LOCUS       NZ_CP019724            20963 bp    DNA     linear   CON 01-JUN-2024
DEFINITION  Streptomyces pactum strain ACT12 chromosome, complete genome.
ACCESSION   NZ_CP019724
VERSION     NZ_CP019724.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces pactum
  ORGANISM  Streptomyces pactum
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Streptomyces pactum ACT12 Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2017) College of Life Sciences, Northwest A&F
            Unversity, No.22 Xinong Road, YangLing, Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2016
            Assembly Method                   :: SMRT v. 2.3.0
            Assembly Name :: version 2.3.0 of the PacBio Single Molecule Real
            Time
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002005225.1-RS_2024_06_01
            Annotation Date                   :: 06/01/2024 05:58:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,315
            CDSs (total)                      :: 7,221
            Genes (coding)                    :: 6,992
            CDSs (with protein)               :: 6,992
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 229
            CDSs (without protein)            :: 229
            Pseudo Genes (ambiguous residues) :: 0 of 229
            Pseudo Genes (frameshifted)       :: 84 of 229
            Pseudo Genes (incomplete)         :: 195 of 229
            Pseudo Genes (internal stop)      :: 15 of 229
            Pseudo Genes (multiple problems)  :: 62 of 229
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:20:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3565057
            Orig. end                         :: 3586020
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019724.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Northwest A&F Unversity.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20963
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="23"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20963
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20963
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10963](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10963
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    119..132
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    766..779
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.32"
                     /tool="antismash"
     gene            complement(875..1462)
                     /locus_tag="B1H29_RS14575"
                     /old_locus_tag="B1H29_14645"
     CDS             complement(875..1462)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992418.1"
                     /locus_tag="B1H29_RS14575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14645"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_055418308.1"
                     /transl_table=11
                     /translation="MRDDDAAPDQGTVGGLVHRAVDGDEQATHDLLAHVHPLALRYCRT
                     RLSRLPGDARHFVEDLAQEVCVAVLLALPRYKDTGRPFEAFVFAIAAHKVADLQRAAMR
                     HPGSTAVPSDEMPERPDDSLGPEERALLNSDAAWAKKLLANLPENQRELLLLRIAVGLT
                     AEETGQMLGMSPGAVRVAQHRALSRLRALAEQ"
     gene            complement(1743..2354)
                     /locus_tag="B1H29_RS14580"
                     /old_locus_tag="B1H29_14650"
     CDS             complement(1743..2354)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019431595.1"
                     /locus_tag="B1H29_RS14580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14650"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003948568.1"
                     /transl_table=11
                     /translation="MTSVLVCDDSPLAREALRRAVATVPGVERVTTAANGEEVLRRWGA
                     DRSDLILMDVRMPGLGGVETVRRLLSADPGARIIMLTVAEDLDGVALAVAAGARGYLHK
                     DASRAELRATVTQALADPTWRLAPRRLRSAEMGAAPTLTAREIQVLEGMSHGRSNAEIG
                     RELFLSEDTVKTHARRLFKKLGASDRAHAVALGFRWGLVR"
     misc_feature    2525..2538
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.67"
                     /tool="antismash"
     misc_feature    complement(2596..2612)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.46"
                     /tool="antismash"
     misc_feature    2650..2665
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    complement(2694..2712)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.96"
                     /tool="antismash"
     gene            2736..3074
                     /locus_tag="B1H29_RS14585"
                     /old_locus_tag="B1H29_14655"
     CDS             2736..3074
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974205.1"
                     /locus_tag="B1H29_RS14585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14655"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_055418309.1"
                     /transl_table=11
                     /translation="MADFSRLPGPNADLWDWQLLAACRGVDSSLFFHPEGERGAARSAR
                     ENSAKEVCMRCPVRAECAAHALAVREPYGVWGGLTEDEREELMGRARNRLVAATASASA
                     GGEAAAHH"
     gene            complement(3231..4151)
                     /locus_tag="B1H29_RS14590"
                     /old_locus_tag="B1H29_14660"
     CDS             complement(3231..4151)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029852.1"
                     /locus_tag="B1H29_RS14590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14660"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_055418310.1"
                     /transl_table=11
                     /translation="MIEARHLRVLRAVASTGSFSAAGRELGCTQPAVSQQMKALEASVG
                     TPLLVRTGREMRLTQAGEALVRHAAGIIAGLTAAEEEVAAIAGLRAGRVRLVSFPSGSS
                     TLVPSALAALRAAHPGTRVFLEEAEPPKSVELLREGDCDVALAFRYEGAAGAEEWDDLV
                     VRPLLTDRLVALVPERHRLARTEPGGSVAIGELARDPWIAGCPRCRGQLVEVCEGAGFT
                     PRIDFATDDYPAVAGLVGAGLGVAVLPQLAVESVRPRGVRTVTLEPAVRREIVALTLPD
                     LAQVPAVTATLDELARAGAGQSAAR"
     misc_feature    4134..4148
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     misc_feature    complement(4144..4159)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
     misc_feature    4207..4222
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.68"
                     /tool="antismash"
     misc_feature    4214..4229
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.23"
                     /tool="antismash"
     misc_feature    complement(4217..4232)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.11"
                     /tool="antismash"
     gene            4243..4911
                     /locus_tag="B1H29_RS14595"
                     /old_locus_tag="B1H29_14665"
     CDS             4243..4911
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986401.1"
                     /locus_tag="B1H29_RS14595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14665"
                     /product="MOSC domain-containing protein"
                     /protein_id="WP_107095271.1"
                     /transl_table=11
                     /translation="MKLLSVNVGRARAVPYTDHPEGVTGIDKRPADGTVRVTAPGPKGA
                     GASGLAGDTVCDTRHHGGADQAVYAVAREDLDDWERELGRPLPNGAFGENLTTTGLDVS
                     GTLIGERWRIGPDLVLEVTSGRIPCRTFQGHLGERRWVRRFTEKGAPGAYLRVIEPGAI
                     RAGDAVEIVHRPAHEVTVALQFRAVTTERELLPLLLAAGEALHPEALAAARKYVEAYGA
                     "
     gene            4953..5726
                     /locus_tag="B1H29_RS14600"
                     /old_locus_tag="B1H29_14670"
     CDS             4953..5726
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (2-160). E-value: 2.6e-12. Score:
                     39.0. Matches aSDomain:
                     nrpspksdomains_B1H29_RS14600_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132155.1"
                     /locus_tag="B1H29_RS14600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14670"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_055418312.1"
                     /transl_table=11
                     /translation="MTTALITGSTAGIGAAFARRLAAGGHDLVLVARDTKRLREQATEL
                     HDRHGIEAEVLTADLATDTGIEAVAARLGERRSPVDLLINNAGFGNKGRFLDVSMADEL
                     TMLKVHCEAVLRLTSAATAAMRERGRGGVVNVASVAAFVPRGTYGASKAWVVQFTQGVA
                     KDLAGSGVRLMALCPGFVRTEFHERAGMGTDNIPNWMWLDADKLVTAALDDLARGKSLS
                     IPDPRYKALMGAAKLVPRGMLGGITSRTGRKYGPR"
     aSDomain        4959..5432
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B1H29_RS14600_PKS_KR.1"
                     /evalue="2.60E-12"
                     /label="B1H29_RS14600_PKS_KR.1"
                     /locus_tag="B1H29_RS14600"
                     /protein_end="160"
                     /protein_start="2"
                     /score="39.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALITGSTAGIGAAFARRLAAGGHDLVLVARDTKRLREQATELHD
                     RHGIEAEVLTADLATDTGIEAVAARLGERRSPVDLLINNAGFGNKGRFLDVSMADELTM
                     LKVHCEAVLRLTSAATAAMRERGRGGVVNVASVAAFVPRGTYGASKAWVVQFTQ"
     CDS_motif       4965..5051
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B1H29_RS14600_0001"
                     /evalue="3.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="B1H29_RS14600"
                     /protein_end="33"
                     /protein_start="4"
                     /score="16.5"
                     /tool="antismash"
                     /translation="LITGSTAGIGAAFARRLAAGGHDLVLVAR"
     gene            complement(6970..7863)
                     /locus_tag="B1H29_RS14605"
                     /old_locus_tag="B1H29_14675"
     CDS             complement(6970..7863)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192412.1"
                     /locus_tag="B1H29_RS14605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14675"
                     /product="DUF1963 domain-containing protein"
                     /protein_id="WP_055418313.1"
                     /transl_table=11
                     /translation="MDHQGEFRRAALELGIPDDEVSRFTQHLRLSIGLSGVGGGSPVGQ
                     FGGLPRLPVGMKWPSAGDSPLPLLFSVDCGALPRVDGFDLPEDGTLLFFVDQEMDHEDS
                     SGRYARVVYVPDGTETAVAEAPGSVGVREQLDVSAELRAELPLWLQEGDEDDDWHEYWE
                     DLDWEDMSPFQQQLVRYMERDLPHLNKLRDLAHDLWPSGAGVVIGGYADDEVINSIAEQ
                     TLAGREKAGEIPAVPIAKWYSHLEKEKHRLTSEWISLASEARVYEEYYTSFVIRHDDLA
                     AARVDKALAVTNFDAP"
     misc_feature    complement(7873..7884)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            complement(7949..8209)
                     /locus_tag="B1H29_RS39325"
     CDS             complement(7949..8209)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039384.3"
                     /locus_tag="B1H29_RS39325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6228 family protein"
                     /protein_id="WP_234393015.1"
                     /transl_table=11
                     /translation="MFSAEPAEDSRGWNGARAWCSLERDLTVSAKHVEPHVQLTGGCTI
                     HSLTTGDTSKSGLITLPERACVTPPWRCAASWSRIRWDDPR"
     gene            8412..9041
                     /locus_tag="B1H29_RS14610"
     CDS             8412..9041
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B1H29_RS14610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_199832338.1"
                     /transl_table=11
                     /translation="MAPPQLAPGHRCPAVGQPATPPTDGYPPQDLEGNTSNQPPKPPAP
                     PRAGPDAQAPQPDDDAPPEPQLTAARSLVDAFPALSPDLRHIPRAMRPELTRLTARWLA
                     AGHPPTAVRTHILRGLPDDGTPVHRPGGLLRHLLRDVPPSPSPPAPADRPATSAPPHPD
                     DRPARQQPPGPRLSHRLAGTRECAGDHVQPLLFRPVADETHCPRCR"
     gene            complement(9280..9447)
                     /locus_tag="B1H29_RS38555"
     CDS             complement(9280..9447)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B1H29_RS38555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_199832339.1"
                     /transl_table=11
                     /translation="MRTGPRCPEDQKLLIEELIGLGVMRRRRDGRIDLPDVYRIAFGVG
                     RKGGVPRVAG"
     misc_feature    complement(9587..9600)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.53"
                     /tool="antismash"
     gene            10001..10963
                     /locus_tag="B1H29_RS14615"
                     /old_locus_tag="B1H29_14685"
     CDS             10001..10963
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B1H29_RS14615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B1H29_14685"
                     /product="hypothetical protein"
                     /protein_id="WP_234393016.1"
                     /sec_met_domain="T1TS (E-value: 0.0011, bitscore: 17.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDDLQPDVLRLELTELGDAFRAYQRRPEPDLAVLAELHDRKARA
                     FALWADVTDDASLWEEAVRAEAAARTTREMNANRLGIEVDGDGPVVDRLLTRGQGAHAR
                     GVLEYVRAHAPLPGAEARLAVLMLTLRAARAGTGNVTGQDLSGWLQGDAERVIQELADV
                     GWLRLPEGVDAADALDSRPEEPTQVTVPSLLPAEPRPIPFGKITRARLSGWAQKVVGDR
                     KLRKKKAGAATRLLAVYTAAHSRPDGRLGERVGERVEGAAGDGVGLDAVASFCGLRPED
                     VAEHAEVLVAAGWLADASAAGGRLRGRLGARVLPLSGLV"
     gene            11164..11406
                     /locus_tag="B1H29_RS38840"
                     /old_locus_tag="B1H29_14690"
     CDS             11164..11406
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B1H29_RS38840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B1H29_14690"
                     /product="hypothetical protein"
                     /protein_id="WP_055418316.1"
                     /transl_table=11
                     /translation="MGRLIPLGDLWDVLVDGTGAAFTDRLKRESEAAVKFYAKARTHLL
                     GKYGSDTHTDFLADHRSSGRCCWARSLPTCPRCAG"
     gene            11385..11783
                     /locus_tag="B1H29_RS38845"
                     /old_locus_tag="B1H29_14695"
     CDS             11385..11783
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B1H29_RS38845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B1H29_14695"
                     /product="hypothetical protein"
                     /protein_id="WP_055418317.1"
                     /transl_table=11
                     /translation="MPALRRLTGARLAALNHGSVRSRTVPAGDVVVRRMRDLRDDVTAP
                     PWRTAVADAGTGRTLPEVDPDAVRGLKFAEALPPRLAEATLAARLTDEEGARAALAEPV
                     RSSGEQPRRERVATPGDELRRADAHPVP"
     gene            complement(11861..13486)
                     /gene="groL"
                     /locus_tag="B1H29_RS14625"
                     /old_locus_tag="B1H29_14700"
     CDS             complement(11861..13486)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="groL"
                     /gene_functions="other (smcogs) SMCOG1299: chaperonin
                     GroEL"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384131.1"
                     /locus_tag="B1H29_RS14625"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES; misfolded
                     proteins enter the barrel where they are refolded when
                     GroES binds; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14700"
                     /product="chaperonin GroEL"
                     /protein_id="WP_055418318.1"
                     /transl_table=11
                     /translation="MAKILKFDEDARRALERGVNKLADTVKVTIGPKGRNVVIDKKFGA
                     PTITNDGVTIAREVEIEDPYENLGAQLVKEVATKTNDIAGDGTTTATVLAQALVREGLR
                     NVAAGASPALLKKGIDAAVAAVSEDLLATARPIDEKSDIAAVAALSAQDQQVGELIAEA
                     MDKVGKDGVITVEESNTFGLELDFTEGMAFDKGYLSPYFVTDQERMEAVLEDPYILINQ
                     GKISSIADLLPLLEKVIQANASKPLLIIAEDLEGEALSTLVVNKIRGTFNAVAVKAPGF
                     GDRRKAMLQDMAVLTGATVISEEVGLKLDQVGLEVLGTARRITVTKDDTTIVDGAGKRD
                     EVDGRIAQIKAEIEATDSDWDREKLQERLAKLAGGVCVIKVGAATEVELKERKHRLEDA
                     ISATRAAVEEGIVSGGGSALVHAVKVLEGNLGKTGDEATGVAVVRRAAVEPLRWIAENA
                     GLEGYVITSKVAELDKGQGFNAATGEYGDLVKAGVIDPVKVTRSALENAASIASLLLTT
                     ETLVVEKKEEEEPAAAGHGHGHAH"
     misc_feature    13499..13513
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.16"
                     /tool="antismash"
     gene            complement(13605..13913)
                     /gene="groES"
                     /locus_tag="B1H29_RS14630"
                     /old_locus_tag="B1H29_14705"
     CDS             complement(13605..13913)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="groES"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966899.1"
                     /locus_tag="B1H29_RS14630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14705"
                     /product="co-chaperone GroES"
                     /protein_id="WP_055418319.1"
                     /transl_table=11
                     /translation="MTTTSSKVAIKPLEDRIVVQPLDAEQTTASGLVIPDTAKEKPQEG
                     VVLAVGPGRFEDGNRLPLDVTVGDVVLYSKYGGTEVKYNGEEYLVLSARDVLAIVEK"
     gene            complement(14159..14878)
                     /locus_tag="B1H29_RS14635"
                     /old_locus_tag="B1H29_14710"
     CDS             complement(14159..14878)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029848.1"
                     /locus_tag="B1H29_RS14635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14710"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_055418320.1"
                     /transl_table=11
                     /translation="MRRGRFRPAGAALAAVLLTGCAQSAGPAQQPAAGEPAQGSYRGQN
                     LPPVVDHVRTTDRVVFLTFDDSAERDPHFADLVRAHRLPVTLFLTDTVAGPAYGHFARL
                     RSVGASLQNHTLDHRSLRGLPYAGQRAEICGQQTKLKSRFGVRPHLFRPPHGRYDTTTL
                     RAAADCGITAVVLWRAVLNPGGDLTYTRGNARLHPGDIVSVAPDHPTGLGLSARTERLL
                     AEIEEQGLRVGRLGDYL"
     gene            complement(14875..15744)
                     /locus_tag="B1H29_RS14640"
                     /old_locus_tag="B1H29_14715"
     CDS             complement(14875..15744)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130739.1"
                     /locus_tag="B1H29_RS14640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14715"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_055418321.1"
                     /transl_table=11
                     /translation="MRGGVAALAVAALASGCAQDASEVRGAAGRQPLQAPPARALDAYA
                     SKLRAAQAARVAAAKRWNLKKVPLTAPPPPARKPEIKAREGFEVTGQKNLPPVFTSIPT
                     KEKIVFLTIDDGAEKDPAFLRMMSELKIPYTAFLSDYLAKEDYGYFKKMQDRGVTLNNH
                     TLHHPYLPGLSYAEQKREICGMQDVIEKRYGKRPTVFRPPYGNYDRDTLRAAKACGIEY
                     APIWNEEVFADHWDYREWDREIHPGDIVLTHFRGEDDWGGTMRDMVREFLDKVTAEGYA
                     VARLEDYL"
     misc_feature    complement(15791..15807)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.46"
                     /tool="antismash"
     misc_feature    15791..15807
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.5"
                     /tool="antismash"
     gene            15907..17082
                     /locus_tag="B1H29_RS14645"
                     /old_locus_tag="B1H29_14720"
     CDS             15907..17082
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327060.1"
                     /locus_tag="B1H29_RS14645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14720"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_055418322.1"
                     /transl_table=11
                     /translation="MNDLDALLALLTPEGRALLDEVRDTDPARELAVATRLRRAHPAEL
                     VSAALGQARLRQRAAAKFGAEDAGRMFFTPNGVEQSTRASVAAYRAGRMSVLGVTSVAD
                     LCCGIGGDAIALARAGIRVLAVDRDPATAAAARANAEALGLAELIEVREADVTEVDTSG
                     YDAVFVDPARRGGRGRVFDPEAYSPPLSWAVAAARTASRAAALKVAPGIPHEAVPDGAE
                     AEWISDGGDVKEAVLWFGTAPGTVRATLLPGPRTLLGTGLPDPGVRTPGRYLYEPDGAV
                     IRAHLVAEAAERVGGGLLDATIAYVTADELVPTPYARAYEITDRMPFNVKKLKALLRER
                     RVGVLTVKKRGSAVEPEELRRKVKPQGPNAATVFMTRVAGAPTMLIGHPVR"
     gene            complement(17947..19200)
                     /locus_tag="B1H29_RS14650"
                     /old_locus_tag="B1H29_14725"
     CDS             complement(17947..19200)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029845.1"
                     /locus_tag="B1H29_RS14650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14725"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_055418323.1"
                     /transl_table=11
                     /translation="MEPQPTEALETVFRLESPRVIAGVARLVRDVGLAEELTQDALVAA
                     LEQWPRDGVPDNPGAWLMATARRRAVDLIRRRENYARKLAEIGRDLPTEAAPPEEPAGV
                     DDIDDDLLRLVFTACHPVLSAEARIALTLRLLGGLTTPEIARAFLVPEPTVAQRIVRAK
                     RTLATKNVAFEVPYGPDRAARLGSVLEVIYLIFNEGYAATAGDDWLRPALCEDALRLAR
                     VLSALMPKEPEVHGLTALLELQASRTAARTGPDGAPVLLKDQNRSRWNRMLIARGITAL
                     GRAHAGSGSGAPGPYALQAAIAACHATAYTYEQTDWPRIATLYGLLAARAPSPVVELNR
                     AVAVSMAEGPARALALVDTLAAEPALSDYHLLPSVRGDLLLRLGRTAQARTEFERAAAL
                     ARNERERELLARRARECG"
     gene            complement(19245..19601)
                     /locus_tag="B1H29_RS14655"
                     /old_locus_tag="B1H29_14730"
     CDS             complement(19245..19601)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986392.1"
                     /locus_tag="B1H29_RS14655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14730"
                     /product="YciI family protein"
                     /protein_id="WP_055418324.1"
                     /transl_table=11
                     /translation="MPRYLSLIRIEESDALSGGPSPELVERMEKLMDEMTKAGVLLDTA
                     GLTPTAQGTRVHYEGGRLSVTDGPFTESKEVIGGYSLLQAKDKAEAIEWTKRFLKTHEE
                     YWTVTCEVRELMEG"
     misc_feature    19570..19583
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    complement(19695..19709)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.08"
                     /tool="antismash"
     misc_feature    19696..19710
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.51"
                     /tool="antismash"
     gene            complement(19712..20731)
                     /locus_tag="B1H29_RS14660"
                     /old_locus_tag="B1H29_14735"
     CDS             complement(19712..20731)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974217.1"
                     /locus_tag="B1H29_RS14660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_14735"
                     /product="LCP family protein"
                     /protein_id="WP_055418325.1"
                     /transl_table=11
                     /translation="MAARGGPGGRSRGLRAAGLALVGALLLGAAAAGWAYWHLNGNITS
                     VDIDGALGDDRPARPVTAPSAPPSAPAGALNLLVLGSDSRGGEENQELGGGDSEGARSD
                     TAMVVHLDAGRTAATVVSIPRDTLVTRPSCPLPSGGETREASGAMFNTAYALGGPVCAV
                     KTVESMTGVRMDHYIEIDFSGFAKLVDALGGVTVTTDVDIDDDKSHLHLDAGTHHLDGT
                     EALGLARTRYGLAGGSDLARIELQQKLMKALLEQISATDLLTDPARLYQVTDAVTGSLT
                     TDTGLDSLGELMSLGRSLGGLSAADVRTVTMPVLPAPRDANRVVARQPDAGDLWKSLR"
     misc_feature    20791..20804
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(20848..20862)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
ORIGIN
        1 gatcagcgcc tgggcgcgct cgaaggcgtc accggcgaca ccgaccgcgg caccgaccag
       61 cagccggccc ctggcgtcct tggcggcgtg cgggtacttc tcggccttga cgaagtcctt
      121 gaccgtgatc aggcccttga ggacgccgtg gtcgtcgacc agcggcagct tctcgatctt
      181 gtggcggcgc agcagctcca tggcgtccac gccggagatg ccgaccttgc cggtgaccag
      241 cggcatcggg gtcatgacct cgcgcacctg acgggagcgg tcggtctcga aggccatgtc
      301 gcggttggtg acgatgccga gcagcttgcc ggcgccgtcg gtgaccggga cgccgctgat
      361 gcggaacttg gcgcacagcg cgtcggcctc ggcgagcagg gcgtccgggt ggatggtgat
      421 ggggttggcc accatgcccg actcggagcg cttgaccagg tcgacctggt tggcctggtc
      481 ctcgatggac aggttgcggt gcaaaacgcc gacgccgccc tggcgggcca tcgcgatcgc
      541 catgcgcgac tcggtgacct tgtccatggc ggcggacagc agcgggatgt tgacccgcac
      601 gttccgggag acgtacgagg cggtgtcgat ctcgtcgggc gccatgtcgg acgcgcccgg
      661 caggagcagc acgtcgtcgt aggtcagccc gagcgtcgcg aatttttcgg gcactccgtc
      721 gacgttggca gtcatgacac cttccccaaa tggccttgat cggtgcggat gtccatgcta
      781 acgggaagtg gacgtggctc attccacgat caaggacgcc catcgccttc gtagcttcgt
      841 acggacatcg gtcaccgtcc gttcatgtcc ggcgctactg ctccgccagg gcccgcaacc
      901 ggctcagcgc ccggtgctgg gcgacccgca cggcaccggg tgacattccc aacatctgcc
      961 cggtctcctc cgccgtgagc cccaccgcga tgcgcagcag gagcagctcg cgctggttct
     1021 cgggcaggtt ggccagcagt ttcttggccc aggcggcgtc gctgttgagc agcgcacgct
     1081 cctccgggcc cagtgagtcg tccggccgct cgggcatctc gtcggacggg acggccgtcg
     1141 agccggggtg ccgcatggcc gcgcgctgca ggtcggcgac cttgtgggcg gcgatggcga
     1201 agacgaacgc ctcgaaggga cgcccggtgt ccttgtagcg gggcagcgcg agcagcaccg
     1261 cgacgcagac ctcctgggcg aggtcctcga cgaagtgccg ggcgtcgccg ggcaggcggg
     1321 acagccgcgt gcggcagtag cgcagcgcca aggggtggac atgggcgagc aggtcgtgcg
     1381 tggcctgctc gtccccgtcg acggcacgat ggacgagccc accgaccgtc ccttggtcag
     1441 gggcagcatc gtcgtcacgc atcggtccat ggtgccttgc ggccgtccga tccgtggctc
     1501 cgtgcccgtt gttgtgcacc gaagcgttat gagcaggtgc gccggaactc atcccctgcg
     1561 ccctcccctt ccgctcgacc gactcgtccc cgaggaactc cacacctcaa ggatgcgtca
     1621 tccgcgccga aacgagcagc gggcacccgg cgggtcgcct tgtcaccccc gcccacctcg
     1681 cgataagcgg ggatcgcggc atccccgacg ggcccttccg gcctccaccg cacggggtgc
     1741 tcctagcgga ccaggcccca ccggaagccg agcgccaccg cgtgtgcccg gtccgaggcg
     1801 ccgagcttct tgaagagccg ccgggcgtgc gtcttgacgg tgtcctcgga gaggaacagc
     1861 tcgcggccga tctccgcgtt ggagcggccg tggctcatgc cctcgaggac ctggatctca
     1921 cgcgcggtga gcgtgggcgc ggcgcccatc tcggccgagc gcagccggcg cggggcgagc
     1981 cgccaggtcg ggtcggcgag ggcctgcgtg accgtggcgc gcagttcggc gcgcgaggcg
     2041 tccttgtgca ggtagccccg ggcaccggcg gcgaccgcga gggccacgcc gtccaggtcc
     2101 tcggcgacgg tgagcatgat gatgcgcgcg ccggggtcgg cggacagcag ccgccggacg
     2161 gtctcgacgc cgcccagacc gggcatgcgc acgtccatca gaatgaggtc cgagcggtcg
     2221 gcaccccagc ggcggaggac ttcctcgccg ttggcggccg tcgtcacacg ctcgacgccg
     2281 ggcacggtcg cgaccgcgcg gcggagcgcc tctcgggcaa gcggggagtc gtcgcagacg
     2341 aggacggaag tcatggccgt cctccgcagc aaatgcgcgt cacgttgagc ctccaggctg
     2401 gtacgaaatc gtcacctgtg cggtcgaccg tcccggacgc ccgcccgagc acttgttcct
     2461 tcaaccgcct ccgcactctc aacgacggtc actcgaaaga gttacggggc tgtgtgtcgt
     2521 cttcggcact ctacgtgagg gggcggccac gcagcagaca tgcgcgtcgg acccgccccg
     2581 tttcatcaca accggtgccc catttagctg cttttcttcc acttcgctgg tgtctgcggc
     2641 tagattcgca atgagtcata ttttcatctc cttagatcgt agttgtacgg tcgtggacac
     2701 cgtatccacc cagatcggct acaaggggtc acgcaatggc agatttctcc cgccttcccg
     2761 gaccgaacgc ggacctgtgg gactggcagc tcctggctgc gtgccgcggg gtggacagct
     2821 cgctcttctt ccatccggag ggcgagcgcg gtgcggcgcg gagtgctcgc gagaactcgg
     2881 ccaaggaggt ctgcatgagg tgcccggtcc gcgccgagtg cgcggcgcac gcactggcgg
     2941 tgcgtgagcc gtacggcgtg tggggcgggc tgaccgagga cgagcgcgag gagctcatgg
     3001 gacgggcccg aaaccgcctg gtggcggcga cggcatcggc gtcggccggc ggggaggcgg
     3061 ccgcacatca ctgaaggaac gtttctttat cgagtttctt tatcgagagg tcccgacacg
     3121 cgcgatcgag ggtcccgacc cgcgcgggtg cggcgccgcc gcgtgggtgg tagcggcgcg
     3181 tggatgtacc cgtgccctca gcaccccggc accggggtgc gcccgtgctc tcagcgcgcc
     3241 gccgactggc ctgcccccgc ccgggccagc tcgtccagcg tcgccgtcac cgccggcacc
     3301 tgggccaggt cgggcagggt gagcgcgacg atctcccgcc gcaccgcagg ctccagcgtc
     3361 accgtgcgta caccgcgggg ccgtacggac tcgacggcga gctggggcag gacggccact
     3421 cccagaccgg cccccaccag gccggcgacc gccggatagt cgtcggtcgc gaagtcgatg
     3481 cggggcgtga agccggcccc ctcacagacc tcgaccaact gcccccggca ccgcgggcag
     3541 cccgcgatcc acgggtcccg ggccagctcc ccgatggcca ccgaaccgcc gggttcggtg
     3601 cgcgcgagcc ggtgccgttc gggcaccagg gccacgaggc ggtcggtcag cagcggccgt
     3661 acgacgaggt cgtcccactc ctccgcgccg gccgcgccct cgtagcggaa ggcgagcgcc
     3721 acgtcgcagt cgccctcgcg cagcagctcc acggacttcg gcggctcggc ctcctccagg
     3781 aagacccggg tgccggggtg cgcggctcgc agcgcggcca gggcggacgg tacgagggtg
     3841 gagctgccgc tggggaagga gaccagccgg acccggccgg cgcgcagccc ggcgatggcg
     3901 gcgacctcct cctcggcagc ggtcagcccg gcgatgatcc cggcggcgtg ccgcaccagt
     3961 gcctcaccgg cctgggtcag ccgcatctcg cgcccggtgc gcacgagcag gggggtgccg
     4021 acggaggcct ccagggcctt catctgctgg ctgacggcgg gctgggtgca gcccagctcg
     4081 cgtcccgcgg cggagaacga accggtcgat gccacggcgc gcaggacacg gagatgacga
     4141 gcctcgatca cgcttccgag gataggcgac gataagcgac cctttgaccg ggcgccgaat
     4201 aacgcgtcga cgctttgatg acgattgtcc taccgttccg ccatgaagct tctctccgtc
     4261 aacgtgggcc gtgccagggc cgtgccgtac acggaccacc ccgagggcgt caccggcatc
     4321 gacaagcggc cggccgacgg gaccgtccgg gtgacggcgc cggggccgaa gggggccggg
     4381 gcgagcgggc tggccgggga cacggtgtgc gacacacgcc atcacggcgg cgccgaccag
     4441 gcggtgtacg ccgtggcacg ggaggacctc gacgactggg aacgcgagct gggccgcccg
     4501 ctgccgaacg gcgcgttcgg cgagaacctc acgacgacgg gcctggacgt ctccggcacc
     4561 ctgatcggcg agcgctggcg gatcggcccc gacctggtgc tggaggtgac cagcggccgt
     4621 atcccctgcc gtaccttcca gggccacctg ggtgagcggc ggtgggtgag gcgcttcacg
     4681 gagaagggcg cgccgggcgc gtacctgcgg gtgatcgagc ccggtgcgat acgggcgggc
     4741 gacgccgtcg agatcgtgca ccggcccgcc cacgaggtca cggtggcgtt gcagttccgc
     4801 gccgtgacga ccgaacggga gctgctgccg ctcctgctcg cggcgggtga ggcgctgcac
     4861 ccggaggcgt tggcggcggc gcggaagtac gtggaggcgt acggcgcctg agcgaaacgg
     4921 atctgctcgg tccggcccca taaccttgcg ccatgacaac ggcattgatt acgggatcga
     4981 cggcgggcat cggcgccgcg ttcgcgcggc ggctggcggc cggcggacat gacctggtgc
     5041 tggtggcccg cgacaccaag cggctgcgcg aacaggcgac cgaactgcac gaccggcacg
     5101 gcatcgaggc ggaggtcctg acggccgacc tggccacgga caccggcatc gaggcggtgg
     5161 ccgcccggct gggtgagcgc aggagccccg tcgacctgct gatcaacaac gccggcttcg
     5221 gcaacaaggg ccgcttcctc gacgtctcga tggccgacga gctgacgatg ctcaaggtgc
     5281 actgcgaggc ggtgctccgg ctgacctcgg cggcgacggc ggcgatgcgg gagcgggggc
     5341 gcggcggcgt ggtcaacgtg gcctcggtcg ccgccttcgt cccgcgcggc acctacggcg
     5401 cgtccaaggc gtgggtcgtg cagttcacgc agggtgtggc gaaggacctg gccggcagcg
     5461 gcgtacggct gatggccctg tgccccggct tcgtgcgcac ggagttccac gagcgggccg
     5521 ggatgggcac ggacaacatc cccaactgga tgtggctgga cgctgacaag ctcgtcaccg
     5581 cggcgctgga cgatctcgcg cgggggaagt ccctgtcgat tcccgacccg cgctacaagg
     5641 ccctgatggg cgccgcgaag ctggtgccgc gggggatgct gggcgggatc acgtcgcgga
     5701 cggggcggaa gtacgggccg cggtaggggg cgcgagccgc gccgcacacc tccctcctcg
     5761 gcggcgggct tgcctgaacg gtccggcacg gccacgtact tgtcgagcat gaccaggacg
     5821 tgcggcgtca ccgccgtctc ggagaatccg ctctcgtaga ggcggctgag gtgggtcgcc
     5881 gccagcccca gccacgcagt ggtctgctcg cccgcctccc actcgcccgc gctgtcctgg
     5941 atcgcggctt ggacggtctt cccgaacgtg cccaccaggg cggcgggggg ctgtacgagg
     6001 gccggtgggg gaatgtcacg gacggcgagc tgccgttcga cgcgtacgta tggccgcggc
     6061 aggcctgccg ccggactgcg agttgcccga ggcggatggg gcgccttcct caccggtgcg
     6121 gcagccacag gattcttccg gcgggaggtg cttgcgccac ggttctgcga ccgcgcaccg
     6181 tcccgcttgc gctgccgagc gcggtcgccg acggagacgg tcggctacct gtcgagttcg
     6241 gcccaaggtc ggcggtgagc catccggaca gccggccaag agggccgcca ccgtcgaaaa
     6301 aatcaccggc caggtcgacg cggtaggacc atcgccccca ttccgagcgg gctgcgtacc
     6361 tctgcccgat cctgcgcagg gtggctctca tcctctcgta cggcacttgc cgtccgtcca
     6421 ggctgtacga cgttcgccgc cgtgcggcct cgatggcgag cgcgatcctg tgcacgggcg
     6481 tcggggccgc ggtctcccgc aacgacacga tgccgaccca ccggttcatg gccctccccc
     6541 acggagccgc ggcccatacc gcaccggcgc gcgtcgccgc gctcccttcc ggtgtccggt
     6601 tggttccctg gccccttcgt tctccccagc cccgcacggt ctccacaccg ccggagcgag
     6661 tgatccccag gtgaccgtcc ggccagcgtg atcggtggac gacgcggcgt gaacggtctc
     6721 ggcggacttg atcgtccggc agggccctgg tcgggccggg tgacatcgag cgagcacggc
     6781 cagagcggca cccgtgcggt ctgagtgaag ggaggcggtg aggactcgag tcactgtgcc
     6841 gcggcgatcc tgcgacgaat cgcctcgagc catccttgca gggacatccc tcgcggcggc
     6901 aggaggtctg ccagcccaac cacccgtcag gttggaagag gttccgtggt agaggtgcgt
     6961 cgaacctggt cacggggcat cgaaattggt cacggctagc gccttgtcca cccgagcggc
     7021 ggccaagtcg tcgtggcgga tcacaaaact cgtgtagtac tcctcgtaga cccgcgcttc
     7081 actggcgagc gatatccatt cgctcgtcag ccggtgcttc tccttctcca ggtgggaata
     7141 ccatttcgcg atcgggacgg ctgggatctc gcctgccttc tcgcgtcccg cgagggtctg
     7201 ctccgcaatg ctgttgatca cctcgtcatc ggcatacccg ccgatgacaa cgccagcgcc
     7261 agatggccag aggtcgtggg ccaggtcccg aagtttgttc aggtgcggca ggtcacgctc
     7321 catgtatcgg accaactgct gctggaaggg cgacatgtcc tcccaatcga gatcctccca
     7381 gtactcgtgc cagtcatcgt cctcgtcgcc ctcctggagc caaaggggca gttcggctct
     7441 gagctcggcg ctgacgtcga gctgctcgcg gacacccacg gagccggggg cttccgcgac
     7501 cgcggtttcg gtgccgtccg gtacatatac gactcgcgcg tacctcccgg aactgtcctc
     7561 atggtccatc tcctggtcca cgaagaagag cagcgtcccg tcctccggca ggtcgaatcc
     7621 gtcgactctc ggcagcgccc cacaatcgac ggaaaagagc aacggcaacg gactgtcccc
     7681 ggcggacggc cacttcatgc ccaccggcag ccggggcaac ccaccgaact gcccgaccgg
     7741 agaaccaccg cccaccccgg acaacccgat cgacaaacga aggtgctggg tgaatctgct
     7801 gacctcgtcg tccgggatgc ccaactcaag cgctgcccga cgaaactctc cctgatgatc
     7861 catgcccgag aagataaccc tttccaacgc gactgaacca tcggggtgtt ggtgggcatt
     7921 ggctgtacgt ggtggagcta gcggctggtc accttggatc atcccagcgg atccggctcc
     7981 aggaagccgc acatctccaa ggcggggtta cgcatgccct ctccgggagc gtgatcagtc
     8041 ctgacttcga agtgtcaccc gtcgtcaggg aatggatggt gcagccccct gtcagttgga
     8101 catgaggttc cacgtgcttg gccgagaccg tcagatctcg ttccaaggaa caccaggctc
     8161 gggcaccgtt ccacccacgg gagtcttccg ccggctctgc cgaaaacaca tcgagtccat
     8221 cgccgccccc cgtcgtcgcc gggagtgagg ttggaaaagg ctcattccct tggtcaacgg
     8281 cggttccaag gacccggcgg gctctgggtc acccaacagc tcgtctccag cgtgcccttg
     8341 ggcgacgccg aagccgtcaa gctgctcgcc cagatgcccc tggggccgcc gggacgacca
     8401 ccaccgaacg cgtggcgccg ccgcagctcg caccggggca tcgttgtccg gccgtcggtc
     8461 agccggccac cccgcccacc gacggttatc caccgcaaga ccttgaagga aacacctcca
     8521 accaaccccc caagcccccc gcaccgcccc gagccggacc ggacgcgcag gccccgcagc
     8581 cggacgacga cgcacccccc gagccccagc tcaccgcagc tcgctccctc gtcgacgcct
     8641 tccccgccct ctcccccgac ctgcgccaca tcccccgcgc catgcgcccc gagctgacgc
     8701 gcctcaccgc ccgctggctg gccgccggtc acccgcccac cgccgtccgc acgcacatcc
     8761 tgcgcggcct gcccgacgac ggcacccccg tccaccgccc cggcggcctc ctacgccacc
     8821 tgctccgcga cgtaccgccg tcgccatcgc cacccgcacc ggctgaccgg cccgccacct
     8881 cggcgccacc gcaccccgac gaccgccccg cccggcagca acccccgggc ccacgcctct
     8941 cccaccgcct cgcaggcacc cgcgaatgcg cgggcgacca tgtgcaaccg ctgctcttca
     9001 ggcccgtggc ggacgagacc cactgcccgc gttgccgctg accgcaaggg tttcccccgg
     9061 agaccgtgaa ccgccccgtg tcggttcgag gtgtcgctca tccacggact gcaagacggt
     9121 cgctacgtag agcgaaccac ggcactcgcg ggtacgacca cccacctgga cgccccgttc
     9181 ccgatcgcga tcgatccggc tgacctctcg cggcagtaga gcaccgggga gacgaggcag
     9241 cgcggaactg cccacgttgc cgctgacggc gggcagggtt cagccggcga cccggggcac
     9301 gccgcccttg cggcccacgc cgaaggcgat gcggtagacg tccggcaggt cgatgcggcc
     9361 gtcgcggcgg cggcgcatca cgcccaggcc gatcagttcc tcgatcagca gtttctggtc
     9421 ctccggacag cgagggccgg tccgcacctt gatctcgtcg tcgttctggg gctcgtagcg
     9481 ctcagtggtg ctgctctgag ttcaccggca cggcacggtt ctcagggctc atgtcactcg
     9541 gacggcccag ctctggtgca cgcggtgcac gcacgggatc gtcacccgaa cgtgtggtcc
     9601 attccggtcc cgccccggcc gaggcggcgg gaaacgtagc gtcaggtggc tgcgcccacg
     9661 cagcgggtgg ggcaggcaga caggcagggg aaaggggcat cgggtgagcg cgggcacggg
     9721 tgaccggggc ggactgttcg tcgacggcgc cgacagcggg cgtgagagca ggggtggtcc
     9781 gggccggggg gcggtggccg gcggggggac ggtgatgttc tccgacgccc ccggcgtcgg
     9841 tgggtcgccg tcgacggttc ccgcctcggg gcgccccggt gcggccgatg ccggggctgc
     9901 ttccgtcccg cgtgctcggc ccgccccgcg tccccgggcg ggcggtgtcc ctgccgggcc
     9961 cctgggttcg gggcggtggg ggaagatcgc gcagcggatc gtgccggacg acctccagcc
    10021 cgatgtactg cgcctggagc tgaccgaact cggggacgca ttccgcgcgt atcagcggcg
    10081 ccccgaaccg gacctcgccg tcctcgccga actccacgac cgcaaggccc gcgcgttcgc
    10141 gttgtgggcc gacgtcaccg acgacgcgtc cctgtgggag gaggccgtac gtgcggaagc
    10201 ggcggcgcgg accacccgcg agatgaacgc caaccgcctc ggcatcgagg tggacgggga
    10261 cggaccggtc gtcgaccggt tgctgacccg gggccagggc gctcacgccc gtggcgtgct
    10321 ggagtacgtc cgggcccacg ccccgctccc cggggccgag gcgcggctcg cggtgctcat
    10381 gctcaccctg cgggccgcgc gcgccggcac cgggaacgtc accggacagg atctcagcgg
    10441 ctggttgcag ggcgatgccg agcgggtgat ccaggaactc gccgacgtcg gctggctgcg
    10501 tctgccggag ggggtcgacg ccgccgacgc gctggactcc cggcccgagg aacccaccca
    10561 ggtcaccgtg ccctcgctgc tgcccgccga gccgcgcccg atccccttcg gcaagatcac
    10621 tcgggcgcgg ctgtcggggt gggcgcagaa ggtggtggga gaccggaagc tgcggaagaa
    10681 gaaggcgggc gccgccaccc ggctcctcgc cgtgtacacc gccgcccaca gccgtcccga
    10741 cgggcggctc ggtgagcggg tcggtgagcg ggtcgaaggc gccgcgggcg acggtgtcgg
    10801 cctggacgcg gtcgcctcgt tctgtggcct acggcccgag gatgtcgccg agcacgccga
    10861 ggtgctggtc gccgccggct ggctcgcgga cgcctccgcc gccgggggca ggctgcgggg
    10921 gcggctaggc gcgcgggtcc tgccgctgag cgggctggtg tgaccggcca ccccgacaga
    10981 cggcgcaccg accgctacag atggcggccg tagggccgaa tcacctggtc aggcaggcca
    11041 ccggagcggg atcttcgagg caggaccacc gcttccaccg gcgtcacctc cttcgcggcg
    11101 ttggccgcgt cgccgtgact gaagctcgtc cagcagctcc tgcagcgcaa cgccgacgcc
    11161 gccgtgggcc ggctgatccc cctcggcgac ctgtgggacg tgctcgtcga cggcacgggc
    11221 gccgccttca ccgaccggct caagcgcgag tcggaggccg ccgtgaagtt ctacgccaag
    11281 gcgcgcaccc acctgctcgg caagtacggc tccgacaccc acaccgactt cctggccgac
    11341 caccgttcgt caggacgctg ctgctgggcg cgctcgctcc cgacgtgccc gcgctgcgcc
    11401 ggctgacggg cgcacggctc gcggccctca accacggctc ggtgcgctcg cggaccgtgc
    11461 ccgccgggga cgtcgtcgta cggcggatgc gggacctgcg cgacgacgtg accgcgccgc
    11521 cgtggcggac ggcggtggcg gacgccggga cggggcgcac cctgcccgaa gtggaccccg
    11581 acgcggtccg cggcctgaag ttcgccgaag cccttcctcc gcgcctggcg gaggccaccc
    11641 tcgcggcgcg cctgacggat gaggaaggcg cccgagcggc tctcgcggag cctgtgcgtt
    11701 cgtcagggga acagccccgt agggagcgcg tcgccacacc cggcgacgag ctccgccggg
    11761 cggacgcgca cccggtgccg tgaacgcacg gtgcccagca cccccgtagg ggtactgggc
    11821 accgtcggct cggtcggccg ggctcagctc agcgcagcgc tcagtgggcg tggccgtggc
    11881 cgtggcccgc ggcggccggc tcttcctctt ccttcttctc gacgaccagg gtctcggtcg
    11941 tcaggaggag ggaggcgatg gaggccgcgt tctccagggc ggagcgggtg accttcaccg
    12001 ggtcgatgac gccggccttg accaggtcgc cgtactcgcc ggtggcggcg ttgaagccct
    12061 ggcccttgtc gagctcggcg accttggagg tgatgacgta accctccagg ccggcgttct
    12121 cggcgatcca gcgcagcggc tcgacggcgg cgcggcggac gaccgcgaca ccggtggcct
    12181 cgtcgccggt cttgccgagg ttgccctcga ggaccttgac ggcgtggacc agcgcggagc
    12241 caccaccgga gacgatgccc tcctcgaccg cggcgcgggt cgcggagatg gcgtcctcca
    12301 gacggtgctt gcgctccttc agctccacct cggtggcggc gccgaccttg atcacgcaca
    12361 cgccgccggc cagcttcgcg aggcgctcct ggagcttctc gcggtcccag tcggagtccg
    12421 tggcctcgat ctcggccttg atctgcgcga tgcggccgtc gacctcgtcg cgcttgccgg
    12481 caccgtcgac gatcgtggtg tcgtccttgg tgacggtgat gcggcgggcg gtaccgagca
    12541 cctcgaggcc gacctggtcg agcttgaggc cgacctcctc ggagatgacc gtggcgccgg
    12601 tgaggacggc catgtcctgc agcatcgcct tgcggcggtc gccgaagccg ggggccttga
    12661 cggccaccgc gttgaacgtg ccgcggatct tgttcacgac gagggtggag agcgcctcgc
    12721 cctcgaggtc ctcggcgatg atcagcagcg gcttcgaggc gttggcctgg atgaccttct
    12781 ccagcagcgg cagcaggtcc gcgatggagg agatcttgcc ctggttgatg aggatgtacg
    12841 ggtcctcgag gacggcctcc atgcgctcct ggtccgtcac gaagtacggc gacaggtagc
    12901 ccttgtcgaa ggccatgccc tcggtgaagt ccagctccag accgaaggtg ttggactcct
    12961 cgacggtgat gacaccgtcc ttgccgacct tgtccatcgc ctcggcgatg agctcgccga
    13021 cctgctggtc ctgggcggac agcgcggcca cggcggcgat gtcggacttc tcgtcgatcg
    13081 ggcgcgcggt ggcgaggagg tcctcggaca cggcggcgac ggccgcgtcg atgcccttct
    13141 tcagcagcgc cggggaggcg ccggcggcga cgttcctcag gccctcgcgg accagtgcct
    13201 gggccagcac ggtggcggtg gtggtgccgt cacccgcgat gtcgttggtc ttggtcgcca
    13261 cctccttcac gagctgggcg ccgaggttct cgtacgggtc ctcgatctcg acctcgcggg
    13321 cgatcgtgac accgtcgttg gtgatggtgg gggcgccgaa cttcttgtcg atgacgacgt
    13381 tgcggccctt ggggccgatc gtcaccttca ccgtgtcggc aagcttgttg acgccgcgct
    13441 cgagggcgcg acgggcgtcc tcgtcgaact tcaggatctt cgccatggga gcgtgagccc
    13501 tcttccggaa attttggggt tctacggcac tgcgcccccg acacccggct ttttatggac
    13561 gcgggagcca ggggcgcagc tggaaagcaa ggtgcttcgg tgaactactt ctcgacgatc
    13621 gcgagcacgt cgcgggccga gaggacgagg tactcctcgc cgttgtactt cacctcggtg
    13681 ccgccgtact tgctgtagag cacgacgtca ccgacggtga cgtcgagcgg aagacggttg
    13741 ccgtcctcga agcggcccgg gcccacggcc aggacgacgc cctcctgggg cttctccttg
    13801 gcggtgtccg gaatgaccag gcccgaagcc gtggtctgct cggcgtcgag cggctggacc
    13861 acaatgcggt cctcgagcgg cttgatggca accttggagc tggtggtcgt cacgatccga
    13921 cctccccctt cggagatctc acggggttaa ctgtctgagg tggcgaccag gtggatccgt
    13981 cgtcgcgggt gccggacctg cccgtcgcgt agttggcact ctccagtggg gagtgccagg
    14041 tccgagacta tgaccgcgat tagcactcgg tcaagcggag tgccaatgcc ggcggcgcgt
    14101 cggcggtatt tcggcgcaag cggggggtcc gcgggctgcc gcccccggca tcgagaagtc
    14161 agaggtagtc ccccaggcgt cccacccgca gcccctgctc ctcgatctcc gccagcaaac
    14221 gttccgtgcg ggcactcagg cccaggcccg tcgggtggtc cggggcgacg gacacgatgt
    14281 cgccggggtg gaggcgggcg ttgccgcggg tgtaggtgag gtcgccgccg gggttcagga
    14341 ccgcccgcca caggacgacc gccgtgatgc cgcagtcggc ggcggcgcgc agggtggtgg
    14401 tgtcgtacct gccgtggggc gggcggaaga gatgcgggcg gacgccgaaa cgggatttga
    14461 gcttggtctg ctggccgcag atctcggcgc gctggccggc gtagggcagg ccgcgcaggg
    14521 agcggtggtc cagggtgtgg ttctgcaggc tcgcgccgac cgagcggagc cgggcgaagt
    14581 ggccgtacgc cggtccggcg acggtgtcgg tgaggaacag ggtgaccggg agccggtgtg
    14641 cgcggaccag gtcggcgaag tgcgggtcgc gctcggcgct gtcgtcgaag gtgaggaaga
    14701 cgacccggtc ggtggtgcgg acgtggtcca cgacgggcgg caggttctga ccccggtagc
    14761 tgccctgagc gggctctccg gccgccggct gctgcgcggg gccggctgac tgggcgcagc
    14821 cggtgagcag tacggcggcc agggcggccc cggcgggccg gaaccgcccg cgcctcacag
    14881 gtagtcctcc agccgggcca cggcgtatcc ctcggcggtg accttgtcga ggaactcgcg
    14941 caccatgtcg cgcatggtgc cgccccagtc gtcctcgccc cggaagtggg tgaggacgat
    15001 gtcgccgggg tggatctccc ggtcccactc gcggtagtcc cagtggtcgg cgaagacctc
    15061 ctcgttccag atcggggcgt actcgatgcc acaggccttc gccgcgcgca gggtgtcgcg
    15121 gtcgtagttg ccgtagggcg ggcggaagac ggtggggcgc ttgccgtagc gcttctcgat
    15181 cacgtcctgc ataccgcaga tctcgcgctt ctgctcggcg taggacaggc cgggcaggta
    15241 ggggtggtgg agggtgtggt tgttgagggt gacgcctctg tcctgcatct tcttgaagta
    15301 gccgtagtcc tccttcgcca ggtagtcgct gaggaaggcg gtgtacggga tcttcagctc
    15361 gctcatcatc cgcaggaacg ccgggtcctt ctcggcgccg tcgtcgatgg tgaggaagac
    15421 gatcttctcc ttggtcggga tcgaggtgaa gaccggcggg aggttcttct ggccggtcac
    15481 ctcgaagcct tcgcgcgcct tgatctccgg cttgcgggcc gggggcggcg gggccgtcag
    15541 cgggaccttc ttcaggttcc agcgcttggc ggcggcgacc cgggcggcct gggccgcgcg
    15601 cagcttggac gcgtaggcgt cgagcgctcg ggccgggggc gcctggaggg gctgccggcc
    15661 ggcggcgccc cgcacctcgg aggcgtcctg cgcacagccg gaggcgaggg cggcgacggc
    15721 gagcgcggcg acaccgccgc gcatccggag ccctggtgaa gacgcccgga acaccctgac
    15781 cgcccggctt ttgtcatttt gtacgactgc tcgcatggtg ccggatcctc gcagtccccg
    15841 gccgccgaac ccggcccgac accgcgccgc aggcacacca tccaccgact ggcccacaat
    15901 gttccggtga acgacctcga cgccctcctc gccctgctca cccccgaggg ccgcgccctc
    15961 ctcgacgagg tgcgcgacac cgacccggcg cgggaactcg cggtcgccac ccggctgcgg
    16021 cgggcgcacc ccgccgagct ggtgtcggcg gccctcggac aggcgcggct gcggcaacgg
    16081 gcggcggcga agttcggggc cgaggacgcc gggcgcatgt tcttcacgcc caacggggtc
    16141 gagcagtcga cgcgggcgag cgtggccgcg taccgggccg ggcggatgtc ggtcctgggc
    16201 gtgacctcgg tcgccgacct gtgctgcggg atcgggggcg acgcgatcgc gctggccagg
    16261 gccgggatcc gggtgctggc cgtggaccgg gacccggcga cggccgccgc ggcccgcgcc
    16321 aacgccgagg ccctggggct ggctgagctg atcgaggtgc gcgaggcgga tgtgaccgag
    16381 gtggacacga gtgggtacga cgccgtgttc gtcgatcccg cgcggcgggg cgggcggggc
    16441 cgcgtcttcg accccgaggc gtactcgccg ccgctgtcct gggcggtcgc ggcggcccgt
    16501 acggcctccc gcgccgccgc gctgaaggtc gcgccgggca ttccgcacga ggcggtgccg
    16561 gacggcgccg aggcggagtg gatctcggac ggcggggacg tgaaggaggc cgtcctgtgg
    16621 ttcggcaccg cgccggggac ggtgcgggcc acgctgctgc cggggccccg caccctgctc
    16681 ggcaccggcc tgcccgaccc gggggtccgc acgcccggcc ggtacctgta cgagccggac
    16741 ggcgccgtca tccgtgccca tctggtcgcc gaggccgccg agcgggtcgg cggcgggctg
    16801 ctggacgcga ccatcgccta cgtcaccgcg gacgagctgg tgccgacgcc gtacgccagg
    16861 gcgtacgaga tcaccgaccg gatgcccttc aacgtgaaga agctgaaggc gttgctgcgg
    16921 gagcgccggg tgggcgtcct gaccgtgaag aagcggggct cggcggtcga gccggaggaa
    16981 ctgcggcgga aggtcaaacc ccaggggccg aacgcggcga cggtgttcat gacccgggtc
    17041 gcgggggcgc cgacgatgct gatcgggcac ccggtgcgct agcggtctag atcaccagcg
    17101 gggcggtcac gggcggtcgg cggtcgaggg cgcggggtgc tcggcgggcg cgggcggtcg
    17161 cgggcgggcg cgggcgcggg cggacgcaga cgctcggcgg acggcggacg gcgggcgcgg
    17221 gcactcggcg gacggcgggc gcgggcactt ggcggacggc gggcgcgggc ggcgggcacg
    17281 ggatgctcag ccgtcgcggg cgcggggtgc tcagcgggcg cgggcgcggg cggacgcaga
    17341 cgctcggcgg acggcggaca gcggacggcg ggcgcgggca ctcggcggtc ggcgggcgcg
    17401 ggcggcgggc gcggaatgct cagccgtcgc gggcggacgc agacggacgg cggacggcgg
    17461 acggcgggcg cgggcactcg gcgggcgcgg gcggcgggcg gcgggcgcgg gatgctcagc
    17521 cgtcgcgggc gcggggtgct cagcgggcgc gggcggacgc agacgctcgg cggacggcgg
    17581 acagcggacg gcgggcgcgg gcactcggcg gtcggcgggc gcgggcggcg ggcgcggaat
    17641 gctcagccgt cgcgggcgga cgcagacgga cggcggacgg cggacggcgg gcgcgggcac
    17701 tcggcgggcg cgggcggcgg gcgcgggcac tcggcgggcg cgggcggcgg gcgcgggatg
    17761 ctcagcgggc gcgggcgcgg ggtgctcagc gggcgcgggc gcgggcgcgg gcgggcgcag
    17821 acgctcggcg gacggcggac gcggggcgcg tgcccgaagg cgtcgggctc cgggcgcggg
    17881 gcgcagcggg cagaccgcgc gaccggcgcg ggtgtcaggc ggggcgggcg gcacggctcg
    17941 cacgcctcag ccgcactccc gcgcccggcg cgcaagcagc tcgcgttcgc gctcgttgcg
    18001 tgccagggcg gcggcgcgct cgaactccgt ccgcgcctgg gccgtgcggc ccaggcggag
    18061 caggaggtcg ccgcggacgc tggggagcag gtggtagtcg ctcagggccg gttcggcggc
    18121 gagggtgtcg acgagggcga gcgcccgggc cgggccctcg gccatcgaca cggcgaccgc
    18181 tcggttgagt tcgacgaccg gggacggggc gcgggccgcg agcaggccgt agagcgtggc
    18241 gatgcgcggc cagtcggtct gctcgtacgt gtacgccgtc gcgtggcagg cggcgatcgc
    18301 ggcctggagg gcgtacgggc ccggggcgcc ggagccggag ccggcgtggg ctcggccgag
    18361 ggcggtgatg ccgcgggcga tgagcatgcg gttccagcgg ctgcggttct ggtccttgag
    18421 gagcaccggc gcgccgtcgg ggccggtgcg ggccgcggtg cgggacgcct gcaactccag
    18481 cagcgccgtc aggccgtgga cctcgggttc cttcggcatc agcgcgctga gtacccgggc
    18541 caggcgcagg gcgtcctcgc acagggccgg acggagccag tcgtcgccgg cggtcgccgc
    18601 gtagccctcg ttgaagatca ggtagatgac ctccaggacc gagccgaggc gggccgcgcg
    18661 gtccgggccg tagggcacct cgaaggcgac gttcttcgtg gccagggtgc gcttggcgcg
    18721 cacgatgcgc tgcgcgaccg tcggttccgg gaccaggaag gcgcgggcga tctcgggcgt
    18781 ggtgaggccg ccgagcaggc ggagggtgag ggcgatgcgg gcctcggcgg acagcaccgg
    18841 gtggcaggcg gtgaagacca gccgcagcag gtcgtcgtcg atgtcgtcga ctccggcggg
    18901 ctcctcgggc ggtgccgcct cggtgggcag gtcccggccg atctccgcca gcttgcgggc
    18961 gtagttctcg cggcgccgga tcaggtcgac ggcgcggcgc cgggcggtgg ccatgagcca
    19021 ggcgccaggg ttgtcgggca ccccgtcccg gggccactgc tccagggcgg cgaccagggc
    19081 gtcctgcgtg agttcctcgg cgaggccgac gtcccgcacg aggcgggcga cgccggcgat
    19141 gacgcggggc gactccaggc ggaagacggt ctcgagggcc tcggtgggct gtggttccac
    19201 agcccaccat gcaacaccct cggggcccgc ggggcgaaac tcggtcagcc ctccatgagc
    19261 tcccgcacct cgcacgtgac cgtccagtac tcctcgtgcg tcttcaggaa gcgcttggtc
    19321 cactcgatcg cctcggcctt gtccttggcc tgcagcagcg agtagccgcc gatgacctcc
    19381 ttggactcgg tgaacggccc gtcggtgacg gacagccgcc cgccctcgta gtggacgcgg
    19441 gtgccctggg cggtcggggt cagaccggcg gtgtcgagca ggacgccggc cttcgtcatc
    19501 tcgtccatca gcttctccat gcgctccacc agctcggggc tggggccgcc ggagagggcg
    19561 tcgctctcct cgatccggat cagcgacagg tagcggggca tgatgactcc tcggggtggg
    19621 tcggggaccg ggtccgtccc ggcctctcac cccatgcgtc gaacgggagg cacacggatc
    19681 gacacacgcc ccgggatttt ccggagattt ctcagcgcag cgatttccac aggtcaccgg
    19741 cgtccggctg ccgtgccacc acccggttgg cgtcccgggg cgccggcagg accggcatcg
    19801 tcaccgtgcg cacgtcggcc gccgacaggc ccccgagact gcggccgagg ctcatcagct
    19861 cgcccaggga gtccaggccg gtgtcggtgg tgaggcttcc ggtgaccgcg tcggtgacct
    19921 ggtagagccg tgcggggtcg gtgagcaggt cggtggcgga gatctgctcc agcagcgcct
    19981 tcatcagctt ctgctggagc tctatgcggg cgaggtcgct gccgcccgcc agtccgtacc
    20041 gggtgcgggc caggccgagg gcctcggtgc cgtcgaggtg gtgggtaccg gcgtccaggt
    20101 gcaggtggct cttgtcgtcg tcgatgtcca cgtccgtggt gaccgtgacc ccgccgaggg
    20161 cgtcgaccag cttggcgaag ccggagaagt cgatctcgat gtagtggtcc atgcggaccc
    20221 cggtcatcga ttcgacggtc ttgaccgcgc agaccggacc gcccagggcg taggcggtgt
    20281 tgaacatcgc gccgctcgcc tcccgggtct caccgccgga cggcagcggg caggacgggc
    20341 gggtgacgag cgtgtcgcgc gggatgctga cgacggtggc ggcggtccgg cccgcgtcga
    20401 ggtggacgac catcgccgtg tccgagcggg cgccctcgct gtcgccgccg ccgagttcct
    20461 ggttctcctc accgccgcgc gagtccgagc cgaggaccag gaggttcagg gcgccggcgg
    20521 gcgcggaggg cggggcggaa ggggccgtga ccggccgcgc ggggcggtcg tcgccgagcg
    20581 ctccgtcgat gtcgacgctt gtgatgttgc cgttgagatg ccagtaggcc cagcccgccg
    20641 cggcggcccc gagcagcagg gcaccgacca gggcgaggcc tgccgccctc agccccctgg
    20701 agcgcccacc cggcccgccc cgcgctgcca tgcgtccgcc cccgcccttg cccgtcccgt
    20761 tcgcgtcccc acccgaatgc cccatcggga ggaacataag tccgaattgt tgggagtgga
    20821 cctacgcggg tcgtgattct gcggaaattc tcagacttcg aaggccgacg aaggactcgg
    20881 gaaacgggga ggaagaagcg ggaggatgca ggagcggcag agggcggcgg aggggagccg
    20941 tggggcggag gggaagcagg acg
//
