LOCUS       NZ_CP019724            26377 bp    DNA     linear   CON 01-JUN-2024
DEFINITION  Streptomyces pactum strain ACT12 chromosome, complete genome.
ACCESSION   NZ_CP019724
VERSION     NZ_CP019724.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces pactum
  ORGANISM  Streptomyces pactum
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Streptomyces pactum ACT12 Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2017) College of Life Sciences, Northwest A&F
            Unversity, No.22 Xinong Road, YangLing, Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2016
            Assembly Method                   :: SMRT v. 2.3.0
            Assembly Name :: version 2.3.0 of the PacBio Single Molecule Real
            Time
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002005225.1-RS_2024_06_01
            Annotation Date                   :: 06/01/2024 05:58:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,315
            CDSs (total)                      :: 7,221
            Genes (coding)                    :: 6,992
            CDSs (with protein)               :: 6,992
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 229
            CDSs (without protein)            :: 229
            Pseudo Genes (ambiguous residues) :: 0 of 229
            Pseudo Genes (frameshifted)       :: 84 of 229
            Pseudo Genes (incomplete)         :: 195 of 229
            Pseudo Genes (internal stop)      :: 15 of 229
            Pseudo Genes (multiple problems)  :: 62 of 229
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:20:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1913691
            Orig. end                         :: 1940068
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019724.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Northwest A&F Unversity.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26377
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="13"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26377
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26377
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16377](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16377)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(80..94)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    100..113
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(289..302)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.13"
                     /tool="antismash"
     misc_feature    complement(756..770)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            867..4145
                     /locus_tag="B1H29_RS07945"
                     /old_locus_tag="B1H29_07945"
     CDS             867..4145
                     /EC_number="3.1.21.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445135.1"
                     /locus_tag="B1H29_RS07945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07945"
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="WP_055419563.1"
                     /transl_table=11
                     /translation="MTHEDDGRDNHRPHESDWELLALDELGELAWEPAPGNAFAPGSDH
                     RRSWDDLILYPDLREAVERLNPGLPPDAVREAVATAAAPASQDTYEENRTAHEYLTTGI
                     RSVTYTDAFGAEHNPTISLVNLDDPDANVYRALNQVTVIDGEKNRRFDVVLYVNGLPVA
                     VLELKRAGDEDATLQTAHSQVTRYVQEFPTAFRYNAVVLLSDGITAKYGTPFTPYEHFA
                     PWNTDEFGNRVDVLEAEGIWDSGQNLALHGLFTQPRFLSLVRSFVNFVPSRRMKRIAKP
                     HQFYAVTRAAEAVREAAASDGKAGVVWHTQGSGKSEEMVLTTTMVMRDPALLNPTVVVI
                     TDRTDLDDQLFSTFLESEVLPESPHQVQTRAELREKLAAKGVGGILFTTLQKFGRTKEE
                     KESGADHPLLSDRRNIVVVVDEAHRSHYDSLNGYARHLRDALPHATLLAFTGTPISQDD
                     RNTRDVFGDKGAYDGYVDIYDLKRAADDGATVKVFHESRVISLVLDKDVDPTKIDEEAD
                     RITDGLDDTERRRVEQAVATMNAMYGTPARIRDLAENLVKHWEARRERMHPFVGVSEKG
                     GAAGKAMVVCATREICVRVYDALRELRPEWHSDEIDKGAMKVVFSTNSRKDPDRLLAHS
                     LSDTRRKAVINRAKDPDDELELLIVNNMLLTGFDAPPVHTMYLDRPLKGANLMQALARV
                     NRRFRAKQDGLLVGYAPLTENLQRAIAEYTEADQEDRTLGQDVDRALDELRNEYDVLSD
                     ILRGFGWRERLAMPARTAFIDAAIRAANYLRDPQTAGNDPEKLDDPRQTLGRRFRDHAH
                     RLERFYALCGSATNIGERFPDHPTWRRDIQFFVEVRAYMAKYDAMDREARGLPVARDVE
                     LYLAQLTSSVVETSGVTDLFAEAGLETADLTQLNDALVGRLLNSETPHLAAEALRRLIE
                     KKMREVTRHNVVRRTTFSERLQDLMVRYMRQQYTSAELIAKLIEMAKEVMEDSRRGEKF
                     DPPLDWRELAFYDAVADHGTARSVMGDEVLAGIARELVAEVRSKLKPDWIAREPVRARL
                     RSAIKRLLARRNYPPDQAPEAIDLVLKQMEHFANEWSTTNLPDD"
     gene            complement(4290..5378)
                     /locus_tag="B1H29_RS07950"
                     /old_locus_tag="B1H29_07950"
     CDS             complement(4290..5378)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008749703.1"
                     /locus_tag="B1H29_RS07950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07950"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_234393071.1"
                     /transl_table=11
                     /translation="MSIDTEHPSGEGGTTPVPAERSPLVVQWAERHGVEVARRLADAED
                     FADEVRRRLRPANTTDTYAKAWKVWTRFCGTQGFPELECTRGALVAFVVWLLDRGRVDG
                     KGYAPSSASTILAGAVVELRRRGAEVNRDDQAQARVTLEAAAVELLKAGERRGRGQAAA
                     AEVPDLYRVARACPDTLAGTRDKALVLTGFHYASRAQDPAGLLAGDVALTSRGLVVSVL
                     TGKTKHSVRDAKINYQQDPAICPVEAWKMYRARLAAEAPSHWSEPDAPAFVGVDRHGNV
                     TGGMVPDSVTRAVKRISARAGIPLAWTGHSLRIGLATTARKKGKDAVAIADQGGWARHS
                     RSMNGYFQRVDGWEDNATAGLT"
     misc_feature    5585..5600
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.85"
                     /tool="antismash"
     gene            5586..6191
                     /locus_tag="B1H29_RS07955"
                     /old_locus_tag="B1H29_07955"
     CDS             5586..6191
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477537.1"
                     /locus_tag="B1H29_RS07955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07955"
                     /product="hypothetical protein"
                     /protein_id="WP_234393072.1"
                     /transl_table=11
                     /translation="MKITIEGADKDFTEKLVALAAAHHAELTVAAVDTAWTVERATRFL
                     RSLTAGARRFAEMVIVDGDGYIDADQLRAAIGKLNGPTVALSRAVPRGVREGWWPEGIS
                     VPIAPVHDPDNPSWHKIIAYEMTSENVPVFRSAVAALATGRRAPVSPEPPAPWSGDAPS
                     AFAVPPGWGSGDDVPLVVLDEGGTHAGADTTSEHQQDR"
     gene            6297..6635
                     /locus_tag="B1H29_RS07960"
                     /old_locus_tag="B1H29_07960"
     CDS             6297..6635
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477538.1"
                     /locus_tag="B1H29_RS07960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07960"
                     /product="hypothetical protein"
                     /protein_id="WP_055419564.1"
                     /transl_table=11
                     /translation="MTALVSLALDQGLDLLGTALGQWLLVVLLAAAVAGTRLYRRSPAA
                     TPAEPPRVRRFTLLRTEEADGRPVRYETTRPTGTKITPWVSGRQRLFELTDVQLEDGTY
                     AAEPLDHF"
     gene            complement(6957..7499)
                     /locus_tag="B1H29_RS07965"
                     /old_locus_tag="B1H29_07965"
     CDS             complement(6957..7499)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030151 - molybdenum ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446277.1"
                     /locus_tag="B1H29_RS07965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07965"
                     /product="MOSC domain-containing protein"
                     /protein_id="WP_199832380.1"
                     /transl_table=11
                     /translation="MSGRVTAVSSNGEYSFTKPNRDSVRLLAGLGVEGDVHAGVTVKHR
                     SRMAQDPTQPNLRQVHLIHEELFDEVDDDGFKVAPGELGENITTRGIDLLGLPVGTLLR
                     IGDSAVLEVTGLRNPCLQIDNFQDGLLKQVVGRDEAGNIVRKAGIMSVVKEGGVVRPGD
                     SVETELPSGPHRPLDRV"
     gene            7799..8038
                     /locus_tag="B1H29_RS07970"
                     /old_locus_tag="B1H29_07970"
     CDS             7799..8038
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011039550.1"
                     /locus_tag="B1H29_RS07970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07970"
                     /product="hypothetical protein"
                     /protein_id="WP_055419566.1"
                     /transl_table=11
                     /translation="MAGIEIDDTTADALRALADAAGLPLDAYLAQVAEEKRRERALADG
                     AEIFRQVTSDPETAAAFDAEYGGPAPARTAARAA"
     gene            8042..8428
                     /locus_tag="B1H29_RS07975"
                     /old_locus_tag="B1H29_07975"
     CDS             8042..8428
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982770.1"
                     /locus_tag="B1H29_RS07975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07975"
                     /product="hypothetical protein"
                     /protein_id="WP_055419567.1"
                     /transl_table=11
                     /translation="MPAEYYVDYRWFLERQAELLDDLAVNDYSVFVGLAARHKVDPPRH
                     DQHHPDAFWRAAVMLEECVVLRPLPARNELYGFGVAVAYLGMHGERVNTKFEAWRDLIA
                     DITALRLDSFAVAERLRSLRLPAA"
     gene            complement(8760..9896)
                     /locus_tag="B1H29_RS07980"
                     /old_locus_tag="B1H29_07980"
     CDS             complement(8760..9896)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992140.1"
                     /locus_tag="B1H29_RS07980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07980"
                     /product="hypothetical protein"
                     /protein_id="WP_055419568.1"
                     /transl_table=11
                     /translation="MDPYGPAAQRFPLVARFRPPCLPLPERVRNLVELAGTAVEKSDQG
                     LASSACNQAALTASDAGLPDLARELCRRHAAAYLHACPLPGMSAIRGLEPVVNLARLHI
                     RAGRADEGRQRLLDLYAAVEAGTAAQFEGVAVPADLTATDEDRHEVRAWLWRVLLADGT
                     RTLTTTGRWAEAEAHIEAHRGVGSRMLDGRQTAVIAALTAGDTTRAAALLAETKPGDPW
                     EQAVTACLTVLCRRDAGQPVDRHVADLVTAYTGRKTDPGMTVFDIRFGLTILDATGSTE
                     PSVARRMVDDLHRRTINARDGYAARETLAHPLFTAIASSRQTQDCRDLVSACALGAGGM
                     PNESQAELTSIVRTSDSVIRASLARPFDSGRTPPMERG"
     gene            complement(10001..12079)
                     /gene="fxlM"
                     /locus_tag="B1H29_RS07985"
                     /old_locus_tag="B1H29_07985"
     CDS             complement(10001..12079)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543781.1"
                     /locus_tag="B1H29_RS07985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07985"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_055419569.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.2e-27, bitscore:
                     94.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 1.5e-45, bitscore: 154.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPDPWQQHNVTFADRESARRAIAERIAPALLAAEQDGQLTGWWF
                     MNKQPWPLRYRADEPSPAVETMLSDLVQDGTVVSWLPSIYEPETEAFGGTEAMEAAHEL
                     FHEDSRHLLTHRPGPEHLGRRETAVLLASAMMRAAGLDWFEQGDVWAKVAALRPVTGRP
                     PSARAAELVPAMRKLMTVDAQGLCRPGGPLAGHGGWVAAFERAGAELASLADRGALTRG
                     LRAVVAHHAIFHSNRAGLLRGDQSAMSDIAREVVMGTSDSPTPSGEAATGAQRVHVIND
                     TLAAPEADAERLRNTLVDQLRADGHARTPAVENALRTVPRHVFVPEAPLEDAYANAPVH
                     IKYDTDGTSISCASQPGVVALMLDQLDARPGERVLELGTGTGYNAALLAHLVGDSGHVT
                     TLDVDDDLVEGARAHLAAAGIGNVTAVTRDGALGHAEGAPYDRIIATVGAHGVPHAWLQ
                     QLAPGGRLLVPQRLKGTVSRSIAYEQRDGRWASLGSEMNTFMPLRRGIADDDRSVIPLS
                     TDGTVRLQAPAGQNIDADALAGVLYQPRTEEWTGVTVRAMESPEWMELFVTCSLPSGLI
                     RLLFPQTAKGTLLTEDPYPSSTAAVDKGAVAYLARRLSERKTPEGGRLWEFGVIGHGPC
                     SDELAAKAAEAIRTWDREYRGREATFEIQPLDAPAIEQRPGHFALDTPLNRIVVDWR"
     gene            complement(12104..13369)
                     /locus_tag="B1H29_RS07990"
                     /old_locus_tag="B1H29_07990"
     CDS             complement(12104..13369)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543780.1"
                     /locus_tag="B1H29_RS07990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07990"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_055419964.1"
                     /sec_met_domain="LANC_like (E-value: 8.4e-46, bitscore:
                     155.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAQAAQAPLDLVDAVAQQLTDPGSVLLPAAHRQHLAHGLPGIAL
                     LHIERAAAGLGPWQRAHDWLAAASRAPLTSGPDSHPFYGASAFAHALACAADHLPGAYR
                     RALDTLDRQTAADAIRRVDAAHHRIDTGRLPALAEFDTIRGLSGYGAHLLRRNPDSSAL
                     RAVLGYCVRLTRPITQDGDTLPGWWTETGPSGRPDERFPGGHANSGMAHGVGGVLALLA
                     LAARYGTFVAGHGEALDRILTWLDHWEDGSGPTWPYWITRAELRAGHPAPSAPRRPSWC
                     YGTAGLARARQLAALALGDTRRRLDAENALVAALTDPAQLKATRDNALCHGFAGLAHIA
                     ARAADDAHPSTSRRLRAVIPALLAAVHPPGTDPVHTATAIVQDEARGPGLLDGAAGIAL
                     ALLATNAAAPPRSAWDACLLVA"
     gene            complement(13366..16377)
                     /locus_tag="B1H29_RS07995"
                     /old_locus_tag="B1H29_07995"
     CDS             complement(13366..16377)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612044.1"
                     /locus_tag="B1H29_RS07995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_07995"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_055419965.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.4e-198,
                     bitscore: 658.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.7e-19,
                     bitscore: 69.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.9e-23, bitscore:
                     81.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAWLRTVLADYDLAEALEYASPVLAARVRSVCTSVEPSTARVAPS
                     TARVEPSARQVGRVALSVARYLLRSRHRATPFGLFAGVTVAGFGPQARASWGGEHVAVG
                     HAGAEWLAAVVERLESCPGLFERLPVVVNNTVTSRGDRFVVPFQSDDRSERTRAVEASL
                     ALTEPVRAVLAVAREPVRGGELVDKLQAEFPEAGPEKVRRLLAELVRRRVLITGLHAPS
                     TETDALGHLLDRLRTIDAADLPALAETARELGETRAMLTECASRGGRDSAAARMRALVP
                     GLRRHPVALDLRLDAQLVLPDAVARETERAALILTRLSGRPYGTAAWGAYHQRFYERYG
                     IGTMVPLQEVVADSGIGYPEGYPGTSPGARRPRLSARDDALVRLAQAAALDGSDEVVLT
                     DESIDGLDAGPDEPRLPPHLEMGVRVHAGSVDALQRGRFRLEIVSVSRGVGVTTGRFLG
                     VLAPADRAALAAELSGLPTADGDTVPAQLSFPPLLPESAHVARAPRVLPTVISLQEHRA
                     LADDVLGPADLAVGCDGRRMYLALPERGRRVEAVGMHALNLHTHTPPLVRFLAELPRAQ
                     SAQVTVFDWGAAAAMPFLPRLRYGRIVLVPARWRLEASELPGRAHPRTEWDAALTDWRA
                     RRRLPRRVHLVEDDRRLFLDLDEAGHRTLLRHHLDRVRQALLEEAAEPGAFGWCDGRAH
                     EVVVPLKATRPSSWPELPAPTPARALSHAQTQTPATSPVLLAALYGDPRRQDALLSRHL
                     PDLLERLGGPPWWFIRFRDPEQHVRLRIALPTPEAFAGTARTVSTWADELRGAGLLADL
                     RYPTSYRETGRWGSGDAWDAAEDVFRADSRAVLAQLSQRRRPHRRTLVAANAVSITSAF
                     LGGTEAGTRWLIDHVPPVAPGPVPRPQFTEAVRLADPGDDWSALRAVPGGAAVVSAWAD
                     RDAALAAYRRHLPGPHTQGIALDDVLTSLLHVHFVRHIAVNFPEEEICLHLARAAALAW
                     SARTTGRTPTGRTP"
     aSDomain        complement(15715..15990)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B1H29_RS07995_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="6.60E-22"
                     /identifier="RREFam001.1"
                     /label="B1H29_RS07995"
                     /locus_tag="B1H29_RS07995"
                     /protein_end="221"
                     /protein_start="129"
                     /score="69.0"
                     /tool="antismash"
                     /translation="VVVNNTVTSRGDRFVVPFQSDDRSERTRAVEASLALTEPVRAVLA
                     VAREPVRGGELVDKLQAEFPEAGPEKVRRLLAELVRRRVLITGLHAP"
     gene            complement(16599..16778)
                     /locus_tag="B1H29_RS08000"
                     /old_locus_tag="B1H29_08000"
     CDS             complement(16599..16778)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825826.1"
                     /locus_tag="B1H29_RS08000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_08000"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_055419570.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 3.7e-13, bitscore:
                     47.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSTVVPSNTQVNGRTPRPSDGFDLDVSLVEVADPAGLVNLTDD
                     NCGSTCGACTTNVA"
     gene            complement(16952..17398)
                     /locus_tag="B1H29_RS08005"
                     /old_locus_tag="B1H29_08005"
     CDS             complement(16952..17398)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825824.1"
                     /locus_tag="B1H29_RS08005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_08005"
                     /product="ATP-binding protein"
                     /protein_id="WP_055419571.1"
                     /transl_table=11
                     /translation="MTSLITLMQSAATGHPAYSQTFPCEPSTAEAGRTLVRDALGAWHL
                     DDLAEVTALIMSELIANAVTHTPCRSIRLIVGRPSAARVRAGVVDRAPYRLPVLGRAGE
                     DDESGRGLLLIDGIADRWGYDLHGPHRSPWGKEVWAELLMKTDG"
     gene            17639..18925
                     /locus_tag="B1H29_RS08010"
                     /old_locus_tag="B1H29_08010"
     CDS             17639..18925
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000004.1"
                     /locus_tag="B1H29_RS08010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_08010"
                     /product="hypothetical protein"
                     /protein_id="WP_055419572.1"
                     /transl_table=11
                     /translation="MDTTRNAVLEAWMAEHGYSSNSLADAVNGALERLTGRPGGLDGSS
                     VRAWKAGRVMWPKSATRKAIEDVSGLPAVALGFVPRGRPSSTPSPPQQEDPDMKRRTLV
                     GGIAAAAAAAAAAPGAAGPRRIGMSDVDRLNKRFAEIIASDHRHGGQLGIEQRAAALAD
                     EALNLQNAGSATQRVRSNLYASAAAFRSSAMWAAIDGRRYDVAKAHMREAQALAEMSGD
                     QAIKFRIWSHTGTMYRHMGRPADAFAANDVARNLYITRRDPMFASLGMARHAAIHGAAH
                     DRTGTRRAFDQAQEAMLRADPGDYRPVWLLAFYDQAELHSLALSAHLALGDYSTAEYHA
                     HRCLSALRPHMVRSRSITTTRLAHAQLAQGAADAATSTAMKVPADAATRHARVTRMLQE
                     FGAALRATAPRSSTVQTWTEHTASWRMAA"
     gene            18922..19461
                     /locus_tag="B1H29_RS08015"
                     /old_locus_tag="B1H29_08015"
     CDS             18922..19461
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337821.1"
                     /locus_tag="B1H29_RS08015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_08015"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_199832381.1"
                     /transl_table=11
                     /translation="MTTAPAIELRTFTTLDTARGDLLDVYADVRAPLLHLPNYAVTAFG
                     ERLDRHGGEPGFTAVLAYADEHPVGYAYANTIEHGDRYWQRTSPAPAAPYAERPAVALK
                     EIGVRPAWRKTGTARRIHDALLATRDEPFVTLMVNPAAGDGKVHALYRSWGYEDIGQSQ
                     PSPASPVLTVMVRAVR"
     repeat_region   19531..20534
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1933404..1933432
                     /rpt_unit_seq="gggaccatccccgcgggtgcggggagcag"
     gene            20891..21277
                     /locus_tag="B1H29_RS08020"
                     /old_locus_tag="B1H29_08020"
     CDS             20891..21277
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B1H29_RS08020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B1H29_08020"
                     /product="hypothetical protein"
                     /protein_id="WP_159027799.1"
                     /transl_table=11
                     /translation="MDASLDSTDRAQVMAAAWEAFAVAEQVADAVAFEEVGDELQALMA
                     AQASAAGRSLLPLPGLGRPVDVPPLSPGAEGLAPYVELLRHVQAALEHTAAEPGTEEGG
                     RAAVREAADKAATAAGALLATRER"
     gene            21280..23103
                     /locus_tag="B1H29_RS08025"
                     /old_locus_tag="B1H29_08025"
     CDS             21280..23103
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B1H29_RS08025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B1H29_08025"
                     /product="hypothetical protein"
                     /protein_id="WP_055419574.1"
                     /transl_table=11
                     /translation="MPTTLRELSETASRNLREVISDTLMPDDAREQSVVVRQLTNLVRH
                     LQTALESAGERPRRANPGPATHLATAQSALRRAAGRLPALDDEVAALHHGTPLARAVQA
                     AAAVQDLIASHRGRDGIPVTPYALAFTERPARSYLVHCSADLAWGAARVAHALGEAVTN
                     EGTAVQLYVARGSLDQASVFGRTAGGQMNRATEAFPHVPPLDPRPALPTDAPESITAHL
                     ADDCERLSRVAFEALHGRGESGLSGSDVQQLTRWRAMSDLLSGRILLHVATSVDPHTAE
                     PLREAAGRLRETAQAWQESAAQWHRVVDLSDPRVHPKLPLPSYHLARSGQFTHLPKTPP
                     HPALLTAHSHTTRLGQLLYGMAWNPETPGRPVQRDTREVLADAGGLAELTHTMYRVAAC
                     RGHALRRQADRIHSGDRQRGSPSSGGRASLLPAAQPPDETPRRALRARREGRAGSRRQH
                     PAHGCPYGHGHRARPAGRGRPQTDPVRSAVAARRRGGGTAVGAHAPRGLDCPPQCCGGA
                     QPVDNRHPFPEHEAHDVRSCHRPPVRRRHRAPPRSQQIAPGKVRCFTAPKTFLTVRHPA
                     GQPPSSPANPQEESDHSDVEEVAAPGDRPAG"
     gene            23352..24512
                     /locus_tag="B1H29_RS08030"
                     /old_locus_tag="B1H29_08030"
     CDS             23352..24512
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012318.4"
                     /locus_tag="B1H29_RS08030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_08030"
                     /product="S1 family peptidase"
                     /protein_id="WP_159027800.1"
                     /transl_table=11
                     /translation="MQSALVFHWLQSALEAAVNHHWQKFLQVPVVALLATVAATTPASA
                     EDGPAPLTSPTRAAALVAELGGHRTGGVYYEDGRLVVAVTDQAAARTVRNAGGAAKVVT
                     RSADELASIHDKLDQLGNIPNTAWGVEAATNQVNVEIFDGAPSDARSRIEKIAAAHPGA
                     VEISRINSRLVFKERLLGAVGITSDGWLCSAGFNAKNSSGAIYVLTAGHCVPGTGNIWY
                     MNWNNERIGVQNAYANGYGTSGWCDGVDRGCDWATIRADGSTIKPVEGVRYFNGTVKDI
                     TTSRFAAEREDSDRIGTMSEDTTGFITKTSVTVNISGKTMHGMYESNHCALGGDSGGPL
                     FHGSTALGLLSGGTAETTCNSSSSGEYRNYYTRVQTVVNERGLRIY"
     misc_feature    23427..23429
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            24615..25511
                     /locus_tag="B1H29_RS08035"
                     /old_locus_tag="B1H29_08035"
     CDS             24615..25511
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019357506.1"
                     /locus_tag="B1H29_RS08035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_08035"
                     /product="hypothetical protein"
                     /protein_id="WP_079160088.1"
                     /transl_table=11
                     /translation="MRIKAMHSVGLLTTVTVVGLTVSACGSQSDEKAEADAKAVSHRAE
                     QVAAAWDGSTAADKWRAGYYPMGDVVQLPHGGLRSKVDEQAYKDRSFVLRGKLPTDWPK
                     SGRVNWAGDESLTRPLSGAEESYRSLSGGLADGETGLTVTGAKLGTMTLATSRGPATVP
                     AWLFTLDGYTSPLKRAAADPSQLPPSPIGRARDIPVRQLNGLVDIAEDGRSVTVIALRG
                     VCHDGATVEALETVRSVVLSSSVKQQKDNEKCTKQARLRQVSVELEHPLGDRILLDAKS
                     GQPVPYKPPYGPSPSWS"
     gene            25700..25897
                     /locus_tag="B1H29_RS08040"
                     /old_locus_tag="B1H29_08040"
     CDS             25700..25897
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356323.1"
                     /locus_tag="B1H29_RS08040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_08040"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_055419576.1"
                     /transl_table=11
                     /translation="MPLPPTGWYKSSYSTDFEEACVEACVAAVGAGVLVRDAKDRDRRP
                     FPVSAPAWSSFLSALRPDGV"
ORIGIN
        1 aacaacgtac ggttcacata ccatcttttc caagtactgg atctcgctgg attcaattcg
       61 ggaagtgttc agcccatgct gaacaggaac tacatcagct ccttcccgat caaggtgccg
      121 gagcggccgg aacaggatgc catcgcgacc ctattgggcg cattggatga caagatcgat
      181 gtcaataggc gcatcgcggc cacgtacgaa cagctactcc actgcaagta caccgccatg
      241 ggcctgtccg gcgaacctga cgatgaacac gccattccag tcacggcctt gatcaccttc
      301 aatccaaagc taaccaaacc ctctgcagat gagccggtct atgtggacat ggccgcattg
      361 cagaccgatc aagccagcat cccaacatgg actcggcggg cacccaagtc cggcccacgg
      421 ttcatgaacg gtgacacact cctggcgcgc atcactccgt gcctagaaaa cgggaagacc
      481 ggatatgtcg acttcatgga ggatggcgag gtagggcttg gatccactga attcatcgtc
      541 atgcgctccc gcagtggggt ccctaaagaa ctcagctatt tcttggcgcg tgatgcaaga
      601 ttccgcgcac atgccattcg taacatgatc ggcacttccg ggcgccagcg cgtaagtgcg
      661 acggatgcag ctaactactt cgtaaaacga ccggaagcag aagctctggc ggtttttggt
      721 gaggaagccg caacagcgtt cgcccatgtt aaatccttgc agagtgagaa ccggctcctc
      781 ggcaccctcc gcgacaccct cctcccccag ctcatgtccg gccggctgcg cgtcaaggac
      841 gccgagaaga ttgtcgagga ccacgcatga cgcacgagga cgacggcaga gacaaccacc
      901 gcccccacga gtccgactgg gaactgctcg ccctcgacga gctgggcgag ctcgcctggg
      961 aacccgcgcc cggcaacgcg ttcgctcccg gctccgatca ccgcaggtcg tgggacgacc
     1021 tgatcctcta ccccgacctc cgtgaggccg tcgagcggct caaccccggc ctgcccccgg
     1081 acgccgtccg cgaggccgtc gccacggccg cggccccggc gtctcaggac acgtacgagg
     1141 agaaccgcac cgcccacgag tacctgacga ccggcatccg ctccgtcacg tacaccgacg
     1201 ccttcggcgc cgagcacaac ccgaccatca gtctcgtcaa cctggacgat cccgacgcga
     1261 acgtctaccg cgcgctcaac caggtcaccg tcatcgacgg tgagaagaat cgccgcttcg
     1321 acgtcgtcct gtacgtcaac ggcctgcccg tcgccgtgct ggagctgaag cgggccggcg
     1381 acgaggacgc cacgctccag acggcgcact cgcaggtcac ccggtacgtc caggagttcc
     1441 cgaccgcctt ccgctacaac gcggtggtcc tgctctccga cggcatcacc gcgaagtacg
     1501 gcacgccctt caccccgtac gagcacttcg cgccgtggaa cacggacgag ttcggcaacc
     1561 gcgtcgacgt gctagaggcc gagggcatat gggactcggg acagaacctc gccctgcacg
     1621 gcctgttcac ccagccgcgc ttcctctccc tcgtccggtc cttcgtcaac ttcgtcccgt
     1681 cgaggcggat gaagcggatc gccaagccgc accagttcta cgcggtgacc cgcgccgccg
     1741 aggccgtacg agaggccgcg gcaagcgacg gcaaggccgg cgtcgtctgg cacacgcagg
     1801 gctcgggcaa atccgaggag atggtgctca ccacgacgat ggtgatgcgc gacccggcgc
     1861 tgctgaaccc gacggtcgtg gtcatcacgg accgaaccga cctcgacgac cagctgttct
     1921 ccaccttcct cgagagcgag gtcctcccgg agagcccgca ccaggtgcag acccgggccg
     1981 agcttcgcga gaaactggcg gccaagggcg tcggcggcat cctcttcacc acgctgcaga
     2041 agttcggccg tacgaaagag gagaaggagt ccggcgcgga ccatccactc ctctccgacc
     2101 ggcgcaacat cgtggtggtc gtcgacgagg cgcaccgcag ccactacgac tccctcaacg
     2161 gctacgcccg ccacctgcgt gacgcgcttc cgcacgccac gctgctggcc ttcaccggca
     2221 ccccgatctc ccaggacgac cgcaacaccc gtgacgtgtt cggcgacaag ggcgcgtacg
     2281 acggctacgt cgacatctac gacctcaagc gggccgccga cgacggggcc accgtcaagg
     2341 tcttccacga gagccgggtg atctcgctcg tcctcgacaa ggacgtcgat cccacgaaga
     2401 tcgacgagga ggccgaccgc atcaccgacg gtctcgacga caccgagcgc cgccgcgtcg
     2461 agcaggccgt cgccacgatg aacgcgatgt acggcacgcc cgcccgcata cgggacctcg
     2521 ccgaaaacct ggtaaagcac tgggaggcgc ggcgagagcg gatgcatccg ttcgtcggcg
     2581 tctcggagaa gggcggtgcg gccggcaagg cgatggtcgt gtgcgcgacc cgggagatct
     2641 gcgtccgcgt ctatgacgcc ctgcgcgagc tgcggcccga atggcacagc gacgagatcg
     2701 acaagggcgc catgaaggtc gtcttctcca cgaactcgcg caaggacccc gaccgcctgc
     2761 tcgcccactc cctgagcgac acccggcgga aggcggtcat caaccgggcg aaggaccccg
     2821 acgacgagct cgagctgctc atcgtcaaca acatgctgct gaccggcttc gacgccccgc
     2881 cggtccacac gatgtacctg gaccggccgc tcaagggcgc caacctgatg caggcgctgg
     2941 cccgcgtcaa ccgccgcttc cgtgcaaagc aggacggcct cctcgtcggg tatgcgccgc
     3001 tgaccgagaa cctccagcgg gcgatcgccg agtacaccga ggccgaccag gaggaccgca
     3061 cgctcggaca ggacgtcgac cgggctctgg acgagctgcg caacgagtac gacgtcctct
     3121 cggacatcct gcgcggtttc ggctggcggg aacggctggc catgccggcg aggacagcgt
     3181 tcatcgacgc cgccatccgg gccgccaact acctccggga cccgcagacc gcgggcaacg
     3241 acccggagaa gctggacgat ccccggcaga ccctcgggcg ccgcttccgc gaccacgccc
     3301 accggctgga gcgcttctac gcgctgtgcg gcagcgccac gaacatcggc gagcggttcc
     3361 cggaccaccc gacctggcgg cgggacatcc agttcttcgt cgaggtccgc gcctacatgg
     3421 cgaagtacga cgcgatggac cgcgaggcgc gcggtctgcc ggtggcccgc gatgtcgagc
     3481 tgtacctggc gcagctgacc tcctcggtcg tcgagaccag cggcgtgacg gacctgttcg
     3541 cggaggccgg cctggagacc gccgacctga cgcagctcaa cgacgcgctc gtcggccggc
     3601 tgctgaacag cgagaccccg cacctggcgg cggaggcgct gcggcggctc atcgagaaga
     3661 agatgcgtga ggtgacacgg cacaacgtcg tgcgccgcac gacgttctcc gagcggcttc
     3721 aggacctgat ggtccggtac atgcggcagc agtacacgag cgctgagctc atcgccaagc
     3781 tgatcgagat ggccaaggag gtcatggagg acagccggcg cggcgagaag ttcgacccgc
     3841 cgctggactg gcgcgagctc gccttctacg acgcggtcgc cgaccacggc acggcgcgtt
     3901 cggtgatggg cgatgaggtg ctggccggga tcgcccgcga actggtcgct gaggtacgga
     3961 gcaagctcaa gccggactgg atcgcccgcg agccggtccg ggcccgcttg cgcagcgcca
     4021 tcaaacgcct cctggcccgc cgcaactacc ctccggacca ggccccggag gccatcgacc
     4081 tggtgctgaa gcagatggaa cacttcgcca acgagtggtc caccaccaac ctcccggacg
     4141 actgacacac gcgatctgcg cactcgtcgt ccgcgcttcg ccccggcacc ggtcctccgt
     4201 gccggaacga agcagccttc ctgcgtggcg agtccagggc catgtggttc tggtcttgtc
     4261 gcgggcggcc tcctgtcgcc gcccactggt caggtgaggc cggcggtggc gttgtcctcc
     4321 cagccgtcga cccgctggaa atagccgttc atggagcggg agtgccgggc ccagccgccc
     4381 tggtcggcga tcgccacggc atccttgccc ttcttgcggg cggtcgtggc caggccgatg
     4441 cggagggagt ggccggtcca ggcgagcggg atcccggcgc gggcgctgat ccgcttcacg
     4501 gcccgggtga cggagtcggg gaccatgccg ccggtgacgt tgccgtgccg gtcgacgccg
     4561 acgaacgcgg gggcgtccgg ctccgaccag tgcgacgggg cctcggcggc gaggcgggcc
     4621 cggtacatct tccacgcttc caccgggcaa atcgccggat cctgctggta gttgatcttc
     4681 gcatcacgga cgctgtgctt cgtcttgccg gtgagcaccg acacgaccag gccgcgcgag
     4741 gtgagggcga cgtctccggc gaggagtccg gcggggtcct gggcacgcga ggcgtagtgg
     4801 aagccggtca ggacgagcgc cttgtcccga gttccggcga gggtgtcggg gcatgccctc
     4861 gccacccggt acaggtcggg gacctcggcc gcggcggcct ggccccggcc tcgccgctcc
     4921 cccgccttca gcaactccac ggctgccgcc tccagggtca cccgggcctg cgcctggtcg
     4981 tcccggttca cctccgcgcc acggcggcgc agctccacga cggctccggc gaggatcgtg
     5041 ctcgccgacg acggggcgta gcccttcccg tccacccggc cccggtccag cagccacacg
     5101 acgaacgcca ccaacgcacc acgcgtgcat tccagttcgg gaaagccctg cgttccgcag
     5161 aaccgcgtcc agaccttcca cgccttcgcg tacgtgtccg tcgtgttggc cggtcgcagt
     5221 cgccgccgta cctcgtccgc gaagtcctcc gcgtccgcca ggcgccgcgc gacctcgaca
     5281 ccgtggcgct ccgcccactg gacgaccagc ggggaccgct ccgccggaac gggagtcgtg
     5341 cccccctctc ccgacgggtg ctcggtgtcg atgctcaaca ggcactcccc cgattgttca
     5401 tgacgtcgga taaggagagg ttatccgatg ccagatgtcc cgtcgtgccc agccgccgga
     5461 cagatcacct ctcctcatgg agaattccgg ccagattctt cgggtgctac atgcctgccg
     5521 ggaagcgcgg gcctactctt catggagatc ccgcagaact gagtaagaat ctgacggaag
     5581 gccatatgaa gatcacgatc gagggcgcgg acaaggactt caccgagaag ctcgtcgcgc
     5641 tcgccgcagc gcaccacgca gaactgactg tcgcggccgt cgacaccgcc tggaccgtcg
     5701 agcgcgccac gcgcttcctg cgctcgctga ccgccggcgc ccgccggttc gccgagatgg
     5761 tcatcgtcga cggcgacggt tacatcgacg cggaccaact acgcgccgct atcgggaaac
     5821 tcaacggccc gaccgtcgcc ctgtcccgtg ccgtcccgcg cggcgtgcgc gagggctggt
     5881 ggcccgaagg catcagtgtg cccatcgccc cggtccacga cccggacaat cccagctggc
     5941 acaaaatcat cgcctacgag atgaccagcg agaacgtgcc cgtcttccgt tccgccgtcg
     6001 ccgccctggc caccggccgt cgggcccctg tgtcacctga accacctgcc ccctggagcg
     6061 gggatgcgcc gtcggccttc gccgtgccac ccggctgggg ctccggcgac gacgtaccgc
     6121 tggtcgttct cgacgagggc ggcacccatg caggggccga caccaccagc gagcatcagc
     6181 aggacagatg aggcagatca aatgggggtt gcgcgcctaa cacccctctc ccgcacagtc
     6241 ggcgcggtcc gtcaccccgg cgggccatga ccgcgccacc caggagtgat gccgccatga
     6301 ccgccctcgt ctccctcgcc ctcgaccagg gcctggatct tctcggaacg gccctgggcc
     6361 agtggctgct cgtcgtactt ctcgccgctg ccgtcgccgg tacccggctg taccgacgga
     6421 gcccggccgc cactcccgcc gagccgcctc gcgtacgccg cttcaccctc ctgcgcaccg
     6481 aggaagccga cggcaggccc gtgcggtacg agaccacccg gcccaccggg accaagatca
     6541 ctccttgggt cagcggccgc caacgcctct tcgaactgac tgacgtgcag ttggaggacg
     6601 ggacctacgc agccgagccc ctcgaccatt tctgaccagc gagtgcagtc gatgcagtca
     6661 gcttcagcca ccggcgcccg tggccgcccc gccggccata gggccgattc cacgccagat
     6721 cagggcccca aacccagcac tggcgccccg tccaggagcg gcacgctggt cgctgtctgt
     6781 ccgggggtgg tgtccgtccg tcccagtcca cgtacggtga gcacgatggc ggccgacagc
     6841 acggccacca cgtccgccac cagtacgaca agcagccttc cagcggcaag ggggtccttg
     6901 ccgctggaag gctgcctgtc ggcgggttcg ggcatggctc gacctcggcg agccggtcag
     6961 acccggtcga ggggtcggtg cggaccgctg ggaagttccg tctcgacact gtcgccgggg
     7021 cgcaccacac cgccttcctt cacgacgctc atgattccgg ccttgcgcac gatgttcccc
     7081 gcctcgtcgc gaccgacgac ctgcttcagc agtccgtcct ggaagttgtc gatctgcagg
     7141 cagggattgc ggaggccggt aacctccagg actgcggagt cgccgatgcg cagcagtgtg
     7201 ccgaccggca gaccgagcag atcgatgcca cgcgtggtga tgttctcgcc gagttcgccg
     7261 ggcgccactt tgaatccgtc gtcgtcgacc tcgtcgaaaa gctcctcatg aatgaggtgg
     7321 acctggcgca ggttcggctg ggtgggatcc tgcgccatgc gcgagcggtg cttgaccgtc
     7381 acaccggcat gcacgtcccc ctccacaccg agcccggcga gcaacctgac gctgtccctg
     7441 ttcggcttgg tgaacgagta ctccccgttg ctgctgaccg ccgtcactct cccgctcatg
     7501 cctcggaacc ccctcgtcgg tgaccgtgtc cggccatgag cctagccctg gccgcagcac
     7561 gggagcctcc gggcgttcgg cagatacttc gctctgctcg accagcccga ccgcaccttc
     7621 gacctcgggt gtcgccgcta ctggccggca tcaaggcgtc gggcagcgtc atcgctccgc
     7681 tcgggcgcca agaggtgcct ggctgatcga agtggcggaa gcgatcagaa accagcaggt
     7741 caaagcgtaa tttccaggtg gctggcctgg gcgtggtctc gcgcggcata ctcgtggcat
     7801 ggctggcatc gagatcgacg acaccaccgc agatgcactg cgggccctgg ccgacgcggc
     7861 agggctgccg ctggacgcct acctcgcgca ggtcgccgag gagaagcggc gcgagcgcgc
     7921 gctggccgac ggcgcggaga tcttccggca ggtcaccagc gacccggaaa cggccgctgc
     7981 gttcgacgct gaatacggag gccccgcgcc ggcccggacc gccgcgcggg cggcctgacc
     8041 tgtgcctgcc gagtactacg tcgactaccg gtggttcctg gaacgccagg ccgagctgct
     8101 ggacgatctc gcggtcaacg actactccgt gttcgtcggc ctggccgccc ggcacaaggt
     8161 cgacccgccg cgccacgacc agcaccaccc ggacgccttc tggcgtgcgg ccgtgatgct
     8221 tgaggagtgc gtcgtgctcc ggccgctgcc cgcccgcaac gagctgtacg gcttcggtgt
     8281 ggccgtggcg tacctcggga tgcacgggga gcgggtgaac accaagttcg aggcctggcg
     8341 ggacctgatc gccgacatca ccgccctgcg tctcgactcg ttcgcagtgg ccgaacggct
     8401 ccgctcgctg cgcctgccgg cggcctgacc ccgctgtccg ccacatccag ggctcccgta
     8461 gacggtcgga aggccggtgg aggtaacagg cgggacgtct tgttgaggac catccccgcg
     8521 ggtgcgggga gcagttcacc gcgccgatcg cggccaggta ggcgccggga ccatccccgc
     8581 gggtgcgggg agcagactgc ttgacctgcg tgtttatggc cgcagagacg cggtttcggt
     8641 gactttcacc ggttccggca aatagggcat cgggggctcc atgggtactt ggagggccag
     8701 ccgctcatcc tacttcttgg acgtttcctc ttcccgcgaa ctcttcgagc cgcgcttcct
     8761 cagcctctct ccataggagg cgtacgtccg gaatcgaacg gtcgggcgag acttgcccgg
     8821 atcacgctgt cgctggtgcg cacgatcgaa gtgagttctg cttgcgactc gttcggcatg
     8881 ccgcctgccc cgagggcgca ggcactcacc aggtcgcggc aatcctgcgt ttgtcggctt
     8941 gaggcgatcg cggtgaacaa agggtgcgcc agggtctcgc gagccgcgta gccgtcccgg
     9001 gcgttgatgg tcctgcggtg aaggtcgtcg accatgcggc gcgcgacaga tggctcggtg
     9061 gagccggtcg cgtcgaggat ggtgaggccg aaccggatgt cgaagacggt catgcccggg
     9121 tcggtcttcc gcccggtgta tgccgtcacc aggtcggcca cgtggcggtc gaccggctgc
     9181 ccggcgtcgc ggcggcacag gacggtcagg caggccgtca cggcctgttc ccacgggtcg
     9241 ccgggcttcg tctcggcgag aagggcagcg gcccgggtcg tgtcgccggc ggtgagcgcg
     9301 gcgatcaccg cggtctggcg cccgtcgagc atccggctgc cgacgccgcg gtgggcttcg
     9361 atgtgtgctt cggcctcggc ccatcgtcct gtggtggtga gagtgcgggt gccgtcggcg
     9421 aggaggacgc gccacagcca cgcgcggacc tcgtggcggt cctcgtcggt cgcggtgagg
     9481 tccgccggta cggcgacgcc ctcgaactgg gcagccgtac ccgcctcgac cgccgcgtac
     9541 aggtcgagca gccgctgtcg tccctcgtcc gcgcggccgg cgcggatgtg gaggcgggcg
     9601 aggttgacga ccggttccag gccccggatc gcgctcatgc cgggcagggg gcaggcgtga
     9661 aggtaggcgg cggcgtgccg gcggcacagt tcgcgggcga ggtcggggag gccggcgtcg
     9721 gaggcggtga gcgcggcctg gttgcaggcg gacgatgcga ggccctggtc gctcttctcg
     9781 accgcggtgc cggcgagttc gacgaggttg cgtacgcgct cggggagagg gagacacgga
     9841 ggccggaatc gggcgacgag cgggaagcgc tgggctgcgg gtccgtacgg gtccatgggt
     9901 cccccgggcg tgagtgggag ctggagcgct gctgggacgg tgggtgcccg tccgccgtac
     9961 gtcggcgggc gggcacccac cgtccgctac gcgtggtgcg tcagcgccag tcgacgacga
    10021 tgcggttcag cggggtgtcg agagcaaagt ggccggggcg ctgctcgatg gcgggggcgt
    10081 cgaggggctg gatctcgaag gtggcctcac ggccgcggta ctcccggtcc caggtgcgga
    10141 tggcctcggc ggccttcgcg gccagctcgt cgctgcaggg gccgtgaccg atcacgccga
    10201 actcccagag cctgccgccc tccggcgtct tccgttccga caagcgccgc gccaggtagg
    10261 cgacggcgcc cttgtcgacc gccgcggtcg acgaggggta ggggtcctcc gtgagcagag
    10321 tgcccttggc ggtctggggg aacagcagcc ggatcaggcc cgaggggagg gagcaggtca
    10381 cgaacagttc catccactcg ggcgactcca tggcgcggac cgtcacgccg gtccactcct
    10441 cggtgcgcgg ctggtacagg acgccggcga gggcgtcggc gtcgatgttc tgcccggccg
    10501 gggcctgcag gcgtacggtg ccgtccgtgc tcagcgggat gacgctgcgg tcgtcgtcgg
    10561 cgatgcccct gcgaagcggc atgaaggtgt tcatctcgct gccgagggac gcccatcggc
    10621 cgtcgcgctg ctcgtaggcg atggagcggg agacggtgcc cttgaggcgc tgggggacga
    10681 ggagccggcc gccgggtgcg agctgctgca gccaggcgtg cggcacgccg tgcgcgccga
    10741 cggtggcgat gatgcggtcg tacggtgcgc cttcggcgtg gccgagggcc ccgtcgcggg
    10801 tcaccgccgt gacgttgccg atccctgcgg cggcgagatg cgcgcgggcg ccctccacca
    10861 ggtcgtcgtc gacgtcgagg gtggtcacgt gtccgctgtc gccgaccagg tgggcgagga
    10921 gagcggcgtt gtagccggtg ccggtgccga gttcgaggac gcgctcgccg ggccgggcat
    10981 cgagctggtc cagcatgagg gcgacgacgc ccggctggga ggcgcaggag atcgaggtgc
    11041 cgtcggtgtc gtacttgatg tgcacgggcg cgttggcgta ggcgtcctcg agcggcgcct
    11101 cgggcacgaa cacgtggcgc gggacggtcc gcagtgcgtt ttcgacggcg ggcgtacggg
    11161 cgtgcccgtc cgcgcgcaac tggtcgacca gggtgttccg gaggcgctcg gcgtccgctt
    11221 cgggtgcggc gagcgtgtcg ttaatgacgt ggacgcgctg cgcgccggtc gctgcttcgc
    11281 cggacggtgt ggggctgtcg ctcgttccca tgactacctc tcgtgcgatg tcggacattg
    11341 cgctctggtc gcctctgagg aggccggcgc ggttggagtg gaagatcgcg tggtgggcga
    11401 cgacggctcg aagaccgcgt gtgagggcac cacgatcagc gagggaagcc agctcggcac
    11461 ctgccctctc gaacgcggcc acccatccgc cgtgcccggc gagcgggccg cccgggcggc
    11521 acaggccctg ggcgtccacg gtcatcagct tgcgcatcgc gggcaccagt tcggcggccc
    11581 gtgcggaggg cggacggccg gtgaccggcc ggagggcggc gaccttcgcc cacacgtcac
    11641 cctgctcgaa ccagtccagg cctgccgccc gcatcatcgc gctcgccagc agtacggcgg
    11701 tttcccggcg cccgaggtgc tccggcccgg gccggtgggt gagcaggtgg cggctgtcct
    11761 cgtggaacag ctcgtgagcg gcttccatgg cctcggtccc gccgaatgcc tcggtctcgg
    11821 gctcgtagat gctcggcaac catgacacga ccgtgccgtc ctggacgagg tcgctcagca
    11881 tcgtctcgac ggcgggtgat ggctcgtcgg cgcggtaccg aagcggccag ggctgcttgt
    11941 tcatgaacca ccagcccgtg agctgcccgt cctgttcggc ggcgaggagg gcgggggcga
    12001 tgcgttcggc gatggcgcgc cgggcgctct cgcggtcggc gaaggtgacg ttgtgctgct
    12061 gccaggggtc cgggggcatg cggatgtcct tcggtcgatg gggtcaggcg acgagcaggc
    12121 aggcgtccca ggcggaccgg ggcggtgcgg cggcgttggt cgcgaggagg gccagagcga
    12181 tgccggctgc gccgtcgagg aggccggggc cacgcgcttc gtcctggacg atcgccgtgg
    12241 cggtgtgcac ggggtcggtg cccggcggat ggacggcggc caggagtgcc gggatcacgg
    12301 cgcggagccg tcgggaggtc gaggggtggg cgtcgtcggc cgcgcgggcc gcgatgtggg
    12361 cgaggccggc gaatccgtgg cacagggcgt tgtccctcgt cgccttgagc tgggcggggt
    12421 cggtgagggc ggccacgagc gcgttctcgg cgtccagccg gcggcgggtg tcgccgaggg
    12481 cgagtgcggc gagttgccgg gcccgggcga gacctgcggt gccgtagcac catgacggcc
    12541 gccgtggcgc ggacggggcg gggtggccgg cgcgcagctc ggcccgggtg atccagtacg
    12601 gccaggtcgg cccgctaccg tcctcccagt ggtccagcca ggtcaggatg cggtccagtg
    12661 cttcgccgtg cccggcgacg aaggtgccgt accgggcagc gagcgccagc agggcgagta
    12721 caccgcctac gccgtgcgcc atgccgctgt tggcgtgtcc gcctgggaag cgttcgtccg
    12781 ggcggcccga ggggcccgtt tccgtccacc agcccggcag ggtgtctccg tcctgggtga
    12841 tcggccgggt gaggcgtacg caatagccga ggacggcgcg cagggcggac gagtcggggt
    12901 tgcggcgcag gaggtgggcg ccgtagccgg acaggccccg gatggtgtcg aactcggcga
    12961 gcgccgggag gcgcccggtg tcgatgcggt ggtgagcggc gtcgacgcgg cggatcgcat
    13021 cggccgccgt ctgccggtcc agggtgtcga gagcgcgtcg gtaggcaccg ggcaggtgat
    13081 cggcggcgca ggccagggcg tgcgcgaagg cggacgcccc gtagaacggg tggctgtcgg
    13141 ggccgctggt gagcggtgcg cgggatgctg cggcgagcca gtcgtgggcg cgctgccacg
    13201 ggccgaggcc ggccgcggcc cgctcgatgt gcagcagcgc gatgccgggg aggccgtggg
    13261 cgaggtgctg ccggtgtgcc gccggcagga gcacactgcc ggggtcggtg agctgctggg
    13321 cgacggcgtc gaccaggtcg agcggggcct gtgcggcctg tgcggtcatg gcgttctccc
    13381 agtaggtgtt ctcccagtgg tgcgtgcgga ccacgccagg gcggcagcgc gggcgaggtg
    13441 gaggcatatc tcctcttcgg ggaagttcac cgcgatgtgc cgtacgaaat ggacgtgcag
    13501 cagcgaagtc aggacgtcgt cgagggcgat gccctgcgtg tggggtccgg gcaggtgccg
    13561 ccggtaggcg gcgagcgccg cgtcccggtc cgcccacgcc gacacgacgg ccgctcctcc
    13621 gggtacggcg cgcagtgccg accagtcgtc gccggggtcg gccagacgta cggcttcggt
    13681 gaactgcggg cgcggcacgg gcccgggcgc cacgggcggc acgtggtcga tcagccagcg
    13741 cgtcccggct tccgtgccgc cgaggaacgc ggaggtgatg gagacggcgt tcgcggccac
    13801 cagcgtgcgc cggtgcggac gccgccgttg ggagagctgg gccaggacgg cgcgcgagtc
    13861 cgcgcggaac acgtcctcgg ccgcatccca tgcgtcgccg gagccccagc gccccgtctc
    13921 ccgataggag gtcgggtacc gcaggtccgc caacagccct gcaccgcgca gctcgtcggc
    13981 ccacgtactc actgtccggg ccgtcccggc gaacgcctcg ggagtgggga gcgcgatgcg
    14041 caggcgcacg tgctgctcgg ggtcgcggaa gcggatgaac caccacggcg gtccaccgag
    14101 tcgttcgagc agatcaggca ggtggcggga gagcagcgcg tcctggcggc gggggtctcc
    14161 gtacaacgcg gccagcagta ccggcgaagt ggccggggtc tgcgtctggg catgggagag
    14221 ggcgcgtgcg ggagtggggg cgggcagctc cggccacgac gacggccggg tcgccttgag
    14281 cggcaccacc acctcgtggg cccggccgtc gcaccagccg aacgcccccg gttccgccgc
    14341 ctcctcgagc agggcctggc gcactcggtc gagatggtgg cgcagcagcg tccggtggcc
    14401 ggcctcgtcg aggtcgagga agaggcgccg gtcgtcctcc acgaggtgga cccgccgagg
    14461 cagccgccgc cgtgcccgcc agtcggtgag ggcggcgtcc cattcggtcc ggggatgcgc
    14521 gcgaccaggc agctcggatg cctcgagtcg ccagcgggcc ggaacgagca cgatgcgccc
    14581 gtaccgcagg cgcggcagga acggcatcgc cgccgcggcg ccccagtcga acacggtgac
    14641 ctgcgcgctc tgggcgcggg gcaactcggc gaggaaccgc acgagcggcg gagtgtgcgt
    14701 atggaggttc aacgcgtgca tcccgacggc ctcgacgcgc cggccacgct ccgggagggc
    14761 cagatacatg cggcggccgt cgcaccccac cgccaagtcc gcgggtccga ggacgtcgtc
    14821 ggcgagggcg cggtgttcct ggaggctgat cacggtcggc aggacccgcg gggcccgcgc
    14881 gacgtgggca ctctccggca ggagcggcgg aaaggagagc tgggcgggca cggtgtcgcc
    14941 gtcggcggtc ggaaggccgg acagttcggc ggccaaggcc gcacggtcgg ccggggccag
    15001 aacgccgagg aagcggcccg tggtcacgcc gacgccgcgg gacacgctca cgatctccag
    15061 ccggaacctc ccgcgctgca acgcgtccac gctgccggca tggacccgta cccccatctc
    15121 caggtgcggt ggcagtcggg gttcgtcggg ccctgcgtcc aggccgtcga tcgactcgtc
    15181 ggtgaggacc acctcgtcac tgccgtcgag cgcggcggcc tgcgccagcc gtacgagggc
    15241 gtcgtcacgg gcggagaggc gcggccggcg ggcgccgggc gaggtacccg ggtagccctc
    15301 ggggtaaccg atgccgctgt cggcgacgac ttcctgaagc ggcaccatgg tgccgatgcc
    15361 gtaccgctcg tagaaccgct ggtggtacgc accccacgcc gcggtgccgt acgggcgacc
    15421 gctgagcctg gtcaggatca gtgcggcgcg ctcggtctcg cgggcgaccg cgtccggcag
    15481 tacgagctgc gcgtccaggc gcaggtcgag tgcgacgggg tggcggcgca gccccggcac
    15541 gagagccctc atccgcgctg ccgcgctgtc gcgcccaccg cgcgaggcgc actccgtcag
    15601 catggcccgg gtctccccca gttcgcgcgc ggtctcggcc agagccggga ggtcagcggc
    15661 gtcgatggtg cggagccggt cgagcaggtg tccgagggcg tcggtctcgg tgctcggcgc
    15721 gtgcaggccc gtgatcagca cccgtcgtcg gaccagctcc gccagcagtc ggcgtacctt
    15781 ctccggcccg gcctcgggaa actccgcctg gagcttgtcc acgagttcac cgccccggac
    15841 cggctcccgc gccacggcga ggaccgcgcg cacgggctcg gtcagggcga gggacgcctc
    15901 caccgcgcga gtccgctcgc tccggtcgtc ggattggaac ggcacgacga accggtcgcc
    15961 gcggctcgtc acggtgttgt tgacgacaac gggcagtcgt tcgaagaggc ccgggcagga
    16021 ctccagccgc tcgacgacag cggccagcca ctccgcgccc gcatggccga cggccacgtg
    16081 ctcgccaccc cagctcgcgc gcgcctgcgg gccgaatccc gcgacggtca caccggcgaa
    16141 gagcccgaac ggcgtagccc tgtgccggga acgcagcagg tagcgcgcca cggacagcgc
    16201 cacacgcccc acctgccgcg cggacggctc aacgcgcgcc gtggacggtg caacgcgcgc
    16261 cgtggacggt tcaacggacg tgcacacgct ccgtaccctc gcggccagaa ccgggctggc
    16321 gtactccagg gcttcggcga ggtcgtagtc ggcgaggacg gtacgcagcc acgcgatgca
    16381 ggcggcgact ccgtcggcgg agcggtcgtc ggggtcggga agcggaggac acggcggttc
    16441 cgggcgggca acggctcgta cgaaagcggt cgtgccggca cggaacgccg gatacggatc
    16501 agccaccact acctccgtgg gtgagggacg gcgactggtg ccgccacgcc acacggcgcg
    16561 gcagcaccag cccgcgaaga cgcgaagccc tggggtggtc aggcgacgtt cgtggtgcag
    16621 gcgccgcagg tggatccgca gttgtcgtcg gtcaggttga ccaggcccgc cgggtcggcc
    16681 acctcgacga gggagacgtc caggtcgaag ccgtccgacg gcctcggcgt ccgcccgttc
    16741 acctgcgtgt tgctcgggac tacggtgctg cgtgtcatgc caactcctct acgtcggaat
    16801 gcttctgtgc ggtgcagccc gcctccggcc gtacggcacg gcgccgcctg atcggggcgg
    16861 gagtctggtg agacggcagc cggccgtcgc tttcgagagg tcatgcggag gcggatgacg
    16921 tccggaaagc ccgaggccgc cacggaggtg ctcacccgtc tgtcttcatc aggagttcgg
    16981 cccagacctc cttgccccac gggctcctgt gcgggccgtg caggtcatag ccccagcggt
    17041 cggcgatgcc atcgatcagg agcaggccac gccctgactc gtcgtcctcg ccggcccggc
    17101 cgaggaccgg caggcggtat ggcgcccggt ccaccacccc ggcccgtacc cgtgccgcgc
    17161 tcggccgccc gacgatcaga cggatcgatc ggcacggcgt gtgcgtgacg gcgttcgcaa
    17221 tcagctccga catgatcagc gcggtgacct cggcgaggtc gtcgaggtgc catgcaccga
    17281 gggcgtcacg aacgagcgtc cggccggctt cggcagtgga cggctcgcac gggaaggtct
    17341 ggctgtaggc gggatgcccg gtggcagcgg attgcatgag cgtgatcaga ctcgtcatcg
    17401 gggttgagcc ctcgcgtcgt ctcggtgtcc ggcccactcc tgagaagccg cgaggaggag
    17461 gccggacggt caacagccgc tcgctccgga ggagagggcg agcagccacc aaccagacaa
    17521 ctcgcttctg gggcctggtg gttagggcga ttcgccgtcc actccgagga aaggcctagg
    17581 atgatttgac tttcccttta cctggtggat gagggggcgt cagagctacc gttcgggcat
    17641 ggacaccacg cgcaacgccg ttctcgaggc gtggatggcc gaacacggct acagctccaa
    17701 cagcctcgcc gacgccgtga acggggccct cgagcggctg accggccggc ctggcggact
    17761 cgacggctcg tcggtccgag cctggaaggc gggccgtgtc atgtggccca aatcagccac
    17821 ccgcaaggcg atcgaggacg tcagcggcct gcccgccgtc gctctggggt tcgtgccacg
    17881 gggccggcct tcgtccaccc cctccccacc gcagcaggag gaccccgaca tgaagcgccg
    17941 caccctcgtc ggcggcatcg ctgctgccgc cgcagcagca gcggccgcgc caggcgccgc
    18001 agggccccgc cgcatcggca tgagcgacgt ggaccgcctg aacaagcgct tcgccgagat
    18061 catcgccagc gaccaccgac acggcggaca gctcggcatc gaacagcggg cggccgcgct
    18121 cgccgacgag gctctgaacc tgcagaacgc cggcagtgcc acccagcgcg tacgcagcaa
    18181 cctctacgcc tccgcggcgg cgttccgctc gtcggcgatg tgggccgcca tcgacggccg
    18241 ccgctacgac gtcgccaagg cgcacatgcg tgaggctcag gccctcgccg agatgtccgg
    18301 tgaccaggcc atcaagttcc gtatctggag ccacacgggc accatgtacc gccacatggg
    18361 ccggcccgcc gacgcgttcg ccgccaacga cgtcgcccgc aacctgtaca tcacgcgccg
    18421 cgacccgatg ttcgcttccc tcggcatggc ccggcatgcg gcgatccacg gcgcggcgca
    18481 cgaccgcacc ggcacccgcc gtgcgttcga ccaggcgcag gaagccatgc tgcgtgccga
    18541 ccccggcgac taccggcccg tatggctgct cgccttctac gaccaggccg agctgcactc
    18601 cctggccctg tccgcccatc tggcactcgg cgactactcg accgccgagt accacgccca
    18661 ccgctgcctc tccgccctgc ggccgcacat ggtccggtcc cggtccatca ccacgacccg
    18721 tctcgcgcac gcccagctcg cacagggtgc agccgacgcc gccacgagca ccgcgatgaa
    18781 ggtccccgcc gacgccgcca cccggcacgc ccgggtgacg cgcatgctgc aggagttcgg
    18841 ggccgcgctg cgcgccaccg cgccccgcag ctccaccgtg cagacctgga ccgagcacac
    18901 cgcctcctgg aggatggccg catgaccacg gcgcccgcca tcgaactgcg cacgttcacc
    18961 accctcgaca ccgcccgcgg cgacctcctc gacgtctacg ccgacgtgcg cgccccgctt
    19021 ctccacctgc ccaattacgc ggtcaccgcc ttcggcgagc gcctggaccg gcacggcggc
    19081 gagccgggat tcaccgcagt cctcgcctac gcggacgagc atccggtcgg atacgcctac
    19141 gccaacacca tcgagcacgg cgaccgctac tggcagcgca ccagcccggc gcctgcggcc
    19201 ccatacgccg agcgcccggc cgtggctctg aaggagatcg gcgtccggcc ggcgtggcgg
    19261 aagaccggca ctgcccggcg tatccacgac gccctcctcg ccacgcgcga cgaaccgttc
    19321 gtcacgctga tggtcaaccc ggccgccggg gacggaaagg tccacgctct ctaccggtcg
    19381 tgggggtacg aggacatcgg acagagccag ccgtcaccgg cgtcgccggt cctgactgtg
    19441 atggtccgtg ccgtgcgctg accggggcgc ggggcacggc agaacgctgc tgcgcgacgg
    19501 cgtcagcagt tgagcgcctc gtcgccatga gacggcaacc ctgcgggtgc ggggagcaga
    19561 tggctggcct ccagcgcgac gccgacgacc gggggccatc cctgcgggtg cagggagcag
    19621 ttcggcgctc acgggcgcac gtccttgccg ctgggaccat ccccgcgggt gcgaggagca
    19681 ggccaggccc gtacgtgctg ggggccgtga gcgggaccat ccccgcgggt gcggggagca
    19741 ggtggcgcgc tggtcggtgg tgatgggggc cgcgggacca tccccgcggg tgcggggagc
    19801 aggcgtcccc gtcgccggac cggcgcgcct ggtggggacc atccccgcgg gtgcggggag
    19861 cagtagccct ccggggctgg tcggccgtac tacgtgggac catccccgcg ggtgcgggga
    19921 gcagcggtac agcgtgaagc tggtggagcg gcctcgggga ccatccccgc gggtgcgggg
    19981 agcaggtcgt agcccggtcg attcgtgacg cggtgccggg accatccccg cgggtgcggg
    20041 gagcaggtcg gcatcggcgt ggacgaggtg accggcgagg gaccatcccc gcgggtgcgg
    20101 ggagcagtgg gtgagaggga tagcagaacg cgccggaggt ggaccatccc cgcgggtgcg
    20161 gggagcagaa gttcatgtgg gagtccgtcc tcaagccgct gggaccatcc ccgcgggtgc
    20221 ggggagcagt ccctttcgtg gattacccca tcgtcccgaa ggggaccatc cccgcgggtg
    20281 cggggagcag ggcacatcgg aaagctgaac atcaaggcga ccgggaccat ccccgcgggt
    20341 gcggggagca gactcaaggc ggcgggggtg accccgccgg ggggggacca tccccgcggg
    20401 tgcggggagc agggatccgc caactccggc caggcccacc gatggggacc atccccgcgg
    20461 gtgcggggag caggtggacg ccgggtacat cacggtgaac ccgctgggac catccccgcg
    20521 ggtgcgggga gcagactgtt cgacctgcga gtttatgacc gccgaagcgt gttctcaggg
    20581 actttaaggg attccggcaa atgaggcatt gcagccgatt acgtactggg gtcgagcggg
    20641 ctgcgtccta cgtcaacctc gcactgatcc gtgtcccgaa ggaacggtga tgacacgaca
    20701 acctcctcta ctcccattct cgcccaggac ggccgctccc acctgtaggg cctgtccttc
    20761 tggctcaaca ccgagcccta ggtggttatc cacagggcgc cctgcgttgt cttcaccgag
    20821 tgagacgatc tctgcctgac tgagcgagac atggagtatc ggagtgtcac taccagacac
    20881 gttgaagccc ttggacgcgt ccctggattc gacggaccgt gcccaggtca tggcagccgc
    20941 ctgggaagcc ttcgccgtgg ccgaacaggt ggcggacgct gtcgcttttg aggaagtcgg
    21001 cgacgagctc caggccctga tggccgcgca ggcgagtgcg gccggccgga gcctcctgcc
    21061 gctgcctggg ctcggtcgcc ccgtcgacgt gccgcccctg tcgcctggtg ccgaagggct
    21121 cgccccatac gtggagctac tgcgccacgt ccaggcggcc ctcgagcata cggctgccga
    21181 gccggggacg gaagaaggcg gccgagcggc ggtgcgggag gctgctgaca aagctgcaac
    21241 cgccgccggg gcgctcctcg ctacccggga gcgataggca tgcccaccac gctgagagag
    21301 ctgagcgaga ccgccagccg caacctgcgc gaggtcatct ccgacaccct catgccggac
    21361 gatgcccgag aacagtccgt cgtggtccga cagctgacca acctggtcag gcacctgcag
    21421 accgcactgg agagcgccgg ggagcggccc cggcgggcga accccgggcc cgccacccat
    21481 ctggccaccg cccagagcgc tctgcgccgc gcggccggac gattgcccgc cctcgacgac
    21541 gaggttgccg ccctgcacca cggcactccg ctggcccgtg cggtccaggc ggcggccgcc
    21601 gtacaggacc tcatcgccag ccatcgcggg cgggacggca tcccggtgac gccgtacgcc
    21661 ctggcgttca ccgaacgccc cgcccggtcc tacctggtgc actgctcggc ggacctggcc
    21721 tggggagcgg cccgagtggc tcacgcgttg ggcgaggccg tcaccaacga gggcaccgcg
    21781 gtgcagctgt acgtcgcgcg cggaagcctc gaccaagcct cggtgttcgg ccgcaccgcc
    21841 ggcggacaga tgaaccgggc tactgaggcg ttcccgcatg tgccgccgct cgatccccgc
    21901 ccggctctgc ccaccgatgc tcccgagagc atcaccgcgc atctcgccga cgactgcgag
    21961 cgcctgtccc gggttgcctt cgaggccctg cacggccgcg gcgagtccgg cttgagcggg
    22021 tccgacgtgc agcaactgac tcgatggcgg gcgatgagtg acctgctgtc cggccgtatc
    22081 ctgctgcacg tcgccacgtc cgtcgatccg cacaccgccg agccgctgcg ggaggccgcc
    22141 ggccggctgc gggagacggc acaggcctgg caagagagcg cggcgcagtg gcaccgggtc
    22201 gtcgatctct ccgaccctcg cgtccacccg aagctgccgc tgcccagcta ccacctcgcg
    22261 cgcagcggtc agttcacaca cctgcccaag acgcctccgc accccgccct gctcaccgcg
    22321 cactcgcata cgacacgcct cggtcagctg ctctacggca tggcctggaa cccggagaca
    22381 ccagggcgcc cggtccagcg cgacacccgg gaggtgcttg ccgacgccgg aggcctcgcg
    22441 gagctgacgc acacgatgta ccgggtggca gcttgccgcg gccatgccct ccgtcgtcag
    22501 gcggatcgaa tccactctgg tgaccgacaa cgtggatcac cgtcctccgg aggccgtgca
    22561 tcgcttctac ccgctgccca gccaccagac gagacgcctc gtagagcgct acgagcccgc
    22621 cgtgagggcc gagcaggcag ccgccgccag catcctgcgc acggctgccc gtacgggcat
    22681 ggacaccgcg cgcgcccggc tggacgcggc cgcccacaga cagatccggt ccggtcagcc
    22741 gtggctgccc gtcgacgtgg cggcggaaca gcagtcgggg cccacgctcc ccgcggcctc
    22801 gactgcccgc cccagtgctg cggcggcgcg cagccggtcg acaaccggca cccgttcccc
    22861 gagcacgaag cccacgacgt ccggtcctgt caccgcccac cggtccggcg acggcatcga
    22921 gcaccgcccc ggtcgcagca gatagccccg ggaaaggtga ggtgcttcac agcgcccaag
    22981 acattcctca cggtgcgcca cccggccggg cagccgccct cttcacccgc aaaccctcaa
    23041 gaggaaagtg accactccga tgttgaggaa gtggccgccc cgggcgaccg cccggccggg
    23101 taactctgcg caatggcagc caactcccat tgcgggaacg atgggttgac ggtcggtgcg
    23161 gtttctcatc cgggccgcta agtgactgtt tgagtaccaa agcacctgac cgtcgcgggg
    23221 tgttgtttca ggcggcggca ggcctctgcg ttgcttggac aggttcacca ggtcacctga
    23281 aagcggaaac acaactgcca ctttccgcac ttgagtgatc agtgacccga ccatcaccta
    23341 gagtcacacc agtgcaatcc gcactggtgt tccactggct tcaatcggcc ttggaggctg
    23401 ccgtgaatca tcactggcag aagttcttac aggtccccgt cgttgcgctt ctggcaacgg
    23461 tagctgcaac tacgccggca tccgctgagg atggtcccgc gccgctcacc agtccgacgc
    23521 gggcggcggc gcttgtggcc gagctcggcg gccaccgcac cggaggcgtg tactacgagg
    23581 atgggcgtct cgtcgtagcg gttactgatc aagcggcagc ccgaacggtc cggaatgcgg
    23641 gcggtgctgc gaaggttgtg acccgcagcg cagatgagtt ggcatccatc cacgacaagc
    23701 tcgaccaact gggaaacatc ccaaatacgg catggggtgt tgaagccgcc accaaccagg
    23761 tgaacgtcga gatcttcgac ggtgcacctt ctgatgctcg ttcccgaatc gagaagattg
    23821 cggctgccca cccgggcgcc gtagagatca gccggatcaa cagcaggttg gtgttcaagg
    23881 aacggctcct cggagccgtc ggcatcacat ccgatggatg gctgtgttct gccgggttca
    23941 acgccaagaa ctcgtcgggg gcaatctacg tactcaccgc cggtcactgc gtgccgggta
    24001 ccggcaacat ctggtacatg aactggaaca acgagaggat cggcgtccaa aacgcctacg
    24061 ccaacggcta cggcaccagc ggctggtgcg atggtgtaga ccgcggctgc gactgggcca
    24121 ccatccgggc agacggttcc acgatcaagc cggtcgaggg tgtccgatac ttcaacggca
    24181 ccgtcaagga catcaccacc tcccgattcg cggctgaacg ggaggactca gaccggatcg
    24241 gcaccatgag tgaggacacg acagggttca tcacgaagac aagcgtgacc gtcaacatca
    24301 gcggcaaaac catgcacggc atgtacgagt caaaccactg cgccctagga ggcgacagcg
    24361 gtgggccgct cttccacgga tcgacggctc tgggcctgct ctcagggggc actgccgaga
    24421 cgacctgcaa ctcctcgtct tccggcgagt accgcaacta ctacacgagg gtgcagacgg
    24481 tagtgaacga acgcggcctc cgcatctact gacgctatgc ctcagcggac cgtctccgct
    24541 ggagaaccta tcgtgcacca actgcgtcag aggtacgagc cgtcgccact ctgcagttct
    24601 ctctggaggt caccatgcgc atcaaggcca tgcactctgt cggcttgttg accacggtga
    24661 ctgtcgtcgg gctgaccgtc tccgcttgtg gcagtcagtc ggacgaaaag gctgaggccg
    24721 atgcaaaagc ggtgtcgcac cgcgccgagc aagtagccgc agcctgggat gggtcaaccg
    24781 cagccgacaa gtggcgtgct ggttactacc cgatgggtga tgtggttcag ttgccccatg
    24841 gtggtctgcg cagcaaagtt gatgagcagg catataagga ccgcagcttt gttctgcgag
    24901 gcaagttgcc caccgactgg ccaaaaagtg gccgggtgaa ttgggctggc gatgagtcgc
    24961 tcactcgccc cctgtcgggg gcggaggagt cgtacaggtc cctgtctggg gggctcgccg
    25021 acggcgagac cggcctcacg gtgactggcg cgaagctggg caccatgacg ctggccacca
    25081 gccgcggacc ggcgaccgtc cccgcctggc ttttcactct tgatggctac acctcccccc
    25141 tcaagagggc agctgccgac ccatcgcagc tccccccgtc accgatcggc cgagcgcgtg
    25201 acatccccgt acggcaactg aatgggctgg tcgacattgc cgaggacggg cgatcagtca
    25261 ctgtgatcgc tctccgtggt gtctgtcacg acggggcgac ggtggaggcc ctggaaaccg
    25321 tccgcagtgt ggtcctatcg tcctccgtca agcagcagaa ggacaatgag aagtgcacga
    25381 aacaggctag gttgcgacaa gtttcggtag aacttgagca ccccttgggg gaccgtattc
    25441 tgttggacgc gaagtcgggc cagccggttc cttacaaacc gccgtatgga ccctcaccaa
    25501 gctggagctg aatttctcga agtcgtccat ctcctgcgcc gtccaccgtg gcggccttgc
    25561 ctcatgcgac atgacgtctc ccctattctc cttcgggttg ctgcacaaca acacgcctgc
    25621 gggcaggtct gctgatccgt agtctccgcc gggcgggcac gggtctccgc ccgctcccaa
    25681 ccgttgtcag gaggacctca tgccgctccc gcccacgggc tggtacaaga gcagctacag
    25741 caccgacttc gaggaagcct gcgtggaggc ctgcgttgcc gcggttggcg ccggcgtact
    25801 ggtccgtgac gccaaggacc gcgatcgccg cccctttccc gtctctgccc ccgcatggag
    25861 cagcttcttg agcgcgctgc gccccgacgg cgtctgacca gacagccctc gtcgcgggac
    25921 catccccgcg ggtgcgggga gcagaaattc gtggccgcgt tcgtgccccg ccagcaggga
    25981 ctatccccgc gggtgcgggg agcagcggga tcagcaaggt agtgcgaact ggggtcaggg
    26041 actatccccg cgggtgcggg gagcagatct gcgcgtcgta ggcgctgcgg ttggcgtcgg
    26101 gactatcccc gcgggtgcgg ggagcagggg aggtagacga tgccgcccat cacgcacgcg
    26161 ggactatccc cgcgggtgcg gggagcagga gccgtcgcag cgggagcagg accggcaggc
    26221 gggactatcc ccgcgggtgc ggggagcaga tcatctgcgg gatcgtcacc gcaggatcag
    26281 cgggactatc cccgcgggtg cggggagcag gggaccgtgc ctaccccagc gctcggttcc
    26341 cggggactat ccccgcgggt gcggggagca gttgtag
//
