LOCUS       NZ_CP019724            21167 bp    DNA     linear   CON 01-JUN-2024
DEFINITION  Streptomyces pactum strain ACT12 chromosome, complete genome.
ACCESSION   NZ_CP019724
VERSION     NZ_CP019724.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces pactum
  ORGANISM  Streptomyces pactum
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Streptomyces pactum ACT12 Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2017) College of Life Sciences, Northwest A&F
            Unversity, No.22 Xinong Road, YangLing, Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2016
            Assembly Method                   :: SMRT v. 2.3.0
            Assembly Name :: version 2.3.0 of the PacBio Single Molecule Real
            Time
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002005225.1-RS_2024_06_01
            Annotation Date                   :: 06/01/2024 05:58:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,315
            CDSs (total)                      :: 7,221
            Genes (coding)                    :: 6,992
            CDSs (with protein)               :: 6,992
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 229
            CDSs (without protein)            :: 229
            Pseudo Genes (ambiguous residues) :: 0 of 229
            Pseudo Genes (frameshifted)       :: 84 of 229
            Pseudo Genes (incomplete)         :: 195 of 229
            Pseudo Genes (internal stop)      :: 15 of 229
            Pseudo Genes (multiple problems)  :: 62 of 229
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:20:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3034284
            Orig. end                         :: 3055451
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019724.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Northwest A&F Unversity.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21167
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="20"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21167
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21167
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11167](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11167)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(264..473)
                     /locus_tag="B1H29_RS12165"
                     /old_locus_tag="B1H29_12240"
     CDS             complement(264..473)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384656.1"
                     /locus_tag="B1H29_RS12165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12240"
                     /product="HTH domain-containing protein"
                     /protein_id="WP_055417899.1"
                     /transl_table=11
                     /translation="MSEATDLAARAGDRDPRVGLRAVAALRRLLEQLEAVQVRSARNQG
                     WSWQEIATELGVSRQAVHKKYGRH"
     gene            complement(607..1572)
                     /locus_tag="B1H29_RS12170"
                     /old_locus_tag="B1H29_12245"
     CDS             complement(607..1572)
                     /NRPS_PKS="Domain: PKS_ER (17-318). E-value: 2.3e-34.
                     Score: 110.9. Matches aSDomain:
                     nrpspksdomains_B1H29_RS12170_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973708.1"
                     /locus_tag="B1H29_RS12170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12245"
                     /product="quinone oxidoreductase"
                     /protein_id="WP_055417900.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.4e-20, bitscore:
                     70.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAVYAARIDRDQPLTGLELGERPAPEARPGWSVVDVRAASLNHH
                     DLWSLRGVGLPEDRLPMILGCDAAGVDEDGNEVVLHSVIGQTGHGVGPKEPRSILTERY
                     PGTFAERVAVPTWNILPKPKELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAG
                     GGVATAAIVLGKAAGLRVFATSRDEAKRKRALELGAVEAVEPGARLSRRVDAVIETVGA
                     ATWSHSVKSLRPGGTLVISGATSGDRPSHAELTRVFFLELRIVGSTMGTKDELEDLLSF
                     CAATGVRPVIDEVLPMDRAREGFERMASGEQFGKIVLSGS"
     aSDomain        complement(619..1521)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B1H29_RS12170_PKS_ER.1"
                     /evalue="2.30E-34"
                     /label="B1H29_RS12170_PKS_ER.1"
                     /locus_tag="B1H29_RS12170"
                     /protein_end="318"
                     /protein_start="17"
                     /score="110.9"
                     /tool="antismash"
                     /translation="LELGERPAPEARPGWSVVDVRAASLNHHDLWSLRGVGLPEDRLPM
                     ILGCDAAGVDEDGNEVVLHSVIGQTGHGVGPKEPRSILTERYPGTFAERVAVPTWNILP
                     KPKELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAGGGVATAAIVLGKAAGLR
                     VFATSRDEAKRKRALELGAVEAVEPGARLSRRVDAVIETVGAATWSHSVKSLRPGGTLV
                     ISGATSGDRPSHAELTRVFFLELRIVGSTMGTKDELEDLLSFCAATGVRPVIDEVLPMD
                     RAREGFERMASGEQFGKIVL"
     CDS_motif       complement(1060..1113)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B1H29_RS12170_0002"
                     /evalue="6.00E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="B1H29_RS12170"
                     /protein_end="171"
                     /protein_start="153"
                     /score="15.7"
                     /tool="antismash"
                     /translation="GDSVLVQGAGGGVATAAI"
     CDS_motif       complement(1144..1182)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B1H29_RS12170_0001"
                     /evalue="5.60E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="B1H29_RS12170"
                     /protein_end="143"
                     /protein_start="130"
                     /score="13.4"
                     /tool="antismash"
                     /translation="AACLPTAWLTAYR"
     misc_feature    complement(1827..1839)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     gene            complement(1836..3065)
                     /locus_tag="B1H29_RS12175"
                     /old_locus_tag="B1H29_12250"
     CDS             complement(1836..3065)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997977.1"
                     /locus_tag="B1H29_RS12175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12250"
                     /product="NADP-dependent malic enzyme"
                     /protein_id="WP_055417901.1"
                     /transl_table=11
                     /translation="MAAEIVNPRSDSGASAEQEAGAEPLDSFDPAFALHRGGKMAVQAT
                     VPVRDKDDLSLAYTPGVAKVCSAIAEQPDLVHDYTWKSSVVAVVTDGTAVLGLGDIGPE
                     ASLPVMEGKAILFKQFGGVDAVPIALNCTDADEIVETVVRLAPSFGGVNLEDISAPRCF
                     EIERKLQERLDIPVFHDDQHGTAVVTLAALRNAARLSGRTLGELRAVISGAGAAGVAIA
                     KMLVEAGIGDVAVADRKGVVSADRDDLTPVKREVASFTNKAGLSGSLEAALSGADVFIG
                     VSGGTVPEPAVASMAKGAFVFAMANPNPEVHPEVAHKYAAVVATGRSDFPNQINNVLAF
                     PGIFAGALQVRASRITEGMKLAAAEALASVVGDDLAADYVIPSPFDERVAPAVTAAVAA
                     AARAEGVARR"
     misc_feature    3094..3109
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(3307..3317)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    3590..3605
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            3706..4668
                     /locus_tag="B1H29_RS12185"
                     /old_locus_tag="B1H29_12255"
     CDS             3706..4668
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973710.1"
                     /locus_tag="B1H29_RS12185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12255"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_055417902.1"
                     /transl_table=11
                     /translation="MTASSTRRTTAAHSRIAAVGAIAVAGALLLTGCGDQTESSDSGSS
                     DNQSAAGAPLADRLPQSIRDKGVIKVGSDIAYAPVEFKDKSGKTVGIDPDLADAMGKQL
                     GVKFEFENGTFDTLITGLRSKRYDIAMSAMTDTKDRQEGIDSDTGKKVGQGVDFVDYFT
                     AGVSIYTKKGDDQGIKTWADLCGKKLVLQRGTVSEDLAKAENEKCPAGKKISMQPFDND
                     QQAQTRLRAGGADAGSSDFPVAAYAVKTSGGGDDFQIVGEQVEAAPYGIAVAKDNTKLR
                     DALKAAMDAVIANGEYKKVLDKWGVAEGAVTEATINGGK"
     gene            4699..5649
                     /locus_tag="B1H29_RS12190"
                     /old_locus_tag="B1H29_12260"
     CDS             4699..5649
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973711.1"
                     /locus_tag="B1H29_RS12190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12260"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_055417903.1"
                     /transl_table=11
                     /translation="MTVDIDKTAGGPADTPPAGPEAIKAIPVRHYGRYVSAVVAIALLA
                     AVVYAFSQGKINWGAIPDYFFDDRVLTGMGKTLLITVLAMLIGVFGGILLAVMRLSKNP
                     VTSSIAWFYIWFFRGTPVLVQLVVWFNLGLVFEYINLGPFYRDEWSDFMTPFLTALLGL
                     GLNEAAYMAEICRAGLLAVDEGQTEAAHALGMSHTKTLRRIVVPQAMRVIVPPTGNEVI
                     NMLKTTSLVSVVQYAELFRVAQDIGQTSGAPAEMLFLAAAWYLLLTSVFSVGQYYLERY
                     YARGSSRSLPKTPMQKIRANLLSLSNRSSTTGGAA"
     gene            5646..6407
                     /locus_tag="B1H29_RS12195"
                     /old_locus_tag="B1H29_12265"
     CDS             5646..6407
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="B1H29_RS12195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12265"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_055417904.1"
                     /transl_table=11
                     /translation="MTAMVKAEGVHKSFGAVEVLKGIDLEVKQGEVFCLIGPSGSGKST
                     FLRCINHLEKINAGRLYVDGELVGYRQKGDKLYELKDSEVAVKRRDIGMVFQRFNLFPH
                     MTALENVMEAPVQVKGVSKAQARDRARQLLERVGLGDKAGNYPSQLSGGQQQRVAIARA
                     LAMDPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMVVVTHEMGFAREVGDSLVFM
                     DDGVVVESGNPRDVLTDPQHERTKAFLSKVL"
     gene            complement(6491..7270)
                     /locus_tag="B1H29_RS12200"
                     /old_locus_tag="B1H29_12270"
     CDS             complement(6491..7270)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326934.1"
                     /locus_tag="B1H29_RS12200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12270"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_055417905.1"
                     /transl_table=11
                     /translation="MTDADTTTTITTAADWRAWQVSWDRQQEWYMPDREQRFRTMLDMV
                     EALVGPAPRVLDLACGTGTITARLLARFPRATSTGVDLDPALLAIAEGTFAGDERVSLV
                     AADLKDPDWTARLPYGSYDAVLTATALHWLHAEPLAALYGQVAELVRDGGVLMNADHMI
                     DETTPRINEAERAQRHAQMEAAKRDGALDWAQWWQLAAKDPVLAGPTARRFEIYGEHAD
                     GDTPSAAWHARVLREKGFGEVRPVWCSPSDTLLLALK"
     gene            7371..8000
                     /locus_tag="B1H29_RS12205"
                     /old_locus_tag="B1H29_12275"
     CDS             7371..8000
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="B1H29_RS12205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12275"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_055417906.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPARGQDSLTSVEAVRELFGINQSAARR
                     ATDADVTRFRSVRGRLRSVFEAADGGDETLAVDLLNSLLLEFPVSPQISGHDHRDDDGS
                     PLWHMHLADHPSNATAGFAAIAAMGLAFHLTEYGVDRLGLCEASPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSVSTGLSADSTQRTTANGER"
     gene            complement(7904..8341)
                     /gene="sodX"
                     /locus_tag="B1H29_RS12210"
                     /old_locus_tag="B1H29_12280"
     CDS             complement(7904..8341)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925778.1"
                     /locus_tag="B1H29_RS12210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12280"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_055417907.1"
                     /transl_table=11
                     /translation="MPEQLSQESERARGALPFGPAEVTGPSMVPTLHHGDVLLVHWGAR
                     VRPGDVVVLRHPFQQDLLVVKRAVERRGTGWWVLGDNAFAGGDSTDYGVVPGELVLGRA
                     RLRYRPLRPGQRSPFAVVRWVLSALRPVLTDRSASRRLRAR"
     gene            8487..8882
                     /gene="sodN"
                     /locus_tag="B1H29_RS12215"
                     /old_locus_tag="B1H29_12285"
     CDS             8487..8882
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="B1H29_RS12215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12285"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_055417908.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVTVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAGN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKG
                     STDPATGQKALDYIAQVDKIFWETKKA"
     gene            complement(9071..9718)
                     /locus_tag="B1H29_RS12225"
                     /old_locus_tag="B1H29_12295"
     CDS             complement(9071..9718)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444621.1"
                     /locus_tag="B1H29_RS12225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12295"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_055417909.1"
                     /transl_table=11
                     /translation="MGVVIRTAGEGDRELVVRLLDEAFQDDPVSGWVFPDEEYRRRTHH
                     RLMAAFTDAVLADGRIDLTEDGAACALWLPVPADGHTGDEPGGDTGGDTGGGAEDGSVQ
                     VREAVDPDNERVELIARLTEGIHPYGRAHEYLWMIGVLPGRQGEGLGTALIEAVLERCD
                     RERLPAYLEASSARGRGLYERLGFEFTGRPLDLPDGPRMWPMWREPRTPATA"
     gene            complement(10001..11167)
                     /locus_tag="B1H29_RS12230"
                     /old_locus_tag="B1H29_12300"
     CDS             complement(10001..11167)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973720.1"
                     /locus_tag="B1H29_RS12230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12300"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_055417910.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4e-60, bitscore:
                     202.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEARHATEARRPAGTLERHGHIGTQREQGPKKPGALSDGQGPAG
                     PDGHEATVLLRESRASVDPELRSAIASLPASMRRIALYHFGWQHADGTPAGGNAGKAIR
                     PALVLTSAAALGGPGARTAAARAAAAVELVHNFTLLHDDVMDRDTTRRHRPTAWTVFGD
                     ADAILAGDALQALALRLLAADPHPASPAAAARLADCVMELCEGQHADTAMERRAPGEVT
                     LDETLAMAEAKTGALLGCACALGALYAGAAAEDVEALDAFGREAGLAFQLIDDVIGIWG
                     DPRRTGKPAGADLAARKKSLPVVAALTSGTPAAAELAELYAAPYEEGEEDLERTALAVE
                     RAGGRDWAQVQAADRMARAVQELARAVRDPEAAGGLLALAEFVTRRSA"
     gene            complement(11255..12661)
                     /locus_tag="B1H29_RS12235"
                     /old_locus_tag="B1H29_12305"
     CDS             complement(11255..12661)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="B1H29_RS12235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12305"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_055417911.1"
                     /transl_table=11
                     /translation="MSVGEEVRTEQARPQQSLGTAAARNLATTTKSVPQMQEISSRWLL
                     RTLPWVDIQGGTYRVNRRMTFAVGDGRVTFVKTGDRVEVIPAELGELPALRSYEDEEVL
                     SELAQRCEQREFGPGEVIASFGGQADEVYLLAHGKVEKVGTGPYGDDAVLGVLADGAYF
                     GDQALLDGDAIWEYTARTVTACTVLVLPRQEVEQVAERAESLRTHLEERRSIPEQRTNR
                     LGEKAIDLSAGHSGEPDIPHTFVDYDARPREYELSVAQTVLRIHSRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELVNNREFGLLHNCEYDQRIQPHDGVPGPDDLDELLSRRRGTK
                     LLLAHPRAIAAIGRELNKRGLVPETIDIAGNRIPTWRGVPIYPCNKIPVTEARTSSIIA
                     MRTGEQDQGVIGLRATGIPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWQ"
     misc_feature    complement(12729..12742)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.94"
                     /tool="antismash"
     misc_feature    12812..12827
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.67"
                     /tool="antismash"
     misc_feature    complement(12955..12968)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            12991..13569
                     /locus_tag="B1H29_RS12240"
                     /old_locus_tag="B1H29_12310"
     CDS             12991..13569
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030135.1"
                     /locus_tag="B1H29_RS12240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12310"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_055417912.1"
                     /transl_table=11
                     /translation="MSASSFLKTLKAEGLTVVQVGDWRDHNRNHKGPWGPVHGVMIHHT
                     VTKGSARTVEICRKGYEGLPGPLCHGVITKDGKVHLVGYGRANHAGLGDDDVLRAVIAE
                     KGLPRDNEANTDGNRHFYGFECENLGDGDDPWPTAQLEAIERAAAAVCRRHGWNERSVI
                     GHLEWQPGKVDPRGFTMASMRGRIRDRLK"
     gene            13606..14514
                     /locus_tag="B1H29_RS12245"
                     /old_locus_tag="B1H29_12315"
     CDS             13606..14514
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973723.1"
                     /locus_tag="B1H29_RS12245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12315"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_055417913.1"
                     /sec_met_domain="PALP (E-value: 2e-18, bitscore: 65.5,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTDTRGLAALRPRLPSPVQEVADERFGRRGVRLLLKRDDLIHP
                     ELVGNKWRKLAPNLTTADGRTVLTFGGAYSNHLRATAAAGRLLGLSTVGVVRGQELAGR
                     PLNPSLARCAADGMRLHFADRSAYRRKAEPEILAALLRAADAEGAVVVPEGGSNPEAVR
                     GCRALGEELGEHADVVALACGTGGTLAGLAAGLPPGRRTLGIPVLKGGFLADDIRRLQV
                     RAFGGLRGTWSLDDRFHHGGYARTTPELDSFAEDFEHRHGLPVERVYVAKMLHALLTLA
                     EEGAFPRGTALAAVITGRPFP"
     gene            complement(14912..16504)
                     /locus_tag="B1H29_RS12250"
                     /old_locus_tag="B1H29_12320"
     CDS             complement(14912..16504)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072182.1"
                     /locus_tag="B1H29_RS12250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12320"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_055417914.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAIAAAGRRVPVPAPLLLVAVGLAVSYVPGVP
                     DYTLDPHIVLPLLLPPLLHTAATDSSYLDLRAQVRPVALLSVGYVLFATFVVGCAAYLI
                     VPGLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLVNDATAITAFRVA
                     LAAAVGEGATWAGGIAEFLIAAIGGVGVGLVLMVPLHWLRTHVSEALLKNTLSLLIPFV
                     AYAVAEQVHASGVLAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPVVLKGLGDYEGADAAWYAVAVFLVVAVARFVWVYPATFLPRLSARVREREGDLSWK
                     VPFVIGWAGMRGVVSLAIAFSIPLTVHGGDPFPERNLILFLTFTTVIGTLVVQGVTLPP
                     LISLLKFPARDVRVETLAEANAQAQASRAAEQRLDDLLADERNALPAPLADRLRTVLER
                     RRNAVWERLGQVNPVTGETVDDTYRRLSREMISAEREVFVRLRDGRYIDDEMLRTLLRR
                     LDLEEAAAYREAA"
     gene            16567..16827
                     /locus_tag="B1H29_RS12255"
                     /old_locus_tag="B1H29_12325"
     CDS             16567..16827
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="B1H29_RS12255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12325"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_055417915.1"
                     /transl_table=11
                     /translation="MKQCTHADALPHPEPEPRGETCPECLAEGTDPVQLRLCLVCGHVG
                     CCDSSPRRHATAHHKETGHPVMRTFEPGENWRWCFVDHVLV"
     misc_feature    complement(16924..16939)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.33"
                     /tool="antismash"
     misc_feature    complement(16936..16949)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            17078..17491
                     /locus_tag="B1H29_RS12260"
                     /old_locus_tag="B1H29_12330"
     CDS             17078..17491
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985353.1"
                     /locus_tag="B1H29_RS12260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12330"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_003973726.1"
                     /transl_table=11
                     /translation="MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVSSAVDEDKTVSISLYKQRGAGPGPT"
     gene            17509..18564
                     /locus_tag="B1H29_RS12265"
                     /old_locus_tag="B1H29_12335"
     CDS             17509..18564
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136656.1"
                     /locus_tag="B1H29_RS12265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12335"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_167392528.1"
                     /transl_table=11
                     /translation="MRDEERGTRELPAEGTRSENEARRTADGIDGIPEQARPHPEDEAS
                     PEAVVPGDGERTGDAPVRPVRAEAKARERATGGTMSEHERHSEDEAPGARGTRHDPQDR
                     SGARLLFAELRTLEKDSPEYAELRNRLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIG
                     LIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLALTTATAEL
                     SQLHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLGAED
                     EALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTL
                     AQLREKLLVEE"
     gene            complement(18620..19066)
                     /locus_tag="B1H29_RS12270"
                     /old_locus_tag="B1H29_12340"
     CDS             complement(18620..19066)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326947.1"
                     /locus_tag="B1H29_RS12270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12340"
                     /product="hypothetical protein"
                     /protein_id="WP_055417916.1"
                     /transl_table=11
                     /translation="MSSEQTPTPEAAEEAGPRPGRLTAAAALAALEGLALVVGGGWMLV
                     GGLTGHPDDRTSAITGGVTLIVLALLPLLAARGLLGRRGWSRGPAVITQIMALPVAYNL
                     LQADSVAIPGGIVLGVVAVTALVLLVNPTTTQALGIRGPGSAEE"
     gene            19192..20160
                     /locus_tag="B1H29_RS12275"
                     /old_locus_tag="B1H29_12345"
     CDS             19192..20160
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134762.1"
                     /locus_tag="B1H29_RS12275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12345"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_055417917.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAAQSDDIELVVALGGDGTVNEVVNGLLHAGPDPEHLPGLAVVPGGSTNVFARALG
                     LPNHAVEATGALLDALREGSERTVGLGLASGAPGTEDEAVPARWFTFNAGLGFDAGVVG
                     RVEQHRERGKKSTHALYVRQVMRALIGEPHRRSGTITLERAGEDPITDLVLSIVSNTCP
                     WTFLGNRPIYASPKASFDTGLDVFGLSRLSTAAVARYGTQLLTSSPERGPRGRHAVSLH
                     DMTEFTLHSKVPLPLQMDGDHLGLRTSVAFTGVRRALRVIV"
     misc_feature    complement(20245..20259)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.74"
                     /tool="antismash"
     misc_feature    complement(20250..20259)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20422..20437)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20425..20436
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            20482..20739
                     /locus_tag="B1H29_RS12280"
                     /old_locus_tag="B1H29_12350"
     CDS             20482..20739
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="B1H29_RS12280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_12350"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003973730.1"
                     /transl_table=11
                     /translation="MDWRHRAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
ORIGIN
        1 gtcgatcccc agcccggcga gggcgtcggt ctcggcctgc gacagcccgg cccggcgtcg
       61 tgcctccgcg agggcccgcc ggaccgcgcc cttgcgctcg ccggccccga gcgcagacag
      121 cgcgaaggag gcacggcttc cctcgcgatc cagcagggcg agcagcagat gctcggcatc
      181 aacggtctgc gcccgcgccc cctccgcgta ctcgaccgcc ccctgcacca cgtcccgggc
      241 gtccttcgtg aaccgctcga acatcaatgc ctcccgtact tcttgtgcac ggcctgcctg
      301 ctgaccccga gttcggtggc gatctcctgc cacgaccacc cctgattgcg cgcgctgcgc
      361 acctgcaccg cctcgagctg ctccagcagc ctccgcagtg cggcgacggc ccgcagcccg
      421 acccgaggat cgcgatcacc cgcacgcgcg gcgagatccg ttgcttcact catgcggtca
      481 acataggttg acagcctcga gcatgtcaac ccccgttgac atcctggctg ccgtacgggg
      541 aacgcgaacg gcgggcccgg acgaccgggc ccgccgtaga cgctctggac ggttcggggg
      601 aacgcgtcag gaaccgctga gcacgatctt gccgaactgc tccccggagg ccatccgctc
      661 gaacccctcg cgggcccggt ccatcggaag cacctcgtcg atgacgggac gcacacccgt
      721 cgcggcgcag aaggacagca ggtcctccag ctcgtccttg gtgcccatcg tggagccgac
      781 gatcctgagc tccaggaaga agacccgggt gagctcggca tgggagggcc ggtcgccgct
      841 ggtggcgccg gagatgacga gcgtgccacc cggccgcagc gacttcaccg agtgggacca
      901 ggtggcggcg cccacggtct cgatgacggc atcgacccgc cgcgacagcc gcgcgcccgg
      961 ctcgacggcc tccacggcgc ccagctccag ggcccgcttg cgcttggcct cgtcccggct
     1021 ggtggcgaag acacgcagtc cggccgcctt gccgagcacg atcgcggccg tggcgacccc
     1081 accgccggcg ccctgcacca gcaccgagtc acccggacgc accccggcgt tggtgaacag
     1141 catccggtac gccgtcagcc aggcggtcgg cagacaggcc gcctcctcga aggagagctc
     1201 cttaggcttg ggcaggatgt tccaggtcgg cacggcgacc cgctcggcga acgttcccgg
     1261 atagcgctcg gtgaggatgg agcggggctc cttgggaccg accccgtgtc cggtctggcc
     1321 gatcacggag tgcaggacga cctcgttgcc gtcctcgtcg acaccggcgg cgtcacagcc
     1381 gaggatcatc ggcagccggt cctcggggag gccgacgccg cgcagggacc acaggtcgtg
     1441 gtggttgagg gaggcggccc tgacatcgac gacactccag ccggggcggg cctcgggagc
     1501 gggacgctct cccaactcga ggccggtcag cggctggtcg cggtcgatgc gggcggcgta
     1561 gacagcgaac atgaccttga cgataggttc cccacccgcc atccggaacc gtacgcccct
     1621 gtgacacacg ccctcttgtc accgcggccg gccgctcccg gcaaaggtgc gggcatcgcg
     1681 cccccacgcg tgaccggaag accccggcca ctcccggccg cccacccgcc ccgcacaccc
     1741 acgtcacgtc ccgagcccgc gagaacgcgg tccgcgaaag cagacggccc cgtccaccga
     1801 ggacgaggcc gttcacccca cgcggagtca caccgtcacc ggcgcgcgac cccctccgcc
     1861 cgagccgccg ccgccaccgc ggccgtgacg gccggcgcga cgcgctcgtc gaacggggac
     1921 gggatgacgt agtccgcggc gaggtcgtcg cccaccaccg aggccagcgc ctcggccgcc
     1981 gcgagcttca taccctcggt gatccgggac gcccgcacct gcagcgcgcc cgcgaagatg
     2041 cccgggaacg ccagcacgtt gttgatctgg ttcgggaagt ccgaccgccc cgtcgcgacg
     2101 accgccgcgt acttgtgggc gacctccggg tgcacctcgg ggttcgggtt ggccatcgcg
     2161 aagacgaacg cgcccttcgc catcgaggcg accgccggct ccggcaccgt accgccggag
     2221 acgccgatga agacgtcggc gccggacagg gccgcctcca gcgagccgga cagccccgcc
     2281 ttgttggtga aggaggccac ttcccgcttg accggggtca ggtcgtcccg gtcggccgag
     2341 acgacgccct tgcggtcggc caccgcgacg tccccgatgc cggcctcgac cagcatcttg
     2401 gcgatggcga caccggccgc gcccgcaccc gagatcaccg cccgcagctc acccagcgtc
     2461 cgcccgctca gccgcgcggc gttccgcagg gccgccagcg tcacgaccgc cgtgccgtgc
     2521 tggtcgtcgt ggaagaccgg gatgtccagg cgctcctgga gcttgcgctc gatctcgaag
     2581 caccgcggcg ccgagatgtc ctccaggttc acgccaccga aggagggcgc gagccgcacc
     2641 accgtctcga cgatctcgtc ggcgtccgtg cagttcagcg cgatcggaac cgcgtccaca
     2701 ccgccgaact gcttgaacag gatcgccttc ccttccatca ccggaagaga ggcctcgggc
     2761 ccgatgtccc cgagccccag aacggccgta ccgtccgtca cgaccgccac gaccgacgac
     2821 ttccacgtgt agtcgtgcac gaggtcgggc tgctcggcga tcgcgctgca cactttcgcg
     2881 acgccgggcg tgtacgccag ggacaggtcg tccttgtcac ggaccggcac ggtggcctgc
     2941 acggccatct tgccgccgcg gtgcagcgcg aacgcggggt cgaaggagtc gaggggctcg
     3001 gcgcccgcct cctgctccgc actggcgccg ctgtcgctgc gaggattgac gatctccgct
     3061 gccactttgt cttacccctt aagagttcat ggtttgaggg tttgtccact cctggtgagg
     3121 aatgggcggg caccgcgcag gaagatggct gtctgggcca cacggacccc tgcgcgacgg
     3181 gcgcgccgca cacgcgccct gagcccctga tgaggggtgt aaagaacctt cttacccgac
     3241 ggacaccccc cgcgacgagt ccgataagtg caagctcaca tgtcggaccc cggacgccgc
     3301 atgtcggtga catggctcat acccagtgat ccggacaact tctcgccgcc ccttgacagg
     3361 cctggagaac acgccttcag cagccgcgcg cgccggtgaa ccatgcccac atatcgagaa
     3421 atgccgaaga tctttcggcc ggaagggccg attcccgtaa aggttcggtc gtgatgtacc
     3481 gacctggtgc ggttcgggcg gtgacccgtt atccgatttt gacatggcgt cccccctgaa
     3541 tggccgagtc cgaatggcaa gatgccgtaa tcacacgagg tcgcgacact cgaaggcgtg
     3601 tgctctcgtc gacccacggc gcctgccggt acccggccgg cgtcccgtcc caccggaagt
     3661 ccaccgcccc catcggcaac tcccttcacc gccggaggaa ccaccatgac cgcaagctcc
     3721 acccgtcgta cgaccgccgc gcactcccgg atagcagcgg tcggtgcgat cgcggtcgca
     3781 ggcgctctgc tgctcaccgg atgcggcgac cagaccgaga gcagcgactc cggcagcagc
     3841 gacaaccagt ccgcggcggg cgcccccctg gccgaccggc tcccgcagtc catccgtgac
     3901 aagggcgtca tcaaggtcgg ctccgacatc gcctacgccc cggtcgagtt caaggacaag
     3961 tccggcaaga cggtcggcat cgacccagat ctcgcggacg ccatgggcaa gcagctcggg
     4021 gtgaagttcg agttcgagaa cggcaccttc gacaccctga tcaccggtct gcgctccaag
     4081 cgctacgaca tcgccatgtc ggcgatgacc gacaccaagg accgccagga gggcatcgac
     4141 tcggacaccg gcaagaaggt cggccagggc gtcgacttcg tggactactt caccgccggt
     4201 gtctcgatct acaccaagaa gggcgacgac cagggcatca agacctgggc cgacctctgc
     4261 ggcaagaagc tcgtgctcca gcgcggcacg gtctcggagg acctcgccaa ggccgagaac
     4321 gagaagtgcc cggcgggcaa gaagatctcc atgcagccct tcgacaacga ccagcaggcc
     4381 cagacccgcc tgcgcgcggg cggcgccgac gccggttcgt ccgacttccc ggtcgcggcg
     4441 tacgcggtga agacctccgg cggcggcgac gacttccaga tcgtcggcga gcaggtcgag
     4501 gccgcgccgt acggcatcgc ggtcgccaag gacaacacga agctgcggga cgccctgaag
     4561 gcggcgatgg acgcggtgat cgcgaacggc gagtacaaga aggtcctcga caagtggggc
     4621 gtcgcggaag gcgccgtcac ggaggccacc atcaacggcg gcaagtgacc gcgcggcggg
     4681 cactgaaagg caacatccgt gactgttgac atcgacaaga cggcgggcgg cccggccgac
     4741 accccgccgg ccggaccgga ggccatcaag gccatcccgg tccggcacta cgggcggtac
     4801 gtctccgcgg tcgtcgcgat cgcgctgctg gccgcggtcg tctacgcgtt ctcccagggc
     4861 aagatcaact ggggtgcgat cccggactac ttcttcgacg accgcgtcct gaccggcatg
     4921 ggcaagacgc tcctgatcac cgtcctcgcg atgctgatcg gcgtcttcgg cggcatcctg
     4981 ctcgccgtga tgcggctgtc gaagaacccg gtgacctcgt ccatcgcgtg gttctacatc
     5041 tggttcttcc gcggcacgcc cgtcctggtg cagctcgtcg tctggttcaa cctgggcctg
     5101 gtcttcgagt acatcaacct cggcccgttc taccgcgacg agtggtcgga cttcatgacg
     5161 ccgttcctga cggcgctgct cggtctcggt ctcaacgagg ccgcgtacat ggcggagatc
     5221 tgccgcgccg gtctgctggc ggtcgacgag ggccagaccg aggcggccca cgcgctcggc
     5281 atgagccaca ccaagacgct gcgccggatc gtggtcccgc aggcgatgcg cgtgatcgtg
     5341 ccgccgacgg gcaacgaggt catcaacatg ctgaagacga cctcgctggt gtcggtcgtc
     5401 cagtacgccg agttgttccg ggtcgcccag gacatcggcc agacctccgg cgcgccggcc
     5461 gagatgctgt tcctggccgc ggcctggtac ctgctgctga cttcggtctt cagcgtcggc
     5521 cagtactacc tggagcgcta ctacgcgcgc ggctccagcc gcagcctgcc gaagaccccg
     5581 atgcagaaga tcagggcgaa cctgctgtcc ctgtcgaacc gctccagcac gacgggaggc
     5641 gcggcatgac cgccatggtg aaggccgagg gcgtccacaa gtccttcggc gcggtcgagg
     5701 tcctcaaggg catcgacctg gaggtgaagc agggcgaggt gttctgcctc atcggcccct
     5761 ccggctccgg caagtcgacc ttcctgcgct gcatcaacca cctggagaag atcaacgccg
     5821 ggcggctgta cgtcgacggc gagctggtcg gctaccgcca gaagggcgac aagctctacg
     5881 agctcaagga cagcgaggtc gccgtcaagc ggcgggacat cggcatggtc ttccagcgct
     5941 tcaacctgtt cccgcacatg acggccctgg agaacgtcat ggaggcgccg gtgcaggtca
     6001 agggcgtgag caaggcccag gccagggacc gcgcgcgcca gctcctggag cgggtgggcc
     6061 tgggcgacaa ggccggcaac tacccctcgc agctctccgg cggccagcag cagcgcgtcg
     6121 ccatcgcacg ggccctcgcc atggacccga agctgatgct gttcgacgag ccgacctcgg
     6181 cgctcgaccc cgagctggtc ggcgacgtcc tcgacgtcat gcgcgacctc gccgagtccg
     6241 gcatgacgat ggtcgtcgtc acccacgaga tgggcttcgc ccgggaggtc ggcgacagcc
     6301 tggtcttcat ggacgacggc gtggtggtcg agtcgggcaa cccgcgcgac gtcctgaccg
     6361 acccgcagca cgagcggacg aaggcgttcc tgtccaaggt cctctgaacg cccgcgaggc
     6421 ggcggaccgc acgacgacag gccgaggggc ggtacggaga tccgtaccgc cccttcgggc
     6481 tgctcccggg ctacttgagg gccagcagca gcgtgtccga cggcgagcac cacaccggcc
     6541 gcacctcgcc gaatcccttc tcgcgcagca cgcgcgcgtg ccacgccgcc gagggcgtgt
     6601 caccgtcggc gtgctcgccg tagatctcga agcggcgggc cgtgggcccg gcgaggaccg
     6661 ggtccttggc ggcgagctgc caccattggg cccagtcgag cgcgccgtcg cgcttggccg
     6721 cctccatctg cgcgtgccgc tgggcgcgct cggcctcgtt gatccgtggc gtcgtctcgt
     6781 cgatcatgtg atccgcgttc atgaggacac caccgtcgcg gaccagttcc gcgacctgac
     6841 cgtagagggc cgcgaggggt tcggcgtgga gccagtgcag ggccgtggcg gtcaggacgg
     6901 cgtcgtagga gccgtaaggc agtcgcgccg tccagtcggg gtccttcagg tcggcggcga
     6961 ccagggagac tcgttcgtca cccgcgaagg tgccctcggc gatggccagg agcgccgggt
     7021 cgaggtccac gccggtgctg gtggccctgg ggaaccgggc gagcagccgg gcggtgatgg
     7081 tcccggtgcc gcaggcgagg tcgagcaccc gcggcgcggg gccgaccagg gcctcgacca
     7141 tgtccagcat ggtccggaag cgttgctcgc ggtccggcat gtaccactcc tgctgccggt
     7201 cccagctcac ctgccaggcc cgccagtcag cggcggtcgt gatggtagtg gtggtgtccg
     7261 cgtccgtcat cgagcccctc cgtcgcgtac gagacgtaat accctggaag cacgatcagc
     7321 cgttacctga tcgcaggcac gaccatagag ccccttcgta aggactacaa gtggaactgg
     7381 cctattactc ggattacgcc gtacgtctcg tcaacaccga ggaaccggcc cgggggcagg
     7441 actcactgac ctcggtcgag gccgtccgcg agctcttcgg catcaaccag tcggcggccc
     7501 ggcgcgcgac ggacgcggac gtgacccggt tccgttcggt gcggggacgg ctgcgctcgg
     7561 tcttcgaggc ggccgacggc ggcgacgaga cgcttgccgt ggacctcctc aactccctcc
     7621 tgctggagtt cccggtgagc ccgcagatct ccggccacga ccaccgcgac gacgacggca
     7681 gcccgctgtg gcacatgcac ctggcggatc atccgtccaa cgcgacggcc ggtttcgccg
     7741 ccatcgcggc gatgggcctg gccttccacc tcaccgagta cggcgtggac cgcctgggcc
     7801 tgtgcgaggc ctccccctgc cgcaacgcct acctggacac ctccaccaac cgctcccggc
     7861 ggtactgctc cgaccgctgc gccacccgtg ccaacgtggc ggcctaccgc gcccgcaagc
     7921 gcctggaggc ggaccggtcg gtcagcaccg gcctgagcgc cgacagcacc cagcggacca
     7981 cggcgaacgg cgagcgctga cccggcctga gcggccggta ccgcagccgc gccctgccga
     8041 gcacgagctc cccggggacc accccgtagt cggtgctgtc cccgcccgcg aacgcgttgt
     8101 cccccagtac ccaccagccg gtcccgcgcc gctcgacggc gcgtttgacc acgaggaggt
     8161 cctgctggaa gggatgcctc agcacgacca cgtcaccggg ccgcaccctg gccccccagt
     8221 gcaccaggag cacgtccccg tggtgcagcg tgggcaccat ggacggcccg gtcacctcgg
     8281 ccggcccgaa gggcagggcc cctctcgcac gttcgctctc ctgcgacaac tgctccggca
     8341 tgacccggca cctccccggt ctttcctcca ccagtctcag tctcaccccg gacttttgtc
     8401 ctaagcccac gggggcactc gcgaaatcgg gcctcccagg gagtaatgtc ccccctgaga
     8461 agacgatcac gaggaaggaa cgctccatgc tttcccgcct gtttgccccc aaggtcacgg
     8521 tcagcgccca ctgcgacctg ccctgcggcg tgtacgaccc ggcccaggcc cgcatcgagg
     8581 cggagtccgt gaaggccgtc caggaaaaga tggccggtaa cgacgacccg cacttccagg
     8641 ctcgcgccac ggtcatcaag gagcagcgcg ccgagctcgc gaagcaccac gtctccgtgc
     8701 tgtggagcga ctacttcaag cccccgcact tcgagaagta cccggagctg caccagctcg
     8761 tcaacgacac cctgaaggcc ctgtcggccg ccaagggttc gaccgacccg gcgaccggcc
     8821 agaaggccct ggactacatc gcccaggtcg acaagatctt ctgggagacc aagaaggcct
     8881 gatcttcgat cccgccgttt gacctgcgct ttccctggtc gctgggtctt ccggtccgca
     8941 cccggcccgc ggtacgccga gcacggcgtc cctgacggac cgggtgcggc cttctttcac
     9001 cgcctcctgc acggactcgc ggacccggaa gccggcctgg acgcccggtt cacgtagcag
     9061 cgcgtcgcgg tcaggcggtc gccggtgtcc ggggttcgcg ccacatcggc cacatccggg
     9121 ggccgtccgg caggtccagg ggccggccgg tgaactcgaa gccgaggcgc tcgtacagcc
     9181 cccggccgcg ggcactgctg gcctccaggt acgcgggcag ccgctcgcgg tcgcagcgtt
     9241 ccaggaccgc ttcgatgagc gcggtgccca ggccctcgcc ctgccgtccg ggcaggacgc
     9301 cgatcatcca caggtactcg tgggcccggc cgtacgggtg gatgccctcc gtcagccggg
     9361 ctatcagctc gactcgctcg ttgtccgggt cgaccgcctc gcgcacctgg acggagccgt
     9421 cctcggcccc gccgccggtg tcaccgccgg tgtcaccgcc gggctcgtcg ccggtgtgcc
     9481 cgtccgccgg cacgggcagc cacagggcgc aggccgcgcc gtcctcggtg agatcgatgc
     9541 gcccgtcggc cagcacggcg tcggtgaagg ccgccatgag ccgatggtgc gtccggcggc
     9601 ggtactcctc gtcgggaaag acccagccgc tcaccggatc gtcctggaag gcctcgtcca
     9661 gcagccgcac gaccagctcc cggtcgccct cccccgccgt ccggatcacc acacccatgt
     9721 cccgcccgcc ccttcggctc aacaccgctc gtccgtacgg cggttgagcc tagccgcaga
     9781 tgccggcgga ggcgggcgcc ggtcggcggc ccccggccgt acggccgtac accggaaggg
     9841 ggcgggcccc gcacaccgtg gggaagtgcg ggacccgccg aaccggagcc ctcggcggtg
     9901 cggccgtacg tcggtcaggt ccgtacggtc ctgcacgggc tccggggtct tgcgcggccg
     9961 gccgggcgtc gcgcgctcgc cgggccggcc agggtggccg tcaggcgctg cgccgggtca
    10021 cgaactcggc cagcgcgagc aggccgcccg ccgcctccgg gtcgcgcacg gcccgggcca
    10081 gctcctgtac ggcccgggcc atccggtcgg ccgcctggac ctgcgcccag tcccggccac
    10141 ccgcccgctc cacggccagt gcggtgcgct ccaggtcctc ctcgccctcc tcgtacggcg
    10201 ccgcgtacaa ctcggcgagt tcggcggcgg ccggggtgcc ggaggtgagg gcggcgacca
    10261 ccggcagcga cttcttgcgg gcggccaggt ccgcgccggc cggcttgccg gtacggcgcg
    10321 ggtcgcccca tatgccgatg acgtcgtcga tgagctggaa ggcgaggccc gcctcgcggc
    10381 cgaaggcgtc cagggcctcg acgtcctcgg cggcggctcc ggcgtacagc gcgccgaggg
    10441 cgcaggcgca tcccagcagg gcgccggtct tggcctcggc catggcgagc gtctcgtcga
    10501 gggtgacctc gcccggggcg cgccgctcca tggccgtgtc cgcgtgctgg ccctcgcaga
    10561 gttccatgac gcagtcggcg agccgggcgg cggccgccgg cgacgccggg tgggggtcgg
    10621 cggcgagcag ccgcagggcc agcgcctgga gggcgtcccc ggcgaggatc gcgtcggcgt
    10681 cgccgaacac ggtccacgcg gtggggcggt ggcgccgggt ggtgtcacgg tccatcacgt
    10741 cgtcgtgcag caacgtgaag ttgtggacca gctccaccgc cgccgcggcc cgcgccgccg
    10801 ccgtccgcgc cccgggtccg ccgagcgcgg cggccgaggt gaggacgagc gccgggcgga
    10861 tcgccttgcc cgcgttgccc cccgcgggcg tgccgtccgc gtgctgccag ccgaagtggt
    10921 agagcgcgat ccggcgcatc gaggcgggca gtgacgcgat ggcggagcgc agttcggggt
    10981 cgaccgacgc ccgggactcc cgcaggagca ccgtcgcctc gtgtccgtcg ggccccgccg
    11041 gcccctgccc gtcggacaac gcccccggct tcttcggccc ctgctcccgc tgcgtgccga
    11101 tgtgcccgtg cctttccagc gtcccggcgg ggcgacgcgc ctcggtggcg tgccgagcct
    11161 ctgtcatgga ctcacctccc ccattcgccc gtctccgcac ccccggggtg tacccgcccg
    11221 ggagggcggg gacacggcgt tcgggagacc ggcgtcactg ccagcggccg atctcgacgt
    11281 tctccaggac gccgagcgcg tcgggtacga ggaccgcggc cgagtagtag gccgtgacca
    11341 ggtacttgat gatggcctgc tcgttgatgc ccatgaaacg caccgacaga ctcggctcga
    11401 tctcgtcggg gattccggtg gcacggaggc cgatgacgcc ctggtcctgt tcgccggtgc
    11461 gcatcgcgat gatcgaggac gtacgggcct cggtgaccgg gatcttgttg caggggtaga
    11521 tcggcacacc ccgccaggtc gggatgcggt tgcccgcgat gtcgatcgtc tcggggacga
    11581 gcccgcgctt gttgagctcc cggccgatcg cggcgatcgc gcgcgggtgg gcgaggagca
    11641 gcttggtgcc gcggcggcgg ctcagcagct cgtccaggtc gtccgggccc ggcacgccgt
    11701 cgtgcggctg gatccgctgg tcgtactcgc agttgtgcag caggccgaac tcgcggttgt
    11761 tgacgagctc gtgctcctga cgttctttca gcgcctcgac cgtcagccgg agctgctgct
    11821 cggtctggtt catcggctgg ttgtagagat cggccacgcg ggagtggatg cgcagcacgg
    11881 tctgggcgac gctcagttcg tactcgcggg gccgggcgtc gtagtcgacg aaggtgtgcg
    11941 ggatgtccgg ctcgccgctg tgaccggcgg agaggtcgat cgccttctcg ccgagccggt
    12001 tggtgcgctg ctccgggatc gagcgccgct cctcgaggtg cgtgcgcagt gattccgcgc
    12061 gctccgcgac ctgctccacc tcctggcggg gcagcacgag caccgtgcag gcggtgacgg
    12121 tgcgggcggt gtactcccag atggcgtccc cgtcgagcag cgcctggtca ccgaagtagg
    12181 cgccgtcggc caggaccccg agcaccgcgt cgtcgccgta ggggccggtg ccgaccttct
    12241 ccaccttgcc gtgcgccagc aggtagacct cgtcggcctg gccgccgaac gaggcgatca
    12301 cctcgcccgg gccgaactca cgctgctcac agcgctgcgc gagttccgag agcacctcct
    12361 cgtcctcgta cgaccgcagg gccggcagct cgcccagttc ggcggggatg acctcgaccc
    12421 ggtcgccggt cttcacgaac gtcacccggc cgtcgccgac ggcgaaggtc atgcgccggt
    12481 tcacccggta cgtgccgccc tggatgtcca cccacggaag cgtgcgcagc agccagcggg
    12541 agctgatctc ctgcatctga ggaacggact tggtcgtggt ggccaggttc cgcgcggccg
    12601 ccgtgccaag actctgctgc ggcctggcct gctcggtgcg gacctcttcg cctaccgaca
    12661 taaggaattg ccctcccggt catgccggac ggctgcgccc ggcatcgatg tgcgtgaacc
    12721 agccttcctc acggagagtg ccggtgctat tacccgaaag agcgggaatg gatcaacgat
    12781 gaccggggca gagaggggca gcccgttcgg gttcgcggtt tcttgtcggt atctgttcaa
    12841 aactgtcggt cgggacgggg ttgtccggat cggatcgcac acggaccgaa caggtactag
    12901 cgagcactcc gcttaggtac aagctcccta cgaggcgaac gcgccgggcg gtcgtcgcgc
    12961 agcgtgaagg agtcggccgt ggcgtcaccc atgtccgcga gcagtttcct caagacactg
    13021 aaggcggagg gcctcaccgt cgtccaggtc ggcgactggc gggaccacaa ccgcaatcac
    13081 aaaggtccct ggggacccgt gcacggcgtg atgatccacc acacggtcac caagggcagc
    13141 gcgcggaccg tggagatctg ccgcaagggt tacgaaggcc tgccggggcc actgtgccac
    13201 ggggtcatca ccaaggacgg caaggtccac ctggtcgggt acggccgggc caaccacgcc
    13261 gggctcggtg acgacgacgt gctgcgcgcg gtgatcgcgg agaaggggct gccccgggac
    13321 aacgaggcga acaccgacgg caaccggcac ttctacggct tcgagtgcga gaacctgggc
    13381 gacggcgacg atccctggcc gacggcgcag ttggaggcga tcgagcgggc cgccgccgcg
    13441 gtctgccgcc gccacgggtg gaacgaacga tccgtcatcg gccacctcga atggcagccg
    13501 gggaaggtcg atccgcgggg gttcacgatg gcgtcgatgc ggggacggat ccgggaccgg
    13561 ctgaagtgac gtgtccgctg tgcgccgcgg cgtgacaatg gcggggtgac cggcaccgac
    13621 acccgcggcc tcgccgccct gcgcccccgc ctgccctctc ctgtgcagga ggtcgccgac
    13681 gagcggttcg gacgtcgcgg tgtccgcctg ctgctgaagc gggacgatct catccacccc
    13741 gagctggtcg gcaacaaatg gcgcaaactc gcaccgaatc tcaccacggc ggacggccgt
    13801 accgtcctca cgttcggtgg cgcctactcc aaccacctgc gcgccacggc cgccgccggc
    13861 cggctgctcg gcctgtccac cgtgggcgtg gtccgcggcc aggaactggc cggccggccg
    13921 ctcaatccct cgctggcccg gtgcgcggcc gacggcatgc ggctgcactt cgccgaccgc
    13981 tcggcgtacc gccgcaaggc cgaaccggag atcctggcgg ccctcctgcg tgcggcggac
    14041 gccgagggcg cggtcgtcgt ccccgagggc ggcagcaacc cggaggcagt ccgcggctgc
    14101 cgggccctcg gcgaggagct gggcgagcac gccgacgtgg tcgcgctcgc ctgcggcacc
    14161 ggcggcacgc tcgccgggct ggccgccggc ctcccgccgg gccgccggac gctcgggata
    14221 cccgtcctca agggcggctt cctggccgac gacatacggc ggctccaggt ccgtgccttc
    14281 ggcgggctcc gcggcacctg gagcctcgac gaccgcttcc accacggcgg ctacgcccgc
    14341 accactccgg agctcgactc cttcgccgaa gacttcgaac accgccacgg cctccccgtg
    14401 gagcgcgtct acgtcgccaa gatgctccac gccctgctca cgctcgccga ggagggcgcc
    14461 ttcccgcgtg gcacggccct ggcggccgtc atcaccggcc gccccttccc ctgagcggac
    14521 gacggacccc gccaggcgtc gggggcgccg cagggcctcg tggtcccgcg tgcggtacac
    14581 cgccgaaccg gccgccgccg gccttcggcc ccggcgcacc cggcccccgg ccggcccacg
    14641 accggcgggt cccggcgccc tcgcggagtg ggacgcctac ccgaccgcga ggccgcccgg
    14701 cgcgttcggg cggcctcgcg gtccccggac ggccgggact cccgacacgc tctgcggctc
    14761 caacggcctc accgacgcgt gcgcacgcct ccgcgccctg gagcacaggg cccgccccgc
    14821 gcgttcgggc gaggccggtt cggtctacgg gcgggcgacg ggccctcgca ccgttcccct
    14881 cgcccggcac ctcacgcgcg cgtgggcgcc gctacgccgc ctcccggtat gccgccgcct
    14941 cctccaggtc cagtcggcgc agcagcgtcc ggagcatctc gtcgtcgatg tagcggccgt
    15001 cccggagccg gacgaagacc tcgcgttcgg cgctgatcat ctcccgcgac agccgccggt
    15061 aggtgtcgtc gacggtctcc ccggtgacgg ggttgacctg tccgagccgt tcccagacgg
    15121 cgttgcggcg ccgctccagc accgtgcgga ggcggtcggc gagcggggcc ggcagggcgt
    15181 tgcgctcgtc ggcgaggagg tcgtccaggc gctgctcggc cgcccgggag gcctgcgcct
    15241 gcgcgttggc ctccgcgagc gtctcgaccc gtacgtcgcg cgcggggaac ttcagcaggc
    15301 tgatcagcgg cggcagggtg acgccctgga cgacgagtgt cccgatgacc gtggtgaagg
    15361 tgaggaacag gatgaggttg cgctcgggga agggatcgcc gccgtgcacg gtgagcggga
    15421 tggagaaggc gatcgccagc gacaccacgc cccgcatacc ggcccagccg atcacgaacg
    15481 gcaccttcca ggagaggtcg ccctcacgct cgcgtacgcg tgccgacaag cgcggcagga
    15541 aggtcgccgg atacacccac acgaacctcg ccacggcgac gaccaggaag acggcgaccg
    15601 cgtaccaggc cgcgtcggcg ccctcgtagt caccgaggcc cttgaggacg acgggcaact
    15661 ggaggccgat cagggcgaac acggccgact ccaggacgaa cgcgaccatc ttccacaccg
    15721 cctcctcctg gagacgggtg gcgaaatcga cctcccacgc gcggtggccg agatagagcg
    15781 cgacgaccac gaccgcgagc accccggagg cgtgcacctg ctcggcgacc gcgtaggcga
    15841 cgaacgggat cagcagggag agcgtgttct tgagcagcgc ctcgctcacg tgcgtgcgca
    15901 gccagtgcag cggcaccatc agcaccagcc cgacaccgac accgccgatg gccgcgatca
    15961 ggaactccgc gatcccgccg gcccacgtgg cgccctcgcc gaccgccgcg gcgagcgcca
    16021 ccctgaaggc ggtgatggcg gtggcgtcgt tcaccaggga ctcgccctgg aggatcgtgg
    16081 tgatgcgaga gggcagcccc acgcggcgcg cgaccgccgt ggccgcgacg gcgtccggcg
    16141 gcgccaccac cgcgccgagc accagggccg cggtcagcgg caggcccggc acgatcaggt
    16201 acgcggcgca gccgacgacg aaggtggcga acaggacgta gcccacggac agcagcgcca
    16261 cgggccgcac ctgtgcccgc agatcgaggt aggagctgtc ggtggccgcc gtgtggagca
    16321 gcgggggcag cagcaggggc aggacgatgt gcgggtcgag ggtgtagtcc ggcactccgg
    16381 ggacataact caccgccagc cccaccgcga ccagcagcag cggcgccggc accggcacgc
    16441 gccggcccgc cgcggcgatc gcggcgctgc ccgccaccag cagcagcagc ggcatcacgt
    16501 ccatcgtcct cgcccgccct cgtttttccg cgcggtgatc cgcacacccg tcgtaacctg
    16561 gcaatcatga aacagtgcac gcacgccgac gcgctgccgc acccggaacc ggaaccgcgc
    16621 ggcgagacct gcccggagtg tctggccgag ggcacggatc cggtacagct ccggctgtgc
    16681 ctcgtctgcg gtcacgtcgg ctgctgcgac tcctcgccga ggcggcacgc gacggcgcac
    16741 cacaaggaga cgggccaccc tgtgatgcgc accttcgagc ccggggagaa ctggcgctgg
    16801 tgcttcgtcg accacgtcct cgtgtgacct ctgcccggga cggttcgacc gtctgaggcc
    16861 tgggtacgtc aacccggcgc gcgctcttcc gatttgggcc cgccgaaccc ctagccactg
    16921 tgtgtgttca tgtgtttact atgagtgaca gcaaggggtt ggggtctcgg ggacaggaaa
    16981 gttcggagcg cgataacgtc accgctgaac cacgtatcgc gttatcccga ggggcgaccc
    17041 tcggccctgt aacgcttgta ccaccttgga ggtgagggtg tcccagatcg caggcgagcc
    17101 cgcgacccag gacttcgtcg aagtccggct gccggccgcg ggtgcctacc tgtcggtgct
    17161 gcgtacggcg acggccggcc tcgcagcccg cttggacttc accctcgacg agatcgagga
    17221 cctgcgcatc gcagtcgacg aggcctgcgc gatcctgctt cagcaggccg tgcccggctc
    17281 ggtgctcagt tgtgtcttcc gcctcgtcga cgactcgctc gaggtcactg tctcggcgcc
    17341 gaccacggac ggccacgccc cgtcgcggga caccttcgcc tggaccgtgc tgtccgccct
    17401 cgcgggcaag gtgtcctccg ccgtggacga ggacaaaacc gtttcgatca gcctctacaa
    17461 acagcgcggc gcgggacccg ggccgacgtg aggaacgggg acgggccggt gcgggacgaa
    17521 gagcgcggca cacgggagct gccggccgag ggcacacgtt ctgagaacga ggcccggcgc
    17581 acggcggacg gcatcgacgg catccccgag caggcccggc cgcatccgga ggacgaggcc
    17641 tcccccgagg ccgtcgtccc gggcgacgga gagcggaccg gggacgcccc cgtccggccc
    17701 gtccgagcgg aggcgaaggc tcgggaaagg gcaacgggcg ggacgatgag cgagcacgag
    17761 cgacactccg aggacgaagc gccgggtgca cggggcacgc ggcacgaccc gcaggaccgc
    17821 agcggggcgc gcctcctgtt cgccgagctg cgcacgctgg agaaggacag ccccgagtac
    17881 gcggagctgc gcaaccggct ggtccgcatg cacctgccac tcgtcgagca cctcgcgcgc
    17941 cgcttccgca accgcggcga gcccctggac gacctcaccc aggtcgccac catcggactg
    18001 atcaagtccg tcgaccgctt cgatccggac cgcggggtgg agttctccac gtacgcgacc
    18061 ccgaccgtcg tcggcgagat caagcggcac ttccgggaca agggctgggc ggtgcgcgtc
    18121 ccgcggcgcc tgcaggagct ccgcctggcg ctgacgacgg ccacggcgga actctcgcag
    18181 ttgcacgggc gctcccccac ggtccacgag ctcgccgaga agctggcgat ctcggaggag
    18241 gaggtcctgg agggcctgga gtcggccaac gcgtactcca cgctgtccct ggacgtcccg
    18301 gacaccgacg acgagtcccc ggcggtcgcg gacaccctgg gcgccgagga cgaggccctg
    18361 gagggcgtcg agtaccggga gtccctcaag ccgctgctgg aggaccttcc gccgcgggag
    18421 aagcggatcc tgctgctgcg cttcttcggc aacatgaccc agtcgcagat cgcgcaggag
    18481 gtcgggatct cccagatgca cgtgtcgcgg ctgctggccc gcacgctggc acagctacgg
    18541 gagaagctgc tggtcgagga gtagccgccg gacaccggcc ggtggtcgct cacgccacgg
    18601 ccggagcacc gggcggcgct tactcctcgg cgctgccggg cccccggatg ccgagggcct
    18661 gggtggtcgt ggggttcacg agcagcacca gcgccgtgac ggcgacgacg ccgagcacga
    18721 tgcctcccgg gatggccacg ctgtccgcct gcagcaggtt gtaggccacg ggcagcgcca
    18781 tgatctgcgt gatgacggcg ggcccccggc tccatccccg ccggccgagc agtccacggg
    18841 cggcgagcag cggcagcagg gcgaggacga tcagggtgac gccgccggtg atggccgagg
    18901 tccggtcgtc ggggtggccg gtgaggcctc ccacgagcat ccagccgccg ccgacgacca
    18961 gcgccagccc ctccagtgcg gccagcgcgg ccgcggcggt cagcctgccg ggacgggggc
    19021 ccgcctcttc ggcggcttcg ggggtggggg tctgctcact gctcacccct gcagggtagc
    19081 cctcggcgca ccggcgcccg cgggcgcgtc cggcggaccg cgcgccgtgc gcccgcggtg
    19141 atctccacct cggtctgggc cgggtaccac tcagtaggta ccctgcaaac catgcgtgca
    19201 cttctcgtgg tcaatccggc ggcaaccacc acgagtgcgc gcacgcgcga cgtgctgatc
    19261 cacgcgctcg cgagcgagat gaagctggag gcggtcacca ccgagtaccg cggccacgcg
    19321 cgcgacctcg gccggcaggc ggcgcagagc gacgacatcg agctggtggt ggccctcggc
    19381 ggcgacggca cggtgaacga ggtcgtcaac ggcctgctgc acgccggtcc cgacccggag
    19441 cacctgcctg gcctcgcggt ggtccccggc ggttccacca acgtcttcgc ccgcgccctc
    19501 ggcctgccca accacgcggt ggaggccacc ggcgccctgc tggacgcgct gcgcgagggc
    19561 agcgagcgga ccgtcggact gggcctggcc tcgggtgcgc cgggcaccga ggacgaggcg
    19621 gtcccggccc gctggttcac cttcaacgcc gggctgggtt tcgacgccgg cgtggtcggc
    19681 cgggtcgagc agcaccgtga gcgcgggaag aagtcgacgc acgccctcta tgtccgccag
    19741 gtgatgcgcg cgctcatcgg cgagccgcac cgccgcagcg ggacgatcac cctggagcgg
    19801 gcgggcgagg atccgatcac cgatctggtg ctgtccatag tctcgaacac gtgcccctgg
    19861 acgtttctcg gcaatcgccc gatctatgcg tcacctaagg cctcgttcga taccgggctc
    19921 gacgtcttcg gcctcagccg cctgtcgacg gccgcggttg cccggtatgg cacccagttg
    19981 ctcacttcgt cccccgagcg cggcccccgt ggccggcacg ccgtctccct gcacgatatg
    20041 accgagttca ccttgcattc gaaggtgccg ctgccccttc agatggacgg tgaccacctg
    20101 gggctgcgga ccagcgtggc gttcacaggc gttcgccgtg cactgcgtgt gattgtgtga
    20161 gcagaagggg cgaaagtcct ttcactcgaa cgtttagacc agggtccacc ccatggaagt
    20221 acggctgtga cctagtcgac accgaagaat caaaaaaaac tttccggaag gggttgtatc
    20281 cgccgccgag gtttgcgagt ctcttcttgg cgatcggaac ggcccgcaac accggcctcc
    20341 acagatcacc agaacccctc ttcaaatcac aggaccacgc cagggcaacc tgacggtagg
    20401 cccttccctt gttgagggat tcgtgaaagc gttcacattc acaagcatcc cagcatgtaa
    20461 taccaaggag aggtagcagc catggactgg cgtcaccgcg ccgtttgccg cgaggaagac
    20521 cccgagctct tcttccccat cggcaacacc ggtcccgcgc tgctgcagat cgaggaagcc
    20581 aaggccgtct gccgtcgctg ccctgtcatg gagcagtgcc tgcagtgggc gctcgagtcc
    20641 ggccaggact ccggcgtctg gggtggtctc agcgaggacg agcgccgcgc aatgaagcgc
    20701 cgtgccgccc gcaaccgggc tcgtcaggcc tccgcctgac catccacccc tgctgacagc
    20761 ctgagcttgg cggcgtgtac agcgagtaca caacccccgc tcccgagccg cagcgcgcag
    20821 tacccccgat gcgcatcgga cgatggatcg cacgagcaca agccccggac cctcaccggt
    20881 ccggggcttt ttgctgcccg gccccgctcc ctacttgtcc gtgggcaccg ggatgtccag
    20941 gatcacccgg gtgccgcgct ccggagccgg gaccatgccg aaggcgccgc ccagctctcc
    21001 ctccaccagt gtgcggacga tctgcaggcc gaggttgccg gagcggtgcg ggtcgaagtc
    21061 ctcgggcagg ccgacgccgt cgtcctggac ggtgaccagg agccgggcct ccttcgtcgt
    21121 accgccacgg accgcggaga cctcgacggt gccggtgtcg ccgtcgc
//
