LOCUS       NZ_CP020041            23050 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. 3211 isolate 3 plasmid p3211-2, complete sequence.
ACCESSION   NZ_CP020041
VERSION     NZ_CP020041.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. 3211
  ORGANISM  Streptomyces sp. 3211
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 240209)
  AUTHORS   Heinsch,S.C., Hsu,S., Hansen,L., Kinkel,L. and Smanski,M.J.
  TITLE     Complete genomes of three Streptomyces isolated from disease
            suppressive soils
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 240209)
  AUTHORS   Heinsch,S.C., Hsu,S., Hansen,L., Kinkel,L. and Smanski,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAR-2017) Biotechnology Institute, University of
            Minnesota, 1479 Gortner Ave, Saint Paul, MN 55108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-JAN-2017
            Assembly Method                   :: PacBio v. Jan-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:18:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,254
            CDSs (total)                      :: 8,154
            Genes (coding)                    :: 7,815
            CDSs (with protein)               :: 7,815
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 340
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 340
            Pseudo Genes (frameshifted)       :: 206 of 340
            Pseudo Genes (incomplete)         :: 257 of 340
            Pseudo Genes (internal stop)      :: 68 of 340
            Pseudo Genes (multiple problems)  :: 153 of 340
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:04:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 43349
            Orig. end                         :: 66399
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020041.1.
            Bacteria and source DNA available from Michael Smanski.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23050
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23050
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23050
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13050](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13050)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(651..863)
                     /locus_tag="B4U39_RS40120"
     CDS             complement(651..863)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS40120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_079408544.1"
                     /transl_table=11
                     /translation="MTRAQIAMDSAACLRVGGDPGAAEMAAAVYDLLPPAYRTGRVHSR
                     TQLLHRHLEGARAGCSATPSPDGAD"
     gene            complement(1027..1371)
                     /locus_tag="B4U39_RS45090"
     CDS             complement(1027..1371)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS45090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237297322.1"
                     /transl_table=11
                     /translation="MPSLTAGNTGRPGLLAYVNGLRFIEIEPFDTAAALSATELLHAGH
                     PWATVHAIHAARPSADFPASRYLLTLGDVGVAPVVAGLIAADGFHPASRPAVNARVWPP
                     WATFPDPAGR"
     gene            complement(1496..2575)
                     /locus_tag="B4U39_RS40130"
     CDS             complement(1496..2575)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998890.1"
                     /locus_tag="B4U39_RS40130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-oxoacid:ferredoxin oxidoreductase subunit beta"
                     /protein_id="WP_079408545.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-32, bitscore:
                     104.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEVTEATDGARTLLSLVPKAESKQSMKDFKSDQEVRWCPGCGDY
                     AVLAAVQGFMPELGLAKENIVFVSGIGCSSRFPYYMNTYGMHSIHGRAPAIATGLATSR
                     RDLSVWVVTGDGDALSIGGNHLIHALRRNVNLKILLFNNRIYGLTKGQYSPTSEVGKIT
                     KSTPMGSLDSPFNPVSLAIGAEASFVARTVDSDRKHLTEVLRRAADHQGTALVEIYQNC
                     NIFNDGAFEVLKDKDQALEAVIRLEDGQPIRFGADGTKGVVRNPATGDLEVVEVTAANE
                     AQILVHDARNASATTAFALSRLADPDTLHHTPIGVFRSVERPVYDTLMADQLDAAIDRS
                     GKGDLGALLTGNDTWTVVG"
     gene            complement(2568..4421)
                     /locus_tag="B4U39_RS40135"
     CDS             complement(2568..4421)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006347315.1"
                     /locus_tag="B4U39_RS40135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-oxoacid:acceptor oxidoreductase subunit alpha"
                     /protein_id="WP_107470314.1"
                     /transl_table=11
                     /translation="MKRIKPIDRVIIRFAGDSGDGMQLTGDRFTSETASFGNDLSTLPN
                     FPAEIRAPAGTLPGVSSFQLHFADHDILTPGDAPNVLVAMNPAALKANIADVPRGAEII
                     INTDEFTKRPMAKVGYATSPLEDGSLDAYNLHPVPLTTLTVEALKDFGLSRKEAERSKN
                     MFALGLLSWMYHRPTEGTESFLRQKFAKKPEIAEANIVAFRAGWNFGETTEDFAVSYEV
                     APATRAFPTGTYRNISGNLALSYGLVAASQQADLPLYLGSYPITPASDILHELSKHKNF
                     GVRTFQAEDEIAGIGAALGAAFGGALGVTTTSGPGVALKSEAIGLAVSLELPLLIVDIQ
                     RGGPSTGLPTKTEQADLLQAMFGRNGEAPVPIVAPRTPADCFDAALDAARIALTYRTPV
                     FLLSDGYLANGSEPWRIPEVADLPDLKVKFATGTNHTLGDGTEVFWPYKRDPETLARPW
                     AIPGTPGLEHRIGGIEKQDGSGNISYDPANHDLMVRTRQAKVDGIRVPDLEVDDPDGAT
                     TLVLGWGSTYGPITAAVRRLRGAGLPIAQAHLRHLNPFPRNLGEVLERYEKVVVPEMNL
                     GQLATLIRAKYLVDAQSYNQVNGMPFKAEQLATVLKEAIDD"
     misc_feature    complement(4398..4412)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            complement(4430..6391)
                     /gene="dxs"
                     /locus_tag="B4U39_RS40140"
     CDS             complement(4430..6391)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138575.1"
                     /locus_tag="B4U39_RS40140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_079408547.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.4e-97,
                     bitscore: 319.2, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-07, bitscore:
                     25.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISSRTTDFDSLHRGGPPGRVQNQTPLLHTLGGPRDLDALTPDQ
                     LVSLAQEVREFLVRTVTQTGGHLGANLGVVELTIALHRVFDSPRTPILFDTGHQSYVHK
                     LLTGRQDFSRLRARDGLSGYPSREESRHDFVENSHASAVLGWADGMARAKQLQGSGEHV
                     VAVVGDGALTGGMAWEALNNIAASPQRPLIIVVNDNGRSYAPTVGGLANHLAELRENRE
                     KVATWRDGPYRTPLVTEPETGDQRNGASSLPSNLFEALGLSYLGPVDGHDLTALESALR
                     NARTQGGAVVVHCVTRKGCGYAPAEECEEDRFHAIGVVHPATGIPVKTPHKDWTSIFAE
                     EMVALGHERREIVAITAAMLHPVGLSPFASQFPQRVFDVGLAEQHAVVMAAGLATAGLH
                     PIFAVYATFLNRAFDQVLMDVALHRIGVTFVLDRAGITGPDGPTHHGMWDLSILQAVPH
                     LRLAAPRDAEQLRKQLRESVAVDDAPTVVRYPKGAVGPIIAAAGQINGMDVLLGAPDSI
                     GTRPGMLRADVLLVSIGAMAPISLEAAAILAASGISSTVVDPRWVKPVNTQLPALAAEH
                     RMVVTIEDHGCVGGAGSMLAQAMREAAVSVTLHDFAIPQRFLDHSTREELMDDAGLTGP
                     AIACRIAALLAAQKEADR"
     misc_feature    complement(4685..4687)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6077..6079)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6624..6639
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     gene            complement(<6789..7892)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="B4U39_RS40145"
                     /pseudo=""
     CDS             complement(<6789..7892)
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127960.1"
                     /locus_tag="B4U39_RS40145"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTAISLGMPAVPTKLADRRVSRKIQVGKVAVGGDAQISVQSMTTT
                     RTSDIGATLQQIAELTASGCDIVRVACPTQDDADALAVIAKKSQIPVIADIHFQPKYVF
                     AAIDAGCAAVRVNPGNIKQFDDKVKEIAKAANETRTPIRIGVNAGSLDARLLKKYGKAT
                     PEALVESALWEASLFEEHGFGDIKISVKHNDPVVMVNAYRQLAAACDYPLHLGVTEAGP
                     AFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPAEEVKVGIQILESLNLKPRRLEIVSCP
                     SCGRAQVDVYKLAEEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIF
                     VKGEVIKTVPESKIVETLIEEAMKIAEQ"
     misc_feature    complement(8327..8342)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.44"
                     /tool="antismash"
     gene            complement(8688..9935)
                     /locus_tag="B4U39_RS40150"
     CDS             complement(8688..9935)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="B4U39_RS40150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_079408548.1"
                     /sec_met_domain="p450 (E-value: 1.5e-27, bitscore: 90.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSCKRLFSFDPDLIRHPQPAYEELHANPSLYRDEVTGSFVVSRY
                     DEVVQVLQDSDTFSSRQALSPQLGEFINSLSAELPPERLDSLLLLQQILLCKDGADHRR
                     LRKLINRAFTPSVVNHLKPRISENCDTLINEISDGETLNFTDRFAKPFTIGVIAGILGV
                     PLKDYSKFREWTTAIITLVNGDPISENVLTAYMDSAAEFMEYFSVRSRELLAEPDSSLL
                     SEITRIHHNDKNSLVTDIVGSCISLLVAGHETTVHLLCGSVLELARNPKIVRRIEEDME
                     SLVPKFLNEILRLQSPVQGLFRTATRNAVIGGELIPKGSSVLVLYGAANRDPDKFPNAD
                     EISLHRDSRPGNLAFGFGRHVCLGSALALAEGQIAVSAWIGRFPRSVLAEPADRISYYR
                     HLLLRGPRSLAITAHA"
     misc_feature    complement(8835..8837)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8991..8993)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9441..9443)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9911..9924)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.89"
                     /tool="antismash"
     misc_feature    9981..9994
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.97"
                     /tool="antismash"
     misc_feature    complement(9982..9995)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    complement(9982..9996)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.24"
                     /tool="antismash"
     misc_feature    complement(9989..10003)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.18"
                     /tool="antismash"
     gene            complement(10001..11215)
                     /locus_tag="B4U39_RS40155"
     CDS             complement(10001..11215)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="B4U39_RS40155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_159395868.1"
                     /sec_met_domain="T2TS (E-value: 4.7e-46, bitscore: 151.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDAIMSLFGAEPELPDRTAFETEGLHIWALIQVTSLKLIIYRAL
                     GRGNEISGDDIDLLISTQKGHEIWEGNILIHLSVLNALAGLPATEEVVARGVDKVLRHQ
                     RVDGGFPFVTDTDTWCTATGGLALAAAGANEGDLHRIARHLVRQQRSNGGWAYTDIAQQ
                     TDVDDTSVAVEFMHSLDARRYKTSINAGLDFLRSVRHDQGGFPTYVRSAAPEACMTAAA
                     VNALGVDAVRNAQALQEGIRFLAAAQKPDGGFEPDWSASALHTVFRVVLATGQQVPRTS
                     AVSSHIRARALTLVHISQNGDGGWGWGPDAASDAVSSSYALIALCSQSAVEPAVRAAEY
                     ILSCQKEDGSIASRSDSIGPRPFIFRIPVLADIFAMLALGHLASRLAPTIGISEGPTIL
                     EERGT"
     misc_feature    complement(10958..10960)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10967..10969)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10976..10978)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10985..10987)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11039..11041)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11354..11370)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.76"
                     /tool="antismash"
     misc_feature    complement(11659..11675)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(11673..11693)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.01"
                     /tool="antismash"
     misc_feature    11844..11853
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            complement(12013..13050)
                     /locus_tag="B4U39_RS43215"
     CDS             complement(12013..13050)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="B4U39_RS43215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_159395869.1"
                     /sec_met_domain="T1TS (E-value: 4.1e-58, bitscore: 191.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFEIDERTVSWMHSFSLGGNGKERERMAHCRIGQLVSRMVPDGH
                     PGGLQIFADFLTWIFTFDDEYCDEGPLGSRPGELADAVSPMLRAFESPESPIEDSADRY
                     SHALRDLRRRLDVYATSAQIEYLSGALGGYLLSEVRKAGYVAAGRQPRSLDSYIPMRMQ
                     NGGALAIIAFPPIVRGYEVPLSLLQTNRVRAITEMCVTISNYDADIFSYAKERVRSGDG
                     FNIIDVICREYGCNEEEAFVLAKNMRDRIMGLFLRISDCLPLQGIRNLDRYAAGLNRYM
                     RGVIDWHFETDRYIYLDGIKGSKKIVQPVGWDDSLDGLPHDPLPVCSISWWWSYDPSGC
                     TRATT"
     misc_feature    complement(12322..12324)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12499..12501)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12643..12645)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12658..12660)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12718..12720)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13091..13104
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.66"
                     /tool="antismash"
     gene            complement(13863..14507)
                     /locus_tag="B4U39_RS40160"
     CDS             complement(13863..14507)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014349350.1"
                     /locus_tag="B4U39_RS40160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="WP_079408550.1"
                     /transl_table=11
                     /translation="MRLYLSSWRTGDHPDQFLALLDRPGPVAVIANAVDALPVDERRVA
                     LEREIDALASLGLQPVELDLRDYFDQPPEQVAAALAGFPAVWVRGGNVFVLRHALARSA
                     ADRALAALLREDAIVYAGYSAGACVLAPDLHGLDRCDDPNAVTVAYDAPPRFDGLAVID
                     YVVVPHIDSPGHPESEILTAVARYYRVHGIAYRPLRDGQAIVIQGKAIRVH"
     gene            complement(<14614..15098)
                     /locus_tag="B4U39_RS40165"
                     /pseudo=""
     CDS             complement(<14614..15098)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007261717.1"
                     /locus_tag="B4U39_RS40165"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS110 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDVFCGTTGRRDTTTSRSSTALVSCWPSAASATIWRAIRSCWTCW
                     LITVTRRVSDPSGDRDQPQAAGRHVAAECPPDLRGQSDGGLPLSRPSRREPQRSPTPVT
                     PSCSPTSSARTC"
     misc_feature    complement(15050..15065)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     gene            complement(15965..17426)
                     /gene="ltrA"
                     /locus_tag="B4U39_RS40175"
                     /pseudo=""
     CDS             complement(15965..17426)
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ltrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007513513.1"
                     /locus_tag="B4U39_RS40175"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="group II intron reverse transcriptase/maturase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPKDAPSNGGALLDEAPVGPRQRVSEMQAKLHRWAATDHGRRFDD
                     LFNLVHDPATLRLAFDRVAGESRGPDCQRRWPDGHRRGGADRGPEVPGRPSGPAQSGFV
                     QGTSGAGEADCQAGRVREGAAAGDSHDRRPGRPGCAEAGAGTDLRGRLQAGLVRVPTQE
                     AGTGRDCRDPPLRHQGLPLGAGRGHRGVLRRDRSRRTDGPGQEEDQGQAGPVLGEGVPE
                     SRDPHGTRRAPGHPNRDTTRGHPVPTACQHRSVSARRAPARAMGRQRGAVRRFEAPDPT
                     PQRPADMANRPLRG"
     gene            complement(17998..18126)
                     /locus_tag="B4U39_RS45435"
     CDS             complement(17998..18126)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS45435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_257789890.1"
                     /transl_table=11
                     /translation="MEGDRSRTGAGFDTLDLTVDLLVTPDLTRWEWKDEDLRREAL"
     gene            18494..19012
                     /locus_tag="B4U39_RS40180"
     CDS             18494..19012
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS40180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159395870.1"
                     /transl_table=11
                     /translation="MKVTIDTASDSHEEAIRAVRTAYGKPQPEPDGRPVVLPEDVVWRP
                     PGSYEHPWTEEMLRTWVKALHTVEELDLVWRVCTEPGLRGGGHRGVRVAAPDRQAGYTA
                     MGLVSQRLNAAARELWAWQMPFVIDEARRTRTVDRQVAAILLDALAGYSLWPRLRHHTD
                     PPALTTQRS"
     misc_feature    19151..19160
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.31"
                     /tool="antismash"
     misc_feature    complement(19209..19223)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.12"
                     /tool="antismash"
     gene            19264..19974
                     /locus_tag="B4U39_RS42245"
     CDS             19264..19974
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS42245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_107470315.1"
                     /transl_table=11
                     /translation="MEIRKIPQERRRIVRAGMVLAVLAGLASAGWCVYAWQSAPIAGAS
                     RTGGVDAASRMAKAETERRLEGIVDVLPGAPRPLGVAAADHCLRSSSFEGESPGPLSCQ
                     WRLERFVVFDGDLRTVGDAWGKALSGDRWIGSHAPFPVGYSSTSERYAYSDPRTHDRLS
                     ITIIQDGRDLRLLHDANRFDFEGVEEYERERRDFTGRTAAERAVAQGQQVASVSLVRAY
                     YSQSGNAPFEPMHW"
     gene            <20133..20528
                     /locus_tag="B4U39_RS43860"
                     /pseudo=""
     CDS             <20133..20528
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612313.1"
                     /locus_tag="B4U39_RS43860"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS701 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RWALARRSIRKPDEIAYHLAYAPLETTVKELVQIAGTRWAIEECF
                     QTAKNECGLDQYEVRCYVGWYRHITRAMLAHAFLTSTAREAQEKKGGGTDEAARAIEFT
                     VAELGDSWQLVASGPHTFAAAEDGTTR"
     gene            complement(<20806..21087)
                     /locus_tag="B4U39_RS42255"
                     /pseudo=""
     CDS             complement(<20806..21087)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008744985.1"
                     /locus_tag="B4U39_RS42255"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVGKGSRAAIISDRRVTGLSGEVIAELGVEVGLLWHERHQVRLES
                     RPRKRAVGAGAMHRLVFVDGLLAALVHLRHGATHDVLACWFGVDRSTIT"
     gene            21205..>21315
                     /locus_tag="B4U39_RS45100"
                     /pseudo=""
     CDS             21205..>21315
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558180.1"
                     /locus_tag="B4U39_RS45100"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRGDLTNAEWDRLGSLLPTGGARGGRWSDHRRLIGG"
     misc_feature    21253..21255
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    21256..21258
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21522..22682
                     /locus_tag="B4U39_RS40205"
     CDS             21522..22682
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735974.1"
                     /locus_tag="B4U39_RS40205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS701 family transposase"
                     /protein_id="WP_079408648.1"
                     /transl_table=11
                     /translation="MGGERVDARSWAGELKALQERFAHRFSRLEPRESALACMQGLIAP
                     LERKNGWTLAEEAGHGGPDRIHRLLNRIDWNADEVLDDVRDYVIEHLGDPEAVLIVDDT
                     GFLKKGVRSAGVQRQYSGTAGRTENSQIGVFLAYASPHGRTLIDRRLYLPTSWTDDRER
                     CRAAGIDDTVAFETKVVTAKAMVRRAFADRVPFRWVTADAAYGFSKGWRTELERADVFH
                     VMATMRHDTVVTRWAMDRPVHDLFPGLARQKWKRRSCGDGAHGPRVYDWARVEVKPWHR
                     EDRRHWVIARRSIRRPEEISYYIAYCPAETTLDELISVAGSRWAVEECFQTAKQECGLD
                     DYQVRRYDGWHRHMTLAMAAHACLTVLRAREADTGKAETDPPSSYP"
ORIGIN
        1 cggcggcggc ttggatggtg tcgctcatgt gttcgcggcg gccgaggtgg cgggcgagtg
       61 cccgtcagtt cttgatatgt gcgatgccgt gctcgacccg gatccggcgt gaggagtgcg
      121 ccttgcgccg gcgctcgtag atctcctcgt accagtccgc tgggttcttc ttgactttgc
      181 ggtgtggtgg tgtcgacgcg gccgctggcg ccgaggtggt ttatgacttc ggcgagggtg
      241 cggagccgga tgccgggtgc gatggtgcag ccgcgggttg cgagcagggg ccacacctcg
      301 ccgatggccc gggtgatcgt ggaccggtcg acaccgaacc agcaggccag aacgtcatgc
      361 gtggcaccgt ggcggaggtg gacgggcgtg gccaggagcc ggtcgacaaa gaccagccgg
      421 tgcattgcgc cagcgccaac ggcccgcttg cgtggcctgg acagtctcac ctggtgccgt
      481 tcatccatgc cataacggac cgacctcggc gatgagttcg gcgatcacct cggccgacag
      541 acctgtgatc cgccgatcgc tgatgatcgc tgcacgagac ccgttcccca ccacacaaac
      601 atgatcaggg atcagcccca acgccgcacc gccaaccatg cacgaactcg ttagtcggcc
      661 ccatcaggcg agggcgtcgc cgagcagcca gcgcgggcgc cctccaggtg ccggtggagc
      721 agctgggtgc gggagtgcac ccggccggtc cggtaggcgg gcggcagcag gtcgtagacg
      781 gcggcggcca tttcggcggc gcctggatcc ccgccgaccc gcaggcacgc ggcggagtcc
      841 atggcgatct gcgcgcgggt catcaccgaa ggcgaggacg tcagggccaa ggcgtcgtcc
      901 tgtacccggt aaagcggcgc aggagcgtgt acacctgaga ggtgcacgtg atgcctctgg
      961 gccaggtccc cgaaaggtgt tcgccagctc aggactgtcc aactgctcgg caagtgcgga
     1021 cgtcgttcac cgcccggcgg gatccgggaa ggtcgcccag ggcggccaga cacgggcgtt
     1081 aacggctggc cgcgaggcag gatggaatcc gtcagctgca atcagaccgg cgaccaccgg
     1141 tgctacgccg acatcgccca aagtgagcag gtagcggctg gccgggaagt ctgccgacgg
     1201 gcgggccgcg tggatggcgt ggacggtggc ccaggggtgc ccggcgtgca ggagctcggt
     1261 ggcagacagg gcggcggccg tgtcgaaggg ctcgatctca atgaaccgca gcccgttgac
     1321 gtaggcgagc aggccgggcc gcccggtatt acccgcggtc agggagggca ccggcgcgta
     1381 gagggtgccc aggcggccgt aggcacccgt ccggaataac ccaactccac gtaccccgcc
     1441 ccataccgac atcaacgacg cctcaccaca taggacacgg tctaacgcaa ggccgctacc
     1501 cgacgacggt ccaggtgtcg ttgccggtca gcagcgcccc gaggtcgccc ttgccgctgc
     1561 ggtcgatggc cgcgtcgagc tggtcggcca tgagggtgtc gtagacgggc cgctcgacac
     1621 tgcggaacac cccgatcggg gtgtggtgga gggtgtccgg gtcggccagg cgcgagagcg
     1681 cgaacgcggt ggtggcgctg gcgttccgcg cgtcgtgcac caggatctgc gcctcgttgg
     1741 cggcggtcac ctcgacgacc tccaggtccc ccgtggcggg gttgcgcaca acacccttcg
     1801 tgccgtccgc gccgaagcgg atcggctgcc cgtcctccag ccggatcacg gcctccaggg
     1861 cctggtcctt gtccttgagg acctcgaagg cgccgtcgtt gaagatgttg cagttctggt
     1921 agatctccac cagcgccgtg ccctggtggt cggccgcccg gcgcaggacc tcggtgaggt
     1981 gcttgcggtc ggagtcgacg gtgcgggcga cgaaggaggc ctcggcgccg atcgccagcg
     2041 acaccgggtt gaagggcgag tccagcgagc ccatcggcgt cgacttggtg atcttgccga
     2101 cctcggaggt gggggagtac tggcccttgg tcagcccgta gatccggttg ttgaacagca
     2161 ggatcttgag gttgacgttg cggcggaggg cgtggatgag gtggttgccg ccgatggaga
     2221 gcgcgtcccc gtcgcccgtg acgacccaga cggacaggtc gcggcgggag gtggccaggc
     2281 cggtggcgat ggccggggcg cggccgtgga tcgagtgcat cccgtacgtg ttcatgtagt
     2341 acgggaagcg ggaggagcag ccgatgcccg agacgaagac gatgttctcc ttcgcgaggc
     2401 cgagttcggg catgaagccc tgaacggcgg ccagtacggc gtagtcaccg cacccggggc
     2461 accagcggac ctcctggtcc gacttgaagt ccttcatcga ctgcttgctc tcggccttcg
     2521 gtaccagcga gagcagggtc cgtgccccgt cggtcgcctc cgtcacctca gtcatcgatg
     2581 gcctccttga gaaccgtggc gagctgctcc gccttgaacg gcattccgtt gacctggttg
     2641 tacgactggg cgtcgaccag gtatttcgcc cggatcaggg tggcgagctg cccgaggttc
     2701 atctccggca ccactacctt ctcgtaacgc tccaggacct cgccgagatt cctcgggaag
     2761 gggttgaggt ggcgcaggtg ggcctgggcg atggggagtc cggcgccgcg cagccggcgg
     2821 acggccgcgg tgatggggcc gtaggtggaa ccccagccca ggaccagggt ggtggcgccg
     2881 tccgggtcgt ccacctcgag gtcgggcacc cggatgccgt cgaccttggc ctgccgggtg
     2941 cggaccatga ggtcgtggtt ggcggggtcg tacgagatgt tgccgctgcc gtcctgcttc
     3001 tcgatgccgc cgatgcggtg ttcgagaccg ggggtgccgg ggatggccca ggggcgcgcg
     3061 agggtctccg gatcccgctt gtagggccag aacacctcgg tgccgtcgcc gagggtgtgg
     3121 ttcgtgccgg tggcgaactt gaccttcagg tcgggcaggt cggcgacctc cgggatccgc
     3181 cagggctccg acccgttggc gaggtagccg tcggagagca ggaagaccgg ggtccggtag
     3241 gtgagcgcga tccgggccgc gtcgagggcg gcgtcgaagc agtccgcggg ggtccgcggc
     3301 gccacgatcg gcacgggagc ctcgccgttg cggccgaaca tggcctgaag caggtccgcc
     3361 tgctccgtct tcgtcggcag gccggtggag ggaccgccgc gctggatgtc cacgatcagc
     3421 agcggcagct ccagcgacac cgcgaggccg atcgcctccg acttgagcgc cacaccgggc
     3481 ccggaagtgg tggtcacccc gagcgcgccg ccgaaggccg cgccgagcgc cgcgccgatg
     3541 ccggcgatct cgtcctcggc ctggaaggtc cgcacgccga agttcttgtg cttcgacagc
     3601 tcgtgcagga tgtccgaggc gggggtgatc gggtaggagc ccaggtagag gggcagatcc
     3661 gcctgctggc tcgcggcgac gagaccgtag gagagcgcca ggttcccgga gatgttgcgg
     3721 taggtgccgg tcgggaaggc ccgggtggcg ggggcgacct cgtaggagac cgcgaagtcc
     3781 tcggtcgtct ccccgaagtt ccagccggcg cggaacgcga cgatgttcgc ctcggcgatc
     3841 tccggcttct tcgcgaactt ctgccgcagg aagctctccg tgccctcggt gggccggtgg
     3901 tacatccacg acagcaggcc cagcgcgaac atgttcttgc tgcgctcggc ctccttgcgg
     3961 gagaggccga agtccttcag cgcctcgacc gtcagcgtgg tcagcggtac cgggtgcagg
     4021 ttgtaggcgt cgagcgagcc gtcctccagc ggcgaggtcg cgtagccgac cttggccatc
     4081 gggcgcttgg tgaactcatc cgtgttgatg atgatctccg cgccgcgcgg cacgtccgcg
     4141 atgttcgcct tgagggccgc cgggttcatc gcgaccagca cgttcggggc gtcgcccggc
     4201 gtgaggatgt cgtggtcggc gaagtggagc tggaaggagg agacgcccgg gagggttccg
     4261 gcaggggcgc ggatctcggc ggggaagttc ggcaacgtcg acaggtcgtt cccgaacgac
     4321 gccgtctccg aggtgaaccg gtcaccggtg agctgcatac cgtcaccgga gtcacccgcg
     4381 aaccggatga tcacacgatc gatgggcttg atccgtttca tgggatgcgt caacggtcgg
     4441 cttccttctg cgctgccagc agtgcagcga tgcggcaggc gatggcgggg cccgtcaggc
     4501 ccgcgtcgtc catgagctct tcacgtgtgc tgtggtccag gaatcgctgg gggatggcga
     4561 agtcgtgcaa cgtcacgcta acggctgcct cgcgcatggc ctgggcgagc atggagccgg
     4621 cccctccgac gcagccatga tcttcgatgg tgacgaccat gcggtgttcc gctgcgagtg
     4681 cgggtaattg tgtgtttacc ggcttgaccc agcgggggtc gaccactgtg ctgctgatgc
     4741 cacttgcagc gagaatggcg gcggcttcta gactaatcgg cgccatggcg ccgatggaga
     4801 cgagtagaac gtcggcgcgc agcatgccgg gtcgggtgcc gatgctatcg ggagctccga
     4861 ggagcacgtc catgccgttg atctgaccag cagcggcaat aataggacct acagcaccct
     4921 tggggtaacg cacaaccgtt ggggcgtcgt cgacagcgac tgactccctg agttgcttgc
     4981 gcaactgctc cgcgtcgcgc ggtgcggcga ggcgtaggtg ggggacggcc tggaggatgg
     5041 acaagtccca cattccgtgg tgcgtgggtc cgtcggggcc ggttatacca gctcggtcca
     5101 aaacgaacgt gacgccgatt cggtggagcg ctacgtccat gaggacttgg tcgaacgctc
     5161 ggttgagaaa ggttgcatat actgcgaaaa tagggtgcaa ccctgctgtt gccaggcctg
     5221 ctgccatgac gaccgcgtgt tgttccgcaa gaccgacgtc gaagacgcgt tgcggaaact
     5281 gactcgcaaa gggggaaagt ccgacagggt ggagcatcgc cgcggtgatg gccactatct
     5341 ccctgcgctc gtgaccgagg gcgaccattt cctcagcgaa gatcgacgtc cagtctttat
     5401 ggggagtttt aacaggaata cctgtagccg gatggacgac gcctatggcg tgaaagcgat
     5461 cctcttcgca ctcttcggcg ggggcgtagc cgcagccctt tcgagtgacg cagtggacga
     5521 caacagcgcc tccctgggtt cgggcgttgc gcagggcaga ctcgagtgcg gtcaagtcat
     5581 gtccgtcgac agggccgagg tagctgaggc ccaaggcttc aaacaggtta cttggaagcg
     5641 acgaggctcc gttgcgctga tcaccagtct cgggctcagt tacaagcggg gttcgatacg
     5701 gcccatcgcg ccacgttgct actttctcgc ggttctcgcg cagttcggca aggtgattcg
     5761 cgaggccgcc gacggtcggt gcgtaggagc gcccattgtc gttcacgacg ataatcagcg
     5821 gtcgttgcgg ggaagcggcg atattgttca gtgcttccca agccatgccg cctgtcagcg
     5881 caccatcgcc gacaacggca accacgtgtt ccccagatcc ttggagttgc ttcgccctgg
     5941 ccatgccgtc ggcccaaccc aggacggcgg aggcgtgtga gttttccaca aaatcatgcc
     6001 gggactcttc gcgtgaaggg tagccggata gcccgtctct ggcgcgcaag cgagaaaaat
     6061 cctgacggcc ggtcaataat ttgtgtacat aactttgatg tccagtgtcg aagaggatgg
     6121 gagtacgggg ggagtcgaat actcggtgca aagcgatggt gagctcgacc acaccaaggt
     6181 tagcgcccag gtggccgcct gtctgtgtca cggtgcggac caggaattcc cgcacttcct
     6241 gtgccaggga tacgagttgg tcgggggtta gtgcgtccag gtcccgcggg ccgccgagcg
     6301 tatgcaaaag tggcgtctga ttctggaccc tacccggcgg accgccgcga tgtagggagt
     6361 cgaagtcggt ggtgcggcta ctgatcgcca tgctggtcct cgtcacttgt tccgaacgac
     6421 gatatggtgg gcaagaattg atagagctgt cgcgtaccgc agcctgagcc gacccacatc
     6481 aggtacggca ggagctggct gcggcgtggt gacgacgggt cgttctggcg tagccgcgac
     6541 cgtcggcctc ctcgaaagtg cagcgtggag cgaacggatc agccaaaggg cgtcgactgt
     6601 ccggacggga agcgcacact gcggtcacgc ggcggtttca ctcaagctcc agcggagttc
     6661 tctggtgtct tcgactggcc acacggccga gggatggtgt cgctgcgtgc cgctccacca
     6721 cgcggatcac atggagcacc ctggcggcag ccatcggccg gggcggccgg aaccctcgca
     6781 gcctgcgtct gctcggcgat cttcatcgcc tcttcgatga gggtctccac gatcttcgac
     6841 tcggggacgg tcttgatgac ctcgcccttc acgaagatct ggcccttgcc gttgccggag
     6901 gcgacgccga ggtcggcctc acgggcctcg ccggggccgt tgacgacgca gcccatgacc
     6961 gcgacgcgca gcgggacctc catgccctcc aggcccgccg tgacctcctc ggccagcttg
     7021 tagacgtcga cctgggcgcg gccgcaggag gggcaggaga cgatctccag gcggcgcggc
     7081 ttgaggttca gcgattccag gatctggatg ccgaccttga cctcctccgc cggcggggcg
     7141 gagagggaga cgcggatggt gtcgccgatg ccctcggaga gcagcgcgcc gaaggcgacg
     7201 gcggacttga tggtgccctg gaaggcgggg ccggcctcgg tgacgcccag gtgcagcggg
     7261 tagtcgcagg cggcggcgag ctggcggtag gcgttgacca tgacgaccgg gtcgttgtgc
     7321 ttgaccgaga tcttgatgtc gccgaagccg tgctcctcga agagggaggc ctcccagagc
     7381 gcggactcga ccagcgcctc gggggtggcc ttgccgtact tcttcaggag tcgggcgtcg
     7441 agggagccgg cgttcacacc gatgcggatc ggggtgcgcg tctcgttcgc ggccttcgcg
     7501 atctccttga ccttgtcgtc gaactgcttg atgttgcccg ggttcacccg gaccgcggcg
     7561 cagccggcgt cgatcgcggc gaacacgtac ttcggctgga agtggatgtc ggcgatgacc
     7621 gggatctgcg acttcttcgc gatcacggcg agtgcgtcgg cgtcgtcctg ggtcgggcag
     7681 gccacacgga cgatgtcgca gccggaggcg gtcagctcgg cgatctgctg gagcgtcgcc
     7741 ccgatgtcgg aggtcctggt ggtggtcatc gactgcacgg agatctgtgc gtcgccgccg
     7801 acggccacct tgccgacctg gatcttgcgg ctgaccctgc ggtcggcaag cttcgtcggc
     7861 acggccggca ttccgagaga gatggcagtc acttgttttc ctcctcctgc ggcgcaccca
     7921 atccgggact catcctgccc gcctttcctg ggttcacttc gggtgcgcga atcacctaag
     7981 agctgcgagt cgacaggcaa ggtggcgctc ctgtcctcat ctctggaaac cgggcaggtc
     8041 ctgccccaag acgctcttcg ccgagagccc cgccgccgag gcccctgcat ccgccctggc
     8101 cccgccgatg cttcccggcc ggtcgaatcg ccctcccccg tggcgctcac ggtgttccga
     8161 accccccgct gcggagccac gtccaccaga cgaactgcaa tggaatccgg catgaggtca
     8221 gcagcttcct gctggatcgg ggcggccctg cgcgctgaga gcctgacagt acctccttca
     8281 gacaccccct cactctcgtc gacgtggata actccgcctt ccagtctgtt caccacaagc
     8341 gtgttgagga cgcgctgttt ttgcatgtag cgggatccgc ccgactgctc aatcacggtc
     8401 ggggcacact tcacagttgc gccacatccc ttagatgcag ctaaccagaa cctccggcac
     8461 gcaacacctc tcggcgctag gttcctggag ggtagacgga accgagttct tttggcgccg
     8521 ctcatcatcg ggaactcctc gcgcatcatg ccacctacgt gacaatcccc cacgaaatat
     8581 cgaaaagcct cagtaagcca ttctatcgct tccagaacca gccacaccta gaccacccaa
     8641 tggagaggaa accgcgccgg cattgagcca ttttcccagc tgttgatcta cgcatgagca
     8701 gttatggcga gtgatcgggg gccgcgcagg aggaggtggc ggtaatagga aatgcgatca
     8761 gctggctccg caagcacgct gcgtgggaat cgaccgatcc acgcgcttac ggcgatctgc
     8821 ccttccgcga gagctaaggc cgagccgagg cacacgtgcc gaccgaaccc gaaagctaga
     8881 tttcctggac gcgaatcacg gtgaagggaa atttcatccg cgttcggaaa tttatcagga
     8941 tccctgttcg cggcaccata caagaccaaa actgacgacc ctttcgggat taattcgccg
     9001 ccaattaccg catttcgggt cgcagtccga aacaatcctt ggacggggga ttgaagcctc
     9061 aaaatctcgt tcaggaactt cggaacgaga gattccatgt cttcttcgat tctgcggaca
     9121 atcttggggt tccttgcgag ttccagaacc gatccgcaca gcaggtgcac tgtagtttcg
     9181 tgacctgcga ccaacaagct gatacaactc cccacaatat ccgtcaccaa ggagttctta
     9241 tcattatgat gaatccgcgt gatttcggaa agcaagctgc tgtcgggttc cgcaagcaac
     9301 tccctggatc gcacactgaa gtactccata aactccgcgg cgctatccat gtacgccgtc
     9361 aaaacatttt ccgatatcgg atcgccgttg accaatgtta tgatcgcagt ggtccattcg
     9421 cgaaatttcg aataatcctt taatggaact ccaaggatgc ctgcaattac gcctatagta
     9481 aaaggttttg cgaatctatc ggtgaaatta agagtttcac cgtcggagat ttcgttgatt
     9541 agagtgtcgc agttttccga gattctcggt ttcaagtggt ttaccacgga aggcgtaaat
     9601 gcgcggttga tgagtttgcg cagccttcgg tgatcggcgc catctttgca aagcagtatc
     9661 tgctgcagga gaagaagcga gtcaaggcgc tccgggggca gttctgcaga aagggagttt
     9721 ataaactcac ccagctgggg gctgagggct tgcctagagg aaaacgtgtc agaatcctgc
     9781 aggacttgca cgacctcatc gtagcgcgat actacgaagg atccagttac ttcatctcga
     9841 taaagagatg ggttggcgtg aagttcttca taggcgggct gtgggtggcg aataaggtcg
     9901 ggatcaaacg aaaacagccg tttacaagac ttcatctcga ctccgcaaca ctgtagaact
     9961 cgaaggcgga cctaaccagc aatttatatg aaaatgatag ttaggtgcct cgctcctcaa
    10021 gtatggtggg tccttcggaa attcctatag tgggtgctag gcgactggcg aggtgcccga
    10081 gtgcgagcat ggcgaagata tccgccagta ccgggatccg aaatatgaat ggcctgggac
    10141 caatcgagtc cgaacgcgat gcaatagatc catcttcttt ttggcatgac agtatgtatt
    10201 cggctgctcg cacggccggc tcaacggcac tctggctaca cagagctatc agggcgtaag
    10261 agctgctaac ggcatcactt gccgcatccg ggccccagcc ccagcctccg tcgccgtttt
    10321 gagagatatg cacgagtgta agcgctcggg cgcggatatg gctgctcaca gccgatgttc
    10381 gaggcacctg ctgtccagtg gccaaaacca cgcggaagac agtatggagc gcactcgcac
    10441 tccagtccgg ctcgaatcca ccatccggct tttgcgcagc cgcaaggaat cgaatgcctt
    10501 cctgaagagc ttgcgcgttg cgtacggcgt cgactcccag tgcgtttacg gcggctgctg
    10561 tcatgcaggc ttctggggct gcgctccgca cgtaggtggg aaacccaccc tggtcgtgcc
    10621 gtacgctgcg caggaaatcc aagccagcat taattgaggt cttgtatcgc ctagcatcca
    10681 acgaatgcat aaattctaca gcgactgagg tgtcatcgac atcagtttgc tgagcgatat
    10741 ctgtgtacgc ccagccacca ttgctgcgct gttgtcgaac caggtgcctc gcgatccggt
    10801 gcaggtctcc ctcattggct cctgcagccg caagagcgag cccgcccgta gcggtacacc
    10861 aagtgtcggt gtcggtaaca aagggaaatc caccgtcaac tctttgatgc cgcaaaacct
    10921 tgtcgacacc gcgcgcgact acttcctcag tagccggtaa tccagctaaa gcatttaaaa
    10981 ccgataagtg aataagaatg ttcccctccc atatttcatg tcccttttgc gtggatatta
    11041 aaagatcaat atcatcacca cttatctcgt tgccacggcc gagcgcacga tagatgatca
    11101 acttaaggga tgtgacttga atcaaagccc agatgtgaag accttctgtt tcgaaagcag
    11161 tccgatcggg cagctccggc tctgccccga acaaggacat aatcgcgtcg accattgctt
    11221 ttttcctggc tccagtgaag gccggagcct tcgctaggag tcggtccaat acgaacgaac
    11281 ctgcattgac tgtccgatcg agcgcggcgg agacaatcag acggtcaagt gaatccccca
    11341 acgcgcggcg ggattgtagg aaatgaacaa ggttgacacg agctcgaggt tcttgtccga
    11401 cgtattctag gagacgtaga cacaaagccg attccaaaac tcggctatcg caagggtcgc
    11461 gtatagctcc cgatggctca attttttctg tcagatgaga tctcagtgcc agagtcgcct
    11521 cggtgatatt cccggggaac agatgccgtg gccacgcctg aatgtgagaa taccggtcag
    11581 agactctcat atcccaatcc acttctattt ctctggagcc gctcctactg aaatttatct
    11641 tttagtgcag cagtgcgaag tgaacaaaat tacatattgc aggtgtaata tcttgtctcg
    11701 ttacttcaca caccctaaaa atctccacca ctccgaaacc tgcaaaatga caaatttgag
    11761 cgattgcatg tgcattctgc gagctttccg cccggtgaga gtggtgtagg tattttcgca
    11821 ttccgggtac tgcggcgctg gcgtgttgtt tgacaacgcg cggatgagtg tttgaggtct
    11881 tcctgtacgc atactactga tcctctttct ggcgctagat gtggcctagt attcgtaata
    11941 accgtttagg gccgaggaca ggatcaccct cgctgcggct cttggattca gccaaaggaa
    12001 agttcgtaaa gatcaggtag tggctcgcgt acacccgctg gggtcgtaac tccaccacca
    12061 tgatatggag caaactggga gcgggtcatg tggcaggccg tcaagagagt cgtcccaacc
    12121 tactggctga actatttttt tgctgccttt aatcccatcc aggtaaatat atcgatccgt
    12181 ttcgaagtgc cagtcgatta caccccgcat ataacgattc aagcctgccg catatcgatc
    12241 cagatttcga attccttgca gtggcaaaca gtcggatatt ctgaggaaca gtcccatgat
    12301 tcgatctctc atgttttttg ctaaaacaaa tgcctcctct tcgttacagc cgtactcgcg
    12361 gcaaattaca tcgatgatgt tgaatccatc gccgctccgg actctctctt tggcgtaaga
    12421 gaaaatatcg gcatcgtagt tggagatcgt cacacacatc tccgtgatcg ctctgactct
    12481 attggtctgc agcagcgata atggcacctc gtacccccgc acgataggcg ggaacgcgat
    12541 tatggcgaga gctcccccgt tctgcatacg cattggtatg taactgtcca gagagcgcgg
    12601 ttgtcggcct gctgctacat aacctgcctt tcgaacttcc gataacaggt atccgcctaa
    12661 agcccccgag agatattcta tctgtgctga tgtcgcgtaa acgtctagac gtcttcgtaa
    12721 atctcgcagt gcgtgactat atcgatcggc ggagtcttct atcggggatt cgggcgactc
    12781 gaaggcacgc agcatggggg acacagcatc cgccagttcc cctggtcgac tgccgagcgg
    12841 tccttcatcg caatattcat cgtcgaatgt gaaaatccat gtcaggaaat cggcaaagat
    12901 ctgcaatccg cccggatgcc cgtccggaac catgcgacta accaattgcc caatccggca
    12961 gtgcgccatt ctttcccgct ctttgccatt cccgcccagg ctgaacgagt gcatccagga
    13021 aacagtacgc tcgtctattt cgaaagccat ggggtgaaca gcagggtcga gtgaatgata
    13081 gtatggcgga attttagaaa tagacatggc gtcctatagt tcttagcggg tggaagatca
    13141 cccgacaact ggctgaacag cggtcattgg agcaagtgcg ggataatcca acgggattat
    13201 gggtgcccgg gtggtcgacc caatacccgc agccatgctc cgtttcaaaa cgggtgctgt
    13261 ccctgcttcg ccgatgcagc ttgcatgtat atatacgacc tattagggtg ttttggttca
    13321 ctctgcgcaa gtcgcgtcgc ggcccgcccg cgacggatac gggccctgga tctgtctccc
    13381 accgctttcc gcaggtgagc gggatgccag cgacgcgggc cgatgcatgc cgtcgcgcag
    13441 ttggccgtcg gtctcgcggg cgcctgctgc tgcagttcgt cgagaagctg cccgggcgcg
    13501 gccgcacgga cagtgcggcg tcggcgaacg gtccttcggc gaagccgttg cgtacggaca
    13561 ggccgggctc gatgaaggtc atcgtgtcgg tcctctccgc ccggccgcac gtggtctccg
    13621 ggtggagacg cggtcgcgaa acggagcgac gggaacgtag agcaccgaga tcgccggcgt
    13681 cacgtcgtgg ccgctggccc cgggcagtga agagggcctc taccccacgg gtaagacacc
    13741 tcatgcagtt aagccgtcaa gcgaagctgc ggctgcggcc atctggatca gttggagccg
    13801 gggctgttac cactgcaagt ggtagaggcg catcagcaga accatcagtc acatcatcac
    13861 tattagtgga cgcggatggc tttcccttgg atcacgatgg cctgcccgtc acgaaggggg
    13921 cggtaggcaa ttccatgcac acggtagtac cgggcaaccg ctgttaggat ctcggactcg
    13981 ggatgccctg gtgagtcgat gtgcggcacc acgacgtagt cgataacggc cagaccgtcg
    14041 aagcgcggcg gggcgtcgta ggcgacggtg acggcgttcg gatcgtcgca ccggtccagt
    14101 ccgtgcaggt caggggcgag gacacaggcg ccagcgctgt agccagcata gacgatagcg
    14161 tcctctcgca agagcgcggc cagggctctg tctgccgcgc tgcgggccag cgcgtgacgt
    14221 aggacgaaca cgttgcctcc acggacccag accgccggga agcccgcaag agccgcggcg
    14281 acctgctcgg gcggctggtc gaagtagtcg cgcagatcga gttcaaccgg ctgcaaaccg
    14341 agtgaggcga gcgcgtcgat ctcgcgctcg agcgccacgc gtcgctcgtc aacgggcaag
    14401 gcatcgacgg cgttggcgat cacggcaact ggaccgggtc tgtccagcag ggccaggaac
    14461 tggtccggat ggtcgccggt ccgccaggag gagagataca ggcgcacact tcatcatgcc
    14521 cgaccagtcc ggcaccttga cagcccatcc agagacgaca gagcgacgaa ccccgctggc
    14581 aggccaacgc cgaggccgct gcgggtcgac gcccggaaag tattcgcgca gtagcgagcg
    14641 gagctggttg cagacctgct gccggttcca gaccgcgtcc tactgtgctc gggccaggac
    14701 agccaccgcc tgggccagtt cggtgtcggc ggccagcggc cgatgcatca gcatgtccgt
    14761 gcggatgatg ttggcgagca tgagggcgtc accggggtcg gacttctttg cggctcacgc
    14821 cgtgacggtc gcgatagcgg gaggccgcca tcggattgac cgcgaagatc tggcgggcac
    14881 tctgccgcaa cgtggcgacc agcagcctgc ggctggtctc gatcgccact gggatcggag
    14941 actcgacgtg tcaccgtgat cagccagcag gtccagcaag acctgatagc cctccagatc
    15001 gtcgccgatg cggcacttgg ccagcagctt accagtgccg tcgatgaccg tgacgtcgtg
    15061 gtgtccctcc gccctgtcgt cccgcagaac acgtccatgg atcctgcccc ttcgccggtg
    15121 ctgttctcga acgcgagcac gcggagccgc acggcgcact aattccagga ctccaaggtc
    15181 cgccacctca tcagccgtgc gcggcaccgc caggccgcac gggcgcacgc cgtgtccaga
    15241 gctcgaagct cgtgaggaag aacgcgtcac cgtgcggcgg ctcatccatt aagggtcccg
    15301 aacctgacgg gcccgtgggg gcagaacgtg cgaggaccgg ccggcgccca gcgccaccag
    15361 tctttaccaa gacctcgcgc ggtcggaggt gtcgtagggg tcaccacggc accgaccgga
    15421 ccacacacgt cctgccccag gctggaaaag tgccgccccg ggcccctcag agatccagaa
    15481 cctctcatta ctaacgaatt agaggtgtcg tcggcgcgga caggcttgcc cacggggtct
    15541 gaacagggac aacgggcggt gtccgattcg ccgggctccc cctcccggtc acaccttcgg
    15601 tcccccgccg caagcaaccc tccaggcaac tgttcagccc ccttccggtg caacctctcc
    15661 gcggctgccg taggccgagg aaggcacggc gtgggccagg ccggctccca cctccagccc
    15721 gcccaccgct ccgcctgcgc gaaggccccg gagcgttcgg cgagcatcgc cagaacctca
    15781 ccgcgggcgg cgtctacggc ccggtgctcg gcgtcggagg caatgccaag ccgccgcacg
    15841 tgcgcgtact cgcagagtaa gcccggggcg cggtggcagg gtcgcccctg ctccgtctcc
    15901 ccggacttct cgccgaaccc gccgtgcacc tctcagcgca acgggctctc cacggcatct
    15961 gccgtcaggc tggttgtgtc catgggttgg ggatcttgtt gccgcggtat cgggtgaccg
    16021 ggatgtcccc gatcctccgc aacctgatgg cgcccgccgt gatcggctgc cacgtcccgg
    16081 agggagtgat cagccgccgt ccgacgtctc cgaggctcca gtcgtgccgc gagcgcatca
    16141 tgcgcacgac tctccaccag gtgaaacgcg tccaccatgg cgaagacccg tttcgcgacc
    16201 gcgtatttga agtactcggc ccatccgtgc gtgatcatgt tcagcctggt cagcacgtac
    16261 tccatgtcct gttgcgacaa cctgcgggtc atggcacgga ccttcatctt gatcgagcgc
    16321 acagcgcgcc gggagatgtc ggtgcagacg taccacttgt tcgtccctcg tttgcggcgc
    16381 cactggatgt ggaacccagg aagtcgaacc cctcgctcag gtgcacgatc cgcgtcttgg
    16441 ctgatgacag ccgcaacccg atccgtacga gcacctgagc gatctcgtcg cgcaacgccg
    16501 ctgtgtcctc ctcggtcccg tggaccatga ccgcgaaatc atccgcgtag cggacgattc
    16561 gccatgtcgg caggcctttg cggcgtcggg tctggcgctt cgaaccggcg gacagcaccc
    16621 cgttgccttc ccatggctcg tgcaggtgct cgtcgagcac tgacagagcg atgttggcaa
    16681 gcagtgggga caggatgccc ccttgtggtg tcccggttcg ggtgtcctgg tgctcgccga
    16741 gttccgtgag gatcccggct ttcaggaacg ccttcaccaa ggacaggacc cgcttgtcct
    16801 tgatcctctt cctgacccgg tccatcagtg cgacgtgatc gatctcgtcg aagcacgcct
    16861 cgatgtccgc gtccagcacc cagcggtagc ccttggtgcc gaagtggtgg atctcggcaa
    16921 tcgcgtcctg tgcccgcctc ctgggtcgga acccgtacga gaccggcttg aagtcggcct
    16981 cgaagatcgg ttccagcacc agcttcagcg cagcctggac gacccggtcg gcgatcgtgg
    17041 gaatccccag ccgccgcacc ttcccggacc cgcccggctt ggcaatctgc ttctcccgca
    17101 ccggaagtgc cctgaacgaa cccactttga gctgggcccg aaggtcgtcc aggaacctca
    17161 ggaccccgat ctgctcctcc acgtcggtga ccgtcaggcc atcgacgctg gcagtccggg
    17221 ccccttgatt cccccgcgac ccggtcgaac gccaacctca gcgtcgccgg gtcgtgcacg
    17281 aggttgaaca ggtcgtcgaa ccggcggcca tggtcggtcg ccgcccaacg gtgaagtttg
    17341 gcctgcatct ccgatacccg ctgccgtggc cccaccggag cctcgtccag cagagcgccg
    17401 ccattcgatg gtgcgtcttt cggcattgca acctcctccc ctctcgatat cgctgccgcc
    17461 cttccccatg tgccgggctc tctcccccgc tcggggtact acggcggctc cgccccatca
    17521 ggccattcgg cagtcgatgc gcctatcccc tccgaagcgg ctggctgccg ccccgcgggg
    17581 aactgcacct ggtggttccc gtgttcactg tgattcgctc gatggagtgg gagcccgact
    17641 gtgtccccgc ggcatcgcca tgagtacgcc gcaggctttc ctcatggcct ccgggtcggc
    17701 aaagacagac ctccccagga gttccgacca cccggccatg gatgatcgtg cgcaccgcat
    17761 ccggcccata tccgccaggt tggagccggt ggaagagtgg gggacgtaac gacgccagtt
    17821 cttcacgtac tcctctccgt cacgttcgcc gggccacacc atctggcagt gctggcgcgt
    17881 cccgtctttg tcagggctgc tcccgccctc cccggcatca cccggatcgg gctgccctca
    17941 gcttcaccgt cctgctgcga caggatcagt ggcgcaggtc tttcacctcc gctcgaatca
    18001 cagcgcctca cggcgcaagt cctcgtcctt ccactcccag cgggtgaggt cgggcgtgac
    18061 caacaggtcc acggtgaggt cgagggtgtc gaacccagcc ccggtgcggg accggtcccc
    18121 ctccacgcct gcgcaataca gggcgggcca gcgggcctgc gctcgggcgc gcaggcggtc
    18181 acgaagcccg cgccggtgtc ggcgacaacc cgcagtgcct gctcgctcca cacccggctc
    18241 gaccggtgca cgtcacgccg tacgaccgtc tggcccgtct cgataccgcg caccgcgtct
    18301 tcctccggtc ggggccttgg actgtccggc ccggcttgcc caactcagcc caccccggcc
    18361 ggggtgggca agccgccgtc cgggggtggc ttgcccaggg tctccttggg cttgcccact
    18421 cccccggaac accccgttgc ggcagtgcgc gccgggtagc ctggcacagt gcgttgagct
    18481 tagggggtgg gcgttgaagg tcacgatcga caccgcgtcc gactctcacg aggaggcgat
    18541 ccgtgcggtg cgcacggctt acgggaagcc acagcctgaa cccgatgggc ggccggtggt
    18601 gctgccggag gacgtggtgt ggaggccgcc gggcagctac gagcaccctt ggacggagga
    18661 gatgctgcgg acctgggtga aggcgctgca caccgtggag gagctggatc tggtctggcg
    18721 ggtgtgcaca gagcccggcc tgcggggggg tggtcatcgc ggagtacgtg tcgccgcacc
    18781 tgaccggcaa gccggctata ccgcgatggg tctggtcagc cagcgcctga atgcggccgc
    18841 acgtgagctc tgggcgtggc agatgccctt cgtgatcgac gaggcgaggc ggacccgcac
    18901 cgtggaccgg caggtcgccg cgatcctgct cgatgccctg gccggatact ctctgtggcc
    18961 ccggctgcgc caccacaccg acccgcccgc gctcaccacg cagcggtcct gaacccggat
    19021 acgcgcacct gggcaagcct cccgggagca tggcttgccc aggtaaggct tgggcttgcc
    19081 caaccggtga ccggtcaccg gcgtcaggct gtacgactca aggggtccga atgcccgctg
    19141 gccgcctgat cgatttttga gtgctgaata ctctattcgt cggaccctga ttatgatccc
    19201 tttctgtcaa atttcggaca gattcgtagc tgttcggtga cgtgggcttg ggaggatctc
    19261 ggcatggaaa tcaggaagat accccaggag cggcgccgga tagtccgtgc gggaatggtg
    19321 ctggctgtgc tggcgggcct cgcctcggcg gggtggtgtg tctacgcgtg gcagtcggct
    19381 ccgatagctg gcgcttcgcg gaccggtggg gtggacgcgg cgagccgcat ggccaaggcg
    19441 gaaaccgaac gccggctcga ggggatcgtc gacgtcctgc cgggggcacc gcgaccgctc
    19501 ggtgttgcgg ctgcggacca ctgccttcgt agttcctcct tcgaaggcga atcgcctggt
    19561 ccgctgagct gccagtggcg actggagcgg tttgtcgtct tcgatggcga cttgcggacg
    19621 gttggtgatg catggggaaa ggcccttagc ggtgaccggt ggatcggctc acacgcgccc
    19681 ttccctgtcg gctacagctc tacttctgaa cggtacgcgt acagcgatcc ccgaacccac
    19741 gaccgtctca gcatcacgat aattcaagat ggtcgcgatc tacgtctcct gcatgatgcg
    19801 aaccgtttcg acttcgaggg tgtcgaggag tacgaacgag agcggcggga tttcaccggg
    19861 cgaacggccg cggagcgcgc agtggcacaa gggcagcagg tcgccagcgt ctcgctggta
    19921 cgcgcctact acagccagag tggcaacgct cctttcgaac ctatgcactg gtgacaacct
    19981 gatcgaggtg ccgtcgaacg gccagtcggg acggcggccg cctgcgagct gccgccgtat
    20041 cgtgctgagg gtcctcgcgt ctaccactgg gcggcgatga ggctgctggc cgtcgaggag
    20101 ttcgactacc agggcgaggc ccccaccgga ggcgttgggc actggctcgc cgcagcatcc
    20161 gcaaacccga cgagatcgcc taccacctcg cctacgcgcc cttggagacc accgttaagg
    20221 agctggtgca gatcgcggga acgcgctggg cgatcgagga atgcttccag accgcgaaga
    20281 acgagtgcgg cctggaccag tacgaagtcc gttgctacgt cggctggtac cggcacatca
    20341 cccgcgccat gctcgcccac gccttcctga cctccacggc acgtgaggcc caagaaaaaa
    20401 aggggggtgg taccgatgag gcagcacggg caatcgagtt cacagtggcg gagttgggcg
    20461 actcctggca gcttgtcgcc tccggccccc acaccttcgc ggcagccgag gacggcacca
    20521 cacgctgagc gggtcgaaat ggcgccgcca gcggcaggca gtcgtccgcc gctgcgccgc
    20581 gctgccgcat gatcgacgga cagcccgacg aagaccaccc ctgaccacac cgcagcccgc
    20641 tacactccac ccgcccagta aaacccgcag gtcagacacc aaaatcctgc tggagtatca
    20701 ggttctgttc ttcgttgcga tcactgcgtt ggtgggggct tctgatccag atggttgccg
    20761 cgcgaaggtg gagtccggcg gggtagctcg ggggttctgt cgtaccgtga tcgtggagcg
    20821 gtcgacgccg aaccagcagg ccagcacgtc atgcgtggca ccgtggcgaa ggtggacgag
    20881 cgcggccagg agcccgtcga caaagaccag ccggtgcatt gccccggcgc caacggcccg
    20941 tttccgtggc ctggactcca gtctcacctg gtgccgttca tgccacaaca gaccgacctc
    21001 cacgccgagt tcggctatca cctcgcccga cagacctgtg acccgccgat cgctgatgat
    21061 cgctgcacga gaccccttcc ccaccacaca aacatgatca gggatcaagc cccaacgccg
    21121 cacctcccaa ccatgcacga ggtcgttagg cactgcttct tggacctcct gacgtgactg
    21181 gggtgttggg gtcacgctgt ctgtatgggt cgtggagatc tgacgaatgc ggagtgggat
    21241 cgactggggt cgttattacc tactggtggt gcccgcgggg gccggtggag tgatcaccgc
    21301 cggttgattg gtggcgcgtt cgacggcggc gcggagggtg ttgaccgagt ggctggcctc
    21361 cttgttgcct gcggactggt cccgccgggt ggtttgcgtc ggcgggcacg tactccggtg
    21421 ccgatgcagc cgaggtctcc gagcttgtct cggtcggcga acgcctagta ctgcaacggt
    21481 gttttccgtg actgttgggc aggtcggtcg ttggtgtggt tatgggtggg gaacgtgttg
    21541 atgctcggtc gtgggctggt gaactgaagg ccttgcagga gcggttcgcg caccgcttct
    21601 ccaggttgga gccgagggag tcggctcttg cctgtatgca ggggctgata gctccgctgg
    21661 agcggaagaa cgggtggacg ctcgcggagg aggccgggca cggcggcccg gaccggatcc
    21721 accggttgct gaaccggatc gactggaacg cggacgaggt cctggacgac gtgcgggatt
    21781 acgtcatcga gcacctcggc gatccggagg cggtgctgat cgtggacgac accgggttcc
    21841 tgaagaaggg tgtccgctcg gccggcgtcc agcgccagta ctccggaact gccgggcgga
    21901 cggagaactc ccagatcggg gtgttcctcg cctatgcctc tcctcacggc cgcacgttga
    21961 tcgaccgccg actgtatctg cccacgtcat ggacggatga ccgggaacgg tgccgggccg
    22021 ccggtatcga cgacacagtc gccttcgaga cgaaagtcgt caccgcgaag gccatggtcc
    22081 gcagggcctt cgcggacagg gttccgttcc ggtgggtgac cgcggacgcc gcttacggct
    22141 tctccaaagg ctggcggacc gagctggaac gggccgatgt cttccacgtc atggccacca
    22201 tgcggcatga caccgtcgtc acccgctggg ccatggaccg ccccgtccac gacctgtttc
    22261 ccggccttgc gaggcagaag tggaagcgcc gttcctgcgg tgacggcgcc cacggcccga
    22321 gggtctacga ctgggcgagg gtcgaggtga agccctggca ccgagaggac cgccggcact
    22381 gggtgatcgc ccgccgaagc atccgccggc ccgaggagat ctcctactac atcgcctact
    22441 gcccggccga gaccacactc gacgagctca tctctgtcgc cgggagcaga tgggcggtcg
    22501 aggaatgctt ccagaccgcg aagcaggagt gcggtctgga cgattaccag gtccgccgct
    22561 acgacggctg gcaccgccac atgaccctgg ccatggccgc ccacgcctgc ctcaccgtcc
    22621 tgcgagcccg cgaagcggac acagggaaag cagaaacgga tcctcccagc tcatacccct
    22681 gaccctcccc gaactccgac gcctgatcca ccgcctcgcc caccgccgcc cggcacccac
    22741 cgaccacgtc ctgcactggt cacactggcg acggcgacgg caattccaag cccgcatcag
    22801 ccactacaaa cgacgcggcc acacaccacc cgaagctgcc aaccagtcag actaaagacc
    22861 gttgcagtac taggccgttt cttagggatc acctcgcggt ccagatgtga atggccgcga
    22921 ggtggagggc cgcccggtag accgttgccg tcttgtcgta gcgggtggcc aggccgcgcc
    22981 actgcttgag cttgttgatg catcgctcga cggtgttccg ctgcttgtag gcggccttgt
    23041 cgaaggccgg
//
