LOCUS       NZ_CP020039            22217 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. 3211 isolate 3 chromosome, complete genome.
ACCESSION   NZ_CP020039
VERSION     NZ_CP020039.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. 3211
  ORGANISM  Streptomyces sp. 3211
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8232231)
  AUTHORS   Heinsch,S.C., Hsu,S., Hansen,L., Kinkel,L. and Smanski,M.J.
  TITLE     Complete genomes of three Streptomyces isolated from disease
            suppressive soils
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8232231)
  AUTHORS   Heinsch,S.C., Hsu,S., Hansen,L., Kinkel,L. and Smanski,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAR-2017) Biotechnology Institute, University of
            Minnesota, 1479 Gortner Ave, Saint Paul, MN 55108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-JAN-2017
            Assembly Method                   :: PacBio v. Jan-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:18:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,254
            CDSs (total)                      :: 8,154
            Genes (coding)                    :: 7,815
            CDSs (with protein)               :: 7,815
            Genes (RNA)                       :: 100
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 340
            CDSs (without protein)            :: 339
            Pseudo Genes (ambiguous residues) :: 0 of 340
            Pseudo Genes (frameshifted)       :: 206 of 340
            Pseudo Genes (incomplete)         :: 257 of 340
            Pseudo Genes (internal stop)      :: 68 of 340
            Pseudo Genes (multiple problems)  :: 153 of 340
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:04:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6468006
            Orig. end                         :: 6490223
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP020039.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Michael Smanski.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22217
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="23"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22217
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22217
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12217](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12217)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            243..2645
                     /gene="pucD"
                     /locus_tag="B4U39_RS29765"
     CDS             243..2645
                     /EC_number="1.17.1.4"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pucD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267276.1"
                     /locus_tag="B4U39_RS29765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="xanthine dehydrogenase subunit D"
                     /protein_id="WP_030390556.1"
                     /transl_table=11
                     /translation="MAQNTRTVPAGTPTNVTQKHNKGGIGESILRPDGTLKVTGEFAYS
                     SDMWHEDMLWGQTLRSTVAHAEIVSIDISEALAMPGVYSVLTYDDLPAEMKNYGLEIQD
                     TPVLANGRVRHHGEPVALVAADHPETARRAAAKIKIDYRELPLVTDEASALAPDAPLIH
                     EGRDDHHIGHVPHPNIVHRQPIIRGNVEEARKRADVIVEGEYTFGMQDQAFLGPESGLA
                     VPSEDGGVELYVATQWLHSDLQQIAPVLGLPPEKVRMTLSGVGGAFGGREDISMQIHAC
                     LLALATNKPVKIVYNRFESFFGHVHRHPAKLYYEHGATKDGKLTHMKCKIVLDGGAYAS
                     ASPAVVGNASSLSVGPYVLEDVDIEAIALYTNNPPCGAMRGFGAVQACFAYEAQMDKLA
                     AKLGMDPVEFRQLNAMEMGTVMPTGQVVDAPAPVAELLRRVKARPMPPERQWESAGENA
                     DVRALPGGLSNTTHGEGVVRGVGYAVGIKNVGFSEGFDDYSTARVRLEVINGEPVAMVH
                     TAMAEVGQGGITVHTQIARTELGVTQVTIHPADTQVGSAGSTSASRQTYMTGGAVKNTC
                     EAVREALLEIGRRKNGSYHPAWATAELLLEGGKVVTDGGEVLADIADILEDEAIDLELE
                     FRHAPTEAFDLRTGQGNGHVQYTFAAHRAVVEVDTELGLVKVVELATAQDVGKALNMLS
                     VVGQIQGGTTQGLGVAIMEEIIVDPKTAKVRNPSFTDYLIPTILDTPTIPVDVLELADP
                     KAPYGLRGMGEAPTLSSTPAVIAAIRQATGLEINKTPIRPEALTGTL"
     gene            2967..4430
                     /locus_tag="B4U39_RS29770"
     CDS             2967..4430
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125408.1"
                     /locus_tag="B4U39_RS29770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NCS2 family permease"
                     /protein_id="WP_030390555.1"
                     /transl_table=11
                     /translation="MTQSSVEPKTAAEEAGDGSQPPAGRSWLDRYFHITHRGSNIGNEV
                     RGGITTFMAMAYILLLNPLLLSGKDVAGTSMAASAIITATAFAAAVTTLLMGFVGKVPL
                     ALAAGLSVSGVLASQVAPQMTWPQAMGMCVVYGVVICLLVVTGLREMIMNAIPLALKHA
                     ITMGIGLFVALIGFVKAGFVGRGPEFGPPVQLGAVGELSGWPVMLFCITLIAIFMLQAR
                     KVPGAILIGIVGGTVLAAILNAIVDIDPKAWKSGPPELSGSAISKPDFSLFGDVSFGGW
                     GDVGYMTVGMIVFTLVLAGFFDAMATIIGVGTEAKLADDKGRMPGLSKALFIDGAGGAI
                     GGISGGSGQTVFVESATGVGEGARTGLASVVTGLFFAACLFFTPITQIVPGEVASAALV
                     VIGAMMMQNARHVDWSDSATSIPVFLTVVIMPYTYSITAGVAAGVISYVAIKIAQGKAR
                     EIGGFMWALTGIFLVFFALNPIEHWLGVG"
     gene            4637..5788
                     /locus_tag="B4U39_RS29775"
     CDS             4637..5788
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037137.1"
                     /locus_tag="B4U39_RS29775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="XdhC/CoxI family protein"
                     /protein_id="WP_053177586.1"
                     /transl_table=11
                     /translation="MLDIAEELNRWVEQGRDFAVATVVAVGGSAPRQPGAALAVDSEGT
                     AIGSVSGGCVEGAVYELCLQALEDGETVQERFGYSDDDAFAVGLTCGGIIDILVTPVRV
                     GSPAREVFAAGLAAAARGEAAAVARIAQGPAELMGRAVFVRTEGAHQGGFGGHPELDRT
                     VAEEARAMLDAGRTGVLEIGADGRLCGEPLQVLVESSVPPPRMIVFGAIDFASALVRIG
                     KFLGYRVTVCDARPVFATKTRFPEADEIVVDWPHRYLETTDVDGRTVLCVLTHDAKFDV
                     PLLELALKLPVAYVGAMGSRRTHEDRNKRLREVGVTELELARLRSPIGLDLGARSPEET
                     ALSIAAEIVANRRGGSGAALTGAHIPIHPDITKTVIDRIGSVA"
     gene            6007..7281
                     /locus_tag="B4U39_RS29780"
     CDS             6007..7281
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891457.1"
                     /locus_tag="B4U39_RS29780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YncE family protein"
                     /protein_id="WP_079408091.1"
                     /transl_table=11
                     /translation="MGTLRTLGLLAAAALLTALTPLPAAVGAGPAPGSGPGSGPGGGLR
                     EVLFVGNNWEGTADVLASTGDLAKVGRIDVVPDKAERLREIYLNPVKLAFFLGIRESAG
                     EGHDQFVDDMYTTPDGSAVVVSRPSFADVVSIDVTSGRINWRFPVSGFRSDHMAVSPDG
                     TRVAVSASTSNTVHVLDITTGRQVGSFGTGDKPHENTFTRDGRFLWNSSIGEVNTALDA
                     PWLDWTKGDRKITVVDAQTFRTVRVIDMRERLDAFGRRDLSDAVRPVSFSPDESKLYFQ
                     VSFFGGFLEYDVPSDRITRVKTLPANPATSPDRTTWVNDSRHHGMSMSPDGSKLCIAGT
                     MDDYATVVDRATLAEGPLVPAAKPYWATIDGDGSSCVISESGADQVTAIDFATGAKRVS
                     VPVGDHPQRIRLGHVPAGWTGPATR"
     gene            complement(7341..7808)
                     /locus_tag="B4U39_RS29785"
     CDS             complement(7341..7808)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718707.1"
                     /locus_tag="B4U39_RS29785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="OsmC family protein"
                     /protein_id="WP_079406508.1"
                     /transl_table=11
                     /translation="MARLHSYATRVTWTGNLGTGTSHYRAYSRAHEVAAGELPAILGSS
                     DPTFRGDASRWNPEQLLLAALSQCHMLSYLHFCTINGVVVTSYVDEATGTMATAGDSGH
                     FTEVVVHPRITVGEESMVAAAIDLHEEAHRACFIANSVNFPVRHEPTVTVG"
     gene            complement(7983..8525)
                     /locus_tag="B4U39_RS29790"
     CDS             complement(7983..8525)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677098.1"
                     /locus_tag="B4U39_RS29790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family protein"
                     /protein_id="WP_079406509.1"
                     /transl_table=11
                     /translation="MIEGERVALRALRAQDAQHHLRWRNDPEVVRWATAGDPCFGPVTR
                     EALTMSFERMLMLPPRESAVFTVETVADRRVIGMVDYRDLDPWAGTATLGITIGEREFW
                     GRGHGSEALRLLVDHLFGSFPLTRLQLDTWSGNERAVRAFTRLGFREEGRRRAAVLLAG
                     ERYDEVLFGMLREEWRP"
     gene            8714..9958
                     /locus_tag="B4U39_RS29795"
     CDS             8714..9958
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743398.1"
                     /locus_tag="B4U39_RS29795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_079406510.1"
                     /transl_table=11
                     /translation="MVDIREVPESDIDRALELAYLVFHDRPEKEVREKHHALLASCDRI
                     GAYDGAALVGFMAAHDFRLSVPGADLPCPGLTFVCVAPTHRRRGVLTGLMARMLRRTAA
                     AAGPIAALWASEAAIYGRFGYGSATTGATIEIDSTRPLALRIAPDRRPLRLLDPEEALA
                     VIGPFHEAARAGRAGRPSRSAQRWREEWLAEQDEEDEELSPPRIIVLGDPGEPIAGYVL
                     YRTKAEDDAAAVRVPGRVRVDELEADTPAVAAALWECVASLDLTGKVSAWGRPVDDPLL
                     HFAADRDQVRVTAQFPALWVRLVDVRAALTARSWAAPVEVVLEVQDVRLPANAGRFRLK
                     AGPHGATYEHDHADSGATADLALDVRELAACYLGGTRVEELVAAGLVQEHTPGAAAALD
                     AALRTPVLPHTSDEF"
     gene            complement(10001..12217)
                     /locus_tag="B4U39_RS29800"
     CDS             complement(10001..12217)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743400.1"
                     /locus_tag="B4U39_RS29800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Geosmin synthase"
                     /protein_id="WP_079406511.1"
                     /sec_met_domain="T1TS (E-value: 2.4e-76, bitscore: 256.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFQLPDFYVPYPARLNPHLEDARTHTKQWARDFGMLEGSGVW
                     EESDLDSHDYALLCSYTHPDCDRDALALVTDWYVWVFFFDDHFLEMYKRSQDRNGAKEY
                     LDRLAAFMPMDLSGGFPEATNPVEAGLADLWARTVPAMSADWRERFSLSTKNLLNESMW
                     ELANINIGRVANPLEYIEMRRKVGGAPWSAGLIEYVSAEVPARVAHSRALGVLRDSFSD
                     AVHIRNDIFSYQREVADEGELSNAILVLETFLGCTTQEAAEASNDLLTSRLQQFEQTAL
                     VELPQLFADHALDPAEIAAVLAYTKGLQDWQSGGHEWHMVSSRYMNKEARPTAPATLPF
                     LPSGLGTTALDLRSVFTKRSMELRHRSFTHVPFERTGPSVIPEIYMPHRLSLSPHLAHA
                     REESVAWARRMGLLDPQPGDPGSAIWTEERLRGFDFAVCSAGIDPDATPEQLVLNASWL
                     TWGTYGDDYYPVVFARGRNLPAAKATTARLISMIPVDHAEQPEPVTAMERSLGDLWVRT
                     SAGMSVEQRTEFRATLVSMLESWLWEVDNQIQNRIPDPVDYAEMRRHTFGSHLTMYLCR
                     LGHRGRGIPEEIYASGTIRSLENAVADAACLINDIYSYQKEVEVEGEVHNYILVAQNFF
                     DIGYPQALHICHELMTRRTEEFEHIVATQLPVLYDDWKLGAGAREALDAYVGELQDWHA
                     GILNWHQKIRRYRPQDLHPQPDLLATGILGNGFGMAAARISLPA"
     gene            12511..12732
                     /locus_tag="B4U39_RS29805"
     CDS             12511..12732
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008411999.1"
                     /locus_tag="B4U39_RS29805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_030390548.1"
                     /transl_table=11
                     /translation="MAIDLDKVLDKAWADKPLAEVLAAPVAALKGVSDEDGKLLHEAFG
                     VKTVADFGQLKYVRWAQALVALNQTVKA"
     gene            complement(12840..16457)
                     /gene="cobN"
                     /locus_tag="B4U39_RS29810"
     CDS             complement(12840..16457)
                     /EC_number="6.6.1.2"
                     /GO_function="GO:0051116 - cobaltochelatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobN"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1263: cobaltochelatase subunit CobN"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743402.1"
                     /locus_tag="B4U39_RS29810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cobaltochelatase subunit CobN"
                     /protein_id="WP_079406512.1"
                     /transl_table=11
                     /translation="MILLLSTSDTDLLSARAANTADGPVPYRFANPSRLPLDDLPGLLD
                     GADLVVVRLLGGLRAWQDGLDLLLAPGQTRPVVVLTGEQAPDAQLMEASTVPIGIAAEA
                     HGYLAHGGPANLEQLARFLSDTVLLTGHGFEPPAASPTWGPLERTPGTIAGPRIAVLYY
                     RAHQMSGNTSFVHALCDAIEAHDAQALPLYVSSLRTPEPELIAALESADAVVTTVLAAG
                     GTKPATASAGGDDESWDAGALAGLGVPILQALCLTGSRAAWEENDEGLSPLDAATQVAV
                     PEFDGRLITVPFSFKEIDEDGLPAYVADPERAARVAGIAVRHARLRHIDRRDKKVALVL
                     SAYPTKHSRIGNAVGLDTPASAVELLRTLIAGGYDFGPTEDIPGLVSGDGDELIRALIE
                     AGGHDQDWLTEEQLARNPVRIPAADYKRWFAELPAELRDSVTEHWGEAPGNMFVDRSAN
                     PEGDIVLAALRRGNLLILIQPPRGFGENPIAIYHDPDLPPSHHYLAAYRWIQARAQDGG
                     FGADAMIHLGKHGNLEWLPGKNAGLSAACAPDAALGDLPLIYPFLVNDPGEGTQAKRRV
                     HATLVDHLVPPMARAESYGDIARLEQHLDEYAQISAMDPAKLPAIRAQIWTLIQAAKLD
                     HDLGLEERPDDDGFDDFLLHVDGWLCEVKDAQIRDGLHVLGGAPTGEARVNLVLAILRA
                     RQIWGGTTALPGLREALGLDESKATRTSADAVEAQARALVQAMEDANWSLDAVPTVAAD
                     HAADVAAVLSFAAREVVPRLAGTTDEIAHVIAALDGRFIPAGPSGSPLRGLVNVLPTGR
                     NFYSVDPKAVPSRLAWETGQALAESLLTRYRTDNGEWPASVGLSLWGTSAMRTSGDDVA
                     EALSLLGIRPVWDEASRRVTGLEPIPLAELGRPRIDVTLRISGFFRDAFPHVIGLLDDA
                     VRLAASLEEPAADNFVRAHAQADLAEHGDERRATTRIFGSRPGTYGAGILQLIDSRDWR
                     TDADLAEVYTVWGGYAYGRGLEGRPARDEMETAYKRITVAAKNTDTREHDIADSDDYFQ
                     YHGGMVATVRALRGTAPEAYIGDSTRPETVKTRTLVEETSRVFRARVVNPKWIEAMRRH
                     GYKGAFELAATVDYLFGYDATTGVVADWMYDKLTETYVLDPTNRAFLEEANPWALHGIA
                     ERLLEAESRGMWEKPDPQILESLRQVYLDTEGNLEGESE"
     regulatory      complement(16513..16596)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            17083..18375
                     /gene="cobG"
                     /locus_tag="B4U39_RS29815"
     CDS             17083..18375
                     /EC_number="1.14.13.83"
                     /GO_function="GO:0016709 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, NAD(P)H as one donor, and incorporation
                     of one atom of oxygen [Evidence IEA]"
                     /GO_process="GO:0019250 - aerobic cobalamin biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="cobG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004938317.1"
                     /locus_tag="B4U39_RS29815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="precorrin-3B synthase"
                     /protein_id="WP_237296854.1"
                     /transl_table=11
                     /translation="MPQPPSAASRDEPVIRQRGDACPGALRLHAADDGFLARVRLPGGL
                     LTGPQAAALALAADRFGDGHLELTSRGNVQLRGLADGCGGALAELLDGAGLLPAPSHER
                     VRNIVATPLSGLEGPDRPDALAWAMEFDRLLCASPWAAALSGRFLFAFDDGRGDVASLG
                     PDVTVLGRPAGRALVRLGRAADAVELAGPDAPRAALSAARYFLDAAAEAGTQAWRVSEL
                     PDEHALGTVEFVRRLEAVGIAAAAVGAVDWPYAPAPRPPGAGTRARATLCVLPPLGRVD
                     SVQWRVLAQVAQEGGGELRVTPWRSVILPSVHGDAPARIEDAGLVVAPDSPWETVTACT
                     GRPGCAKSLADVRADARAVVDRARGPLPVHWSGCERRCGHPRGTAWVDLVATGTGYRIT
                     APGRPVRDDVRPPELAAALADARTDPDVVKK"
     gene            18372..19019
                     /locus_tag="B4U39_RS29820"
     CDS             18372..19019
                     /EC_number="5.4.99.61"
                     /GO_function="GO:0016993 - precorrin-8X methylmutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267284.1"
                     /locus_tag="B4U39_RS29820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="precorrin-8X methylmutase"
                     /protein_id="WP_030389756.1"
                     /transl_table=11
                     /translation="MSEYTVFEYEKDGAAIYRQSFATIRAEADLSGLPDTVAQVAVRMI
                     HACGMTDLPQDLGYTPEVVLRARAALEAGAPILCDVQMVASGVTRKRLPADNDVICTLS
                     DPAVPELAARMGTTRSAAALEVWRDRGLLEGSVIAVGNAPTALFRLLEMIEEGAPRPAA
                     VIGVPVGFIGAAESKDALAAHPSGLDHLIVRGRRGGSAMAAAAVNAIASVAE"
     gene            19016..20515
                     /locus_tag="B4U39_RS29825"
     CDS             19016..20515
                     /EC_number="2.1.1.130"
                     /GO_function="GO:0030788 - precorrin-2
                     C20-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267285.1"
                     /locus_tag="B4U39_RS29825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="precorrin-2 C(20)-methyltransferase"
                     /protein_id="WP_030389757.1"
                     /sec_met_domain="TP_methylase (E-value: 2.9e-50, bitscore:
                     169.9, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAEAKGRLYGVGLGPGDPSLMTLRAVEVIAEADVVAYHSARHG
                     RSIARSIAAKHLRADHVEEPLVYPVTTETTDHPGGYQGAMEEFYEAAAARLAAHLDAGR
                     TVAVLAEGDPLFYSSYMHMHKRLADRYETEVIPGVTSVSAAAARLGTPLVEGEEVLTIL
                     PGTLSEEELTARLAATDSAVVMKLGRTFPAVRGAMENSGRLAEARYVERATMAGERTGR
                     LADTDPESVPYFAVAVVPSRIGNPGSVPSGPGEVVVVGTGPAGPLWLTPQTRRALADAE
                     VLVGYTTYLDRVPVRPGQIRHGSDNKVESERAEFALDLARRGQRVAVVSGGDPGVFAMA
                     TAVLEVAGQAEYKDVPVRVLPGVTAANAAAAAAGAPLGHDYATVSLSDRLKPWEVIAER
                     LRAAAAADLVLALYNPGSRSRTWQVAQARELLLELRSPETPVVVARDVGGPEQTVRIVT
                     LAELEPSEVDMRTILLIGSSQTQVTERADGSRITWTPRRYP"
     gene            20701..21903
                     /locus_tag="B4U39_RS29830"
     CDS             20701..21903
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240754.1"
                     /locus_tag="B4U39_RS29830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_237296855.1"
                     /transl_table=11
                     /translation="MLDQPRRPGSGAAAAVVAFAFWITMAGTTVPTTLYPLYGEAMGFS
                     PITVTAIFAVYAVGVVVGLLLLGRLSDQIGRRPVLLAATFLSVCGALVFLVADSVPALC
                     VARVISGFSAALITGAATASLTELLPGDSRIKPATVALFANMGGLASGTLAAGVLADLA
                     PEPLRTPWIVTLVLAALAVIGVASTRETSAHRSGFTFHARLLHVPAEIRSDFLRSATAA
                     GTGFAVLGVLTAVTGLFMGQVLHESGHTLAGLVVFTAFACTALGQLLVRAVRPGAVLVV
                     ACLGLMLAAALMAAAMAAQAFAPLLIGAAVNGLATGMAVSHGIRDITTRSAPRHRGASV
                     STFFAILYSMLAVPAIGVGVLIRATSLRPAGEVFSAAVAVLALVVLLSLVLRRKPAGAA
                     A"
ORIGIN
        1 ggcgagggcg tggagctctc caacatccag caggcgttca tcgacgccgg cgccgtgcag
       61 tgcggtttct gcaccccggg tctgctcatc caggcggacg cgctgctgga ggagaactcc
      121 tccccgtccg accaggacat ccgtgaggcc ctgtccggca acctctgccg ctgcacgggc
      181 tacgagaaga tcctcgacgc ggtccgcctc gcggccgccc gtcagtcaga ggcggtctga
      241 ccatggctca gaacacccgc accgtgcccg ccggtacgcc gacgaacgtc acccagaagc
      301 acaacaaggg cggcatcggc gagtccatcc tccgtccgga cggcaccctc aaggtcaccg
      361 gcgagttcgc gtactcctcg gacatgtggc acgaggacat gctgtggggc cagacgctgc
      421 gcagcaccgt cgcccacgcc gagatcgtct ccatcgacat ctccgaggcg ctcgccatgc
      481 ccggcgtgta ctcggtgctg acgtacgacg acctgccggc cgagatgaag aactacggcc
      541 tggagatcca ggacaccccg gtcctcgcca acggccgggt acggcaccac ggtgagccgg
      601 tcgccctcgt ggccgccgac cacccggaga ccgcccgccg cgcggccgcc aagatcaaga
      661 tcgactaccg cgagctgccg ctcgtcaccg acgaggcctc cgccctcgcc cccgacgcgc
      721 cgctgatcca cgagggccgc gacgaccacc acatcggtca cgtcccgcac ccgaacatcg
      781 tgcaccgcca gccgatcatc cgcggcaacg tggaggaggc ccgcaagcgc gccgacgtca
      841 tcgtcgaggg cgagtacacc ttcggcatgc aggaccaggc cttcctcggc ccggagtccg
      901 gcctggccgt accgtccgag gacggcggtg tcgagctgta cgtcgccacc cagtggctgc
      961 actcggacct ccagcagatc gccccggtcc tgggcctgcc cccggagaag gtccgtatga
     1021 ccctctcggg cgtcggcggt gccttcggcg gccgcgagga catctcgatg cagatccacg
     1081 cctgcctcct ggccctggcc acgaacaagc cggtcaagat cgtctacaac cggttcgagt
     1141 ccttcttcgg ccacgtgcac cgccacccgg cgaagctcta ctacgagcac ggcgccacca
     1201 aggacggcaa gctcacgcac atgaagtgca agatcgtcct ggacggcggc gcgtacgcgt
     1261 ccgcctcccc ggcggtcgtg ggcaacgcct cctccctctc ggtgggtccc tacgtcctgg
     1321 aggacgtgga catcgaggcg atcgcgctct acacgaacaa cccgccctgc ggtgcgatgc
     1381 gcggcttcgg cgccgtccag gcctgcttcg cctacgaggc ccagatggac aagctcgcgg
     1441 cgaagctggg catggacccg gtggagttcc gccagctcaa cgccatggag atgggcacgg
     1501 tcatgccgac cggccaggtc gtggacgccc cggcgcccgt cgccgagctg ctgcgccgcg
     1561 tcaaggcccg cccgatgccg ccggagcgcc agtgggagag cgccggcgag aacgcggacg
     1621 tccgtgcgct gcccggcggt ctgtcgaaca ccacccacgg cgagggcgtc gtccgcggcg
     1681 tcggctacgc ggtcggcatc aagaacgtcg gcttctccga gggcttcgac gactactcga
     1741 ccgcccgcgt gcggctcgag gtcatcaacg gcgagcccgt cgcgatggtc cacacggcca
     1801 tggcggaggt cggccagggc ggcatcaccg tccacacgca gatcgcccgt acggagctgg
     1861 gtgtcaccca ggtgaccatc catccggccg acacgcaggt cggctccgcc ggttccacgt
     1921 ccgcctcgcg gcagacgtac atgaccggtg gcgccgtgaa gaacacctgt gaggcggtcc
     1981 gcgaggccct gctggagatc ggccgccgca agaacggctc gtaccacccg gcgtgggcga
     2041 cggccgagct gctgctcgaa ggcggaaagg tcgtcaccga cggcggcgag gtcctcgcgg
     2101 acatcgccga catcctggag gacgaggcca tcgacctcga gctcgagttc cgtcacgcgc
     2161 ccaccgaggc cttcgacctg cggaccggcc agggcaacgg ccacgtccag tacaccttcg
     2221 ccgcgcaccg cgcggtcgtc gaggtggaca ccgagctcgg cctggtcaag gtcgtcgagc
     2281 tggcgaccgc gcaggacgtc ggcaaggccc tcaacatgct ttccgtggtc ggccagatcc
     2341 agggtggtac cacccagggt ctcggcgtcg cgatcatgga ggagatcatc gtggacccga
     2401 agaccgcgaa ggtgcgcaac ccctccttca cggactacct gatcccgacc atcctcgaca
     2461 ccccgaccat tccggtcgac gtcctggagc tcgccgaccc gaaggccccc tacggcctgc
     2521 gcggtatggg cgaggccccg accctctcgt ccaccccggc cgtcatcgcg gcgatccggc
     2581 aggcgacggg tctggagatc aacaagacgc cgatccgtcc ggaagccctc accgggaccc
     2641 tctaggacgg cgtggtccgg gggccgagag gcccccggac ctcctcagac tctccgggcg
     2701 gtgcgcatgg gaacgtcaca cttcacgtcg caccgtccgg aggaccaacg aagcaccgca
     2761 ccgctcgcgg tcccttcacc cggcagtacc cctgcaagaa cccccgtagt accagcggtc
     2821 acccccgcac tacccgcagt acacgcagtg cacattcgcg tcgcctcggg ccgtcacccc
     2881 gggtcgtgca gccaaacgca gcatcccaaa tcccgcatct ccaatctcca agcgggtgcc
     2941 cctttgaacc ttgggagtta ggcaccatga cccaatcgtc agtagagccc aagaccgcag
     3001 cggaagaggc cggcgacggc tctcagccac ccgccggcag gtcctggctc gaccggtact
     3061 ttcacataac gcacagaggc tccaacatcg gcaatgaggt tcgtggcggt atcacgacct
     3121 tcatggcgat ggcgtacatc cttctgctca accccctgct cctctcgggc aaggacgtcg
     3181 ccggtacgtc gatggccgcc tcggcgatca tcaccgccac cgcgttcgcc gcggccgtca
     3241 ccacgctcct catgggcttc gtcggcaagg tgccgctcgc ccttgccgcc ggcctctccg
     3301 tgtccggcgt gctggcctcg caggtggccc cccagatgac ctggccgcag gccatgggca
     3361 tgtgtgtggt ctacggcgtc gtgatctgtc tcctggtcgt caccggcctc cgcgagatga
     3421 tcatgaacgc gatccccctc gcgctcaagc acgcgatcac catgggcatc ggcctcttcg
     3481 tcgccctgat cggcttcgtc aaggccggct tcgtgggcag gggtccggag ttcggtcccc
     3541 ccgtccagct cggtgcggtc ggtgagctgt ccggctggcc cgtcatgctc ttctgcatca
     3601 ccctgatcgc catcttcatg ctccaggccc gcaaggtgcc cggcgccatc ctgatcggca
     3661 tcgtcggcgg caccgtcctg gccgcgatcc tcaacgccat cgtcgacatc gacccgaagg
     3721 cctggaagag cggcccgccg gagctcagcg gctccgcgat ctcgaagccg gacttctcgc
     3781 tcttcggcga cgtctccttc ggcggctggg gcgacgtcgg ctacatgacg gtcggcatga
     3841 tcgtcttcac cctggtgctc gccggcttct tcgacgccat ggccaccatc atcggtgtcg
     3901 gcaccgaggc caagctggcc gacgacaagg gccgcatgcc gggcctgtcc aaggcgctct
     3961 tcatcgacgg cgccggtggc gccatcggtg gcatctcggg cggctccggt cagaccgtct
     4021 tcgtcgagtc cgcgaccggc gtcggcgagg gtgcccgcac gggtctcgcc tccgtcgtca
     4081 ccggcctgtt cttcgccgcc tgcctcttct tcaccccgat cacgcagatc gtcccgggtg
     4141 aggtcgcctc cgcggcgctg gtcgtcatcg gcgcgatgat gatgcagaac gcccgccacg
     4201 tggactggtc cgacagcgcg acctcgatcc cggtcttcct gaccgtcgtg atcatgccgt
     4261 acacgtactc gatcacggcc ggcgtcgccg ccggtgtcat ctcgtacgtg gccatcaaga
     4321 tcgctcaggg caaggcccgg gagatcggcg gcttcatgtg ggcgctgacc gggatcttcc
     4381 tggtgttctt cgccctgaac ccgatcgagc actggctcgg ggtcggctga cccgcaccga
     4441 tcaggtcggt ccaccgatga gaccggcctg atcgacctgc tcgatctgct cgacctgctc
     4501 cgcccggtcg actgctcccg tggtcgacct gctccgcccg atcgaccggg tcgacccgat
     4561 ccggtcgacc cggtcgtcga gaaccgaacg ctccccgtat ccgatactgg aaccgaacct
     4621 caccgaggag gcccccatgc tggacatcgc cgaagagctg aaccggtggg tcgagcaggg
     4681 acgtgacttc gccgtcgcca ccgtcgtggc ggtcggcggg agcgcgcccc ggcagcccgg
     4741 tgccgccctc gccgtcgaca gcgagggcac ggccatcggc tcggtctccg gcggatgcgt
     4801 ggagggcgcg gtctacgagc tgtgcctcca ggcgctggag gacggcgaaa ccgtccagga
     4861 gcgcttcggg tacagcgacg acgatgcctt cgccgtgggc ctgacctgcg gcggaatcat
     4921 cgacatcctg gtcaccccgg tccgcgtggg ctcacccgcc cgggaggtgt tcgcggccgg
     4981 cctggccgcc gcggcccgcg gcgaggccgc ggcggtggcc cggatagcgc agggaccggc
     5041 cgagctcatg ggccgcgccg tgttcgtccg taccgaaggc gcccaccagg gcggattcgg
     5101 cggacacccc gagctggacc gcaccgtggc cgaggaggcc cgcgccatgc tcgacgccgg
     5161 ccggaccggc gtgctggaga tcggcgccga cggccggctc tgcggtgagc cgctccaggt
     5221 cttggtcgag tccagcgtcc cgcccccgcg gatgatcgtc ttcggtgcca tcgacttcgc
     5281 ctccgccctc gtgcggatcg gcaagttcct cggctaccgc gtgacggtgt gcgacgcccg
     5341 gcccgtcttc gcgacgaaga cccgcttccc cgaggcggac gagatcgtcg tcgactggcc
     5401 ccaccgctac ctggagacca ccgacgtgga cggccggacc gtcctgtgcg tgctcaccca
     5461 cgacgccaag ttcgacgtcc cgctcctcga actggcgctc aagctgcccg tcgcctacgt
     5521 cggcgccatg ggctcgcgcc gcacccacga ggaccgcaac aagcggctgc gcgaggtcgg
     5581 cgtgaccgag ctcgaactgg cccggctgcg ctccccgatc ggcctggacc tcggcgcccg
     5641 ctccccggag gagaccgcgc tgtccatcgc cgccgagatc gtcgcgaacc gccgcggcgg
     5701 cagtggcgcg gccctgaccg gcgcgcacat cccgatccac ccggacatca cgaagacggt
     5761 gatcgaccgg atcggatccg tggcttgact gcctgaccgg ccgcccggtc accgaaggtg
     5821 aggaaagggc gcaacccgtg ggggttgcgc ccttttgacg tcccccctat cttaccggcc
     5881 ggtaagagga ggcaccctct ccatcccttc ccccgtagcg gagttgagcg gatgttacga
     5941 accgtgggca cccggcgaac cgcgcgtacc ccgcgcaccc tgcgacccgc gcgcaccctg
     6001 cggcccctgg gcaccctgcg gaccctgggc ctgctggccg cggccgccct cctcaccgcc
     6061 ttgacgccgc tcccggcggc ggtcggggcg ggccctgctc cgggctccgg tcccggcagc
     6121 ggccccggcg gcgggctgcg cgaggtgctc ttcgtgggga acaactggga gggaaccgcc
     6181 gacgtgctcg cctccaccgg cgacctcgcc aaggtcggcc ggatcgacgt ggtccccgac
     6241 aaggcggaac ggctgcgcga gatctacctc aaccccgtga agctcgcctt cttccttggc
     6301 atccgggaga gcgccggcga ggggcacgac cagttcgtcg acgacatgta caccaccccc
     6361 gacggctccg ccgtggtcgt ctcccgcccc agcttcgccg acgtcgtgtc catcgacgtg
     6421 acctccggcc ggatcaactg gcgtttcccg gtgtccggtt tccggtccga ccacatggcc
     6481 gtctccccgg acgggacccg cgtcgccgtg tcggcctcca cctccaacac cgtgcacgtc
     6541 ctggacatca ccaccgggcg ccaggtcggc tccttcggca ccggcgacaa gccgcacgag
     6601 aacaccttca cccgcgacgg ccgcttcctg tggaacagct ccatcggcga ggtcaacacg
     6661 gccctggacg cgccctggct ggactggacg aagggcgacc gcaagatcac cgtggtcgac
     6721 gcgcagacct tccgcacggt ccgggtgatc gacatgcgcg agcggctgga cgccttcggc
     6781 cgccgcgacc tgtccgacgc cgtccgcccg gtgtccttca gccccgacga gtcgaagctc
     6841 tacttccagg tgtccttctt cggcggcttc ctggagtacg acgtgccctc cgaccggatc
     6901 acccgcgtga agaccctccc cgcgaacccc gccaccagcc ccgaccggac cacctgggtc
     6961 aacgactccc gccaccacgg catgtccatg agccccgacg ggtcgaagct ctgcatcgcg
     7021 ggcaccatgg acgactacgc gaccgtcgtg gaccgggcca ccctcgccga aggcccgctc
     7081 gtgcccgccg ccaagccgta ctgggccacg atcgacggcg acggcagcag ctgcgtcatc
     7141 tccgagagcg gcgccgacca ggtcacggcc atcgacttcg ccaccggcgc caagcgggtc
     7201 tccgtccccg tcggcgacca tccccagcgc atccggctcg gccacgtccc ggccggctgg
     7261 accggccccg ccacccgtta gggagcgggc gtcctggtcc cgttgcggga ccacggcgcg
     7321 accgggccgg cccggtcggc tcagcccacc gtcacggtcg gctcgtgccg gacggggaag
     7381 ttgaccgagt tggcgatgaa gcaggcccga tgggcctcct cgtgcaggtc gatcgccgcg
     7441 gccaccatcg actcctcgcc gacggtgatc cgggggtgca ccacgacctc cgtgaagtgc
     7501 ccgctgtccc cggccgtggc catcgtcccg gtcgcctcgt cgacgtacga ggtgaccacc
     7561 acgccgttga tcgtgcagaa gtgcaggtag gagagcatgt ggcactggga cagcgcggcg
     7621 agcagcagtt gctcggggtt ccagcgggag gcatcgccgc ggaacgtggg gtccgagctg
     7681 ccgaggatcg ccggcagctc tccggcggcc acctcgtgcg cccgggagta ggcgcggtag
     7741 tggctggtgc cggtgccgag gtttccggtc caggtgacgc gggtggcgta ggagtgcagt
     7801 cgggccatgg cggctactcc gtctctcggg tgcggggccg ggcgacacgc gtgcccgggg
     7861 tgtggcggcg acgtcgggcg gtgccgggcg ccgacctgga tggtacggcc gacgcgacgg
     7921 ccgcgtcggc tgcgtcggcc gcttcctcca cgaggtaccc ggcgggcgca ccgccggccg
     7981 ggtcagggcc gccactcctc ccggagcatc ccgaacagca cctcgtcgta ccgctcgccc
     8041 gccagcagca cggccgcccg ccgccggccc tcctcccgga agccgagccg ggtgaacgcc
     8101 cggaccgccc gctcgttccc gctccaggtg tcgagctgga gccgggtgag ggggaagctg
     8161 ccgaagaggt ggtcgaccag cagccgcaac gcttcggagc cgtgtccccg gccccagaac
     8221 tcccgctcgc cgatggtgat cccgagcgtg gccgttccgg cccaggggtc caggtcgcgg
     8281 tagtcgacca tgccgatcac ccggcggtcc gccacggtct ccaccgtgaa caccgccgac
     8341 tcccggggcg ggagcatcag catccgctcg aaggacatcg tcagcgcctc ccgggtgacc
     8401 gggccgaagc acgggtcccc ggcggtcgcc caacggacca cctcggggtc gttgcgccag
     8461 cgcaggtggt gctgcgcgtc ctgcgcgcgc agtgcgcgca gcgcgacgcg ctctccctcg
     8521 atcaagccct gatcctctcc ccgtccctgt ggcatccgag cgcacaccgt acccacaggt
     8581 gatcatggcg gcgacgggtt ttcggagccg ccgaggtacc ccgccccggc ggccggccac
     8641 cggagcagcc gaaagccgca acctcgacct ttatggggtg accagtcctc catgaccgat
     8701 tagtctcgcg atcatggtgg acatccgcga ggtacccgag tccgacatcg accgtgctct
     8761 ggagctcgcc tacctggtct tccacgaccg gcccgagaag gaggtccggg agaaacacca
     8821 cgcgctgctc gcgagttgcg accggatcgg cgcctacgac ggcgccgccc tggtcggttt
     8881 catggccgcg cacgacttcc ggctctcggt gcccggggcg gacctgccct gccccgggct
     8941 caccttcgtc tgcgtcgccc ccacccaccg ccggcgcggc gtactcaccg ggctgatggc
     9001 gcggatgctg cggcggacgg ccgccgcggc cggtccgatc gccgccctct gggcctccga
     9061 agccgccatc tacggccgct tcggctacgg cagcgccacc accggcgcca ccatcgaaat
     9121 cgactccacc cgcccgctgg ccctgcgcat cgcaccggac cggcggccgc tgcggctcct
     9181 cgaccccgag gaggccctcg ccgtgatcgg ccccttccac gaggccgccc gcgccgggcg
     9241 ggccggccgg cccagccgca gcgcgcagcg ctggcgcgag gagtggctgg ccgaacagga
     9301 cgaggaggac gaggagctga gcccgccgcg gatcatcgtc ctcggggacc ccggcgagcc
     9361 gatcgccgga tacgtgctct accgcaccaa ggcggaggac gacgccgcgg ccgtccgcgt
     9421 gccgggccgg gtccgggtcg acgagctgga ggccgacacc ccggcggtgg ccgccgcgct
     9481 gtgggagtgc gtggcctccc tcgacctcac cggcaaggtc tcggcgtggg gccgcccggt
     9541 cgacgacccg ctgctgcact tcgccgcgga ccgggaccag gtgcgggtca ccgcccagtt
     9601 cccggcgctc tgggtgcgcc tggtcgacgt acgggccgcc ctgacggcgc ggtcctgggc
     9661 cgcgccggtg gaggtggtgc tggaggtgca ggacgtacgg ctgcccgcca acgccgggcg
     9721 gttccggctc aaggcggggc cgcacggggc gacgtacgag cacgatcacg cggactccgg
     9781 cgccaccgcc gacctggccc tggacgtccg tgaactggcc gcctgctacc tcggcgggac
     9841 ccgggtcgag gagctcgtcg cggccggtct ggtacaggag cacacgcccg gtgcggcggc
     9901 ggcgctggac gcggccctgc gtacgccggt actgccgcac acgagcgacg agttctgacc
     9961 cgtacggcgg gggcggggcc cccgccgcag ggcgccggga tcaggcgggc agggagatcc
    10021 gggcggccgc catgccgaag ccgttgccca ggatcccggt ggccagcagg tcgggctgcg
    10081 gatgcaggtc ctgcgggcgg taacggcgga tcttctggtg ccagttgagg atgccggcgt
    10141 gccagtcctg caactcgccc acgtacgcgt ccagcgcctc ccgggccccg gcgccgagct
    10201 tccagtcgtc gtagagcacc ggcagctgcg tggccacgat gtgctcgaac tcctcggtcc
    10261 gccgggtcat cagctcatgg cagatgtgca gggcctgcgg gtagccgatg tcgaagaagt
    10321 tctgtgcgac caggatgtag ttgtggacct cgccctcgac ctccacctcc ttctggtagg
    10381 agtagatgtc attgatcagg caggcggcgt ccgcgaccgc gttctccagt gaacggatgg
    10441 tcccggaggc gtagatctcc tcggggatgc cccggccccg gtgccccagg cggcacaggt
    10501 acatcgtgag atggctgccg aaggtgtggc ggcgcatctc cgcgtagtcc accgggtccg
    10561 ggatgcggtt ctggatctgg ttgtccacct cccacagcca gctctccagc atgctcacca
    10621 gggtcgcccg gaattccgtg cgctgctcga cggacatgcc ggcgctggtg cgcacccaca
    10681 ggtcgccgag cgagcgctcc atcgcggtca ccggctcggg ctgttcggcg tggtcgaccg
    10741 ggatcatgga gatcaggcgg gcggtggtcg ccttggccgc cggaaggttc ctgccccggg
    10801 cgaagaccac cgggtagtag tcgtccccgt acgtgcccca ggtcagccag gaggcgttga
    10861 gcaccagctg ctccggtgtg gcgtcggggt cgatcccggc cgagcagacg gcgaagtcga
    10921 agccgcgcag ccgctcctcg gtccagatgg ccgagccggg gtcgccgggc tgcgggtcca
    10981 gcagtcccat ccgccgggcc caggccacgg attcctcgcg cgcgtgcgcc aggtgcgggc
    11041 tgaggctgag ccggtgcggc atgtagatct cggggatgac ggaggggccg gtgcgctcga
    11101 agggcacgtg ggtgaaggag cggtggcgca gctccatcga gcgcttcgtg aacacggacc
    11161 gcaggtcgag cgcggtggtg ccgagtccgg acggcaggaa gggcagggtg gcgggggcgg
    11221 tgggccgggc ctccttgttc atgtagcggc tggagaccat gtgccactcg tggccgccgg
    11281 actgccagtc ctgcaggccc ttggtgtagg cgagcacggc cgcgatctcc gccgggtcca
    11341 gcgcgtggtc ggcgaagagc tgggggagct cgacgagcgc ggtctgctcg aactgctgga
    11401 ggcgggaggt gagcaggtcg ttggaggcct cggcggcctc ctgggtggtg cagccgagga
    11461 aggtctccaa caccaggatg gcattggaga gttcaccctc gtcggcgacc tcgcgctggt
    11521 aggagaagat gtcgttcctg atgtgcacgg cgtcggagaa ggagtcgcgc agcacgccga
    11581 gtgcgcgcga gtgcgcgacg cgcgcgggca cctcggcgga cacgtactcg atcaggccgg
    11641 ccgaccaggg ggcgccgccc accttgcggc gcatctcgat gtattcgagc gggttcgcga
    11701 cgcgcccgat gttgatgttg gcgagctccc acatggactc gttgaggagg ttcttcgtcg
    11761 acaaggagaa ccgttcccgc cagtcggcgg acatcgcggg cacggtgcgc gcccacaggt
    11821 ccgcgagtcc cgcctccacc gggttggtgg cctcggggaa cccgccggac aggtccatcg
    11881 gcatgaacgc ggcgagccgg tcgaggtact ccttggcgcc gttgcggtcc tgcgagcgct
    11941 tgtacatctc caggaagtgg tcgtcgaaga agaacaccca cacgtaccag tccgtgacca
    12001 gcgccagcgc gtcgcggtcg cagtcggggt gggtgtacga gcagagcagt gcgtagtcgt
    12061 gcgagtcgag gtcgctctcc tcccagacgc cggaaccctc cagcatcccg aagtcgcggg
    12121 cccactgctt ggtgtgggtc cgtgcgtcct ccaggtgggg gttcagtcgt gccggatagg
    12181 gcacatagaa atccggcagt tgaaacggct gcgtcacggc gggctcggcc tttcgtccat
    12241 gggtacgggg agcccggtcg ccccggtccc cccgcacgag atcagcagtg ccctacccct
    12301 ggtgcgcatg ggacaagggt gaattcactt catcaggtga cgaaccaccc gttccccgac
    12361 acggggccct gctgggggct agggggtgtc ttgggggcag cccccgcacg gcggatcggc
    12421 aacgggcccg gggtgtcgga gcgtggggtg attgtcggat tgggttaggt ttgccccgat
    12481 attcggttcg ggattccgag agggacgttc atggcgatcg atctggacaa ggtgctcgac
    12541 aaggcgtggg ccgacaagcc gctcgccgag gtgcttgcgg ctcctgttgc cgcgctcaag
    12601 ggtgtcagtg acgaggacgg caagctgctg cacgaggcgt tcggggtcaa gaccgtcgcc
    12661 gacttcgggc agctgaagta cgtccgctgg gcccaggcgc tcgtcgcgct gaaccagacc
    12721 gtcaaggcgt agcacgtagt cccgggtccg cgtgttcggg gttcgtgggc ctgaatgaaa
    12781 aaggccgtcc ccctcaccct tcggcagggt gagggggacg gcctgtgtgg tgcggaggac
    12841 tactccgact cgccctccag gttgccttcc gtgtccaggt agacctggcg gagggattcg
    12901 aggatctgcg ggtccggctt ctcccacatg ccgcgggact cggcctccag caggcgttcc
    12961 gcgatgccgt gcagggccca ggggttggcc tcctccagga aggcgcggtt cgtcgggtcc
    13021 aggacgtacg tttccgtgag cttgtcgtac atccagtccg cgaccacgcc cgtcgtggcg
    13081 tcgtagccga agaggtagtc caccgtcgcc gcgagctcga aggcgccctt gtagccgtgg
    13141 cggcgcatcg cctcgatcca cttggggttc acgacgcggg cccggaagac gcgcgaggtc
    13201 tcctcgacga gggtgcgggt cttgaccgtt tccgggcggg tggagtcgcc gatgtaggcc
    13261 tccggagcgg tgccgcgcag ggcgcggacc gtggccacca tgccgccgtg gtactggaag
    13321 tagtcgtccg agtccgcgat gtcgtgctcg cgggtgtccg tgttcttcgc cgcgaccgtg
    13381 atgcgcttgt aggccgtctc catctcgtcc cgggcggggc gcccttcgag gccgcggccg
    13441 tacgcgtagc cgccccacac cgtgtagacc tccgcgaggt cggcgtccgt acgccagtcg
    13501 cgggagtcga tcagctggag gatgccggct ccgtacgtgc ccgggcgcga gccgaagata
    13561 cgggtcgtcg cgcggcgctc gtcgccgtgc tcggccaggt ccgcctgcgc gtgcgcccgg
    13621 acgaagttgt ccgcggcggg ctcctcgagg gacgcggcca gccgtaccgc gtcgtccagc
    13681 aggccgatga cgtgcgggaa cgcgtcgcgg aagaagcccg agatgcggag ggtgacgtcg
    13741 atgcgggggc ggccgagctc cgcgagcggg atcggctcca ggccggtgac gcggcgcgag
    13801 gcctcgtccc agaccgggcg gatgccgagg agggagaggg cctcggcgac atcgtcgccc
    13861 gaggtgcgca tcgcgctcgt gccccacagg gacaggccga ccgaggccgg ccactcgccg
    13921 ttgtccgtgc ggtagcgggt gaggagggac tcggccaggg cctggcccgt ctcccacgcg
    13981 aggcgggagg ggacggcctt ggggtcgacc gagtagaagt tgcggcccgt cggcaggacg
    14041 ttcaccaggc cgcggagggg ggagccggag ggacccgccg ggatgaagcg gccgtccagg
    14101 gcggcgatga cgtgggcgat ctcgtccgtg gtgccggcca gccgcgggac cacctcgcgg
    14161 gccgcgaagg acagcaccgc cgcgacgtcc gcggcgtggt ccgccgccac cgtcggtacg
    14221 gcgtccaggg accagttcgc gtcctccatc gcctggacca gggcgcgggc ctgggcctcg
    14281 accgcgtccg ccgaggtgcg ggttgccttg gactcgtcca ggccgagcgc ctcgcgcagg
    14341 cccgggaggg ccgtcgtacc gccccagatc tgacgggcgc gcaggatcgc caggaccagg
    14401 ttgacccggg cctcaccggt cggcgcaccg cccaggacgt gcaggccgtc gcggatctgg
    14461 gcgtccttga cctcgcacag ccagccgtcg acgtgcagca ggaagtcgtc gaagccgtcg
    14521 tcgtccggac gctcctccag accgaggtcg tggtcgagct tcgccgcctg gatcagggtc
    14581 cagatctggg cgcggatggc cgggagcttc gccgggtcca tggcggagat ctgggcgtac
    14641 tcgtccaggt gctgctccag gcgcgcgatg tcgccgtacg actccgcgcg cgccatcggc
    14701 ggcaccaggt ggtcgaccag ggtggcgtgc acgcggcgct tggcctgggt gccctcgccc
    14761 gggtcgttga ccaggaacgg gtagatgagg ggcaggtcgc cgagagccgc gtcgggcgcg
    14821 caggcggcgg acaggccggc gttcttgccg gggagccact ccaggttgcc gtgcttgccc
    14881 aggtggatca tcgcgtcggc gccgaagccg ccgtcctgcg cgcgcgcctg gatccagcgg
    14941 tacgcggcca ggtagtggtg cgagggcggc aggtccgggt cgtggtagat cgcgatcggg
    15001 ttctcgccga aaccgcgcgg cggctggatg aggatgagga ggttcccgcg gcgcagggcg
    15061 gcgagcacga tgtcgccctc cgggttggcg gagcggtcca cgaacatgtt gccgggggcc
    15121 tcgccccagt gctcggtgac gctgtcgcgc agctcggccg gcagttcggc gaaccaccgc
    15181 ttgtagtcgg cggccgggat ccggaccgga ttgcgggcca gctgctcctc ggtcagccag
    15241 tcctggtcgt ggccgccggc ctcgatcagg gcgcggatca gctcgtcgcc gtcgcccgag
    15301 accagacccg ggatgtcctc ggtcggcccg aagtcgtagc cgccggcgat gagggtgcgc
    15361 agcagctcca cggcgctggc cggggtgtcc aggccgaccg cgttgccgat gcgcgagtgc
    15421 ttcgtcgggt acgcggagag gaccagcgcg accttcttgt cgcggcggtc gatgtgccgc
    15481 aggcgggcgt ggcgtacggc gatccccgcg acccgggcgg cccgctcggg gtcggccacg
    15541 taggcgggca ggccgtcctc gtcgatctcc ttgaaggaga acgggacggt gatcaggcgg
    15601 ccgtcgaact cgggcaccgc gacctgcgtg gcggcgtcca gcggggacag gccctcgtcg
    15661 ttctcctccc aggcggcgcg cgagccggtc aggcacaggg cctgcaggat cggcacaccg
    15721 aggccggcga gcgcgcccgc gtcccaggac tcgtcgtcgc cgcccgccga ggcggtggcg
    15781 ggcttggtgc cgccggccgc gaggacggtg gtgacgaccg cgtcggccga ctccagggcc
    15841 gcgatcagct ccggctcggg ggtgcgcagg gaggacacgt acaggggcag tgcctgggcg
    15901 tcgtgggcct cgatcgcgtc gcacagggcg tgcacgaagg aggtgttgcc gctcatctgg
    15961 tgggcgcggt agtagagcac ggcgatccgc ggccccgcga tggtcccggg cgtacgctcc
    16021 agcgggcccc aggtggggga ggcggccggg ggctcgaagc cgtggccggt cagcaggacg
    16081 gtgtcggaga ggaaccgggc cagctgctcc aggttggccg ggccgccgtg cgcgaggtag
    16141 ccgtgggcct cggccgcgat gccgatgggg accgtggagg cctccatgag ctgggcgtcc
    16201 ggggcctgtt cgccggtcag gaccacgacc gggcgggtct ggccgggggc gaggagcagg
    16261 tcgaggccgt cctgccaggc gcggaggccg ccgaggaggc gtacgacgac caggtcggcc
    16321 ccgtcgagga ggccgggcag gtcgtcgagg gggagacgtg aggggttcgc gaaccggtac
    16381 gggacggggc cgtccgccgt gttcgctgcg cgggcgctga gcagatcggt gtcggacgtc
    16441 gacagcagca ggatcatgcg gcggcaggcc ttcctcgggg tttccgcgcc ccgggcagtg
    16501 tgaggacagc gggagttcct gactcacccc gggcgcggga tcgctccgcg gggttcacag
    16561 tggcgggacc gcgccggaat cgcaccgggc ttcctcccat gtcgccgtcc tcggcgacgg
    16621 cgggccgtgt ggtccgccgg aaggtcatct taggggcgga gtggtcccgt gggggcgggc
    16681 ggggtggtgg cggggctggc gtggccgggt gcggtggcgc tgccggggct ctgcgtctgc
    16741 cggcggccgg ggcggggcgg ggtcgggtcg aagggggcgg gaccggagcg gccgggtgcg
    16801 gcgccgctgt cggggctctg ccccgggccc cgcgcctcaa acgccggcga ggctggatgg
    16861 gcggggctct gccccgggcc gcgcctcaaa cgccggcgag gctggatggg cggggctctg
    16921 ccccgggccg cgcctcaaac gccggcgagg ctggatgggc ggggttctgg tccgggccgc
    16981 gcctcaaacg ccggcggggg tggatgggtg gggtcggagt tgctggtcgg ggtggtgatg
    17041 gacacaggtc ccgggggtgg gatcgtgggt atgctcgcgg ccatgcccca gcccccttcc
    17101 gccgcatcgc gggacgaacc cgtcatacgg cagcgcggtg acgcctgccc cggcgcgctg
    17161 cggctgcacg cggcggacga cgggttcctc gcgcgggtcc ggctcccggg cgggctgctc
    17221 accgggccgc aggccgcggc gctggcgctc gccgccgacc gcttcggcga cgggcacctg
    17281 gaactgacct cgcgcggcaa cgtacagctg cgcggactgg ccgacggctg cggcggcgcg
    17341 ctcgccgagc tgctcgacgg agccggcctg ctccccgcgc cgagtcacga gcgggtacgg
    17401 aacatcgtgg cgaccccgct gtccgggctg gagggtcccg accggcccga tgcgctggcc
    17461 tgggccatgg agttcgaccg gctgctgtgc gcgagccctt gggcggccgc gctgtccggg
    17521 cggttcctgt tcgccttcga cgacgggcgc ggggacgtgg cctcgctcgg ccccgacgtc
    17581 accgtcctcg gccgccccgc gggccgggcg ctcgtccggc tcggccgggc cgccgacgcc
    17641 gtggagctgg ccgggccgga cgcaccccgg gcggccctgt cggccgcccg gtacttcctc
    17701 gacgccgcgg ccgaagcggg cacccaggcc tggcgggtgt ccgaactgcc cgacgaacac
    17761 gccctgggaa cagtcgagtt cgtccggcgc ctcgaggctg tggggatcgc cgccgcggcc
    17821 gtcggcgccg tggactggcc gtacgcgccg gcgccccggc ccccgggcgc gggcacccgt
    17881 gcccgggcca cgctgtgcgt gctgcccccg ctcggccggg tcgactccgt ccagtggcgg
    17941 gtcctggcgc aggtcgcgca ggaggggggc ggcgagctgc gcgtcacccc gtggcgcagc
    18001 gtcatcctgc cctcggtgca cggggacgcg cccgcccgca tcgaggacgc cgggctggtc
    18061 gtcgcccccg acagcccctg ggagaccgtc accgcctgca ccgggcggcc cggttgcgcg
    18121 aaatccctcg cggacgtacg cgccgacgcg cgggccgtcg tcgaccgggc ccgcggcccg
    18181 ctgcccgtgc actggtccgg ctgtgagcgc cgctgcggcc atccgcgcgg caccgcctgg
    18241 gtggacctgg tcgccaccgg caccggatac cggatcaccg cccccggccg ccccgtacgc
    18301 gacgacgtac ggccccccga acttgccgcg gcactcgcgg acgcccgcac cgaccccgac
    18361 gtagtgaaga aatgagcgag tacaccgtgt ttgagtacga gaaggacggc gcggccatct
    18421 accgccagtc ctttgccacg atccgcgccg aggcggacct ctccggactg cccgacacgg
    18481 tcgcccaggt cgcggtgcgc atgatccacg cctgcggaat gaccgacctc ccgcaggacc
    18541 tcgggtacac ccccgaggtc gtgctgcgcg cccgtgcggc gctggaggcg ggcgcgccga
    18601 tcctgtgcga cgtacagatg gtcgccagcg gtgtcacccg taagcggctg cccgccgaca
    18661 acgacgtgat ctgcacgctc tccgacccgg ccgtaccgga gctcgccgcg cggatgggca
    18721 ccacgcgcag cgccgccgcc ctggaggtct ggcgcgaccg cggcctgctg gagggctcgg
    18781 tcatcgccgt gggcaacgcg ccgaccgccc tgttccggct gctggagatg atcgaggagg
    18841 gcgccccgcg ccccgccgcc gtcatcgggg tcccggtcgg cttcatcggc gccgccgagt
    18901 ccaaggacgc cctcgccgcg cacccctcgg ggctcgacca cctgatcgtg cgcggccggc
    18961 gcggtggcag cgccatggcc gccgccgcgg tcaacgccat cgcgagcgtg gccgaatgag
    19021 cgccgccgag gccaaggggc ggctgtacgg ggtcgggctc ggccccggcg acccgtcgct
    19081 gatgaccctg cgcgccgtcg aggtgatcgc cgaggccgat gtggtggcct accacagcgc
    19141 ccgccacggc cgttccatcg cccgctcgat cgccgcgaag cacctgcgcg ccgaccacgt
    19201 cgaggaaccg ctggtctacc cggtcaccac cgagaccacc gaccaccccg gcggctacca
    19261 gggcgcgatg gaggagttct acgaggccgc cgccgcccgc ctcgccgccc acctggacgc
    19321 cggccggacc gtcgccgtgc tcgccgaggg cgatccgctc ttctacagct cgtacatgca
    19381 catgcacaag cggctcgcgg accggtacga gaccgaggtc atccccggag tcacctcggt
    19441 gagcgccgcc gccgcccggc tcggcacccc gctcgtggag ggcgaggagg tgctgaccat
    19501 cctgcccggc accctgtccg aggaggagct caccgcccgt ctcgccgcca ccgactcggc
    19561 ggtcgtgatg aagctcggcc ggaccttccc cgccgtgcgc ggcgcgatgg agaacagcgg
    19621 ccggctcgcc gaggcgcggt acgtcgagcg cgccaccatg gccggcgagc gcaccggccg
    19681 cctcgccgac acggacccgg agtccgtccc gtacttcgcc gtcgccgtgg tccccagccg
    19741 catcggcaac ccgggcagcg tgccgtccgg cccgggcgag gtcgtcgtcg tcggcaccgg
    19801 cccggcgggc ccgctgtggc tcaccccgca gacccggcgc gcgctggccg acgcagaggt
    19861 gctggtcggc tacaccacct acctggaccg ggtgcccgtc aggccgggcc agatccggca
    19921 cggctccgac aacaaggtgg agtcggagcg cgccgagttc gccctcgacc tcgcccggcg
    19981 cgggcagcgg gtggccgtgg tctccggcgg cgaccccggt gtcttcgcca tggccacggc
    20041 ggtcctggag gtggccgggc aggcggagta caaggacgtg ccggtacggg tcctgccggg
    20101 ggtgaccgcg gccaacgcgg ccgccgccgc ggcgggcgcg ccgctcggcc acgactacgc
    20161 cacggtctcc ctctcggacc ggctcaagcc ctgggaggtc atcgcggagc ggctgcgcgc
    20221 ggccgccgcg gccgacctgg tactggccct ctacaacccc ggctcgcgca gccggacctg
    20281 gcaggtggcc caggcccgtg agctgctgct ggagctgcgc tcgcccgaga ccccggtggt
    20341 cgtcgcgcgc gacgtgggcg gcccggagca gaccgtacgc atcgtcacgc tcgccgaact
    20401 ggagccgtcc gaggtggaca tgcgcacgat cctgctgatc ggctcctcgc agacgcaggt
    20461 caccgagcgg gccgacgggt cgaggatcac ctggacgccg cgccgctacc cgtgatgtga
    20521 cgtgatgtga cccgagggcc gagtcgaaag ggcggtgccg gtaccggcac cgccctttgc
    20581 cgtccctgtt gaatagacgc aacgtctagt ctagtctcgc gtcgtgggca ccacgcgctc
    20641 cgtcccgtcc gggccgccgt caccccacct cccatcccgc tcccgtcgag aggccgttca
    20701 gtgctggacc aaccccgtcg gccgggcagc ggcgcggccg cggctgtcgt cgccttcgcc
    20761 ttctggatca ccatggccgg cacgaccgtg cccaccaccc tgtatccgct ctacggcgag
    20821 gccatgggct tctcgccgat caccgtgacc gcgatcttcg ccgtgtacgc cgtcggggtc
    20881 gtcgtcggac tgctcctcct cggccggctc tccgaccaga tcggcaggcg cccggtcctg
    20941 ctggccgcga ccttcctgtc ggtctgcggc gccctcgtct tcctcgtggc cgacagcgtc
    21001 ccggccctct gcgtcgcccg cgtgatctcg gggttctccg ccgctctcat caccggagcc
    21061 gccacggcat cactcaccga actcctcccc ggggacagcc ggatcaagcc cgccaccgtg
    21121 gccctcttcg ccaacatggg cggcctggcg agcggcacgc tggcggccgg agtcctggcc
    21181 gacctcgcac ccgagcccct gcgcacgccg tggatcgtca cgctcgtcct ggctgcgctc
    21241 gcggtgatcg gtgtggcatc gacacgggag acatccgcac accggtccgg cttcaccttc
    21301 cacgcgcggc tgctgcacgt gcccgcggag atccggtcgg acttcctgcg ctcggcgacg
    21361 gcagcgggca cgggcttcgc ggtcctcggc gtactcaccg ccgtcaccgg gctgttcatg
    21421 ggccaggtgc tccacgagtc cggccacacc ctcgccgggc tggtggtctt caccgccttc
    21481 gcctgtacgg cgctggggca actgctggtc cgcgccgtcc ggccgggagc ggtactggtc
    21541 gtcgcctgcc tcgggcttat gctcgcggcc gccctgatgg cggccgccat ggccgcgcag
    21601 gccttcgcgc ccctgctcat cggggccgcc gtgaacggcc tggccaccgg aatggcggtg
    21661 tcccacggca tccgggacat caccacccgc agcgcacccc ggcaccgggg cgcatccgtc
    21721 tccaccttct tcgcgatcct ctactcgatg ctcgcggtac cggccatcgg cgtcggcgtg
    21781 ctcatccgcg ccacgagcct gcggcccgcc ggcgaggtct tcagcgcagc ggtggccgta
    21841 ctcgccctcg tggtgctgct gagcctggtc ctgcgccgga agccggcggg agcggccgcc
    21901 tgatcgggct gcttcccgcc acctcggcgt gtgccagaat cggccggatg gccggacggc
    21961 cgatcagtca gaaccgaggg gtgaaggacc atcagcgccg cacggaacac cgagaacccg
    22021 cgtgtccagc ccgccgtggt cagccggacc ggcccccggc gcagcgagag cgtccgcctc
    22081 gccgtgctca acgccgcgga cgacctgctg gtggagcagg gcttcgcggg aaccaccatc
    22141 gagggcatcg cgacccgggc gggggtggcc aagcagacca tctaccggtg gtggaagtcg
    22201 aaggtcgaca tcctgct
//
