LOCUS       NZ_CP019724            26329 bp    DNA     linear   CON 01-JUN-2024
DEFINITION  Streptomyces pactum strain ACT12 chromosome, complete genome.
ACCESSION   NZ_CP019724
VERSION     NZ_CP019724.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces pactum
  ORGANISM  Streptomyces pactum
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Streptomyces pactum ACT12 Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2017) College of Life Sciences, Northwest A&F
            Unversity, No.22 Xinong Road, YangLing, Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2016
            Assembly Method                   :: SMRT v. 2.3.0
            Assembly Name :: version 2.3.0 of the PacBio Single Molecule Real
            Time
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002005225.1-RS_2024_06_01
            Annotation Date                   :: 06/01/2024 05:58:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,315
            CDSs (total)                      :: 7,221
            Genes (coding)                    :: 6,992
            CDSs (with protein)               :: 6,992
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 229
            CDSs (without protein)            :: 229
            Pseudo Genes (ambiguous residues) :: 0 of 229
            Pseudo Genes (frameshifted)       :: 84 of 229
            Pseudo Genes (incomplete)         :: 195 of 229
            Pseudo Genes (internal stop)      :: 15 of 229
            Pseudo Genes (multiple problems)  :: 62 of 229
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:20:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4616123
            Orig. end                         :: 4642452
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019724.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Northwest A&F Unversity.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26329
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="25"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26329
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26329
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16329](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16329)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(484..498)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     gene            complement(1484..2164)
                     /locus_tag="B1H29_RS19590"
                     /old_locus_tag="B1H29_19630"
     CDS             complement(1484..2164)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061649.1"
                     /locus_tag="B1H29_RS19590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19630"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_055421977.1"
                     /transl_table=11
                     /translation="MTQRCFDDEEDDVPEWEDRVKANVAGEVRRRRKEMGWSAQDLADR
                     CERLGYPIPRNVIANMESGRRANLPLVDVMVLAAALETYPVCLIFPVGYVERTQELPFQ
                     HLVPTWDALRRFTGDEDMPSYDAGLVPDFEAHDSLVRTALAALEEEERARFAARTAGNR
                     AQQEEAERKQAKYADEAISAKYNLRHLRRDIREEGAIPPHLPLALSDVDPPEPDPNTTP
                     EERV"
     gene            2261..2500
                     /locus_tag="B1H29_RS19595"
                     /old_locus_tag="B1H29_19635"
     CDS             2261..2500
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961488.1"
                     /locus_tag="B1H29_RS19595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19635"
                     /product="hypothetical protein"
                     /protein_id="WP_055421976.1"
                     /transl_table=11
                     /translation="MRDDATAGRSTSSKGMSREELLALPVSVDLDTSNRALGLGRSKGY
                     ELAKRGEYPCKVLRLGNAYRVVTANLLELLGLAA"
     gene            2734..4014
                     /locus_tag="B1H29_RS19600"
                     /old_locus_tag="B1H29_19640"
     CDS             2734..4014
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115769.1"
                     /locus_tag="B1H29_RS19600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19640"
                     /product="DUF3631 domain-containing protein"
                     /protein_id="WP_167392545.1"
                     /transl_table=11
                     /translation="MEHAGAEHYSDSNTPSWPPVAVPGQPVDGTASPSPKAPASPVEAP
                     TASPDSEGAELLVGLRAQIKRYVAMPGEEALTAVTLWIAATHLQRAWQHAPRLAIVAPE
                     KRCGKSRLLDVVTETVRNPLITVNASAAAIFRSIDDEDPPALLVDEADTLFSTVKAAEK
                     NEEVRGLINAGHQRNRPTLRVTGPEHKPTAFPTFAMAALAGIGDLPDTVMDRSVVIRMR
                     RRADGEEVAHFRTHRDTPALHTIRDRLTAWLQPLYAQALEMEPAMPVEDRAADTWEPLV
                     VIADLAGGEWPALARTACRVMTDYEAGQDEEGGLRTRLLVGIRRAFAAENDPAVLGTKR
                     LLEALNADKEAPWAEYGPNGLTPRGLQLLLKPYGISSANRRFPDGTQAKGFARNQFLDT
                     WARYCPEPAPAAEPAQPSAEPLPGSAA"
     misc_feature    complement(2767..2782)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.16"
                     /tool="antismash"
     gene            4227..4979
                     /locus_tag="B1H29_RS19605"
                     /old_locus_tag="B1H29_19645"
     CDS             4227..4979
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073833.1"
                     /locus_tag="B1H29_RS19605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19645"
                     /product="DUF2637 domain-containing protein"
                     /protein_id="WP_055421975.1"
                     /transl_table=11
                     /translation="MSARITATAAIRVGIALLAIFAFALSYDALRQMAVAIHIRGLLTY
                     VFPLVIDGFIAIGVGALVMLRAASTWSRVYVWTLVGAATVTSIWANALHAVRLNQQTRQ
                     GDGLRLDDFTVGGLSAIAPLALAGAVHLSIVVHRQPTARGPADVARGAADVAPDTAEVA
                     EGPQSSVEPQDHEPSHISPERLALARTAPLGRNGRASRRHIEATFRSRDLTIGRTEADK
                     LKDILQAELDEAVSPQQREPETASASAV"
     gene            5111..5755
                     /gene="mobC"
                     /locus_tag="B1H29_RS19610"
                     /old_locus_tag="B1H29_19650"
     CDS             5111..5755
                     /codon_start=1
                     /gene="mobC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073834.1"
                     /locus_tag="B1H29_RS19610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19650"
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_055421974.1"
                     /transl_table=11
                     /translation="MHDPYHELPISEQEMATGLNSAARYPVGPSKGRSNGGPSAPGVAE
                     GLGHQEVPEEDKLVETPAVPLPRATDAAALHRVARRRQHEPVQRKERVDVRYSAEEKTA
                     ILAKARSLNIAGAHYVGAVVMAHLHGDLALSGQRTPLDDYIDELTALRREVARIGHNIN
                     QIAKKLHSGGHPHPGDSAMLAQVEPALDAVGATVRHIASAANQAVAKKRAR"
     gene            5752..7443
                     /locus_tag="B1H29_RS19615"
                     /old_locus_tag="B1H29_19655"
     CDS             5752..7443
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825832.1"
                     /locus_tag="B1H29_RS19615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19655"
                     /product="mobilization protein"
                     /protein_id="WP_079160322.1"
                     /transl_table=11
                     /translation="MIAKISGGKDTAGLIRYLFDTKKAKDHTDPHLVASWDGFAPDPGR
                     TDDFDATKRLLVADLDLHVKQARRLGRTPEKHTWHCSIRAAESDRHLSDEEWADIARRV
                     VAATGIAPDGDPDGCRWVAVRHAPDHIHIAATKVRADLRTARHWNDYLTADRELAAIEK
                     EYDLFQVIRGDRTAAARPTRAEQEKARRAGHDTTARERLRATVRTAVAAASTIEEFVSL
                     LSHLDGVLVEVVHFPSGDVRGYKVAVADDAQGPIWYSGSKLAPDLSLPKIQERLAAMGP
                     QPIDQSGRRRPNPWYQATAAAERIAHHLDQPDDGASQAHLAAFGEALDAVVLVTPQAVR
                     PQLREAATAFERATRSRIHAEHHHARALRGAVRAMLREPAPKDGAVLAMFLDAAVLVVI
                     AAARWHQLHHHDQQVAAARETLLHLQAAYGQAAAAPLAALAQRRPPQQTVDRHVRHLRQ
                     AVPNHAEQIVEDPAFGALTAALAEAEAVGHDPQQLLQQAADQRALDDADSPARVLTWRI
                     QRLGARPAPSARARAAQARSRAQSPHAPVHVAATPTTLLPPRTRRR"
     gene            7642..8718
                     /locus_tag="B1H29_RS19620"
                     /old_locus_tag="B1H29_19660"
     CDS             7642..8718
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B1H29_RS19620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B1H29_19660"
                     /product="hypothetical protein"
                     /protein_id="WP_159027839.1"
                     /transl_table=11
                     /translation="MTIKRGRKGELGLEVLPLVHMALPEPDGQTLLRDRHPETMAAIGH
                     ALRASLDNISRLQGQQAQYAFEAVVVALGGVRLIKTEDSGSYYFDDADGELRPPDFRII
                     LRDGTVLLVEVKLVPPGKEKKVKVRAKDMEATEAYARATGGRLLYAHYWSGPNLWTLVP
                     PSAFQRDVGQQRLTVSAAMMANEMGILGDAFLGGKPPLTVSVLMDTGMEKSVEAEDESD
                     QRLMTTAGVELSSAGKVIKDPAELKLAWFLAWHSGWIPTQRAQFDSLGRVARINYDFAP
                     DVDKDQMREIAKQGFAFFGALSTLYTARFRRATTTDGGDIRALSEEPRPALMAQLVPED
                     YWEQDRILGLWKFNLKPQ"
     gene            complement(8776..9912)
                     /locus_tag="B1H29_RS19625"
                     /old_locus_tag="B1H29_19665"
     CDS             complement(8776..9912)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436871.1"
                     /locus_tag="B1H29_RS19625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19665"
                     /product="hypothetical protein"
                     /protein_id="WP_079160323.1"
                     /transl_table=11
                     /translation="MDPHGLTAQRFPLVARFRPAYLPLPERVRALVDLADTAVKKADQG
                     LASAVYNQAALIASDLALPDLAREMCHQHAAAYLHACPLPGMSAIRGLEPVVNLARLQI
                     RAGHADEGRQRLLDLYKAVETGTAARFEGVNVPADLTAASEDRQEVRAWLWRVLLADGT
                     RTLTTEGRWAEALVHIEAHHGIGQRMLDGRQVAVLAALVANDTAGAAGLLADTMPGDPW
                     EQAVTACLTVLCRRDAGQSIDGHLAALVTAYSGRKAEPGMTVFDIRLGLTVLDAIGSAE
                     ALAAHRIVEDLHRRTTDAEDGYAARENLAHPLFTEIATARQVQDCRALVRTCALDAGIL
                     PDELQRELAAALRASDSVIRGSLEQPSGPGSKILPGRA"
     gene            complement(10001..12082)
                     /gene="fxlM"
                     /locus_tag="B1H29_RS19630"
                     /old_locus_tag="B1H29_19670"
     CDS             complement(10001..12082)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543781.1"
                     /locus_tag="B1H29_RS19630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19670"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_055421970.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5e-28, bitscore:
                     97.2, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 1.8e-45, bitscore: 154.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPDRWQQHNITFGDRETARHTIAERLGPALIEAEADGQLTGWWF
                     MNKQPWPLRYLADKPSPAIESLLSDLIDDGVAMSCLPCVYEPETDAFGGTEAMAAAHEL
                     FHSDSRHLLTYQPSPMHLGRRETAVLLASALMRGAGLDWFEQGDVWAKVAALRPATNPP
                     PPERAAELAPPMRKLMTADAHNLCHPGSPLHAHKEWVTAFERTGATLADLAARGTLTRG
                     LRAVIAHHVIFHANRAGLLRNDQSALSHIAREVVMGTSDHTASPTEATADIDSVSAVNT
                     DTITTPTADAERLRNALVDQLRADGHARTSAVETALRTVPRHVFVPEASLEDAYANAPV
                     HIKYDTDGTSISCASQPGVVALMLDQLEAQPGERILELGAGTGYNAGLLAHLVGENGHV
                     TTLDVDDDLVEGARTHLAAAGVTNAEAVTRDGALGYAETAPYDRIIATVGAHGVPHAWL
                     QQLAPGGRLLVPQRLKGTVSRSIAYEQRDGRWVSLGSEMNTFMPLRRGIADDDRRVIPL
                     STDGTVRLQAPAGLSIDADALAGVLDQPRTEEWTGMTVRAMESPEWMELFVTCSLPSGL
                     VRMLFPQSAKGTLLTEDPYPSSTAVVDKGAVTYLARRLSKEKTPEGDKLWEFGVIGHGP
                     GSDELVARVADAIRTWDRDYRDREATFEIQPLDAPEIEQRPGRFALDTPLNRIVVDWR"
     gene            complement(12104..13378)
                     /locus_tag="B1H29_RS19635"
                     /old_locus_tag="B1H29_19675"
     CDS             complement(12104..13378)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543780.1"
                     /locus_tag="B1H29_RS19635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19675"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_055421969.1"
                     /sec_met_domain="LANC_like (E-value: 7e-44, bitscore:
                     148.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAHPALGLVHAIAARLADPDTVRLASRTLTSDRQHLAYGPPGIA
                     LLHIELAANGHGPWYRAHDWLAAASRQPLTSGPDSHPFYGVPAFAHALTCAADHLPGSY
                     QRALDAMDRQIAVDVGRRLDTAHRRIDAGRLPQLAEFDTIRGLTGYGAYLLRRDPGSST
                     MRAVLDYCVRLTEPITHHGETLPGWWAETGPSGSPDDRFPGGHANTGMAHGIGGVLALL
                     ALAARNGSVTDGHHAAVRTILAWLDRWKQKADGGPDWPYWITQGELRRGRLAPSAPRRP
                     SWCYGTAGLARAQQLAALALGDASRQIDAENALVAALTDPEQLKATTDNGLCHGSAGLA
                     HTAARTADDAHPSTADKLRAAIPALLAAVIPPSTDPELMATALIQDKEGGPGLLDGAAG
                     IALALLAPSTAAPPQSAWDACLLIA"
     gene            complement(13375..16329)
                     /locus_tag="B1H29_RS19640"
                     /old_locus_tag="B1H29_19680"
     CDS             complement(13375..16329)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543779.1"
                     /locus_tag="B1H29_RS19640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19680"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_055421968.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.1e-198,
                     bitscore: 660.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 6.1e-21,
                     bitscore: 73.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.3e-23, bitscore:
                     80.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAWLRAVWANKDVAEALQHSSPVLAAQVRALCTAEHPARRDVQRA
                     ALSVARYLLRAQHRATPFGLFAGVATAEFGPQARAGWGEEHVAVGRAGAEWLAAVVAWL
                     ESCPDLLERLPVVANNTVTYRGDRLIVPFQPDVQDDRTRAVEASLALTGPVRAVLAGTR
                     APIRFGTLVDKLQAEFPEAGPEKARHLLAELIRRRVLITGLHAPSTETDALGYLVGQLD
                     AIDAGSLAPVAETVRELHAIRAGLEKCTTHGGRDRVAAQMRDLAPGLRRHPLALDLRLD
                     AQIVLPETVAREIERAALILTHLSIRPYGTAAWNEYHQRFYERYGIGTMVPLAEVVADS
                     GTGYPDGYPGAPAGARRPRVSARDDALVGLAQAAVLDGRDEVILTDQQIEALDVGPDEP
                     RLPPHLEIGVRVHAASLEELQRGRFRLEVMSVSRGAGVSTGRFLSVLALADREALVAEL
                     ADLPAADGNTMPAQLSFPPLLPESAHVTRSPQVLPTVISLQEHRAPQDTVLTSEDLAVG
                     CDGRRMYLAVPERGHRVEAIGMHALNLHTHTPPLVRFLTELSRAQCAQVTVFDWGAAAA
                     MPFLPRLRYGRIVLTPARWRLEASELPCHARSLVEWDAAFAAWRARRRLPRRVYLVEDD
                     RRLFLDLDEAGHRALLRRHLDRTRLTVLVEAPEPEAYGWCGGRAHEIVVPLKATRPPTW
                     PPLPTPSRARVLSATQMQTPAASSVLLAALYCDPRRQDVLLSRHLPGLLEQLGNPPWWF
                     IRFRDPDQHLRVRIALPDPEAFAGTARTVSAWADEVRSIGLLADLRYPTSYREMGRWGS
                     GTAWEAAEEVFRADSRAILAQLAQPQRPGQRTLMAAHTVAIASAFLGSTAAGMRWLIDH
                     VPPKTPAPVPRPQFTAAVRLADPSDNWAAMRHVPGGDAIVSGWADRDTALTTYRPHLPG
                     PDTEGIAVDDVLTSLLHVHFVRHVAVNFPEEEVCLYLARAAALAWTARTRGRAS"
     aSDomain        complement(15709..15984)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B1H29_RS19640_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.30E-23"
                     /identifier="RREFam001.1"
                     /label="B1H29_RS19640"
                     /locus_tag="B1H29_RS19640"
                     /protein_end="207"
                     /protein_start="115"
                     /score="73.7"
                     /tool="antismash"
                     /translation="VVANNTVTYRGDRLIVPFQPDVQDDRTRAVEASLALTGPVRAVLA
                     GTRAPIRFGTLVDKLQAEFPEAGPEKARHLLAELIRRRVLITGLHAP"
     gene            complement(16548..16727)
                     /locus_tag="B1H29_RS19645"
                     /old_locus_tag="B1H29_19685"
     CDS             complement(16548..16727)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825826.1"
                     /locus_tag="B1H29_RS19645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19685"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_016825826.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 5.1e-13, bitscore:
                     47.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSTVVPSRTEVRPQIPGASDGFDLDVSLVEIADPAGLVNLTDD
                     NCGSTCGACTTNVA"
     gene            complement(16917..17105)
                     /locus_tag="B1H29_RS19650"
                     /old_locus_tag="B1H29_19690"
     CDS             complement(16917..17105)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337811.1"
                     /locus_tag="B1H29_RS19650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19690"
                     /product="hypothetical protein"
                     /protein_id="WP_055421967.1"
                     /transl_table=11
                     /translation="MEWPWITGDCWLGCGRTGVLVMWLGPVQWDGQHAPFYACEPCLDR
                     LKAQALAYFMERRPASA"
     gene            complement(17333..17779)
                     /locus_tag="B1H29_RS19655"
                     /old_locus_tag="B1H29_19695"
     CDS             complement(17333..17779)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000003.1"
                     /locus_tag="B1H29_RS19655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19695"
                     /product="ATP-binding protein"
                     /protein_id="WP_055421966.1"
                     /transl_table=11
                     /translation="MTSLRTPVEALSVGHPTYSQTFPCEPSTAEIGRDLVRAVLGVWHI
                     DGLADRAALIVTELIANAARHTPCPEIRLTVGRPSATRVRVGVVDREPTRLPILGQAGD
                     DDESGRGLLLVDAVADRWGYDLHGSGRRPWGKEVWAELRTGGGE"
     gene            18021..19304
                     /locus_tag="B1H29_RS19660"
                     /old_locus_tag="B1H29_19700"
     CDS             18021..19304
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000004.1"
                     /locus_tag="B1H29_RS19660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19700"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_079160324.1"
                     /transl_table=11
                     /translation="MDTTRNTVLEAWMTEHGYSSNSLAEAVNSAIERLTGRPGGLDGSS
                     VRAWKAGRVTWPKSAARKALEDVTGLPAVALGFVPRSRPSSTPAPPQQEDPDMKRRTLV
                     GSIAAAAAAAAAPGTTSPRRIGMSDVNRLNKRFAEIIASDHRHGGQLGIEQRAAALADE
                     ALNLQNAGSATQRVRSNLYASAAAFRSSAMWAAIDGRRYDIAKAHMREAQALAEMSGDQ
                     AIKFRIWSHAGTMYRHMGRPADAFAANDVARNLHLTRRDPLFASLGLARQGAIHGTAQD
                     RTGTRRAFEQAQDAMLRADPADYRPVWMLAFYDQAELDSLALSAHLALGDYSTAEYHAH
                     RCLSALRPHMIRSRAITTTRLAHAQLAQGAPDAATATAMKVPAEAATQHARVTRMLQEF
                     GAALRATAPGTSTVQTWTEHTATWRMAA"
     misc_feature    18246..18248
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19301..19840
                     /locus_tag="B1H29_RS19665"
                     /old_locus_tag="B1H29_19705"
     CDS             19301..19840
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337821.1"
                     /locus_tag="B1H29_RS19665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19705"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_199832457.1"
                     /transl_table=11
                     /translation="MTTAPAIELRTFTTLDTARGDLLDVYADVRAPLLHLPNYAVTAFG
                     ERLDRHGTEPGFTAVLAYADGYPVGYAYGNTIEHGDRYWQRTSPTPAEKYTAHPAVALK
                     EIGVRQTWRKTGTARRIHDALLATRHESFVTLMVNPAAGDGKVHALYKSWGYKDIGQSQ
                     PSPASPVLAVMIRTIR"
     misc_feature    19943..19955
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.18"
                     /tool="antismash"
     gene            20058..24428
                     /locus_tag="B1H29_RS19670"
                     /old_locus_tag="B1H29_19710"
     CDS             20058..24428
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339675.1"
                     /locus_tag="B1H29_RS19670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19710"
                     /product="hypothetical protein"
                     /protein_id="WP_234393201.1"
                     /transl_table=11
                     /translation="MLLGTGHSVTVEDIDELGLGAEFTYRHGDTVEVHQLKRQNGSANT
                     WTVKSLQDKGIWENVRSHVEDGRQFRFVSLLPASPLQELADRARRSGNHDDFIKHWLTK
                     GLRDPFDDLSSSEIFESSEIAWKILRGFSISWPDEQDIVSMNGALAQLLLEGAAGSLAA
                     VGLGDLIQNSLGVTLDAPAIDSRLGTYGLSRSRLLNASGIAEQVSSVSKGWASNIEREL
                     LQPTIDRSEADQLVGLINGSNKLLLLMGHGGGGKSAALHHVYESLDADSVPLLAFRLDR
                     LEPFSSTTELGERIGVGVSPVTALAAVAGERSSVLIVDQLDAVSLTSGRMPRNFDAVAS
                     LVREASAFPAMTVVLACRKFDVENDYRIRELADAKNCAHVEVGELSDAQVTESVRAMGL
                     DANALADHQKTLLRSPLNLVLLKSIAGDEDAMAFQTTKNLFDAFWQRKLTDCRQRRDSV
                     RFNKVISTLAEAISARQRLSVPITALDADDLADDAGVLVSEHVLVRDGQQIAFFHESFF
                     DYAFARGWIERDESLVSFLLGGEQELFRRAQVRQVMNHLRELEPDRFAVETEALLTSPD
                     IRYHIKDVVLKLLGSLSDPTSREWEMVTNVQETHPAFEARLWRILQTAPWFERLDAEGV
                     IEEWLDGEDETEQGRAIEVMAGAAKSSPDRLAEILQRYKAVAEYPQWLRWVTRFSDIHQ
                     SRPLFDLLLDAVRSGQYVGMEDEVWLSAHDLGKQRPDWVVELLAAHLVDRPSAMAVDDK
                     GKIETLLDRDYSVIQLTQLAAAGAPELFCERLIPYMLGVMAKTAYEHDDSRPHRDRHFS
                     HRHPRTNIRELEDALLAGAATALRGIVERDAASARPVLESLAFDPHDTAQWLLYEALRA
                     AGSHYADWAAELLLQGTHRFISGYYAANAVWKTRELIQSTSQFMPDEAFASIEAAILEV
                     RFPWESKPTGWYPFNLLSAMQEDRLSELGRRRLGELRRKFDSDQPAEPQGVTGGAIGAP
                     INQAAAGRMSDEQWLGAIAKHNSERTDWRTHTGGAYEQSHVLQEQTKSDPERFSRLALR
                     FDESVHAAYGDAILMGLGNADALADPAPVFEAVRHIASLGHEANNRWLGSAIRKYLKTV
                     PQDIVQLIIDRATGASDPVDGSLTVQTANQEHTQGRDLYTSGINSSRGSAAEILGDLLI
                     YDADGSRTALVLPVLDAMAEDPAVTVRSCVAHVIHASMRHARPQALQAFARLINADDEL
                     LATHAVVRLMAHIGFEDLDVVKPVIERMLQSERYETRQCGGQLAALAAMHWSLVEMLDS
                     VLSGEDVASRIGAAGACAHGLSNATDTAVAQRAFEQFIDDPEDKVRGAIAEFASVVRGQ
                     RLRPLKVSLKALIHSASFEEALPQLLITLEHASDRVDDLALECGRRFVEIHGEGSGDIR
                     NRAAADARHVGELLVRAYAQATSTTSRGQVLDLLDQLLLIGAFGVADLVEKSER"
     gene            complement(25028..25417)
                     /locus_tag="B1H29_RS19675"
                     /old_locus_tag="B1H29_19715"
     CDS             complement(25028..25417)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974872.1"
                     /locus_tag="B1H29_RS19675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19715"
                     /product="hypothetical protein"
                     /protein_id="WP_055422168.1"
                     /transl_table=11
                     /translation="MPAWTTPRRLGAATALYAVFLAGWWLGQPVRSDGCLEDRLAAGAA
                     ARPAPVEPADPARYLENLGLGFDFGLLDWADDMDGYRDGEYGPSDYGYDLRGGSGTYVT
                     SGAVHTPCSYKERARLLAWLNGDRG"
     gene            complement(25484..25861)
                     /locus_tag="B1H29_RS19680"
                     /old_locus_tag="B1H29_19720"
     CDS             complement(25484..25861)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827906.1"
                     /locus_tag="B1H29_RS19680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_19720"
                     /product="hypothetical protein"
                     /protein_id="WP_055421965.1"
                     /transl_table=11
                     /translation="MNTPRRVTPRRLGAAAAIYGVFVAGWYLGQPVTPECHVDQAALDR
                     IAEEYEPVPFPTPTPTPTAYPSRYDPVSPLPSAPMPDPARGPRGGADVHLSQTFADYAV
                     ACTNDTGERPRLRAWFEGDWR"
ORIGIN
        1 atcagcttcg ctgccttctc ggcgatttcg cggtccagct cagggagcag gctcgtgtac
       61 gtgtccgagg tcagcgtgat ggtggagtgc cgcagcgtct ccttcactgc gtggatgtcg
      121 ccgccgcctc cgtgcgtgag cgtcgcggcg acgtggcgta ggtcccggag ggtgatgggc
      181 ggcaggtcgg tcgtggcgag gatgcggcgg aaggtctcgg agaccgtctc ggggtggagc
      241 caggagccgt cctctttggt gaacaccttg ccggtgtcct gccaggcggt gtcccacttg
      301 gcgcgctcct tctcctggcg ggctttgtgc tcgcgcagtt cggagatggt cgtgctgtcg
      361 agcgcgatcg tgttcgcgct gccgtccgtc ttgggctcgg actcgtaggg gtcccagccg
      421 tccaccacga tctccttggc gggcgtgatg aggccggcgt cgaggtcgat ctcgtgccag
      481 tcctggccga ccgcctcacc gcgccggagg ccgcgggtgc ccatgaggtg gaagatcgcg
      541 tacaggcggt cgccctcggc cgcgtcgagg aaggcgccga actgctgggg cgtccagacc
      601 atcaccgggc cggggatctc gcccgtctcg cgccagcgtc ggactcgctt atcggtccag
      661 agaagtggct tcgggcgctt gccggactcc aattcgacgt gggacgccgg gttgaaggtg
      721 atgagctgct gggcgatcgc tgagttcagg gccgcgcgca gggtgcggcg gatcgcctgc
      781 cgggatgccg ggccggtgat cttccggaac ggcttcatct ccgccagcct ggcccgttcg
      841 gccgcgagca gcttccgctc ggctcccacg ggtcgtccgg gcttgctcgg cttgcagcgg
      901 gcgatctgct cgcggcgggc ttcgttctcg gccgcgatga cctcgttgtc gtcggcaatc
      961 ccgtcgaaca tctccaccag gtggccgacg ttgaggcggt cgaggcgtac gtgcccgatg
     1021 cgcggcttca ggtggacgcg gatgtgggag gcgtagccgt tgagcgtggt cttgcggcgc
     1081 ttcttcgcgg cgaaccactg gtcgagccac tcgccgacgg tgagactgcc acggagggcc
     1141 aggcccgccc tgaggcggcg tcgggtctcc tcgatggcgg gcagcggggc cttctctgcg
     1201 gcgacctcct ccagcagggc gacgaggcgc tggaggctgt cggggtcatc cttgtccgcc
     1261 agggcgagaa gagcgcggac gtggtcgagg tcggcctgag ccgtcttcag ggagtcgtag
     1321 ccggcgcggt tgaaggagcg gcgggtgccg tcttcgcggg gtgggagttc ctggcgtatg
     1381 gagtacgagc cgtgcttgcg gctggagagt ttcgggcact tcttgccgag cggcttgccg
     1441 gtgtgggggt cgcggcagta gcagcggcgg tgggtggaac ccttcaaacg cgttcctccg
     1501 gggtggtgtt ggggtcgggt tcgggtgggt cgacgtcgct cagggcgagt ggcaggtggg
     1561 gtgggatggc gccctcctcg cggatgtcgc ggcggaggtg gcggaggttg tacttggcgg
     1621 agatggcctc gtcggcgtac ttggcctgct tgcgctcggc ctcttcctgc tgagcgcggt
     1681 tgcctgctgt cctggctgcg aaccgcgccc gttcttcctc ttcaagggcg gccagggcgg
     1741 tgcgtacgag gctgtcgtgc gcttcgaagt cggggaccag gcccgcgtca tacgagggca
     1801 tgtcctcgtc gccggtgaag cgccgaaggg cgtcccaggt gggcacgagg tgctggaagg
     1861 gaagctcttg ggtccgttcg acgtagccga ccgggaagat caggcagacc gggtacgtct
     1921 ccagggcggc ggccaggacc atgacgtcca cgagggggag gttggcccgg cggccggact
     1981 ccatgttggc gatcacgttg cgcgggatgg gatacccgag ccgctcgcac cggtcggcca
     2041 ggtcctgcgc gctccatccc atctccttcc ttctccggcg gacttcgccg gccacgttgg
     2101 ccttgacccg gtcctcccac tcgggaacgt cgtcctcttc atcatcgaaa cagcgttgtg
     2161 tcatgaagac acattagctt ggtcatcctg gtaggtagac gcctggagcc gaacgtgatg
     2221 accgcgttcg ccgagggctg taccgaaagg ggcgcgctgc atgcgcgatg acgcgaccgc
     2281 gggacgatcg acgagttcga aggggatgag ccgggaggag ctgctcgccc tccccgtgtc
     2341 agttgacctg gacacgagca accgagctct ggggctcggg cggagcaagg ggtatgagct
     2401 ggcgaagcgt ggcgagtacc cgtgcaaggt gctgcggctc ggcaatgcct atcgggtggt
     2461 gaccgcgaat ctgctggaac tgctcgggct ggccgcgtga agggtcggca gcgtagcaaa
     2521 ccattctgcg ctgagctgac acagaaacgc tggactgttg gcggacatgg acgtacggtc
     2581 cgtgttccct cgcggtggcc tggcgcccgc gagaacggga ggggcccccg gcggtgcaac
     2641 gccggaggcc ccagcaaccc cgtacggccc gtgaagtacc aacccggcgg caagggcgtg
     2701 caagcccgca gccgccagac gaggagctgc tccatggaac atgcgggagc cgagcactat
     2761 tccgactcca acacgccttc gtggccgccg gtcgctgtcc ccggccagcc agttgacggc
     2821 acggcatcgc cttcgccgaa ggcacctgcc agcccagttg aggcgccgac cgcgtcgccc
     2881 gactccgagg gcgcggagct cttggtcggc ctgcgggcgc agatcaagcg gtacgtggca
     2941 atgccgggtg aggaggctct caccgcggtc acgctgtgga tcgcggctac gcatttgcag
     3001 cgggcgtggc agcatgcgcc gcgtctggcg atcgtggctc cggagaagcg gtgcggcaag
     3061 tcacggctgc tggacgtggt gaccgagacc gtccgcaacc cgctgatcac ggtcaacgcc
     3121 agcgcggcgg ctatcttccg ctcgatcgac gacgaggacc cgccggctct cctggtcgac
     3181 gaggccgaca ccctcttcag caccgtcaag gcggcggaga agaacgagga ggtgcgcggc
     3241 ctgatcaacg ccggccacca gcgcaaccgg cccacgctgc gggtgaccgg gcccgagcac
     3301 aagcccaccg cgttccccac cttcgccatg gcggcgctcg ccgggatcgg tgatctgccg
     3361 gacacggtga tggaccggtc ggtggtcatc cggatgcggc gccgcgcgga cggcgaggag
     3421 gtggcgcact tccgcaccca ccgcgacacc cctgccctgc acacgatccg tgaccggctc
     3481 accgcctggc tccagccgct gtacgcccag gcgttggaga tggagccggc catgccggtc
     3541 gaggaccgcg cggccgacac ctgggaacct ctggtggtca tcgctgacct cgccgggggc
     3601 gagtggcccg cactcgcccg caccgcctgc cgcgtcatga ccgactacga ggccgggcag
     3661 gacgaggaag gcggcctgcg cacccgcctc ctggtcggca tccgccgggc cttcgctgcc
     3721 gagaacgacc cggcggtcct gggcacgaag cgcctgctgg aagccctcaa cgcggacaag
     3781 gaggcgccgt gggccgagta cggccccaac gggctgaccc cgcgtggcct ccaactgctg
     3841 ctgaagccct acggcatcag ctcggccaac cgccgcttcc ccgacggcac ccaggccaag
     3901 ggcttcgccc gcaaccaatt cctcgacact tgggcgcgct actgccctga accggctccg
     3961 gcggccgagc ccgcacagcc gtcggccgag ccccttcccg gctccgcggc ctgacccgcg
     4021 ccgactcgtc gcactcgtcc ccgcgcaggt cagcgcgggg acgagtgaac ggcccgcaac
     4081 gagtcatctc gacatcgcca gcccactcgt acctgctctg accaggcatg cgacgagtgg
     4141 tacgagacac cacacctcac ggcggccaca cctcgccctc ccctgccccg aggccgccgc
     4201 ccccaagccc acttggagta ccccgcttgt ctgcccgcat caccgccacc gccgcgattc
     4261 gcgtcggcat cgccctgctc gccattttcg ccttcgccct gtcctacgac gccctgcgcc
     4321 agatggccgt cgccatccac atccgcgggc ttctcaccta tgtctttccg cttgtgatcg
     4381 acgggttcat cgccatcggc gtgggagccc tcgtgatgct gcgcgccgcc tcgacatggt
     4441 cccgcgtgta cgtatggaca ctcgtcggcg ccgcaaccgt gacgagtatc tgggccaacg
     4501 ccctgcacgc cgtccgcctc aaccagcaga cccgccaggg cgatggcctc cgcctcgacg
     4561 acttcacagt cggcggcttg tccgccatcg ctccgctcgc cttggccggc gcggtccatc
     4621 tctccatcgt cgtccaccgc cagcccactg ctcgcggccc cgccgatgtg gcgcggggtg
     4681 ccgccgacgt ggcgccggat accgccgaag tggctgaggg cccgcaatcc tccgtcgaac
     4741 cgcaggatca cgagcccagc catatctctc ccgaacggct cgccctcgcg cgcaccgcgc
     4801 cactgggacg caacgggcgt gcttcccgcc gccacatcga agccaccttc cgcagcaggg
     4861 acttgaccat cggaaggacg gaggcggaca agctcaagga catcctgcag gccgaactcg
     4921 acgaagccgt ttccccgcag cagagggagc ccgaaacggc ctccgccagc gccgtctgac
     4981 ctcttcgctg gtgccgatcg ccccgccgcc ctaccgggct cgccctgtat ccccgtgcag
     5041 ccgagcatgg gggcacaggg gcggcgcacg gcgaagcatc cgaccccaaa caaccttcgg
     5101 agaccgcccc atgcacgacc cgtaccacga actcccgatc tccgagcagg agatggccac
     5161 cggcctgaac agcgcagcaa ggtatcccgt tggaccgtcc aagggccggt ccaacggggg
     5221 tccctccgcc ccaggggtgg cggaggggct cgggcaccag gaggtgcccg aggaggacaa
     5281 gctcgtcgag acccccgccg ttccgttgcc gcgagccacc gatgctgccg cgctgcaccg
     5341 cgtcgcccgc cgccgtcagc acgaacccgt ccagcgcaaa gagcgcgtcg acgtgcgcta
     5401 cagcgccgaa gagaagaccg cgatcctcgc caaggcgcgg tccctgaaca tcgccggcgc
     5461 ccactacgtc ggcgccgtcg tcatggccca cctccacggc gacctcgcgc tgtccggcca
     5521 gcgcacccca ctggacgact acatcgacga actgaccgcc ctgcgccgcg aggtcgccag
     5581 gatcggccac aacatcaatc agatcgccaa gaagctccac tccggcggcc atccacaccc
     5641 tggggacagc gccatgctgg cccaggttga acccgccttg gacgcagtag gcgccaccgt
     5701 ccgccacatc gcgtccgccg cgaaccaggc cgtcgccaag aagcgcgctc gatgatcgcg
     5761 aagatcagcg gaggcaagga cacagccggt ctgatccggt acctgttcga caccaagaag
     5821 gctaaggacc acaccgaccc ccacctggtc gcctcatggg acggcttcgc ccccgacccc
     5881 ggccgcaccg acgacttcga cgccacgaag aggctcctcg tggccgacct cgacctgcac
     5941 gtcaaacagg ccaggcgtct cggccgcacc cccgagaagc acacgtggca ctgctcgatc
     6001 cgagccgccg agagcgaccg ccacctcagc gacgaggagt gggccgacat cgcccgccgc
     6061 gtcgtcgccg ccaccggcat cgcacccgac ggagatccgg acggctgccg atgggtcgca
     6121 gtccgccatg cccccgacca catccacatt gccgccacca aggtccgcgc cgacctgcgt
     6181 acggcccgcc actggaacga ctacctcacc gccgatcgcg aactcgccgc catcgagaag
     6241 gaatacgacc tcttccaagt catccgcggt gaccgcaccg ccgccgcacg ccccacccgc
     6301 gccgaacagg agaaggcccg ccgcgccggc cacgacacga ccgcccgcga acgcctgcgc
     6361 gccaccgtcc gtactgctgt ggccgccgcc tccaccatcg aggagttcgt cagcctgctc
     6421 agccacctcg acggcgtgct cgtcgaggtc gtgcacttcc cctcagggga cgtacgcgga
     6481 tacaaggtcg ccgtcgccga cgacgcccaa ggtcccattt ggtactccgg ctccaaactc
     6541 gccccggacc tgtctctccc caagatccaa gaacgcctgg cggccatggg gccgcagccc
     6601 attgaccagt cgggtaggcg caggcccaac ccctggtacc aggcgacagc cgccgccgaa
     6661 cgcattgccc accacctgga tcaacctgac gacggagcct ctcaggccca tctggccgct
     6721 ttcggtgaag ccctcgacgc cgttgtcctt gtcacgcccc aagccgtgcg acctcaactc
     6781 cgagaagcag caaccgcgtt cgagcgcgcc acccgctccc gcatccacgc cgaacaccac
     6841 cacgcccggg ccctgcgcgg cgccgtacga gcaatgctcc gcgaacctgc gcccaaagac
     6901 ggagccgtcc tggcgatgtt cctcgacgcc gcggtcctcg tcgtcatcgc cgccgctcgc
     6961 tggcaccagc tccaccatca cgatcagcaa gtcgctgccg cgcgcgagac gctgctccat
     7021 ctccaagccg cctacggcca ggccgcagcc gcccccttgg ccgctctcgc gcaacgccga
     7081 ccgccccagc agaccgtgga tcggcacgtt cggcacctgc gccaggctgt gcccaaccat
     7141 gccgagcaga tcgtcgaaga ccccgccttc ggcgctctca ccgctgccct cgccgaggcc
     7201 gaggcagtgg gccacgatcc gcagcagctc ctccaacagg ctgccgatca acgcgccctt
     7261 gacgatgccg actctcccgc acgagtcctg acttggcgta ttcaacgcct cggcgcacgg
     7321 ccagccccca gcgcacgagc ccgtgcagcg caggctcgca gccgagcaca gagcccccac
     7381 gctccggtac acgtggcagc cacccccaca accttgctgc ctccgcggac acggcggcgc
     7441 tgacaacatc ccgcgaacag cctgggcttg acagtgctct gtgacgcgaa accagtcgac
     7501 ggcatgcccc tgacatgtgg ggagcgacaa gctcagcccg gggcggacgt agcacaggtt
     7561 cccgctgcgc cataaatagg cgaggcggtc agctggatcg tgggaccatg aatggggagc
     7621 aagaacgacg agggggcggg gatgacgatc aagcgtggcc gaaagggtga gctggggctc
     7681 gaggtgctgc cgctggttca tatggccttg ccggagccgg atgggcagac cctccttcgg
     7741 gatcggcatc cagaaactat ggctgctatt gggcatgcac tccgagcctc gctggacaat
     7801 atctctcgat tgcagggaca gcaggcccag tacgccttcg aagccgtggt tgtcgccctc
     7861 ggcggtgttc gcttgatcaa gacggaagac tccggctctt actacttcga tgacgccgac
     7921 ggtgagctcc gaccccccga ttttcggatt attctccgcg acggaaccgt gcttcttgtc
     7981 gaggtgaagc tcgtgccacc tggcaaggag aagaaagtca aagtgcgagc caaggacatg
     8041 gaggcgacgg aggcatacgc ccgtgccacc ggcgggcgct tgctgtacgc gcactattgg
     8101 agtggaccga atctatggac gctggttccc ccatccgcct tccagcgaga cgttgggcaa
     8161 caacgactta cagtgtctgc cgccatgatg gcgaacgaga tgggcatcct cggtgacgct
     8221 tttctgggcg gaaagccacc cttgaccgta tctgtattga tggatacagg catggaaaag
     8281 tcggtcgaag ccgaggatga gagcgatcag cgactcatga caacggctgg ggtggagctg
     8341 tcgagcgccg gaaaggtgat caaggatccg gcggaactga aactggcgtg gtttctggcg
     8401 tggcacagcg gttggatacc gacacagagg gcgcagttcg acagtctcgg ccgagtcgca
     8461 aggatcaact acgacttcgc tccggacgtc gacaaagacc aaatgcggga gattgccaaa
     8521 caggggtttg ccttcttcgg agcgctcagc accctctaca cggcgcggtt ccggcgagct
     8581 acaaccacag atgggggcga tatcagggca ctgagcgagg agcctcggcc tgccctcatg
     8641 gcccaactgg tacccgagga ttattgggag caagaccgaa ttctcgggct ttggaaattc
     8701 aacctcaaac cgcagtaaag aaatctgtta aaccaccgcc tgttctgcac gagggcaccc
     8761 gggtccgtac gctcatcacg ccctccccgg aaggatttta cttccaggac cggagggctg
     8821 ttcgaggctt ccccggatca cgctgtcgct ggctcgcaga gccgccgcca gttctcgttg
     8881 cagctcgtcc gggagtatcc ctgcgtcgag ggcgcaggtg cgcaccagcg cgcgacagtc
     8941 ctgcacttgc cgggccgtgg cgatctcggt gaacagaggg tgagccaagt tctcgcgggc
     9001 tgcgtagccg tcctcggcgt ccgtcgtcct gcggtggagg tcctcgacga tgcggtgcgc
     9061 ggcgagtgcc tcggcggacc cgatcgcgtc gaggacggtg agtccgaggc ggatgtcgaa
     9121 cacggtcatc ccgggttcgg ccttccgtcc ggagtaggcc gtcaccaggg cggccaggtg
     9181 gccgtcgatc gactgcccgg cgtcgcggcg gcacagaacg gtcaggcacg ccgtgacggc
     9241 ttgttcccac gggtcgccgg gcatcgtgtc ggcgaggaga ccagccgccc ctgccgtgtc
     9301 gttcgcaacg agggcggcga gtacggcgac ctgccgaccg tcgagcatcc gctggccgat
     9361 gccatggtgg gcttcgatgt gcacaagcgc ctcggcccag cgcccctcgg tggtgagggt
     9421 gcgcgtgccg tcagcgagga ggacgcgcca cagccacgcg cgaacttcct gacggtcttc
     9481 gctggccgct gtgaggtccg cagggacgtt gacgccctcg aaccgggcgg ctgtgcccgt
     9541 ctcgacggcc ttgtacaggt cgaggagtcg ctggcgcccc tcatcggcgt ggccggcgcg
     9601 gatctggagg cgggcgaggt tgacgaccgg ttccagtcct cggatcgcgc tcatgccggg
     9661 cagggggcag gcgtggaggt aggcggcggc gtgctgatga cacatctcgc gggcgaggtc
     9721 ggggagggca aggtcggagg cgatgagcgc ggcctggttg tagacggccg atgcgagacc
     9781 ctggtcggcc ttcttcaccg cggtgtcggc caggtcgacg agtgcgcgta cgcgttcagg
     9841 caggggcaga taggcggggc ggaatcgggc gacgagcggg aagcgctggg ctgtgaggcc
     9901 gtgcgggtcc atgaatcccc cgggtcgaga gtgaggactg ctgaggcggc ggtgcccacc
     9961 agtcgtgtgc cgacgggcac cgtccgctag gggtggggcg tcatcgccag tcgacgacga
    10021 tgcggttcag cggggtgtcg agggcgaagc gaccggggcg ctgctcgatc tcgggggcgt
    10081 caaggggctg gatctcgaac gtggcctcac ggtcgcggta gtcgcgatcc caggtgcgga
    10141 tggcgtcggc gaccctcgcg accagttcgt cactgccggg gccgtggccg atgacgccga
    10201 actcccagag cttgtcgccc tcgggggtct tctccttcga caggcgccgg gcgaggtagg
    10261 tgacggcgcc cttgtcgacg actgcggtcg acgaggggta ggggtcctcg gtgagcaggg
    10321 tgcccttggc gctctggggg aacagcatcc ggacaaggcc ggaggggagg gagcaggtga
    10381 caaacagttc catccactcc ggtgactcca tggcgcggac cgtcatgccc gtccactcct
    10441 cggtgcgcgg ctggtcaagc acgcctgcga gggcatctgc gtcgatgctg agcccggcgg
    10501 gggcctggag tcgtacggtg ccatccgtgc tgagcgggat cactcggcgg tcgtcgtcgg
    10561 cgatgccccg ccgaagcggc atgaaggtgt tcatctcact gccgagggac acccaccggc
    10621 cgtcacgctg ctcgtaggcg atggagcggg acaccgtgcc cttgaggcgt tggggcacga
    10681 ggagtcggcc gccgggggcg agctgctgca gccaggcgtg cggtacgccg tgcgcgccga
    10741 cggtggcgat gatccggtcg tacggcgctg tttcggcgta gccgagtgcc ccgtcgcggg
    10801 tcacggcctc ggcgttggtg actccggcgg cggcgagatg cgtgcgggcg ccttccacga
    10861 ggtcgtcgtc gacgtcgagg gtggtcacgt gtccgttctc gccgaccagg tgggcgagga
    10921 gaccggcgtt gtatccggtg ccggcgccga gttcgaggat gcgttcgccg ggctgggctt
    10981 cgagctggtc cagcatgagg gcgacgacgc cgggctggga ggcgcaggag atggacgtgc
    11041 cgtcggtgtc gtacttgatg tgcaccggtg cgttggcgta ggcgtcttcg agtgacgcct
    11101 cgggcacgaa cacgtggcgg ggcacggtcc gcagcgcggt ctcgacggcg gacgtgcggg
    11161 cgtgtccgtc cgcgcggagc tggtcgacca gggcgttgcg gaggcgctcg gcgtccgccg
    11221 tgggggtggt gatcgtgtcg gtgttcaccg cgctgacgct atcgatgtcg gccgttgcct
    11281 cggtgggcga tgcggtgtgg tcactcgttc ccatgactac ctctcgtgcg atgtgggaca
    11341 gggcgctctg gtcgttccgg aggagaccgg cgcggttggc gtggaagatc acgtggtggg
    11401 cgatgacggc tcgcaggccg cgggtgaggg tgccgcgggc tgcgaggtcg gcgagcgtgg
    11461 cgccggtccg ctcgaaggcg gtcacccatt ccttgtgcgc gtggagtggg ctgcccgggt
    11521 ggcagaggtt gtgggcgtcg gcggtcatga gcttgcgcat gggcggggcc agttcggcgg
    11581 ctcgttcggg tggtggtgga ttggtggctg gtcgaagggc tgcgactttc gcccatacgt
    11641 cgccctgttc gaaccagtcg agtccggcgc cgcgcatcag ggcgctcgcc agcaggacgg
    11701 cggtttcccg gcgtcccagg tgcatcgggc tcggctggta ggtgagcagg tggcgggagt
    11761 cgctgtggaa cagttcgtgg gctgcggcca tggcctccgt gccgccgaac gcgtcggtct
    11821 cgggctcgta gacgcagggc aggcacgaca tggccacgcc gtcgtcgatg aggtcgctca
    11881 ggagagactc gatggccggg gagggcttgt ccgcgaggta acgcagcggc cagggctgct
    11941 tgttcatgaa ccaccagccg gtgagctgcc cgtcggcctc ggcctcgatc agagcggggc
    12001 cgaggcgttc ggcgatggtg tgccgggcag tctcgcggtc gccgaaggtg atgttgtgct
    12061 gctgccagcg gtcgggaggc atagaggtcc ttcggtcggt ggatcaagcg atgaggaggc
    12121 atgcgtccca ggcggactgg ggtggtgcgg cggtgctggg cgcgaggagg gccagggcta
    12181 tgccggcggc gccgtcgagg aggccggggc cgccttcctt gtcctgaatg agcgccgtgg
    12241 ccatgagttc ggggtcagtg cttggtggga tgaccgcagc caggagggcc gggatcgcgg
    12301 ctcggagttt gtctgcggtt gaggggtggg cgtcgtcggc cgtacgcgca gcggtgtggg
    12361 cgaggccggc ggacccgtgg cagaggccgt tgtccgtcgt ggccttcagc tgctcgggat
    12421 cggtgagggc cgccacgagc gcgttctccg cgtcgatctg gcggctggcg tcgccgaggg
    12481 ccagcgcggc aagttgctgc gcgcgagcga ggccggcggt gccgtagcac caggacggcc
    12541 gccggggcgc ggacggcgcg agacgccccc tgcgcagctc gccttgagtg atccagtacg
    12601 gccagtccgg tccgccatcg gccttctgtt tccagcggtc cagccaggcc aggatggtgc
    12661 gtactgctgc atggtgcccg tcggtgacgg agccgttccg agcggcgagg gccaggagcg
    12721 cgagcacgcc gccgatgccg tgtgccatac cggtgttggc gtgtccgccg gggaatcggt
    12781 cgtccgggct gcccgagggc ccggtctccg cccaccagcc cggcagggtc tcgccgtgat
    12841 gggtgatcgg ttcggtgagg cgcacgcagt agtcgaggac ggcgcgcatc gtggagctgc
    12901 cggggtctcg gcgcagtagg taggcgccgt atccggtgag gccccggatg gtgtcgaact
    12961 cggcgagctg cggcaggcgt ccggcgtcga tgcggcggtg tgcggtgtcg agacggcgtc
    13021 cgacgtcgac tgcgatctgc ctgtccatcg cgtcgagggc gcgctggtag gagccgggga
    13081 ggtggtcggc ggcgcaggtc agggcgtggg cgaaggcggg cactccgtag aacgggtggc
    13141 tgtccgggcc gctggtgagc ggctgccggg aggcggcggc gagccagtcg tgggcgcggt
    13201 accacgggcc gtggccgttc gcggccagct cgatgtgcag gagcgcgatt ccgggcgggc
    13261 cgtaagcaag gtgctgccgg tccgaggtca gcgtcctgga ggcgaggcgc acggtgtcgg
    13321 ggtcggcgag ccgggcggcg atggcgtgga ccaagccgag cgcggggtgg gcggtcacga
    13381 ggccctccca cgggtgcggg cggtccaggc cagggcggcg gcgcgcgcca agtagaggca
    13441 cacctcttcc tccgggaagt tcactgcgac gtggcgcacg aagtggacgt ggagcaggga
    13501 ggtcaggacg tcgtcgacgg cgatgccctc ggtgtccggg ccaggcaagt gcggccggta
    13561 cgtggtgagc gccgtatccc ggtcagccca tcccgacacg atggcgtccc cgcccgggac
    13621 atggcgcatc gccgcccagt tgtcggacgg gtcggcgagc cgtacggcgg cggtgaactg
    13681 cgggcgcgga acgggagcgg gggttttcgg agggacgtgg tcgatcagcc accgcatccc
    13741 ggctgcggtg ctgccgagga acgcggaggc gatggcgacg gtgtgggccg ccatcagcgt
    13801 gcgctgaccg gggcgctgtg gctgcgcgag ctgggccagg atggcgcgcg agtccgcccg
    13861 gaagacctcc tcggccgcct cccaggcggt gccggagccc cagcggccca tctcccggta
    13921 ggaggtggga tagcgcaggt cagccagcag gccgatgctt cgtacctcgt cggcccaagc
    13981 gctcaccgtt cgggccgtgc cagcaaaggc ttccgggtcg gggagggcga tgcgtacgcg
    14041 gaggtgctgg tccgggtcgc ggaagcggat gaaccaccat ggcgggttac cgagttgttc
    14101 gagaaggccg ggcaagtgcc gggatagcaa gacgtcttgg cggcgggggt cgcagtacag
    14161 ggcggccaga agaactgagg acgcggcagg cgtctgcatc tgggtcgccg acaggacgcg
    14221 ggcccggctc ggggtgggca gaggcggcca cgtcggcggt cgggtcgcct tgaggggaac
    14281 tacgatctcg tgggctcgcc cgccgcacca gccgtacgcc tctggttccg gggcttcgac
    14341 cagcacagtc aggcgcgtgc ggtcgaggtg tctgcgcagg agcgcacggt ggccggcctc
    14401 gtcgaggtcg aggaagaggc gccggtcatc ctcaacgagg taaacgcggc gcggcagcct
    14461 ccgccgggcg cgccaggcag cgaacgcggc gtcccactcg accagagagc gggcatggca
    14521 gggcagttcg gaggcttcca gccgccaccg cgccggggtc agcacgatgc ggccgtaccg
    14581 cagacgcgga aggaacggca tcgccgcggc ggcgccccag tcgaagacag tgacctgcgc
    14641 gcactgggcg cgggacagtt cggtgaggaa ccgcaccagc ggcggggtgt gggtgtggag
    14701 gttcagcgcg tgcatcccaa tggcctcaac gcggtggcct cgctcgggga cggcgaggta
    14761 catacggcgg ccgtcgcacc ccaccgccaa gtcctccgag gtgaggacgg tgtcctgcgg
    14821 ggcacggtgc tcctgaaggc tgatcacggt gggcaggacc tgtggggagc gggtgacgtg
    14881 ggcgctctcg gggagcaggg gcgggaagga gagctgcgcg ggcatggtgt tgccgtctgc
    14941 ggccgggagg tcagcaagct cggcgaccag ggcctcccgg tcagcaaggg ccagcacact
    15001 gaggaatcgg cccgtggaga cgccggcgcc acgggacacg ctcatgacct ccagccggaa
    15061 ccgcccgcgc tgcaactcct ccaggctggc cgcatgcact cgcaccccga tctccaggtg
    15121 cggcggcagc cgaggctcgt cgggccctac gtccagagcc tcaatctgtt gatccgtgag
    15181 gatcacttcg tcacggccgt cgagcacagc ggcctgagcc agccctacga gggcgtcatc
    15241 ccgagcggag acacggggcc tgcgtgcgcc ggccggagcg cctgggtagc cgtcgggata
    15301 gccagtgccg ctgtccgcga cgacctccgc gagcggcacc atcgtgccga tgccgtaccg
    15361 ctcgtagaac cgctggtggt actcgttcca cgcggcggtc ccgtacgggc ggatgctcaa
    15421 gtgggtcagg atgagagcgg cgcgctcgat ctctcgggcg accgtttccg gcagaacgat
    15481 ctgcgcgtcg aggcggaggt cgagcgcgag ggggtggcga cgcaggccgg gggcgaggtc
    15541 tcgcatctgc gccgcgactc tgtcccggcc gccgtgcgta gtgcacttct ccaaacccgc
    15601 ccggatcgcg tggagttcgc gtacggtctc cgcgaccggg gccaggctcc cggcgtcgat
    15661 cgcgtcgagt tggcccacca gatacccgag ggcgtcggtc tcggtgctcg gagcgtgcag
    15721 gcccgtgatc agcacccgcc gccggatcag ctccgccagc aggtgacgcg ccttctcggg
    15781 accggcctca gggaactccg cctggagctt gtccacgagg gtgccgaacc ggatcggcgc
    15841 ccgggtcccg gcaaggactg cgcgcaccgg tccggtcagg gccagagacg cctcgaccgc
    15901 gcgagtccgg tcgtcttgga cgtcgggctg gaacggcacg atgagccggt ctccccggta
    15961 cgtcacggtg ttgttggcga cgacgggcag ccgttcgagg aggtccgggc atgactccaa
    16021 ccacgcgact acggcagcca gccactctgc ccccgcgcgg ccgacggcca cgtgttcctc
    16081 gccccagccg gcccgcgcct gcgggccgaa ctccgcggtg gccacgccgg cgaacaggcc
    16141 gaagggcgtg gcccggtgct gggcccgcag caggtagcgg gctacggaca gcgccgcgcg
    16201 ctgcacatcg cggcgggcgg gatgctcggc cgtgcacagg gcccgtacct gcgcggccag
    16261 gaccgggctg gagtgctgga gtgcctcggc gacgtccttg ttcgcccaga ccgcgcgtag
    16321 ccacgccaca agggcggacg aaccactggg cgagcggtca tcgaggtcag ggcatggagg
    16381 aaatggcagc gagggccggg ccacggcgcg cacgagagca gtggaaccgg tgcggaacgc
    16441 tgcgggcgga gcaaccacca agtacctccg taggcgaggg ggccgggcgg ctggtgccgt
    16501 cgcgtggaga cgcggcggca ccagactggg gtgatctggg ggccgggtca ggcgacgttg
    16561 gtggtgcagg cgccgcaggt ggacccgcag ttgtcgtcgg tcaggttgac caggcccgcc
    16621 gggtcggcga tctcgacgag ggatacgtcc aggtcgaagc cgtccgatgc cccagggatc
    16681 tgcgggcgta cttcggtgcg gctgggaact acggtgctgc gcgtcatgct tcaactcctc
    16741 ttaatcgttg gggtgttact gggctggagc gcccaccagg tgccgctgag ggagcgttgc
    16801 cactcggctg ctccccggac ggctcctggc cgcccggcat gtggggacgt gctccgcgta
    16861 ggaagtcctc gcggggcgcc tgactcaggc cgggaagtca tgtaccggga gtctgatcaa
    16921 gcggatgccg gtcgccgctc catgaagtag gcgagcgcct gggccttgag gcgatcgagg
    16981 cacggctcgc aggcgtagaa gggcgcgtgc tgcccgtccc actgcaccgg gccgagccac
    17041 atcaccagga ctccggtacg tccgcagccg agccagcaat caccggtgat ccacggccac
    17101 tccatggagg gacgtcccct ttctcagctg gtcgggatgg tcgatctggc ggcctgacag
    17161 ttgggagcac aggcccagag ctggaacggc aggccccggt ggcgtatctc gcccagccgt
    17221 cgaccgctcg ctcccagcgg ccgagcacag agggcgcagt ccatggccat ctgctggcgg
    17281 ggccggagcc gggcgagatc cggaaggggc gagggtgccg tggccgggat actcactcgc
    17341 cacccccggt gcggagttcc gcccagacct ctttgcccca ggggcgtctg cccgagccat
    17401 gcaggtcgta gccccagcgg tcggcgacag catcgacgag aagcagccca cgccccgact
    17461 cgtcgtcgtc acccgcctgg ccgagtatgg gcagacgcgt cggttcccgg tccacgaccc
    17521 caacacgcac tcgtgtcgcg ctcggccgcc cgaccgtgag gcggatctcg ggacacggag
    17581 tgtgccgggc ggcgttcgcg atcagctccg tgacgatcag cgcggcacgg tcggcgaggc
    17641 catcgatgtg ccacacaccg aggacggctc ggacgaggtc gcggccgatc tcggccgtgg
    17701 acggctcgca cgggaaggtc tggctgtacg tggggtggcc gacggagagg gcctcaactg
    17761 gtgttcttag actcgtcatt ggggtggagc cttcgtgtcg tctcggcgcc cggcccaccc
    17821 ccgcggggga acctcagggg cgggccgggc cgtcaacagc cgcccgcacg gtggggcgcg
    17881 gcgggcgacc agcacccaga caactccctt tccccgcagg ctggttagga cgttcaggca
    17941 ctcagccgac ggacctgcct aggacgtttt gacctctcct ttacctggcg ggtggggatc
    18001 gcgcggacta ccgtgcccgc atggacacca cccgcaacac cgttcttgag gcgtggatga
    18061 ccgaacacgg ctacagctcc aacagcctcg ccgaggccgt gaacagcgcc attgaacggt
    18121 tgaccgggcg ccctggagga ctcgacggct catcggtccg ggcatggaaa gcgggccggg
    18181 tcacgtggcc aaagtcagcc gcccgcaagg cacttgagga cgtcaccgga ctacccgccg
    18241 tcgctttagg gttcgtgcca cggagccggc cttcgtccac cccggcccca ccgcagcagg
    18301 aggaccccga catgaagcgc cgcaccctcg tcggcagcat cgcggcggct gccgcagcag
    18361 cagccgcacc cggcaccaca tcgccgcgcc gtatcggcat gagcgacgtc aaccgcctca
    18421 acaagcgctt cgccgagatc atcgccagcg accaccgcca cggtggacaa ctcggcatcg
    18481 aacagcgggc cgccgccctc gccgacgagg cactcaacct ccagaacgcc ggcagcgcca
    18541 cccagcgggt gcgcagcaac ctctacgcct ccgcagccgc cttccgctcc tccgcgatgt
    18601 gggccgccat cgacggccgc cgctacgaca tcgccaaggc acacatgcgc gaggcccagg
    18661 ccctcgccga gatgtccggc gaccaggcga tcaagttccg catctggagt cacgcgggca
    18721 ccatgtaccg ccacatgggc cgtccggccg acgcgttcgc cgccaacgac gtcgcccgca
    18781 acctgcacct cacacgccgc gaccctctgt tcgcctccct cggtctggcg cgccagggcg
    18841 caatccacgg cacggcacag gaccgcaccg gcacccgccg ggccttcgag caggcccagg
    18901 acgccatgct gcgagccgac cccgccgact accggccggt gtggatgctc gccttctacg
    18961 accaggccga gctggactcc ctagccctct ccgcacactt ggcgctcggc gactactcga
    19021 ccgccgagta ccacgcccac cgctgcctgt ccgccctccg cccccacatg atccgctccc
    19081 gcgcaatcac caccacccgg ctcgcacacg ctcagctcgc ccagggcgcc cccgacgccg
    19141 ccacggccac cgcgatgaag gtccccgccg aagccgccac ccagcacgcc cgggtcactc
    19201 gcatgctgca ggagttcggg gccgcactgc gcgccaccgc gccgggcacc tccaccgtgc
    19261 agacctggac cgagcacacc gccacctgga ggatggccgc atgaccacgg cgcccgccat
    19321 cgaactgcgt accttcacca ccctcgacac agcccgcggc gacctcctcg acgtgtacgc
    19381 cgacgtacgc gccccactcc tccacctgcc gaactacgcg gtcaccgcgt tcggcgaacg
    19441 cctggaccga cacggcaccg agccggggtt cacggccgtc ctcgcgtacg cggacgggta
    19501 tccggtcggc tacgcctacg gcaacaccat cgagcacggc gaccgctact ggcagcgcac
    19561 cagcccgacg ccggcggaga agtacaccgc gcatccggcc gtggctttga aggagatcgg
    19621 cgtccggcaa acctggcgga agacaggcac cgctcgccgc atccacgacg ccctcctcgc
    19681 cacacgccac gagtccttcg tcacgctcat ggtcaacccg gctgctggag acggaaaggt
    19741 ccacgcgctc tacaagtcgt gggggtacaa ggacatcggc cagagtcagc cgtcaccggc
    19801 ctcgccggtg ctcgccgtga tgatccgtac cattcgctga acagcccccg aggacgtgcc
    19861 ccacaacgtg gtgtagggga ttcgcatccc ctgtcagcac ccggcgctat cgttgaagca
    19921 ctcagctcaa ggggcaccgt tcgtgatgct gtcacgcagt gaagggggaa aggctcatga
    19981 gtcctaggcc agggggtgag gctgacaaat ttggtaaccg ctatgaaggc gcctggacga
    20041 ttcgacacgt tctctacgtg cttcttggta cgggtcattc tgtaacggtc gaggacatcg
    20101 atgagctggg cctgggagcc gagttcacct atcgccacgg cgacaccgta gaagtccatc
    20161 agttgaagcg gcagaacggc agcgcaaaca cctggacggt caaatctctc caagacaaag
    20221 ggatttggga gaacgttcgc tcgcacgtcg aagatggacg tcagttccgc ttcgtttccc
    20281 tattgcctgc cagtcccctt caagagcttg ccgatcgcgc aaggcgctca ggaaaccatg
    20341 atgatttcat caagcattgg ctaacgaaag ggctcaggga cccattcgac gacctttcat
    20401 cttccgaaat ctttgaatct tcggagatag catggaaaat cttgcgaggc ttttcgatct
    20461 catggccaga tgagcaagac attgtgagca tgaacggagc attggcacaa ctccttttgg
    20521 aaggtgcagc cggaagtcta gcggcagttg gtctagggga cttgattcag aattcccttg
    20581 gtgtcacgct tgatgccccg gcaattgatt ctcgcctggg cacttatgga ctgagtcggt
    20641 cccgactgct taacgcgagt gggattgctg aacaggttag ctcggtttct aaggggtggg
    20701 catcgaatat tgagcgagag ctccttcaac cgactattga tcgctccgag gccgaccagc
    20761 tagtagggct aatcaatggg tcgaataaac ttcttctatt gatggggcat ggtggcggcg
    20821 gaaagagtgc cgcgcttcat cacgtctacg aatctcttga cgcggattcg gtgccacttc
    20881 tagctttccg gcttgatcgt ctcgagccct tctcctctac gactgagcta ggggaaagga
    20941 ttggcgtagg tgtttctcct gtcacggcac ttgctgcagt tgctggagag cgctccagtg
    21001 ttctcatcgt ggaccagttg gacgccgtta gtctgacatc agggagaatg ccgaggaact
    21061 ttgatgccgt tgcgagtttg gtgcgcgaag cgtcagcatt tcctgcaatg acggtcgttc
    21121 tcgcttgtcg gaaatttgat gtcgagaacg actaccggat ccgcgaactt gcagatgcca
    21181 agaattgcgc gcatgtcgag gtcggggagc tttccgacgc gcaagtcaca gagtcggttc
    21241 gtgcaatggg attggatgcg aacgcgctag ctgaccacca aaagacgcta ctgcgctctc
    21301 cgctgaacct tgttctgttg aagagtatcg ccggcgacga agacgccatg gcatttcaaa
    21361 ccacgaaaaa tctcttcgac gccttctggc aacgcaagct gaccgactgt cgccagaggc
    21421 gtgattcagt tcgctttaac aaggttatct cgactcttgc tgaggccatc agtgcgaggc
    21481 agcggctctc tgtcccgatt actgctcttg atgccgatga tctggctgat gatgcgggag
    21541 tccttgtctc ggagcatgtt ctcgttcgcg atggtcagca gatcgcattc tttcatgaga
    21601 gcttcttcga ctacgccttt gctcgtggct ggatcgagcg cgatgagtca ctcgtatcgt
    21661 tcctgctggg aggagagcaa gaactcttcc ggcgggcgca agttcgtcaa gttatgaacc
    21721 atcttcgaga actcgagcca gaccgcttcg ctgtcgagac ggaggcccta cttacgagtc
    21781 ccgacatcag gtaccacatc aaagatgtgg tccttaaact tctcggatct ctgtctgacc
    21841 caacatcccg tgaatgggag atggtgacca acgtccaaga gacacaccca gccttcgagg
    21901 cacgactgtg gcgaatcctc cagacagcac cgtggtttga gcgtctcgat gcggagggtg
    21961 tcatcgaaga gtggcttgac ggggaagacg aaacagagca gggacgagcc atcgaagtga
    22021 tggcaggggc tgcgaaatca agccctgatc gtcttgctga gatccttcag aggtacaagg
    22081 ctgtagccga atacccgcag tggctacgat gggtaactcg gttctctgat atccatcaga
    22141 gtcgccctct atttgatttg ctcctcgacg ccgtgaggag cgggcaatat gtgggaatgg
    22201 aggatgaagt ctggctttct gctcatgatc tcggtaagca gcggcccgat tgggtggtcg
    22261 aactgttggc cgcacacctc gtggaccggc ctagtgccat ggccgtagat gacaaaggga
    22321 agatcgagac cctacttgac cgagattact cggtaatcca actaacgcaa ctcgcggcag
    22381 cgggagcacc agagcttttc tgtgaacgtc tcatcccgta catgttggga gtaatggcta
    22441 agacagccta cgagcacgat gacagccgcc ctcataggga tcggcatttc tcccaccgcc
    22501 acccacgaac caacattcgt gaacttgaag atgcacttct agcaggggct gctacagcgc
    22561 ttcgcgggat cgttgaaagg gacgccgcat cggctcgtcc agtcctcgaa agcctcgcgt
    22621 ttgatcctca cgacacagcg cagtggctcc tctatgaggc attgcgggcg gcaggtagtc
    22681 actacgcaga ttgggcagcc gagcttctac ttcaggggac ccaccggttt attagtggct
    22741 actatgcggc aaatgctgta tggaaaacgc gggaactcat ccagagcacg agtcagttca
    22801 tgcctgatga ggcattcgcc agtattgaag ctgcgattct cgaagttcgt tttccatggg
    22861 agtccaagcc tacgggctgg tacccgttta atctgctttc agcgatgcaa gaagatcggc
    22921 tatctgagct agggcgccgt cgactcggcg aactacgcag gaagtttgat tccgatcagc
    22981 cggcagagcc tcagggcgta acgggaggcg cgatcggcgc tcccattaat caggctgccg
    23041 ccggacgcat gagcgatgaa cagtggctgg gtgccatagc aaaacataac tcagagagaa
    23101 ccgactggcg gactcacacc ggtggcgctt acgagcaatc acatgtccta caggagcaaa
    23161 cgaagagcga tcctgagaga ttctctcggc tagctcttcg atttgatgaa agcgtccatg
    23221 ctgcttacgg tgatgcaatc ctcatgggac taggcaacgc cgatgccctt gctgaccctg
    23281 cgccggtgtt tgaagccgtc cgacacatcg cttccctcgg acacgaggca aacaatcggt
    23341 ggctgggatc tgccatccga aagtatctca agacagttcc tcaagatatc gttcagctta
    23401 ttattgaccg cgcgaccggt gctagtgacc cagttgatgg cagcttgact gtccaaaccg
    23461 ccaatcaaga gcacactcag ggacgagacc tgtatacgtc ggggattaat tcttcgcgag
    23521 gaagtgcggc agagattctg ggtgacctcc ttatctacga cgcggatggc tctcgaacag
    23581 cgttggttct cccagtgctc gatgcaatgg ccgaggatcc tgctgtcacc gtacgctctt
    23641 gtgtcgcgca tgtgattcat gcctctatgc gtcacgctcg tcctcaggcg ttgcaagcat
    23701 tcgctcgcct cattaatgca gacgatgaac ttctggctac acatgctgta gtgcggctta
    23761 tggctcacat tggctttgag gaccttgacg tagtgaagcc tgtgattgaa cgcatgcttc
    23821 aatcggagag atacgagacg cgacagtgtg gcgggcaatt ggctgctctg gctgcgatgc
    23881 attggagctt ggtagagatg ttggactcgg tgctctcagg cgaagacgta gccagccgta
    23941 ttggagctgc cggggcttgt gctcacgggc tgtctaatgc gaccgatacc gccgttgctc
    24001 agcgagcctt cgagcaattt atcgatgacc ctgaagacaa agtacgcggt gctattgctg
    24061 aatttgcatc ggtagttcgc ggtcaacgcc tacgtcccct gaaggtctct ctcaaagcac
    24121 taattcattc tgcctctttc gaggaggctc taccgcaact gctaattact cttgagcacg
    24181 cctctgaccg cgtcgacgac ttggcgttgg agtgcggtcg tcgattcgtt gagatccatg
    24241 gagagggctc gggagacatt cggaatcgcg cagcagcaga cgcacggcat gttggtgagc
    24301 tactagttcg ggcgtacgcg caagctacat cgactacaag ccgcgggcag gttcttgatc
    24361 tactggatca acttctgctt atcggggcct ttggtgtggc ggacttggta gaaaagtctg
    24421 agcgatagta gtgaacgggc gtgattccca caccattggc gatcagcaga gcgccgggcc
    24481 ggtcctgcgc tctcggcaac gggtgaaacg agggccacgt acggcggatg aaaagtgagc
    24541 cggattaggt ggctcgctgc gcgcttctga ccagcggaaa cagtaccgcg tggcagcgtc
    24601 gagcaccccg cggcatggat ccaatcccac tcctaaagcg ggtgtcgcag ggatcgaatc
    24661 ctgccgtcgc tacactcagc gcccggtgga gaaggccgct cgaaggggga gcggcggata
    24721 tacgcgaatc ctgtgaggca gcaggagcga acgctctggt cagcggcatg ttctgcgtga
    24781 gcgatgcgtg agcggacggt gtggcacaac ccgccgcgcg gcggatcggc actcacggcg
    24841 cacatgctct gaccaggcgg ttccggacac cgaaccagcg tccggaacca cccaacaggc
    24901 tttggccagg acttttaatc cattggttgt gggttcgagt cccacagggc ctaccgacgg
    24961 cgctcgggtc ggcttcggcc ggtccgggcg ccgactcgtt tccgggcagg cgggcgcgcg
    25021 ggtggggtca gccccggtcg ccgttgagcc acgcgagcag gcgggcgcgc tccttgtagg
    25081 agcaaggagt gtggacggcg ccggacgtga cgtaggttcc ggacccgccc cgcaggtcgt
    25141 acccgtagtc gctggggccg tactcgccgt cgcggtagcc gtccatgtcg tcggcccagt
    25201 cgaggagacc gaagtcgaac ccgaggccga gattctcgag gtaccgggcg gggtcggccg
    25261 gttccaccgg cgcgggacga gcggccgccc cggcggcgag ccggtcttcg aggcagccgt
    25321 cggagcgcac gggctggccc agccaccacc cggccaggaa cacggcgtac agagctgtgg
    25381 cggcgccgag gcggcgcggg gttgtccagg caggcatccg gggagtgtca cacgacacgg
    25441 gtccggcgcc cgcgtcggcg gacgcgcccg gccacatcac cccctaccgc caatcgccct
    25501 cgaaccacgc ccgcaggcgg gggcgttcgc ccgtgtcgtt ggtgcaggcg acggcgtagt
    25561 cggcgaacgt ctgggacaga tggacgtcgg cgcccccacg cgggccgcgg gccgggtccg
    25621 gcatcggggc ggacgggagg ggggacaccg ggtcgtaccg tgacgggtac gccgtgggcg
    25681 tcggagtggg tgtggggaac ggtacgggtt cgtactcctc ggcgatccgg tcgagggcgg
    25741 cctggtcgac gtggcattcg ggggtgacgg gctgccccag gtaccagccc gcgacgaaca
    25801 cgccgtagat cgcggcggcg gcgccgaggc ggcgcggggt gacccggcga ggagtgttca
    25861 cgggcggccc cgctccgggg cccgggcggc gccccgtcgc gcctggacag cggcctcggc
    25921 gtcgccggct cggcggtcac ggacgaaccg gcaggcggcc gagtacgcgg cgagggtgaa
    25981 ggccgcaccg gttccgggga gggcgcggag gccaacccgg tgtattccgt gcggtgttgt
    26041 gctcatgccg agggacccta gccgcagcgg tgaccgccct gtccgtggct ctgcccgtga
    26101 gccgccggcc gggaccggtg cagggcctcg atcatccagg gctggaaggg caggtgtgcg
    26161 ggcaccacct gccagtcgtt gacggtccag accaggcgcc agtaccgctc gacgagcggg
    26221 tcgtgtcccg cgtcgaactg ccgggccatc cacgcccgca gctcggggct gtcggggcgg
    26281 ccgagcgtgg cggcgaagcg ctccacgacg gcgtcgacga ccgggacgg
//
