LOCUS       NZ_CP020040            22814 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence.
ACCESSION   NZ_CP020040
VERSION     NZ_CP020040.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. 3211
  ORGANISM  Streptomyces sp. 3211
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 518852)
  AUTHORS   Heinsch,S.C., Hsu,S., Hansen,L., Kinkel,L. and Smanski,M.J.
  TITLE     Complete genomes of three Streptomyces isolated from disease
            suppressive soils
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 518852)
  AUTHORS   Heinsch,S.C., Hsu,S., Hansen,L., Kinkel,L. and Smanski,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAR-2017) Biotechnology Institute, University of
            Minnesota, 1479 Gortner Ave, Saint Paul, MN 55108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-JAN-2017
            Assembly Method                   :: PacBio v. Jan-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:18:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,254
            CDSs (total)                      :: 8,154
            Genes (coding)                    :: 7,815
            CDSs (with protein)               :: 7,815
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 340
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 340
            Pseudo Genes (frameshifted)       :: 206 of 340
            Pseudo Genes (incomplete)         :: 257 of 340
            Pseudo Genes (internal stop)      :: 68 of 340
            Pseudo Genes (multiple problems)  :: 153 of 340
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:04:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 275058
            Orig. end                         :: 297872
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020040.1.
            Bacteria and source DNA available from Michael Smanski.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22814
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22814
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22814
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12814](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12814
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     CDS             complement(340..447)
                     /gene="allorf_275398_275505"
                     /locus_tag="allorf_275398_275505"
                     /protein_id="allorf_275398_275505"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSDGLLEMRSAGSPRRVPCITASADNVLPFTCCEK"
     CDS_motif       complement(409..447)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSDGLLEMRSAGS"
                     /locus_tag="allorf_275398_275505_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(340..408)
                     /prepeptide="core"
                     /locus_tag="allorf_275398_275505_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="2366.8"
                     /monoisotopic_mass="2365.2"
                     /core_sequence="PRRVPCITASADNVLPFTCCEK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDGLLEMRSAGS"
                     /leader_location="[408:447](-)"
     gene            complement(440..1744)
                     /locus_tag="B4U39_RS38775"
     CDS             complement(440..1744)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="B4U39_RS38775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_079408345.1"
                     /transl_table=11
                     /translation="MKFPVIPALPGVAWGVLAVVTISSVGTGLTLPFELFYLHQVRGLS
                     LSQAGLVMAVSTLIAFGGNSLGGVLCDRFGFRRTLTLGLVVEGFGVLALANATEFWQAI
                     AAVVVTGAGGGIAWPAQDALIATTVSEEMRSTAFAMRHAALNVGLGVGGLLAVMVTKSE
                     DPGSFVALFLLDTLTFFLAAGALWLIRLVAPATTPTSEAPGAGTGGGYRAVLRDRTFLR
                     LWLIIFLLVTAGYAQLNSAVPAYLTGQGFQPGLLGVFAAVNAVTVVVAQVVVLRYIGGR
                     RRTSLIAVLCVLWSAAWAALILITEVDGAWALVLVVVAASVFAVGETLLAPTAPVLVNA
                     IAPDDMRGRYNGLTASAFTLGAFVGTLTAGIVLDGGYGRMHFMACIAVLALIALLALRL
                     STHLPRAANLGDPEDTAPGDLGSAKEHARLGSNDV"
     gene            2004..2564
                     /locus_tag="B4U39_RS38780"
     CDS             2004..2564
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS38780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_079408346.1"
                     /transl_table=11
                     /translation="MEVQAALRRYAFLDYNLTVVLDVQAALRRYAFLDYNLTVVLDVQA
                     ALRRYAFLDYNLTVVLDVQAALRRYAFLDHNLTVVLDVQAALRRYAFLDHNLTVIHVQA
                     ALRRYAFLNHNLTVIHVQAAKAGRVVRVGHGVSPFCRCSTYIVTASDSSLWKSLRAPLR
                     NRFAITSISLQRLDVTVRTVLSE"
     gene            complement(2802..3314)
                     /locus_tag="B4U39_RS38785"
     CDS             complement(2802..3314)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="B4U39_RS38785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_079408347.1"
                     /transl_table=11
                     /translation="MTTTVEDRLEEQLDDLLALWPDEPAPLPAPARTAAPVTGVTDGIT
                     ECTLAHDTTAPTIARHIARTLLAAHDLPDPVIDSALLVTSELVTNAVEHALAPLTLHIH
                     PEHTGGRVWIGVTDGGPATHDGAWTTSCTEDEHGRGRAVINALADTHGTHTHTNGHTTH
                     WARIPTT"
     CDS             complement(3393..3560)
                     /gene="allorf_278451_278618"
                     /locus_tag="allorf_278451_278618"
                     /protein_id="allorf_278451_278618"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTPRRVFTARSRAKPGRSQSPAWQLIRSAGMLSVVVCSRLIRLGG
                     IWFVIGVKGG"
     CDS_motif       complement(3468..3560)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTPRRVFTARSRAKPGRSQSPAWQLIRSAGM"
                     /locus_tag="allorf_278451_278618_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3393..3467)
                     /prepeptide="core"
                     /locus_tag="allorf_278451_278618_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.20"
                     /molecular_weight="2493.1"
                     /monoisotopic_mass="2491.5"
                     /core_sequence="LSVVVCSRLIRLGGIWFVIGVKGG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTPRRVFTARSRAKPGRSQSPAWQLIRSAGM"
                     /leader_location="[3467:3560](-)"
                     /alternative_weights="2511.1"
     misc_feature    3406..3421
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     gene            complement(<3761..4106)
                     /locus_tag="B4U39_RS38790"
                     /pseudo=""
     CDS             complement(<3761..4106)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_053126455.1"
                     /locus_tag="B4U39_RS38790"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS110 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIDTSAIGAFLGLGVGRGEHHTTAVTPAGKKAFDKRLAQQRAQAP
                     RGPRETAGQARGPCSWSSWTSRPPSALCR"
     CDS_motif       complement(4080..4106)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIDTSAIGA"
                     /locus_tag="B4U39_RS38790_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3762..4079)
                     /prepeptide="core"
                     /locus_tag="B4U39_RS38790_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="6775.6"
                     /monoisotopic_mass="6771.6"
                     /core_sequence="FLGLGVGRGEHHTTAVTPAGKKAFDKRLAQQRAQAPRGPRETA
                     GQARGPCSWSSWTSRPPSALCR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIDTSAIGA"
                     /leader_location="[4079:4106](-)"
                     /alternative_weights="6793.6"
                     /alternative_weights="6811.6"
                     /alternative_weights="6829.6"
                     /alternative_weights="6847.7"
                     /alternative_weights="6865.7"
                     /alternative_weights="6883.7"
                     /alternative_weights="6901.7"
                     /alternative_weights="6919.7"
     gene            complement(<4523..>4671)
                     /locus_tag="B4U39_RS44905"
                     /pseudo=""
     CDS             complement(<4523..4671)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611377.1"
                     /locus_tag="B4U39_RS44905"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFSAPDTYWRGDIAYLATREGRLCSATVIDIASAASSAGRPPITC
                     EPSL"
     CDS_motif       complement(4564..4671)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MFSAPDTYWRGDIAYLATREGRLCSATVIDIASAAS"
                     /locus_tag="B4U39_RS44905_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4525..4563)
                     /prepeptide="core"
                     /locus_tag="B4U39_RS44905_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="1273.4"
                     /monoisotopic_mass="1272.7"
                     /core_sequence="SAGRPPITCEPSL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFSAPDTYWRGDIAYLATREGRLCSATVIDIASAAS"
                     /leader_location="[4563:4671](-)"
                     /alternative_weights="1291.5"
                     /alternative_weights="1309.5"
     gene            complement(5129..5284)
                     /locus_tag="B4U39_RS43065"
     CDS             complement(5129..5284)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS43065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159395808.1"
                     /transl_table=11
                     /translation="MASMEKKRALPRRSFTPEFKAEIVELCRRGDRSAGQAARDFELTE
                     TAVRAG"
     gene            complement(5401..5631)
                     /locus_tag="B4U39_RS43070"
     CDS             complement(5401..5631)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS43070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159395809.1"
                     /transl_table=11
                     /translation="MTDTGVSVRLTPNGFLVTCSGTDVVGHGPTETDAWNDFLAASRAQ
                     WQPPVRAPGPLLPAKVKHKRTRTLRIRDLFG"
     misc_feature    5862..5876
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            6219..6641
                     /locus_tag="B4U39_RS38795"
     CDS             6219..6641
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS38795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_079408348.1"
                     /transl_table=11
                     /translation="MVAALDTLADVPPPADREAVHEEYLRRVIPQFTGHQVGEIITWST
                     AHGDLHYGNVTRAPHILDWKGWGRAPYGYDAATLYLYALLVPAAAARIRTELAPSWTGP
                     RRAGPLTVCAQILQAQDRTAFYAELDSPVREQFPHL"
     CDS             complement(7128..7367)
                     /gene="allorf_282186_282425"
                     /locus_tag="allorf_282186_282425"
                     /protein_id="allorf_282186_282425"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSARHNGPDAPQSPVRPAKTATALDSVPGSFDVRSAASAIRAATG
                     AALRRPVWPASTCPFCAVCERFARRATPPPLAVA"
     CDS_motif       complement(7278..7367)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSARHNGPDAPQSPVRPAKTATALDSVPGS"
                     /locus_tag="allorf_282186_282425_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(7128..7277)
                     /prepeptide="core"
                     /locus_tag="allorf_282186_282425_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.30"
                     /molecular_weight="5048.9"
                     /monoisotopic_mass="5045.7"
                     /core_sequence="FDVRSAASAIRAATGAALRRPVWPASTCPFCAVCERFARRATP
                     PPLAVA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSARHNGPDAPQSPVRPAKTATALDSVPGS"
                     /leader_location="[7277:7367](-)"
                     /alternative_weights="5066.9"
                     /alternative_weights="5084.9"
                     /alternative_weights="5102.9"
     gene            complement(<7387..8286)
                     /locus_tag="B4U39_RS38800"
                     /pseudo=""
     CDS             complement(<7387..8286)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008749716.1"
                     /locus_tag="B4U39_RS38800"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSAVVQLLPTAKTLIVRTAADVFLDSLGNPNTVRN"
     CDS             complement(8340..8468)
                     /gene="allorf_283398_283526"
                     /locus_tag="allorf_283398_283526"
                     /protein_id="allorf_283398_283526"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSDRALAVAPGGRLPSLWLRDGPEVVPQITPNICGSLIRHLW"
     CDS_motif       complement(8433..8468)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSDRALAVAPGG"
                     /locus_tag="allorf_283398_283526_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(8340..8432)
                     /prepeptide="core"
                     /locus_tag="allorf_283398_283526_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.50"
                     /molecular_weight="3413.0"
                     /monoisotopic_mass="3410.9"
                     /core_sequence="RLPSLWLRDGPEVVPQITPNICGSLIRHLW"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDRALAVAPGG"
                     /leader_location="[8432:8468](-)"
                     /alternative_weights="3431.0"
                     /alternative_weights="3449.0"
     misc_feature    8715..8729
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     CDS             complement(8791..8967)
                     /gene="allorf_283849_284025"
                     /locus_tag="allorf_283849_284025"
                     /protein_id="allorf_283849_284025"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAAHIKGAGLCMPGNMGGHICRCPVYDPLRPGIPCRISARMAQRW
                     CRQPRGRLRLLRT"
     CDS_motif       complement(8944..8967)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAAHIKGA"
                     /locus_tag="allorf_283849_284025_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(8791..8943)
                     /prepeptide="core"
                     /locus_tag="allorf_283849_284025_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.60"
                     /molecular_weight="5684.8"
                     /monoisotopic_mass="5680.9"
                     /core_sequence="GLCMPGNMGGHICRCPVYDPLRPGIPCRISARMAQRWCRQPRG
                     RLRLLRT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAAHIKGA"
                     /leader_location="[8943:8967](-)"
     misc_feature    8974..8986
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     CDS             9308..9538
                     /gene="allorf_284366_284596"
                     /locus_tag="allorf_284366_284596"
                     /protein_id="allorf_284366_284596"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRLIPRSAGTQLPASRHFEANHNFARDRPSFQLYEAISQCITIVL
                     RADITVARVLSRWQIQSRAPPLGCRRATLHG"
     CDS_motif       9308..9382
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRLIPRSAGTQLPASRHFEANHNFA"
                     /locus_tag="allorf_284366_284596_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9383..9538
                     /prepeptide="core"
                     /locus_tag="allorf_284366_284596_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="5694.6"
                     /monoisotopic_mass="5691.1"
                     /core_sequence="RDRPSFQLYEAISQCITIVLRADITVARVLSRWQIQSRAPPLG
                     CRRATLHG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRLIPRSAGTQLPASRHFEANHNFA"
                     /leader_location="[9307:9382](+)"
                     /alternative_weights="5712.6"
                     /alternative_weights="5730.6"
                     /alternative_weights="5748.6"
                     /alternative_weights="5766.7"
                     /alternative_weights="5784.7"
     CDS             9495..9608
                     /gene="allorf_284553_284666"
                     /locus_tag="allorf_284553_284666"
                     /protein_id="allorf_284553_284666"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRRRWVAGGQRCTDEHSPIAVWEAPANVNRTGDCLVP"
     CDS_motif       9495..9521
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRRRWVAGG"
                     /locus_tag="allorf_284553_284666_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9522..9608
                     /prepeptide="core"
                     /locus_tag="allorf_284553_284666_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.50"
                     /molecular_weight="3025.3"
                     /monoisotopic_mass="3023.4"
                     /core_sequence="QRCTDEHSPIAVWEAPANVNRTGDCLVP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRRRWVAGG"
                     /leader_location="[9494:9521](+)"
                     /alternative_weights="3043.3"
     CDS             9708..9908
                     /gene="allorf_284766_284966"
                     /locus_tag="allorf_284766_284966"
                     /protein_id="allorf_284766_284966"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPQLMTVDPEAVIDAWRRDEAMFGLESPAGARFVLGVPSVDAEFR
                     GDTWETCAPTCTEPESVPENS"
     CDS_motif       9708..9800
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPQLMTVDPEAVIDAWRRDEAMFGLESPAGA"
                     /locus_tag="allorf_284766_284966_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9801..9908
                     /prepeptide="core"
                     /locus_tag="allorf_284766_284966_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.50"
                     /molecular_weight="3701.0"
                     /monoisotopic_mass="3698.7"
                     /core_sequence="RFVLGVPSVDAEFRGDTWETCAPTCTEPESVPENS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPQLMTVDPEAVIDAWRRDEAMFGLESPAGA"
                     /leader_location="[9707:9800](+)"
                     /alternative_weights="3719.0"
                     /alternative_weights="3737.0"
                     /alternative_weights="3755.0"
                     /alternative_weights="3773.1"
                     /alternative_weights="3791.1"
     misc_feature    9956..9970
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.47"
                     /tool="antismash"
     gene            10001..12814
                     /locus_tag="B4U39_RS38810"
     CDS             10001..12814
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="B4U39_RS38810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_159395810.1"
                     /sec_met_domain="DUF4135 (E-value: 1.1e-72, bitscore:
                     240.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.7e-40, bitscore:
                     133.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAVAVLVDSFNVELREYLDNVSGLEQYEVEIFHSAACKDLSSIF
                     LARLTPLLLLELNAARLRGQLTGDTAEARWRSFLGRCSAGEFWPYAFEVYPALPGRLRR
                     VSRNALESCVEMAQRFVLDRDALRSIFGALTLTDVETGLGDGHRGGRKVARFIFGATSV
                     LYKPRPLDADAALAHLLDDLQPEAEDSWIRVPAVYTRSGYGWAEFVEHAYCTDSSEEAD
                     FYRAMGAWVAVMVLIRGTDLHFENVIACGAMPVVVDCETLFTPPPTPFNHGMSLASVEA
                     RKRMRQTGLTTGLLPWRSPQPAPGRAGVDLSALGALPEEQPAFAVPMVQGNGSDDARLV
                     VRDAKIVSGRNHPVLAPQPERYKAEIIDGFRDFADRIGALDRAGKLESALQRFARCEVR
                     LVTRATRVYYSISRALWHPSSLRDECAAVREVVDLLVQRREKDLHACCESGEVRAEIEE
                     LLYGDIPIYIYAPEEGIVAGAGRLPNPEYGNQLDSALSGWRNIDLPFQEAVINASFAGA
                     VRDAHRVAMTGQASSTGLIPASTEQNPQLKDSLRKAVERLAAEAIRGTDGSVTWIGRGF
                     EDSGSPWGPVSMNLYNGQAGIVFSLAAYEQAVRNGHVEAVSGLDEIVRAATDVLVAEQE
                     KSVTSGRAGSGGYTGAGGALWTWLALHNITQDNRMLKCAIRAAESFHGAPDEDVYDLLN
                     GVAGGIVPLIGLAELCKDDAYLDQATALAELVSQSALPQEIGVCWPSNLSRRGVGGFSH
                     GVTGIGWALKRLGMAARDERWGNLGDQAFLFEESLYQPGKGWRDLRYLNAASFQHAWCH
                     GSTGIGLAALDLFKQTGSEEYQERSVRAIAHCAGESRNSLGNSLCHGLLGNLEFIYRIH
                     EGKIANGSNFIDEMEISLGLEISRVLHESGPLIDPGLMTGMSGHIYSALSADRRISLPS
                     PLTLEVR"
     CDS             12868..13035
                     /gene="allorf_287926_288093"
                     /locus_tag="allorf_287926_288093"
                     /protein_id="allorf_287926_288093"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRIPDETRDQLAVKFAVLDERQRRLLIGEGLLAWCGLRHLHRRPE
                     RSLCPTVIHP"
     CDS_motif       12868..12915
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRIPDETRDQLAVKFA"
                     /locus_tag="allorf_287926_288093_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12916..13035
                     /prepeptide="core"
                     /locus_tag="allorf_287926_288093_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="4561.3"
                     /monoisotopic_mass="4558.5"
                     /core_sequence="VLDERQRRLLIGEGLLAWCGLRHLHRRPERSLCPTVIHP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRIPDETRDQLAVKFA"
                     /leader_location="[12867:12915](+)"
     gene            13306..15144
                     /locus_tag="B4U39_RS38815"
     CDS             13306..15144
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010352522.1"
                     /locus_tag="B4U39_RS38815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_237297276.1"
                     /transl_table=11
                     /translation="MRHEGASHRISFLQVVFRLPQMLGMIVRLAWAADRRALVTVVAAE
                     LVRGAALAFGLLTVNRVFVSLLASGPTPDKLHTALPPLMLMGAAAAIGVGAGSLSTAAA
                     GRLEPKVERTTTVQFLERAIRVELLAIEDPEFHRLLDSAEYGTRAARQMIGQTVAVANA
                     CLTLAAAGGVLAVLHPALLPLLALIAAPKGWGAVRTARRRYESTLAWVQHARASTVVAK
                     LLTDPLVAPEVRVHGAGSFLLRHFEGMSADAEAEQTRLARSQASTDLAAASLSGIASAV
                     AYLTLGLLLNSGIMDLAVAATAALAIRSGAANITTFVTQINGLYREALFLQDLQEVCIE
                     GDRRAIPEGGTAPRATPEVIRLHNVSFTYPGRGRPAVNNVSLTIRRGQVVALVGENGSG
                     KTTIAKLVAGLYEPDDGTLTWDGTDVRELDREQVFSKIGLLTQDFPRWPFTAQANIAIG
                     NPQLPVETHALTASAHYANIDQMIKNLPKKWDTLLARQFTGGVELSGGQWQRLGLARAH
                     YRSAPILICDEPTSALDPKAEIEAFEKIRALTDQGHTIVLITHRLASVRHADTIYMLSN
                     GQLIESGTHQQLLGQEGRFAELFHLQANQYQPPDHP"
     gene            15202..>15401
                     /locus_tag="B4U39_RS38820"
                     /pseudo=""
     CDS             15202..>15401
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114989.1"
                     /locus_tag="B4U39_RS38820"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MARRKPWEVDGESGRWSSGGFVIRGGSGIRTGWCSRAPCSFCTPG
                     SRGNISRRSWASDRA"
     gene            complement(15456..16397)
                     /locus_tag="B4U39_RS38825"
     CDS             complement(15456..16397)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093549.1"
                     /locus_tag="B4U39_RS38825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="recombinase family protein"
                     /protein_id="WP_237297277.1"
                     /transl_table=11
                     /translation="MSRCTGPDAVCFICGTSTDAGLLAARQDLVLAEAGIEDPVVFEED
                     PGASSRLHPLQRPKFGELLTYARPGDTVHISEMFRLVRGNQHILDVLDVLHRDRLALRI
                     HDGAFSAMDLTARHPRTGELLSTVKFMVQTLAAAGELQRDLQRELTYDGLRAAEAKGNK
                     GGRRPAVAATKTADVRTAYLEGCSIAALARDHGVSRGAIRTAIADLLPDHSASQEDAPA
                     PELPVTLDMPGKVADYLHTTELEPAERVALDQGMTVRRGQGYTLCVSALPAVHRQLLTH
                     CQPLDGAQGVPAVPAQRKARREYENRVSALTP"
     gene            complement(16400..19521)
                     /locus_tag="B4U39_RS38830"
                     /pseudo=""
     CDS             complement(16400..19521)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055826.1"
                     /locus_tag="B4U39_RS38830"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="Tn3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPVEFLSDEQAEA"
     CDS             19608..19793
                     /gene="allorf_294666_294851"
                     /locus_tag="allorf_294666_294851"
                     /protein_id="allorf_294666_294851"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIVLTDNRCTDVPRGRPRGADALDFSRAVVDGSHIRALKGAPRQG
                     EAPLGPGGFEGSLQHC"
     CDS_motif       19608..19706
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MIVLTDNRCTDVPRGRPRGADALDFSRAVVDGS"
                     /locus_tag="allorf_294666_294851_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       19707..19793
                     /prepeptide="core"
                     /locus_tag="allorf_294666_294851_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="2866.2"
                     /monoisotopic_mass="2864.5"
                     /core_sequence="HIRALKGAPRQGEAPLGPGGFEGSLQHC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIVLTDNRCTDVPRGRPRGADALDFSRAVVDGS"
                     /leader_location="[19607:19706](+)"
     gene            complement(19794..>20796)
                     /locus_tag="B4U39_RS38835"
                     /pseudo=""
     CDS             complement(19794..>20796)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021754435.1"
                     /locus_tag="B4U39_RS38835"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS30 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RFLTRSDRLHVADRLRGGGDGPGH"
     CDS             complement(20908..21096)
                     /gene="allorf_295966_296154"
                     /locus_tag="allorf_295966_296154"
                     /protein_id="allorf_295966_296154"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSPCPKPGGQGLRRSLQHLFLRGVVFEIRMDRAKALGGRRRLVRE
                     REECFRLVDQGYGNTEA"
     CDS_motif       complement(20983..21096)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSPCPKPGGQGLRRSLQHLFLRGVVFEIRMDRAKALGG"
                     /locus_tag="allorf_295966_296154_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(20908..20982)
                     /prepeptide="core"
                     /locus_tag="allorf_295966_296154_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.80"
                     /molecular_weight="2935.2"
                     /monoisotopic_mass="2933.5"
                     /core_sequence="RRRLVREREECFRLVDQGYGNTEA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSPCPKPGGQGLRRSLQHLFLRGVVFEIRMDRAKALGG"
                     /leader_location="[20982:21096](-)"
     gene            21137..21442
                     /locus_tag="B4U39_RS38840"
     CDS             21137..21442
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (68-83). E-value:
                     0.001. Score: 10.6. Matches aSDomain:
                     nrpspksdomains_B4U39_RS38840_PKS_Docking_Nterm.1"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1164: transposase
                     IS3/IS911 family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /locus_tag="B4U39_RS38840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_237297308.1"
                     /transl_table=11
                     /translation="MKHCPAEFKADAVTLYRSRPGATIKSGAADLGVNTETLRIWIRAA
                     DGRRHGAHLAPPAAAQAGGDAVQAELAAARKRIRELEEERDILRKTARYFATETRW"
     aSDomain        21341..21385
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B4U39_RS38840_PKS_Docking_Nterm.
                     1"
                     /evalue="1.00E-03"
                     /label="B4U39_RS38840_PKS_Docking_Nterm.1"
                     /locus_tag="B4U39_RS38840"
                     /protein_end="83"
                     /protein_start="68"
                     /score="10.6"
                     /tool="antismash"
                     /translation="AELAAARKRIRELEE"
     CDS             complement(21530..21628)
                     /gene="allorf_296588_296686"
                     /locus_tag="allorf_296588_296686"
                     /protein_id="allorf_296588_296686"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPSDSWWTLRIRAAIPASTACRVARAAAVRRQ"
     CDS_motif       complement(21575..21628)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPSDSWWTLRIRAAIPAS"
                     /locus_tag="allorf_296588_296686_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21530..21574)
                     /prepeptide="core"
                     /locus_tag="allorf_296588_296686_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.60"
                     /molecular_weight="1510.8"
                     /monoisotopic_mass="1509.9"
                     /core_sequence="TACRVARAAAVRRQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPSDSWWTLRIRAAIPAS"
                     /leader_location="[21574:21628](-)"
     CDS             21661..21855
                     /gene="allorf_296719_296913"
                     /locus_tag="allorf_296719_296913"
                     /protein_id="allorf_296719_296913"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTRAARAVDHKRVARIMRTSDSRESVCAAGTARPVADQADGRGTD
                     AFRPRRGRPGAAPCAGGPA"
     CDS_motif       21661..21747
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTRAARAVDHKRVARIMRTSDSRESVCAA"
                     /locus_tag="allorf_296719_296913_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21748..21855
                     /prepeptide="core"
                     /locus_tag="allorf_296719_296913_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.80"
                     /molecular_weight="3397.7"
                     /monoisotopic_mass="3395.7"
                     /core_sequence="GTARPVADQADGRGTDAFRPRRGRPGAAPCAGGPA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTRAARAVDHKRVARIMRTSDSRESVCAA"
                     /leader_location="[21660:21747](+)"
                     /alternative_weights="3415.7"
     gene            complement(22088..22792)
                     /locus_tag="B4U39_RS38850"
     CDS             complement(22088..22792)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B4U39_RS38850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_079408354.1"
                     /transl_table=11
                     /translation="MNQDEDLAAALQQAVAGLLVEPAPVETVVRLGRRMRRRRQATLST
                     ALAAAVLIPASAVAALSLGSFGSRTPTVPAASAAASAQVQVVGPGEKVALGRNNMLWLT
                     GQGLFLVTPKSSGTAKQSVLNAAEVPSGKISATASGGASGTLYTGIYRGPGKASRITVA
                     IGSRTLNTQVITLAGSPGWAAFYADDTQAGAIGMPAPTITVQAADGTILASMTKQAQLT
                     SSPAIDLGRAVT"
ORIGIN
        1 tcctgcagga gcagtgcggc ttcctgcaat cttcctcggt caataaggaa ctcacttgtg
       61 aggatctgga gatcgcagag cagctgcgct tctgcggatg tgagggcctc ccggtcgccg
      121 agggcgtagc gcagcgttcc cagcaacgcc tgccggtccg tgtgctcccc ggcccgctct
      181 cccaggtcca gggcagcacg gaggcgtgct gccctggaca ggggagtccc ggcttgcaca
      241 cccgccgcca gtcgaagggc tctttcgtgg tcgtgctcct ccgccgactc gagtgcctgg
      301 cgccagcggg cgacatcgac tgttttcgtc atggcatcct cacttctcgc agcaggtgaa
      361 gggcaacaca ttgtccgcgg acgcggtgat gcacggcact cgtcgaggac tgccggcgct
      421 gcgcatttcc aaaagcccat cagacatcgt ttgaaccgag ccgggcatgc tccttcgcgc
      481 tgcccaggtc gcccggagcg gtgtcctcgg ggtcgcccag gttcgcagca cgtggcaggt
      541 gggtggagag gcgaagagcc agcaaggcga taagggcgag aaccgcgatg caggccatga
      601 agtgcatgcg cccgtagccg ccgtccagca caatgccggc tgtcaacgta cccacgaaag
      661 cgcccagggt gaatgcggaa gccgtcaggc cgttgtaccg gccgcgcatg tcgtccgggg
      721 ctatggcatt gaccaggacc ggagcggtcg gagccagcag cgtctcgccc acagcgaaga
      781 cggaggcggc cacgacgacg agtacgaggg cccaggcgcc atccacctcc gtgatcagga
      841 tgagcgccgc ccatgccgcg ctccagagca cacagagcac cgcgatgagt gacgtgcggc
      901 ggcggccgcc gatgtatcgc aggacaacaa cctgtgcgac aacgaccgtc accgcgttga
      961 cagccgcgaa gactcccagc aggccaggct gaaacccctg accggtgaga taggcgggca
     1021 cagccgagtt cagttgggca tacccagccg tcaccagcag aaatatgatg agccacaggc
     1081 gcagaaacgt ccggtcgcgc agcacggcgc ggtagccccc acccgtaccg gcgccgggag
     1141 cttccgatgt gggcgtagtg gcaggtgcca ccaggcggat gagccacagc gcacccgcgg
     1201 ccaaaaagaa ggtcagcgtg tcgagaagga agagagcgac gaaactgccg ggatcctctg
     1261 actttgtgac catcacagca agtagcccgc cgacgcccag tccgacgttg agtgctgcat
     1321 ggcgcatggc gaaggctgtg gagcgcatct cctcggagac cgtggtcgcg atgagcgcgt
     1381 cctgcgccgg ccacgcgatc ccgcccccag cacctgtgac cactacggct gcgatcgcct
     1441 gccagaattc ggtcgcattg gccagagcca gaactccgaa gccttcgacc actaacccca
     1501 gtgtcagggt gcgacgaaac ccgaagcggt cgcacagtac gcctccaagg gagttccccc
     1561 cgaacgcgat cagagttgac acggccatga ccagaccggc ctgggaaagg ctgagacctc
     1621 gcacctgatg gagataaaaa agctcgaagg gaagagtcag ccccgtccca accgacgaga
     1681 tggttacgac agccagaacg ccccatgcga ctcccgggag agccggaatt accgggaatt
     1741 tcatggaaga atcacgcctt cttaggtttc gaagccgcag taccctagct cagtgggtga
     1801 agaaaattcg cagcctctgg gaaactcgca atagataacg taggtagtcg ccatgtccaa
     1861 aatttttagg acccggcagg gcgacaaaac ttaaggtgga ccttgatcgc gggggccccg
     1921 cgccgcccag aaaatgctga acggcgcggt caccaaagag ggggctacac gcggcgcgtc
     1981 tacacgacaa cctcactgtg gttatggagg tgcaggccgc gctgcggcgc tacgccttcc
     2041 tcgactacaa cctcactgtg gttcttgacg ttcaggccgc gctgcggcgc tacgccttcc
     2101 tcgactacaa cctcactgtg gttcttgacg ttcaggccgc gctgcggcgc tacgccttcc
     2161 tcgactacaa cctcactgtg gttcttgacg ttcaggccgc gctgcggcgc tacgccttcc
     2221 tcgaccacaa cctcactgtg gttcttgacg ttcaggccgc gctgcggcgc tacgccttcc
     2281 tcgaccacaa cctcactgtg attcatgtgc aggccgcgct gcggcgctac gccttcctca
     2341 accacaacct cactgtgatt catgtgcagg ccgcgaaggc ggggcgtgtg gttcgtgttg
     2401 gtcacggggt ttctccgttc tgtcggtgca gcacatatat tgttacggca tccgactcga
     2461 gtctttggaa gtctttacgg gcgccactgc ggaatcggtt cgcgatcacc tcaatttctc
     2521 tgcagcgact cgatgtaact gtccgaactg ttttgagcga gtaaatgtga atgctcatcg
     2581 gaaggaaagg agtgtagcgg cgaagcgcct gcgaccaccg gccccgtccc ggttgccgac
     2641 cttgcgcgcc agtttcacct cagccgcggg cgcgtaaaca cagcggaggc ggacgaggct
     2701 cgtgggtctc acctcggccg ctttgcaaaa gccaggcgca gtggggaacg gggacccgac
     2761 gagcagggcc ccgataagcc cctccggact tggtggcagt gtcaggtggt ggggattcgg
     2821 gcccagtgtg tggtgtggcc gttggtgtgg gtgtgggtgc cgtgggtgtc ggccagggcg
     2881 ttgatgacgg cgcggccgcg gccgtgttcg tcctctgtgc agctggtggt ccaggcgccg
     2941 tcgtgggtgg cggggccgcc gtcggtcacg ccgatccata cccggccgcc cgtgtgttcg
     3001 gggtggatgt gcagggtcag gggtgccagg gcgtgttcca cggcgttggt gaccagttcc
     3061 gaggtgacca gcagggcgct gtcgatcacc gggtcgggga ggtcgtgggc tgcgagcagg
     3121 gtgcgggcga tgtgccgggc gatggtcggg gccgttgtgt cgtgggccag cgtgcactcc
     3181 gtgatgccgt ccgtgacgcc cgtcaccggg gccgccgtcc tggcgggggc ggggagcggg
     3241 gccggctcgt cgggccacag cgcgagcaga tcgtcgagct gctcttccag ccggtcttcc
     3301 acggtcgtcg tcatcgctgt cacttccccg aaattcgaat cggtgcactt gcggtaccca
     3361 ccacgctgca cccggggtgt cccacccgac tgtcaccccc ctttcacccc gataacgaac
     3421 caaatccccc caagccggat caggcgcgaa cagaccacca ccgacaacat cccggccgac
     3481 cgaatcagct gccaagcagg ggactggctc cgaccaggtt tggccctgct cctggcggtg
     3541 aacacgcgac gcggggtcaa ccaccttctc gatccgatct catgtccgat cggggcgact
     3601 gtttaccgag gttgcggcga gcctcggtcg ccgtgaggga cagcgcgtcg gagaggaggc
     3661 tgcggcaggc tggaatccag cggagatcgc cggagccgga cggggcaggc tgcggaatct
     3721 cagcgctgcg cggcggcggg tggctgtacc tgcggcgatc atccacgatg acgaacgcgt
     3781 cgcgggcatc ggtcttggct tcacccggac agagatcggc gatccgccgc atcgtcagcc
     3841 ccggcagata gccaccgggc agcccatgtc cctcgcgacc gtcagcggca gagcgccgat
     3901 ggaggccggc tggtccacga cgaccacgag cacggtcccc gtgcttggcc tgccgtttcc
     3961 cgaggacctc gcggagcttg ggctcgctgt tgggccagcc gtttgtcgaa ggccttcttc
     4021 ccggccggtg tgacggccgt ggtgtggtgt tcgcccctgc cgacgcccag gccgaggaaa
     4081 gcgccgatgg cactcgtgtc gatcatgcgc gtcctccggt cgtcttcttc gcccggccgt
     4141 cccacggcac cgatcgcccc atccacatca cgaacagcct cccgacctgt gaaaaggccg
     4201 gtggtcatgc ccctgatcag ccgactgtcg atgcccccgg agccggtgac accaccccaa
     4261 gacaatgcga tcgacacggg gagaaggcca tgccaactcc gtaggccggg cgccctctta
     4321 cggggccaaa acggtaatgg ggactcgtct cagcgggact gcgttgtccc agtattgagc
     4381 agtgcatccg accggcagcc gaatgccgaa ctcgtccgtc aggacagcca gttcacgaca
     4441 tgttttgaca gccgcggccg gaatggagga tcacggggcc gggtggacgg tgggtgtggc
     4501 aggcggtccg cggtgcgccg gcgacaagct cggttcgcag gtgatcggcg gtcgcccagc
     4561 cgacgacgcg gcggaagcga tgtcgatcac ggtagccgaa cagagccgtc cttctcgggt
     4621 ggcgaggtag gcgatatcac cgcgccagta ggtgtcgggg gccgagaaat cgggctggaa
     4681 gtcgcgagca cgggtgcggt gtcgttgcct gccggtcggg cggctgcttc atccggcggg
     4741 ccacccgacg gcgtccgcag tcctcgcgct tcaggacggt gtaaacgcgt ggaggcccgt
     4801 agtgctgcga gaaccctgtt gaacagcggt gatccgttcg gtcggctcgg cgtccgcgtc
     4861 gcacgaaagc cacgggaggt gcgccgggcg aataggcggt cggggagact tgaggagctc
     4921 aacgcccgtt tgacgttgtg acccgaggtt gtccccgact cgatgaacgg gtgtgcaccg
     4981 ggtctccgcc cgaagagccg ccgcgcgctt tgagcgtgtc gacgtcctcg cgcggcctgc
     5041 ggttctcccg ccacagtgca gccggttcct cgcgttcgct gctgctcaag cacgctccgt
     5101 tcgccgacat cgacctcgga agcctttctc accccgcgcg caccgcggtc tcggtcagct
     5161 cgaaatccct ggcggcctga ccggccgacc ggtcgccccg ccgacacagc tcgacgattt
     5221 ccgccttgaa ctccggtgtg aacgagcgcc gaggaagcgc tctcttcttc tccatgctcg
     5281 ccatgacgaa catcatcctt ccgaggccga agcccctgat tgcagatatc cgtcaaagcg
     5341 gagcaggccc acgtctccgt ccggccccca cgcctggcta ctcgactata tgcagagcga
     5401 tcagccgaac aggtcgcgta tccgcaacgt gcgggtgcgc ttgtgcttca cctttgcagg
     5461 cagcagcggg ccgggcgcgc gcacgggcgg ttgccactgg gcgcgactcg cggccaagaa
     5521 gtcgttccac gcatctgttt ccgtcggccc gtggcccacg acatctgtgc cggagcacgt
     5581 gacgagaaaa ccattcgggg tcagccgaac cgacacacct gtatccgtca tgggtacctc
     5641 catcagtgcg tacagcgcag ctcaggggat ttcagtgtgc caccaccttc atcgaatacc
     5701 accttcaccc ttcgggacct ccactcggtc agtggctgcg cagtgccgtc gacgatcagc
     5761 tgcgagggcg gcatcctcgc agtgatggtc cgagaccgtg tgtcattatt cgcccctgtt
     5821 ttgcccgcgt ccgagagggc cgcccaccgg tgagaatcag aggtcgcact cggccatccc
     5881 gcctggcctg ccggagttca cgtatcggct tttgaggagc gtcgtcccgc gacgacccga
     5941 gacgatccgc tcgcgatcgt cgctgaaccg tggtggtctt gactgcttgc gcttgcccga
     6001 gacgaacgcc cggctcccgg ggcgtccggc ttgggggcgg cggaccgggg tctcgacctg
     6061 tcgagctgcc gctcaatgtt cttcgtctcc gcgtaggcga acacgtcttc cccgtgcgca
     6121 ggcgcaggcc gaccggtcgg agacggcgaa gccgcgggtc gcgagcaaga gccggacctt
     6181 tccgatcgct ctgcctgtcc gagacgtggt ggaaggagat ggtcgccgcc ctggacaccc
     6241 tcgccgatgt cccaccgccg gcggaccgcg aggccgtaca cgaggagtac ctgcgccgcg
     6301 tcatccccca gttcaccggc caccaggtcg gggagatcat tacctggagc accgcccacg
     6361 gcgacctcca ctacggcaac gtcacccgcg ccccgcacat cctggactgg aaaggatggg
     6421 gccgcgcccc ctacggctac gacgccgcca ccctgtacct gtacgcactg ctggtccccg
     6481 ccgcggccgc ccgcatccga accgagctcg ccccgtcctg gaccggcccg aggcgcgccg
     6541 gcccactgac cgtgtgcgcc cagatcctcc aggcccagga ccgcactgcc ttctacgccg
     6601 agctcgacag ccccgtacgc gagcagtttc cccacctgta gcagggctgc tgcacaccgg
     6661 ctgccgtttc cactaacccg cgctgatggg agcggatcgc cgagcgaaga ggcgcgcggt
     6721 gcgaccaagc gggcgccagc ggtgaccgac ctcgcatcac ggtgttgaac ctgtatgccg
     6781 tccagccgca cggcaaaggc gagcacagcc gtttccactg gaaacgggcc cggcgatcac
     6841 cgagacacgt ccggccaggc gagtttccca ccgcagggac gtccgcgcgg tgggcgagga
     6901 gttgtgtagg catgagcagc tgtacgtgcg acttcggcgt catactggga ccggcggtga
     6961 tggccgccgg cttccttcgc agcattcagg cccgggccga cggtaatagg cgccggggcg
     7021 acgacgggac cacccgtgat gtgctggaca tcctgtccgc cggctggagg gcggccagcc
     7081 ggtcctgttc gagttcgcct actgggccga cgagctgcat gctcctgtca cgcgactgcg
     7141 agaggtggtg gcgtggctcg tcgagcaaat cgttcacaga ccgcacagaa cgggcatgtc
     7201 gaggcgggcc atacggggcg tcggagtgcg gcccccgtcg cggccctgat ggccgaggcc
     7261 gcactccgta cgtcgaaact accgggtacc gaatcgagcg cggtagccgt tttcgctggc
     7321 cggacaggtg actgcggagc atccgggccg ttgtgtcgag cgctcatcgg gacgttggcc
     7381 cctccgctcg gcgaccgatt ccggtgacgg cttgaagtag cgacggacat tctccggctt
     7441 cttgtgccgc gacttcgcca tcagcatcag aagggagacc ccttgctcgc agaggtgagt
     7501 cagggaggaa tggcggtagt cgtgcaggtc acagccggtc cgcgcaccgc gagcctggcc
     7561 gtaaaaccga tccaggccga tgtccggaca gacatcgcgg aggctaacga tcttgcctgg
     7621 ccccaggcgg cggtgggtgg cgaaacacag gaccgcgcgc acgtcccttc agcagccggg
     7681 gcagcagtcg ggcggtacca gcgtcccagg gtctccagaa cgtagtcctt accgacctgg
     7741 ccgcgacggc gggccttggt ccgggcaccc tccgccttca ccggacagcg gcgcccggcg
     7801 aagtccaggt cctcgttcat gccgaggatc tcctccgccc gcccggatgt ctcgtagagc
     7861 atccgccaca gcgtcttctc ccgcaggtgc acctcgcgcc gggcggtcag ccggtcgatg
     7921 gacatcttcg agcgggcggg ggtctcgaag tccggcaccg ccagccgcta cgcccaggcc
     7981 gggaccccag ggccctcata gccgcgctcg cggcaccagc tgagccagga ctgcacccaa
     8041 gcccggcggg agttccaagg tgttgaccgc cggcttcctc cagagcagtt cgagggcttc
     8101 gccgatctcg tcgtctgcga ccgacgccag cggccggccc tcgccgatcc gctcggcggt
     8161 cttgccgacc ccgatcgatt agttcctgac cgtgttcggg ttgccgagcg agtcaaggaa
     8221 cacgtcggct gccgtccgga cgatcaaagt cttcgcggtc ggcagcagct gcacgacggc
     8281 ggacacgctt tccccttccc gtagataaca gggccacttc gtgtagcggc cggagaatgt
     8341 caccaaaggt gacggatcaa gctaccgcag atattgggtg ttatctgtgg gacaacttca
     8401 ggcccgtccc gtagccagag actcggcagc cgtccacccg gcgcgactgc tagcgcacga
     8461 tctgacatgg atgttcctca gtcccgacta ctcagcaact gaaacggcaa ggtaaatccg
     8521 tgacactccc aacgccctcc gcggcctcaa tggccgtttg ggtcttttac gacaaagccc
     8581 gtccacgtct tgcgaagtcg gtcgccagct gtcgggtcga ctcgctggac agcatgcata
     8641 gtgtgcgagc gaaagatgac caggcgattg ggacggggaa agatcgatac ggggtgggtt
     8701 gcagagtcga ggagatcaat gccgtcgact ctctgcgggg cttcctcgtc aatgagtgtg
     8761 agcccccctc cccagctggc gctccaattc ctatgtgcga agtagacgta ggcgcccacg
     8821 cggttgtcgg caccatcgtt gtgccatccg agccgagatt ctgcagggta tccccggcct
     8881 gagagggtca tacacagggc atctgcagat gtggccgccc atattcccag gcatacacag
     8941 acctgctcct ttaatatgcg ctgccaaggg ggcgtgccgc tctcacttcc acgcaaggag
     9001 ctctttcctc catcgccgag gtaggcaggc ccatcgtaga tagggtcgat actgctcagg
     9061 accggattaa gacgcaagtc atcaaatgca tccgcggcgg cgctaaattg cttccccgga
     9121 aggaagtcgt caataaccgc aaaacgaaca ccttgagaat gcattcgagc agtcggggtc
     9181 agggtaattg tcgatggaat gatattctcg cgcatttttc tcctctatcg accggtcatc
     9241 ggcggcagtt gccgcgcttc tttgtctcag tatcgcggac tctatccaga cgtcgaatat
     9301 tacgccgttg cgactgattc cgcgcagtgc tggaactcaa ctccctgcaa gtcggcattt
     9361 tgaagcaaac cacaacttcg caagagatcg accttcgttc cagctatacg aggctatttc
     9421 tcaatgcata accatcgtct tgcgtgcgga catcactgta gcgcgagttc tttctcgctg
     9481 gcagatccag tcccgtgcgc cgccgctggg ttgccggagg gcaacgctgc acggatgagc
     9541 acagccctat cgccgtctgg gaggcccctg cgaacgtgaa tcgaaccggc gactgcctcg
     9601 tgccatagat ccgattggac aggttctgcc gtactggaga gtgacaataa cgaagggatg
     9661 ggcggaggtc ttgcccggct tccgaccctg aagtgtagga ggaactcgtg ccgcaactta
     9721 tgactgttga ccctgaagct gttatcgacg catggcgtcg ggatgaggcc atgttcggac
     9781 tggagagccc ggctggggca cgtttcgttc tcggtgttcc gtctgttgat gcggagttcc
     9841 gtggagacac gtgggaaacg tgcgcgccga catgcaccga gcccgagtcg gttccggaaa
     9901 actcctgatg tgagtgaagg ggaagggctc ccccttcccc ttctgctttt caagctggaa
     9961 gtcgggttca atgaaaaact cctcagcctc tgatggcttc atgccggccg ttgcggttct
    10021 ggtcgattct ttcaacgtgg agctgagaga atatctcgac aatgtgtctg gactggagca
    10081 atatgaggtc gagatttttc actcggcggc gtgtaaggat ctctcaagta tctttcttgc
    10141 aagactgacc ccgctgctgc tattggagtt gaacgcagcg cgcttgcgtg ggcagctcac
    10201 cggagatacc gcagaagccc gatggcgtag ttttctcggc cgctgcagtg caggtgaatt
    10261 ctggccctac gcattcgaag tctatcccgc gcttcctgga cgactccgta gagtttccag
    10321 gaacgccctc gagtcttgcg tcgagatggc gcagcgtttt gtgctcgatc gtgacgctct
    10381 aaggagcatc ttcggtgcac tgactctcac cgatgtcgaa acaggccttg gggacggcca
    10441 ccgcggtggg cgaaaagtgg ccagattcat attcggtgct actagtgtcc tgtataagcc
    10501 acgacccctc gacgcagacg cggcattggc acatttgttg gatgacctgc agccggaagc
    10561 tgaggactcg tggattcgag ttcctgccgt ctacacgcgt tccggatacg gttgggccga
    10621 gttcgtggaa cacgcatatt gcactgactc ttcagaagag gctgatttct atcgcgccat
    10681 gggtgcgtgg gtcgcagtca tggtattgat ccggggaact gatcttcatt tcgagaacgt
    10741 gattgcctgc ggcgcgatgc ctgtggttgt ggactgcgag actttgttca ctcctccccc
    10801 cactcctttt aatcatggca tgagtcttgc atcggtggag gcgcggaagc gaatgcggca
    10861 aaccggtttg acgaccggac ttctgccatg gcgtagtccg cagcccgctc caggacgtgc
    10921 tggggtggat ctctctgctc tcggggcatt gcctgaggaa cagccggcgt tcgccgttcc
    10981 aatggtgcag gggaatgggt cagacgacgc tcggctggtc gtgcgagacg cgaaaattgt
    11041 gagtggccgc aatcatccgg ttttggctcc tcaaccggaa cggtacaagg cagagatcat
    11101 tgacgggttc cgtgactttg ccgaccgtat tggggcgctg gatcgcgcgg gtaagctgga
    11161 aagcgcactt cagcgctttg ctcgttgcga agtgcgcctg gtgacccgag cgacgagggt
    11221 ctactactcc atcagccggg cgttgtggca tccgtcgtcc ttgcgcgacg agtgcgccgc
    11281 ggtacgtgaa gtggtcgacc tcctggtgca gcgcagagaa aaagacctcc acgcctgctg
    11341 cgaatcgggc gaagtgcgtg ccgaaatcga ggaactcctt tatggagata ttccaatata
    11401 tatctatgct cccgaagagg gcatagtagc tggtgcgggc cgattgccta accctgaata
    11461 tggaaaccag ctggatagtg ctctctcagg atggcgaaat attgacctgc cgttccagga
    11521 ggcggttatc aatgcctctt tcgcaggtgc tgttcgcgat gcgcaccgag tggcgatgac
    11581 aggtcaggca agctcgactg gtctcattcc cgcttccact gaacagaatc cccagctcaa
    11641 ggattctctt agaaaagcgg tggagcgtct cgcggccgaa gccatccgcg ggacggacgg
    11701 gtcggttaca tggatcggtc gcggattcga agattcaggc agcccttggg ggcctgtttc
    11761 gatgaatctg tataatggcc aagccggtat cgtattttcc cttgctgcat acgaacaagc
    11821 tgtcagaaat gggcatgtgg aggcagtttc cggtctggat gaaatagttc gagctgctac
    11881 agatgttctt gtcgcagagc aagaaaaaag cgtgacttct gggcgtgcag gatcgggcgg
    11941 gtacaccggt gcaggtggag ccttgtggac ctggcttgca cttcacaaca tcacacagga
    12001 caacagaatg ttgaagtgcg caatccgtgc agccgaaagt ttccatggcg ctcccgatga
    12061 ggatgtttat gatcttctaa atggcgtagc gggcggaatc gtgcctctca ttggtcttgc
    12121 cgagctttgc aaagacgacg cctacctcga tcaggcgact gccctggcag aacttgtttc
    12181 gcaaagcgct ctgcctcaag aaataggcgt gtgctggccg tcgaacctgt ctcgtcgagg
    12241 agtgggtggc ttctcgcacg gagtaacggg cataggatgg gcgcttaagc gtctgggtat
    12301 ggcagctcga gatgagaggt ggggcaacct cggcgaccag gcattcctct tcgaggagag
    12361 tctttaccag cccggcaagg ggtggaggga tttgagatac ctcaacgctg cctcatttca
    12421 gcacgcatgg tgtcatggct cgaccgggat tggtttagct gcactcgatc ttttcaagca
    12481 aactggcagt gaagaatatc aagagaggtc ggttcgcgcg atcgcacatt gtgcaggcga
    12541 gagtcggaac agtctgggca actctctttg ccatggcctt ttggggaact tggaatttat
    12601 ttaccgaatc cacgaaggca aaattgcgaa tggatccaac ttcatagacg agatggaaat
    12661 ttcgctggga ttagagataa gcagagtgct gcatgaatcc ggccccctca tcgacccggg
    12721 gctaatgaca ggcatgtctg ggcatatcta ttctgctctc agtgcggatc ggcgaatatc
    12781 actgccttct ccgcttacgc ttgaagtccg ctaagggctt gcagggaatc aaggcggtgc
    12841 tttagtactg gggctcgttg gtgtggtatg cgcattccgg acgagactcg tgaccaactt
    12901 gctgtgaagt ttgcagtgtt ggacgagcgg cagcgtcggt tgttgatcgg tgagggcctc
    12961 ctagcctggt gtggattgcg acacctgcat cggcggccag aaaggtcctt gtgccccacc
    13021 gtaattcacc cctgaaaaca tcatcttttc gtgtccggta agtgcttccc tctaaggggg
    13081 agggggcatt gcagctcgcc gcagatcgcg gatcaagaga tgtggaggca agtcaaatgg
    13141 ggaattgtgt acacttaggg cagttgggta atggcgcgta aaaattctgc tgctaaattt
    13201 aaaggatact cacgcttcat tccgcggcgc agtccaattt ccgatgcctc gcctgaaaat
    13261 agaacgtcgt tgttcggggg gaaattattc tatgacctag ggtatgtgcg ccatgagggg
    13321 gccagtcatc ggatttcgtt cctgcaggtt gtctttcgtt tgccgcagat gctggggatg
    13381 atcgtcagac ttgcgtgggc agccgatcga cgcgctttgg tgactgtggt cgcggcggag
    13441 ctggttcggg gggcggcgct ggctttcggg ttgttaacgg tgaacagggt gtttgtttct
    13501 ctgcttgctt ccggtccgac gcccgataag ctccacactg cgcttccacc gcttatgctg
    13561 atgggggctg ctgctgcaat cggggtaggc gcgggctcgc tctccacggc cgcggcgggg
    13621 cggctggagc cgaaggtcga acgtacgacg actgtgcaat ttctggaacg ggcgatccgg
    13681 gtagagctgc tggcaatcga agatccggag tttcaccgac ttctggactc tgccgagtac
    13741 ggcacgcggg ccgccaggca gatgatcggc cagaccgtgg cggtagccaa tgcctgcctc
    13801 actctggcag ctgccggggg cgtgctggcc gtgctgcacc ccgctctgct gccgcttttg
    13861 gcgctcattg ccgccccgaa ggggtgggga gcggtccgta ccgcacgccg gcggtacgag
    13921 tcgaccctcg cgtgggtgca acacgcacgc gccagcacgg tcgttgcgaa actccttact
    13981 gacccgctcg tggctccgga ggttcgcgtg catggcgcgg gctctttcct gctccggcac
    14041 ttcgagggca tgtccgccga cgccgaggcc gagcagacac gtctggctcg aagccaggcc
    14101 agcaccgatc tggccgccgc ctctttgtcc ggcatagcct ccgccgtggc ttacctgacg
    14161 cttggcctgt tgcttaactc cggcatcatg gatctcgctg tcgcagccac cgccgccctc
    14221 gccatccgat ccggcgcagc gaacatcacc acattcgtca ctcagatcaa cggcctctat
    14281 cgcgaagcac tcttcctcca agacctccag gaggtgtgca tcgaaggcga tcgccgcgcc
    14341 ataccggagg ggggcacggc accccgagct acaccagaag tcatacgact gcacaacgtg
    14401 agcttcacgt accccggcag gggaagaccc gcggtcaaca acgtgagcct gaccattcgc
    14461 cgcggccagg tcgtagcact cgtgggggag aacggatccg gcaaaacaac catcgccaaa
    14521 cttgtagcag gcctctacga gcccgacgac ggaaccctca cctgggatgg cacggatgtt
    14581 cgagagctcg accgagagca ggtgttctcc aaaatcggac tgctcacgca ggactttccc
    14641 cgctggccct ttaccgccca ggccaacatt gccatcggaa acccccagtt acctgtcgaa
    14701 acacacgctc tcactgcctc agcccactac gccaatatcg accaaatgat caaaaacctg
    14761 cccaaaaaat gggacactct cctcgctcgc caattcactg gcggtgtaga actctccgga
    14821 ggtcaatggc aacgccttgg gctggcccgc gcccactacc gctccgcgcc catattgatt
    14881 tgtgacgaac ccacttctgc ccttgaccca aaagcagaaa tcgaggcgtt cgaaaaaatc
    14941 cgcgccctca ccgaccaggg ccacacaatt gtcctcatca cccaccgcct tgcatccgtc
    15001 cgtcacgcgg acaccattta catgctcagc aacggacagc tcatcgaatc cggaacccat
    15061 cagcaactgc tcggccaaga gggccgcttc gctgaactct tccacctcca agcaaaccaa
    15121 taccaacccc ctgaccaccc ataacgaaat gatctttggg ctggttggat ggctccggga
    15181 atcttgatct gggggtgtgg gatggctcgg cggaagccgt gggaagtgga cggtgagtct
    15241 gggcggtggt cgagcggcgg gttcgtcatc cggggcggaa gcggcatccg gaccggctgg
    15301 tgttccaggg caccctgttc gttttgcaca ccgggatcgc gtgggaacat ctcccgcagg
    15361 agctgggctt cggatcgggc atgacctgct ggcgacgcct ggcctccggc ctcggggaac
    15421 atcggtacag cggttatcgg tgagaatgat cttgttcagg gcgtgagcgc gctgacccgg
    15481 ttctcgtact cgcgacgggc cttgcgctgg gccggaaccg cggggacgcc ctgagcgccg
    15541 tcgagcggct ggcagtgggt gaggagctgg cggtgtacgg cggggagggc gctgacgcac
    15601 agggtgtagc cctggccgcg ccgtacggtc atcccctggt cgagtgcgac ccgctcggcg
    15661 ggctccagct ccgtggtgtg gaggtagtcg gcaaccttgc ccggcatgtc gagggtgacc
    15721 ggcagctccg gggcgggcgc gtcctcctgg ctggcggagt ggtcgggcag gaggtcggcg
    15781 atggcggtcc ggatcgcgcc gcggctgacg ccgtggtcac gggcgagagc ggcgatggag
    15841 cagccttcca gatacgccgt gcgtacgtcg gcggtcttcg tggccgcgac ggcggggcgg
    15901 cgcccgccct tgttgccctt ggcctcggcg gcgcgcaggc cgtcgtaggt cagctcgcgc
    15961 tggaggtcgc gttggagttc gccggcggcg gcgagggtct ggaccatgaa cttcacggtg
    16021 gacagcagtt cgccggtgcg cgggtggcgg gcggtgaggt ccatggcgga gaacgcgccg
    16081 tcgtggatgc gcagggcgag gcggtcgcgg tgcaggacgt cgagcacgtc gaggatgtgc
    16141 tggttgccgc gcacgaggcg gaacatctcg gagatgtgaa cggtgtcgcc cggccgcgcg
    16201 taggtgagca gttcgccgaa cttcgggcgc tggagcgggt ggaggcggct ggaggcaccg
    16261 gggtcctcct cgaagacgac cgggtcctcg atcccggcct cggccaggac gaggtcctgc
    16321 cgggcggcga gcagaccggc gtcagtggag gtgccgcaga tgaagcacac cgcgtcgggg
    16381 cccgtacacc ggctcactcc tacacggcgc cgtcgtcgtc ctcgtccagc tcgatcgcct
    16441 ccgggtcgcg cagcggacgc agagcaccgg cgaccggaac actggccgtg aagctgtaac
    16501 ggcccagcag gttcaggttg cggtgcttga gcgggagagc cgagcgacgt cctcctcgcg
    16561 gatctcgtgt ccctcggagc ggagctgggc gacggcggcg tcgatgtact tcgtggtcca
    16621 cagcacgatg gcgttgagga ccaggccgag cgcgccgagc tggtcctcca tgccgtcccg
    16681 gtacgcctgg tggatggtgc cgcgcttccc gtggcacacg tcccgggcca gcttgtggcg
    16741 ggactcctgc acggtgagct gccggttcat ctgacggcgg taggcgtcgt ccaccgggtc
    16801 gaccacgcgc agcagatgct ccgtcttcgc gatccgcccg tactcggcga acgccgcacc
    16861 cagcgcggtc gggcgcccgt cgcggccgaa catgcgcagc aggtcgtagg cgcggacctg
    16921 gttggtgacc agggaaccgg cgaccttcag catgtccggc cagtgcgtga tcaccttgtt
    16981 caggttgacc cggttgcggc ccaggtcctc caccacgccg tagctgccgg tctcgactcc
    17041 gggcatcgtg gcccgccaga accgctggtc gtccaggtcg cgaaaccgcg ggctgaagtt
    17101 gtagccgagg atcttgacag gccgaacacc atgtcggagt acgacgcgtt gtcggtcgcc
    17161 accatctccg gcttgacccc gccgtccagg ttcagcaggg cgtccaggat gtgcagggag
    17221 tcgcgcgggg tgccgggcac gaccatctgc ccgatgcccg cgacctggtc gttgacggcg
    17281 ttgagccagg tgatgccccg cttgaacccg aagtacttcg gcgacggggc ggcgttgatg
    17341 gtgcgcaccg gcacctggaa gcgcagcccg tccacagagg cgagaagccc ctcaccccag
    17401 aaccgcacga tcgggatctc ggcctgggcc gcgatcaggg cggcgttcgt cgcggcgatg
    17461 gtgtcggcgc gcaggtagta ctggtcgacg tgcacgagcc gggaccgggt cagtgcctcg
    17521 tagccggggt tcaccactgg ggtcaggccg atgttgcacg cctcggacac cagcagcgcg
    17581 accatggagg tcggcaggtc cgtcatcagg gtcttgccgt cgccgagatg cacgaaggcg
    17641 tcgaggaacc cggtccaggc gttcacctcg aacagcaggt ccggcaggtc gatcttcggg
    17701 agcatcttct cgacccgccg gcgcagccag gtcagcgact tgggctcgcc gagggcgccg
    17761 agtttgtcga cgttcagctt cacccgcccg tcgtcctgca cctcgatgga caccttcgcc
    17821 gccggccccg cctcctgaag gcgttcggcg agctgcttcc atccggcgtc caggccccgt
    17881 accagctccg ccaggtgctc ggtgacgggc atgtccaggc tcagggccgc cagcacgtcc
    17941 tcctcgaccg cgtcccagtc cgggccctcc aagaggcggg cgcgcgggtt ggaccagcgg
    18001 tgcgacggtg tggcgaagac gtcgcggctg ttcagggccc ggtgcagctg ctccagcacg
    18061 cacaccacgt acgcgtcccg atccaccgcg ccctgcggta gatcggggtt ggcgtacacc
    18121 gccttgcgcc acgccggcgg caccagcttg tcgtctacct cgcgcggcag cagcggcttg
    18181 atacccacct tccgctgggc cagcgccgga agaccgcgca ccccggccag gacccgcttc
    18241 ccggcgctcg ccgcgtccag cgccttcgac tcgcccagca acgcgaggaa cgggcgcacc
    18301 gtggcgtacc ggttcgcgag cgtggcccgc atggcgacct cggccgagtt ctcgtcctcg
    18361 ggcaccaggg tcaccacggt ggccgccgcg ctcatcacgg cggcgcgtgg ggcgacctcc
    18421 tccacggctg cccagagggc ggccacgtcc aggtccgcct ggtgctcctc gcccagctcc
    18481 agctcctcga acagcacctt cgccgcccgc gcgagcaccc gtgacgcctt ctccagctgc
    18541 ggcagcgtcg acagccgctc cttctccgtc ttgcgcttcg ccgagttcag cagccgcgtg
    18601 gccatcagga cctggaacag gtccagggcc tcgtcgatcg ccttcgcctc caggtgccgc
    18661 atcaccgcgg tgagcatcgc cgtgcgcttc ggttccgccg cccgctccag tagcggcgcc
    18721 ttcgacccca gcgcgtaccg ggccagcgcc gccatccggt tcggggggat ctgcgacagc
    18781 ctcaacctgc cgagccggta cgcgccgatc tcgtccaccc gctcctgcgc gcgggcgaac
    18841 gccgtgcccg tcgtccgtgt cggtggctgg cgcagccgct ccagctccga gaaccgcgag
    18901 ccctccggcg tcttcagcgt cgccaccagg tccccgggta gggtccgcac ggcgggcggc
    18961 gcccacgacc gtggcgtgca ggcgtttctc cgcgacttgc cgcgcctccg acacctgccg
    19021 ggccagcacg gacaccccgg gcagcaggac ccggtgacgg cgcagccagc ccaccgcgtg
    19081 gtcgaacagc gccttcgggc cctcggcgtg cgtccacgcc cgcccgtgca ggaacgtacg
    19141 gaaccggcgg ccccactcga tgtcctcgta ggggtggtag ccgtaggcgt cccggatctc
    19201 ccacgcgtgg tcgtacagcg tctggcgccg ctccgtgtac cgcttgacca cggacgggtc
    19261 ctcgataccg agctgcacgg ccaagtgttc gaccaccgcc cacggcaccg cgagcggatc
    19321 ctccaggaac aggccgacgt accgcaccgt gcacatctgg agcgcgaacc cgagccggtg
    19381 atgctccgtc cgccgcaggg cgatcaggtc ccggtccacg tcatccagga agaagaaccg
    19441 ctccagctcg ggcctcgtcg gctcctcggc gaacgtccct tacgcctcgg cctgctcatc
    19501 actcagaaat tccaccggca cgagccggac cgtagccagc cccggaccgg gcccggaggc
    19561 gtttcaccga accccagcgg cgaagtggat cactgtgcta gacggccatg atcgttctca
    19621 ccgataaccg ctgtaccgat gttccccgag gccggcctcg tggagcggat gctctggact
    19681 tctcgcgggc cgtggtcgac ggctcgcaca tacgcgcgtt aaagggggct ccaagacagg
    19741 gcgaagcccc gttggggcct ggcggattcg aggggtcgtt gcaacactgc tgatcagctt
    19801 gctgtcagga gcgtagccag acgctcggct ggggtgtccc agccgagcgt tttttgtggg
    19861 cggctgttga gttcggcagt cgcggcggcg aggtgttcga tgctgtggct tgagaggtcg
    19921 cttccctttg ggaagtactg cggtagcagg ccgttggtgt tctcgttgga gccgcgctgc
    19981 catggggtgg ccgggtcgca gaagtagacg ggcatgtcgg tggccatggt gaacgcgccg
    20041 tggccggcta tttccgtgcc ctggtcccag gtcagagagc gtttgaactg tgatggcagc
    20101 gtctcaatgg tgcggggcag cacctggtgg aagtgttcgg ccttgtgtgc tccttcgggc
    20161 aggtggagga gtatcaggta gcgcgtcgag cgttccacca gcgtcccgat ggcaagaccg
    20221 gtggccgcgg ccgacgatga catcgccctc ccagcgcccc ggaacggccc ggtcagcgac
    20281 ctctgccggt ttctcgccga tcattaccat cggcgtcgcg aagcgcggct gcctggctgc
    20341 atgccggtga ggtttgcgtc gggtccggcc gtgcgcaacg cgtgaacgag ttctctgcgg
    20401 agctcaccgc ggccctggac gtatagcgcc tggtagatcg tctcgtgtgt cacacgcatc
    20461 tccaggtcgt cggggtagtc gcgaggcaac tgggcggcta tctgttccgg gctccagcgt
    20521 cgtgtcagac gctcctgaat gcagttccgg agtcgggagt tccggctgat ccttcccggc
    20581 ttcggccgtg gtcggcgtgc atcggaacgg gcttgagccg cgtagggccg gtaggcccag
    20641 cgcgaggtgt ctccacgcag cgggatgccg ttgcgtcgta tctcacggct gatggtggac
    20701 gggctgcggc ccggctcagc gtcaatggcc cggaccgtcg cctccccccc gtaaacgatc
    20761 ggcgacgtgc aagcgatcag accgggtcag gaaacggctc ggggcaacga gagccgacgg
    20821 tggatgaccc gacgggcgga accggtcctt agccatcctg ccgttgcgcc attcacgacc
    20881 ggttcgttcg ttgatgccca ccagtcgtca ggcctcggta tttccgtaac cctggtccac
    20941 gagccgaaag cattcctccc gctcccggac cagtcgcctg cggccgccca aagccttggc
    21001 ccggtccatg cggatctcga acaccacacc cctcaagaag aggtgttgca acgatcgcct
    21061 caagccttga cccccgggtt ttggacacgg agacacttgg atcttgatgg tccgggagaa
    21121 cggagtccct gtggggatga agcattgccc cgctgagttc aaggcggatg cggtcacgtt
    21181 gtaccggtcg aggccgggag cgacgatcaa gtcgggcgct gctgatctcg gggtgaacac
    21241 cgagacgctg cggatctgga tccgggcggc cgacggccgc cgccacggtg ctcacttggc
    21301 gccgccggcc gctgctcagg cgggcggtga cgccgttcag gcggagctgg ccgcggcacg
    21361 gaagaggatc cgtgagctgg aggaggaacg cgacattctc cgcaagacgg cccgttattt
    21421 cgccacggag acgcgctggt gaaccgctgc cagttggtga ggatcaccac cgccgtcacg
    21481 gcgtgaagcg gctctgcgac attctcggcc tctcccgctc gagtttctgc tactggcgcc
    21541 gcaccgcggc cgcacgggcg acccggcaag ccgtcgaggc cgggatcgcg gcccggatac
    21601 gcaaggtcca ccaggaatcc gacggcactt acggagcccc caggatcacc gccgagttcc
    21661 gtgacgaggg cggcccgggc ggtcgaccac aagcgggtcg cgaggatcat gcggacatcg
    21721 gattcgagag agtccgtctg cgccgccggc accgcacgac ccgtcgcgga tcaggccgat
    21781 ggtcggggaa ccgacgcctt tagaccacgg cgagggcgtc ctggggcagc cccgtgcgca
    21841 ggtgggccgg cgtgatcacc agtcggtcac agaaggcgag ttcgtacttc ggtcccgctt
    21901 cggcctgacg gtgacggttg cgcccgcgcc ggtcgtgagg ctcgccctcg catcgcgatt
    21961 tccatcgagg tccgctccca tcgagcaact cgccgaagtg ttggcgactc acggcgcaga
    22021 aggcaggatg agacaaggtc gcgcggccca cttcttgatc acactcgaag aacccgcgcg
    22081 gccatggtca tgtcacggcc ctgcccagat caatcgcggg tgagctcgtc agttgggctt
    22141 gctttgtcat cgacgccaga atcgttccgt cggcggcttg gacggtgatg gtgggggcag
    22201 gcatgccgat ggctcctgcc tgggtgtcat ctgcgtagaa ggcagcccac cccgggctgc
    22261 cggccaacgt gatgacctgc gtgttcagcg ttctgctgcc gatggcgacg gtgatcctgg
    22321 acgccttccc cgggccgcgg tagatgccgg tgtagagagt gccggaggcg cccccggacg
    22381 cggtggcgga gatcttcccg ctgggtacct ctgccgcgtt cagaacggac tgcttggcgg
    22441 tgccggaaga cttcggggtc accaggaaca ggccctgacc tgtaagccac agcatgttgt
    22501 tccggcccag cgcgaccttc tcaccgggcc ccaccacctg cacttgcgcc gatgctgctg
    22561 ccgaggcggc tgggaccgtg ggtgtgcggg agccgaacga gccgagtgag agggcagcca
    22621 cggcggaggc ggggatgagc acggctgcgg ccagtgccgt agagagtgtt gcctggcggc
    22681 gtcggcgcat tctccgtccc aggcgaacca ccgtctccac gggggccggt tccaccagca
    22741 ggccggcgac ggcctgctgc agcgctgcgg cgaggtcctc gtcctggttc atcggatcgt
    22801 tcctttctgc tgga
//
