LOCUS       NZ_CP017717            44255 bp    DNA     circular CON 03-MAR-2024
DEFINITION  [Actinomadura] parvosata subsp. kistnae strain ATCC 55076
            chromosome, complete genome.
ACCESSION   NZ_CP017717
VERSION     NZ_CP017717.1
KEYWORDS    RefSeq.
SOURCE      [Actinomadura] parvosata subsp. kistnae
  ORGANISM  [Actinomadura] parvosata subsp. kistnae
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 13047416)
  AUTHORS   Nazari,B., Forneris,C.C., Gibson,M.I., Moon,K., Schramma,K.R. and
            Setedsayamdost,M.R.
  TITLE     Nonomuraea sp. ATCC 55076 harbors the largest actinomycete
            chromosome to date and the kistamicin biosynthetic gene cluster
  JOURNAL   Medchemcomm (2017) In press
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13047416)
  AUTHORS   Nazari,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2016) Chemistry, Princeton University, 20
            Washington Road, Princeton, NJ 08544, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUN-2015
            Assembly Method                   :: Celera Assembler v. Jun 2015
            Assembly Name                     :: SmrtPipe 1.87.139483
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 13:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 12,000
            CDSs (total)                      :: 11,919
            Genes (coding)                    :: 11,783
            CDSs (with protein)               :: 11,783
            Genes (RNA)                       :: 81
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 36 of 136
            Pseudo Genes (incomplete)         :: 98 of 136
            Pseudo Genes (internal stop)      :: 10 of 136
            Pseudo Genes (multiple problems)  :: 6 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:57:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 611190
            Orig. end                         :: 655445
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017717.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..44255
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..44255
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="terpene"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..25084
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25084
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15084]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15084
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(107..721)
                     /locus_tag="BKM31_RS02725"
                     /old_locus_tag="BKM31_02700"
     CDS             complement(107..721)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025605.4"
                     /locus_tag="BKM31_RS02725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02700"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_080036627.1"
                     /transl_table=11
                     /translation="MARSTPGVTRQRLIDEAVRLFCTRGYAATSVADIQAACGLTTGSG
                     ALYKHFPSKRALLEAAVRRNLERIAERGGETAVATGDPRADLERMARAVWEVIEQDREL
                     IRIMLREFDGFGELFEGMWQGVMAGVYAQGARWIEEQRERGNVECADPEATAAVLLASL
                     TYYPLLRLMIGHTPGDLGPERFLAAWAEHAAVTLRVRPHPS"
     misc_feature    736..750
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.88"
                     /tool="antismash"
     misc_feature    743..758
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.28"
                     /tool="antismash"
     gene            744..1661
                     /locus_tag="BKM31_RS02730"
                     /old_locus_tag="BKM31_02705"
     CDS             744..1661
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016228.4"
                     /locus_tag="BKM31_RS02730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02705"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_080036628.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.9e-10, bitscore:
                     39.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVFIAGGTGALGRHAVPALVAAGHEVTALARTPDKAAALERQGA
                     RPVRVSLFDRAGLASAFEGHDAVINLATAIPSMSRFMSTKALRANHRVRAEGSAAVASA
                     ALDAGVARLVQESVSMLYRDGGDRWLDEHAPVDHYPLTRGNFAAEASARRFADTGGGAA
                     VVLRLGWFYGPGAAHSEQLFAQARHHVAVVLGRPGGYVSSIHLADAATAVVAALAVPGG
                     TYNVVDDEPLTKRAYADALARAAGAVPWVRGPGRLAYAFGDRLTSLTRSLRVRNARFRT
                     ATGWAPRYPSAREGWLATARTLLS"
     gene            complement(1680..2963)
                     /locus_tag="BKM31_RS02735"
                     /old_locus_tag="BKM31_02710"
     CDS             complement(1680..2963)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013130701.1"
                     /locus_tag="BKM31_RS02735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02710"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_080036629.1"
                     /transl_table=11
                     /translation="MTTSPPKRTEGAAAIREAASIREAAADLDAEGAGAVTRLLRSLPA
                     RPRLLGLGEALHDERPVHELRNEIFRELVEHEGYRAFAIESDCVAGLVVDEYVRTGAGS
                     LDDVMRTGFSHGFWDREATRELIRWMRAWNESHPDGDRLRFFGFDAPLEMMSAAGPRHT
                     LVALHAYLTAAGVAVPCTRDRLLALLGPDERWTNEAAALDPSQSVGHSPDVAELRLLAD
                     DLVPLLTVHAPRLIPATSREEWERAHLYARTATGLLRYHTIMADPAPERVVRMLGLRDA
                     MMADNLEAIAPHGPALVFAHNRHLQREASRWQLGDLTLEWWSAGAITSARLGTGYAFLA
                     SALGTVPHQGLDLPDPRTIEGMLATLLGERYVLDSRRLTTAVREAELIQRTDTAANHGY
                     FPLDPGELDKTDGLIFLKNVRAPGPEAP"
     gene            3057..3797
                     /locus_tag="BKM31_RS02740"
                     /old_locus_tag="BKM31_02715"
     CDS             3057..3797
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546446.1"
                     /locus_tag="BKM31_RS02740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02715"
                     /product="TioE family transcriptional regulator"
                     /protein_id="WP_080036630.1"
                     /transl_table=11
                     /translation="MPRGRLRPVDLAREHGLSTQAVRNYEEAGILPAAARTEHGYRTYT
                     ARHAQALRAFLALVPAHGHATATSIMRAANEGATEEALRLIDESHAQLLEDRRTLEAVE
                     QALRSLVPPPAPSAEPSRAPSPAPKAEPGVTFIGPLARKLGIRPATLRKWEQAGLVEPR
                     RDPATGYRVYSAADVRDAQLAHQLRRGGYLLEQIAPLIRQVRAAGGLAPLESALRDWQE
                     RLSARGRAMLRGAAALHTYLDEQE"
     gene            3844..4374
                     /locus_tag="BKM31_RS02745"
                     /old_locus_tag="BKM31_02720"
     CDS             3844..4374
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009085823.1"
                     /locus_tag="BKM31_RS02745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02720"
                     /product="DUF4240 domain-containing protein"
                     /protein_id="WP_080036631.1"
                     /transl_table=11
                     /translation="MDTTRYWQLVEDARAGAKDEWEVAARLSERLSALPPAEIIAAQQA
                     FWDLMTASYRAPLWGAAYMINGGCSDDGFEYFRGWLVTQGREVFEQVVADPDSLAGLPV
                     IQEAAADWTEKHCEAMLGAAYNAYRAATGEELPHGSYTIRYPALDPGWGFDFEEQRDEL
                     SRRLPRLAALYGR"
     gene            complement(4379..4909)
                     /locus_tag="BKM31_RS02750"
                     /old_locus_tag="BKM31_02725"
     CDS             complement(4379..4909)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024952.4"
                     /locus_tag="BKM31_RS02750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02725"
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="WP_222107502.1"
                     /transl_table=11
                     /translation="MSGGKAASRKAASREGETALVLGVPEAEPLVRPWRQREIGLPAHV
                     TVLTPFLPAPRIDDVVRRELRALFMRYPAVDVTFREIRRFTGEPGVVFLAPEPAKPFVR
                     LTEAVTGRWPGTPPYGGRYDEIVPHLTLGEDGAVDEAWVAGELPVTARVTAVSLLVRDA
                     GGHWRPTEVFPLA"
     misc_feature    complement(4874..4883)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            5100..5822
                     /locus_tag="BKM31_RS02755"
                     /old_locus_tag="BKM31_02730"
     CDS             5100..5822
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017603741.1"
                     /locus_tag="BKM31_RS02755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02730"
                     /product="DUF6882 domain-containing protein"
                     /protein_id="WP_080036633.1"
                     /transl_table=11
                     /translation="MHNSLTFTDLLDDAALLSLEHQVHLEEVLGGHSWQVDLQQPRFDF
                     ACVTRTITCTAFHLLGSAAPGPGTWLWAWANPSGFPEAVVAASARLRDFGLQYGIQELA
                     SAEVPFSALPGAPTEAHLAAGLLTEAAKAVTGRWTSYNGDAGGGTRAAFLVEHPDFRLP
                     PPEPARVMRVIQQALAGLRLTDHRRALHSYAVKRGLGADFSGEQGRITGPGFEAVVEFD
                     GYGRVAGIKAGLSAPHGG"
     gene            complement(5901..6488)
                     /locus_tag="BKM31_RS02760"
                     /old_locus_tag="BKM31_02735"
     CDS             complement(5901..6488)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133475.1"
                     /locus_tag="BKM31_RS02760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02735"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_080036634.1"
                     /transl_table=11
                     /translation="MVFARSERPRLPTAIKILVAGGFGAGKTTMVGAVSETRPLRTEEV
                     LTDRGIGVDDLTSVEAKRTTTVAMDFGRITLGNDYVLYLFGTPGQERFWFVWDELAEGS
                     LGAVILADTRRLADCFPSVDYFERRGTPFVVAVNCFEGAPTFELDEVRLALQLNPSIPI
                     IMCDARKRDSSREVLITLVKHSARLRAEPVGS"
     gene            complement(6469..6846)
                     /locus_tag="BKM31_RS02765"
                     /old_locus_tag="BKM31_02740"
     CDS             complement(6469..6846)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889885.1"
                     /locus_tag="BKM31_RS02765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02740"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_080036635.1"
                     /transl_table=11
                     /translation="MRGADEPTDEHWVDPEIIRPYVVTRGRTQPAHGRFDLISMALAVG
                     PPPGPDAGLDPEHLRILQLCREPKSVAEIAAYLDLPAGTIRVLLGDLFDRELVSAQEPR
                     SEVDMHDMKMYRAVLDGLRSL"
     gene            complement(6843..7262)
                     /locus_tag="BKM31_RS02770"
                     /old_locus_tag="BKM31_02745"
     CDS             complement(6843..7262)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011292472.1"
                     /locus_tag="BKM31_RS02770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02745"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_080036636.1"
                     /transl_table=11
                     /translation="MTPTAGTDLNWLMDDLVNRIKEAEHAIVLSSDGLLMASSAALQRT
                     DGEHLSAVASGLQSLAKGVSDHISAGAVRQTVVEWKNQFLIVTAAGERACLAVLCAQNA
                     DIGLVAYEMAMMVARVGQYLTSGARTAEAAARSDR"
     gene            complement(7259..9613)
                     /locus_tag="BKM31_RS02775"
                     /old_locus_tag="BKM31_02750"
     CDS             complement(7259..9613)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133478.1"
                     /locus_tag="BKM31_RS02775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02750"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_268966932.1"
                     /transl_table=11
                     /translation="MLLSLAALWVFAAWVTLREGVNLLWVSQLDSSVSAPSDPLLFALQ
                     RERRLSLTRLGDRAPQTRKELDKQRAETDTLHSAFREAADTTAVSWALDDEGEERLAVM
                     LKRLGSLKELRQSIDAGRLNRAQAANAYDDVIDPIYDVYGSLATLDDKELAKDVRSLLA
                     LSRARELLTREDALLAGALAEGRLSPATQAEFAQAVGRWRITAEQAARELPDFDRAAYD
                     KLIKGQSSVRLQTLEKQVMEHDPNSLTLPLTAEVWKATTERFLTDFNTMVLDAGDRVVD
                     RTIPVAVNVIIRLVLAGGLGLIAVVASIILSITTARSLLAQLQKLRDAAHELSDERLPG
                     IVERIGHGEEVDVAKEAPALDFGDDEIGQVGQAFNTVQRTAIAVAAEQAELRRSIRDIL
                     LSLARRTQGLVHRQLTVLDVMERRETDPEELKELFRLDHLAIRMRRNAENLIVLSGSSP
                     ARTWRRSVPMVDVVRGALAEVEDYTRVSLMPMGEVVLVGRAVGDVIHLLAELIENAVSF
                     SPPYTNVQVSGQLVANGYVIEIEDRGLGMKPEDLDAANERIADPPEFRITGTARLGLYV
                     VSQLAKRHDIQVVLKASPYGGTTVVVLLPQELVQLDPTPDPHDGGERERLPRRQPAVAT
                     ATRPTTAPPRASAENVRTLPTRPTPVPAPGPAPVPAPGPAPDSRPRPQAAPAPRPEPAP
                     APEPEAETPAEPEQQSVTEFTPGGLPLRVPQANLAPALRDDTPTQPDFEEDDDERSPEE
                     IRAMMGSLQSGTRRGRSQAAKMLEDQQGGDA"
     misc_feature    9676..9689
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(9831..9844)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.75"
                     /tool="antismash"
     misc_feature    complement(9895..9915)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.15"
                     /tool="antismash"
     gene            10001..10891
                     /locus_tag="BKM31_RS02780"
                     /old_locus_tag="BKM31_02755"
     CDS             10001..10891
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="BKM31_RS02780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02755"
                     /product="hypothetical protein"
                     /protein_id="WP_080036638.1"
                     /sec_met_domain="T1TS (E-value: 7.1e-25, bitscore: 87.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDFLRPYPALFADGDSSASRLAFSCLAAAATFPRAPRRRIADLG
                     ALSTILFGVDDITDRVAQDGTDQDAGELFRELSSVLSGAPPEGGGTRPVEQAVHAWHAW
                     CERFRTYEGAAAYLPELARQLERTGEAMAREHVWATGGRPWPSYEEYLPNALVTFLYHT
                     WWSAALAMCDPEPAGTGAWRALEPVTDLGAACLRLANDVRTFERERGEGKPNAVLILER
                     TGMSTEAAVERVSAHIRELNAEFAAAIAGLPAELAWAADGQYRCVTFSGGWYMARDTHA
                     YTVRDLAADAEAHRR"
     gene            complement(10888..12408)
                     /locus_tag="BKM31_RS02785"
                     /old_locus_tag="BKM31_02760"
     CDS             complement(10888..12408)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654755.1"
                     /locus_tag="BKM31_RS02785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02760"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_230465967.1"
                     /sec_met_domain="T2TS (E-value: 7.7e-86, bitscore: 288.2,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIGEALDLTAQADELVTSLMLRPWGQVSPSVYETGRLVSLAPWL
                     TGHQERIDYLIRTQRPDGSWGAPDGYGVVPTLSATEGLLAALTRRDQEAGRDRLADAAQ
                     RGLRVLTTWLSGPLDLPDMPAIEHIVPSLVARINEHVEGSPVPLPPAMSYDALHLVRSR
                     VRSGKEVPEKLLHALEIAADAAAQAPGIRPTPIGSVGASPAATAAWLGERAEPDAHEPA
                     RGHLEAVVRLFGGPVPVGLPITVFERGWVLSWLLRAGVTVDVPPEMVADIRAAIGPSGT
                     PAGPGLPADADTTSVALYALALLGAPHEPESLWAFRSGTHFATWPGEQGVSVSVNAHVL
                     DAFGEYVRRRPAAAPRYAPAIGELAAWIRERQRPDGSWTDRWHASPYYATASCALALDA
                     FGGEASRESVRAAAEWVLATQRPDGSWGRWEGTAEESAYAIQTLLLTGGSAEPRRLRAA
                     ERGQPHLVDPAGGEHPPLWHDKDLYVPRAVARAAVIASSHLVRQALAG"
     misc_feature    complement(11713..11715)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12405..13712)
                     /locus_tag="BKM31_RS02790"
                     /old_locus_tag="BKM31_02765"
     CDS             complement(12405..13712)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="BKM31_RS02790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02765"
                     /product="cytochrome P450"
                     /protein_id="WP_186404283.1"
                     /sec_met_domain="p450 (E-value: 7e-69, bitscore: 232.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDPVTELARMGTDASGQIVRLHLGPFRPYLVSHPDHVQQVLKTD
                     WTNFVREGVFWRPLQRLIGHESILGEGEGWASARKILQPLFTARYVASLAEDMADIIAE
                     RVAGLGDLTRGDSPIDVEHHMTSIVNQAVIKVLFGGRISPETAESLAPEFATCATSIGF
                     RMLLPFASYSIRLPGDRAFLRAAKKIDEIVYPLIERAKRENNDGKEVVSALLTARLEKE
                     GRADLRQVRDDLVNIYGAASETTAMSLIWLWQVLHDHPDVNARLQEEIDRVVGGGPVRP
                     SHVAEMPYLRAVLQELLRVYPNAWVVPRQTVADTVIGGVPVKAGSQVLISPYTTHRLEE
                     FWPRPLEFDPGRWTDDTGERRHRYAFIPFGLGPHVCLGQHLFYIEASLVIANLMSRYRP
                     VVANPQKLRPVPGGATLRPKQKLFLHLQPIERNRAA"
     misc_feature    complement(13810..13825)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    complement(13935..13949)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     misc_feature    complement(13987..14001)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.68"
                     /tool="antismash"
     misc_feature    13992..14007
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    complement(14033..14046)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.32"
                     /tool="antismash"
     misc_feature    14087..14107
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     gene            14107..15084
                     /locus_tag="BKM31_RS02795"
                     /old_locus_tag="BKM31_02770"
     CDS             14107..15084
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546445.1"
                     /locus_tag="BKM31_RS02795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02770"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_080036640.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-56, bitscore:
                     191.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARCRGLLEPALRQAVSVLHPWGARMAAFALGWSDTDGGPSAGDG
                     GKGVRPAITMLSAEAVGGTAESALPGAVAVELVHAFSLAHDDIIDRDELRRHRAALWKA
                     YGVGPALLTGDALLALAVTQLAGRPEAMPYLSAALIELVQGQTADMAFENRPWRGPDAV
                     TIDEYAEMAAGKTGGLLGAATAAGVALGGAPELADRMWAAGRDLGIAFQIVDDMLGIWG
                     DPRLTGKPVHSDLRRDKKTLPVLAALASDGPAARELAAVLASGTGDEESVRHAAHLVEE
                     AGGRERARALADRYLSSALGVLDACLPDAAELRALCHSLVDRVN"
     gene            complement(15119..16084)
                     /locus_tag="BKM31_RS02800"
                     /old_locus_tag="BKM31_02775"
     CDS             complement(15119..16084)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546443.1"
                     /locus_tag="BKM31_RS02800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02775"
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="WP_080036641.1"
                     /transl_table=11
                     /translation="MRPRLLGCLVGAVIAAGLCLAVLVVMVVLRPGGRETPRPQPSPSA
                     TEIVAERRLDERRMELTIRSRALDATTKVRLLLPRGWESRTGWPVLWLLHGGLDDETSW
                     TAKTDVEALTRDTGVLVVMPDGGKCGSYSDWWNGGEGGPPRWETYHLKELRPLLEARYR
                     AGGRQAIAGYSMGGQGAMLYAAKGHFEAAASFSGALHILSPGVPQAVMAGTALGCFGTD
                     WKRIWGDPEEQREVWRAHNPYDLAGELKGVRLYVAAGEGDLVEDLANRAARAFAGRLEE
                     LGIPVRTHFYRGGHNHTFWQRELHRAFPLLMSAIGAKTVR"
     misc_feature    complement(16053..16068)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(16070..16072)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16121..17050
                     /locus_tag="BKM31_RS02805"
                     /old_locus_tag="BKM31_02780"
     CDS             16121..17050
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546444.1"
                     /locus_tag="BKM31_RS02805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02780"
                     /product="aldo/keto reductase"
                     /protein_id="WP_080036642.1"
                     /transl_table=11
                     /translation="MRSIGTTDLSVFPIALGTNVFGWTADKETSFAILDAYVDGGGNFL
                     DTADVYPYWATGESTSETIIGEWLASRRNRDSIVLATKVGMLEGLRGLAPATIRTAVED
                     SLRRLRTDYIDLYWAHVDDHDTPLVESLAAFDALIQEGKVRHIGASNYSAPRLTEALKT
                     SDSEGLARYVALQQPYNLVERDYEGELRDVVAREGLSSVPYFGLARGFLTGKYAPGAHV
                     DSPRAGKAAEYLDTAHGPRTVEALGRLAEERGVAPASVALAWLAAQPTVTAPISSARDL
                     AQLGPLMEAAALSLSAEELSILDTASRP"
     gene            complement(<17293..17631)
                     /locus_tag="BKM31_RS02810"
                     /old_locus_tag="BKM31_02785"
                     /pseudo=""
     CDS             complement(<17293..17631)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013156307.1"
                     /locus_tag="BKM31_RS02810"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02785"
                     /product="STAS domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQDIVIEVVGPVGDCAVLKVAGEVDVFTAPKLREQIIDLAAKGTV
                     HVIADLSAVQFLDSTGLGVLVGGLKRLRTQDGTLSLVMTTDRISRIFKITGLTAVFASH
                     SSVHDAITA"
     misc_feature    complement(17679..17697)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.26"
                     /tool="antismash"
     misc_feature    17725..17739
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.52"
                     /tool="antismash"
     gene            17805..18239
                     /locus_tag="BKM31_RS02815"
                     /old_locus_tag="BKM31_02790"
     CDS             17805..18239
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="BKM31_RS02815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02790"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_168007643.1"
                     /transl_table=11
                     /translation="MRVEEAIGRQIARLRAERRMSLTELGEALGRYLDRPWSRQAVHQA
                     ERGQRSFTAAELTALALVLDTSVPVLFRAEEDRIELPGGAVSPEDYRGILLNREPDMPL
                     DGVEELIVALHDIGEVLARPALARLARIGRVADQVAGPDR"
     gene            complement(18957..19208)
                     /locus_tag="BKM31_RS02820"
                     /old_locus_tag="BKM31_02795"
     CDS             complement(18957..19208)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS02820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_02795"
                     /product="hypothetical protein"
                     /protein_id="WP_155126435.1"
                     /transl_table=11
                     /translation="MRGHRVRGGGLLGEPRLGEPRLGEPRLGEPRLGEPRLGEPRLGEP
                     RLGERRLGAWGAGASGGWGGPGGRCKRGRRAPIVMRGA"
     gene            complement(19358..20872)
                     /locus_tag="BKM31_RS02825"
                     /old_locus_tag="BKM31_02800"
     CDS             complement(19358..20872)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653340.1"
                     /locus_tag="BKM31_RS02825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02800"
                     /product="MFS transporter"
                     /protein_id="WP_080036646.1"
                     /transl_table=11
                     /translation="MTITTPAVPTRRRWAGLAVLSASVLLVVMDMTVLNVALPAISADL
                     RPESIELLWMVDAYALVLSGLLVTVSALGDRWGRKRMLMTGFAVFGLASTTVLAADSPL
                     EVIAVRALLGVGGAMIMPSTLSMIRNLFTDPAERAKALGVWSAMAAVGAALGPLVAGVL
                     LEHFSWHAAFLVNVPVMVLAIAFGLFLLPESKNPRPGRWDALATLLSMAGMVALVYAIK
                     NFGKYGLTSPGALVASVVAVVALGWFAVRCLRRPDPLLELRLFRSAPFSAGVVTALITS
                     IAMASVLLLLAQWMQLVQGYGPLEAGVRLLPAALAAVIASPLAPSLAARIGARTVLAGG
                     LALTGVAFLLLFVVPGPLGYWTVAVALTLVGLGNGSLAIASATIMSGSPPAKSGSAAAI
                     EETSYELGGALGVAVLGSVAAAAYRSEVTYSGPGAGVVRESLGGALDVAKELGAAGGRL
                     AEQATAAFTNSLTLTSGVAALLLAVGALVVWWLTPRHLDLSAADHH"
     gene            complement(20869..21444)
                     /locus_tag="BKM31_RS02830"
                     /old_locus_tag="BKM31_02805"
     CDS             complement(20869..21444)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892769.1"
                     /locus_tag="BKM31_RS02830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02805"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_080046448.1"
                     /transl_table=11
                     /translation="MAATRDQIMKAAIQHLNESPAASMAQLAEAVGISRATLHRHFSSR
                     DDLMLALAHRAHDQWEDLQTSSGMVAATASQDRAALERALKALLEGLIEVADEYGFGLT
                     DDRLATHPELKRRADELEEREVVFYAAAQRAGLLRADLPARWISNTVFGLLVAVRESLR
                     NGDVARRDVARLLLDTFLHGAAPEKERA"
     misc_feature    21459..21468
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.0"
                     /tool="antismash"
     misc_feature    21460..21473
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.75"
                     /tool="antismash"
     misc_feature    complement(21461..21474)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.48"
                     /tool="antismash"
     misc_feature    21461..21475
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.95"
                     /tool="antismash"
     gene            21626..22456
                     /locus_tag="BKM31_RS59275"
                     /old_locus_tag="BKM31_02810"
     CDS             21626..22456
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="BKM31_RS59275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02810"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_186404282.1"
                     /transl_table=11
                     /translation="MSGDAHTRNLNDAHPRILNDRRTRILDDGHPGIPDDGRTRILNDG
                     HPGIPDDGRTRIPDDRHPGIPDDGRTRILNDGRPGIPDDGRTRILNEGHPGILNDVRTR
                     ILDAAEELFACGGYAATPTTVIAKLAKVPGDLISQYFPRKIDVLVALVDERTHVEENDQ
                     VDAVPGDLAGTLSRLARVLPLRASPAMRRILSREADTHGSVKERLGRLNGELVRRARFA
                     LGLALPGARGDAARLEVAAATFAAILIYQENLCQLTGHQIDPDAVAELIAHSLV"
     cand_cluster    21694..44255
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    21694..44255
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[31693:34255](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      31694..34255
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     gene            complement(22394..24499)
                     /locus_tag="BKM31_RS61915"
                     /old_locus_tag="BKM31_02815"
     CDS             complement(22394..24499)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014998.4"
                     /locus_tag="BKM31_RS61915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02815"
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_230465968.1"
                     /transl_table=11
                     /translation="MRQLTALDAQFLNVETPTTAAHVAGLAILDPADGAVTRSALAELL
                     LDRIHLSPALSLRLAEVPLRLDHPYWAADPDFDLDHHLFETTLPEPGDHWQLADTVAQL
                     HARRLDRAHPLWEMHLIHGLNDGLVAVYTKVHHAAIDGISGAETLATLLDLTPDGHLTP
                     RRHSTPVSESAEAVSGGGANNGESGPARGRDGGAAGGEGGAVGEGGACAGVAVRGGRAG
                     SARAGSSRSRQAARDARPDGTGLHDAHPDNARPNGAHPNNASPNDAHPNGASPNGACLN
                     NASPDGGSLNDARPNDARLSGAHPDDALPNGAHPNGASPNDVHPTGAHPNGASPNDTSP
                     NDTSPNDTSPNGANPDDVSLIGASPDDTGQVDSGVGSVGDEAPGLVGMLAGAVLRSATQ
                     PVRAVRSVVRAAGDLDVIPVVGGLPGARLVARAARMVGREGQRRPELPSLAAPRTPFNG
                     PISARRHLSFGSVSLKDVKKVAKANGVSVNDVVMTLCTSALRSWLCERDALPEAPLVVG
                     VPVAVRKAQAKDLVGNQISAMVAPVPTHLSDPKERLREVGAAMGRAKRRFAVAPATWLS
                     ELCSILPTPVTSLATPAIFRLAGMAFPPINLIISNVPGPQFPLYLCGGRILSYYPLSVL
                     TDLSGGLNITCFSYDGMLDFGIVACPERVDDVWGLLVHLRTALDELLDERVGDEFRDGV
                     GVDLVAG"
     gene            complement(24642..25688)
                     /locus_tag="BKM31_RS02850"
                     /old_locus_tag="BKM31_02820"
     CDS             complement(24642..25688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546440.1"
                     /locus_tag="BKM31_RS02850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02820"
                     /product="sulfite oxidase"
                     /protein_id="WP_080036647.1"
                     /transl_table=11
                     /translation="MKQATAAIVKPLPDHLFKVHGNSAEMRWEAMAGLGYHTPNDRFFV
                     RNHTFTPLIDVTTWRLGIHGAGVRCPRAFSYEELRAMPSRTYDVAIECAGNGRRFYRTQ
                     QHDGAPGTQWGLGAIGVARWRGVPLKYLLDQAGVRPEAVDVLPVGLDAPFEEHGHVRRP
                     LPIGKAMDDVLVAYEMNGVPLPPDHGFPARLVVPGWVGIASIKWLGDIEVSTEPLFTPW
                     NTVFYPDVTTQPVKSAFELAWNARLPVAGPHILHGRSWSGRGRIVRVEVSFDGGLTWRT
                     AEHHGQHLVKAWLPWHVAWAPRRTGTRLLMARATDETGATQPLTTPRHPFGYHFDAVVQ
                     HPIHVVNG"
     gene            complement(25972..26709)
                     /locus_tag="BKM31_RS02855"
                     /old_locus_tag="BKM31_02825"
     CDS             complement(25972..26709)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS02855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_02825"
                     /product="hypothetical protein"
                     /protein_id="WP_080036648.1"
                     /transl_table=11
                     /translation="MHSARKKPRTLLARVFAVLAALLVAALAGVALAYPSLAATTCPGC
                     YGLTELEDSVYTEDGLSEAQQAQVKQTIAEARHRVTAFYGSQTSTPTLLVCVTEGCYER
                     IGGGKERGIAVLNRAVMLSPRGLDPVIASHEMSHVELHTRLTSGAEVPQWFDEGLAVVV
                     SDDPRYLAPKTTEDRCLASPSGPLPATLDEWLSTASKDANTYAKSACQVSRWLHANGDR
                     TGLLSLIEHLNTGTPFASLVSPA"
     misc_feature    complement(26062..26064)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            27045..27347
                     /locus_tag="BKM31_RS02860"
                     /old_locus_tag="BKM31_02830"
     CDS             27045..27347
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKM31_RS02860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKM31_02830"
                     /product="hypothetical protein"
                     /protein_id="WP_080036649.1"
                     /transl_table=11
                     /translation="MPGLLLGVALAVIPPAPVGADSVSRSPTCRYVNQTHKPAPVRLGP
                     GKKYRKTAELPPSGEPVKATCAARGRGPEHWVRIKEGEQKGRWVWRNRLQVWNGE"
     gene            complement(27362..29041)
                     /gene="polX"
                     /locus_tag="BKM31_RS02865"
                     /old_locus_tag="BKM31_02835"
     CDS             complement(27362..29041)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="polX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546438.1"
                     /locus_tag="BKM31_RS02865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02835"
                     /product="DNA polymerase/3'-5' exonuclease PolX"
                     /protein_id="WP_080036650.1"
                     /transl_table=11
                     /translation="MRANEEAAAALQEYAELFALSGGDAFRVRSYQKAAKAIAGFPEDI
                     SVVDVRSVPGVGEAIAKKMEEFLERGSFRQLDDLRGRVPDGVRRLTRVPSLGPKTAIML
                     FEDFGIDSTTALSEAITSGRLDGVKGLGPKTLANLLKGIEQLEQSGRRVHIGVAMSLAE
                     QVMASLKAERIAYAGSLRRMRDTIGDIDILAVAPDSIMEDFRAQPYVADVIAAGDKKTS
                     IRTTSGIQVDLRVVPAGSWGAAMQYFTGSKEHNVAIREMAVKKGWKLSEYGLFEGERVI
                     AAESEEDIYDALGMQYVPPPMREDGGEVKAALAGELPVLVELADLKGDLHTHTDLTDGI
                     ASLEDMVAAGHARGYAYYAVTDHAPDLAMQRMTLDKALEQRGRVAELQAKYPDMRILHG
                     SELNIAPDGSVDWPAEILREFDVCVASVHSHFTQSRDEMTRRFIAACENPYVDIIGHPT
                     TRKIGKREPVDADWDAVFRAAARTGTAMEIDSYPDRSDLPSDLVRLAKHHGVKFSIDSD
                     SHAIPHLAHQRFGVGIAQRAWLTSDDVINTWPLERLLAFLGR"
     gene            complement(29193..30161)
                     /locus_tag="BKM31_RS02870"
                     /old_locus_tag="BKM31_02840"
     CDS             complement(29193..30161)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892748.1"
                     /locus_tag="BKM31_RS02870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02840"
                     /product="aldo/keto reductase"
                     /protein_id="WP_080046451.1"
                     /transl_table=11
                     /translation="MEYTRLGNSGLKVSRLCLGMMSYGDPAKQQWALAQDEAEPLIRRA
                     ADAGVTFFDTADVYSAGASEVVTGAALRAIFPRREDYVLATKVFFPMGKGRNDGGLSRK
                     HIMDAIDASLTRLGTDYVDLYQIHRWDDETPIEETMEALHDVVRAGKARYIGASSMWAW
                     QFAKAQHVAESRGWTKFVSMQNHYNLLYREEEREMLPLCADQGVGVIPWSPLARGVLAR
                     AGSTATTARTGSDERIDYLYDPENDKLVIDRVAQVAADRGLPAAQVALAWVLHRSEITA
                     PIVGATKPRHVDDAVAAVSVRLSAEEAAFLEEPYRPREVRF"
     gene            30433..31557
                     /locus_tag="BKM31_RS02875"
                     /old_locus_tag="BKM31_02845"
     CDS             30433..31557
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="BKM31_RS02875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02845"
                     /product="histidine kinase"
                     /protein_id="WP_080036651.1"
                     /transl_table=11
                     /translation="MTFHGRRAKLRDLRARLNGPSWVGGLGLAAGIAGLCVPVLAGLAA
                     SKALAGGAVALVVLLGLHVAFITESPVRRAGAWWIVAVQAWLTYLPLTMFGAAWTPVCG
                     LLAGAVLVMAARIRSVVLVLLALACGPVVLAAPDRTMIDPLWALAAPLTGLAEYAVITL
                     TQRARRLGEARTEVMRRAVAMERRRFTRDLHDLVGHRLTVLVLKVQLLERLVAEGDEKA
                     RVEVSETLELLRNLSADVRAVAHGLRSSSLAAELGSARSLLESARVRCQIRVSCRDLPG
                     AVEEALTHALREGVTNVLRHAEARQCSVHLLERDHMVRLTIRNDGVRPPRRPGDAGQGL
                     LNLADRVSALGGWLEATSSRTGQFTFSVYVPRKK"
     misc_feature    31267..31269
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(31686..31701)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            31694..34255
                     /gene="lanKC"
                     /locus_tag="BKM31_RS02880"
                     /old_locus_tag="BKM31_02850"
     CDS             31694..34255
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017559021.1"
                     /locus_tag="BKM31_RS02880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02850"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_080036652.1"
                     /sec_met_domain="micKC (E-value: 6.9e-245, bitscore: 814.4,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2e-13, bitscore: 49.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 2e-06, bitscore: 27.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.4e-09, bitscore:
                     36.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKYELYCLVDPCFYDNLEHSTATDADFPILRRPLPAGWSSARTD
                     TWCYFAPDSDTPLPAQGWKIHVSARVEDAEKAIETVWDYCMPRGVAFKFLRGLPVLVMV
                     NSKAASRASSGKLVTLYPRDEAQLELVLKELDELLRDVRGPYILSDLRYNEGPLFVRYG
                     GFAERHCLSLTGERVLALEDGDGRLVPDVRGATFSVPPWTTLPAFLEPQLAARNAVTTT
                     GLPYTIESVLHFSNGGGVYLGRDKRTGERVVLKEARPHAGLDAAGRDAVARIEHERDIL
                     ERLSGLPAAPALRGYFTLGEHHFLVQEFVDGTPLQRRLVHRYPLTRATCTERDLAEYTE
                     WAVRTLEEVTRAVGSLHERGVVFGDLHPDNILLTDEGRVALIDYEVATLAEDRARAALA
                     HPAFAAPADRQGVDVDRYALACLRLGLFAPQCTIMLPLHRPKVVHLGEIVKETFPVPAS
                     MIDGAVATIAGGERDTAAVPMPGVASWPELRNAMATAITAAATPGRDDRLFPGDVAQFQ
                     PGGGLNLAHGAAGVLFALHSAGLGPYPEYESWLRERARRPVQGSGLGLYDGLHGIAYVL
                     DLLGHHEDAHDLVEICLREKWDRLESALISGLSGIGLNLLHFGHTDLALRAVDICAGRL
                     DTPVPEISGGTNPRAGLMHGSSGPALLFLRAYEQTGDPALLDLAATALRQDLRRCRHSE
                     DGSLQVNQGWRLLPYLDEGSAGIALVLERYLRYRHDEAFGTALAELRLAGRAGFFVQAG
                     LFTGRAGIIAAGAGDVPELVKGLRWHALPYAGGLAFPGDQLLRLSMDFATGTAGVLFAL
                     ASALGDGPCHLPFLEAAPERPLPDDTTEGGVRHGSSRPAGS"
     misc_feature    32108..32110
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            34227..34358
                     /locus_tag="BKM31_RS59280"
     CDS             34227..34358
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653864.1"
                     /locus_tag="BKM31_RS59280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_103955008.1"
                     /transl_table=11
                     /translation="MVLLDLQGLEAPAASDVASGGSTLTVLSCHSGKPSNLSVALCH"
     CDS_motif       34227..34283
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVLLDLQGLEAPAASDVAS"
                     /locus_tag="BKM31_RS59280_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       34284..34358
                     /prepeptide="core"
                     /locus_tag="BKM31_RS59280_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="11.30"
                     /molecular_weight="2242.5"
                     /monoisotopic_mass="2241.2"
                     /core_sequence="GGSTLTVLSCHSGKPSNLSVALCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLLDLQGLEAPAASDVAS"
                     /leader_location="[34226:34283](+)"
                     /alternative_weights="2260.6"
                     /alternative_weights="2278.6"
                     /alternative_weights="2296.6"
                     /alternative_weights="2314.6"
                     /alternative_weights="2332.6"
     gene            34428..36119
                     /locus_tag="BKM31_RS02885"
                     /old_locus_tag="BKM31_02855"
     CDS             34428..36119
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892885.1"
                     /locus_tag="BKM31_RS02885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02855"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_080036653.1"
                     /transl_table=11
                     /translation="MRAGDRLVAGAVRRSGPWPAVLAGTAVVGAAGELAVPYLIGRTVD
                     TLVTRGPDATHWLALCAAAVAAVMLCESIGVWARGASGAHAAATLRTGVLRHVLGTGSA
                     ATRRFPEGELVTRAGLNAEEVGRAPETVTSALALLVPTAGALVALTLIAPVLTLTLGAG
                     IVVILLVLRAFLRATTTISGGYQEVQGEIAARLVEALGGARTIAAAGTAGRESRRVLAP
                     LPRLRAHGMGLWRANASAAVRSGLVVPLLEIAVLAAGGFMLAAGDLTVGELYSAARYAV
                     LGASLSTALGHIGGLARARAAAGRVAEVFDLPPVRYGSRTLPPGPGTLRFRDVAVNGLT
                     VGDLTLPGGSVTAVVGRSGSGKSLLAALAGRLAEPERGTVLLDGVPLGELAEAELRRAI
                     GYAFERPALVGETIGDAIAPEPEPVPEFAEPPGRRVVEAARAACADVFVRRLPLGYATP
                     LRDAPMSGGERQRIGLARAFAQGERLLVLDDATSSLDTVTERQVGRALTSDPLGRTRLV
                     AAHRPATAARADQVVWLDGGTVRACGPHHVLWRDPAYRAVFQGAEP"
     gene            36145..37938
                     /locus_tag="BKM31_RS02890"
                     /old_locus_tag="BKM31_02860"
     CDS             36145..37938
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075999.1"
                     /locus_tag="BKM31_RS02890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02860"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_080036654.1"
                     /transl_table=11
                     /translation="MNPQDTGGRVVHPLAHALRREPRQLVRLGLWSVVEAAPAFLIGQA
                     VARAIEDGFAAAAPMIGLAWLAALGVAWLAGAVAARQVVLAVAAVAEPFRDDLLTRVVA
                     GALRTGTGRDSAAVARAGLQVELARDAFAAVVTTVRGFVFTVISVVLGLLTLAPETLLL
                     VMPPFLAGLCLFLASLPALARRQRAYLVADERLAEAMTEMAGGLRDIEACGLRDSVAAR
                     LERRVGAQAAAARRLARVSAVRTAALAAGGWLPVVLVLAGTPWLMERGVGAGVIVGTLA
                     YVTQSLAPALGGLVQGLGVSGVRLAVSLGRILAMAPPPALAPPLIRPATTEIRLDAVTF
                     AYGPHSAPVVVGLDLVVPEGDHLAIVGPSGAGKSTLASLISGLLRPGKGEVLVGGVPAD
                     RLDPAARVLIPQEAYVFRGTLRENLLYHARTDTGPDTGPAEAGPADAALTDAALTDPTL
                     TDPTLTDAALAEAVAAVGADRLVDELGGYDAPVEPGALSAGQRQLVALARAYLAPAAVV
                     ILDEATCHLDPAAEAVAEAAFARRGGTLIVIAHRLTSALRARRILLMDGTRITLGTHEE
                     LVRTSPLYADLAGHWHPEPVS"
     gene            37935..39917
                     /locus_tag="BKM31_RS02895"
                     /old_locus_tag="BKM31_02865"
     CDS             37935..39917
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851705.1"
                     /locus_tag="BKM31_RS02895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02865"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_080036655.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.2e-57, bitscore:
                     194.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFPDNYPPAERLPLTDRRHGHEIDDPYRWLEDPVDPRTRAWLAA
                     QDRLWQDAAARLPRRERFLARLTEARETGLVTPPVWRGGRRFHLRQSPDQEHPVLCCDD
                     RVVLDPMELDPSGLTTLDDWQPDLEGRRLAYQTSRSGDEKACLYVRDLDTGAIVDGPIG
                     GCRYSAVAWLPGGEAFYYVRFQQGVFLHRIGSAEADVPVFTRGAISYGVQISPDGRWLT
                     ISAGTASGNGLWLADLAGEDPAPRPVQDGSHARTAGAVARDGRLYLLTDRDAPRRRLCV
                     ADPEAPAAWRELIPEDGEAVLGAFTLLDGDRLLVSRTRHAVGEIAVHDARTGERIGMVP
                     LPGNGSIASLTSRPEGGPEAWFAYTDAVTPAEIWRYDARTDATTRWSAAPGRGTPPEVR
                     SHHVEYASADGTVIRMIVVARPSAGGPRPAILSGYGGFGIPLMPGYAADSLAWVEAGGV
                     LAIANLRGGGEEGEGWHRDGMRERKQNVFDDFVAAAEKLIADGWTTPEQLGIWGESNGG
                     LLVGAALTHRPDLFAAAVCSAGLLDMARYHLSGLGPSWTGEYGDPDDPEQLGWLLAYSP
                     YHHVRKGVDYPATLFTVAAADTRVDPMHARKMCAALQWASGGDRPVLLRYEPDVGHGAR
                     AVSRSVALAADVLAFLAEHTGLDLP"
     gene            complement(39918..40523)
                     /locus_tag="BKM31_RS02900"
                     /old_locus_tag="BKM31_02870"
     CDS             complement(39918..40523)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017579212.1"
                     /locus_tag="BKM31_RS02900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02870"
                     /product="response regulator transcription factor"
                     /protein_id="WP_080046452.1"
                     /transl_table=11
                     /translation="MIRTLLAEDMHLVRGALVALLAYEEDIEVVAEVERGDRILAAARA
                     CRPDVAVIDIALPGQDGLSAAGELHEKLPECGVLILTGVGTPGLLKKALDVHVRGFMAK
                     DAPPGRLADGIRRVAEGERVIDSELAIAAMRPAEAPLTPRELDVIGAAADGASVGEIAA
                     SLYLAEGTVRNYLSRTTAKLGARSRIDAIRIARESGWI"
     misc_feature    complement(40305..40307)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(40353..40355)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(40594..40608)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    complement(40595..40610)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.23"
                     /tool="antismash"
     misc_feature    40614..40630
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.13"
                     /tool="antismash"
     gene            40695..41198
                     /locus_tag="BKM31_RS02905"
                     /old_locus_tag="BKM31_02875"
     CDS             40695..41198
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546436.1"
                     /locus_tag="BKM31_RS02905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02875"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_080046453.1"
                     /transl_table=11
                     /translation="MKPRVRPLPPEHWDEFTKAHPYNVFATLARHPALYRGWRDFHGAL
                     QDGTLPARDRELAILRTAHHCDSAYEWARHARLALDAGLTRQEVELVRRPDALWSVEDQ
                     LVLQVADDLYYAGDLTDATWAALCDRYDEAGRIELVMLVAHHGMLALVLRTFRVRPEPE
                     ITEE"
     gene            complement(41185..42213)
                     /locus_tag="BKM31_RS02910"
                     /old_locus_tag="BKM31_02880"
     CDS             complement(41185..42213)
                     /NRPS_PKS="Domain: PKS_ER (15-264). E-value: 2.8e-20.
                     Score: 64.6. Matches aSDomain:
                     nrpspksdomains_BKM31_RS02910_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546435.1"
                     /locus_tag="BKM31_RS02910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02880"
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_080036656.1"
                     /sec_met_domain="ADH_N (E-value: 3.7e-29, bitscore: 100.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.8e-30, bitscore:
                     103.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVAFDIFGGELDVRELPDPSPAPHGAVIRVEATGLCRSDWHGW
                     QGHDPDIKVLPHVPGHELAGVVEAVGSDVRGWLPGARVTVPFICACGSCAACATGEQQV
                     CERQTQPGFTHWGSFAEYVAIDHADVNLIAVPEDMAYATAAGLGCRFATAFRAVVQVGE
                     VRPGEWVAVHGCGGVGLSAVMIATAAGARVVAVDISGDALHLAELAGATHFVNGSDGDA
                     AAQVRELTRGGAHVSIDALGSPATCAASVESLRRRGRHVQVGLLPGGATPVPMGRVIAH
                     ELRLLGSHGMAAHAYPPMLEMIRAGILHPDQLVTRTIGLADAGKALASIGSVPGVTMIT
                     PR"
     aSDomain        complement(41422..42168)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS02910_PKS_ER.1"
                     /evalue="2.80E-20"
                     /label="BKM31_RS02910_PKS_ER.1"
                     /locus_tag="BKM31_RS02910"
                     /protein_end="264"
                     /protein_start="15"
                     /score="64.6"
                     /tool="antismash"
                     /translation="RELPDPSPAPHGAVIRVEATGLCRSDWHGWQGHDPDIKVLPHVPG
                     HELAGVVEAVGSDVRGWLPGARVTVPFICACGSCAACATGEQQVCERQTQPGFTHWGSF
                     AEYVAIDHADVNLIAVPEDMAYATAAGLGCRFATAFRAVVQVGEVRPGEWVAVHGCGGV
                     GLSAVMIATAAGARVVAVDISGDALHLAELAGATHFVNGSDGDAAAQVRELTRGGAHVS
                     IDALGSPATCAASVESLRRRGRHVQVG"
     CDS_motif       complement(41656..41706)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS02910_0002"
                     /evalue="3.80E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="BKM31_RS02910"
                     /protein_end="186"
                     /protein_start="169"
                     /score="13.2"
                     /tool="antismash"
                     /translation="VAVHGCGGVGLSAVMIA"
     CDS_motif       complement(42001..42036)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS02910_0001"
                     /evalue="5.90E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="BKM31_RS02910"
                     /protein_end="71"
                     /protein_start="59"
                     /score="9.7"
                     /tool="antismash"
                     /translation="GHELAGVVEAVG"
     gene            complement(42215..43045)
                     /locus_tag="BKM31_RS02915"
                     /old_locus_tag="BKM31_02885"
     CDS             complement(42215..43045)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019632891.1"
                     /locus_tag="BKM31_RS02915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02885"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_080036657.1"
                     /transl_table=11
                     /translation="MNRDELAEFLRVRRARVTPADVGLPAGGTRRTPGLRRQEVAQLAG
                     MSIDYYIRLEQGRGPHPSRQVLNAVARALMLGQDERAHLFHLAGQPMDPPRIREDVPQS
                     MLHLIAFLDDVPAYVLDARYDLRAWNPMATTIMGNLDCLAPDQRNVLRWIFMSPDIRLH
                     FDDEEKGAFARASVADLRAAAGRYPGDRRIQALVAELLALSPEFAELWGRHEVQVRREQ
                     RKRIHHPVVGTIDTICQVMPVPDRDDLRLVLYTTEPGSPSHRALRELRQHTLSS"
     gene            43149..43859
                     /locus_tag="BKM31_RS02920"
                     /old_locus_tag="BKM31_02890"
     CDS             43149..43859
                     /NRPS_PKS="Domain: PKS_KR (4-137). E-value: 9.1e-09. Score:
                     27.4. Matches aSDomain:
                     nrpspksdomains_BKM31_RS02920_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019632890.1"
                     /locus_tag="BKM31_RS02920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKM31_02890"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_080036658.1"
                     /transl_table=11
                     /translation="MTNIALITGANKGIGYEIARLLAGQGVTTIVGARDEERGRAAAER
                     LGQPYVRLDVTDEESVAAAAKWIDGEYGRLDILVNNAGITGDTAAYLPSAATAAHLREV
                     YETNVFGVVTVTNAMLPLLRRSPAGRIVNMSSELGSLAMAADPDSPYADVNILAYNSSK
                     SALNMVTVSYAKELKDTPIKVNAANPGYCATDLNQHQGFRTAEQGAAIAVRLATLDESG
                     PSGAFLEDAGPVRW"
     aSDomain        43161..43559
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKM31_RS02920_PKS_KR.1"
                     /evalue="9.10E-09"
                     /label="BKM31_RS02920_PKS_KR.1"
                     /locus_tag="BKM31_RS02920"
                     /protein_end="137"
                     /protein_start="4"
                     /score="27.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ALITGANKGIGYEIARLLAGQGVTTIVGARDEERGRAAAERLGQP
                     YVRLDVTDEESVAAAAKWIDGEYGRLDILVNNAGITGDTAAYLPSAATAAHLREVYETN
                     VFGVVTVTNAMLPLLRRSPAGRIVNMSSE"
     CDS_motif       43164..43241
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKM31_RS02920_0001"
                     /evalue="7.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="BKM31_RS02920"
                     /protein_end="31"
                     /protein_start="5"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LITGANKGIGYEIARLLAGQGVTTIV"
ORIGIN
        1 agcgcggggg tgctgctgct cgcctgcgag caggtgctcg ccctcgcccc ggccgggctg
       61 gaccaggctc tgctgggcga ggcaggcacg ggcggagcgg gcgaggtcag gacgggtgag
      121 gccgcacccg tagggtgacg gccgcgtgct ccgcccaggc cgccaggaac cgctcggggc
      181 cgaggtcgcc gggcgtgtgg ccgatcatga ggcggagcag cgggtagtac gtgagggagg
      241 ccagcagcac ggccgcggtg gcctccggat cggcgcactc gacgttgccc cgctcccgct
      301 gctcctcgat ccaacgggcg ccctgggcgt acacgccggc catcaccccc tgccacatgc
      361 cctcgaacag ctcgccgaac ccgtcgaact cccgcagcat gatccggatc agctcccggt
      421 cctgctcgat cacctcccac acggcccgcg ccatccgctc cagatcggcc cgcgggtcgc
      481 cggtcgcgac ggccgtctcg ccgccccgct ccgcgatccg ctccaggttg cgccgcaccg
      541 ccgcctccag cagcgcccgc ttggacggga agtgcttgta gagcgcgccc gagccggtcg
      601 tcagcccgca cgcggcctgg atgtcggcga ccgaggtggc cgcgtagccg cgcgtgcaga
      661 acaacctgac cgcctcgtcg atgaggcgct gccgggtgac ccccggcgtg gatctcgcca
      721 tggtaagaga gtactctctc actatgcgag tcttcatcgc gggcggcacc ggcgcgctcg
      781 gccgccacgc cgtcccggcg ctggtcgcgg ccggccacga ggtcaccgcg ctggcccgca
      841 cccccgacaa ggccgccgcc ctcgaacggc agggcgcccg gcccgtccgg gtgtcgctgt
      901 tcgaccgggc gggcctggcg tccgccttcg aggggcacga cgccgtgatc aacctggcca
      961 ccgccatccc ctccatgagc cgcttcatga gcaccaaggc cctgcgcgcc aaccaccgcg
     1021 tacgcgcgga gggctccgcc gccgtcgcct ccgccgccct cgacgccggg gtcgcccgcc
     1081 tcgtgcagga gtcggtcagc atgctctacc gcgacggcgg cgaccgctgg ctcgacgagc
     1141 acgctcccgt cgaccactac cccctcacca ggggaaactt cgccgccgaa gccagcgccc
     1201 gccgcttcgc cgacaccggc gggggagcgg ccgtcgtgct gcgcctcggc tggttctacg
     1261 ggccgggcgc cgcgcacagc gagcaactgt tcgcccaggc ccgccaccac gtcgccgtcg
     1321 tcctcggccg tcccggcggc tacgtctcct ccatccacct cgccgacgcc gccaccgccg
     1381 tggtggccgc gctcgcggtg cccggcggca cgtacaacgt cgtggacgac gagccgctga
     1441 ccaagcgggc gtacgcggac gccctcgccc gcgccgccgg tgccgtcccg tgggtgcgcg
     1501 ggcccggccg gctggcctac gctttcggcg accggctcac ctccctcacc cgctcgctcc
     1561 gcgtccgcaa cgcccgcttc cgcacggcca ccggctgggc gccccgctac ccgagcgccc
     1621 gcgagggctg gctcgccact gcccgcaccc tcctgtcctg aaacggcgcg cgccttggct
     1681 cacggggctt ccggtcccgg tgcgcgcacg ttcttgagga agatgagccc gtcggtcttg
     1741 tccagctcgc cggggtcgag ggggaagtag ccgtggttgg ccgcggtgtc cgttcgctgg
     1801 atcagttccg cctcacgcac cgccgtcgtc agtcggcgtg agtcgagcac gtagcgctcg
     1861 cccagcagcg tggccagcat gccctcgatc gtcctcgggt ccgggaggtc gaggccctgg
     1921 tgggggacgg tgccgagggc cgaggccagg aaggcgtacc cggtgccgag gcgggcgctg
     1981 gtgatggcgc ccgcgctcca ccactccagc gtcaggtcgc cgagctgcca ccggctcgcc
     2041 tcccgttgca ggtggcggtt gtgggcgaag acgagcgcgg ggccgtgcgg ggcgatggcc
     2101 tccaggttgt cggccatcat ggcgtcgcgc aggcccagca tgcggacgac gcgttccggc
     2161 gccgggtcgg ccatgatcgt gtggtagcgc agcaggcccg tggcggtgcg ggcgtacaaa
     2221 tgtgcgcgtt cccactcctc ccgggacgtc gcggggatga ggcggggtgc gtgcacggtc
     2281 agcagcggca cgaggtcgtc cgcgagcagg cgcagctcgg cgacgtcggg ggagtggccc
     2341 accgactggg acgggtccag cgcggcggcc tcgttcgtcc accgctcgtc ggggcccagc
     2401 agggccagca gcctgtcgcg ggtgcagggg acggcgacgc cggccgccgt caggtaggcg
     2461 tgcagcgcga cgagggtgtg gcgggggccg gcggcgctca tcatctccag gggcgcgtcg
     2521 aagccgaaga agcgcaggcg gtcgccgtcg gggtggctct cgttccaggc gcgcatccag
     2581 cggatgagct cccgtgtcgc ctcccggtcc cagaagccgt ggctgaagcc cgtacgcatg
     2641 acatcgtcca gcgagcccgc gccggtgcgg acgtactcat cgacgaccag gccggccacg
     2701 cagtcactct cgatcgcgaa cgcgcggtag ccctcgtgct cgaccagctc gcggaagatc
     2761 tcgttgcgca gctcgtgcac cgggcgctcg tcgtgcagcg cctcgcccag cccgagcagg
     2821 cgcgggcggg cgggcagcga gcggagcagc cgggtgacgg cgccggcgcc ctcggcgtcg
     2881 aggtcggcgg cggcctcgcg aatggaggcg gcctcgcgga tggcggcagc cccttccgtt
     2941 ctcttcggtg gcgatgtcgt catgccttct acggtatcgt tgaaggttcc gttgagactt
     3001 tgacatcggt tccggcgctc ggatgctgcg ggaccctcaa cctggtgagg tacgtcatgc
     3061 cccgtgggcg gctgcggccg gtggacctgg cgcgcgagca cggcctgtcc acccaggccg
     3121 tccgcaacta cgaggaggca ggcatcctgc ccgccgccgc gcgcaccgag cacggctacc
     3181 gcacctacac ggcccggcac gcgcaggcgt tgcgggcgtt cctcgccctg gtgccggcgc
     3241 acgggcacgc cacggccacc tcgatcatgc gcgcggcgaa cgagggcgcc acggaggagg
     3301 cgctgcggct catcgacgag agccacgccc agctcctcga agaccggcgc acgctggagg
     3361 cggtggagca ggcgctgcgc tccctggtgc cgccgcccgc gccctcggcg gagccgtcgc
     3421 gcgccccttc acccgcgccc aaggcggagc ccggtgtcac cttcatcggg ccgctggcca
     3481 ggaagctggg catccgtccc gcgacgctgc gcaagtggga gcaggccggg ctggtcgagc
     3541 cgcgccgcga ccccgcgacc ggctaccgcg tctacagcgc cgccgacgtg cgcgacgccc
     3601 agctcgctca ccagctccgc cggggcggct acctgctgga gcagatcgcg ccactgatcc
     3661 ggcaggtacg ggcggcgggc ggcctggcgc cgctggagag cgcgctgcgc gactggcagg
     3721 agcggctgtc ggcccggggc cgggcgatgc tgcggggggc ggcggcgctg cacacgtacc
     3781 tggacgagca ggagtaggcg cacccgcggt tcttgtcggc cccggctggc atgcttgcct
     3841 gccatggaca ccacgcgtta ctggcagctc gtcgaagacg cccgcgccgg cgccaaggac
     3901 gagtgggagg tggccgcccg cctctccgag cggctgtcgg ccctcccgcc cgccgagatc
     3961 atcgccgccc agcaggcttt ctgggatctc atgacggcct cctaccgggc cccgctctgg
     4021 ggagccgcct acatgatcaa cggcggctgt tccgacgacg gtttcgagta cttccgcggc
     4081 tggctggtca cgcagggccg cgaggtgttc gagcaggtcg tggccgaccc cgacagtctc
     4141 gccggcctgc cggtgatcca ggaggcggcg gccgactgga cggagaagca ctgcgaggcg
     4201 atgctgggcg ccgcctacaa cgcctaccgg gcggcgaccg gcgaggagct gccccacggc
     4261 tcctacacga tccgctaccc cgccctcgac cccggctggg gcttcgactt cgaggagcag
     4321 cgtgatgagc tgagccgccg cctgccccgc ctggccgccc tctacggccg ctgagccgtc
     4381 acgcgagggg gaagacctcg gtcggccgcc agtggccgcc ggcgtcccgc accagcagcg
     4441 acacggccgt gacccgcgcc gtcaccggca gctccccggc cacccacgcc tcgtccaccg
     4501 cgccgtcctc acccagggtc aggtgcggca cgatctcgtc gtaccgcccg ccgtacggag
     4561 gcgtccccgg ccaccgcccg gtcaccgcct cggtcagccg cacgaacggc ttggcgggct
     4621 ccggcgcgag gaacaccacc ccgggttccc cggtgaagcg ccggatctcg cggaaggtca
     4681 cgtcgacggc tggataccgc atgaacagcg cccgcagctc ccggcgcacc acgtcgtcga
     4741 tgcggggcgc gggcaggaac ggcgtcagca cggtcacatg agcgggcagg ccgatctccc
     4801 gctgccgcca cgggcggacg agcggctcgg cctccggcac gcccagcacg agcgccgtct
     4861 caccctccct ggaggccgcc ttccgggacg ccgccttccc accggacacg gcgttcctac
     4921 cggacgcggc cttcccatcg gacgccgcct tcccgccgga cgcagtcttc ccaccggagg
     4981 cagtcttccc gccggacgcg gccttcccgg acggtgccgc gcttgaagca ctcatccctt
     5041 cactgtcctc ccgcgcccgc accccgtcga tcccggcgaa agcctctagt ctgcagggcg
     5101 tgcacaattc gctcaccttc accgacctgc tcgacgacgc cgccctgctc tcgctggagc
     5161 accaggtgca cctcgaagag gtcctcggcg gccacagctg gcaggtggac ctccagcagc
     5221 cgcgcttcga cttcgcctgc gtcacccgta cgatcacctg caccgccttc cacctgctcg
     5281 gcagcgccgc ccccggcccg ggcacgtggc tgtgggcgtg ggcgaacccg tcgggtttcc
     5341 ctgaggcggt ggtggccgcg tccgcccggc tgcgcgactt cggcctccag tacggcatcc
     5401 aggagctggc gtcggcggag gtcccgttca gcgccctgcc cggcgcgccg acggaggcgc
     5461 atctggcggc ggggctcctg acggaggcgg ccaaggcggt gacgggccgg tggacctcct
     5521 acaacggcga cgcgggtggc ggcacgcgcg cggcgttcct ggtggagcac ccggacttcc
     5581 ggctgccgcc gcccgagccg gcccgcgtca tgcgcgtcat ccagcaggcg ctcgccggcc
     5641 tgcggctcac cgatcaccgg cgcgccctgc acagctacgc ggtcaagcgg ggcctcggcg
     5701 ccgacttctc cggcgagcag ggcaggatca cggggccggg tttcgaggcg gtcgtggagt
     5761 tcgacgggta cggccgggtg gccggcatca aggccggcct gtccgcaccg cacggcggct
     5821 gaccggcatc acggccgctg ccccgtgaga acgaacgcgc ccgccccggt gctgcaggcg
     5881 gggcgggcgc aggggggcgg tcagctgccg accggctcgg cacgcaggcg ggccgagtgc
     5941 ttgacgagcg tgatcaggac ctcccggctg gagtcccgct tgcgggcgtc gcacatgatg
     6001 atcgggatgg acgggttgag ctgcagcgcc agccgtacct cgtccagctc gaacgtcggc
     6061 gccccctcga agcagttgac cgccaccacg aacggcgtgc cgcgccgctc gaagtagtcg
     6121 accgagggga agcagtcggc caggcggcgg gtgtcggcga ggatgacggc gcccagggag
     6181 ccctccgcca gctcgtccca cacgaaccag aaccgctcct ggccgggcgt gccgaacagg
     6241 tacaggacgt agtcgttgcc gagggtgatg cggccgaagt ccatggccac ggtggtggtg
     6301 cgcttggcct ccaccgaggt gaggtcgtcg acgccgatgc cgcggtcggt cagcacctct
     6361 tcggtgcgca gcggccgggt ctcggagacc gcgccgacca tcgtcgtctt gcccgcgccg
     6421 aacccgccgg cgaccaggat cttgatcgcc gtcggcaggc gcggacgctc agagcgagcg
     6481 aagaccatcg agcaccgccc tgtacatctt catgtcgtgc atgtccacct cggatcgggg
     6541 ttcctgggca gagacgagtt cgcggtcgaa caggtcgccg agcagcacgc ggatggtgcc
     6601 ggccggtagg tccaggtatg cggctatctc ggctacggac ttgggttcgc ggcagagctg
     6661 gagtatccgc aggtgctcgg ggtccagccc ggcgtcgggc cctggtggcg ggccgaccgc
     6721 cagggccatg gagatcaggt cgaacctccc gtgggcgggc tgggtacggc cacgggtcac
     6781 cacgtagggc cggatgatct ccggatccac ccagtgctcg tccgtgggct cgtccgcgcc
     6841 tctcaccggt cgctcctggc ggcggcctcg gcggtgcgcg cgccggaggt gaggtactgg
     6901 cccacccgcg cgaccatcat cgccatctcg tacgccacca ggccgatgtc ggcgttctgg
     6961 gcgcacagga cggccaggca ggcccgctcg ccggcggcgg tgacgatgag gaactggttc
     7021 ttccactcca cgaccgtctg ccggaccgca cctgcggaga tgtggtcgga gacgcccttg
     7081 gccaggctct ggagcccgga ggcgacggcg gacaggtgct cgccgtcggt gcgctgcagc
     7141 gcggcggacg aggccatcag cagcccgtcg gacgacagca cgatcgcgtg ctcggcctcc
     7201 ttgatccggt tgaccaggtc gtccatcagc cagttgaggt cggtgcccgc ggtgggggtc
     7261 atgcgtcacc tccttgctgg tcctccagca tcttggccgc ctgggagcgg ccgcgacggg
     7321 tgcctgactg gagagatccc atcatcgcgc ggatctcctc cggcgagcgc tcgtcatcgt
     7381 cctcctcaaa gtcgggctgc gtgggtgtgt cgtcacgcag cgctggcgcc aggttggcct
     7441 ggggcacccg aagggggagc ccccctggtg tgaactcggt cacagactgc tgctccggtt
     7501 cggctggcgt ttcggcttct ggttccgggg cgggcgcggg ctcgggtctc ggcgcgggtg
     7561 cggcctgggg ccggggccga gagtcggggg cgggcccagg ggcgggcaca ggggcgggcc
     7621 caggggcggg aacgggggtg ggcctggtcg ggagcgtgcg cacgttctcg gccgaggccc
     7681 tcgggggagc cgtggtgggc cgggtggcgg tggcgacggc gggctgccgg cgcggcagcc
     7741 gctcccgctc gccgccgtcg tgcgggtcgg gcgtggggtc gagctggacg agctcctgcg
     7801 gcagcagcac cacgaccgtg gtgcccccgt acggggacgc cttgagcacg acctggatgt
     7861 cgtggcgctt ggcgagctgg ctgaccacgt agagccccag ccgggcggtg ccggtgatgc
     7921 ggaactcggg cgggtcggcg atgcgctcgt tggcggcgtc gaggtcctcg ggcttcatgc
     7981 cgaggccgcg gtcctcgatc tcgatcacgt acccgttggc cacgagctgg ccgctgacct
     8041 gcacgttcgt gtacggcggc gagaacgaca cggcgttctc gatgagctcg gcgagcaggt
     8101 ggatgacgtc gccgacggcg cggccgacga gcacgacctc gcccatgggc atgagcgaga
     8161 cgcgggtgta gtcctcgacc tcggcgagcg cgccacgcac cacgtccacc atggggacgg
     8221 agcggcgcca cgtgcgggcg ggggaggagc cggacaggac gatcaggttc tcggcgttgc
     8281 gccgcatgcg gatggcgagg tggtcgagcc ggaagagctc cttcagctcc tcggggtcgg
     8341 tctcgcggcg ctccatcacg tcgagcacgg tgagctggcg gtgcacgagg ccctgggtcc
     8401 tgcgcgcgag gctgagcagg atgtcgcgga tgctgcggcg cagctcggcc tgctcggcgg
     8461 cgacggcgat ggcggtgcgc tgcacggtgt tgaacgcctg gccgacctgg ccgatctcgt
     8521 cgtcaccgaa gtcgagcgcg ggcgcctcct tggcgacgtc cacctcttcg ccgtggccga
     8581 tgcgctcgac gatgccgggc agccgctcgt cggacagctc gtgcgcggcg tcgcgcagct
     8641 tctgcagctg ggcgagcagc gagcgggccg tggtgatgga caggatgatc gaggcgacga
     8701 cggcgatgag cccgagaccg ccggccagga cgagccggat gatcacgttg acggcgacgg
     8761 ggatggtgcg gtcgaccacg cggtcacccg cgtcgagcac catcgtgttg aagtcggtga
     8821 ggaagcgctc ggtcgtcgcc ttccagacct cggccgtgag cggcagggtc agggagttgg
     8881 ggtcgtgctc catgacctgc ttctcgaggg tctggagccg gacggacgac tggcccttga
     8941 tcagcttgtc gtaggcggcc cggtcgaagt cgggcagctc ccgcgcggcc tgctcggcgg
     9001 tgatccgcca gcggccgacg gcctgggcga actcggcctg cgtggcgggg ctcagccggc
     9061 cttcggcgag cgcgccggcc agcagcgcgt cctccctggt gagcagctcg cgggcgcggc
     9121 tgagtgccag gagtgaccgg acgtccttgg cgagctcttt gtcgtcgagc gtggccagcg
     9181 agccgtagac gtcgtagatg gggtcgatga cgtcgtcgta cgcgttcgcg gcctgcgcgc
     9241 ggttgagccg gcccgcgtcg atgctctggc gcagctcctt gagcgagccg agccgcttga
     9301 gcatcacggc gagccgctct tcgccctcgt cgtcgagggc ccagctcacg gcggtggtgt
     9361 cggccgcctc gcggaaggcg gagtgcaggg tgtcggtctc cgcccgctgc ttgtcgagct
     9421 ccttgcgggt ctggggggcc cggtcgccga ggcgggtcag cgagagccgg cgctctcgtt
     9481 gcagggcgaa gagcaggggg tcgctggggg cggacacgga ggagtcgagc tgggagaccc
     9541 acaggaggtt gaccccctcg cggagggtga cccacgcggc gaagacccac aaggctgcca
     9601 gggagagcag catggcagtg atcttggtcc gcagccgcgt cttgcggaag cgcattatac
     9661 ccgtcctgtg aaagtcacat gttcgtttgc cagtcgcccg tcatccgtga cgctggacat
     9721 cgtccggcca tcgtatcgat caaggaactc tagcgcaggg taaagcgccc ctcaagcaac
     9781 gacaatccca gatggcacgg ccttgaccta atatagttaa gtttgacccg tattagggga
     9841 aaatcggtat tcttcgttag tgaacaaccc tgcgtccgca tatttcaaca tccgtaatca
     9901 tcttgccgat gagctccttg aacggtcgca ccagctggcc ggcgtaccgg agcaggatcg
     9961 cggcgccgtc ctggaagcgg cccttgactc cgttcccgac gtgcgggatt tcctgcgccc
    10021 ctaccccgcc ctcttcgccg acggcgacag ctccgccagc cggctggcct tcagctgcct
    10081 ggcggccgcc gccacgttcc cccgggcgcc gcgccggcgg atcgccgacc tcggcgccct
    10141 gagcacgatc ctgttcggcg tggacgacat cacggaccgg gtggcgcagg acgggaccga
    10201 ccaggacgcg ggggagctgt tccgggagct gtcctccgtc ttgtccggtg cgccgcctga
    10261 gggcggcggg acccggccgg tggagcaggc cgtgcacgcc tggcacgcct ggtgcgagcg
    10321 gttccgcacg tacgagggcg ccgccgcgta cctgccggag ctggcccggc agctcgaacg
    10381 caccggcgag gccatggcca gggagcacgt gtgggcgacg ggcggccggc cgtggccgtc
    10441 gtacgaggag tacctgccca acgcgctcgt cacgttcctc taccacacgt ggtggtcggc
    10501 ggccctggcc atgtgcgacc ccgagcccgc cggcaccggc gcctggcggg ccctggagcc
    10561 ggtcaccgac ctgggcgcgg cgtgcctgcg gctggccaac gacgtcagga cgttcgagcg
    10621 ggagcgcggc gagggcaagc cgaacgcggt gctcatcctg gaacgcaccg ggatgagcac
    10681 cgaggcggcg gtcgagcggg tgtccgcgca catccgcgag ctcaacgccg agttcgcggc
    10741 ggcgatcgcg ggcctgcccg ccgagctggc gtgggccgcc gacgggcagt accggtgcgt
    10801 gacgttcagc ggcggctggt acatggccag ggacacgcac gcgtacaccg tgcgtgatct
    10861 cgccgcggac gcggaggctc atcgccgcta gcccgccagc gcctgccgga ccaggtgcga
    10921 ggaggcgatc acggcggcgc gggccaccgc cctgggcacg tacaggtcct tgtcgtgcca
    10981 cagcggcggg tgctcgccgc cggccgggtc caccaggtgc ggctgcccgc gctccgccgc
    11041 gcgcagccgc cgcggctccg cgctgccccc ggtcagcagc agggtctgga tcgcgtacgc
    11101 gctctcctcg gccgtgccct cccagcggcc ccaggagccg tccggccgct gggtcgccag
    11161 cacccattcg gccgccgcgc gcaccgactc gcgtgaggcc tccccgccga aggcgtcgag
    11221 cgccagcgcg cagctcgccg tggcgtagta cggcgaggcg tgccagcggt ccgtccagct
    11281 cccgtccggc cgctggcgct cgcggatcca ggcggccagc tcgccgatgg ccggcgcgta
    11341 ccgcggcgcg gcggccggcc ggcggcggac gtactcgccg aaggcgtcca gcacgtgcgc
    11401 gttgacgctg acggagacac cctgctcgcc cggccaggtg gcgaagtggg tgccggagcg
    11461 gaacgcccac aggctctccg gctcgtgcgg cgcgccgagc agcgccagcg cgtacagcgc
    11521 cacggacgtc gtgtcggcgt cggccggcag cccgggaccg gccggagttc ccgacgggcc
    11581 gatggccgcc cggatgtcgg ccaccatctc gggcggcacg tcgacggtca cccctgccct
    11641 gagcagccag ctcagcaccc atccccgctc gaacacggtg atgggcagcc cgacgggcac
    11701 ggggccgccg aataaccgga ccaccgcctc caggtgcccg cgggccggct cgtgcgcgtc
    11761 gggctccgcc cgctcgccga gccacgcggc ggtcgccgcg ggcgaggcgc cgacgctgcc
    11821 gatcggcgtg ggccggatgc cgggcgcctg ggcggcggcg tcggccgcga tctccagcgc
    11881 gtgcagcagc ttctccggca cctccttgcc cgacctgacc cgcgaccgga cgaggtgcag
    11941 cgcgtcgtag ctcatggccg gcggcaacgg caccggcgag ccctccacgt gctcgttgat
    12001 gcgggccacg agggagggca cgatgtgctc gatcgccggc atgtcgggca ggtcgagcgg
    12061 gccgctcagc caggtggtga gcacccgcag gccgcgctgg gccgcgtcgg cgagccggtc
    12121 gcggcccgcc tcctggtcgc ggcgggtcag cgcggccagc aggccctcgg tggcgctcag
    12181 ggtcggcacc acgccgtacc cgtcgggcgc gccccaggag ccgtccggcc gctgcgtcct
    12241 gatcaggtag tcgatgcgtt cttggtggcc ggtcagccac ggtgcgagcg agaccaggcg
    12301 gcccgtctcg tacaccgagg gcgagacctg cccccacggc cggagcatga ggctcgtgac
    12361 cagctcgtcc gcctgcgcgg tgaggtcgag tgcttcgccg atgctcacgc cgcgcggttc
    12421 cgttcgatcg gctgcaggtg caggaagagc ttctgtttgg gccgcagcgt ggctccgccg
    12481 ggcacgggcc gcagcttctg cgggttggcc acgaccggcc ggtacctgct catcaggttc
    12541 gctatcacca gggacgcctc gatgtagaag agatgctggc cgaggcacac gtgcggcccc
    12601 aggccgaagg ggatgaacgc gtagcggtgc cggcgctccc ccgtgtcgtc cgtccaccgg
    12661 cccgggtcga actccagcgg ccggggccag aactcctcca gccggtgcgt cgtgtacggg
    12721 ctgatcagca cctgcgagcc ggccttgacc gggacgccgc cgatcaccgt gtccgccacg
    12781 gtctggcggg gcacgaccca cgcgttcggg tagacccgca gcagctcctg cagcaccgcg
    12841 cgcaggtagg gcatctcggc gacgtgcgac ggccgcaccg ggccgccgcc caccacgcgg
    12901 tcgatctcct cctggagccg ggcgttgacg tccgggtggt cgtgcagcac ctgccagagc
    12961 cagatgagcg acatcgcggt ggtctcggag gcggcgccgt agatgttgac caggtcgtcg
    13021 cgcacctgcc gcaggtcggc ccggccctcc ttctccagcc tggccgtgag cagcgccgag
    13081 acgacctcct tgccgtcgtt gttctcgcgc ttggcccgct cgatgagggg gtagacgatc
    13141 tcgtcgatct tcttcgcggc gcgcaggaag gcgcggtcgc ccggcagcct gatcgagtac
    13201 gacgcgaacg gaagcagcat gcggaagccg atggaggtcg cgcacgtggc gaactccggc
    13261 gccagcgact cggcggtctc gggggagatc cggccgccga acagcacctt gatgacggcc
    13321 tggttgacga tggaggtcat gtggtgctcg acgtcgatcg ggctgtcgcc gcgggtgagg
    13381 tccccgagcc cggcgacgcg ctcggcgatg atgtcggcca tgtcctcggc cagcgaggcc
    13441 acgtagcggg cggtgaagag cggctgcagg atcttcctgg ccgacgccca gccctcgccc
    13501 tctccgagga tgctctcgtg gccgatcagg cgctgcagcg ggcgccagaa cacgccctcg
    13561 cggacgaagt tggtccagtc cgtcttgagc acctgctgaa cgtggtcggg atgcgagacg
    13621 aggtaggggc ggaagggccc caggtggagc cggacgatct gtcctgaggc gtcggtgccc
    13681 atcctggcca gctcggtgac cgggtcgctc acgagccggg gtatggcccg atgagtggga
    13741 acgacgtgag gactggtcgc gaaggtgccc gtgacgtgcg gcatggcagc gatccccgat
    13801 ccgggtgcgg tgtacctgtg tgactggtgg tgatgatcgg tgcgggtctg gatcaggggg
    13861 ctccccggtg gagccgcgtc cggaggggtg cttgaggtgc ggttaccggg gcgggcgtgg
    13921 cggccgtagc cttgattgcc acaggtgatc cttccgtcgc gtacggtgca cgtctcacat
    13981 cacggacatt ccctgacaaa tgtcaaccga tgggtggagt atcacatgct tgtgcatgta
    14041 gattcaagat cgtacccagg gtaggagcgc cagttgaatc accgtcgtcc cgtcaatgag
    14101 acgaccatgg cccgctgccg cggcctgctc gagccggccc tgcgccaggc cgtgtcggtg
    14161 ctgcacccct ggggcgcccg gatggccgcg ttcgcgctgg gctggtccga caccgacggc
    14221 gggcccagcg ccggcgacgg cggcaagggc gtgcggcccg cgatcaccat gctcagcgcc
    14281 gaagccgtcg gcggcaccgc cgagtccgcc ctgcccggcg ccgtcgccgt cgagctggtg
    14341 cacgccttct ccctcgcgca cgacgacatc atcgaccgcg acgagctgcg ccggcaccgc
    14401 gccgccctct ggaaggcgta cggcgtcggc cccgcgctgc tcaccggcga cgcgctcctc
    14461 gccctggccg tcacccagct cgccgggcgg cccgaggcga tgccctacct gtcggcggcc
    14521 ctgatcgagc tcgtccaggg ccagaccgcc gacatggcct tcgagaaccg cccctggcgc
    14581 ggccccgacg ccgtcaccat cgacgagtac gccgagatgg ccgcgggcaa gaccggcggc
    14641 ctgctcggcg ccgccaccgc cgcgggcgtc gccctcggcg gggcgcccga actggccgac
    14701 cgcatgtggg cggccgggcg cgacctcggg atcgccttcc agatcgtcga cgacatgctc
    14761 ggcatctggg gcgacccccg cctgaccggc aagcccgtcc acagcgacct gcggcgcgac
    14821 aagaagaccc tccccgtgct ggccgccctc gcctccgacg ggcccgccgc ccgcgagctc
    14881 gccgccgtcc tcgcctccgg cacgggcgac gaggagtccg tacggcacgc cgcccacctc
    14941 gtcgaggagg ccggaggccg cgagcgggca cgggcgctgg ccgaccgcta cctgtcgtcg
    15001 gcgctcggcg tgctcgacgc gtgcctgccc gacgcggccg agctgcgcgc cctgtgccac
    15061 tccctggtcg accgcgtcaa ctgaccggct ccctggtcgc ggcttccggt tgggcgcgtc
    15121 acctgactgt tttcgccccg atcgcggaca tcagcagggg gaaggcccgg tgcagctccc
    15181 gctgccagaa cgtgtggttg tgcccgcccc ggtagaaatg ggtgcgaacc gggatgccca
    15241 gctcctccag ccggcccgcg aacgccctgg ccgcccggtt cgccaaatcc tccaccaggt
    15301 cgccctcgcc ggcggccacg tacagccgga cgcccttgag ctcgcccgcg aggtcgtagg
    15361 gattgtgcgc gcgccagacc tcccgctgct cctccggatc gccccagatg cgcttccagt
    15421 cggtgccgaa acagccgagc gccgtgcccg ccatcaccgc ctgcggcacc cccgggctca
    15481 ggatgtgcag cgcgccgctg aacgaggccg ccgcctcgaa gtgccccttg gccgcgtaca
    15541 gcatggcgcc ctgcccgccc atcgagtagc ccgcgatcgc ctgccgcccg cccgcccggt
    15601 agcgcgcctc cagcagcggc cgcagctcct tcaggtggta ggtctcccag cgcggcgggc
    15661 cgccctcgcc cccgttccac cagtcggagt agctgccgca cttgccgccg tccggcatca
    15721 cgaccagcac gcccgtgtcg cgggtgagcg cctccacgtc cgtcttggcc gtccacgagg
    15781 tctcgtcgtc gagcccgccg tgcagcagcc acaacaccgg ccagccggta cgggactccc
    15841 agccgcgcgg cagcagcagg cgcaccttcg tggtcgcgtc gagcgcccgc gacctgatcg
    15901 tcagctccat cctgcgctcg tccagccgcc gctcggccac gatttcggtc gccgacggag
    15961 acggttgcgg acggggcgtt tcccgcccgc cgggccgcag cacgaccatc accaccagga
    16021 ccgccagaca cagaccagcg gcgatcaccg cgccgaccag gcatccgagt aaccggggcc
    16081 gcatcgcagt ctccttgttg gatgtgcgga taatagcggg atgagatcaa taggcaccac
    16141 ggacctgtcc gtgttcccga tagcgctcgg caccaacgtc ttcggctgga cggccgacaa
    16201 ggagacgtcg ttcgcgatcc tcgacgccta cgtcgacggc ggcggcaact tcctcgacac
    16261 cgccgacgtc tacccctact gggccacggg ggagtccacg tccgagacga tcatcggcga
    16321 gtggctggcc tcgcggcgca accgcgactc gatcgtgctc gccaccaagg tcggcatgct
    16381 cgaagggctc cgggggctcg cgcccgccac gatcaggacc gcggtcgaag actcgctgcg
    16441 gcggctgcgt accgactaca tcgacctcta ctgggcgcac gtggacgacc acgacacgcc
    16501 gctggtggag tcgctggccg cgttcgacgc gctcatccag gagggcaagg tccgccacat
    16561 cggggcgtcc aactactccg cgccgcggct caccgaagcg ctcaagacct ccgacagcga
    16621 agggctggcc aggtacgtcg cgctgcagca gccgtacaac ctggtggagc gcgactacga
    16681 gggcgagctg cgcgacgtcg tcgcgcgcga agggctgtcc agcgtgccgt acttcgggct
    16741 ggcgcgcgga ttcctgaccg gcaagtacgc gcccggcgcg cacgtggaca gcccgcgggc
    16801 gggaaaggcg gccgaatacc tcgacacggc ccacgggccg cgcaccgtgg aggcgctggg
    16861 gcggctggcg gaggagcggg gggtcgcgcc cgcgtcggtg gcgctggcct ggctcgccgc
    16921 ccagcccacg gtcacggcgc cgatctccag cgcgcgcgac ctggcgcagc tggggccgtt
    16981 gatggaggcg gcggcgcttt ccctgagcgc cgaggaactg tccatcctcg acaccgcctc
    17041 ccgcccctga cggcgttttc tcgcccggcc ccctcgccac gtggtgcggg cgacgagggg
    17101 ccatgggggc tatgagaggc ggccatgaga ggcagccgtg ggggacgacc tgtggggggc
    17161 ggccgtgggg gcgtggcagt gggggcgtgg cagtgggggt gcggccctgg ggcatcacgc
    17221 caggctgttg ctcccgcacc actcggcgac gctgcccgcc gcgccctcca cgacctgctt
    17281 ccagtgcgga tcggccgtga tcgcgtcgtg gacggaggag tgggaggcga acacggcggt
    17341 caggccggtg atcttgaaga tgcgcgagat gcggtccgtg gtcatgacga gcgagagcgt
    17401 gccgtcctgc gtccgcagcc gcttgagacc gccgacgagc acgcccagcc cggtcgagtc
    17461 gaggaactgc accgcgctca ggtcggcgat gacgtgcacg gtgcccttgg ccgccaggtc
    17521 gatgatctgc tcgcgcagct tgggcgcggt gaacacgtcg acctcgccgg cgaccttgag
    17581 cacggcgcag tcgccgaccg gtccgaccac ctcaatgacg atgtcctgca tttcgcgcct
    17641 caccatcgct catgtcatcg actacattga cggggaactc tctgcattta cacagtactg
    17701 cgacgctcac ggtccgtcaa tggctgactg tcggtgtcat cctgcacaat gacaagtggg
    17761 ctggagaggt gcaggatacg gggagaagct ggagaggtgt ggggatgcgg gtagaagagg
    17821 ccatcgggcg gcagatcgcc cggctgcgcg ccgaacgccg gatgtcgctg accgagctcg
    17881 gcgaagccct cggtcgctac ctcgaccggc catggagccg ccaggccgtc caccaggccg
    17941 aacgcgggca acgctccttc accgcagcgg agctgaccgc cctcgccctc gtcctcgaca
    18001 cgtccgtccc ggtgctgttc cgcgccgagg aagaccgcat cgaactcccc ggcggcgccg
    18061 tctccccgga ggactaccgc ggaatcctcc tgaacagaga gccggacatg ccgctggacg
    18121 gggtggagga gctcatcgtc gccctgcacg acatcggcga ggtcctggcc cgcccggccc
    18181 tggcccgcct ggcccgcatc ggccgcgtcg ccgaccaggt cgccggcccc gaccgctaac
    18241 ccccacgcct tccccgcccc ggccgccgcg ccaccggccc ctacgccttc ccgtcccggc
    18301 tgccgggccg cccgccccta cgccttcccg tcccggctgc cgggccgccc gcccctacgc
    18361 cttcccgtcc cggctgccgg gccgcccgcc cctacgcctt cccgtcccgg ctgccgggcc
    18421 gcccgcccct acgccttccc gtcccggccg ccgggccacc ggtccctacg ccatgctgcc
    18481 agcggctggc cattcgccga ccgcactccc atccgtcccg ctgccgccga ccccgcactc
    18541 gcccgccggc cccgctgctg cgcctcctcg ctttcgccgc gttatgcacc ccagccgccg
    18601 cgcccgcttc gcgctgccgc gcccgcttcg cgcacccctt cgcagctcga tcggccccgc
    18661 gcccctgccg cgcacgccga gttccgcgcc gctcgccacg cccggcgcga ctccgaccca
    18721 cccgccgcaa cccgtgcgac ccatgcgccg cccgccccgg ggttcgcgcc gctcgcgccg
    18781 cggggttctg cgccctgcgt cacgatcggc gccccacgcc tgcgcctgta cctcccgccg
    18841 gggccgcccg agcctccgct cgcctagcaa cccgcgtcca gcctcgcctc gcccagcacc
    18901 ccgcttgtga gtccctgcgc ccttgccccg cccctcgtcg cccagcgccc gccgggtcag
    18961 gcaccccgca tcacgatcgg cgccctccgg ccgcgcttgc acctgccgcc ggggccgccc
    19021 caacctccgc tcgccccagc accccacgcg cccagcctcc gctcgcccag cctcggctcg
    19081 cccagcctcg gctcgcccag cctcggctcg cccagcctcg gctcgcccag cctcggctcg
    19141 cccagcctcg gctcgcccag cctcggctcg cccagcagcc cgccgccccg cacccgatgc
    19201 ccccgcaccc ccgtgtcccg acccccgtac tcagcgcctc gcatccgtgg ggcgcccgta
    19261 ccggcccgtg cctccctcgc ccccgaccgc gcgcgcccga cccctctcac gcacccgccc
    19321 cctgtgccac cctcggcccg gcgggcccgt gtccaggtca gtggtggtcg gcggcggaca
    19381 agtcgaggtg gcggggggtg agccaccaca ccaccagcgc ccccaccgcc agcagcagcg
    19441 ccgcgacccc gctggtcagg gtgagggagt tggtgaacgc cgcggtggcc tgctcggcga
    19501 gccgtccgcc cgccgccccc agttccttgg cgacgtcgag cgccccgccc agcgactccc
    19561 gcacgacgcc ggccccgggc cccgagtacg tcacctcgct ccggtaggcg gcggcggcga
    19621 cgcttccgag gacggccacc ccgagcgctc cgcccagctc gtagctggtc tcctcgatgg
    19681 cggccgcgct gcccgacttg gccggtggcg agccggacat gatggtggcc gaggcgatgg
    19741 cgagcgaccc gtttccgagg ccgacgaggg tgagggcgac cgcgacggtc cagtacccga
    19801 gcgggcccgg cacgacgaac agcagcagga acgccacccc ggtcagggcc agcccgccgg
    19861 cgagcaccgt acgggctccg atgcgggcgg ccagcgacgg cgccagcggt gaggcgatga
    19921 cggcggccag cgcggcgggc agcagccgga cgccggcctc cagcggcccg tacccttgga
    19981 cgagctgcat ccactgcgcg agcagcagca atacggacgc catcgcgatt gacgtgatca
    20041 gcgccgtcac gacgccggcg gagaagggcg cgctgcggaa gagccggagc tccagcagcg
    20101 gatcgggcct gcgcaggcac cgcaccgcga accagcccag cgccaccacc gccaccacgc
    20161 tcgccacgag agcgccgggg gaggtgaggc cgtacttgcc gaagttcttg atcgcgtaga
    20221 cgagggcgac catgccggcc atggacagca gtgtggccag ggcgtcccag cgtccgggcc
    20281 tcgggttctt ggactcgggc agcaggaaca ggccgaacgc gatggcgagg accatgacgg
    20341 gcacgttcac gaggaacgcg gcgtgccagc tgaagtgttc cagcagcacc ccggccacga
    20401 gcggccccag tgcggcgccg acggcggcca tggccgacca cacgccgagg gctttggcgc
    20461 gttcggcggg gtcggtgaac aggttccgga tcatggacag cgtggacggc atgatcatgg
    20521 cgccgccgac gccgagcagc gcccgtaccg cgatcacctc cagcgggctg tcggccgcca
    20581 gcacggtcgt cgacgccagc ccgaacaccg cgaaccccgt catcagcatc cgcttgcggc
    20641 cccaccggtc gccgagcgcg ctcacggtga cgagcagccc ggacaggacc agcgcgtacg
    20701 cgtccaccat ccacagcagc tcgatggact ccggccgcag gtccgccgag atggcgggca
    20761 gggcgacgtt caggacggtc atgtccatga cgacgagcag cacgctggcc gacagcaccg
    20821 ccaggcccgc ccatcgcctc ctcgtcggga cggccggcgt ggtgatcgtc atgctcgctc
    20881 cttctcgggt gcggcgccgt gcaggaacgt gtcgagcagc agcctcgcca cgtcccggcg
    20941 ggcgacgtcg ccgttgcgca ggctctcccg tacggccacg agcagcccga acacggtgtt
    21001 gctgatccag cgggccggca ggtcggcccg cagcaggccg gcgcgctggg cggcggcgta
    21061 gaagacgacc tcgcgctcct ccagctcgtc ggcgcgccgc ttcagctcgg ggtgagtggc
    21121 gagacggtcg tcggtcaggc cgaacccgta ctcgtcggcc acctcgatca ggccctccag
    21181 cagcgctttc agcgctcgct ccagcgccgc ccggtcctgt gacgcggtgg cggccaccat
    21241 gccgctgctc gtctgcaggt cctcccactg gtcgtgggcg cggtgggcga gggccagcat
    21301 caggtcgtcg cggctgctga agtggcggtg cagggtggcc ctgctgatcc cgaccgcctc
    21361 ggcgagctgg gccatggacg cggccgggct ctcgttgagg tgctggatcg cggccttcat
    21421 gatctggtca cgtgtcgctg ccatgatgga cacctacgta ttgtttgaga caatttcgtc
    21481 tcacatgcta catcaccgac tcggacgggc gggggcgacg agggctcggc gaaagggccg
    21541 agcagagctc ggcaccggcc tctccctctc cctctcccgg gagatggcga tcgggccgca
    21601 ggtggggcta tggtgcggag ctgtgatgag cggtgacgcg cacacgcgca acctgaacga
    21661 cgcgcacccc cgcatcctga acgacaggcg cacgcgcatc ttggacgatg ggcacccggg
    21721 catcccggac gacgggcgca cgcgcatctt gaacgacgga cacccgggca tcccggacga
    21781 tgggcgcacg cgcattccgg acgaccggca cccgggcatc ccggacgacg ggcgcacgcg
    21841 catcttgaac gacgggcgtc cgggcatccc ggacgacggg cgcacgcgca tcttgaacga
    21901 ggggcacccc ggcatcctga acgacgtgcg tacccgcatc ctggacgcgg ccgaggagct
    21961 cttcgcgtgc ggcggttacg cggccacccc gaccacggtc atcgccaaac tcgcgaaggt
    22021 ccccggcgac ctgatctccc agtacttccc gcgcaagatc gacgtactgg tcgccctcgt
    22081 cgacgagcgc acgcacgtcg aggagaacga ccaggtcgac gccgtgccgg gcgacctggc
    22141 gggcacgctg tccagactcg cgcgcgtcct gccgctgcgc gcctcgcccg cgatgcggcg
    22201 catcctgtcc cgggaggccg acacgcacgg ctccgtcaag gaacgcctcg gacgcctcaa
    22261 cggcgagctg gtcaggcgcg cccggttcgc cctcggcctg gccctgcccg gcgcgcgcgg
    22321 cgacgcggcc cggctggagg tggcggccgc cacgttcgcc gccatcctca tctaccagga
    22381 gaacctctgc cagctaaccg gccaccagat cgaccccgac gccgtcgcgg aactcatcgc
    22441 ccactcgctc gtctagcaac tcgtcgagcg ccgtacgcag gtgcaccagc aggccccaca
    22501 catcgtccac ccgctcgggg caggccacga tgccgaagtc gagcatgccg tcgtacgaga
    22561 agcaggtaat gttcaggccg ccgctcaggt cggtcagcac cgacagcggg tagtacgaca
    22621 ggatccgccc gccgcacagg tacaggggga actgtgggcc cggcacgttg ctgatgatca
    22681 ggttgatcgg cgggaacgcc atgcccgcca accggaagat cgccggcgtg gcgagactcg
    22741 tgaccggcgt cggcaggatc gagcacagct cgctcaacca cgtcgccgga gccaccgcga
    22801 agcgccgctt ggcccggccc atcgcggcgc ccacctcccg cagacgctcc ttcgggtcgg
    22861 acaggtgcgt cggcacgggc gccaccatcg ccgagatctg gttccccacc aggtccttcg
    22921 cctgcgcctt acgcaccgcc accggcaccc ccacgaccag cggcgcctcc ggcaacgcgt
    22981 cccgctcgca caaccacgag cgcagggccg acgtgcacag ggtcatcacc acgtcgttca
    23041 cgctcacgcc gttggccttg gcgaccttct tgacgtcctt gagcgacacc gagccgaacg
    23101 aaaggtgacg gcgagcgctg atggggccgt tgaacggcgt gcggggggcg gcgagactgg
    23161 gcaactcggg ccgtcgctgc ccttcacgcc ccaccatccg cgccgccctg gccaccagcc
    23221 tcgcccccgg caacccgccc acgacgggga tcacatccag atcccccgcc gccctcacca
    23281 ccgaccggac cgcacggacg ggctgggtag cgctccgcaa cacggccccg gccaacatgc
    23341 caaccagacc aggcgcctcg tcacccacgc tgcccacacc actgtccacc tgcccggtgt
    23401 cgtcagggct agcaccgatc agactcacgt cgtccggatt ggcgccgttc gggctcgtgt
    23461 cgttcgggct cgtgtcgttc gggctcgtgt cgttcgggct ggccccgttc gggtgggcgc
    23521 cggtcgggtg gacgtcattc gggctggccc cgttcgggtg ggcgccgttc gggagggcgt
    23581 cgtccgggtg ggcgccgctc aggcgcgcgt cgttcgggcg agcgtcattc agactcccgc
    23641 cgtccgggct cgcgttgttc aggcaggcgc cgttcgggct ggccccgttc gggtgggcgt
    23701 cgttcgggct ggcgttgttc gggtgggcgc cgtttggacg cgcgttgtcc gggtgggcat
    23761 cgtgcaggcc cgtgccgtcc ggacgagcgt cgcgggccgc ttgcctggac ctgctggaac
    23821 ccgcccgagc cgacccggcg cggcccccac gcacggcgac accggcacat gcacctccct
    23881 cacccaccgc cccgccttcg ccgccagcgg ccccaccatc gcggcccctc gccggcccgc
    23941 tctcaccgtt gtttgccccg ccaccgctga ccgcttcggc gctctcgctt accggcgtgg
    24001 agtggcgtct gggggtcagg tggccgtcgg gggtcaggtc gagcagggtg gcgagggttt
    24061 ccgcgcctga gatgccgtcg atcgcggcgt ggtgcacctt cgtgtagacg gccaccagcc
    24121 cgtcgttcag cccgtggatg aggtgcatct cccacagcgg gtgcgcgcgg tcgagccggc
    24181 gggcgtggag ctgggcgacg gtgtcggcga gctgccagtg gtcgcccggc tcgggcaggg
    24241 tggtctcgaa gaggtgatgg tcgaggtcga agtcggggtc ggcggcccag taagggtggt
    24301 cgaggcggag cggcacctcc gccaggcgca ggctgagcgc gggggagagg tggatccggt
    24361 cgaggaggag ctccgccagc gcgctcctgg tgaccgctcc gtccgccggg tcgaggatcg
    24421 ccaggcccgc cacgtgtgcg gcggtcgtcg gcgtctcgac gttgaggaac tgggcgtcga
    24481 gtgcggtcag ctggcgcatc ggctctcctt ttccctggga tggacagcat cacatgaagg
    24541 gatttccgga aggtttccgg ccgagtcttc cagatgaatt cgagtgcgcc gtacgcggga
    24601 taaaggaatg ctccagctca gcccggatcc gtgacaattt cctatccatt gacgacgtga
    24661 atggggtgtt ggacgacggc gtcgaagtgg tatccgaacg ggtggcgcgg cgtggtgagc
    24721 ggttgcgtgg cgcccgtctc gtcggtggcg cgcgccatga gcaggcgggt gcccgtacgc
    24781 cgtggagccc acgcgacgtg ccagggcaac caggccttga ccaggtgctg accgtggtgc
    24841 tcggccgtcc gccaggtcag cccgccgtcg aagctgacct ccacccgcac gatcctgccc
    24901 cgccccgacc atgatcggcc gtgcaggatg tgcgggcccg cgacgggcag tcgcgcattc
    24961 caggcaagct cgaacgcgct cttcaccggc tgcgtcgtga cgtccgggta aaagaccgtg
    25021 ttccacggcg tgaagagcgg ttcagtggaa acttctatgt caccgagcca tttgatggac
    25081 gctattccca cccatcccgg caccaccagc cgtgctggaa atccgtgatc gggcgggagc
    25141 gggactccgt tcatctcgta cgcgacgagc acgtcgtcca tggccttgcc gatggggagc
    25201 ggccggcgta cgtgcccgtg ctcctcgaac ggcgcgtcga gcccgacggg cagcacgtcc
    25261 accgcctccg gacgtacccc ggcctggtcg agcaggtact tgagcggcac cccgcgccac
    25321 cgcgccaccc cgatcgcgcc cagcccccac tgcgtgccgg gggcgccgtc gtgctgctgc
    25381 gtccggtaga agcgccggcc gttgcccgcg cactcgatcg ccacgtcgta ggtgcgcgac
    25441 ggcatggcgc gcagctcctc gtagctgaac gcgcgcggac atcgcacgcc cgccccatgg
    25501 atgcccagcc gccaggtggt gacgtcgatg agcggggtga aggtgtggtt gcggacgaag
    25561 aaccggtcgt tgggggtgtg gtagccgaga cccgccatgg cttcccagcg catctcggcg
    25621 ctgttgccgt gcaccttgaa caggtggtcg ggcaggggct tcacgatcgc cgcggtggct
    25681 tgcttcatgg agcatcacct cttaatacct atttcctacc tggaaaccat ttaatctcct
    25741 cgtgctgtct ccgcgcgccc ttcattgcca aaatgtgtcc cagcgctggg ggaacgttcc
    25801 atccagcgcc actcctggtc ccctacccga gccccgagcc accccaacct ccagccgagg
    25861 cctacggggg caggtgcggg tttttggtgg ggacggagga ggtgacggcg ttcgggggcg
    25921 gtcgcaaggc ggacgggtgc tgtccctgtg gtgtctgcgc tcgagaaggg gctacgcggg
    25981 gctcaccaga cttgcgaacg gggtgccggt gttgaggtgc tcgatcaagg agaggaggcc
    26041 cgtgcggtct ccgttggcgt gtaaccagcg ggatacctgg caggcggact tggcgtaggt
    26101 gttcgcgtcc ttgctcgccg tgctcagcca ctcgtccagc gttgccggga gcgggcccga
    26161 cggggaggcg aggcagcggt cttcggtcgt cttcggggcc aggtagcggg ggtcgtcgga
    26221 gaccacgacc gccaggccct cgtcgaacca ctgggggacc tccgcgccgg acgtgagcct
    26281 ggtgtgcagc tctacgtggg acatctcgtg cgaggcgatc accgggtcga ggcccctcgg
    26341 ggacagcatc accgcccggt tgagcaccgc gatgccgcgc tccttgccgc ctccgatccg
    26401 ctcgtagcag ccttccgtga cgcagacgag cagggtgggg gtgctcgtct ggctgccgta
    26461 gaaggcggtg acgcggtggc gggcctccgc gatcgtctgc ttgacctggg cctgctgtgc
    26521 ttctgacagg ccgtcttccg tgtagacgga atcctccagc tccgtcaggc cgtagcagcc
    26581 ggggcaggtg gtcgcggcca gtgaggggta ggccagggct actccggcga gggcggcgac
    26641 gagcagggcg gccagtactg cgaacacgcg cgccagcagg gtgcggggct tctttcgcgc
    26701 ggagtgcatc ctccggggtt ctccttctgg gtggggcggg gcggctggtg aggacagctt
    26761 ctcgcaatcc cgggatcggc acatcggacc agggtttgtc attctctggg tggatgcgct
    26821 cctgggggag gcggcgggcg cgcggctgag gggtggcgtg ggcggccgtg tggtgaggcg
    26881 ggagcgtggg aggtgcggag gggcttgggt gggcttcaag aggtgcccaa aacatccgtg
    26941 tatatggcgt taagtcggta ttggggagaa ggggaggggc ggagacctgt ctcgtcgaaa
    27001 ggggacggtt catgggagtc gccggacgcc ttctcgcggg tgccgtgcca ggccttctcc
    27061 tcggtgtcgc gctcgccgtc atccccccgg ccccggtcgg cgccgactcg gtcagtcggt
    27121 cgccgacctg ccggtacgtc aaccagaccc acaagccggc ccccgtgagg ctcgggccgg
    27181 gcaagaagta tcggaagacg gccgagttgc ctccctccgg cgagccggtc aaggccacct
    27241 gtgcggccag agggcggggg ccggagcact gggtgcggat caaggagggg gagcagaagg
    27301 ggcgctgggt gtggcggaat cggctgcagg tctggaacgg ggagtgatca ccggccagtg
    27361 gtcaccggcc caggaaggcc agcaggcgct ccagcggcca cgtgttgatg acgtcgtcgg
    27421 aggtgagcca ggcccgctgg gcgatgccga cgccgaagcg ctggtgcgcc aggtggggga
    27481 tcgcgtggga gtcgctgtcg atcgagaact tcaccccatg gtgcttggcc aggcgcacca
    27541 ggtcggacgg caggtcggag cggtcggggt aggagtcgat ctccatggcc gtgccggtgc
    27601 gggcggcggc gcggaagacg gcgtcccagt cggcgtcgac gggctcgcgc ttgccgatct
    27661 tgcgggtggt ggggtggcca atgatgtcga cgtacgggtt ttcgcaggcg gcgatgaagc
    27721 ggcgggtcat ctcgtcgcgt gactgggtga agtgcgagtg gaccgacgcc acgcacacgt
    27781 cgaactcccg caggatctcc gcgggccagt cgacggagcc gtcgggggcg atgttgagct
    27841 cggagccgtg caggatgcgc atgtcgggat atttcgcttg cagctcggcc acgcggcccc
    27901 gctgctccag cgccttgtcg agggtcatgc gctgcatcgc caggtcgggg gcgtggtcgg
    27961 tgaccgcgta gtaggcgtag ccgcgggcgt gaccggccgc caccatgtcc tccagggacg
    28021 cgatgccgtc ggtcaggtcg gtgtgggtgt gcaggtcgcc cttcaggtcg gccagctcca
    28081 cgagcacggg cagctcgccg gcgagcgccg ccttcacctc gccgccgtcc tcacgcatcg
    28141 gcggcggtac gtactgcatg ccgagcgcgt cgtagatgtc ctcctcggac tcggcggcga
    28201 tcacccgctc accctcgaac aggccgtact ccgacagctt ccagcccttc ttgaccgcca
    28261 tctccctgat ggcgacgttg tgctccttgg agcccgtgaa gtactgcatg gccgcgcccc
    28321 acgagccggc cggcaccacg cgcaggtcca cctggatgcc ggacgtcgtg cggatcgagg
    28381 tcttcttgtc gccggcggcg atgacgtcgg cgacgtacgg ctgggcgcgg aagtcctcca
    28441 tgatggagtc gggggccacg gccaggatgt cgatgtcgcc gatcgtgtcg cgcatgcggc
    28501 gcagcgagcc ggcgtacgcg atgcgctcgg ccttcaatga cgccatcacc tgctcggcca
    28561 gcgacatcgc gacgccgatg tgcacgcggc ggcccgactg ctccagctgc tcgatgccct
    28621 tgagcaggtt ggccagggtc ttggggccga ggcccttgac gccgtcgagg cggcccgagg
    28681 tgatcgcctc gctcagcgcg gtggtggagt cgatgccgaa gtcctcgaac agcatgatcg
    28741 cggtcttggg gcccagggac ggcaccctgg tcagccggcg cacgccgtcg gggacgcggc
    28801 cccgcaggtc gtcgagctgg cggaagctcc cgcgctccag gaactcctcc atcttcttgg
    28861 cgatcgcctc gccgacgccg ggcacggagc gtacgtcgac gaccgagatg tcctcgggga
    28921 acccggcgat cgccttggcc gccttctggt agctgcgcac ccggaaggcg tcgccgccgg
    28981 agagcgcgaa cagctccgcg tattcctgca gcgccgccgc cgcttcctcg tttgcccgca
    29041 tgacccatac cttagggggc cgctccgaca atcctgccca ggcggtgacg cccccggcga
    29101 cgcgggccag gggcgaggga gcccgggtgg gccggccggt tcggaagaag ccggcccgtt
    29161 cggaagaagc cggcccgttc agaagaagag cgtcagaagc ggacctcgcg cgggcggtag
    29221 ggctcctcca ggaaggccgc ttcctccgcc gacaacctca ccgaaacagc cgccaccgcg
    29281 tcgtccacgt gccgcggttt cgtggccccc acgatcggcg ccgtgatctc gctgcggtgc
    29341 agcacccacg ccagcgccac ctgtgcggcc ggcagcccgc ggtcggcggc cacctgggcg
    29401 acccggtcga tgacgagctt gtcgttctcg gggtcgtaca ggtagtcgat gcgttcgtcg
    29461 gagccggtgc gggcggtggt ggcggtggag ccggccctgg cgagcacgcc gcgcgccagc
    29521 gggctccagg ggatgacgcc gacgccctgg tcggcgcaga gcggcagcat ctcgcgttcc
    29581 tcctcgcggt agaggaggtt gtagtggttc tgcatggaga cgaacttcgt ccacccgcgg
    29641 gactcggcga cgtgctgcgc cttggcgaac tgccaggccc acatgctgga cgcgccgatg
    29701 tagcgggcct tgccggccct gacgacgtcg tgcagcgcct ccatggtctc ctcgatgggc
    29761 gtctcgtcgt cccagcggtg gatctggtag aggtcgacgt agtcggtgcc gaggcgggtg
    29821 agggaggcgt cgatggcgtc catgatgtgc ttgcgcgaca ggccgccgtc gttgcggccc
    29881 ttgcccatgg ggaagaacac cttcgtggcc aggacgtagt cctcgcgcct ggggaagatc
    29941 gcgcgcagcg cggcgccggt cacgacctcg ctggcgccgg cgctgtagac gtcggcggtg
    30001 tcgaagaacg tcacgccggc gtcggcggcc cggcggatga ggggctccgc ctcgtcctgc
    30061 gcgagcgccc actgctgctt ggcggggtcg ccgtagctca tcatgcccag gcacagccgc
    30121 gagaccttca agcctgagtt acccagtcgc gtgtactcca tgaagctcac catatgacca
    30181 gatatctcgt ggttgaccag gagggtggcg cggaagtcag ggctgtccaa aagcggaaat
    30241 gacctttaca cgggcgacac ggatcgggtc gattagagga acgttgcaaa acggtggggt
    30301 gctctggcga cgtggcagat caggcggacc cgaacgcata ccgggggtga ggtggaagaa
    30361 acacaccgtg ggctcgtgtc tcgggcgcgt tccagactcc acgaaagccg tgccaagctc
    30421 cacaaaagcc gcgtgacctt ccacggccgg cgggccaagc tcagggatct gcgtgcccgg
    30481 ctcaatggcc cctcctgggt gggcgggctc gggctggcgg cggggatcgc cggcctctgc
    30541 gtgccggtcc tggcgggcct ggcggcctcg aaggcgctgg ccgggggcgc cgtcgcgctg
    30601 gtcgtcctgc tgggcctgca cgtcgcgttc attaccgagt ccccggtacg ccgtgcgggc
    30661 gcctggtgga tcgtggccgt gcaggcgtgg ctgacgtacc tgccgctgac gatgttcggg
    30721 gcggcctgga ccccggtctg cggcctgctg gcgggcgcgg tgctggtgat ggcggcccgg
    30781 atccgctccg tcgtgctggt gctgctggcc ctggcctgcg ggccggtggt gctcgcggcc
    30841 cccgaccgga cgatgatcga cccgctctgg gcgctggccg ccccgctgac cggcctggcc
    30901 gagtacgcgg tgatcacgct gacacagcgg gccaggcggc tcggcgaggc gcgtaccgag
    30961 gtgatgcgca gagcggtggc catggagcgc cgccgcttca cccgcgacct gcacgacctg
    31021 gtcggccacc ggctgacggt gctggtgctg aaggtgcagc tcctggagcg gctggtcgcc
    31081 gagggcgacg agaaggcgcg ggtcgaggtg agcgagacgc tggagctgct gcgcaacctg
    31141 tcggccgatg tgcgcgcggt ggcgcacggc ctgcgcagct cctcgctggc ggccgagctg
    31201 ggctcggcgc gctcgctgct ggagtcggcg cgggtgcgct gccagatcag ggtgtcctgc
    31261 cgcgacttac ccggcgccgt ggaggaggcg ctcacgcacg ccttgcgcga gggcgtcacg
    31321 aacgtgctgc gccacgcgga ggcccgccag tgctccgtgc atctgttgga acgtgaccac
    31381 atggtccgcc tgacgatcag gaacgacggg gtgcgcccgc cgcgccgccc cggcgacgcc
    31441 ggccagggcc tgctgaacct ggccgaccgc gtctccgcgc tcggcggctg gctcgaagcg
    31501 acctcgtcgc ggaccggtca attcacgttc agcgtgtacg tcccacgaaa gaaataatcg
    31561 tctaccggtc aatgatgcga tgttcacaaa agccattgaa atagccatgt atcggtgctg
    31621 aagaatgtga ctagccggac gccccccggc ggcgggaagc tactggacac accgccctgg
    31681 aggtcccggc cagatggaca agtacgagct gtattgccta gtcgacccgt gcttctacga
    31741 caacctcgag cacagcacgg cgacggacgc cgactttccc attctgcgcc gcccgctgcc
    31801 tgccggctgg tcctcggccc gcaccgacac ctggtgttat ttcgctccgg acagcgacac
    31861 gccgctgccg gcgcagggct ggaagattca cgtgtcggcc cgcgtcgagg acgcggaaaa
    31921 ggccatcgaa acggtgtggg actactgcat gccgcgcggc gtcgcgttca agttcctgcg
    31981 cgggctgccg gtcctggtga tggtgaactc caaggccgcc tcaagggcct ccagcggcaa
    32041 gctcgtcacc ctttacccaa gggacgaggc gcagctcgaa ctcgtgctga aagagctcga
    32101 cgagctttta cgcgacgtgc gcggcccgta catcctgagc gatctgcgtt acaacgaggg
    32161 cccgctgttc gtcaggtacg gcggtttcgc cgagcggcac tgcctgtcac tgacgggcga
    32221 gcgcgtgctg gccctggagg acggcgacgg ccggctcgtg ccggacgtgc ggggcgccac
    32281 gttctcggtg ccgccgtgga cgacgctgcc cgcgttcctg gagccgcagc tcgccgcccg
    32341 taacgccgtg acgacgaccg ggctgccgta cacgatcgag agcgtcctgc acttctccaa
    32401 cggcggcggc gtctacctgg gccgcgacaa gcggaccggc gagcgcgtgg tgctcaagga
    32461 ggccaggccg cacgccgggc tcgacgcggc cggccgcgac gcggtcgcca ggatcgagca
    32521 cgagcgcgac atcctcgaac gcctgtccgg cctgccggcc gcccccgcgc tgcgcggcta
    32581 cttcacgctc ggcgagcacc acttcctcgt ccaggagttc gtggacggca cgccgctgca
    32641 gcgccggctc gtgcaccgct acccgctcac ccgcgccacc tgcaccgagc gggacctggc
    32701 cgagtacacc gagtgggcgg tgcggacgct ggaggaggtg acccgcgcgg tcggctcgct
    32761 gcacgagcgc ggggtcgtct tcggcgacct gcaccccgac aacatcctgc tgaccgacga
    32821 gggccgggtc gcgctgatcg actacgaggt ggccacgctc gccgaggaca gggcgcgcgc
    32881 cgcgctcgcc caccccgcct tcgccgcccc ggccgaccgc cagggcgtgg acgtggaccg
    32941 gtacgcgctg gcctgcctgc gcctcggcct gttcgcgccc cagtgcacga tcatgctgcc
    33001 gctgcaccgc ccgaaggtgg tgcacctcgg ggagatcgtc aaggagacgt tccccgtgcc
    33061 ggcgagcatg atcgacgggg ccgtcgcgac catcgccggc ggcgagcggg acaccgccgc
    33121 cgtccccatg ccgggcgtgg cgagctggcc cgagctgcgg aacgccatgg ccacagcgat
    33181 cacggccgcg gccacgcccg ggcgcgacga ccggctcttc cccggcgacg tcgcccagtt
    33241 ccagcccggc ggcgggctca acctcgcgca cggagccgcc ggcgtgctgt tcgccctgca
    33301 cagcgccggc ctcgggccct accccgagta cgagagctgg ctgcgcgagc gcgcccgccg
    33361 ccccgtccag ggctccgggc tcggcctgta cgacgggctg cacggcatcg cgtacgtgct
    33421 cgatctgctc ggacaccacg aggacgcgca cgacctcgtc gagatctgcc tgcgcgagaa
    33481 gtgggaccgg ctggaatcgg cgctcatctc cggcctgtcc ggcatcgggc tgaacctgct
    33541 ccacttcggg cacaccgacc tcgccctgcg cgcggtggac atctgcgccg gccggctcga
    33601 cacccccgtg cccgagatca gcggcggcac caatccgcgc gccgggctca tgcacggctc
    33661 gtccggcccc gcgctgctgt tcctgcgcgc ctacgagcag accggcgacc cggcgctgct
    33721 cgacctcgcg gccaccgcgc tgcggcagga cctgcggcgc tgccggcact cggaagacgg
    33781 ctcgctccag gtcaaccagg ggtggcggct gctgccgtac ctcgacgagg ggtccgcggg
    33841 gatcgccctc gtgctggagc gttacctgcg gtaccggcac gacgaggcgt tcgggacggc
    33901 gctggccgag ctgcggctcg ccgggcgcgc gggcttcttc gtgcaggccg ggctgttcac
    33961 cggacgcgcc gggatcatcg cggcgggcgc cggggacgtg cccgaactgg tgaaggggct
    34021 gcgctggcac gcgctgccgt acgcgggggg cctggccttc cccggcgacc agctcctgcg
    34081 cctgtccatg gatttcgcga ccggaacggc cggcgtgctc ttcgccctcg cctcggcgct
    34141 gggcgacgga ccctgccatc tgccgttcct ggaggccgca cccgagcggc ctctccccga
    34201 cgacaccacg gaaggaggtg tacgacatgg ttcttctcga cctgcagggt cttgaggctc
    34261 ccgcggccag cgacgtggcc agcggcggca gcacgctgac cgttctctcc tgccactccg
    34321 gcaagcccag caacctcagt gtcgctctgt gccactgatc ttgcgcataa aggtccccgc
    34381 gccgttcacc acggcgcggg gacattgacg gtgaaggagg cgtcacgttg cgggcaggag
    34441 accggctggt ggccggcgcg gtacggcgca gcggcccatg gcccgccgtg ctggccggga
    34501 ccgcggtcgt gggagcggcc ggcgagctgg ccgtcccgta cctgatcggc cgcaccgtgg
    34561 acaccctcgt gacgcgcggg ccggacgcca cccactggct cgcgctctgc gccgccgcgg
    34621 tcgccgccgt gatgctctgc gagagcatcg gcgtgtgggc gcgcggtgcc agcggcgccc
    34681 acgccgccgc gaccctgcgc accggcgtgc tgcggcacgt cctcggcacc ggctcggcgg
    34741 ccacccgccg cttcccggaa ggcgagctcg tcacccgggc cggcctgaac gccgaggagg
    34801 tcggccgggc gcccgagacg gtgaccagcg cgctggccct gctcgtgccc acggcgggcg
    34861 cgctggtcgc gctcaccctc atcgctcccg tcctgacgct gacgctcggg gcgggcatcg
    34921 tcgtcatcct cctcgtcctg cgtgccttcc tccgcgcgac gaccacgatc tcgggcggct
    34981 accaggaggt gcagggcgag atcgccgccc gcctcgtgga ggcgctgggc ggcgcccgca
    35041 cgatcgccgc cgccggcacg gcgggccgcg agtcgcgccg cgtgctcgcg ccgctgcccc
    35101 ggctgcgcgc gcacgggatg gggctgtggc gggccaacgc ctcggccgcc gtccggtcgg
    35161 ggctcgtcgt gccgctgctg gagatcgccg tgctcgccgc gggcggcttc atgctcgccg
    35221 ccggcgacct caccgtcgga gagctctact ccgccgcgcg ctacgccgtg ctcggggcct
    35281 cgctcagcac ggcgctgggc cacatcggcg gcctggccag ggcgcgcgcc gccgccggac
    35341 gggtggccga ggtgttcgac ctgccacccg tccggtacgg ctcccgcacg ctcccgcccg
    35401 ggccagggac gctccggttc cgcgacgtgg ccgtgaacgg gctgaccgtc ggcgacctga
    35461 cgttgcccgg cgggtccgtg acggccgtgg tcgggcggtc cgggtccggc aagtcgctgc
    35521 tggcggcgct ggccgggcgg ctggccgagc ccgaacgtgg aaccgtgctg ctcgacggcg
    35581 tccccctggg ggagctggcg gaggcggagc tgcggcgggc gatcggttac gccttcgaac
    35641 gcccggcgct ggtcggcgag acgatcggcg acgccatcgc cccggagccg gagcccgttc
    35701 cagagtttgc ggagccgccg gggcggcggg tcgtggaggc ggcgcgggcg gcgtgcgcgg
    35761 acgtgttcgt gcggcggctg ccgctcggct acgccacccc gctccgcgac gcgcccatgt
    35821 cgggcggcga gcggcagcgc atcggcctgg ccagggcgtt cgcgcagggg gagcggctgc
    35881 tcgtgctcga cgacgccacc tccagcctgg acaccgtgac cgagcgccag gtcggccggg
    35941 cgctcaccag cgacccgctc ggccgcaccc ggctcgtcgc cgcccaccgg ccggccaccg
    36001 ccgcccgcgc cgaccaggtc gtctggctcg acggcggcac ggtgcgcgcc tgcggcccgc
    36061 accacgtcct gtggcgggac ccggcctacc gggcggtctt ccagggagcc gagccatgaa
    36121 cccgcaggac tcgggagcgg cgtcatgaac ccgcaggaca cagggggccg cgtcgtgcac
    36181 ccgctcgccc acgcgttgcg gcgcgagccg cggcagctcg tccggctcgg gctctggtcg
    36241 gtggtcgagg cggcgcccgc gttcctcatc gggcaggccg tcgcccgcgc catcgaggac
    36301 gggttcgccg ccgccgcccc gatgatcggc ctcgcctggc tggccgcgct cggggtcgcg
    36361 tggctggccg gggcggtggc cgcgcggcag gtggtgctgg ccgtcgccgc cgtggcggag
    36421 ccgttccgtg acgacctgct gacgcgggtg gtggcgggcg cgctcaggac cggcacgggc
    36481 cgggacagcg ccgccgtggc cagggccggg ctccaggtgg agctggccag ggacgcgttc
    36541 gcggccgtgg tcaccaccgt acgggggttc gtgttcaccg taatcagcgt ggtgctgggg
    36601 ctgctgacgc tggcgcccga gacgctgctg ctggtcatgc cgcccttcct ggcggggctc
    36661 tgcctgttcc tggcctcgct gcccgcgctg gcccggcggc agcgcgcgta cctcgtggcc
    36721 gacgagcggc tggccgaggc catgacggag atggcaggcg ggctgcgcga catcgaggcg
    36781 tgcggcctgc gggacagcgt ggcggcgcgg ctcgaacgcc gggtcggcgc gcaggccgcc
    36841 gccgcgcgca ggctcgcccg ggtgagcgcc gtccgcaccg cggccctggc cgccggcggc
    36901 tggctgcccg tcgtgctcgt gctggcggga acgccgtggc tgatggagcg cggcgtgggc
    36961 gccggggtga tcgtgggcac cctcgcgtac gtcacccagt ccctcgcgcc cgcgctcggc
    37021 gggctcgtgc aggggctcgg cgtcagcggc gtgcggctgg ccgtctcgct cggacgcatc
    37081 ctcgccatgg ccccgccccc tgccctcgcc ccgccgctga tccgccccgc caccacggag
    37141 atccggctgg acgccgtcac cttcgcctac ggcccgcact ccgcgcccgt cgtggtcggc
    37201 ctcgacctgg tcgtccccga gggcgaccac ctggcgatcg tggggcccag cggggcgggc
    37261 aagtccacgc tcgcgtccct gatcagcggc ctgctgcggc ccggcaaggg cgaggtgctg
    37321 gtcggcgggg tgcccgccga ccgcctcgac cccgccgccc gcgtgctgat cccccaggag
    37381 gcgtacgtct tcaggggcac gctcagggag aacctgctgt accacgcacg aacggacacg
    37441 gggccggaca cggggccggc ggaagcgggg ccggcggacg ccgcgctgac ggacgccgcg
    37501 ctgacggacc ccacgctgac ggaccccacg ctgacggacg ccgcgctggc ggaggccgtg
    37561 gcggccgtcg gggcggaccg gctggtggac gagctgggcg gctacgacgc gcccgtcgag
    37621 cccggcgcgc tctcggccgg tcagcgccag ctcgtcgccc tggcccgcgc ctacctggcc
    37681 cctgccgccg tcgtcatcct cgacgaggcc acctgccacc tcgatcccgc cgcggaggcc
    37741 gtggccgagg ccgcgttcgc gcgccggggc ggcacgctga tcgtgatcgc ccaccgcctg
    37801 acctccgcgc tgcgcgcccg ccgcatcctc ctcatggacg gcacccggat cacgctcggc
    37861 acccacgagg agctggtccg gacctccccc ttgtacgccg acctggccgg ccactggcac
    37921 ccggagcccg tgtcatgaaa tttccagaca actacccgcc tgccgaacgc ctccccctca
    37981 ccgaccgccg ccacggccac gagatcgacg acccgtaccg ctggctggag gacccggtcg
    38041 accctcgcac ccgcgcctgg ctcgcggccc aggaccggct ctggcaggac gccgccgccc
    38101 gcctgccccg ccgcgagcgc ttcctcgcga ggctgaccga ggccagggag acgggcctgg
    38161 tgaccccgcc ggtgtggcgc ggcggccggc gcttccacct gcgccagtcg cccgaccagg
    38221 agcacccggt gctctgctgc gacgaccgcg tggtgctgga cccgatggag ctggacccgt
    38281 ccgggctgac gaccctggac gactggcagc ccgacctgga gggccgccgc ctggcgtacc
    38341 agacctcgcg cagcggcgac gagaaggcgt gcctgtacgt gcgggacctg gacacgggcg
    38401 cgatcgtgga cggccccatc ggcggctgcc gctactcggc ggtcgcctgg ctgccgggcg
    38461 gcgaggcgtt ctactacgtc cgtttccagc agggcgtctt cctgcacagg atcggctcgg
    38521 ccgaggccga cgtgcccgtg ttcaccaggg gcgcgatctc gtacggcgtg cagatcagcc
    38581 ccgacggccg gtggctgacg atctcggcgg gcaccgcgtc gggcaacggg ctctggctgg
    38641 ccgacctggc cggcgaagac ccggcgccgc gtcccgtaca ggacggctcg cacgcccgca
    38701 cggccggcgc ggtggcccgc gacggccgcc tgtacctgct caccgatcgg gacgccccgc
    38761 gccgccggct ctgcgtggcc gatccggagg cgcccgcggc ctggcgggag ctgatcccgg
    38821 aggacgggga ggcggtgctg ggggcgttca cgctgctgga cggggaccgg ctgctggtgt
    38881 cgaggacgcg gcacgcggtc ggcgagatcg ccgtgcacga cgcccgcacg ggggagcgga
    38941 tcggcatggt gccgctgccc ggcaacggct cgatcgcctc gctcacctcg cgccccgagg
    39001 gcggccccga ggcgtggttc gcctacacgg acgcggtcac gccggccgag atctggcgct
    39061 acgacgcccg tacggacgcc accacgcgct ggtccgccgc gcccggccga ggcacgccgc
    39121 cggaggtgcg cagccaccac gtcgagtacg cctccgccga cggcaccgtc atccgcatga
    39181 tcgtcgtcgc ccgcccttcg gcgggcggcc cgcgcccggc gatactcagc gggtacggcg
    39241 gcttcggcat ccccctcatg cccggctacg ccgccgactc cctggcctgg gtggaggcgg
    39301 gcggcgtgct ggccatcgcg aacctgcgcg gcggcggcga ggagggcgag ggctggcacc
    39361 gcgacggcat gcgggagcgc aagcagaacg tgttcgacga cttcgtggcg gcggcggaga
    39421 agctgatcgc cgacggctgg acgactccgg agcagctcgg catctggggc gagtcgaacg
    39481 gcggcctgct cgtcggcgcc gcgctcaccc atcggccgga cctgttcgcc gccgcggtgt
    39541 gctcggccgg gctgctcgac atggcccgct accacctcag cggcctcggc ccgtcgtgga
    39601 ccggcgagta cggcgacccg gacgaccccg agcagctcgg ctggctgctc gcctactcgc
    39661 cctaccacca cgtgcgcaag ggcgtcgact acccggcgac gctgttcacg gtcgcggcgg
    39721 ccgacacgcg cgtcgacccg atgcacgccc gcaagatgtg cgcggcgctg cagtgggcga
    39781 gcggcggcga ccggccggtc ctgctgcgct acgagccgga cgtggggcac ggggcgcggg
    39841 cggtcagccg ctcggtcgcg ctggccgccg acgtgctggc cttcttggcc gagcacaccg
    39901 gcctcgacct gccctgatca gatccagcct gactccctgg cgatgcggat cgcgtcgatc
    39961 ctgctgcgcg ccccgagctt ggccgtggtc ctggacaggt agttgcggac cgttccctcg
    40021 gcgaggtaga gcgaggccgc gatctccccg accgacgccc cgtcggcggc ggcgccgatc
    40081 acgtccagct cgcggggcgt cagcggcgcc tccgccggcc gcatggccgc gatcgccagc
    40141 tcggagtcga tgacccgctc gccctcggcg accctgcgga tgccgtcggc gagccgtccg
    40201 ggtggcgcgt ccttggccat gaatccgcgg acgtggacgt cgagtgcctt cttcagcagt
    40261 cccggcgtgc cgacgccggt gaggatgagc acgccgcact cgggtaattt ctcgtgcagc
    40321 tccccggcgg cggagagccc gtcctgcccc ggtaacgcga tgtcgatgac ggcgacgtcg
    40381 gggcggcagg cgcgggcggc ggccaggatg cggtcgccgc gttcgacctc ggccacgacc
    40441 tcgatgtcct cttcataggc cagcagcgcc acgagcgccc cacgtaccag gtgcatgtcc
    40501 tcagcgagca acgttcgaat caccatgcgt ccttgcggtc gacaggcttg caacgtctgc
    40561 gggctcctta atcctgccgt attgacccaa tcctgaaaag gacttgtatt tggtcgtcaa
    40621 ttgtttaccg gagaatgccc gtaccccgat gacggcctac caagcgtccg gccgtttggg
    40681 agatgctggc ggacatgaaa ccccgcgtgc ggccccttcc gcccgaacac tgggacgagt
    40741 tcacgaaggc ccatccgtac aacgtgttcg ccacgctggc ccgccatccc gccctctacc
    40801 ggggctggcg ggacttccac ggcgcgctgc aggacggcac gctgcccgcc agggaccggg
    40861 agctggccat cctgcgcacc gcccaccact gcgacagcgc ctacgagtgg gccaggcacg
    40921 cccgcctggc cctcgacgcg ggcctgaccc ggcaggaggt ggagctggtg cgccggccgg
    40981 acgccctgtg gtcggtcgag gaccagctcg tgctccaggt ggccgacgac ctctactatg
    41041 cgggcgacct gaccgacgcc acctgggcgg ccctgtgcga ccgctacgac gaggcgggcc
    41101 ggatcgagct ggtcatgctc gtggcccacc acgggatgct ggccctggtg ctgaggacgt
    41161 tcagggtgcg gccggagccg gagatcaccg aggagtgatc atcgtgacgc ccggcaccga
    41221 gccgatcgag gccagcgcct tgccggcgtc ggccagcccg atcgtgcggg tgaccagctg
    41281 atcgggatgc aggatcccgg ccctgatcat ctccagcatg ggcgggtagg cgtgcgcggc
    41341 catgccgtgg ctgcccagca gccgcagctc gtgggcgatc acgcggccca tcggcaccgg
    41401 cgtcgccccg cccggcagta ggcccacctg cacgtgccgg cccctgcggc gcaggctctc
    41461 gacggaggcg gcgcacgtgg cggggctgcc cagcgcgtcg atcgacacgt gcgcgccgcc
    41521 cctggtcagc tccctgacct gggccgccgc gtcaccatcg gagccgttga cgaagtgcgt
    41581 ggccccggcc agctccgcca ggtgcagcgc gtcgccgctg atgtcgacgg ccaccacgcg
    41641 ggcgcccgcc gccgtcgcga tcatcacggc cgacaggccg acgccgccgc agccgtgcac
    41701 ggccacccat tcgcccgggc gtacctcgcc gacctgcacc acggcgcgga acgcggtcgc
    41761 gaaccggcag ccgaggccgg ccgccgtggc gtaggccatg tcctcgggca cggcgatcag
    41821 gttgacgtcg gcgtggtcga tggcgacgta ctcggcgaac gagccccagt gtgtgaagcc
    41881 cggctgcgtc tgccgctcgc agacctgctg ctcgcccgtg gcgcaggcgg cacacgagcc
    41941 gcacgcgcag atgaacggca cggtcaccct cgcccccggc agccagccgc gcacgtcgga
    42001 gcccaccgcc tcgaccacgc ccgccagctc gtgccccggc acgtggggca gcaccttgat
    42061 gtcggggtcg tggccctgcc agccgtgcca gtcggagcgg cacaacccgg tcgcctcgac
    42121 tcggatcacc gcaccgtgcg gggcagggga aggatcgggc agctcgcgca cgtcgagctc
    42181 cccaccgaag atgtcaaagg caaccgctcg catctcatga gcttagggtg tgctgccgca
    42241 gctcgcgcaa ggcccggtgc gacggcgagc cgggctcggt ggtgtagagc accaggcgca
    42301 ggtcgtcgcg gtcgggcacc ggcatgacct ggcagatcgt gtcgatcgtg cccaccaccg
    42361 gatggtggat gcgcttgcgc tgctccctgc gtacctggac ctcgtgcctg ccccacagct
    42421 cggcgaactc ggggctgagc gcgagcagct cggccaccag cgcctggatc cgccggtcgc
    42481 cggggtagcg gccggcggcg gcgcgcaggt cggcgaccga ggcgcgggcg aaggcgccct
    42541 tctcctcgtc gtcgaagtgc agcctgatgt cgggcgacat gaagatccag cgcaggacgt
    42601 tgcgctggtc gggcgccagg cagtcgaggt tgcccatgat ggtggtcgcc atggggttcc
    42661 aggcccgcag gtcgtagcgg gcgtcgagca cgtaggcggg cacgtcgtcc aggaacgcga
    42721 tcaggtgcag catgctctgc ggcacgtcct ccctgatccg cggcgggtcc atgggctggc
    42781 cggccaggtg gaacaggtgg gcgcgctcgt cctggccgag catgagggcc ctggccaccg
    42841 cgttcagcac ctgcctggac gggtgcgggc cgcggccctg ctccagccgg atgtagtagt
    42901 cgatcgacat gcccgcgagc tgcgcgacct cctgccggcg caggcccggc gtgcggcggg
    42961 tgcccccggc gggcaggccc acgtccgcgg gggtgacccg ggcgcgcctg acccggagga
    43021 attcggcgag ttcgtcgcgg ttcatgcgtc catcctgggc cctggacgcg cccccgtggg
    43081 tggtaccgct gatcccagcc tctccaggtc tctcccgccg ccccgctgac cagcgcgaac
    43141 gtggaggcat gacgaacatc gcactcatca cgggcgccaa caagggcatc ggctacgaga
    43201 tcgccaggct gctggccggg cagggcgtca ccacgatcgt gggggcgcgc gacgaggagc
    43261 gcggccgggc cgccgccgag cggctcgggc agccgtacgt gcggctcgac gtgaccgacg
    43321 aggagagcgt ggccgccgcc gcgaagtgga tcgacggcga gtacggccgg ctcgacatcc
    43381 tcgtcaacaa cgccggcatc accggcgaca ccgccgccta cctgcccagc gccgccacgg
    43441 ccgcgcacct gcgggaggtc tacgagacga acgtgttcgg cgtcgtgacc gtgacgaacg
    43501 ccatgctgcc gctgctgcgc cgctcgccgg ccgggcggat cgtgaacatg tcgagcgagc
    43561 tcggctcgct ggccatggcg gcggacccgg acagcccgta cgccgacgtc aacatcctgg
    43621 cctacaactc ctccaagtcc gcgctcaaca tggtcaccgt ctcctacgcc aaggagctga
    43681 aggacacccc gatcaaggtg aacgccgcca accccggcta ctgcgccacc gacctcaacc
    43741 agcaccaggg attccgcacc gccgagcagg gcgcggccat cgccgtgcgg ctggcgacgc
    43801 tggacgaaag cggcccttct ggagcgttcc tggaggatgc gggcccggtt cgctggtgaa
    43861 ggtgtcaagg cttacttttg ggacagattg gggtgatggg aagagatctg gataaggagc
    43921 gatttaccga agcggagtac acccgcttcg gggagcgcat ccgggagcag ctcggagtgc
    43981 tccgcgagct gctcgacacc cccggcttcg ggcagggccc ggtcacgatc ggggccgagc
    44041 tggagctgtt cctgatcgac gacgagggcc gccccctgcc gcgcaacgac cgcgtacggg
    44101 acgccctcga cgacgaccgc gtggtgctgg agctgggccg ctacaacatc gaggcgaacc
    44161 tcaccccgct gcccctcgcg ggccggccct tcgaggccct gagcgccgag gtgcaggaga
    44221 tgatcgccaa ggtggacggg gccgtggagg gcggg
//
