LOCUS       NZ_CP020040            21095 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence.
ACCESSION   NZ_CP020040
VERSION     NZ_CP020040.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. 3211
  ORGANISM  Streptomyces sp. 3211
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 518852)
  AUTHORS   Heinsch,S.C., Hsu,S., Hansen,L., Kinkel,L. and Smanski,M.J.
  TITLE     Complete genomes of three Streptomyces isolated from disease
            suppressive soils
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 518852)
  AUTHORS   Heinsch,S.C., Hsu,S., Hansen,L., Kinkel,L. and Smanski,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAR-2017) Biotechnology Institute, University of
            Minnesota, 1479 Gortner Ave, Saint Paul, MN 55108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-JAN-2017
            Assembly Method                   :: PacBio v. Jan-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:18:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,254
            CDSs (total)                      :: 8,154
            Genes (coding)                    :: 7,815
            CDSs (with protein)               :: 7,815
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 340
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 340
            Pseudo Genes (frameshifted)       :: 206 of 340
            Pseudo Genes (incomplete)         :: 257 of 340
            Pseudo Genes (internal stop)      :: 68 of 340
            Pseudo Genes (multiple problems)  :: 153 of 340
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:04:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 484902
            Orig. end                         :: 505997
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020040.1.
            Bacteria and source DNA available from Michael Smanski.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21095
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21095
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21095
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11095](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11095
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    131..146
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            194..700
                     /locus_tag="B4U39_RS39720"
     CDS             194..700
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="B4U39_RS39720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_159395850.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.5e-21, bitscore:
                     70.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATSTVAAAGNNLPYGQDLANKTVDMSSPNDSTPISRMITSECKH
                     IPAELPGVVAVSAIEADNRKSAWSNYGDNRIHVTAPGAGVYSTVPGGGYEEHIGTSVAA
                     PHVSGVAALLLSRNPGMSPGDLRSALAGQADNLPCHDQCTGTTEKNSYFGEGRVNAYRA
                     VGGQN"
     gene            830..>1278
                     /locus_tag="B4U39_RS45035"
                     /pseudo=""
     CDS             830..>1278
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477291.1"
                     /locus_tag="B4U39_RS45035"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGLGWYPWRAVLDVPHALVEWVETHRHPRG"
     gene            1448..1645
                     /locus_tag="B4U39_RS45040"
     CDS             1448..1645
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS45040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237297316.1"
                     /transl_table=11
                     /translation="MEDEDKGEAAAPVSDNEMVDEVVERLLDNADASGAALLGEGGLLT
                     EITKAVLERALEAEMNEHLG"
     gene            1951..>2158
                     /locus_tag="B4U39_RS45045"
                     /pseudo=""
     CDS             1951..>2158
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /locus_tag="B4U39_RS45045"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTWQNRPLDQGWPIIYIDALWVKICFGSVTSKPVYLAVGVDSDGR
                     KDLLGLWVGWRGRHHMDGGPVRAA"
     gene            2226..2393
                     /locus_tag="B4U39_RS45050"
     CDS             2226..2393
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS45050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237297317.1"
                     /transl_table=11
                     /translation="MTAPKATVQICVILPIRASLRLSSSKDHSKLVPAIKAIDTARRSA
                     EQALGLFGAC"
     gene            3519..3716
                     /locus_tag="B4U39_RS43160"
     CDS             3519..3716
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS43160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159395851.1"
                     /transl_table=11
                     /translation="MTDDKHAHPRNSKGERICRQCLDPDKPLRESLGRKPVIHCSKLCT
                     RRAYEERRRQKKAAASVPMR"
     gene            4498..6054
                     /gene="istA"
                     /locus_tag="B4U39_RS39730"
     CDS             4498..6054
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="istA"
                     /gene_functions="other (smcogs) SMCOG1213: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123889.1"
                     /locus_tag="B4U39_RS39730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS21 family transposase"
                     /protein_id="WP_237297313.1"
                     /transl_table=11
                     /translation="MSLRALMRKYGVGYETVQKALISAMPEPRKKMEPRETRLDPYKPV
                     IDGILTADLTAPRKQRHTVKRIYDRLLDEHGADISYQMVRGYVAARRQEIRLEAGKGVV
                     DAFVPQTHRPGAEAEVDFGDVTVKLAGELVTCYLFAFRMSYSGKAVHRIFASAGQEAFF
                     EGHVHALNVLGGVPTGKVRYDNLRAAVAQVLGLSRRRVEAERWTAFRSHYGLEAFYCQP
                     GIRGAHEKGGVEGQIGWFRRNHLVPVPEVDTLADLNAVIDRWDQEDDNRRIRSRTHTIG
                     EYFATEQPLLAPLPEDPFETGRLSTPRVDRYSQICVRMNRYSVPVRLIGRTVRVMLHAS
                     ELVVYDGREEVARHERLIARGATRLELDHYLEALIRKPGALPGATTLDQARAAGRFTPI
                     HDAWWQASVKAHGERDGTRALIEVLLLSRHLPHEHLVTGLAAALQSGALTSDAVALEAR
                     KAADADTEPDETPPPAPGSQNGHAPLPAAVRARLPPDKRPLPSVAHYDQLLRLRRPDHN
                     T"
     gene            6065..6859
                     /gene="istB"
                     /locus_tag="B4U39_RS39735"
     CDS             6065..6859
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="istB"
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008734492.1"
                     /locus_tag="B4U39_RS39735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="WP_079408452.1"
                     /transl_table=11
                     /translation="MTLPRQRGLTEQAANTAVDQACRMLRLPTIRSQFPELAEKAEREQ
                     MSYLGFLAELLLAECDDRARRRSERRIKAAGFPRDKSLRKFDFDANPNLDAAMIHTLAK
                     CEWIKKGLPLCLIGDSGTGKSHLLIALGTEAAMAGYRVKYVLVTKLVNELVEAADEKQL
                     TKTIARYGRVDLLCIDELGYMELDRRGAELLFQVLTEREEKNSVAIASNESFSGWTKTF
                     TDPRLCAAIVDRLTFGGNIIETGTDSYRLATTRARAEQQSIS"
     gene            complement(6925..7260)
                     /locus_tag="B4U39_RS39740"
     CDS             complement(6925..7260)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007451670.1"
                     /locus_tag="B4U39_RS39740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_335755653.1"
                     /transl_table=11
                     /translation="MTSASALSDLGLWLGELSVFDATAEAVPFLWDLAVTDSVASRADV
                     IQLLRTILEQANPPRLDVQYAAHRAVLDGRSLADRLASDRDVAVQAAAQRLVAAIDNHV
                     CEACCPA"
     misc_feature    complement(7431..7445)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.7"
                     /tool="antismash"
     gene            8008..8598
                     /locus_tag="B4U39_RS39745"
     CDS             8008..8598
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS39745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_079408454.1"
                     /transl_table=11
                     /translation="MAGRPARISAFEAASRAVVLRDAGLSAGDIAEISGISVTLVRRLL
                     RLPADQQPPIHRTTAEAVLGVPFAGLSGRRRHPGLVPSDTSATLLQELSVRGWPTSFLA
                     NRLGTSTQTLTAIRARKRPRISLTLDQTIQNCHRELTAGTPAEYGIAAHRSRRANAAAR
                     QRAQNLLPPHQATFNRPSPLTRPKPAIGQRSMQ"
     misc_feature    9993..10007
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.23"
                     /tool="antismash"
     gene            10001..11095
                     /locus_tag="B4U39_RS43165"
     CDS             10001..11095
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="B4U39_RS43165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_159395852.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-57, bitscore: 190.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFISENSTCYHPLEPAIHPMAAEIDERAVSWMHSFGLGANNEARE
                     RMVHYRVGQLASRIVPDGHHEGLQIFADFLTWIFALDDEYCDEGMLGSKPGELADAVSR
                     MLCAFESPESLIEDPADRYSHALRDLRLRLETCATSSQIGYLSGTLGGYLLSEVRKAGY
                     VSAGRHPRSLDSYVPMLMQNGGTLAMIAFPPIVQGYEVPLSLLQSHPARAVTEMCATIA
                     NCDSDILSYSKGWIRSGHGFNTIDVICREYHCSEQAAFIAVKGMRDQIMELFLRMFQHL
                     SSHGVPNLDRYMAGLHRYMRGVIDWHSETDRYVHSGRVKEDCEISEKSEWGDPVSVLQC
                     DPLLTQATAWWWRYDPYRRPEADI"
     misc_feature    10005..10019
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.03"
                     /tool="antismash"
     gene            complement(12035..12857)
                     /locus_tag="B4U39_RS42160"
                     /pseudo=""
     CDS             complement(12035..12857)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009332786.1"
                     /locus_tag="B4U39_RS42160"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRGRWSWVVPDGLWEIAGPLIPPSKVRSQGGGTQDTPDETLFAA
                     IIYVLVSGCAPGGRCRRASGYRSRRLTAGS"
     gene            <12980..13537
                     /locus_tag="B4U39_RS39760"
                     /pseudo=""
     CDS             <12980..13537
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984222.1"
                     /locus_tag="B4U39_RS39760"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RDAEPSACVIDAQSVKTSTSVPAASQGIDAGKKIAGRKRSIITDT
                     LGLLLTVLVTAANVQDSVAGTRLIDQVAAEHPTVRKVWVDGGYRQHLVEHAATLGIDME
                     ISARKPGTRGFTPIPKRWAVERTYGWLMLHRRLARDYETLPGRSEALVNLAMTDLMARR
                     ITGENTISWRDPTEQTKQPILG"
     misc_feature    complement(13587..13600)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.73"
                     /tool="antismash"
     gene            13837..14292
                     /locus_tag="B4U39_RS39770"
     CDS             13837..14292
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010041889.1"
                     /locus_tag="B4U39_RS39770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ASCH domain-containing protein"
                     /protein_id="WP_079408456.1"
                     /transl_table=11
                     /translation="MTTDATPPVNLASMPRAEFAFPGPLRDQLVAAILNGSKTSTTGLL
                     VDYELEGEPLPKVGSRSVVIDSDDRPVAVIEITGVRVVPLAQVDLAHVVDEGEGDTSVA
                     EWRSAHERFWHSEEMRAALEDPEFTVDDTTLAVLERFRLVTDLHLAD"
     gene            14346..>15254
                     /locus_tag="B4U39_RS39775"
                     /pseudo=""
     CDS             14346..>15254
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981556.1"
                     /locus_tag="B4U39_RS39775"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS701 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGGERVDARSWAGELKALQERFAHRFSRLEPRESALACMQGLIAP
                     LERKNGWTLAEEAGHGGPDRIHRLLNRIDWNADEVLDDVRDYVIEHLGDPEAVLIVDDT
                     GFLKKGVRSAGVQRQYSGTAGRTENSQIGVFLAYASPHGRTLIDRRLYLPTSWTDDRER
                     CRAAGIDDTVAFETKVVTAKAMVRRAFADRVPFRWVTADAAYGFSKGWRTELERADVFH
                     VMATMRHDTVVTRWAMDRPVHDLFPGLARQKWKRRSCGDGAHGPRVYDWARVEVKPWHR
                     EDRRHWVIARRSIRRPEEISYY"
     gene            complement(15294..15890)
                     /locus_tag="B4U39_RS39780"
     CDS             complement(15294..15890)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357196.1"
                     /locus_tag="B4U39_RS39780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_079408457.1"
                     /transl_table=11
                     /translation="MTDYLAAAMAMLGPAQNRYADPAAWDRLHEDLGVRLPSDYRILID
                     AYAPVQLNGHLYLHHPATERWNLGTKIRNTAQAWSQVPWDDADPDEDPRVLFGLEELVF
                     GAENGLWPITSTDRGETVFLAPGPNAPCLLVEDGEGGWSQHSMSFAEWLYRYLIGEDMA
                     GPNSSAFYPGPVKLQRLPMSADERPEPWYDPDRDM"
     gene            complement(15974..16767)
                     /locus_tag="B4U39_RS39785"
     CDS             complement(join(15974..16434,16434..16767))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948683.1"
                     /locus_tag="B4U39_RS39785"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /protein_id="WP_162500733.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MVERLVPDGLWELFQRVVPAPPVRPQGGGRRRYGDRQVLAAIVFV
                     ATTGCTWRQLPPGFGPSGPTAHRRFTEWSRARVWGKLHRLVLDELGARGELDWSRCAID
                     SVNMRAMKRGDLTGPNPVDRGKKGSKIHLITERTGLPLSIGISAANTHDSQGLEALVRG
                     IPPIRSRRGPRRRRPAKLHGDKGYDYAHLRGWLRARHIVPRIARRGIESSQRLGRYRWT
                     VERTVAWLAGCRRLHRRYERKAEHFLAFAGIAAALICYRSLA"
     gene            <16816..17070
                     /locus_tag="B4U39_RS42165"
                     /pseudo=""
     CDS             <16816..17070
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719312.1"
                     /locus_tag="B4U39_RS42165"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS701 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="YIAYCPAETTLDELISVAGSRWAVEECFQTAKQECGLDDYQVRRY
                     DGWHRHMTLAMAAHACLTVLRAREADTGKAETDPPSSYP"
     gene            complement(17148..18062)
                     /locus_tag="B4U39_RS39800"
                     /pseudo=""
     CDS             complement(17148..18062)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046761.1"
                     /locus_tag="B4U39_RS39800"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRGDLTNAEWDRLESFLTCWWCPRGPVE"
     misc_feature    18216..18225
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.89"
                     /tool="antismash"
     misc_feature    18305..18320
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.84"
                     /tool="antismash"
     gene            19126..>19296
                     /locus_tag="B4U39_RS45060"
                     /pseudo=""
     CDS             19126..>19296
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013672272.1"
                     /locus_tag="B4U39_RS45060"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS701 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDDLFVTIGGHRFDRVELRRRMRDYVRPLLAPAARKNSWQLAEQA
                     GHTTPDGLQHLL"
     misc_feature    complement(19533..19549)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.23"
                     /tool="antismash"
     misc_feature    complement(20139..20157)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.18"
                     /tool="antismash"
     misc_feature    complement(20140..20156)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
ORIGIN
        1 caacgtgtcc ggcccagcaa ctccgggcgg acctgcgcgg gcaggtagcc aacgggcagc
       61 ggcgtcaccc gccacgctca gcacgccgcg gtcctcggca taggtctgtg cgcgggtgac
      121 gccttcgagg atggccgcct ggtcgaggtc gtcggggcag ttgtaggtcc aggggtcggt
      181 gaagaagctg aggttggcga catcgaccgt ggcggcagcc ggcaacaacc tgccgtacgg
      241 ccaggacctg gccaacaaga ccgtcgacat gagcagcccc aacgactcga cccccatctc
      301 gcggatgatc accagcgagt gcaagcacat tcccgctgaa ctgcccggtg tcgtcgcggt
      361 ctccgccatc gaggccgaca accgcaagtc cgcgtggtcc aactacgggg acaaccggat
      421 ccacgtcacc gcacccggcg ccggcgtcta ctccacggtc cccggcggcg gctacgagga
      481 acacatcggg acctccgtgg cagcccccca cgtctccggc gtcgccgcac tcctcctcag
      541 ccggaatccc gggatgagcc cgggcgacct ccgcagcgca ctcgccggcc aggccgacaa
      601 cctcccctgc cacgaccagt gcacaggaac caccgagaag aacagctact tcggagaagg
      661 ccgcgtcaac gcctaccgag ccgtcggcgg acaaaactaa ccccaaaaac acacccacaa
      721 acaaccactg cgcgtttttc agagtgggca ccgatccggt gatgtgaggg cggctgtgga
      781 acgagcccca gggctgttga gcaaggtctc tgcgctcaac tcttcagcct tggggctcgg
      841 ttggtatccc tggcgtgccg tactcgatgt cccgcatgcc ctcgtggagt gggtcgagac
      901 tcaccgtcac ccgcgagggt gatcgccggt gcaagctgcc gccggcgggc cggggccccg
      961 gccgcgctgg tgcacccgag ggacaacgag ccccccgccc agggcgcagc cgggttcggg
     1021 atcagcatgg gcaccgccca cgcctacgtc cacgcggtcg tgacgcttct gacccgactg
     1081 gacgccgggc ctgaccgcgg ccctgcgggc cgccagccag tacctcctgc tcgacgggac
     1141 cccccaccga gtgcgaccgg gtcggcgaca gcctcgccgg ctacctgggc aagcacgcac
     1201 atcgcgtgaa ccttcaggtc tcaccgcccg gacgaaccct cgttctggat ctcacccgca
     1261 cccgcgggcc ggatgcacca ccgcccaccg cccgtcgaca ccggatcatc ggccacctgt
     1321 atccgcctcg gcatccccgt cctcgcagac acgacagagc gtgtctcaaa gccgtgtaag
     1381 tccgcgatgt ggaagcctgg gccggggctc ggcctcgggc ctgtgggcca ggcggatcgg
     1441 acgagtcatg gaagacgaag acaaaggcga agcggccgcg cccgtgtccg acaacgagat
     1501 ggtcgacgag gtcgtcgagc gattgctcga caacgctgat gcctcaggag cggccctcct
     1561 cggtgaagga gggctcctga cggagatcac caaggccgtt ctcgagcggg ctctggaagc
     1621 cgagatgaat gaacatctcg gctagcgtgg cgatctggcc ggtcacggct ctgggaactc
     1681 gcgcaacggg gtgtcgccca agacggtcct gaccgatgcc ggagcaatca cgttggcggt
     1741 gcggtgggac cgccaacggc gagttcgaac cgcgtctggt ccccaagaac gcccgccggc
     1801 ttacaccggg atcaacgtcc ggatccactc gccctgagcc cccgcgggat gagtgtgagc
     1861 gacatccgct cccaccccgc ccagatctaa agggtcgaag tcagcccgaa cttgatcagc
     1921 aaagccaccg acgccgtgat cgacgagctc gtgacctggc agaaccgacc cctcgaccag
     1981 ggctggccga tcatctacat cgacgcgttg tgggtgaaga tctgcttcgg ttcggtgacc
     2041 tcgaagccgg tctatctggc cgtcggcgtc gactcggacg gccgcaaaga cctcctcggc
     2101 ctgtgggtcg gatggcgagg gcgccaccac atggatggcg gtcctgtccg agctgcgcaa
     2161 ccggggcgtc caggacgtct gcatcgtggt ctgcgacgga gtgaagggct tgcttgcccg
     2221 atggcgtgac cgcgcccaag gccaccgtcc agatctgcgt gatcctccca atcagggcct
     2281 cacttcgact gtcgtcatcg aaggaccact ccaagctggt gccggccatc aaggccatcg
     2341 acacggcccg acggagcgcc gagcaggccc tcggcctgtt cggcgcctgc tgacgtgtaa
     2401 acgacagcag gtcagggcgg gtgtgggcag ggctgggtgt ccggtggccg tcgaggggtt
     2461 cgcgggtgtc tggggttggc gatcaggctg tggtttccct ggggttgggg tggcggtgta
     2521 ggcgagctgg ttgggctggg ggaccgctcg gcgggtggcg cgttcggggt cgcgcctggt
     2581 gaagtgggtg ccgccgagtt cctggtaggc cccgcgttgt cggtgggcat gtgccggatc
     2641 gcggtgatga tcgagtgctc gacggtggcc agtgcccgca gggggccgcg gcgggcggtc
     2701 agccgcttgc agcgggcggc gaggtgggtg tccttggttc tgatcgcgcc gaacgcggcg
     2761 aggtcacggt tgcggcgcgg gtgccgtcgg ggctccaggg ggtggcagac gggttcccgt
     2821 agttgaagtc ctcgacgacg ctggcgggcc tgtccggtgt gtcctcgggc aggatgaaag
     2881 gtgaccttcg tgcagccctt gattgcttgc gttcgagcac ggaaatgact caagccacga
     2941 gaatgggcaa ccggccacgt ccttgcgccg gtgcgagtgt cgtgcagcga tacagcgccg
     3001 ttcgctgcgc gaaggtcact ctggtggacg cgagcatcgc ttggcctgca tcgaatgcca
     3061 gcgcagcgcc gcgcgcttgc cgccgcatgt ttccctcctc ggtccggagg tcgaccaaca
     3121 gatggcctgc gagcacggca tgcagctgtc ctggcgagca gggatgagaa agagagggtc
     3181 gagcgcaaaa gcgtacgggc gcgagtggtg ggtcgagtag cagccgacgg gaggagctga
     3241 acagtccaag gccaagacag caccgtgttc cggctcgtgc gaccatttgg acttcccgtg
     3301 atggacgcgt tcggccgtcg gccgcagttt gcctggtggg cgtgccgagg acgatgccaa
     3361 gcgcctttga tccgttaggg acacgtcggc agctcgatct gtggatcgcg ccccaacctg
     3421 tcgtgcgttt tcgctgcacg cctgctgcgt atggcgagct gtcgtgtcga cttcacggac
     3481 agggtaggcc gaaccttccc cggggtacgg tctgcttcat gactgatgac aagcacgccc
     3541 acccccggaa ttctaagggc gagcggatct gcaggcagtg cctcgacccc gacaagccgt
     3601 tgcgggaatc gctgggcagg aagccggtga tccactgctc aaagctctgc acgcggcggg
     3661 cgtacgagga gcgtagaagg caaaagaagg ccgccgcttc ggttccgatg aggtgaagcg
     3721 gacaccaggc ccgctcgggg agtgggcgtc aggtctcggt cggcacgcga tatcggcagc
     3781 ccggccagat actgagtgca gcaggatcgc agggaagctt cagagcaacg gggcgaggac
     3841 gagagcgatg atgcgggcag cgcgagcagg ccgatcagcc tgaccatccc gacggcggcg
     3901 ttcatcgcgt ccagcccact cacgcaaagc cgccgcatgg gatgcagtcg accggctccg
     3961 cctggcatga cgccagcact cccttgcgct gccctgtaac agcgagggca gctgccgccc
     4021 atgcccggtg acggtcctgc aggcggcgac ttcgtttccc agtcgacggt tggttgtgcg
     4081 tgaccgctag gctgcgcttg agccagcggg gtggagctgg actgactgcg ggcggcagac
     4141 cgggacagtc atagacaccc gggcaccacg cgcgggtatg gcggacgatg gagtgcgctg
     4201 aaccaggcag cgcgtcccgg cccggtacgt ggaccggcta cttgcttgcc gagacctccg
     4261 cgccgagcac ccgctcgttg caggacgcct gtggctttgt tggtgagttt caagaacgtc
     4321 tgatgctcag cggcaggaac gcccggttcc acgggagagt gatgtcgccg agtttcgaga
     4381 acacctcggt gcttgcttcg ggaccatggt tgtgctctgc acgacgaggg ggcccgggtg
     4441 ttgccgaagt ccaaggtcga tctgtacgcg gcgatccgtc gtgacgccaa gggcggcatg
     4501 tcgttgcggg cgctcatgcg gaagtacggc gtcggctacg agaccgtgca gaaggccctg
     4561 atctcggcaa tgccggaacc gcggaagaag atggagccgc gggagacacg gctggacccc
     4621 tacaagccgg tgatcgacgg catcctcacg gccgatctga ccgcacctcg caagcagcgg
     4681 cacaccgtca agcgaatcta cgaccggctg ctggacgagc atggcgccga catctcctac
     4741 cagatggtcc gtggctacgt cgctgcccgc cgccaggaga tccggctgga ggccggcaag
     4801 ggtgtggtcg acgcattcgt cccgcagacc cacaggccag gcgccgaggc cgaggtcgac
     4861 ttcggggacg tcacggtcaa gctggccggc gagctggtga cctgctacct gttcgcgttc
     4921 cggatgtcgt actcgggcaa agccgtccac cgcatcttcg cctcggcggg gcaggaggcg
     4981 ttcttcgagg gccacgtcca cgctctcaac gtgctgggtg gagtgcctac cgggaaggtc
     5041 cgctacgaca accttagagc cgccgtcgcc caggtgctgg gcctctcacg ccgccgggtg
     5101 gaggccgaac gctggactgc cttccgctcg cactacggac tggaagcctt ctactgccag
     5161 cccggcatcc gcggcgccca cgagaagggc ggagtcgaag gccagatcgg ctggttccgc
     5221 cgcaaccacc tcgtccccgt ccccgaagtc gacacgctcg ccgacctcaa cgccgtgatc
     5281 gaccggtggg accaagagga cgacaaccgc cgaatccgct cccggaccca cacgatcggc
     5341 gagtacttcg cgactgagca gccgctgctg gcaccgctac cggaagatcc cttcgagacc
     5401 ggccggctct ccacaccgcg ggtcgaccgc tacagccaga tctgcgtgcg gatgaaccgc
     5461 tactcggtcc cggtccggct gatcggacgg accgtccgcg tcatgctcca cgcctccgag
     5521 ctggtggtct acgacggccg cgaagaagtc gcccgccacg aacggctcat cgcccgcggc
     5581 gccacccgcc tcgaactcga ccactacctc gaggccctga tccggaaacc gggtgccctg
     5641 cccggtgcca ccaccctcga ccaggctcgt gctgccgggc ggttcacccc gatccacgac
     5701 gcctggtggc aagcctcggt gaaagcccac ggagaacgcg atggaacccg ggccctgatc
     5761 gaggttctcc tcctcagccg gcacctgcct cacgaacacc tcgtcacggg tctcgccgcc
     5821 gccctgcaga gcggggctct cacgtcagat gccgttgccc tggaagcacg caaggcagca
     5881 gacgccgaca ccgagcccga cgagacaccg ccgcccgccc ccggcagcca gaacggacac
     5941 gcgccgctgc ccgctgcagt ccgggcccgg ctgccgcccg acaaacgccc cctcccctcg
     6001 gtcgcccact acgaccagct cctgcggctc cgccgacccg atcacaacac ctgaggagaa
     6061 cgccatgacc cttccccgcc agcgaggact caccgaacaa gccgcgaaca ccgccgttga
     6121 ccaggcatgc cgcatgctgc ggctgcccac catccggtcc cagtttcccg agctggccga
     6181 gaaggccgaa cgcgagcaga tgtcctacct cggcttcctc gccgaactcc tcctcgccga
     6241 gtgcgacgac cgggcccgcc gccgctcaga gcgccgcatc aaggccgccg gcttcccccg
     6301 cgacaagtcg ctccgaaagt tcgacttcga cgccaacccc aacctcgacg cggccatgat
     6361 ccacaccctc gccaaatgcg aatggatcaa gaaggggctg ccgctctgcc tcatcgggga
     6421 ctccggaacc ggcaagtccc acctgctgat cgcgctaggg accgaggccg cgatggccgg
     6481 ctaccgggtc aagtacgtcc tggtgaccaa gctggtcaac gagctcgtcg aagccgccga
     6541 tgagaagcag ctgaccaaga ccatcgcccg atacggccgc gtggatctcc tctgcatcga
     6601 cgaactcggc tacatggaac tcgaccgccg cggcgccgaa ctcctcttcc aggtcctgac
     6661 cgaacgcgag gagaagaaca gcgtcgccat cgcctccaac gagtccttct ccggctggac
     6721 caagaccttc accgaccccc gcctctgcgc ggccatcgtc gaccgtctca ccttcggcgg
     6781 caacatcatc gaaaccggga ccgactccta ccggctcgcc accacccgag cacgcgctga
     6841 acagcagagc atcagctgac gacacattcc gatcccatcc tcggcgcggt ggacggtcgc
     6901 cagcacagaa gcccggtcct gttgtcaggc gggacagcag gcctcgcaga catggttgtc
     6961 gatcgcggcc accaacctct gagccgctgc ctgcacggcg acatccctgt cactagccag
     7021 cctgtccgcc aggctcctac catcgagcac tgctcggtga gcggcgtatt gaacgtcgag
     7081 ccgtggagga ttcgcctgtt cgaggatcgt ccgtagcagc tggatcacat cggcgcggct
     7141 tgcgacagag tcagtcaccg cgagatccca caggaacgga actgcctcgg cagtcgcgtc
     7201 gaagacagac agctctccga gccacagccc aagatcactc aacgctgaag cgctggtcac
     7261 cgcgtcgccc cacgccaccc gtgacaaccg gcccgggacc tcttccgctg atccatacgc
     7321 gtgcgtcagc tcgtgccacc gaacgcggct cacgcccttg agtatcgtcc ccaccgcgca
     7381 ccccagtcct agtccccgcc tgcgacgccg agcgccccca tttcacctca cggaacacat
     7441 cgaccgcgag cctgaccccc gatacactga cccgggcgtt cccagaactc gccaacattt
     7501 cacccaccgc cgagccccga acgctctcca aacccaccta catacgttcc gcgttctcac
     7561 ttacctagcc acgcctgctt ccgcgacacc gtgcagaccg actgctgatg gagttcaccg
     7621 ggatcgtccg gtcctgcgca ggttttcggt acagcaggga agtgcaccgg ccccgttggc
     7681 agcggccatg cgcgccacgg acccatcgcc tctaggccag ggcgcgcggc ctttctcgca
     7741 caccccgtgc ccagtctgtc ggacccgcca gcgagactgg catcagaagg gcgagggacg
     7801 gagaacacaa tgggcatcgt cggagacagt cgggagcgag ccgcgtcgca ggtagtcgat
     7861 acgcggacgg tctccaggag tgcgcgcgcg cggccggtac gctcacgcgt cccgcacggc
     7921 agcccgactt gcgccagcta cggatgcacc cggctcgggt gcagggcggc agcaagccgt
     7981 gaccgtgccc ggcgtgacag ggaacttatg gcggggcgtc ccgccagaat ttccgcattc
     8041 gaggccgcgt cgcgcgccgt cgtgctgcgc gatgccgggc tgtcagccgg cgacatcgcg
     8101 gaaatctcgg ggatttcggt cacactcgtc cgccgtctcc tgcgcttgcc cgccgaccag
     8161 cagccgccta tacaccgcac caccgccgaa gcggtcctgg gcgttccatt tgcgggcctg
     8221 tccggacggc gtcgccatcc cgggctggtc ccgtccgata cgagcgccac gctcctgcag
     8281 gaactttcgg tgaggggctg gcccaccagc ttcctcgcga accgccttgg cacgagtacc
     8341 cagaccctca ccgcgatccg cgcccgcaag cgaccgcgta tcagtctgac cctcgaccag
     8401 acgattcaga attgccaccg ggagctgacc gcaggcaccc ccgctgagta cggcatagcc
     8461 gcacaccgca gccgcagggc caacgcggcg gcccgccagc gggcccagaa cctcctgccc
     8521 cctcatcaag ccaccttcaa ccgcccctcc cccctcacta ggccaaagcc agcgatcgga
     8581 cagcgatcaa tgcagtgagc gcggcgccga tcgatacccc gtgctgaacc agagccccgg
     8641 gtgccgggac ccctctggcc ggcaaggaac ttgctccacg ccgacgcagt tgttcgatgc
     8701 gctgataaga gcagcaccgg cacgtaggag gaggggggca aaaggaagtc aacctggccc
     8761 ttcgcgtggt gagggtgagg aaatcacaga acaagaatcc ttcagaagcc gggcaagccg
     8821 tcacggataa agcgatcccg cgcccggctc cgccttgcca gcgcgcccgc gatccgttgt
     8881 gtccccttgc tccgggcagg taggcttccg ctgagcccac ccgtccgagg tggctcgtcg
     8941 atgcgtgcgc cgactctgct cgtggcctga cctggactgg cggcgatcct ggtgaggtca
     9001 ccaaccgggc tgcgacgacc ttcccgttgc tgggcagacg tccttgcatt gaggcccgat
     9061 atggtcgcac cgaagggcag cctcacaatt gcgtgcaccc acggtcgcga gttatcgcga
     9121 tagtaggcca ggccgtatcc gcctcccggc gatcatgaat attttcgcag gccaaaggct
     9181 atgagcagcc agtaatgcac gccgacacgc ctaatcgccg caattagggt tctggatcct
     9241 tgacgggccc gggacgacgt tgtccagccg ccagtcgtgt gtggtccgga cgtatcgtgg
     9301 tgacctctgc gacaccgccg accgtgcgag ccctgtggaa gaccggcgac gccgtggtgc
     9361 tggccggtct tctgatctcg cgaaccctcg aatccgagtg ctcgatggat gagatgccgg
     9421 acggttgacg cgtttctcct cacgaacttc gagctctgga caaggtttgc ggtccgcggg
     9481 tgccgcgcca ggttgatggc gatgtcttcc tgtcgtggtg catctgatct ttcagtgcac
     9541 ggctgggtag gcggtggccc agccgtgcac tgaaaacctc tctccatgga cccggacgcc
     9601 agcctgcatg cgatacccct gccagcacca cgtcactatg tccacgcagc cgatataccg
     9661 aaacgaagga attccacggc aatcgtgcac actgcgcaag ggtaaatgct gagctagggc
     9721 gcaacggccc tggcgcgttt acctgcgact cgcagaccag acatttacca tcaaatagcc
     9781 atccatgtcg cgaaccgaga tgctcgggta aatcgtactg acacaagaag ccgcaaatga
     9841 ggtgagggtg acatgttcga atggataaga gtattccctg ctggaactgc acatgtgatc
     9901 gaaaaatccc cagaactctt taaataggca ttccggatca gtcaaccctt gatcaatccg
     9961 gatagttcga gttcatcaaa aggctagaat gtaggacatc atgtttatct cggaaaattc
    10021 aacatgctat catcctcttg agcccgccat tcatcccatg gcagcagaaa tcgacgaacg
    10081 tgctgtttcc tggatgcact cattcgggtt gggtgcaaat aatgaggcac gtgaacggat
    10141 ggtgcactac agggtcggcc aactagccag ccgtatagtg ccagacggtc accatgaagg
    10201 cttgcaaata tttgcggatt tcttaacgtg gatattcgcg ctcgatgatg aatattgtga
    10261 cgagggcatg ctcggcagca agccgggtga attggcggat gccgtatctc gcatgctgtg
    10321 cgccttcgaa tctcccgaat ctctgatcga agatcctgcc gatcgctata gtcacgcgct
    10381 ccgggatctg cggctgcgtc tcgaaacctg tgcaacatca tcgcagattg ggtacctctc
    10441 aggaaccttg ggggggtatc tattgtctga ggttcgcaaa gctggctacg tgtccgcggg
    10501 gcggcatccg cgttccctcg atagctatgt acccatgctc atgcaaaatg gcggtactct
    10561 ggctatgatc gccttcccgc ctatcgtgca gggatatgag gttccgctgt cgctactgca
    10621 aagccatccc gccagagcgg tcaccgagat gtgcgcgact atcgctaact gtgattccga
    10681 tatcctctcc tactctaaag ggtggattcg gagtggtcat ggcttcaata ccatcgacgt
    10741 aatctgccgc gagtatcact gcagtgagca ggcggcattt atcgcggtca agggaatgcg
    10801 cgatcagatt atggagttat ttcttcgaat gtttcagcat ttgtcgtcgc atggagtgcc
    10861 aaatctagat cgctacatgg cgggcttgca ccgctacatg cgcggtgtga ttgactggca
    10921 ttccgaaacg gatcgatatg tgcattcggg tagagtcaag gaggattgtg aaatttctga
    10981 aaaatcggag tggggagacc ctgtcagcgt cttgcaatgt gatccacttt tgactcaagc
    11041 gacagcgtgg tggtggcgct acgacccgta ccgacgtcct gaagccgata tttaattgct
    11101 gcaaattgtt gcagatgctc accccgacga acgaggcaca gtcctggttg aattgaagcc
    11161 acccgcgggg cgctgtctgc gtacagactt gcttgctctg acaagatttt cgtaggcgga
    11221 gattctctct ttaatatttc ggcggtctac aaagagcaac ctgagactgt gctctgtttt
    11281 cttgggtatt ctgttatcgc agtcgtctga cgtgctcgtg gtttcgttgt ggtggcggcc
    11341 cgagcggcat gtacaggatg cagctggctc agcgggtggt gacacagccg ctgagtaaca
    11401 caacgtggtg cgcgattgag ggtagggcgg gctggcctgg ggtcatcgga tgggtgatcc
    11461 cctctcggcg gcacagccgg agagaccggg ccggcgacgg ccgagtgatc tcgtcgtggt
    11521 actcgcggcg tccgatccag cgttgtaggg gccgccgctg cttgtgcgcg gcgttgccgt
    11581 gcgcgacgca ggtctcctcc gaaggtgtcg agccctgtcc cagacggcca gtttctagta
    11641 gagctttgtt aggtggtgtt gtagggctgc aaggtgggtc gtcggcaggt ggggcaggtg
    11701 ccgatccagg tggcgatgag gtgttagagg aggtccaggg cctggtaggg ggtcagaccc
    11761 tgacaggtgg ggtcctcccc gctgtccgga ggaagaggtg ggccgcgatg atcagagtgc
    11821 cggtgtcggg cgttccgacc ccggccgcat gcatgatcag acagcgtttg aagaccgacg
    11881 gcatctgagg tccgttcgag tagttcccgg ggtcagggtc agggtcaggg ccagggcgga
    11941 cgccagctat ctgagcctgg ccaaagattt tcccaaccag gccgaggagc ctccgaagaa
    12001 accgaacaag aacgtcactc ttttagaccg tgtcctatgt ggtgaggcgg acgagtcgct
    12061 tgtagcagca gatggcggcg gcgagtccga gaaaggccag gtagttgcgg gggtggcgtt
    12121 tgtagcggtg gttgagtcgg cggtagccgg tgagccggga catggttcgc tcgatcaccc
    12181 accggcggcg gccaagccgc tcggaggact cgattccctt gcgtgcgata cgggactccg
    12241 atccgtttcc cgcgtaacca ttttcgcagg tggggaacgt cgtaggcctt gtcggcgtgc
    12301 aggcgtcggg gtgtgaagtg gcggccgcgg tgggggtcgt gtctcgttcg gtgacccacg
    12361 atcatgggct tcagcgcgag gctgtcgtgg gtgttggccg cggtgacacc gacgatgacg
    12421 ggcagcgcgt tcgcgtccga caggacgtgc atctcggaac ccggctcgcc ccggtccacg
    12481 ggactcggac ctgtgaggtc gccccccttt tttcgccctc acgtgggcgg agtccaggac
    12541 cgcccgggag agatcgagga ggccggcgtc gtcgaggcgg tgcaggatct cctcgtgcag
    12601 ccgaccccag actccggccc tcgaccagat caggaacctg cggtgagccg tcgacttcga
    12661 tatcccgaag cacggcggca gcgcccgcca ggcgcgcacc cgctgaccag gacataaatg
    12721 atcgcggcga acagcgtctc atcaggcgtg tcctgcgtcc cgccaccctg cgaccgcacc
    12781 ttcgacggcg gaatcagcgg ccccgcgatc tcccacaacc cgtccggaac aacccaactc
    12841 cacctacccc gccccatacc gacaccaacg acgcctcacc acataggaca cggtcttggt
    12901 ggatgttctg tgcgttgaag ttcggtttga cggcatctcg catcagtccg agaagtagcg
    12961 ttgggtcatg catacccgac gggacgcgga gccctcggcc tgcgtgatcg acgcccagag
    13021 cgtcaagacc tccaccagcg tccctgccgc aagccagggc atcgacgccg gcaagaaaat
    13081 cgcgggccgc aaacgaagca tcatcaccga caccctcgga ctcctcctca cggtgctggt
    13141 caccgcagcc aacgtccagg actccgtcgc cggcactcga ctcatcgacc aggtcgccgc
    13201 cgaacacccc accgttcgga aggtgtgggt cgacggcggc taccgccagc acctcgtcga
    13261 acacgccgcc accctcggca tcgacatgga gatctccgct cgcaagcccg ggaccagggg
    13321 attcacccca attccgaaac ggtgggcggt cgagcggacc tacggttggc tcatgctcca
    13381 ccgccgcctg gcccgagact acgaaaccct ccccggacgc tccgaggccc tggtcaacct
    13441 cgccatgacc gacctcatgg cccgccgcat caccggcgag aacaccatct cctggcgcga
    13501 cccgacagaa cagaccaaac aaccgatcct gggatgaaac agcgggataa aacgacctct
    13561 tagaagggct ctgttagctg gtcttgtcac gttgggtcac tggtagttcg caggttggta
    13621 cgagtactgg gggagcttgc tgcggttcgg gtccggttgg aagaggttct ctccgaggtg
    13681 ttcgcgcccc ttggtagcgg cgtaggcgaa cacgtttgca aacgtgagag gccgcacgtc
    13741 gggctggccg ggaatggtga agcccccggg cagtccccgc cacgtcaagg cccgctcctg
    13801 ctggccctcg cggcactggc agttatcgtg actcgcatga cgactgacgc caccccacct
    13861 gtgaacctcg catcgatgcc cagggccgag ttcgccttcc ccggcccgct ccgcgaccag
    13921 ctcgtcgcag cgatcctcaa cggttccaag acctccacca caggactcct tgtcgactac
    13981 gagcttgagg gggagcccct cccgaaagtc gggagccgct cggtggtcat cgactccgat
    14041 gaccgccccg tcgcggtcat cgagatcacg ggcgtgcggg tcgtcccgct ggcgcaggtg
    14101 gatctcgctc acgtagtgga cgagggggag ggggacacca gcgtggccga gtggcggtcg
    14161 gcccacgagc ggttctggca cagcgaggag atgcgcgctg cgttggagga ccccgaattc
    14221 accgtggacg acacgacgct ggcggttctg gaacgcttcc gcctcgtcac cgaccttcac
    14281 cttgccgact agtactgcaa cggtcttttc cgtgactgtt gggcaggtcg gtcgttggtg
    14341 tggttatggg tggggaacgt gttgatgctc ggtcgtgggc tggtgaactg aaggccttgc
    14401 aggagcggtt cgcgcaccgc ttctccaggt tggagccgag ggagtcggct cttgcctgta
    14461 tgcaggggct gatagctccg ctggagcgga agaacgggtg gacgctcgcg gaggaggccg
    14521 ggcacggcgg cccggaccgg atccaccggt tgctgaaccg gatcgactgg aacgcggacg
    14581 aggtcctgga cgacgtgcgg gattacgtca tcgagcacct cggcgatccg gaggcggtgc
    14641 tgatcgtgga cgacaccggg ttcctgaaga agggtgtccg ctcggccggc gtccagcgcc
    14701 agtactccgg aactgccggg cggacggaga actcccagat cggagtgttc ctcgcctatg
    14761 cctctcctca cggccgcacg ttgatcgacc gccgactgta tctgcccacg tcatggacgg
    14821 atgaccggga acggtgccgg gccgccggta tcgacgacac agtcgccttc gagacgaaag
    14881 tcgtcaccgc gaaggccatg gtccgcaggg ccttcgcgga cagggttccg ttccggtggg
    14941 tgaccgcgga cgccgcttac ggcttctcca aaggctggcg gaccgagctg gaacgggccg
    15001 atgtcttcca cgtcatggcc accatgcggc atgacaccgt cgtcacccgc tgggccatgg
    15061 accgccccgt ccacgacctg tttcccggcc ttgcgaggca gaagtggaag cgccgttcct
    15121 gcggtgacgg cgcccacggc ccgagggtct acgactgggc gagggtcgag gtgaagccct
    15181 ggcaccgaga ggaccgccgg cactgggtga tcgcccgccg aagcatccgc cggcccgagg
    15241 agatctccta ctacgaggtc atctcgtttg gggctggtgg tgaggttggt tcctcacatg
    15301 tcgcgatctg ggtcgtacca aggttcgggg cgttcgtcgg cggacatcgg gaggcgctgc
    15361 agcttcaccg ggcctgggta gaaggctgag ctgttggggc cagccatgtc ctcgccgatc
    15421 aggtagcggt acagccattc ggcgaagctc atgctgtgct gcgaccatcc gccttccccg
    15481 tcctcgacga ggaggcaggg agcgttcggc cccggggcga gaaagacggt ctcgccccgg
    15541 tcagtgctgg tgatcggcca aagtccgttc tcggctccga acacgagctc ctccaggccg
    15601 aacaggacac gcgggtcctc gtccgggtcg gcatcgtccc acggcacctg tgaccaagcc
    15661 tgggcggtgt tgcgtatctt ggtacccagg ttccaccgct cggttgccgg gtggtggagg
    15721 tacaggtggc cgttgagctg gaccggagcg taggcgtcga tgaggatccg gtagtcggac
    15781 ggcaagcgca ccccgaggtc ttcgtggagt cggtcccagg cggccgggtc ggcgtagcgg
    15841 ttctgggccg gtcccagcat cgccatggcg gcggccaggt agtcggtcat ggggttcctc
    15901 gttggtgtgg gtgcctggcc cgatgctcag cagtgggccg gcgccggtcg gaccgtcgga
    15961 atgacagcac ggatcatgcc agactgcggt agcagatcag ggcggcggcg atcccggcga
    16021 aggcgaggaa gtgttctgcc ttgcgttcgt agcgccggtg caggcggcgg cacccggcca
    16081 gccacgccac tgtccgctcc acggtccaac ggtagcggcc cagccgctgc gaggactcga
    16141 tgcctctacg ggcgatgcgc gggacgatat gccgggcacg gagccatccg cgaaggtgcg
    16201 cgtagtcgta gcccttgtca ccgtggagct tggcgggccg tcgccgacgg ggcccgcgcc
    16261 gggagcggat cggcgggata ccccgcacca aggcttcaag gccctggctg tcatgggtat
    16321 tcgcggcgga gatgccgatc gagaggggca gaccggtccg ctcggtgatc aagtggatct
    16381 ttgaaccctt cttgccgcga tctacgggat tcggacccgt cagatccccc ctttcatcgc
    16441 ccgcatgttc accgagtcga tcgcacaccg agaccagtcc agctcgcccc gggcgccgag
    16501 ttcgtccagc accaggcggt ggagcttgcc ccagacgcgg gcccggctcc actcggtgaa
    16561 gcggcggtgc gcggtcggcc cggacgggcc gaaccccggt ggcagttggc gccatgtgca
    16621 gcccgtcgtg gccacgaaca cgatggccgc caacacctgc cggtccccat acctgcgccg
    16681 gcccccaccc tgaggccgta ccggaggagc cggtaccacc cgctgaaaca gctcccacaa
    16741 cccgtccggg accagacgct ccaccatcgc catcacggca gtcagcctag tgatcaagcc
    16801 agttgagacg acctctacat cgcctactgc ccggccgaga ccacactcga cgagctcatc
    16861 tctgtcgccg ggagcagatg ggcggtcgag gaatgcttcc agaccgccaa gcaggagtgc
    16921 ggtctggacg attaccaggt ccgccgctac gacggctggc accgccacat gaccctggcc
    16981 atggccgccc acgcctgcct caccgtcctg cgagcccgcg aagcggacac agggaaagca
    17041 gaaacggatc ctcccagctc atacccctga ccctccccga actccgacgc ctgatccacc
    17101 gcctcgccca ccgccgcccg gcacccaccg accacgtcct gcactggtca cactggcgac
    17161 ggcgacgaca gttccaagcc cgcatcagcc actacaaacg acgcggttgc gacggcgcgg
    17221 aagcccttga ggcggttgat ggctcgttcg acggtgttgc gtttcttgta gcgctcgcgg
    17281 tcatagccgg tggggcggcc gcctcgggag cctcggttct tgcggtgtct ttgctggtcg
    17341 aggcgttcgg ggatggtgtg ccgaattccg cgtcgtcgca ggtaacggcg gttcttccgg
    17401 gacgtgtagg ccttgtccgc caggacatgg tcggggcgag tccggggcct tccgacaccg
    17461 ggtcggggcg cggagacctg ctccagtact cgctcgagct ggggtccgtc gccgtggtgt
    17521 ccgggtgtca ggacgagagc gaggggccgg caccgcccgt cggcggcgag gtgaatcttg
    17581 gtggtgaatc cgccgcggga gcgtcccagg tacctgccga tctgaccacc tccaggagcc
    17641 ggaggaccag tttccgcagc accggatcga cctggttcgt cccccgaacc ttcccccttt
    17701 gaggatctgc ggccagcggt gccttcctcg cgccggcggc atgctggtgg gcccgcaccg
    17761 cggtcgagtc cacggacacg tcccagtcga tctggcccgc ggcgtcctcg gccgcctgga
    17821 tccgggacaa gagcatcgtc catgttccgt ccgctgacca gcggcgatga cgtttgtaga
    17881 cggtctccca cggcccgaac cgctccggta gatcccgcca ctgcacaccc gtccggaccc
    17941 ggtagagcac cccgttgatc acccggcggt gatcactcca ccggcccccg cgggcaccac
    18001 cagcaggtaa gaaacgactc cagccgatcc cactccgcat tcgtcagatc tccacgaccc
    18061 atacagacag cctgacccca acaccccgcc cacttcatga gatccaagaa acagtgccta
    18121 atcattcgtc cgctcaccac gccgtaagga acctcgccga cctcatgctc gcgggcacac
    18181 gcctcaagcc ttgtagcgcg atacacgact tgcccgaagg cgaccttgcc gagcaagtgc
    18241 cgggggctga ctgcgcgctg gcgacctcgt gcacggttgc tccgagggcg tgtgcagcag
    18301 tggatggact ggttggtcat gctctggcgg gtagggcggt ggaggggcga gtcgcctgct
    18361 ggtcggtgag gaggtcggtg actgctcgga tggtgtcgac agggtttcgc gtcggctgtg
    18421 gtggcgtgag agggctcgcc ggtcttgagg tgggcgatgc cgtgttcgac cgggatccgg
    18481 gctgatgagt gggcgaaccg ggccgcttcg tggtgtgcca tgaggcattg gaggtgctcg
    18541 aggtgtttgc ctcgtctttg cgtggcagtg tgatgacctg gccgcaggtc tgggcgccga
    18601 ggccctgata gccggcatcg gcgagtatct gcaggtcgat gctggcggtg aggagatcga
    18661 ccaggctggc gtcacgggct tggtggagcg gtcaaccccg agccagcggg ccggcacctt
    18721 gtatgtggca ccgtggcgga ggtggatgag cgtaggcggg gagccggtcg atggagccag
    18781 ccggtgcttc acaccggcgc cgacggcccg cttccgcggc ctggcctcca gtcccgcctg
    18841 atggcgttcc tgacataacg gcccgacctc ggcaacgagt cggcgatcac atcggcagac
    18901 ggccccatga tcctccggtc gctgacgatt gctgcacgag accgttccca ccacacgagc
    18961 atgatcaggg accacgatcc agcgtcgtac ccccaaccat gcgcgagctc gttagtactc
    19021 cagcaggatt ttgatgtctg acctgcgggt ttcgctaagt agtggcagcg gcggggcagc
    19081 ttccccaggt gatcagcgcg tgtcggcgag caatgggacg gggacctgga cgacctcttc
    19141 gtgaccatcg gcggccatcg gtttgatcga gtggagctac gtcgtcgcat gcgcgattac
    19201 gtacgcccac tgctcgcccc agcggcccgg aaaaacagct ggcagctggc tgagcaggca
    19261 ggccacacaa cccccgatgg cctgcagcac ctactcgccg gagcaaagtg gaaccccgac
    19321 acctggacca tatgcgggat gacggagcta tcctgcaatg ggggcgcctg acgatcttcc
    19381 ggctcgaccg gtccgatcta tcaggacgcc ccctttcctg gttcctcagg cttgatccgc
    19441 gactcggaat gcaaatgaca atggcgtttc cgatgtcata ctgactgacc tgatctcctt
    19501 gtggggaacg tcagaactcg ccgcttgaga gaatgtaata aaagtcaact attggctaga
    19561 attgcagcat ccaccggtcc agacgcccgt caaatgtctc agaatcggcc ttcgtgtccg
    19621 ttatcttgag cttccactgg ccgttaggag cctcacttga tgcgtcaacg ttgaactcct
    19681 ggaaaagatc atttccggta tccgagttcg ggtggtagaa gcggtaggaa gttccatcag
    19741 gagcgatcag gtcgagtgcg aggtcacccc tggtgtggtg cacaatgttc accttgactc
    19801 gcaggtactg ccgtgctttc gcgtctccct gatcgctgac aaccgtggcg ctcgaagtta
    19861 ccgaaccatt gtccaccaga ttggccgggg tggagttcac atagtgccct cccacatgca
    19921 ggagatagga aggcgagttc ggcattccaa caagagtgct ttcgctcgct tcttgctgta
    19981 ggcgggcttt aactgcagct gccgaactgt accctcgagc ttggagaata gcagcggctc
    20041 ccgccacggc tggcgttgaa gctgatgtcc caccatagtt catgctgccg tcaacggaat
    20101 cgttgctggc agcaggcacg ttgacgccag gtgcccacat tgcgacgcat gcgccataat
    20161 ttgaggaacc tccgttttcg aacgtggctc gagtgtccgc ttcgttggtt gcgccaacaa
    20221 caattacgtc cgggcgtcta tatactggag atgaatcttc gtcgcatacg ttattcccga
    20281 aattgtgcgc agcgataacc acagaggttc cagaatttgt aagctgggta atcgcattcg
    20341 agaaacctgg caggtcggta accagggaag acatgctcac taccgcttta tggggaatcc
    20401 tgttggggtc atttacgatc caatccagcc ctctgatcat ctgatcgcca gtggtatttc
    20461 catcgcaatt gaaccactta acattcacga tgtctgcgcc gcgcgcggta ccgtatccgt
    20521 gatttacatc gccgctatct ttcgtgtagg cagctccggc tgccacgctc gcggatgcag
    20581 taccgtggta cctgcaatcc tcaccgggtg cgtagcctcg gctcggatcg ctcgttacgt
    20641 cggtgccgaa cttgaggcga ttcccgaaag ttcggtgagg attgattcct gagtcggtca
    20701 catagatacg cgtaccggcg ccgcttccgt cgcctgtagg attatttgcg ttgaattttc
    20761 cgtccagcgg gcgcttgcgc tgatcgatcc ggtccatgtt ccaggatgct tcagtttcaa
    20821 cagcctgagg cttagctccc tcaatagcgg gtgcatattc ctctgttatt tctacgtcct
    20881 gttcgacgta gtcgacgacg gtgttttccg ctagccgacg cgcatccgcc tcgctcatgc
    20941 tgacggaaaa cccgttcatc gcactttcga aaacaaatct cacctttccg ttatattgcc
    21001 tggcgatatc atctgcgata ttttttcgat cttcgaggct ctcaggctgc gttttcaggg
    21061 tgaccaaata ttggttttct actccatttt ctgtc
//
