LOCUS       NZ_CP019724            21017 bp    DNA     linear   CON 01-JUN-2024
DEFINITION  Streptomyces pactum strain ACT12 chromosome, complete genome.
ACCESSION   NZ_CP019724
VERSION     NZ_CP019724.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces pactum
  ORGANISM  Streptomyces pactum
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Streptomyces pactum ACT12 Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8550793)
  AUTHORS   Xue,Q., Yan,X., Jia,L. and Yan,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2017) College of Life Sciences, Northwest A&F
            Unversity, No.22 Xinong Road, YangLing, Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2016
            Assembly Method                   :: SMRT v. 2.3.0
            Assembly Name :: version 2.3.0 of the PacBio Single Molecule Real
            Time
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002005225.1-RS_2024_06_01
            Annotation Date                   :: 06/01/2024 05:58:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,315
            CDSs (total)                      :: 7,221
            Genes (coding)                    :: 6,992
            CDSs (with protein)               :: 6,992
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 229
            CDSs (without protein)            :: 229
            Pseudo Genes (ambiguous residues) :: 0 of 229
            Pseudo Genes (frameshifted)       :: 84 of 229
            Pseudo Genes (incomplete)         :: 195 of 229
            Pseudo Genes (internal stop)      :: 15 of 229
            Pseudo Genes (multiple problems)  :: 62 of 229
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:20:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 250206
            Orig. end                         :: 271223
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP019724.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Northwest A&F Unversity.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21017
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21017
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21017
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11017](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11017)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(735..1196)
                     /locus_tag="B1H29_RS01000"
                     /old_locus_tag="B1H29_01015"
     CDS             complement(735..1196)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B1H29_RS01000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B1H29_01015"
                     /product="hypothetical protein"
                     /protein_id="WP_159027751.1"
                     /transl_table=11
                     /translation="MTTKGVPRTGLGRLTVSTITPYVVGAAVTGGAFLLFKDSFADVIA
                     THFTLDGASDGFHSPEAAFGLYLMIFGIEAAGSVAALLSIKDPRTGGSVAAFSWGLSAA
                     TAYLFVVVMQASTDLQGGAAQLPSYQLAIGVVVGLAAGGAAWLIGRRRA"
     misc_feature    complement(1352..1363)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.75"
                     /tool="antismash"
     misc_feature    1436..1451
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.33"
                     /tool="antismash"
     gene            2176..2736
                     /locus_tag="B1H29_RS37880"
                     /old_locus_tag="B1H29_01025"
     CDS             2176..2736
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013625.4"
                     /locus_tag="B1H29_RS37880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01025"
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="WP_063787552.1"
                     /transl_table=11
                     /translation="MSLRSGRAIAVTLAFLSLGGLAVSATPAAASPSAGVVTGAGLPFD
                     DFGDEGPVSASSHAHSNLAAMWQAILWADASYEQNGTPFDLSDIDCRFGPNTTYATKRW
                     QARFGLARDGIVGPNTFGALGPWSGSSSGGVEYFTYHGENAAGNATGREVAFRRNAAGE
                     VAMWNQGDLKKLWYNSATFDSCS"
     misc_feature    2182..2184
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3870..5555
                     /locus_tag="B1H29_RS01020"
                     /old_locus_tag="B1H29_01035"
     CDS             3870..5555
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006382950.1"
                     /locus_tag="B1H29_RS01020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01035"
                     /product="ribonuclease J"
                     /protein_id="WP_055421569.1"
                     /transl_table=11
                     /translation="MSHPHPELKAAPPLPDGGLRVTALGGLGEIGRNMTVFEHAGKLLI
                     VDCGVLFPEENQPGVDVILPDFTSIRGRLDDVVAIVLTHGHEDHIGGVPYLLRERSDIP
                     VVGSKLTLAFIEAKLKEHGIRPRTVLVREGDRRGFGPFDCEFVAVNHSIPDGLAVALRT
                     GAGLVLHTGDFKMDQFPLDDRITDLRAFARLGEEGVDLFLTDSTNAEVPGFTTSERELN
                     PAIEQVMRTAPRRVIVSSFASHVHRIQQVLDAAHQYGRKVAFVGRSMVRNMGIARELGY
                     LRVPPGLVVSTKELEKLPDHKVTLVCTGSQGEPMAALSRMANRDHMIRVGKGDTVLLAS
                     SLIPGNENAIYRVINGLTRWGANVVHKGNAKVHVSGHASAGELVYCYNIVKPRNVMPVH
                     GEFRHLRANADLAIRTGVDPKRVVVAEDGVVVDLVDGRASISGKVPAGNVYVDGMEVGG
                     ATEASLKDRLTLAEEGVVTVVALVDADTGALTEPPDFLARGFVHDETTFEPVIPLIEKT
                     LATAAQEAVGDARQLEQLIARAVANWAFRTHRRRPLVIPVIIDA"
     gene            5653..6369
                     /locus_tag="B1H29_RS01025"
                     /old_locus_tag="B1H29_01040"
     CDS             5653..6369
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129070.1"
                     /locus_tag="B1H29_RS01025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01040"
                     /product="hypothetical protein"
                     /protein_id="WP_055421568.1"
                     /transl_table=11
                     /translation="MSLRFEEIDWRETPIGDISLRRRRHPATGEDVYEVKLGDEFLMSS
                     LFTAGEIALAELGLANLPDTRLDVAVGGLGLGYTARAALDDPRTNTLTVIDALAEVIDW
                     HQRGLVPLGAALASDVRCRMVHGDFFTMATEPGGLDPTMPGRRFHAVLLDIDHSPSHVL
                     NPRHAAFYRPAGLRALATHLHPDGVFALWSNDPPDEQFVSALADAFAAPEAHVVSFDNA
                     LQDGNATNTVYVAHKK"
     gene            complement(6695..7246)
                     /locus_tag="B1H29_RS01030"
                     /old_locus_tag="B1H29_01045"
     CDS             complement(6695..7246)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981982.1"
                     /locus_tag="B1H29_RS01030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01045"
                     /product="hypothetical protein"
                     /protein_id="WP_055421567.1"
                     /transl_table=11
                     /translation="MDTVVATPAPAAGAAVTLRRLYLLRFAFAAVWAGLLWTAHDVLGV
                     LSGTLLVLYPLFDVACAIVDVRSARAVRGPVRVLYVNIALSVLTATGLIAAVSSGIPAV
                     LRLWGAWAITAGLVQLIVGVLRRSMGGQWPMIASGGISALAGASFIAQAAQDDPTLTAL
                     AGYAFLGGVFFLISALRLRR"
     misc_feature    complement(7362..7375)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.69"
                     /tool="antismash"
     misc_feature    7410..7423
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.69"
                     /tool="antismash"
     gene            7452..8048
                     /locus_tag="B1H29_RS01035"
                     /old_locus_tag="B1H29_01050"
     CDS             7452..8048
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056564.1"
                     /locus_tag="B1H29_RS01035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01050"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_055421566.1"
                     /transl_table=11
                     /translation="MSASTGGGKTSEARSRLLGTATRIFYTEGIHSVGVDRITEEAQVT
                     RATLYRHFKGKEDLVLAYLQQADQGIRGQVEAVRAQRLPAHDTVRAVSRTITEGIRSSG
                     FRGCAFLNAAAEYPDPAHPVHQAVLAHRQWFLETAIELLAQAGCVPADAAGRHFVMLRD
                     GAMAAGCLFNPALISETFLHGVEGILPPEPARKPG"
     gene            8065..>8199
                     /locus_tag="B1H29_RS39000"
                     /pseudo=""
     CDS             8065..>8199
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140768.1"
                     /locus_tag="B1H29_RS39000"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGERRAYPSDLPDSRWELAEPVLTAWRAEPRRHALDIARPPEPEV
                     "
     gene            complement(8459..9355)
                     /locus_tag="B1H29_RS01040"
                     /old_locus_tag="B1H29_01055"
     CDS             complement(8459..9355)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057889.1"
                     /locus_tag="B1H29_RS01040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01055"
                     /product="hypothetical protein"
                     /protein_id="WP_063787551.1"
                     /transl_table=11
                     /translation="MNRHLALLATATRYNLVEHVRNRFAMLLVVLYIPTWVTLCYLNIP
                     DEPMPYRLRDTGRVLSLPGNELTQLSGAINAVTLITGFMMFAATFAGGRFDRRLAMAGY
                     PRTHLAVAKIISLTLASATVAAYATAVMWPAWHARRPVLLATALFGDAMTYGTLGVIFG
                     SVFRREVEGMFAMLMTSVIDIALQSPLANSGVDSTFVRFLPSWGAMQAAVAAGYSDDSV
                     FVYGTVQLAWFTTTAVLALLAFHHRTRNALPKAGPPLTDLLPPINTRTTCPPSLRHPAI
                     RGLPEPRLTGAPEADDG"
     gene            complement(9352..9981)
                     /locus_tag="B1H29_RS01045"
                     /old_locus_tag="B1H29_01060"
     CDS             complement(9352..9981)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385751.1"
                     /locus_tag="B1H29_RS01045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01060"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_199832443.1"
                     /transl_table=11
                     /translation="MRFENGTTLLVRGLCHAYGRRAVLRGVDLTVRAGALVGVVGENGT
                     GKSTFLKILSGELRPQRGSVRREGRFGYCPQDAVLNDALTVRQHLEFFQAAFALPDLRY
                     AEEIMEVLGFSEYADQRAGLLSGGTRQKLNLTLALMRDPRLLLLDEPYQGFDWETYQRF
                     WHLAARLRDAGRSVLVVSHLAYDAERLDELWRLEDGLLRSTREVSA"
     gene            complement(10001..11017)
                     /locus_tag="B1H29_RS01050"
                     /old_locus_tag="B1H29_01065"
     CDS             complement(10001..11017)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="B1H29_RS01050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01065"
                     /product="terpene synthase family protein"
                     /protein_id="WP_055421565.1"
                     /sec_met_domain="T1TS (E-value: 2.2e-47, bitscore: 161.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAEQSGVEGLVLDLPLGGTILPLDRVNPQHAHLREAHDRWFAD
                     RLIGRQRDKVLDRIKRHDMAGLATRAAPSADVGYLLDAALFTTTGFIVDDELEDPDTPP
                     RLIDAYLAVADESDTAVDSDDLRLWADSLAQTRSHLTPGQKTRHCRGLSEWVKCHAGRE
                     GQLEHTRDLASYLDFRRADSGFSFLTVGVERSAGVDLEQMMHSSDLETLHAACLAHGTL
                     VNDLFSYRKERDAPVPMNAVPVLQRAEGLTLQAAVDKVCGLIRRAELDVDRLVRKWKET
                     DRAQALYAYAHAWWELLGGHLRWTMESERYHGRGHVWDGTFPTAMVLYPDRTVLVSA"
     gene            complement(11624..12202)
                     /locus_tag="B1H29_RS01060"
                     /old_locus_tag="B1H29_01075"
     CDS             complement(11624..12202)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981641.1"
                     /locus_tag="B1H29_RS01060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01075"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_055421564.1"
                     /transl_table=11
                     /translation="MSVQERKERERASRERLIVATARELAEQQGWDAVTTRRLAERIEY
                     SQPVLYSHFRGKREIIGAVALEGAAEMAAALRAAASAADGPRARVTALARAYLDFAERN
                     PAVYDAIFQLDGGLAFARADTPEPLKDAFAALLESLGEVAGDGVHPGLFTEVFWAALHG
                     LATLTREGRLPPEDTERRTELLVDRLAML"
     misc_feature    complement(12185..12196)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            12294..12740
                     /locus_tag="B1H29_RS01065"
                     /old_locus_tag="B1H29_01080"
     CDS             12294..12740
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003676.1"
                     /locus_tag="B1H29_RS01065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01080"
                     /product="DUF1772 domain-containing protein"
                     /protein_id="WP_055421563.1"
                     /transl_table=11
                     /translation="MLNALEVFTTVVVGVMVGVEFSVAFVVNPILDGLPDDCGQRGRAH
                     GGRMLGAVMPVWYITSLVLVAVWAAAGWHHPGTGLVVTAGALLILSVIMSILLLVPINN
                     RGKTWTPDNRPDDWKQQMNRWDRYHYVRVAVIIAAFALLAAALT"
     gene            complement(<12846..>13125)
                     /locus_tag="B1H29_RS39005"
                     /old_locus_tag="B1H29_01085"
                     /pseudo=""
     CDS             complement(<12846..13125)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612357.1"
                     /locus_tag="B1H29_RS39005"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="B1H29_01085"
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDDPGREARRSTRRRRELRPRVALLRRSRGGWTSEVHLAADRGCR
                     PPAFVQTAGQTAVGPRFIPVLDQVCVRGPVGRPRTRPGRGRRGQGAFV"
     gene            13474..15669
                     /locus_tag="B1H29_RS01070"
                     /old_locus_tag="B1H29_01090"
     CDS             13474..15669
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019328261.1"
                     /locus_tag="B1H29_RS01070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01090"
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_055421562.1"
                     /transl_table=11
                     /translation="MPTVGIPPAAPVSRRPGRRGLVGVLVTALAAALLAVVPATRAQAA
                     PALLSQGKPVTASSQEHYGTPAAAAVDGDDGTRWSSAAADPQWIRVDLGAPASLSRVEL
                     RWEAAYATSYRIETSQNGSAWSTAYSTTTGTGGTETVNVSGTARYVRMLGTARATGYGY
                     SLWEFKVYGTTGDDSGPVIPGGGDLGPNVHVFDPSTPGIQAKLDQVFEEQESAQFGSGR
                     HAFLFKPGTYDNLNAQIGFYTQVLGLGLRPDDTTINGDITVDAGWFNGNATQNFWRGAE
                     NLAVKPVSSTNRWAVSQAASFRRMHVKGGLNLAPNGYGWASGGYIADSKIDGQVGNYSQ
                     QQWYTRDSSIGGWSNSVWNQVFSGVEGAPATSFPEPRYTTLDTTPISREKPFLYLDGNE
                     YKVFAPAKRTNARGTTWAGGTPQGESIPLSEFYVVKPGATAATINSALAQGLHLLFTPG
                     VYHVDQTINVNRADTIVLGLGLATIIPDDGVTAMRVADVDGVKLAGFLIDAGPVNSPTL
                     LEIGHQGASTDHAANPTTVQDVYIRIGGAGAGKATTSMVVNSHDTIIDHTWVWRADHGE
                     GVGWETNRADYGVRVNGDDVLATGLFVEHFNKYDVEWYGERGRTIFYQNEKAYDAPDQA
                     AIQNGATKGYAAYRVDDSVDTHEAWGLGSYCNYNVDPDIRQDHGFRTPVKPGVKFHSLL
                     VVSLGGMGHYNHVINDTGASTVPAGTTTVPSTVVSFP"
     gene            15796..17964
                     /locus_tag="B1H29_RS01075"
                     /old_locus_tag="B1H29_01095"
     CDS             15796..17964
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123982.1"
                     /locus_tag="B1H29_RS01075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01095"
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_055421561.1"
                     /transl_table=11
                     /translation="MSTALPYRRPVRRAGVPLLALGALVASSLAVAAPPAQAAEALLSQ
                     GKPATASSQEGDGYAASAAVDGDLTGTRWASRWSDPQWFQVDLGQRADLSRVVLTWEGA
                     YAKSYQIQASDNGTQWRTLKTVSGGDGGTDEVAVTGAGRYVRMLGTERSGGYGYSLWEF
                     QVYGTAEGTPPADGGAVKVAGTQGNWHLTVGGQPYTVKGLTWGPAIADAPKYMPDVKSM
                     GVNTIRTWGTDGGTKPLLDSAAANGIRVVNGFWLQPGGGPGSGGCVDYVTDTTYKNNML
                     TEFAKWVEAYESHPATLMWNVGNESVLGLQNCYSGSELEAQRNAYTSFVNDVAKKIHSI
                     DPDHPVTSTDAWTGAWPYYKRNAPDLDLYSMNSYGDICGVREDWEEGGYTKPYIITEGG
                     PAGEWEVPDDANGVPDEPTDVQKAEGYTKAWDCVTGHRGVALGATLFHYGVEHDFGGVW
                     FNLVPDGLKRLSYYSVKRAYTGSTTGDNTPPVITNMAVSPASSAPAGGEFTVRADVRDP
                     DGDPVTYKVFLSGNYATGDKRLVEATWRSTGDGTFAVTAPEKLGVWKVYIQAEDGRGNA
                     GIETKSVEVVAPPVSGTNVALNKPTTASSFQPSYGDCPCEPAKATDGKNDTRWASDWSD
                     PQWIQVDLGAATPVRKLQLVWDPAYAKSYEVQVSDNGTTWRTVHTTTAGNGDVDTIDMA
                     QTARHVRLHLTARGTGWGYSLHEFGIYG"
     gene            18146..20578
                     /locus_tag="B1H29_RS01080"
                     /old_locus_tag="B1H29_01100"
     CDS             18146..20578
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523046.1"
                     /locus_tag="B1H29_RS01080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B1H29_01100"
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="WP_055421560.1"
                     /transl_table=11
                     /translation="MDDEALDRLIGKLSLEQKVRLLTGATTWRTAGESGIGLREMVTSD
                     GPAGVRGEAWDERRSSALLPSASALGAMWDEELVERLGGLLAREAIRKGVDVVLAPTLN
                     LHRSPLGGRHFECFSEDPRLTGRTGAALIRGVQALGVAATAKHYVGNDSETDRLTVDVR
                     ASERTLREVYLLPFEAAVEAGVWVVMAGYNAVGGTTMTASPLLAEPLKGDWGFDGVAVS
                     DWAAVRSTEEPGRAALDLAMPGPDSPWGANLVRAVKDGRVAEEAVDEKVRRLLRLAARV
                     GALEPHHPRRAPATAARATRALLRRAVSAGSVLLRNDAVLPLDSAELSTVAVIGVHAAS
                     PRVQGGGSAGVFCSDVVTPLAGIRSRLRGRARVVYEPGPAPGAPPAPLGTDRCCDPRSG
                     APGVLLRVLDAAGRELRAEHRLSGRQLEPDLPPGARTVEIAAVLRPRQSGEWTFGAGGF
                     GRITLTVDDHVLLDGEFPGDTDDPAVVHVNPPVHTVRTVLTTQRPVHVVARRELVPGRG
                     RATVVTAAPPGPSPATALEEAVRAARDADAAIVVVGTTEHSETEGYDRAGLSLGGHQDE
                     LVRAVTAANPRTVVVVNSGGPVELPWREEAGAVLLTWFPGQEAGAGLADVLFGHTEPGG
                     RLPTTWAATLADAPVTRTRPVDGRLDYAEGLHIGYRAWLRAGREPAYWFGHGLGYTTWA
                     YAAVEAPAHVLADEPFTVRVTVRNTGSRAGREVVQVYLARPGSAVERPVRWFAGHAAVR
                     AEAGRTASAEVVVGPSALRHWSEADHGWATEPGAYRLMVGRSAGDLRWEGTVTVSGP"
     misc_feature    complement(20812..20821)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 gaggctctga tccgcaagcc ctcctacggc gcgttctacg acaccccgct cgacacgatg
       61 ctgcgcaacc tcggccgcga cacggtcatc gtcacaggca ccctcaccaa ctactgctgc
      121 ggcaccacgg cccggcaggc atacgaacgc ggctacaagg tcatcttcgg atccgacacc
      181 acggccaccg acgacgagtc ccgccaggaa ccagaactcg ccgtcctgcg caaaggcttc
      241 gcactcgtgc tgaccgccga ggagatcacg aaccgactga tcgcaaccgc ggcagcaccg
      301 taggacgggg ccaaggcgaa cgttgcctga tgcagcacta gctgatgagt tcgccgtcgt
      361 acgtgccgcc ctcgcaatgc atgacggcga tggtcccggg catcggcaag gtgctgaacg
      421 tgggggtgcc tccaccgttg atgcatttcg cttggaggcg tcccgacctc ggcccgggcg
      481 ggccctggcc aggagaggga acgacgcgga agccgcggtc acgccgctcg gcgagaccgt
      541 gatggtgacg gctccggtgg cccggaaggc ggcggggacg atcaacagcc agagtgccca
      601 ggggccggtg cgcgccgacg aggacggcga tgactagtag gccgatcgtg gcaaccgcgc
      661 cggtcgcgag agcatccagc cggatgtcac ggagcggtgc cagacggcga cggtgccgcg
      721 tctcggaggc cggttcacgc gcgtctccgc ccgatcagcc acgccgcgcc tcctgcggcg
      781 aggccgacga cgacgccgat ggcgagctgg tacgacggga gctgagccgc cccgccttgg
      841 aggtcagtac tggcctgcat caccaccacg aagaggtagg ccgttgcggc agacagaccc
      901 caggagaaag ctgccactga acctcctgtc cgagggtcct tgatcgaaag gagcgcggcg
      961 acggaacccg cggcttcaat accaaatatc atcagataca ggccaaatgc ggcttccgga
     1021 gagtggaatc cgtcgcttgc cccgtccagc gtgaaatggg tggcgatcac gtccgcgaag
     1081 gagtccttga agagtagaaa ggccccgccg gtgacggcgg ctcctacaac gtaaggggtg
     1141 atcgtcgaca cggtaaggcg tccgagtccg gtgcggggca ctcccttggt cgtcatgtgc
     1201 cgcccatccc ttctgtgtac cttgcaggcg atctgatcgt tcgcctgcaa ctagaacatc
     1261 tccgagggcg ttccaggatt tccgtgtgtg atgtgtgacg gtcggagaac ggctcaatcc
     1321 tgcgcatcga tgactcgtcg ccccagaaat cgataccgct ttcgggcgtc gctgttagcg
     1381 cgttggcgtc cgtgatcgca gtatcgcggg cagtgaccat ccatctagga cggaaggtta
     1441 cacatgcaca gacgcgcagc tctagccgtg gcgggcgtcg ccgtgctcgc cgctgagcgg
     1501 ctcggcaagc ggtgacctgt cgaccatggc gacgccgacg catccggggc cggagcagtc
     1561 tcgggttcgg actgagacgc tgcggtcgtc ggaacacaca ggcagcggcg gtgctgggca
     1621 acactccgtt cggcggctcc gctcatgttg tgccagaggc gccaccggtc ggcgacctgg
     1681 accgtctgcg gcgctccggc ggcggcgcct tcggcgacga tcggcgcgct gggtcccggc
     1741 agacgacctc aacgccaggt cgttggacga gccaggcggc caaactggag gcctcccggc
     1801 ccgggagagg tcgatcggcc gacgggtttc gatgtccacc agcacggtgc cgtagtggcg
     1861 gcccttgcgg gtggcgtact catccacgcc gaccacccgc cgcgcgggcg cctccggctc
     1921 aggcagggca tcgcccacgc gcaggacccg tgctccggcg gcatggggca cggcctgccc
     1981 gcgcgactga gcgggcggcc tgacacatac cgcggtggtt gtacgacgcc ccctcctgcc
     2041 gccgtagttg acgcgcggtt caacctgacg tgtgacgcgc tctgtgcccc gagcccatat
     2101 agtccccgga cgacgcgcgg ggttggtgag gggccccacc gaggtcccgg tgccgcgcgg
     2161 aaatggaggc aacgaatgtc gttacgcagc ggccgagcaa tcgctgtgac cctggccttc
     2221 ctgtccctcg gcggcctcgc cgtgtccgcc accccggctg cggcctcccc gtccgccggc
     2281 gtcgtcacgg gcgcaggact ccccttcgac gacttcgggg acgagggccc ggtgtcggcc
     2341 tcgtcgcacg cgcacagcaa tctggctgcc atgtggcagg cgatcctgtg ggctgacgcg
     2401 tcctacgagc agaacggcac tcccttcgac ctgagcgaca tcgactgccg gttcgggccg
     2461 aacaccacgt acgcgaccaa gcggtggcag gcacgctttg gcctcgcccg cgacggcatc
     2521 gtcggcccga acaccttcgg ggcactgggg ccctggagcg ggtccagcag tggaggcgtg
     2581 gagtacttca cgtaccacgg agagaacgcg gccgggaacg ccacgggccg cgaggtcgcc
     2641 ttccgccgga acgccgccgg tgaagtcgcg atgtggaacc agggcgacct caagaagctc
     2701 tggtacaact ccgccacgtt cgactcgtgc agctgacccc gtactgacct cgcctctcag
     2761 tcagcgcagg tgggccccga agggcggcga aggctgctcc caccgccgtc acggtgggag
     2821 cggcccccgt ccgctcacca ggtggaacag cagccaggca gtcacggagt acacggtgca
     2881 cgccagaacc gcccgctcgg tccgggccag gcagatcagg acgagacgct gggagacggc
     2941 actcccgccg tcgtacacgc ggacggtccg ttctccacgg ccagttccct gatgatgacc
     3001 tcagaccccc gatggccgtg cccctccggt gtgacggtga aggtgaagca ccctgtcaca
     3061 agtgtctcgc tggtgaggaa gactcccggt ccgacgccca gcagctctgc cgtcactatg
     3121 acgtcaggac catgccgctc gatcctgacc aggccctgag ccggctttcc acgagggaaa
     3181 gcccgagcta tctcgccgtc gtccagcaca ccgtcagccg ccgccccgac gagcttctcc
     3241 tgccgagtct cagcaccgct ccgcagattg gcgcgggctt ctccctcggc acggtcatcc
     3301 gccgtggccg cccagaccca aagtccgatg ctgcacacaa gaagcagcgt gagtacagcc
     3361 aggcaaccgt tgaggacaca ccctccagcc gttccactct gcaccccgtc gcgtcttccc
     3421 atgatccgag catgccggtg cctggaccgc ttaggaggtg cgagtccaag ctgttactca
     3481 ttccgcccct gcccgaaacc aggcaccccg agctcacttg ttcgaggctt cttccggagg
     3541 gaactgccca tgccagcatc cacggcccac ccggcgtgcg taccgtgagg tgacgacccg
     3601 ccgccgggag gaccggccga tcagcgcgca gcccgaccac gtccccgccc cgccgcacgc
     3661 ccccgcgccc ggggcgccag ccgaactcct cgcccggcgc gcggaccggg gggggcgccg
     3721 gccttcgaac gggacggctc ggtgttcctc ctccgacagg acacgacttc ggtgatcctt
     3781 cgcgtccgag tcactccggt ccgcacgccg ctccacccgt ccgggcaggc cgtgaagacc
     3841 ttcgggggac tctccgatag cgtcaggata tgagtcatcc gcatccagaa ctcaaagccg
     3901 ccccgccgct gcccgacgga ggactgaggg tcaccgctct aggcggtctg ggcgagatcg
     3961 gtcgcaacat gaccgttttc gaacatgccg gcaagctgct gatcgtggac tgcggcgtgc
     4021 tgttcccgga ggagaaccag cccggcgtag acgtgatcct tcccgacttc acatcgatcc
     4081 ggggccgcct ggacgatgtc gtggccatcg tgctcactca cggccacgag gaccacatcg
     4141 gcggcgttcc ctacctgctc agggagcgtt ccgacattcc cgtcgtgggg tcgaagctca
     4201 ctctcgcctt catcgaggcg aaactgaagg agcacggcat caggccccgc acggttctgg
     4261 tacgggaggg cgaccggcgc ggcttcggcc ccttcgactg cgagttcgtg gccgtcaatc
     4321 attccattcc ggacgggctc gcggtcgccc tgcggacggg cgccggcctg gtgctgcaca
     4381 ccggcgactt caagatggac cagttccccc tggacgaccg catcaccgac ctgcgggcgt
     4441 tcgcgcgcct cggtgaggag ggtgtcgatc tctttctcac cgactccacc aatgccgagg
     4501 tgcccgggtt caccacgtcc gagcgggagc tgaacccggc gatcgagcag gtgatgcgca
     4561 ccgcgcccag gcgggtcatc gtctccagct tcgccagcca cgtacaccgc atccagcagg
     4621 tcctggacgc cgcccaccag tacggccgca aggtggcatt cgtcggccgg tcgatggtcc
     4681 gcaacatggg catcgcccgc gagctgggct acctccgcgt cccgcccggc ctcgtggtca
     4741 gtaccaagga gctggagaag ctgccggacc acaaggtcac cttggtctgt acaggctccc
     4801 agggcgagcc gatggccgcg ctctcccgga tggccaaccg cgaccacatg atccgcgtcg
     4861 gtaagggcga caccgtcctg ctcgccagct ccctcatccc cggcaatgag aacgccatct
     4921 accgggtgat caacggcctc acccggtggg gcgccaacgt cgtccacaag ggcaacgcca
     4981 aggtgcacgt ctccggtcac gccagcgccg gcgagctcgt gtactgctac aacatcgtca
     5041 agcctcgcaa cgtcatgccc gtgcacggcg agttccggca tctgcgggcc aacgcggacc
     5101 tggcgatccg taccggcgtg gacccaaaga gggtcgtcgt cgccgaggac ggtgtcgtcg
     5161 tcgacctcgt cgacggccgc gcctccatca gcggcaaagt ccctgcgggc aacgtgtacg
     5221 tcgatggcat ggaggtcggc ggcgcgaccg aggcatccct caaggaccgc ctcaccctcg
     5281 ccgaggaggg cgtcgtcacc gtcgtcgccc tcgtggacgc cgacaccggc gcgctgaccg
     5341 agccgcccga cttcctggcc cgtggcttcg tacacgacga gaccaccttc gagcccgtca
     5401 tccccctcat cgagaagact ctggccaccg ccgcgcagga agccgtcggt gacgcacgcc
     5461 agctcgaaca gctcatcgcc cgcgccgtcg cgaactgggc gttccgcacc caccgccgca
     5521 ggcccctcgt catccccgtc atcatcgacg cctgacaagg ccgcgtttcc gctccgcccg
     5581 cgggccggcc gtgcccggca ccgtcccggc ggcgccattc ttcagagcac cgaacgtcag
     5641 gaaggtgaac ggatgagctt gcgtttcgag gagatcgact ggcgggagac gccgatcggt
     5701 gacatcagtc tgcgaaggcg ccgccatcct gcgacgggcg aggacgtcta cgaggtgaaa
     5761 ctgggcgacg agttcctgat gtccagcctc ttcaccgccg gcgagatcgc gctggccgag
     5821 ctgggactgg cgaacctgcc ggacacccgg ctggacgtgg ccgtcggcgg actcggactg
     5881 ggatacaccg cccgggcggc gctggacgat ccccggacaa acacactcac ggtgatcgac
     5941 gcactcgccg aagtcatcga ctggcaccag cgcggcctgg tccccctcgg cgccgcgctg
     6001 gcctcggacg tacgctgccg aatggtgcac ggcgacttct tcacgatggc caccgaaccc
     6061 ggcggcctgg acccgacgat gcccggccgt cgtttccacg ccgtcctgct ggacatcgac
     6121 cactcaccga gccatgtgct caacccccgc catgccgcct tctaccggcc cgccgggctc
     6181 cgtgctctgg caacgcacct ccaccccgac ggagtgttcg ccctgtggtc gaacgacccg
     6241 ccggacgagc agttcgtctc cgccctcgcg gatgccttcg ccgctccgga ggctcacgtc
     6301 gtcagtttcg acaacgccct ccaagacggc aacgcgacca acaccgtgta cgtggcgcac
     6361 aagaagtagc cgtgtccgct caatcggaga ggggggagag gggctctcgt gcccgttgta
     6421 cgacggccgt gaggatctcc ccagccagag gaacgccgac ggcgacacca agttcgacct
     6481 gtggtcatcg gcgcccaagg cccgacgtcg cgaacggcgc ccagatggct cctgccggaa
     6541 tgccggggca gcggtctcgg ccggcggcga gggcagcggc aggcacggcc actggtgcct
     6601 gaccgcgtct gcttcggcgc ccgggttgca caggcgatgc ggagcaggtg ggtcgggccg
     6661 cgctgttgtt cgcggcccgg ccccctcctc cttgtcagcg ccgcaggcgc agtgcagaga
     6721 tgagaaagaa gaccccgccc aggaaggcgt atccggccag agcggtcagg gtggggtcgt
     6781 cctgcgcggc ctgtgcgatg aatgaggccc cggccagggc ggagatgccg ccgctggcga
     6841 tcatcggcca ctgtcccccc atgctgcgcc gcaggacacc gacgatcaac tggacgagac
     6901 ccgcggtgat ggcccaggca ccccacaggc gcaggacagc cgggatgccg gaggagacgg
     6961 ccgcgatcag ccccgtggcg gtcaggacac tgagcgcgat gttcacgtag agcacgcgca
     7021 ccggccctcg gacggccctg gcggaccgta catcgacgat cgcgcaggcc acgtcgaaca
     7081 acgggtagag aaccaacagc gttccgctga ggacccccag gacgtcatgg gccgtccaca
     7141 gcaggccggc ccacacggcg gcgaacgcga agcggaggag gtacagacga cgcagcgtca
     7201 cggcagcgcc cgcagcgggg gcgggggtgg caacgacggt gtccatgagg agtcctttcg
     7261 ggaaagcggc acgccgcggc aaggcagggc agggagacac gcggcctgac tgacggagac
     7321 gtgaccatgt cctcgcccag agccacagag ccgggagagg gagaacgttc ggtctctctt
     7381 catctaaagc cgctcacagc cagccgtcaa gaccgaacgt tctccctcag acacctgata
     7441 cggtgggttc catgagcgcg agcactgggg gcggcaagac gtccgaggcg cggtcacggc
     7501 tgctcggcac ggcgacccgc atcttctaca ccgagggaat ccactctgtc ggagtggacc
     7561 ggatcaccga agaggcccag gtcacccggg ccactctgta ccggcacttc aagggcaagg
     7621 aagacctcgt cctcgcgtac ctccaacagg ccgatcaggg catccgaggc caggtcgagg
     7681 cggttcgcgc ccaacgactc cccgcccacg acacggtccg ggccgtcagc cggacgatca
     7741 ccgagggcat ccggtcctca ggtttccgcg ggtgcgcctt cctgaacgcg gcagccgagt
     7801 accccgaccc ggcgcatccg gtccaccagg ccgtgctggc gcatcggcag tggttcctgg
     7861 aaaccgccat cgagttgctc gcacaggccg gctgcgtgcc cgcagacgcg gcgggccgtc
     7921 acttcgtcat gctccgggac ggcgccatgg ccgccggctg cctcttcaac cccgcactca
     7981 tctccgagac atttctgcac ggagtggaag gcatcttgcc ccccgagcct gcgcgcaagc
     8041 cgggctgagg ggtctgtcca ggccatgggg gaacgtcgtg cgtatccgag tgatctgccc
     8101 gattcccgct gggagttggc cgaacccgtt ctgacggcct ggcgggccga gccacgtcgg
     8161 catgccctgg acatcgcgcg gccgcccgag ccagaggttg ctgtcacgtc ttcccgaccg
     8221 gactgggcgg cggtcggtcc gggatcccgt acctctgctt ccacgccagc tcctgttcgg
     8281 tgactgacgc cccggatcgg cggcgcagag ggttgcggcc atggtgtggg cgcgcgggtc
     8341 cccgggtgga gccaccctcg gccggtggag ccgtggcggc aagagccgag ggcggcgagg
     8401 gcccggggaa gaccctcatc cgcgccttcc gccgcgccga ctgctctctg gcgttgcgtc
     8461 agccgtcgtc cgcttcgggg gcgccggtca ggcgcggctc gggcagtccg cggatcgccg
     8521 ggtgtcggag gctgggcggg caggtcgtcc gggtattgat gggcggcagt aggtcggtga
     8581 gaggcggccc ggccttgggg agggcgttgc gggtgcggtg gtggaatgcg aggagggcca
     8641 ggacggccgt ggtggtgaac caggcgagtt ggacggtgcc gtagacgaac acggagtcgt
     8701 cggagtaacc ggcggcgacg gcggcttgca tcgcgcccca ggagggcagg aagcggacga
     8761 aggtgctgtc gacaccggaa ttcgcgaggg ggctttgcag agcgatgtcg atgacgctgg
     8821 tcatgagcat cgcgaacatg ccctctactt cccggcggaa gacggagccg aagatgacgc
     8881 cgagcgtgcc gtaggtcatg gcgtcgccga agagcgcggt ggcgaggagg acgggccgac
     8941 gcgcatgcca ggcgggccac atgaccgcgg tggcataggc ggcgaccgtg gcggaggcga
     9001 gggtcagtga gatgatcttg gcgactgcca ggtgcgtacg ggggtagccg gccatggcca
     9061 gacgccggtc gaagcgtccg cctgcgaagg tggcggcgaa catcatgaat ccggtgatca
     9121 gggtgacggc gttgatggcg ccggagagct gggtgagctc gttgcccggc agtgacagca
     9181 cccggccggt atcccggagc cggtacggca tcggttcgtc agggatgttg aggtagcaga
     9241 gtgtgaccca ggtggggatg tagagaacca ccaggagcat ggcgaaacga ttgcggacgt
     9301 gctcgacgag gttgtacctg gtggcggtgg cgagcagggc caagtgtcgg ttcacgcgga
     9361 cacctcccgg gtggagcgca gcaggccgtc ctccaggcgc cacagttcgt cgaggcgttc
     9421 ggcgtcgtag gccaggtggg agacgaccag gacggaccgg ccggcgtcgc gcagccgggc
     9481 cgcgagatgc cagaaccgct ggtaggtctc ccagtcgaag ccctggtacg gctcgtccag
     9541 gagcagtagc cgggggtcgc gcatgagcgc gagggtgagg ttcagtttct gtcgggtccc
     9601 accgctgagc agcccggcgc gctggtcggc gtactcggag aacccgagca cctccatgat
     9661 ctcctcggca taccgcaggt cgggcagggc gaaagctgcc tggaagaact ccagatgctg
     9721 gcgcacggtc agcgcgtcgt tgaggacggc gtcctgcggg cagtacccga aacggccctc
     9781 gcgtcggaca ctgccgcgct gcgggcgcag ctcaccggag aggatcttca gaaaggtcga
     9841 cttgcccgtc ccgttctcgc ccacgacgcc gaccagggcg cccgcccgta cggtgagatc
     9901 gactccgcgc aggaccgcgc gtcgcccgta ggcgtggcac agtcccctca ccagcagcgt
     9961 ggtgccgttc tcgaaccgca tcaagtggcc cgtccgttcc tcacgccgag acgaggacgg
    10021 ttcggtccgg gtacagcacc atcgcggtgg ggaaagtacc gtcccagaca tggccgcggc
    10081 cgtggtaccg ctcactttcc atggtccagc gcaggtgacc gcccagaagc tcccaccagg
    10141 cgtgcgcgta ggcgtacagc gcctgcgcac ggtctgtctc cttccatttc cgcacaaggc
    10201 ggtcgacatc gagttcggct cggcggatca gcccgcagac tttgtccacg gcggcctgca
    10261 gggtgagtcc ctcggcgcgc tgcaacacgg gaacggcgtt catgggcacc ggcgcgtcgc
    10321 gttctttccg ataggagaag aggtcgttga ccaacgttcc gtgggccagg caggcagcgt
    10381 gaagggtttc caggtccgag gagtgcatca tctgctccag atcgacgccc gcactgcgct
    10441 ccacacctac cgtgaggaag ctgaagccgg agtccgcgcg ccggaagtcc aggtacgacg
    10501 ccaggtcccg cgtgtgttcc agttgcccct ccctgcccgc atggcacttc acccactcgg
    10561 aaagcccccg gcagtgacgg gtcttctgcc ccggtgtgag atgcgatctg gtctgcgcga
    10621 gcgagtccgc ccacagacgc aggtcgtccg agtcgacagc cgtgtcggac tcatcggcta
    10681 cggccaggta cgcgtcgatc agacgcggcg gagtgtccgg atcctcgagc tcgtcgtcca
    10741 cgatgaatcc ggtcgtggtg aacagggcgg catccaggag atagccgaca tccgccgagg
    10801 gggctgcccg cgtggcgagc ccggccatgt cgtgccgctt gatccggtcc agcaccttgt
    10861 cgcgctgccg tccgatcagc cggtcggcga accatcggtc atgcgcttcg cgcagatgcg
    10921 cgtgctgagg gttgacacgg tcaagaggaa ggatggtccc tccgagcgga agatccagta
    10981 caagaccctc cacaccactc tgttcggcag cggtcacggg cctctccttc acatgcctcg
    11041 tcgatgggtc gtcctgacca acgatcacca tcaggcgaag taatcgggaa agccgcgatg
    11101 ggctgatccg gcggcggtca gggcccggct cgccggcgta ccggagctga gtcgatgccg
    11161 cgtcctgcgc gtatgcgccg cctgcgcgta tgcgccgcct cagagctggc gacgtacctc
    11221 gtcatgcgcg cggccgctgc acggtccgtc ggccgggggt ggccgggtgc tcatgccgta
    11281 cttccgtccg ccagggaggt gacggaggtg aaggtcttgg cgcgggtggt gcagcggccc
    11341 tccgcgtcgg ggggcggggc aggttcggta cagcgggcag tcgaggcagg ccggacggag
    11401 gtctgcaccg ggtgcggtgc cggggagccg cagtcggcgc atgcggctgg ggcgcggaat
    11461 cgggccgtgg tcaatgggca ccgcagcttc cggggcgggt gcccattcgt ggctacgggg
    11521 cccggaactg cgctgcgccg tgtggtcgcg agcgaccgga ggcggcgacg caggcgggca
    11581 gcgggcccga ggcccccggc cgtgtgcccg ccggggcggt gcgtcagagc atggcgagcc
    11641 ggtccaccag cagctccgtc ctccgctcgg tgtcctccgg cggcagccgt ccctcccggg
    11701 tcagggtcgc cagcccgtgc agggccgccc agaacacctc ggtgaacagc cccgggtgga
    11761 cgccgtcccc ggcgacctct ccgaggctct ccagcagggc ggcgaaggcg tccttcagcg
    11821 gctccggggt gtccgcccgc gcgaacgcca ggccgccgtc gagctggaaa atggcgtcgt
    11881 agaccgccgg gttgcgttcg gcgaagtcga ggtaggcgcg ggcgagggcg gtgacccggg
    11941 cgcgcgggcc gtccgcggcg gaggccgcgg cccgcagcgc cgcggccatc tcggcggcgc
    12001 cttcgagggc gacggcgccg atgatctcgc gtttgccgcg gaagtggctg tagaggacgg
    12061 gctggctgta ttcgatgcgc tcggcgagcc gacgtgtggt gaccgcgtcc cagccctgct
    12121 gctctgcgag ttcgcgggcc gtcgccacga tgagccgttc gcggctcgcc cgttcacgct
    12181 ccttgcgttc ctgtaccgac atgatccgat cctagcactg ctagacattg gagcggtggc
    12241 agtactagcg ttgccacatc ggctatcaac gctagattta cgaaggggtc gtcatgctca
    12301 atgcactcga ggtcttcacc accgtggtcg tcggcgtgat ggtcggggtc gagttctccg
    12361 tcgccttcgt cgtcaacccg atcctcgacg gcctcccgga cgactgcggt cagcggggcc
    12421 gcgcccacgg tggccggatg ctcggcgccg tgatgccggt ctggtacatc acctcgctcg
    12481 tcctcgtcgc ggtctgggcc gccgccgggt ggcaccaccc cggcaccggc ctcgtcgtca
    12541 ccgccggcgc actgctgatc ctcagcgtga tcatgtcgat cctgctgctc gtcccgatca
    12601 acaaccgggg caagacgtgg acccccgaca accggcccga cgactggaag cagcagatga
    12661 accgctggga ccgctaccac tacgtccgcg tcgccgtcat catcgccgcc ttcgccctgc
    12721 tggccgccgc cctcacctga gcccgctcgc cggcaccacg ccggtggcgc acgatgccca
    12781 ctccccgagg gcggcagcgg ccaccgagat cccgacatcc gagtaatgcg acccggttgc
    12841 cgcggggacg aatgcgcctt gtccccggcg accgcgtccg ggccgggtgc gaggacggcc
    12901 gacgggcccg cggacgcaca cctggtccag tacggggatg aaccgcgggc cgacagcggt
    12961 ctgcccggcg gtctggacga acgccggtgg gcggcacccg cggtcggcgg cgaggtggac
    13021 ctcgctcgtc cacccgcccc tggagcgtct caggagtgcg actctcggtc ggagttcgcg
    13081 acggcgccgg gtacttcgtc gcgcttcccg cccgggatcg tcttcggtct gctcacgagc
    13141 ggcgtccgga gcaaagtccg gtaggtccgg ctcgttgtcg cgccggagga ccgtgccttc
    13201 acgtcttcgg ccttcacgtc ttcggcgagg gccccgcgac agggcccgcc cgccgcccga
    13261 cgacgaggaa cagtcgccac gcgaacgtgc cggcacgccg gccaactcct tcccgcaacc
    13321 gagcttcccc accccactcc cccacaggac ccaccaactg cacttaatga aagtcaaaag
    13381 aaaagccatg ccaggaacct tgaccgcgac cggcatggcg ggcaaggtgc cggagagcgc
    13441 tctcccaccc attccgcgtc aaggagtctc tccatgccca ctgtcggcat acccccggcg
    13501 gcgccggtgt cgcgcagacc cggtcgccgc gggctcgtcg gcgtcctggt caccgccctg
    13561 gccgccgccc tgctcgccgt cgtccccgcg acgcgggccc aggccgcacc cgcgctgttg
    13621 tcccagggca agccggtcac cgcctccagc caggagcact acggcacccc ggcggccgca
    13681 gccgtcgacg gtgacgacgg cacccgctgg tccagcgccg ccgccgaccc gcagtggatc
    13741 cgcgtcgacc tcggcgcccc cgcctccctc agccgggtcg agctgcgctg ggaggccgcc
    13801 tacgccacgt cctaccgcat cgagacatcc cagaacggct cggcctggtc gacggcctac
    13861 tccaccacca ccggaaccgg gggcacggag accgtgaacg tctccggcac cgcccggtac
    13921 gtccgcatgc tcggcaccgc ccgcgccacc ggatacggct actccctgtg ggagttcaag
    13981 gtgtacggca ccaccggcga cgattccggt ccggtcatcc cgggcggcgg cgacctcggc
    14041 ccgaacgtgc acgtcttcga cccgtccacg cccggcatcc aggccaagct ggaccaggta
    14101 ttcgaggagc aggagtccgc gcagttcggc tccggccggc acgccttcct cttcaagccg
    14161 ggcacctacg acaacctcaa cgcccagatc ggcttctaca cccaggtcct cggtctcggc
    14221 ctgcgccccg acgacacgac gatcaacggt gacatcaccg tcgacgccgg ctggttcaac
    14281 ggcaacgcca cccagaactt ctggcgcggc gcggagaacc tcgccgtgaa gccggtcagc
    14341 agcaccaacc ggtgggcggt ctcgcaggcc gcgtcgttcc gccggatgca cgtcaagggc
    14401 ggcctcaacc tcgcgcccaa cggctacggc tgggccagcg gcggctacat cgccgacagc
    14461 aagatcgacg gccaggtcgg caattactcg cagcagcagt ggtacacccg cgacagctcc
    14521 atcggcggct ggtccaacag cgtgtggaac caggtcttct caggcgtcga gggcgctccc
    14581 gccaccagct tccccgagcc ccgctacacc acgctcgaca cgacgccgat ctcccgcgag
    14641 aagcccttcc tctacctgga cggcaacgag tacaaggtct tcgcgcccgc caagcggacc
    14701 aacgcccgcg gcaccacctg ggcgggcggc acgccgcagg gcgagtcgat cccgctgagc
    14761 gagttctacg tcgtcaagcc cggcgccacc gccgccacca tcaactctgc tctcgcccag
    14821 ggcctgcacc tgctgttcac cccgggcgtc taccacgtcg accagacgat caacgtcaac
    14881 cgggccgaca ccatcgtgct gggcctcggt ctggccacga tcatcccgga cgacggggtg
    14941 acggcgatga gggtcgccga cgtggacggc gtgaagctcg ccggcttcct catcgacgcc
    15001 ggaccggtca actccccgac cctcctggag atcggccacc agggcgcctc gaccgaccac
    15061 gccgcgaacc cgaccaccgt gcaggacgtc tacatccgca tcggcggcgc gggggccggc
    15121 aaggcgacca ccagcatggt ggtcaacagc cacgacacga tcatcgacca cacctgggtg
    15181 tggcgcgccg accacggcga gggcgtcggc tgggagacca accgggccga ctacggcgtc
    15241 cgcgtcaacg gcgacgacgt cctggccacc gggctgttcg tcgagcactt caacaagtac
    15301 gacgtcgagt ggtacggcga acgcggccgg acgatcttct accagaacga gaaggcgtac
    15361 gacgcccccg accaggccgc catccagaac ggtgcgacga agggctacgc cgcctaccgc
    15421 gtcgacgact ccgtggacac ccacgaggcc tggggcctgg gcagctactg caactacaac
    15481 gtcgacccgg acatccgcca ggaccacggc ttcaggacgc ccgtgaaacc gggggtgaag
    15541 ttccacagcc tgctcgtggt ctccctcggt ggcatgggcc actacaacca cgtcatcaac
    15601 gacaccggcg cctccacggt cccggccggc acgacgaccg tgccgtccac cgtcgtgtcc
    15661 ttcccctgac cgatccgtcg gccacgactc ccctccgggc cggatcgcga ccccgcgccc
    15721 ggcccggagg ggccatcagg cggcgccccc ggccgccccg ccccgtcggc tttccccaac
    15781 ccgccaggag cagacgtgtc cacagccctc ccgtatcgca gaccagtccg ccgcgccggt
    15841 gtccccctgc tcgccctcgg cgcgctggtg gcgtcgtcgc tcgccgtcgc cgccccgccc
    15901 gcccaggccg cggaagccct gctctcccag ggcaagcccg ccaccgcgtc gtcccaggaa
    15961 ggcgacggtt acgcggcctc ggcggccgtc gacggcgatc tcaccggcac ccgctgggcc
    16021 agccggtgga gcgaccctca gtggttccag gtcgacctcg ggcagcgcgc cgacctcagc
    16081 cgcgtcgtgt tgacctggga gggcgcgtac gccaagagct accagatcca ggcgtccgac
    16141 aacggcacgc agtggcggac cctgaagacc gtctccggcg gtgacggcgg cacggacgag
    16201 gtcgccgtca ccggcgccgg ccggtacgtc cgcatgctgg gcaccgaacg gtccggcggc
    16261 tacggctact ccctgtggga gttccaggtg tacgggaccg cggagggcac gcctcccgcc
    16321 gacggagggg cggtcaaggt cgcgggcacg caggggaact ggcacctgac cgtcggcggc
    16381 cagccgtaca cggtcaaggg gctgacctgg ggccccgcca tcgcggacgc cccgaagtac
    16441 atgcccgacg tgaagtccat gggcgtcaac acgatccgca cctggggtac cgacggcggc
    16501 accaagccgc tgctcgacag cgccgccgcg aacggcatcc gcgtcgtcaa cggcttctgg
    16561 ctgcagcccg gcggcggccc cggctccggg ggttgcgtcg actacgtcac cgacaccacc
    16621 tacaagaaca acatgctcac cgagttcgcc aagtgggtgg aggcctacga gagccacccg
    16681 gcgaccctca tgtggaacgt cggcaacgag tcggttctcg gcctgcagaa ctgctacagc
    16741 ggctcggaac tggaggcgca gcgcaacgcg tacaccagct tcgtcaacga cgtggccaag
    16801 aagatccaca gcatcgaccc cgaccacccc gtcacctcca ccgacgcctg gaccggcgcg
    16861 tggccctact acaagcgcaa cgcgcccgac ctcgacctgt actcgatgaa ctcctacggc
    16921 gacatctgcg gcgtccggga ggactgggag gagggcggct acaccaagcc gtacatcatc
    16981 accgagggcg ggcccgccgg tgagtgggag gtgcccgacg acgccaacgg cgtccccgac
    17041 gagccgaccg acgtccagaa ggcggagggc tacaccaagg cgtgggactg cgtcaccggc
    17101 caccggggcg tcgccctggg cgccaccctc ttccactacg gcgtcgagca cgacttcggc
    17161 ggcgtctggt tcaacctcgt ccccgacggg ttgaagcggc tgtcctacta ctccgtcaaa
    17221 agggcctaca ccggctcgac cacgggcgac aacaccccgc ccgtcatcac gaacatggcc
    17281 gtcagccccg cttcgtcggc tccggcgggt ggcgagttca ccgtccgtgc cgacgtgcgc
    17341 gaccccgacg gcgacccggt cacgtacaag gtcttcctca gcggcaacta cgccactggc
    17401 gacaagcgcc tggtcgaggc cacatggcgg tccaccggcg acggaacctt cgccgtgacg
    17461 gctccggaga agctcggcgt gtggaaggtg tacatccagg ccgaggacgg ccgcggcaac
    17521 gccggcatcg agaccaagtc ggtcgaggtg gtcgccccac cggtctccgg caccaacgtg
    17581 gcgctgaaca agcccaccac cgcctcctcc ttccagccct cctacggcga ctgcccgtgc
    17641 gagcccgcca aggcgacgga cggcaagaac gacacgcgct gggccagcga ctggagcgac
    17701 ccgcagtgga tccaggtcga cctcggcgcc gccacccccg tccgcaagct ccaactggtg
    17761 tgggaccccg cctacgccaa gtcctacgag gtccaggtct cggacaacgg caccacctgg
    17821 cgcacggtcc acaccacgac cgccggcaac ggtgacgtcg acaccatcga catggcgcag
    17881 accgcgcggc acgtgcgact gcacctgacg gcgcgtggca ccggctgggg ctactcgctg
    17941 cacgagttcg gcatctacgg ctgacccggc agcaacccag gggcccggcc gcccgtccag
    18001 cacgggtgcc gccgggcccg tgctggacgg gcggccgggc acctccgccc gccgtcggcc
    18061 cggcgggctt gacggggagg agatgcccgt cggacggttg gagagcgctc tcccaaccgg
    18121 tggaggggca ggaagcgggg cgggaatgga cgacgaggca ctggatcggc tcatcggcaa
    18181 gctgagcctc gaacagaagg tgcgcctgct caccggcgcg acgacctggc ggaccgccgg
    18241 tgagtccggg atcgggctgc gggagatggt gacctcggac gggcccgccg gggtgcgcgg
    18301 cgaggcatgg gacgagcggc gctcctccgc cctgctgccc tccgcctccg cactgggcgc
    18361 gatgtgggac gaggaactgg tcgaacggct cggcggcctg ctcgcccgtg aggccatccg
    18421 caagggcgtc gacgtggtac tggctcccac gctcaacctc caccgcagcc cgctgggcgg
    18481 ccggcacttc gagtgcttct ccgaggaccc gcggctcacc ggccgtaccg gggccgcgct
    18541 gatccgcggc gtccaggccc tcggggtggc ggccaccgcc aagcactacg tcggcaacga
    18601 ctccgagacc gaccggctga ccgtcgacgt ccgggcgtcc gaacgcaccc tgcgagaggt
    18661 gtacctcctc cccttcgagg cggcggtcga ggccggggtg tgggtggtca tggcggggta
    18721 caacgccgtc ggcggcacca ccatgacggc cagcccgctc ctggcggagc ccctcaaggg
    18781 ggactggggt ttcgacgggg tcgccgtctc cgactgggct gccgtgcgct ccaccgagga
    18841 gcccggccgg gccgccctcg acctcgcgat gccgggcccg gacagtccct ggggcgcgaa
    18901 cctggtacgg gcggtgaagg acggccgggt cgccgaggag gcggtcgacg agaaggtgcg
    18961 gcgactgctc cggctcgccg cccgcgtcgg cgcgctggaa ccgcatcacc cgcgccgggc
    19021 gcccgcgacg gcggcacgtg ccacccgggc gctgctgcgc cgcgccgtca gcgccggttc
    19081 cgtcctgctg cgcaacgacg ccgtcctgcc gctcgactcc gccgagctgt ccaccgtcgc
    19141 ggtcatcggc gtgcacgccg cgtccccgcg cgtccagggc ggcggcagcg cgggcgtctt
    19201 ctgctccgac gtggtcaccc cgctggccgg catccggtcc cgcctgcggg gccgggcccg
    19261 ggtggtgtac gagcccggcc cggcgcctgg agcaccgccc gctcctctcg gcaccgaccg
    19321 gtgctgcgac ccgcgctcgg gcgcccccgg cgtgctcctt cgggtgctcg acgcggcggg
    19381 gcgggagctg cgcgcggagc accggctctc gggccggcag ttggagccgg acctgccccc
    19441 gggcgcccgc acggtggaga tcgccgccgt gctgcgtccc cggcagtcgg gagagtggac
    19501 gttcggcgcc ggagggttcg gacgcatcac gctcaccgtc gacgaccacg tgctcctgga
    19561 cggtgagttc cccggtgaca cggacgaccc cgccgtcgtc cacgtcaacc cgcccgtgca
    19621 cacggtgcgg acggtgctga ccacccagcg gcccgtgcac gtggtggcac ggcgcgaact
    19681 ggtgcccggc cgaggacgcg ccaccgtcgt caccgccgcg ccgcccggac cgtccccggc
    19741 gaccgcgctg gaggaggcgg tgcgggcggc ccgcgacgcc gacgccgcga tcgtggtcgt
    19801 cggcaccacc gagcacagcg agaccgaagg atacgaccgc gccgggctgt cgctcggcgg
    19861 gcaccaggac gagctggtcc gcgcggtgac cgccgcgaat ccgcgcacgg tcgtggtggt
    19921 caacagcggc gggccggtcg agctcccctg gcgcgaggag gcgggcgccg tgctgctcac
    19981 ctggtttccc gggcaggagg ccggcgcggg gctggccgac gtcctgttcg gccacaccga
    20041 gcccggcggc cggctcccca ccacctgggc ggcgaccctg gcggacgcgc ccgtcacccg
    20101 tacccggccg gtcgacggcc ggctcgacta cgccgagggc ctgcacatcg gctaccgggc
    20161 gtggctgcga gccggacgcg agcccgccta ctggttcggc cacggactcg gctacacgac
    20221 gtgggcgtac gcggccgtgg aggctcccgc gcacgtcctg gcggacgagc cgttcaccgt
    20281 tcgggtgacg gttcgcaaca ccggctcccg cgccgggcgc gaggtcgtgc aggtctacct
    20341 ggcccgcccc ggttcagcgg tggagcggcc cgtgcgctgg ttcgccggcc atgcggccgt
    20401 gcgggcggaa gcgggccgga cggcgagcgc cgaggtggtg gtgggcccga gcgcgctgcg
    20461 gcactggtcg gaggcggacc acggctgggc cacggagccg ggcgcctacc ggctcatggt
    20521 gggcaggtcc gcgggggacc ttcggtggga ggggacggtc acggtcagtg gcccctgacg
    20581 gggcccgggc agcgcgctcg ccgggactgc ggctgcgggc cgcgacctgt ggcctgtgcg
    20641 atgccgtgag gatcttccgg ggcgccgccg cgccttcggg tgctgtgcgg gcgcacgccc
    20701 cgggcccgcg gtgggtttcg cgccggggcc gcggcccatg accccggacc ccggtctctg
    20761 ggtgcgcagg tctcctccat ggcagcgggg ggcacgggcc atggccgggg cggccgcctt
    20821 cggtgcaccc cgtcgggaag cggcccgcgc cgctcactgg accgagcgct cccgcagggc
    20881 cgtccgccac gccggatccg gttccaccgg ttcgggttgc tccggccggc cgccacgagc
    20941 gaagaagtcg gcgagcggca ggatcgcggc ccccacggtg acggcgtccg gtcccagggt
    21001 gccgaggtcg atgcgga
//
