLPLLLEGEPGV
                     GKTEIANVLARVLGRELIRLQCYEGLDASQALYEWDYPKQLLSLRAAEVEGRGVGDLYR
                     EEFLLQRPLLRALRAASGAVLLIDEIDRADSEFEAFLLEFLGDFQITIPEIGTIRAASV
                     PFVILTSNRTRELHDALKRRCLYHWIPFPDAEREQAIIQAQAPGLDERSAARLVAAVHR
                     IRGLALLKRPGIAESTSWARGVQALTREGAGWLEAMRRSAGLLVKYEEDLSLVGRHAAE
                     VFGD"
     gene            complement(23847..24863)
                     /locus_tag="BKM31_RS64780"
                     /old_locus_tag="BKM31_03165"
     CDS             complement(23847..24863)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF042649.2"
                     /locus_tag="BKM31_RS64780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03165"
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="WP_080036697.1"
                     /transl_table=11
                     /translation="MAIRQGRGYAAVNYPTGMNLGGDPSQALVHATTMGGFVVTLSSVD
                     LGQGLRTVVAQCAAETLGVPLENVIVDTADTDTGPHCMGTFASRGTHRVGNAVIMAARE
                     AREVLLRVAADELEVDAEDLETDGTGFVRLKGAPEKKIHVSEVALAAHFRQGRTISGRG
                     IFLKEPSTPVPETGEMDPDSCQAHACTVAEVEVDDETGVIEVLRLYNTYEVGRALNPAI
                     ATQQVEGGAWMGLSHALFESTEPYYPHSREHGPLDFAAYLMPGPADLPEQTSVFLERPA
                     GNGPFGAKGIGEMTANAPIPAIANAVFDAVGVRLTSMPFTPEKVLRGLDELRAGRAG"
     gene            complement(24867..26246)
                     /locus_tag="BKM31_RS64785"
                     /old_locus_tag="BKM31_03170"
     CDS             complement(24867..26246)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014758.4"
                     /locus_tag="BKM31_RS64785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03170"
                     /product="molybdopterin cofactor-binding domain-containing
                     protein"
                     /protein_id="WP_080036698.1"
                     /transl_table=11
                     /translation="MGRLTPIDTTYFKDERAGDFTVIGSAVQRSDARGHVTGRTLFFED
                     LTPPGLTHVKIHRSTRHHARIDRVDVSGALEVPGVLRVITHEDVPNNWYVVLRLIGVGP
                     DDEPVLAEDRVLYRGEPIVAVVAETEEAAREGAARVVVDYTDLPAVLDVEAALADGAPI
                     IKQAGTNHFVYEGHPCRRIRFGDVERGFAEADRIIEGRYSSSPIEHAPVEPTGCIVVPQ
                     GDGRLRIHSNTQAAFFTLDNTALILGVPPTSLRVVGGTVGGGFGGKVDVIVEPLACLAA
                     MLTGRPAKYVYSRAEEMQVSSTRAAEHIHIKDGVMDDGRIVARQVTLYVDAGAYSRHSP
                     YGTTKAAAHMPGPYTIPNVHVDCYCVYTNRTPSSAMRGFGVTIGDFALESHMDHVAREL
                     GMDPLRLRLKNAYRDGDMKAHRKIASGTALVEVIQSAADLVGHDLPPEYRAMSSAERPE
                     G"
     gene            complement(26246..26824)
                     /locus_tag="BKM31_RS03200"
                     /old_locus_tag="BKM31_03175"
     CDS             complement(26246..26824)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017540653.1"
                     /locus_tag="BKM31_RS03200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03175"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_080036699.1"
                     /transl_table=11
                     /translation="MPSTIVTLKLNGTERELIARPSTTLLSALRDTFGLTGAKRGCAQG
                     GCGSCTVLLDGRPAVSCLIPVVTVDGCAVETVEGLADGDRLDDVQQAFVDHFATQCGFC
                     TPGMIMSATALLNREPAPTRQDVTEAICGNVCRCTGYEPIVTAVLSAAESRRDGAAEGR
                     HDSAAERRHDGAGERHRDAAAPLSGKAAG"
     gene            complement(26836..27615)
                     /locus_tag="BKM31_RS03205"
                     /old_locus_tag="BKM31_03180"
     CDS             complement(26836..27615)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013134.4"
                     /locus_tag="BKM31_RS03205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03180"
                     /product="FAD binding domain-containing protein"
                     /protein_id="WP_186404278.1"
                     /transl_table=11
                     /translation="MPDSAEAAHASLQAGAVPLGGGTHLLTRMNDEAGPDLRVVSLRKA
                     GLRGIDVDGDTVTLGAATTLADLEDDPRLGYLAGCVRSIASPPVRTLATVAGNLFVPQP
                     YGDLAAALLALDAELDVLGTAGLRRERLERVVADGLPEGELVTRIRFTAPAPGTFRFHK
                     ASRRRLNSGSIVTVAARLTVEDGLVGDVRLVLGGLSRRLLRAAGAERVLRGAPLTAEVV
                     AEAAGADVIEPFDDAYASAWYRARVYPVHLRRALLGA"
     misc_feature    27644..27658
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    complement(27647..27661)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            27721..28503
                     /locus_tag="BKM31_RS03210"
                     /old_locus_tag="BKM31_03185"
     CDS             27721..28503
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.4"
                     /locus_tag="BKM31_RS03210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03185"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_155126445.1"
                     /transl_table=11
                     /translation="MPEPTGNLGPAQPGAQPGAQPGAQPGAQPAPPPAPQSAGPRSARP
                     TLSRQIRDGLLRRIVSGELGEGDRLIETKIAQEFGTSQAPVREALRQLEGLGLIESQPR
                     HGSRVLPFVEQTIREAYILRAALEETATRLAMLAGTLPFDLLQEAVEEMRRCARDGDVP
                     GIGLASARFHRHVVQAGGNALLTRAWEALQIEARTAIALMVTGPELERVAEEHHELLDV
                     MRAGDVETACRHARDHQWAYADTPHDPYGTPRGGHRDT"
     gene            complement(28528..29568)
                     /locus_tag="BKM31_RS03215"
                     /old_locus_tag="BKM31_03190"
     CDS             complement(28528..29568)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012371.4"
                     /locus_tag="BKM31_RS03215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03190"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_186404277.1"
                     /transl_table=11
                     /translation="MTDAPLDDLVRRTAEELAARRRGAVAVGAIRGEERATHGAGPHTV
                     FEIGSITKTFTALTLARLAGRGEVAFEQPVRELLPDGAAVPRRDGREIELVHLACHTSG
                     LPRLPKGLMPGALFSLDPYAGCTEEVLLAGLARTRLRSVPGSRFRYSNLGGGLLGLALA
                     RQTGLGYDELVQREICRPLGLADTRVVLDGERAARLAPGHSRSGRPRPGWRLAALAGAG
                     GLHSTAHDLLRLAAATFGSGPAEIAEAVARTRAVGHPISGVSTAHAGWLSVERARDKGG
                     PRVLFHNGGTGGYRSLLAVIPERRTAVVVLSADARSVDGAGMRLLSDLTDRDGTDEPPP
                     HEPGTP"
     misc_feature    complement(29651..29664)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.34"
                     /tool="antismash"
     gene            complement(29671..30420)
                     /locus_tag="BKM31_RS03220"
                     /old_locus_tag="BKM31_03195"
     CDS             complement(29671..30420)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009084228.1"
                     /locus_tag="BKM31_RS03220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03195"
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="WP_080036703.1"
                     /transl_table=11
                     /translation="MLAAQRRELLLERLARDGKIIAKDLAAELGLSEDSIRRDLRDLAA
                     AGLCQRVYGGALPASPAIADYATRQGVEVSGKQRVAAAAAALVRPGSTAIIDGGTTALA
                     VARALPPDLRATVVTHSPTVAGALAEHHDVEVYLIGGRLFKHSMVSCGAAAVEAARGVN
                     ADLFLLGVTGVHPETGLTTDDADEAAMKRTLARQAADTYVLASSEKIGAASRFSVLPLT
                     EVAAVITDADAGNATVRALGIPVIHAP"
     misc_feature    30375..30389
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.54"
                     /tool="antismash"
     misc_feature    complement(30447..30460)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.92"
                     /tool="antismash"
     misc_feature    30470..30483
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.81"
                     /tool="antismash"
     misc_feature    complement(30470..30485)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            30471..30827
                     /locus_tag="BKM31_RS03225"
                     /old_locus_tag="BKM31_03200"
     CDS             30471..30827
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS03225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_03200"
                     /product="hypothetical protein"
                     /protein_id="WP_222107497.1"
                     /transl_table=11
                     /translation="MMILIAGPYRSGTGDDPELMARNLARLEEAAWPVFRSGHVPMIGE
                     WVALPVLRGAGGGGPADPVAEEIMYPTAERLLRHCDAVLRLPGESAGADQDVRIATERG
                     LPVYYRVEDIPGYL"
     gene            complement(30834..31736)
                     /locus_tag="BKM31_RS03230"
                     /old_locus_tag="BKM31_03205"
     CDS             complement(30834..31736)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012415.4"
                     /locus_tag="BKM31_RS03230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03205"
                     /product="CAP domain-containing protein"
                     /protein_id="WP_080036704.1"
                     /transl_table=11
                     /translation="MRKPLGVLAAVLGLAACAPSTGSTQGAPSAAVTPQADAPTTPATT
                     PTPKPAPESDKCRVTVARPDVTALTIETSAVRRDCVRPALLRIRIKRAVPGEDPVVKSG
                     AARKDRITLKTPCKPGTYYAVATDYSTDTATSKAVRLTCATPTPTPTVTPTATPTPAPR
                     KTAAQATSAGTALESEVVRLTNAERAKGGCDPLRPDARLRRAAFGHSADMAKRGYFDHD
                     SQDGRDMVDRIRATGFSGSAWAENIAKGQRTAAQVVRDWMNSAGHRENIMNCSYTHIGV
                     GAAKDSSGQTYWTQDFATR"
     gene            31956..33509
                     /locus_tag="BKM31_RS03235"
                     /old_locus_tag="BKM31_03210"
     CDS             31956..33509
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="BKM31_RS03235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_03210"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_080036705.1"
                     /sec_met_domain="Pkinase (E-value: 1.5e-40, bitscore:
                     138.7, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQAQPLREDDPPAVGPYRLLGRLGAGGQGVVYLGQRPDTALVAI
                     KVLRDGRGDGRLAKEVEAARRVEPFCIAQVLDASLSGPRPYIVTEYVDGPSLQQAGRHT
                     GADLQRLAVATATALAAIHQAGIVHRDFKPANVLLGPGGPRVIDFGIARSADSGPSGAS
                     GVMGTPAYMAPEQLAGAPIGPAADVFAWGSVMAFAANGAPPFGEDTLPAVINRILHNEP
                     QLGDLPEPLRTVVLHCLAKDPARRPSMRDVLLRLLGGAQQQPAAVGSPAPPHPGAVGAP
                     QMMAGRGGGASWPGDAGPPTAPRHGAGRMWLVAGVASAVTLVVVSGVAWGVTNVWGERP
                     PSSSPQALPATTTEEPGPTAERKRPKRTRTPHPTRTPSPTRTPSPTPSRKSKEPTVAPT
                     TRTARPTRTAAEGGGTLRIVSLRAQGARTANTQDCQVGQSNIFAVVEGTKLRTQFDYQW
                     ILDGKVVGRSTSYIAESHTQQVIGPLVEPVGSHRVTLRLTSPSTVSRTLTFRICPTGTE
                     "
ORIGIN
        1 tgcccacctc cgccaggcgt cgcacgactc accgtcagat gacggatgtg cgcgatcagg
       61 ggcgcggccg acagtgggag cgcccccatg ggggacggcg gaccgccgcc ttcccgtcca
      121 cattggagat cctgtgcgca ttttcgacgt cgtcgtcatc ggcgccggac cggtcggcga
      181 gaacgtcgcc gaccggacgg ccgccgccgg gctggacacc gtcatcgtgg aagccgagct
      241 ggtcggcgga gagtgctcct attgggcgtg cgagcccagc aaggcgctgc tccggccggt
      301 cctgctgcac gcggaggccc gcgacatgcc cggcatcgac cctggcccgc tggacgtcga
      361 agccgtcctg cggcaccgcg accggatgtc cagcggctgg gacgaccgac cgcaggtgcg
      421 gtggctggag caggcgggca tcaccctgat ccgcgggcat gcgcggctgt ccgggccgcg
      481 gatggtggag gtgaccggtg cggacggcga gaccctgcgg ctggcggccc ggcacgccgt
      541 ggccgtctgc accggaagcc gccccgccct gcccccgctg cccggtctag ccgccctgcg
      601 gccctggacc agccgcgaag ccaccagcgc gacccgggtc ccgccccggc tggccgtcgt
      661 cggcgggggc gtcgtcgccg tcgagatggc caccgcctgg caggccctcg gctcccaggt
      721 caccctcctc gtccgggagt cggggctgct tccccggatg gaacgcttcg ccgccgacct
      781 cgtcgccgac gcgctccgcg cctcgggcgt cgacctgcgc ctcgacacga ccctcaccgc
      841 cgcgacccgc gacaccgacg tccggctcac cctgtcggac gggcaggtgc tgcatgccga
      901 cgagctcctg ctcgcgaccg gccgggctcc ccgcaccgac gacctcggcc tggagaccgt
      961 cggcctgcgc cccggcagcc ggctgccctg cgacgacacc tacaccgtgc ccggcgtccc
     1021 cggcgactgg ctgtacgccg tcggcgacgt caacgagcgc gccctcctca cccaccaggg
     1081 caagtatcag gcgaggatcg ccggtacggt catcgccgac cgggcccgcg accagcccct
     1141 cgaccgcggc ccgtggagcc gccacaccgg aacggccgac caggtcgccg tcccccaggt
     1201 cctcttcgcc gaccccgaga tcgcctgcgt cggcctcacc accgccgacg ccgcgcggct
     1261 gggcagggag gcggacgtcg tcgactacga cctcggcctc gtcgccggcg cccaccagca
     1321 cagccccgct taccggggcc gggcccgcat cctcctcgat cccgcccgcg gcaccctcct
     1381 gggcgccacc ttcgccggcc gcggcgtcgc cgagctgctg cagtccgcga cgttcgccat
     1441 caccggcgag atcccgctgg agcgcctctg gcacgccgtc ccggccttcc cgacgctcag
     1501 cgaggtctgg ctccgcctcc tcgaaaccca tcgggacacc gccgtcccgc tgcgcagcgg
     1561 gcgctgagaa cgggagcacg aacatggagt ggttcttcct gccgtggacc ttcatggcct
     1621 acctgaccgc aggcttcgac ccggccgccc cgccccggac cgaacggcac gggtacgagc
     1681 ctcccggacc cgcggagaag tggatgatcg agaccgccta tgagacggtc gcggccgaga
     1741 accgctgcac acgatgcggc gcccccctgg gccgtccccg tctccgggcg gacgcctggc
     1801 ccgtccgggt cgccgcccgc tgccgcggca ccgcccgcca ccgccaccgc gccgccgtct
     1861 tccgcacccc ggacggcctc cacacccacc ctctcgtccg cgcctaggcg agtccgccgc
     1921 cacccgtctc ggggctgccg tgaatgaccg tcaaatgacg gatgtgacgg acgctcccgc
     1981 ggtcgagagt ggtcacgtca ggaggaccgc cgggatccgc gtacgaggcc acccggcacg
     2041 cggtcgccgg cccgatcaag accgcgggcc ccgaaaaccc cgcaccgggc gcgccgcccg
     2101 ccggaacact cacgcagaaa gcgagaagca catggacatg aagctcgaag tcgtcgtcct
     2161 gcccgtctcc gacgtcgacc gcgccaagga cttctacacc cggcagctcg gcttccgcct
     2221 cgacgccgac ttcccgatca acgacggcta ccggatcgtg caggtcaccc cgcccggctc
     2281 ggcgtgctcg atcatcttcg gcgacggtgt ctccgactcc gcgcccggct cggccgaggg
     2341 gctgcacctg atcgtggcgg acatcgagca ggccgtgaag gagctggtcg gccggggcgt
     2401 cgaggtcacc gagccgttcc acgacgccac cggcgccttc caccacgccg gcgggcgcga
     2461 gcgggtctcc ggcgcgcacc cgcagcgggc cagttacggg tccttcgccg cgttcgccga
     2521 ccctgacggc aacggctgga tcctccagga gatcacggta cgggcgccgg gccgctgact
     2581 cacaccggct caccaccctg acagggcgac ttgcgaaaac ggaggagaac atgatgaaca
     2641 agggaacgct gctgctcgtg cacggcgcct ggcacagtcc gtcgtgctgg gatcggctcg
     2701 tgcccgagct ggaggaacgc ggctggcgca cgtccacggt ggacctgccg agcacgtggg
     2761 gggatccgca ggtggggatg tacgacgacg cgcgggccgt acgggaacgg ctgcttgccc
     2821 tggaggggcc ggtcaccgtg ctcgcgcact cctacggcgg ggtccccgtc agcgaggtgg
     2881 ccgagaccgt gccgaacgtg cggcggctcg tctacctcgc ggcccacatg ctggaggcag
     2941 gggaggcggt gatcacgccg ctcggcgggc cgtggttccc ggaggacgcc gagctgctgc
     3001 cggctcccga ccagccgatc gagacgctct accacgacgt gcccgccgcg tgggcgcagg
     3061 cggccgtcgc ccggctcagg ccgcagagcg cgcgggcgtt caccgagcgg cagacgcggg
     3121 cctcgtggcg ggcgctaccg tccgcgctca tcgtctgcga cgatgaccgg atcatgcccg
     3181 agctgttcat caagcggcag ctcacgatga ccgaggtggt caggcacctg ccgggggacc
     3241 attctccgtt cctgtcgcgg ccgggcgagc tggccggcct cgtcgacgag gtgacggcgg
     3301 ctctgcccgc ccgcggatga ggcagcccgg cgggtgccgc tgagccagag agaggtgaac
     3361 ggtgcagcac ggcgaaccgg ccgccggcac ggtggtcgat ctcgaccggt ccttcttcca
     3421 ggacccccat ccggtctacc ggcgcgtgcg cgaggcgggg ccggtgctgc ccgcgctcgc
     3481 gcaccggcgg ctcagggtct ggctggtcac caggtacgcc gaggccaggg agctgctcaa
     3541 cgatccccgg ctggccaagg acagcgccgg ggcgatggag ctgttcccgc cggggaccgc
     3601 gggcccgtac gcctcgtcgt tgtcggccca catgctcaac tccgacccgc ccgaccacac
     3661 gcgcctgcgc cggctcgtca ccaaggcgtt caccgcgaag acggtgtcgc ggctgcgccc
     3721 gcgcatcgag cagatcaccg acgggctgct cgacggcatg gcggaggcgg gcgagctcga
     3781 cctgatagag gcgttcgcct tcccgctgcc gatcgccgtc atctgcgagc tgctcggcat
     3841 cccggccgcc gaccacgacg tgttcaggac ctggaccgcc ccgttcgtgg cggcctcgtc
     3901 ggcggaggag atgcgggagg cgcacgcgtg gatgctggcc tacctgaccg atctcgtcgc
     3961 cgccaagcgg gccgtgcccg gcgaggacct gctgtcggag ctggtgcaca tctccgacga
     4021 gggcgaccgg ctgtcacggg acgaagtggt gtccatggcg ttcctgctcc tcgtggcggg
     4081 ccacgagacg acggtcaacc tgatcgccaa cagcgtgctc gccctgatcg gcgcgcccgc
     4141 ccagctggcc gcgctgcggg ccgaccccgc tctgctgccg ggcgcggtgg aggagttcct
     4201 gcgcttcgac gggccgatca acatcgcgac cctgcgcttc acgaccgagc cggtgcgggt
     4261 gggcgacgtc gagatccccg cggacgagtt cgtcttcatc tccctgctgg ccgccaatcg
     4321 cgacccggcc cgcttccccg accccgaccg gctcgacgtc acccggccgg gcggcggcca
     4381 cctggcgttc gggcatggca tccactactg cgtgggcgcg ccgctggcca ggctcgaagc
     4441 gcagatcgcc atcggcaggc tgctcgcccg cttctccggc atcgagctgg ccgcgcccgt
     4501 cctgcagtgg cgggccagca ccctcatccg cgggccgcac accctgcccg tccgggtccg
     4561 ctgaacacgg ctgccggcac ccgtgggagg acgcggcccg cgcccggcta cgggcgtccg
     4621 tcggaggccg ccgccgcgcg catgacggcg tcgatcagga ggcggttctc cggggcgccg
     4681 cccccgccgg cggtgaagcg ccggcgggtg tagctgtagg cgatgccgct gcccgggtcg
     4741 gcgaacgact gggcgcccac ggcgccgctg tggccgaagg cgtcggcgcc caggcccggg
     4801 taacgcgcgc ccagggcctc gaagccgagc aggaagtgat cgcgttcccc ggtcaccagg
     4861 tccacgcccg gcgtgtgcgg ccgggtgaac gcggtcagcg tcgccggctc cagcagcgcc
     4921 ggccgcccgt cgaccgggcc gatggcggcg gcgtacagct tggccagccc gcgggcgttg
     4981 cccacgctcc cggacgaggc cgggcccagg gcgcgtacgt gccggtcgtt ggcgaactcc
     5041 accagatcgg tcggccgggc cgcgttgagg ttgaaggcga tgccgagcag gctgtccggc
     5101 gcgggcgggc cggccgcgcc ccgctgctcc ggcgcgagcg gctgaacggg gaggtagcgg
     5161 ggctcctcgt cctcgggcag gccgaggaag aagtccagcc ggtacgggac gcgcacccgt
     5221 tcgtcgtaca cctcctggag cgaacgcccg gtggcgcggc ggaccacctc acccgtcagg
     5281 gccccgatga cgaaggcgtg gtagccgtag ccgctgcccg gccgccagta cggcgcctgc
     5341 ccggccaggc gccgggcgag cagccggtcg tcggccagct ccgccgtgct gaacccgcct
     5401 ggtacgccga tcaggcccgc gcggtgggcc agcaggtcgc gcagggtgat ctcgcccttg
     5461 cccgcggcgg cgaactccgg ccagtagtgg gcgacgcgcc ggtcgagctc cagcgtgccg
     5521 tcctgcacca gcagcgccac gaccaggtgg gccgcgccct tgcccgagga gtacagggcc
     5581 agcagcgagt cgccggtcac ctccgggccg gtccacaggt ccacgaccgg gcggccgtgg
     5641 tgccggacgg cgagctgcgc gccgaggccg ggctcgccgg cggcgatgtc cgcgaacgcc
     5701 cgccggacgt cctcgaaccc cgcggcgacc gtgccgtgga cgatctcgtg gctggtcatc
     5761 aagccggttt ccctcatcat ctccggtcct ttctctcgct gagcggcctg aactgtacag
     5821 cacagttcac atgaactcaa cagtacagtt cagctaggat ggggacgtga cgacaacgag
     5881 caggcgcgtc ccgacgggag agcgcgcggc acgcaagcgg gccgccatcg tgcgggcggc
     5941 ccgccgccag ttcctggagc acggcttcgg cgccggcatg gaccacatcg ccgccgaggc
     6001 cggcgtgtcg aaggtgaccg tctacaacca cttcgccggc aaggaggagc tgttcaccga
     6061 agtggtgagc gacgcgctcg aacaggcgct gggccagacc atgcgcgcca tgaacgagcg
     6121 cctgcgcacc ggcgacgacc tgcgcgacgt cctgtgcgcc accgcccgcg agtgggtcga
     6181 gggcatcgcc cagcccgacg tgctcgcgct gcgcgcgctc atcaccgccg aggcgcggcg
     6241 cttccccgag ctgggccgcc tgtggcgccg gcacggcccc gaccgcttcg ccgagccgct
     6301 ggccaccgcg ctggccgcgc gcgacgacct cgacatcccc cggatggagc tggcgatcgt
     6361 ccagttctac gcgctggtgc tctacccgca catcgtgcac agcgcctacg gcgaccggct
     6421 cgaccccggg ttcaccgacg agctcatcac caccggggtc gacatgttcc tgaagtacta
     6481 ccgcaaacgt tgaccggaag gatcgccact ggacaggaaa ccggactggt gagtggacag
     6541 ttcgtccccc gagactgtca cggacatcat ccgttcgagg gggatctcct gtgacgatca
     6601 ttgacgcggt cgccgagctg gaagggcagc tggccaacac gcgggactac tggctgggat
     6661 ggggcagcgc cgaccggtgc gacggcgagc tgaccctcta ccgcagcggg gtgtcgcatc
     6721 cgcagctgaa cggggtgctc cgggccgggg gcgggatcgc cgtggaggag gccgtcgcgc
     6781 aggcgcggga gcggctcgcg ggggtgccgt ggatgtggtg ggtcgggccg gacagccggc
     6841 cgggcctcgc ggaggggttg gccgccgccg gtgccgccga ggtcgccacg atgcccgtga
     6901 tggccgtggc cctggaccgg gtgaccatgc cggacgggcc ggccgggctg cggatcgagg
     6961 aggtgacggg ggcggacgcg ctgcgggagt gggtgagcgc ctacgcgccc tcgttcggtg
     7021 tcatgcctga ccaggtggag caggtcacgc gggtcgagga gtggcggggg gacgaggaag
     7081 gggccatcgt gcggttcgcc gggcggctgg acgggcgggt cgtcggcacg tccgtgctgc
     7141 tcgaccggcg gggagtcgcc gggatctacg tggtcacgac ccgcgagggg taccggcggc
     7201 gcggtatcgg cgccgccctg acggccgccg ccctccagga gggtcgcgaa cgggggcttc
     7261 gtgtcgccac cctccaggcg agcgccatgg gggcgccggt gtaccggcgg atgggcttcg
     7321 aggtcgtgtc ggcgtaccgg atgttcacgt tgcctccggc cgccgggtaa tccgcgggga
     7381 ggtgtcccgc ccttcagagc ttgccggcgc tgccgtagag ctcccgccgc cacaggtccg
     7441 cgcagatgcg ctggacgccg gcggccagat ggcggcggta ggtggtgaag ggcaggccga
     7501 gccgttcggc ggtgatcaac tggctggggg agccgcgcag gaacgtcgcc tcgacggccc
     7561 ggtgcggctt gcgggcgcgc ggatcgtcgc cgagccgggc gacggcttcg accagcaggg
     7621 cgcgcagtga cgcggcgggg tcgggcccgg ggtcctcggt gaccaggcgg gtgcgggtca
     7681 gcgggctcgc ggccagctcg cggggcggga cagccggcgc agcgccttgc ggacggcggc
     7741 gtggaactcc tcctcgttca ggaccgccag cgaaccctga cccggagcct ccgtctcgtg
     7801 cggcgcgagt ggaggcaggt cgctcagccg gtccagccac acctgggccg gcatcttgcg
     7861 ccagtcctgg gcgaacagac cgaactcgat ctcgcccacc cgggggcgtc gcggcacttc
     7921 gatgaagtcg tactggcgga ggaagtcgcg gcagtcgtcg gggtcgtgcc ggacgctgta
     7981 ggaccaggcc agtccctgcg agcggacccg gtcgccggtg ccgcgccact ggatgaggtc
     8041 catcgccggc gagctgccgc ggtaggacgg cagcacccat ggcctggaca cggcgatgtg
     8101 ctcgccgggc cgcaagggct cggtggcgcg cgcgtgggcc caggcggcgg cgatgatcgg
     8161 atcggtggcc agctcgtcct tgtcgggcgc gtgcagccgc agccaggcgc ggaaggccac
     8221 cggctcgccc gtgcgggtca ggcggtagac gcggaagtcc gccgaccggc gccgcagcca
     8281 gaacagggcg cagtccgccg actcctggcc ctcggtgccg gccacctgga gcagggcatc
     8341 gaggtcggcg tctcggaagg ggccctcctg gacctcgccg tgaccgcgcc agctggtgaa
     8401 gaacctggcc gacagcgggt cgccgcggtg cgggaaggtc agcgcggccg ccgcggccag
     8461 gacctccgcg tcgggcacgg tgcggacctt gagcgagaga tggccgtgga cgcgccggtg
     8521 catccgggcg tagccgtcgg gggcgcgcca gcgcaggtcg gcctccagca gctcccgtac
     8581 gacgtcatgg ggatacaggc ccatcgcgct ggactcgacg aacggcagcc gccgcagcca
     8641 ggcgaacagc gcggtcgcgt cgtcgccggg cagcgccgcg cgcagcagct cctccgtcgt
     8701 catgtggacg tgcgcgcaca cgtccagggc gcgccggtgc gcgggcgacg gcaggtcgcc
     8761 gacgagctgg tccagcagcg tgaggatcac gtcctggctg ggcgtccacc ggctgccggc
     8821 ctgctcgtcg gcggcggcca cggcggcgcc cagcgacagc gccagagggt taccgcccgc
     8881 gaaggacagc agcggctccc gcaggccggc ggccaggccc cgggcctcca ccagcgcccg
     8941 ggcctcctcc gggccgagct cgccgagccg cgtgacctcc aggacgccgg cccagccggg
     9001 ctcggcgcgc cagcacaggt ccggtggcgt ccttccggcc aggacgacca gcgcccccac
     9061 cggcagccgg ggcaggaacc gctcgcgcag ccagccctcc aggccctgga tctgctcgaa
     9121 ggtgtcgacc agcagcaccg cgcgctcgtc gcgcagcacc gcgccggcct cggcctcgaa
     9181 cgcctccggg gtggggctca ggacgcggcc gtccagccgg atcaccgtcc ggcccgcgtc
     9241 ggccgcccgc tcggcgaagc gccgcagcag cgccgacttg ccgatgccgc cgggcccgtg
     9301 cacgaacagc acgctgaacc ggtcgccgcg cagcgccgcg tcgaaggtgt ccagctcctg
     9361 ccgccgcccg acgaacgcgg ccgcggagac gccgcgaaga cgctgcccga gcgcggcccg
     9421 ccggcccaac gctaacccct ggaggccgcg tcgccggcga ggccggtgac gaggaggtcg
     9481 atgaggtcgt cggcctgccc gcgccagtgc gcgccggggt cgagctgcca gatgccgcac
     9541 agcgccagca ggaccagctc ggggtccagg ccgggacgga ccaccccggc cgcctcgccg
     9601 gcggcgagca gctcgccgat cgcggccttc atcgcctggt acgtctccgg gaacagcgac
     9661 ttccctgcgc cggtcgccag ccgcatggcg tcggccagcc cgtgcttggt catcgcgcag
     9721 gcggcgagcg agcgcagcca ctcccgcagc gcgtcgagcg gggcgtgctc ggccagcagc
     9781 cgggtcgccg catcccgcat ctcctcgatg tcgcactggt agaccgccag caccagggcc
     9841 tccctggtgg ggaagtgccg gtacagggtt ccgttcgcga tgccggctcg cttggcgatg
     9901 gcgttcagcg agacgtcggg cgactcggtg agggcctcca gggccgccgc caggatcacg
     9961 tggcgattct cgagcgcgtc ggcgcgcttc ggtgtggtgg tcgtcacgtc tgcctcccgg
    10021 agtttgctaa acggggaact cccattttat ggtgaagcct cccggttccg gggaattccc
    10081 cggaacgttc atcctacaag gagcgcagca tgcccgttct gggatcatca ggtctgccca
    10141 tcttccccct ggccctgggc accaacacct tccgctggac ggcgagcgcc gaagagtcgc
    10201 accgcatcct ggacgcgttc gtggcgggtg gcggcacctt cctcgacacc gccgacgtgt
    10261 actccatctg ggcgcccggc agcagcggcg gcgacgcgga gacggtgatc ggcgagtggc
    10321 tggccgccgg agccgaccgc gacaaggtca ccatcgccac gaaggtctcc agccaccccg
    10381 cctaccccgg gctgaaggcc ggcaacgtcg ccgcggcgat cgagcagtcg ctcaagcgcc
    10441 tgcggaccga ctacgtggac gtctactacg cccacgccga cgaccccggc acgccgctgg
    10501 aggagaccgt cgcggccttc gacgacctgg tacggcgcgg cctcgtccgc cacgtggggc
    10561 tgtcgaacta cgacgccgcg cgcgtccagg aatggatcga catcgcccgc gccaccgggg
    10621 cggccctgcc ggtcaccctg caaccgcact acaacctgct gcaccgcgcc gacttcgaac
    10681 ggcggctgcg gcccgtggcc gagcgcaacg acctcggcgt cgtgccctac caggggctgg
    10741 ccggcgggtt cctgaccggg aagtacctct cggcggccga cgcccaggac gcccagcgcg
    10801 gccccatgct cggcggctac ctcaccgagc ccggcttcgc cgtcgccagg gagctgcgcg
    10861 ccgtggcgga cgagctcggc acgtcccccg ccaccgtggc actcgcctgg ctgcgcgccc
    10921 agcccaccgt cgtcgccccc atcgccagcg tcagcaccgc cggacagctc gacgcgctgc
    10981 tcgcctcggc gaccctcgac ctgtcgcccg accagctcgc caggctcacc gccgcctccg
    11041 accgctacgc ggccacccgg gccgccgcct gaaagggcac gctgggggac ggtcagagcc
    11101 agccggcgtc gcgggagatg cggatggcgt cgatgcggtt gcgggcgccg accttgctga
    11161 tcgcgttcga caggtagttg cggaccgtcg cctgcgacag cgacaggtcg gtggcgatct
    11221 gggcgacccg gatgccggtg gcggcggcac gcaggacctc ggtctcgcgc ggggtgagcg
    11281 ggctgcttcc cgtctccagg gcggcggcga ccagctccgg gtcgatgacg cgttcgccgc
    11341 gggcgatgcg gcggatgccg tcggtgaggg cgtgggcggg ggcgtccttg acgatgaagc
    11401 ccctgacatg gaccttcagg gcgcgcagga ggttgccggg ctggctcagg ccggtcagga
    11461 cgagcgtgcg gcaggccggg agccgggccg agagctgctc ggcggcggac aggccgtcca
    11521 ggcccggcag gtcgatgtcg aggaccgcca cgtcgggctc ggtgcgcagg gcagtggcca
    11581 ggacctcgtc gccacgctcg atctcggcca ccacctccat gtcgtcctcc agcgacagca
    11641 gggcgaccag ggctgagcgg atcatgtgca tgtcctcggc gatcagcaca cggatcacgc
    11701 gacctcctcg gggacttcta ccgacagcgt gaacaggccg tcgcggacgg tggtgagcca
    11761 cgtgccggac gcggcccggg cccgctccgc cagcccggcc agccctgtgc cgggtggggt
    11821 ggggctcggg ccggccgcct cggacagctc cgtgccggat ggggcggggc ttgggccggc
    11881 cgctccggtg ggtgcgggtg ccggggcggg gtgggcgccg tcgttgacga tctccaggcg
    11941 gaccgtgccc tggcggtggg tgagggtgat ggtgcaggtg cgggcgtcgc tgtggcgcag
    12001 caggttcgtg gtgccctcgc ggatcgccca ggccagggcg ctctgggccg ccccggacag
    12061 cggcgggacg tcggccacgt cgaggcgggt gtcgacgccg gcggcgccga gcagggccgc
    12121 ggccccgtcg atctcggtgc gcaacgacac cgagtgctcg tcgcgggtga tcgcgcgtac
    12181 gtcccgcagc gcgtccctcg cgacgcccgt caggctctcg acctcggcgc gggccgcggc
    12241 ggcgtccttc gcgagcaggc gcagagccag gtcgcccttg agggagatgg ccgacaggct
    12301 ctggcccagc aggtcgtgca gatcgcgcga gacgcggacg cgttcctcgc cgacggccgt
    12361 ggcggccagc tccgtgcggg tggcctccag ctcgtgcagc agccgcacca ggcgggcgcc
    12421 gccgaccagc gtgccggcgt acaggacgag actgaacagg ctgtacgagc ccaggagcag
    12481 ggcctgggcg acggtgtagg cgtcgtcgtg cagcatgccg atcacctcct tcaccgggtt
    12541 gtgcaggagc tgcgcgatcg ccgcgagcca cagcgggcgg ccgcggagca gcatcaccat
    12601 cgacgcgagc gcgaagccgg tgaaagcctg ccagttcgag ccgaaccacc acagcgggac
    12661 gttcgcgagg gcgacgaggg ccgccagggt ccacggccag cccgccgggc gctcgcccct
    12721 ggtggcggcc aggctgtggc gcaggctcag gcagagggcc aggacgaagg cgacggtgcc
    12781 ggccagcggg tcgccggccg ggccgtccat gccgagggcc gtgtagaccg ggacctgccc
    12841 ggccagcacg acgtgcaggg cgatcagcgg ccacaggggg tggcgcacga cccagcgcgg
    12901 cgtgatcggc ggcgtcatga ccgggcctcc gacgggcttg tctgcgactg gccggcctcg
    12961 gtcgggctcg tctgcgatgg gtgggtgtcg gtcgggctcg tttccgacgt gcgagccttc
    13021 gtcgggtcgg ccttcgtcgg gtcggtggcg ggccggacgt cgatggtctc catggtgtcg
    13081 tcggtgcgca cctccaggcg tgccccgccc ggctgggcga ccgccgtgat cgtgcaggcg
    13141 cgcaccccgt cggcgcgcag caggcgggtg accgtcgcgc gcagggccgc acggggctgc
    13201 ggcgcgatcg tgtcggggac gcccgtgcgg ggaaggtgca ggcgggtctc gatgccggcg
    13261 gcggagagca gggcggcggc cgtgtcgagc tcggcgcgca gggacggctg ccggtagccg
    13321 cgcacccgct gccgggcgtc ggcgagcgtg cgccgcgaat cgtcggcgag cctggacagc
    13381 tccgccacca gctcggcccg ccgccggtcg agctccgccc gccggtcgag cgcggctcgc
    13441 gcgtcgagcg cggcgcgcct gtccagctcg gtccgctcgc cgagttcggc ctgcccgtcg
    13501 agcagcggcg tcaggaggct ggtggcgcgg gtgccgcggg cggcgaggga ttcgagggcg
    13561 gtgccgaggg tgtggcggag gtcgtcgtcg atgcggcgtc gttcctgcgc caccgcccgc
    13621 tgggcgagca cctccctggc cgaccgcagg cggacgaggg cggcggacag ccacacgagc
    13681 atgaggacgg ccccgctgcc gcacagcgtc gagagcgtga gccatggggc cgcgttccac
    13741 ggcaggccca gcagcaggga cgcgggcgcc gccgcgagca ccagcgccag gtacgccgcg
    13801 aacgcccacg ggccgggcag gaccaggacc gccgacacgg cgaggctcgt gtaggcgcgc
    13861 ggccacatgt tcccggccac gggggtggcg gcgaggacga tcacggccat ggccgcgaag
    13921 gtccagtggc cggccggttg ccgggcggcg cgggcggcgt accagacgtg gcgcaggtgg
    13981 aggggcaggt acgcggcggt cgccgcgacg ctccacagcc cggtgcgggt gtcgttgccg
    14041 gggtagctga aggcgagcgc gacctgcagc aggggcagca ggccgctgca ggcgaccgcg
    14101 ccggccggtg cgagccggac gacgcggtcg gaccgccaga accccaccag ccgaaccgcc
    14161 cctcgtccac gtgccctggc tgaccagggt aggtgacccg gccgatcggc gaccaccagc
    14221 ggcggccggg acggggagag ggggagggtc atgcccggct caggcccgca cgcccgcgtc
    14281 gatcacccgg ccgaggttgt cgagctcgtt ggcccggccg gcggccagcc gctgtgtcca
    14341 ctcctcgtcg tgcatcgcgt cggccgtcat cgtgacgcgg acgccgtctt cgaccggctg
    14401 cagctcgacc acggtgagga agtcgtaggg gtcgacgccg gggatgaagt cggcgagcga
    14461 ggtgtaggag agcctgccgg gctcggacac ctccacgaac gtcttgcggg actcggtgtt
    14521 cagcggcatg ccgtggctct ccatgaacgc gatctgctcc ggcgcggtgg cggtcatcgt
    14581 gtagatgagg tcgccgccgg gccgcaggtc gagcttgccg acctcgacgg tgaagccgtc
    14641 gggcgaccac caggagacga tgccctccgg ggtggtccac agctgccaga cgtgctcggg
    14701 ggtggtgggg taggtgcggg tgatctgcac gcttgccatg gtgggctcct tgtgaagcgg
    14761 ttgagcgggt gatgaagccc caccctgcac cttgggtggc ctgcgcgaac agatgcggat
    14821 gtcactatgg gcgccgtgtg tttcgcgagt aggcggactt gagtagcgga ataggcccgg
    14881 aataggcacc gtcgcgacgg ccgttgcgtg tggggtggcg aacgccacga cggtggcgga
    14941 tgatgcgggg gccgtgtgcc ttccccgagg catcgaccgc ctgaccccaa ggagcggcgt
    15001 ttgcgtagcg actcggtcga tgtgtcccag aaggccgctt ccgcggttta tcccgccgga
    15061 gtgctggcgg cgtccccccg taccctcgtc gacgtcctcg acgagaccgc gcgcctgcac
    15121 cccgacgcgc ccgcgctcga cgacggcacc gtgtgctgga gctaccgcga cctgcgcgcg
    15181 gaggtgggcc ggatggccgc ggagctggcg gaggcgggga tcggccgcgg cgccagggtg
    15241 ggcgtgcggg tggtgtcggg gacggccgag ctgtacctgt ccatcctcgc ggtgctcgcc
    15301 gccggcgccg cgtacgtgcc ggtcgacgcc gacgacccgg acgagcgggc cgagctggtc
    15361 ttcaccgagg ccgccgtgga cgcggtcatc accgacaaga tcaaggtgct cgggggcggc
    15421 cgggacgacg gcggcccgcc cgcgccggac gacgacgcgt ggatcatctt cacctccggc
    15481 tccaccggca agccgaaggg tgtcgcggtg acgcaccgct ccgcggcggc gttcgtggac
    15541 gccgaggcgg ggctgttcct gcgggagcgg ccgatcggcc cgggtgaccg cgtgctggcc
    15601 gggctgtcgg tggccttcga cgcctcgtgc gaggagatgt ggctggcctg gcggcacggc
    15661 gcctgcctgg tgcccgcgcc cagggcgctc gtacgcaccg gcatggacct cggcccgtgg
    15721 ctggccggca agggcatcac ggtcgtctcg accgtgccga cgctggccgc gctctggccg
    15781 gccgagcacc tcgacgggat caggctgctg atcttcggcg gggaggcgtg cccgccggag
    15841 ctggccgcgc ggctggccgt gccggggcgg gaggtgtgga acacctacgg ccccacggag
    15901 gcgacggtgg tcgcgtcggc ggcgccgctg accggcgagc agcccgtccg catcgggctg
    15961 cccctcgacg gctgggacct ggcggtggtc ggcgacgacg gcgagccggt cgccatgggg
    16021 gagaccggcg agctggtcat cggcggcgcg ggcctggccc gctacctcga cccggtcaag
    16081 gacgccgaga agtacgcgcc gttaccgtcg ctgggctggg cgcgcgccta ccgcagcggc
    16141 gacctggtgc gggccgaccc ggaggggctg gtgttcgtcg gcagggccga cgaccaggtg
    16201 aagctgggcg ggcgccggat cgagctgggc gaggtggacg ccgcgttgca ggcgttgccc
    16261 ggtgtcaccg gcgcggcggc ggccgtccgt accgccgggg gcgggcatca gctcctcgtc
    16321 gggtacgtcg tcaccggccc cggcttcgac gccggcgagg cgcgcgacct gctggccgac
    16381 tcgctgcccg ccgccctggt gccgcgcctg gcgcccgtcg gcgcgctccc gacccgcacc
    16441 tcgggcaaga tcgaccgcga cgcgctgccc tggcccctga ccgggcgact cgccgtctcg
    16501 gagctgactc ccgctgaggc gcggctggcc gggcactgga ccgcgatcct gggagtggcg
    16561 ccggaagggc ccggcgacga cttcttcgcc agtggcggca cgagcctcgc cgcggccagg
    16621 ctggtgtccg tgctgcgccc cgaccacccc gacgtggcgg tgggcgacgt gtacgcgcac
    16681 ccgacgctgg ccggcctggc cgcgctcctg gccaccaggg gtggctccga ggccgcccgc
    16741 ccgcccgtga cgcccatgcc gcgccgggcc gcgacggtcc aggcgctgct catggtgccg
    16801 ctgctcacgg ccggcgccat gcgctggatc gtccccctgg ccgcgctcgg caacgtgctg
    16861 gccgcgccgt gggcgcccgc gctgtcctgg tggtgggtgg cgctgggcgc gctggcgttc
    16921 ctcaccccca tgggccgggt cggcctgtcg gcggcgctcg cccggttgct gctgcgcggc
    16981 gtacggcccg gcagccatcc gcgcggcggc ggcgtccacc tgaggttgtg gttcgccgag
    17041 cagttcgcgg ccaggctcgg cgtgccggac ctcgccagcg cgcccctgat gacctggtac
    17101 gcccggctgc tcggcgcgca ggtgggcgaa gacgcggacc tgcactcgcc gccgcctgtc
    17161 acgggcctgc tcaaggtcgg caggggcgcg tcgatcgagc aggaggtgga tctcagcggg
    17221 cactggttcg acggtgacgt cctgcacgtc ggcgagatca ggatcggcgc cggcgccacg
    17281 atcggctccc gctccacgct gctgcccggc gcgaagatcg gcaagaactc gcaggtggcg
    17341 cccgggtcgg cggtcgccgg cgcggtgccg tccggcgagc tgtgggccgg cgtgcccgcg
    17401 ttccgccagg gcaggtcgcg caagccgggc gagcgcgccg cgcgttcccc ctggtggacc
    17461 gccctgtacg gggtgaccgc cgtggcgctc ggcctcctcc ccgtcgctgc cgccggggcc
    17521 gccttcgcgg tcctggcctg gtccgcccgc gaggcgcgta cgctcggcgc ggcgctggcc
    17581 gccgccctgc ccggcgtgcc gctcgcgacg gtcaccggca tggccgcgtt cgcgctgctc
    17641 acgctggcca gtgtgcggct gctcgggctc ggcctgcacg ccgggcagca cccggtgcac
    17701 agccggcagg cgtggcaggc gtgggcgacc ggccggctga tggcctccgc ccgcgtctgg
    17761 ctgttccccc tgtacgcgag cgtcctgacc ccggcgtggc tgcgggcgct cggcatgaag
    17821 gtgggccggg gcgccgagct gtccacggtg ctcgcgctgc ccacgatgac gtccgtcggc
    17881 gacggcgcct tcctggccga cgacacgatg gtggctccgt acgagctcga cggcggctgg
    17941 atgcgcatcg cgaccgcgcg gatcggcaag cgcgccttcc tcggcaactc gggcatgacc
    18001 gcccccgggc gcaaggtgcc caaggacggg ctggtcggcg tgctgtcggc gacgccgaag
    18061 aaggccaagt cgggctcgtc gtacgtcggc atgccgccca tgaagctgcg ccgcaccgcg
    18121 gaggagggcg acaggaaccg cacctacgac ccgcccgccc ggttcaaggt ggcgcgggcc
    18181 gtcgtcgagg cgttccgcgt ggtgcccgcc atggccgcgg tcgcgctcgc cgtcctggcc
    18241 gccgccgcgt tcgaggccgt cgccgcccgg tacggcttcg cggcggcgat cgccctgagc
    18301 ggcgtgatca tggcggtcgc cggcgtggtg gcggcggcgg tcgccacggc cgccaagtgg
    18361 ctgctggtcg gccggatcgg cgcgggcagc cggccgctgt ggagctcgtt cgtgtggcgc
    18421 aacgagctgg cggacaactt cgtcgaggtg ctggccgcgc cctggttcgc ccagccgtgg
    18481 ctgggaaccg cgccgctgaa cgtgtggctg cgctccctcg gggcacgcat tggacatggg
    18541 gtcacgtgtg acacgtactg gctgcccgag gcggatctgg tgaccctcgg cgacggcgcg
    18601 tgcgtcaacc ggggctgcgt cctgcagacc cacctcttcc acgaccgggt catgagcatg
    18661 gacaccgtca ccctcgacgc cggcgcgacc ctcggcccgc acggcgtggt gctgccggcg
    18721 gcgcgggtgg gcgccgacac cacggtcggc cccgcgtccc tggtcatgcg gggcgagcac
    18781 gtgcccgatc ggacccgctg gttcggcaac ccggtctcgg catggcgatg accgagcaga
    18841 tccacagcac cccgcacctg cccggggacc cgtacttccc cgcgcacggc gaccaccgct
    18901 acggcgtctc gcactacgac ctgaggctga cctaccgcgt cgccgccaac cggctcgacg
    18961 gcaccgccct gctgacggtc acggccgccc agcccctcag cgcgctggag ctggacttcg
    19021 cccagctcag ggtcgcgggc gtcacggtgg acggcctgcc cgcccgctac gcccacggcc
    19081 ggggcaagct gcgcgtgaca ccgtcccggc cgctggccgc gggggagcgg gtcgtcgtgg
    19141 gggtgcggta ctccggcaag cccgtgccgg tgccgagccc ctggggcggg ctgggctggg
    19201 aggagctgag cgacggcgcg ctcgtcgccg gccagccgat cggcgcgccg tcctggttcc
    19261 cgtgcaacga ccgtcccggg gacaaggcgt cctaccgcat ctccgtgacg acggccacgc
    19321 cgtaccaggt catcgcgaac ggcgcgctgc tggccaggcg gcgcggcgcc gggaacacga
    19381 cctggatcta cgagcagccc gagccgatgg cgacctacct ggccagcgtg cagatcggcc
    19441 gctaccagat ctccgagtac ggcggcgccc ggctcgccca cccgccccgg ctggccaccc
    19501 gcgtccgcca cgacttcgcc cggcagggcc agatgatggc gctgttcggc gacctgttcg
    19561 gcccctaccc gttcaccggc tacacggtcg tggtggccga cgacgacctg gagatcccgg
    19621 tcgaggccca gggcatgtcg atcttcggcc gcaaccacgt ggacggcgtg cgcggcggtg
    19681 agcggctggt cgcgcacgag ctggcccacc agtggttcgg caacagcctc accgtggccc
    19741 gctggagcga catctggctg caggagggct tcgccacgta cgccgaatgg ctctggtcgg
    19801 agtcgtcggg cggcccgccc gccgccgagc acgcccggcg ctggcggcac cgcctcaccc
    19861 agctcccgca ggacttcgtc ctgtccgacc cgggcgcgcc ggccctgttc gacgaccgcg
    19921 tctacaagcg cggcgcgctg acgttgcacg cgctgcgcgg ggcgatgggc gacgagccgt
    19981 tcttcaccgc cctgcgtgcg tggaccgccg cccaccgcca cggcaccgtc accaccgggg
    20041 agttcgcgga gcacgtgcag cggcacacag accgcccggt cgccccgctg ctgtcggcct
    20101 ggctgcacga ccgttcgctg cccgacctga cctgatcgcc ggcaggaatg gcgagcgggc
    20161 gggggttgtt ggtggtgagc atgtcggacg agactgtaga gctgagcccc agcgactggg
    20221 tgcgggacca gacgaagaag atccttgaga ccggcaccac cgagggcatc gacatcgccg
    20281 ggtcgccgat cgtgctgctg accctgcgcg gcgccaagag cggcaagctg cgctacacgc
    20341 ccgtgatgcg ggtggagcac gagggccggt acgccgtcgt ggcgtccaag gggggcgctc
    20401 ccgagcaccc cacctggtac tacaacatca aggcgcaccc cgagttcaca ttgcaggacg
    20461 gcaccgtcac caagcggtac gtcgcgcggg aggtcgaggg cgcggagcgg gcggagtggt
    20521 gggagcgggc cgtcgcggcc tatccggcct acgccgagta ccagacgaag accgaccggc
    20581 agatcccggt gttcgtcctg gacccgaagg agtgacccgg cgcggccggc ggcacgccgc
    20641 cgccggtcgc accgcgaagg tcagtcgagg gagccgaccg tcacccgcca ctcccgcagg
    20701 gtgcggtcct tggtgacgtc gagctgcgtg tacgggtcct ggtcgacgag cgcctgcgcc
    20761 gccgcctcgt cctccgcccg cagcacgatc atgccggccg tcaggtccgt gtacgggccg
    20821 gccgcgacga cggcgccccg ctcccagagc ttgttcaggt gggccaggtg gtcgtcgcgg
    20881 cgctccgcgc gcagcggggt gtcgttgtag ccgtaggtca ggacgaacag tgccattcct
    20941 gggtactccc ttttgttgat gtcagccttc gttgatgtca gccgccgagc ccgtacaccc
    21001 gccgggcggt gccggcgaag acggcgtgcc ggtcggcggg cggcaggtgg gccagcgcgt
    21061 ccttccacgc gccgaccagg tgcggcatgg tggtccagag ccgctcgacc gggaagttgg
    21121 tgccgaacat ggcccggccg gcgccgaagc gggcgagcac ctctccggcg acgaaggaga
    21181 tcagctcggg gtccacgcgg tggacgaacg tgccctggcc ggtgagcttg acgaccacgt
    21241 tcggcagctc ggccagcgcg gacagcccgg cgcgccacgg ctccacgtac tcctcgccga
    21301 tgagcatgcc cgcgtgcacg agcacgaagg tgaggtcggg gaaggccgcg accaggtcgg
    21361 ccgcgtccgc catctgctcg gggaagacct gcagctcgaa cagccagccg aggtcggcga
    21421 ccgcgccgag gttcttgcgg agcaccgggt ccttcatccg gtcgggcgcg gtcgcgaagc
    21481 ggaactccgg gcgttcgtgc cagtgcagct gctgccggat gccccggacg agaggggtga
    21541 gcgcggcctg ccgccgcagg acccgcggcg tgtcgtcgtc gaacaggtcg gccgccgcga
    21601 cgaccgccga cggccggccc gtctcctcgt ggacgtcgcg cagccagcgc acctcgtcca
    21661 cgacccggtc gagcggccag ttcgtctgga cgtagacgga ttcggtgatg ccgcaggccg
    21721 tggcatcggc ggcgtactcg tcgatcaggt agtcgcgcct gatcgcctcg tacggcccga
    21781 agatgcgcgg caccatcggc ccggacagcc acggcaggtc ggcgacccgc cagatgtggt
    21841 ggtgcgcgtc gacgatgtcg cccgagtagg gggccgcttc cggcatggtg atcactccct
    21901 ggccaaggtc tgtacctgct cgtacgccgt ccgcaggtcc cgtacgcccg cgagcgcgtc
    21961 cacgctgccc agcacggccg ccatgccgcg ggtgaccggc tggtacgccg ggtcgcaggc
    22021 gagcggcgtc caccacagca accggtggcc cagcagcgac aaccggcgca cggcggcctc
    22081 catgggcagg gggtcgccgc gttccagccc gtcggacagc acgatcacca gggcgccgcg
    22141 cgccatcgtg acgtggcggg cgttgccgag gaactcctgg agcgaggggc cgatccgggt
    22201 gccgccctcg gcgtccagca cgacctcgct cagcgcggcc acggccgcgt cgacgtcccg
    22261 cgcccgcagc ggctcggtga cgcgggtcag ccgggtgccg aacgtgaaca cctcgacgcg
    22321 gtcgaggcag ccgaccatgg cgtgcgcgaa gcggaggtag gcggcgctgt gctgcttcat
    22381 cgaccccgac acgtcgatga gcagcagcac ccggcgctgc cgccggggcc ggttgcgccg
    22441 ccgcagcgtg acgatctcgc cgtggctgcg gcgggactcg cggcagatcc tggcgacgtc
    22501 gatccacggg ccgcggcggg cgggccggcg gcggcgggac cgtaccgtgg gcacggcgcc
    22561 gcgcagctcc cggcgcagca gcgcgagcac ggcccgctcg tcccggctcg cggtcccgaa
    22621 cgcggggcgg cccacgcgct cggagaagcc ggcctccagg cccgcctccc cgcccggcgc
    22681 cgccgcgaag ggcgcctcgt cgcccttccc gcgcggcgcc ggctcctcct cgtccgggaa
    22741 ctcccgctcg gggacgggcc gcgcgcgggc ggccccgaac cagcgctcga acgtggggga
    22801 gtacacctcc aggtccgcgc gggaggcggt gagcgtgctc gccccgatcc agtacagctc
    22861 cgtggcgtcg cgcgggccgg cggcctcgat cgcctggagg aagacccgct gcttggacac
    22921 cgggacgcgc aggccctgcc cgtgcaggtc ccgcaggaac ccgtgcacgt gctcgcggac
    22981 ccgcgccacg agggcccgct cagtcaccga acacctccgc ggcgtgccgg ccgaccagcg
    23041 acaggtcctc ctcgtacttc acgagcagcc ccgccgacct gcgcatcgcc tccagccagc
    23101 ccgccccctc gcgggtcagc gcctgcacgc cgcgcgccca cgacgtggac tccgcgatgc
    23161 cgggccgctt cagcagggcc agccccctga tccggtgcac ggcggccacc aggcgggccg
    23221 cgctgcgctc gtccaggccg ggcgcctgcg cctggatgat cgcctgctcc cgctcggcgt
    23281 ccgggaacgg gatccagtga tagaggcagc ggcgcttgag cgcgtcgtgc agctcgcggg
    23341 tccggttcga ggtgaggatg acgaacggga cgctcgccgc cctgatggtg ccgatctcgg
    23401 gaatggtgat ctggaagtcg ccgaggaact ccaggaggaa cgcctcgaac tcgctgtccg
    23461 cccggtcgat ctcgtcgatc agcagcaccg cccccgacgc cgcccgcagg gcccgcagca
    23521 gcggccgttg caggaggaac tcctcccggt acaggtcgcc gacgccgcgt ccctccacct
    23581 cggccgcccg cagcgacagc agctgcttcg ggtagtccca ctcgtacagg gcctgggagg
    23641 cgtccaggcc ctcgtagcac tgcaggcgga tcagctcgcg cccgagcacc cgcgccaaca
    23701 cgttcgcgat ctccgtcttg ccgacgcccg gctcgccctc cagcagcagc ggcagcccga
    23761 gcaggcccgc caggcggacg gcggtgagca ggccctcgtc ggcgaggtag ccctccgcgc
    23821 ccagccgccg gcccagcgtc tcctggtcag ccagcacggc cggccctcag ctcgtccagc
    23881 ccgcgcagca ccttctccgg cgtgaacggc atgctggtca gccgcacgcc gaccgcgtcg
    23941 aacacggcgt tggcgatcgc ggggatcggc gcgttcgccg tcatctcacc gatccccttg
    24001 gccccgaacg gcccgttgcc ggccggccgt tcgaggaaca cgctcgtctg ctccggcagg
    24061 tccgccggcc ccggcatcaa gtacgcggcg aagtcgagcg ggccgtgctc gcgcgagtgc
    24121 ggatagtacg gctccgtcga ctcgaacaac gcgtgcgaca accccatcca cgcgccgccc
    24181 tcgacctgct gcgtcgcgat ggccgggttg agcgcccggc ccacctcgta ggtgttgtag
    24241 agccgcagca cctcgatgac gccggtctcg tcgtccacct cgacctcggc caccgtgcac
    24301 gcgtgcgcct ggcaggagtc ggggtccatc tcgcccgtct ccggcaccgg cgtgctcggc
    24361 tccttgagga agatgccccg ccccgagatg gtccggccct gacggaagtg agcggccagc
    24421 gccacctcgc tgacgtggat cttcttctcc ggcgccccct tcagccggac gaagcccgtg
    24481 ccgtcggtct ccaggtcctc cgcgtccacc tccagctcgt cggcggcgac ccgcagcagc
    24541 acctccctgg cctcgcgggc cgccatgatc accgcgttgc cgacccggtg cgtgccgcgg
    24601 ctggcgaacg tccccatgca gtgcgggccg gtgtcggtgt cggccgtgtc cacgatgacg
    24661 ttctccagcg ggacgccgag cgtctccgcc gcgcactgcg cgacgaccgt ccgcagcccc
    24721 tgcccgaggt ccaccgagga gagcgtgacc acgaacccgc ccatggtcgt ggcgtgcacc
    24781 agcgcctgcg acgggtcgcc gcccaggttc atgccggtcg ggtagttgac cgccgcgtac
    24841 ccgcgcccct gccgtatcgc catcgctcag ccctccggtc gctcggccga tgacatcgcc
    24901 cggtactccg gcggcaggtc gtgccccacc aggtccgccg cgctctggat cacctcgacc
    24961 agcgccgtgc cggacgcgat cttgcggtgg gccttcatgt cgccgtcccg gtaggcgttc
    25021 ttcagccgca gccgcagcgg gtccatgccc agctccctgg cgacgtggtc catgtgcgac
    25081 tccagcgcga agtcgccgat cgtgacgccg aagccgcgca tggcgctgga cggcgtccgg
    25141 ttcgtgtaga cgcagtagca gtccacgtgc acgttcggga tcgtgtacgg gcccggcatg
    25201 tgcgccgccg ccttggtcgt gccgtacggg ctgtgccgcg agtacgcgcc cgcgtccacg
    25261 tacagggtga cctggcgggc cacgatccgg ccgtcgtcca tgacgccgtc cttgatgtgg
    25321 atgtgctcgg ccgcccgcgt cgacgacacc tgcatctcct cggcgcggct gtagacgtac
    25381 ttcgcgggcc ggcccgtcag catcgcggcc aggcacgcca gcggctcgac gatgacgtcc
    25441 accttgccgc cgaacccgcc cccgaccgtg ccgcccacga cacgcaggct cgtgggcggg
    25501 acgcccagga tgagcgccgt gttgtcgagg gtgaagaagg ccgcctgggt gttgctgtgg
    25561 atgcgcagcc ggccgtcgcc ctgcgggacc acgatgcagc cggtcggctc gaccggcgcg
    25621 tgctcgatgg gggaggagct gtaacggccc tcgatgatcc ggtccgcctc ggcgaagccc
    25681 cgctcgacgt cgccgaagcg gatccggcgg cacgggtgcc cctcgtacac gaagtggttg
    25741 gtgcccgcct gcttgatgat cggcgccccg tcggccagcg ccgcctccac gtccaggacg
    25801 gcgggcaggt ccgtgtagtc gaccacgacc cgggcggcgc cctcgcgcgc ggcctcctcc
    25861 gtctccgcga ccacggcgac gatcggctcg ccccggtaga gcacccggtc ctcggccagg
    25921 accggctcgt cgtccgggcc caccccgatc aggcgcagca cgacgtacca gttgttcggc
    25981 acgtcctcgt gggtgatgac ccgcagcacg cccggcacct ccagcgcgcc ggagacgtcg
    26041 acccggtcga tgcgggcgtg gtgccgcgtc gagcggtgga tcttgacgtg ggtcaggccc
    26101 ggcggcgtca ggtcctcgaa gaacagcgtg cggccggtga cgtggccgcg ggcgtccgag
    26161 cgctggaccg ccgagccgat gacggtgaag tcgcccgcgc gctcgtcctt gaagtacgtg
    26221 gtgtcgatcg gcgtgaggcg gcccatcagc cggcggcctt tccggagagc ggcgcggcgg
    26281 cgtcgcggtg tcgttccccg gcgccgtcgt ggcggcgttc cgcggcgctg tcgtggcggc
    26341 cttccgcggc gccgtcgcgg cggctttccg cggccgacag gacggcggtg acgatcggct
    26401 cgtagccggt gcagcggcac acgttcccgc agatcgcctc cgtgacgtcc tggcgggtcg
    26461 gcgccggctc ccggttgagc agcgccgtcg ccgacatgat catcccgggg gtgcagaagc
    26521 cgcactgcgt cgcgaagtgg tcgacgaacg cctgttgcac gtcatcgagc cggtcgccgt
    26581 cggccagccc ctcgaccgtc tccacggcgc agccgtcgac cgtcacgacg gggatcaggc
    26641 acgagaccgc gggccggccg tccagcagca ccgtgcaact gccgcagccg ccctgcgcgc
    26701 acccgcgctt ggcccccgtc aggccgaacg tgtcgcgcag ggcgctcagc aacgtcgtgg
    26761 acgggcgggc gatcagctcc cgctccgtgc cgttcagctt gagggtgacg atggtcgagg
    26821 gcataggctc ccctttcagg ccccgagcag ggcacgacgc aggtggacgg ggtagacccg
    26881 ggcgcggtac cacgcggagg cgtaggcgtc gtcgaacggc tcgatgacgt ccgcccccgc
    26941 cgcctcggcg acgacctcgg cggtcagcgg cgcgccccgc agcacgcgct cggcgcccgc
    27001 cgcccgcagc aggcggcgcg agagaccgcc gagcaccagt cgcacgtcgc cgaccaggcc
    27061 gtcctcgacc gtgaggcggg cggccaccgt gacgatggag cccgagttca gccgccgccg
    27121 gctcgccttg tggaagcgga acgtgcccgg cgccggagcg gtgaaccgga tcctcgtcac
    27181 cagctcgcct tcgggcaggc cgtccgcgac cacccgctcc agccgctcgc ggcgcaggcc
    27241 ggccgtgccg agcacgtcca gctcggcgtc cagggccagc agggcggcgg ccaggtcgcc
    27301 gtacggctgc ggcacgaaga ggttgccggc caccgtggcg agggtgcgga ccggcgggga
    27361 ggcgatcgag cgcacgcacc ccgccaggta gcccagccgg gggtcgtcct ccaggtcggc
    27421 gagggtggtg gccgctccca gggtcaccgt gtcgccgtcc acgtcgatgc cgcgcagccc
    27481 cgccttgcgg aggctgacca cccgcaggtc ggggcctgcc tcgtcgttca tcctggtcag
    27541 gaggtgggtg ccgccgccca gagggacggc gcccgcctgg aggctcgcgt gagccgcttc
    27601 ggcgctgtct ggcatctcaa ccgatatcag cattcgcgct cccattatcg atatcgataa
    27661 ttggagagta gatggcatga tcggagagtc aaggcccctc tttcgacatc gggaggctcg
    27721 ttgccggaac ccacgggcaa cctcggccct gcccagcccg gggcccagcc cggtgcccag
    27781 cccggggccc agcccggggc ccagcccgcc cctccgcctg cccctcagtc ggctgggccg
    27841 cgttccgcgc ggccgaccct gagccggcag atccgtgacg ggctcctgcg ccggatcgtc
    27901 tccggcgagc tcggcgaggg tgaccgcctg atcgagacga agatcgccca ggagttcggc
    27961 accagccagg cccccgtgcg ggaggcgttg cggcagttgg aagggctcgg cctcatcgag
    28021 agccagcccc gccacggcag ccgggtgctg ccgttcgtcg agcagacgat ccgggaggcg
    28081 tacatcctgc gggcggccct ggaggagacc gcgacccggc tcgccatgct ggccggcacg
    28141 ctgcccttcg accttctgca ggaggcggtc gaggagatgc gccgatgcgc ccgcgacggc
    28201 gacgtgcccg gcatcggcct ggccagcgcc cgcttccacc ggcacgtcgt gcaggccggc
    28261 ggcaacgcgc tgctgacccg cgcctgggag gcgctgcaga tcgaggcccg caccgccatc
    28321 gccctcatgg tcacggggcc cgagctggag cgggtggccg aggagcacca cgagctgctg
    28381 gacgtcatgc gcgccgggga cgtcgagacg gcctgccggc acgcccgcga ccaccagtgg
    28441 gcctacgccg acacgcccca cgacccgtac gggaccccga gaggcgggca tcgcgacacg
    28501 tgacgggcgc gcgggctctc ggttgcgtca gggcgtgccc ggctcgtggg gtggcggctc
    28561 gtccgttccg tcgcggtcgg tgaggtcgga caggagccgc atccccgccc cgtccaccga
    28621 acgcgcgtcg gcgctgagga cgacgacggc ggtccggcgc tcggggatca cggccagcag
    28681 ggagcggtag ccgccggtgc cgccgttgtg gaacagcacc cgcggcccgc ccttgtcccg
    28741 cgcccgctcc accgacaacc accccgcgtg cgcggtcgag acgccgctga tcgggtggcc
    28801 gacggcgcgg gtccgcgcga cggcctcggc gatctccgcc gggccggacc cgaacgtggc
    28861 cgccgccagc cgcagcaggt cgtgcgccgt ggagtgcagc ccgcccgcgc ccgccagggc
    28921 cgccagccgc catcccgggc ggggccggcc ggaacgcgag tgcccgggcg cgagccgcgc
    28981 ggcccgctcg ccgtcgagca ccacccgcgt gtccgccagc ccgagcgggc ggcagatctc
    29041 ccgctggacc agctcgtcgt agcccagccc ggtctgcctg gccagcgcca gccccagcag
    29101 ccccccgccg aggttggagt agcggaaccg gctgccgggc acggaccgca gccgcgtcct
    29161 ggccagcccc gccagcagca cctcctcggt gcagccggcg taggggtcga gcgagaacag
    29221 ggcgcccggc atcagcccct tgggcagccg gggcaggccg gaggtgtggc aggccaggtg
    29281 caccagctcg atctcccggc cgtcgcgccg cggcacggcg gccccgtccg gcagcagctc
    29341 ccgcacgggc tgctcgaagg cgacctctcc gcgcccggcc agcctggcca gggtgagcgc
    29401 ggtgaacgtc ttggtgatcg agccgatctc gaacacggtg tgcgggccgg cgccgtgcgt
    29461 cgcgcgctcc tcgccccgga tcgcgccgac cgcgaccgct ccccgccgcc gggcggccag
    29521 ctcttctgcg gtacggcgga cgaggtcgtc gaggggcgcg tcggtcacgg cgtcaatgtt
    29581 ggttgacggc gatgtcgcgt gtcaacccgc ggccgtacgg ggacgtgatc gtgcacagga
    29641 cggtgaaacg tgcatgatcg tgcagcaggg tcagggggcg tgaatgacgg ggatgccgag
    29701 tgctcgtacc gtggcgttgc cggcgtcggc gtccgtgatg acggcggcca cctccgtcag
    29761 gggcaggacc gagaagcggg aggcggcgcc gatcttctcc gagctggcca gcacgtacgt
    29821 gtcggccgcc tgccgggcca gcgtgcgttt catcgcggcc tcgtcggcgt cgtccgtggt
    29881 caggcccgtc tccgggtgca cgcctgtgac gccgagcagg aagaggtcgg cgttgacgcc
    29941 gcgggccgcc tcgaccgcgg ccgcgccgca ggagaccatc gagtgcttga acagccggcc
    30001 gccgatcagg tagacctcca cgtcgtggtg ctcggccagg gcgccggcca ccgtcgggct
    30061 gtgggtgacg acggtggcgc gcaggtcggg cgggagggcg cgggcgacgg cgagggccgt
    30121 ggtgccgccg tcgatgatcg cggtgctgcc gggcctgacc agcgcggccg cggcggcggc
    30181 cacccgctgc ttgccggaga cctcgacgcc ctggcgggtg gcgtagtcgg cgatcgcggg
    30241 ggaggcgggc agggcgccgc cgtacacccg ctggcacagg cccgcggcgg cgaggtcacg
    30301 caggtcgcgg cggatgctgt cttccgacag gccgagctcg gcggcgaggt ccttggcgat
    30361 gatcttgccg tcgcgggcga ggcgttccag gagcagctcc cggcgttgcg cggccagcat
    30421 gcacgtttct ccttgttctt tccgatttct tcgtattata gtcccatccc atgatgattc
    30481 tcattgccgg cccgtaccgc tccggtacgg gcgacgaccc cgaactgatg gcacgcaacc
    30541 tggcccggct ggaggaggcg gcgtggcccg tgttccgcag cgggcacgtc ccgatgatcg
    30601 gggagtgggt cgccctgccc gtgctgcgcg gggccggcgg cggcgggccc gccgaccccg
    30661 tcgccgagga gatcatgtat ccgacggcgg agcggctgct gcggcactgt gacgcggtcc
    30721 tgcggctgcc gggggagtcc gccggggccg accaggacgt gcggatcgcg accgagcgcg
    30781 gcctgcccgt ctactacagg gtcgaggaca tccccggcta cctgtagctc cggtcagcgg
    30841 gtggcgaagt cctgcgtcca gtaggtctgg ccgctggagt ccttcgccgc gcccacgccg
    30901 atgtgggtgt aggagcagtt catgatgttc tcccggtggc cggcgctgtt catccagtcc
    30961 cggaccacct gggcggccgt gcgctgcccc ttcgcgatgt tctccgccca ggccgagccc
    31021 gagaagccgg tcgcgcggat gcggtccacc atgtcgcggc cgtcctgcga gtcgtggtcg
    31081 aagtagccgc gcttggccat gtcggcggag tggccgaacg ccgccctgcg caggcgcgcg
    31141 tccgggcgga gcgggtcgca gccgcccttg gcccgctcgg cgttggtcag ccggacgacc
    31201 tcgctctcca gcgccgtccc ggcggacgtc gcctgcgccg ccgtcttccg gggtgcgggg
    31261 gtgggcgtgg ccgtaggggt gacggtgggg gtgggggtcg gggtggcgca ggtcagacgg
    31321 acggccttcg aggtggcggt gtccgtcgag tagtcggtcg cgaccgcgta gtaggtgccc
    31381 ggcttgcagg gcgtcttcag ggtgatgcgg tccttcctgg ccgcgccgct cttcacgacc
    31441 gggtcctcgc cgggtacggc gcgcttgatc cggatgcgca gcagcgccgg gcggacgcag
    31501 tcgcggcgga cggccgaggt ctcgatcgtg agggcggtga cgtccgggcg ggccacggtg
    31561 acgcggcact tgtccgattc gggggccggc ttgggggtgg gtgtcgtggc cggggtggtg
    31621 ggcgcgtccg cctggggcgt gaccgccgcg gagggggcgc cctgcgtgct gccggtggac
    31681 ggggcgcagg cggccaggcc gagcacggcg gcgagcaccc cgaggggttt gcgcatggga
    31741 ttcctccaga tccggaacac gctggacgtc ccgcatcttg ccatgaaaac ggacaatccg
    31801 cccattgtgg ggttttctgg tatcgagttc catgggtgcc ggggggctgg agcgatggtt
    31861 cccggccggt gtcgcgatgc tgcgaactgc ttcccctgta taccgacatt cccgctatgg
    31921 tgctgaagat ccgttgatgc cgttatggga gagtcatgcc gcaggcccaa ccgctccggg
    31981 aggacgatcc ccccgccgtg gggccctacc ggctgctcgg acgcctcggg gcgggcggcc
    32041 agggcgtcgt ctacctgggg caacgaccgg acaccgcgct ggtcgcgatc aaggtgctcc
    32101 gcgacgggcg gggcgacggg cggctggcca aggaggtcga ggcggcgcgg cgggtggagc
    32161 cgttctgcat cgcccaagtg ctcgacgcct cgctgagcgg gccccggccg tacatcgtga
    32221 ccgagtacgt cgacgggccc tccctccagc aggccggccg gcacaccggc gccgacctgc
    32281 agcggctcgc ggtcgcgacg gcgaccgcgc tggcggccat ccaccaggcg ggcatcgtgc
    32341 accgcgactt caagcccgcc aacgtgctgc tcgggccggg cgggccgcgc gtcatcgact
    32401 tcggcatcgc ccgctcggcc gactccgggc cgtcgggggc cagcggggtc atggggacgc
    32461 ccgcgtacat ggcgccggag cagctcgccg gagcgccgat cgggccggcg gcggacgtgt
    32521 tcgcgtgggg ctcggtgatg gcgttcgcgg ccaacggggc tccgccgttc ggcgaggaca
    32581 ccctgcccgc cgtcatcaac cgcatcctgc acaacgagcc gcagctcggc gacctgcccg
    32641 agccgctgcg caccgtggtg ctgcactgcc tggccaagga tccggcgcgg cggcccagca
    32701 tgcgggacgt gctgctgcgg ctgctcggcg gcgcccagca gcagcccgcg gccgtgggct
    32761 cgccggcgcc tcctcatccg ggcgcggtcg gggcgccgca gatgatggcc ggtcgaggtg
    32821 ggggcgcgtc ctggcccggg gatgcggggc cgccgacggc gccccggcac ggggcggggc
    32881 ggatgtggct ggtcgcgggg gtcgccagtg cggtgacgct ggtggtcgtg agcggggtcg
    32941 cctggggggt cacgaacgtc tggggggagc ggcctccgag ttcgagcccg caggccctgc
    33001 ccgcgacgac gaccgaagaa cccggcccca cggccgaacg caagcgcccg aagcgcaccc
    33061 gcacgccgca cccgacccgc acgccgtccc ccacccgcac gccgtccccc accccgagca
    33121 ggaagagcaa ggagccgacc gtcgcgccca cgacgcggac ggcgcggccc accaggacgg
    33181 ccgccgaggg cggtggcacg ttgcggatcg tctcgctgcg ggcccagggc gcgcgaaccg
    33241 ccaacaccca ggactgccag gtcggccagt cgaacatctt cgccgtggtc gagggcacga
    33301 agctgcgtac ccagttcgac taccagtgga tcctggacgg caaggtcgtc gggcgctcca
    33361 cctcctacat cgccgaaagc cacacccagc aggtcatcgg cccgctggtc gagccggtcg
    33421 gctcccaccg ggtcacgctc cgcctgacct cgcccagcac ggtctcgcgg acgctgacct
    33481 tccggatctg ccccaccggg accgaatgat ggggccgctc agggaagggg atccggccgc
    33541 cgtcggcccg taccggctgc tcgggcggct gggtgagggc ggccagggcg tggtgtacct
    33601 gggggaggcg cccggcgggc ggcgggtggc cgtcaaggtg ctccaggacg ggtacgccgg
    33661 cgatcaccgc ttcgccaagg aggtcgaggc ggcgcggcgg gtggagccgt tctgcatcgc
    33721 gcaggtgctg gacgcctcgc tgggcgggcg gccgtacatc gtcaccgagt acgtcgaggg
    33781 gcccgcgctc agccaggcgg gccggcacac cggcgccgac ctgcagcggc t
//
