LOCUS       NZ_MCOK01000001        30822 bp    DNA     linear   CON 22-OCT-2024
DEFINITION  Nocardiopsis sinuspersici strain UTMC 00102 NOSIN_1, whole genome
            shotgun sequence.
ACCESSION   NZ_MCOK01000001
VERSION     NZ_MCOK01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardiopsis sinuspersici
  ORGANISM  Nocardiopsis sinuspersici
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsidaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 6071583)
  AUTHORS   Tokovenko,B. and Kalinowski,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-AUG-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-JUL-2016
            Assembly Method                   :: SPAdes v. 3.8.1
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 106.0x
            Sequencing Technology :: Illumina NextSeq; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001998325.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 13:01:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,351
            CDSs (total)                      :: 5,274
            Genes (coding)                    :: 5,224
            CDSs (with protein)               :: 5,224
            Genes (RNA)                       :: 77
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 50
            CDSs (without protein)            :: 50
            Pseudo Genes (ambiguous residues) :: 0 of 50
            Pseudo Genes (frameshifted)       :: 13 of 50
            Pseudo Genes (incomplete)         :: 44 of 50
            Pseudo Genes (internal stop)      :: 2 of 50
            Pseudo Genes (multiple problems)  :: 7 of 50
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:06:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4757426
            Orig. end                         :: 4788248
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MCOK01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..30822
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="10"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..30822
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..30822
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:20822](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..20822
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    258..271
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.22"
                     /tool="antismash"
     misc_feature    complement(403..417)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.34"
                     /tool="antismash"
     misc_feature    1822..1837
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.75"
                     /tool="antismash"
     misc_feature    complement(2382..2395)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    3044..3058
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            complement(3697..4356)
                     /locus_tag="NOSIN_RS20565"
                     /old_locus_tag="NOSIN_20325"
     CDS             complement(3697..4356)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012924521.1"
                     /locus_tag="NOSIN_RS20565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20325"
                     /product="response regulator transcription factor"
                     /protein_id="WP_077692324.1"
                     /transl_table=11
                     /translation="MTAPVRVLVCDDQVLIRTGLTTIIDAQPDLEVVGECGDGRAAVDL
                     AGRLRPDVVVMDVRMPVLDGIEATRLLAGAGVPRPVKVLVVTTFNLDEYVYEALRAGAS
                     GFLLKDAPAPRLLHGIRTVATGAALLDPEVTRQLVGRYAARIRPAEGGPKDIPLTPREL
                     EVLRLIADGLSNSEIAAALVISPETVKTFVSRILGKLALRDRVQAVVYAYRHGLVT"
     gene            complement(4353..5507)
                     /locus_tag="NOSIN_RS20570"
                     /old_locus_tag="NOSIN_20330"
     CDS             complement(4353..5507)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017595898.1"
                     /locus_tag="NOSIN_RS20570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20330"
                     /product="sensor histidine kinase"
                     /protein_id="WP_077692325.1"
                     /transl_table=11
                     /translation="MIDRRRFLELWHRLDVTVRDLPLGLLLLALSFVPALHSQGTDLGG
                     VAPRPFDALAVPAIALQCLPLAARRRWPVVCLTLVALGFAVDQLHGYHSLAGIALPIAL
                     LSAGAHLERHRHATALVFSAAYVPLAVTLSRFGSGETPSGFVTFYLVLVLVWGIGAWLR
                     STRAAEAEHRLRVAEDTRAAERTRIARDLHDVVTHHVTAMVVQAEAARYLTAAPDRLDQ
                     ALTAVTDTGRRAITDLRHLLDLLNPDHGTGPGTVPAGGLLTLVEQTRRAGQPVEFTEEG
                     TPAEEAGSADLVAHRVVQEALTNALKHAHGSRTSVRVHHGEREITVEVGTDGSGSRAGS
                     PDGGGWGLAGLRERVDVLGGDFSAGRRTDGGFVVRARIPAGSPS"
     gene            complement(5504..6340)
                     /locus_tag="NOSIN_RS20575"
                     /old_locus_tag="NOSIN_20335"
     CDS             complement(5504..6340)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019608969.1"
                     /locus_tag="NOSIN_RS20575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20335"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_077692326.1"
                     /sec_met_domain="Abi (E-value: 1.3e-14, bitscore: 52.6,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLVWQFLAVAVVALIGGQSLVAVQGNLWLTLAVGVLTAVLSVLV
                     YGWVVRRTERREVTEIAREGAVSAIGLGTLIGVALFGLVIANIAALGFYEVNGLGSVAG
                     AVGLLGFMAAVAVGEEVMWRGVLFRIVEGWTGTWIALVLTGVLFGLVHLVNPHASLWGA
                     IAIAIEAGGMLTAAYVATRKLWLPIGLHFGWNLAGSAIFSTEVSGSDTPQGLLDTALSG
                     PMLITGGDFGPEGSLYSILFCTLATIVLLWMAHRRGRLVPLRRRAEGTGATAKLPG"
     gene            complement(6567..7178)
                     /locus_tag="NOSIN_RS20580"
                     /old_locus_tag="NOSIN_20340"
     CDS             complement(6567..7178)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013156443.1"
                     /locus_tag="NOSIN_RS20580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20340"
                     /product="suppressor of fused domain protein"
                     /protein_id="WP_077693683.1"
                     /transl_table=11
                     /translation="MLEMLPGLVRIYEEWAERYPDVQPLTVQFAADGKRDGGLDGVLAY
                     PLDGHWLLVTFGLTELGEKTSEEPRVSGAGFEFTCRIPREDGDETVPGWILRVLHALAD
                     HFLSGSELDVGHWITTPSPLGGEPANGDMTSLVIVPDVEIRVMDTPNGIVLFHQIVGLT
                     SGEGADVQEAQTAAPLVALLRDRDPKLLTDPGREPVRLDQ"
     gene            7565..7747
                     /locus_tag="NOSIN_RS20585"
                     /old_locus_tag="NOSIN_20345"
     CDS             7565..7747
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017590578.1"
                     /locus_tag="NOSIN_RS20585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20345"
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_077692327.1"
                     /transl_table=11
                     /translation="MPHSTAPDIDLPELDFDSMEVMSVREAVAVPETGATSGSSSCTST
                     SCCGSSSCCSGGSCG"
     misc_feature    complement(7566..7582)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.47"
                     /tool="antismash"
     gene            7899..8081
                     /locus_tag="NOSIN_RS20590"
                     /old_locus_tag="NOSIN_20350"
     CDS             7899..8081
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017544316.1"
                     /locus_tag="NOSIN_RS20590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20350"
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_077692328.1"
                     /transl_table=11
                     /translation="MAMQDSPVIDLPDLDFDSMEVMSVREAVAVPETGATSGSSSCTST
                     SCCGSSSCCSSGSCG"
     gene            8197..9099
                     /locus_tag="NOSIN_RS20595"
                     /old_locus_tag="NOSIN_20355"
     CDS             8197..9099
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017544317.1"
                     /locus_tag="NOSIN_RS20595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20355"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_077692329.1"
                     /transl_table=11
                     /translation="MYAIQATDITKDYGKGEVLHGVSYQVPTGQIAALLGPNGAGKTTL
                     IEILEGHRGRTSGRLSVLGLDPGSRRDFARLRRRMSVVLQQTMLEPGLSVRDILRRHAS
                     YYPDPLDTDEVLDQVDLVEKRSALVKSLSDGMRRRLDLALALTGRPELLFLDEPTTGLD
                     PVSRRRIRGLVSGLRDSGTTVVLTSHDLTEVQELADRVDVIRDGEFIASGSPDDLVRGS
                     SAFTVVEFADPGVAAERLPEGAALVNGRVRIRTDDQDTVVREVQEWATREETEISGLTI
                     VPPSLDDAYIAMLETGRTE"
     gene            9096..9947
                     /locus_tag="NOSIN_RS20600"
                     /old_locus_tag="NOSIN_20360"
     CDS             9096..9947
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017606428.1"
                     /locus_tag="NOSIN_RS20600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20360"
                     /product="ABC transporter permease"
                     /protein_id="WP_077692330.1"
                     /transl_table=11
                     /translation="MSTTETARTRRRPSSFLLHVDGELKEFWRSPITLAFIVLMPVMFY
                     VGFGLAFRSEADVVRVVGDHEITQANLSYGGILGFALMSVAFANVAIGLAIRRHHGLFK
                     RFRTTPVSPATVMGAYLVNTLLTAVIVLVVVTAIGLLGMGVTVDPARVPQLLVALLLGF
                     VCMAPLGAAASLLPPNADAAVPMVNGIFFPAAFLAGGFVILPLGDTVGAVVDLLPGRPL
                     TVLIQGSLAESGPAWDWSAVGLLLAWSLLGTVAALRWFRWASEREPRGFGSAKRKGSGV
                     EG"
     gene            10001..12685
                     /locus_tag="NOSIN_RS20605"
                     /old_locus_tag="NOSIN_20365"
     CDS             10001..12685
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017601292.1"
                     /locus_tag="NOSIN_RS20605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20365"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_077693684.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.8e-23, bitscore:
                     78.9, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYPYLPLRGAAVETDRELVRTLADEEEYRERIRERLLDTLHSSAP
                     GIEDEEHRRTALAAKRDVYNRRPPRTSLAGHPVTRRIDALGAWVRSWERTRAAAGELDA
                     AHGAALAAERAVLAAWARDPLTDRSTAMSSPDLHRAVAARGATDGPPDKRMRKAEPSLV
                     RYHSRSTVKVSPYSLYTGVYFDDMEQPSSVTRDGEPLRFTTDADLRRLLVRQAGRVLAA
                     DPEARLGMEWVLTGGARREGDRLLVRRRRWVPPAPGLRAEAFGEEEVRIPLSGAWGPLV
                     AALERRAARPVRLSELRDGLAADLGHGSDAVMRVLDKLVGTGVLVPWAPAAEQSPDFVR
                     RWYGLARRLPGATAARVAAAFEATRDVLDDFGEATGTERARSVLHLQRLWSAAVSPAAS
                     ADRDDRGSGRASGDRESQEPGEIQESGSRTARRPSDDTASSPLVEDCHVSRGAPVPREW
                     TRAWSADLRGLMPLLFALDDQRVLAGALESVFVDRYGRGGRCTDLDEFAGHARAAFPMT
                     QRLMAGETGEADEDLSRLLAARRRAVEHLNDLSGQDAEAVEVDPAVVEEVASLLPEREF
                     TARRSFAVFGHPDHRGGLVLNHLYGGRARYFSRFLAALPDGVRDRVAAHVRRLGPPDAD
                     TVHMRSALGFNANLSPLLAPEELALRDEPVLADGPSTADLHLVHTPRGLRLVRGSREVD
                     PVYTGFLVPHALPYDEMLVAMLADSPFFSFSDTVIDLHERWERSRSDRRAPGGTPRISF
                     GDVLLFRRRWALDADLLAARPGEDPESLHRRINVERTLRGMPDQVFVRPLQGSRMGPME
                     RAMAPKPQHVDFLSRLHTATAAKRLAHLGPTLFAEELLPCPSEGGLSGPRGRHATEVFL
                     ELSTVPSPVPPMPVPPGEVRLVP"
     gene            12682..13830
                     /locus_tag="NOSIN_RS20610"
                     /old_locus_tag="NOSIN_20370"
     CDS             12682..13830
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017590583.1"
                     /locus_tag="NOSIN_RS20610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20370"
                     /product="lantibiotic dehydratase C-terminal
                     domain-containing protein"
                     /protein_id="WP_077692331.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.5e-12, bitscore:
                     46.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVGLRVTYYDSDKGALLGECLVPAALETSRREGITAAWLHLHWR
                     LGPHCVLYADGDAEAVDAALRDADVRVRGFLEREPSTYAIDPGQYADFSARMGRMELVE
                     PPYAPLEPDNSVRRLEGDPVDTFLRGREAAELKGRVLTDGLSRVAGLVGGRADGGAAAS
                     HVFAGMGAIASQYPEWGLRSGYQAFLSHWKEYFHWSDPDGRAQARLAESYLAQREDLVE
                     TLRAVHEGTTDDPSALSWLEWTRRWLPEAVALARGEHILPFPHPDRLDTATRFGEDTRI
                     RWSGSDERSYSDFHREFRKLDFTRLGDGYGFAAFRFVINCFFDLLPLMGVSPIQRYSIA
                     YLFTEAAQEVVGETWEETVRRVVDHQSSDPELKPTLPWVGDA"
     gene            13823..15577
                     /locus_tag="NOSIN_RS20615"
                     /old_locus_tag="NOSIN_20375"
     CDS             13823..15577
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017590584.1"
                     /locus_tag="NOSIN_RS20615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20375"
                     /product="hypothetical protein"
                     /protein_id="WP_077692332.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 2.6e-06,
                     bitscore: 25.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEHTATPEHTVTRRLKSAVRARSLAEEGVALSMGATAVVVRGAR
                     ADTVWRALEPALRAGFTRRALTERFPAGGRPFLEGVLDQLEEHGFLREAEEEHGLSESE
                     LAAYPHVESLTARPYAALRALAESTVRIRSSCPLLEAEVRRALGRAGFREVHADTGPGT
                     GALLTTRLSVPGREEALHLVDTERGVWVSGPRNTSGGPELVDRVRAWFGGHGALGAPEA
                     SGAAETSEGSGGSGVSGVPGASGNEESPGLAITRSLVAAQLALALVAQVARSVDAAEPP
                     GDPEFMVTTDELVSEPHPFVALPALDPRVEAPLPTGAVPAEEVPERLDAVAHLWDRVFG
                     PVGEPRPDDLEQLPVGLARVERSSLLGAGTTTASARLDALTTALHAVARPEGSGRGTGD
                     GGRARAGDPGFGLGLTPSAAVGEAVGDLVVRVRDRWKDVDRPEPMSASARRLWAALTLR
                     FGVGARLLCQELDGTALCRVTVLGPGEEPMGVSAAPDVDAATREALLRAVARVQAARDG
                     AAGGASGDTASAGSAEETVAVTATRTEAVTASLARWARETGLVRVYAPGGADAWAERGV
                     YTAVASWT"
     aSDomain        13895..14101
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_NOSIN_RS20615_Thiopeptide_F_RRE.1"
                     /evalue="1.40E-08"
                     /identifier="RREFam004.1"
                     /label="NOSIN_RS20615"
                     /locus_tag="NOSIN_RS20615"
                     /protein_end="93"
                     /protein_start="24"
                     /score="25.6"
                     /tool="antismash"
                     /translation="LAEEGVALSMGATAVVVRGARADTVWRALEPALRAGFTRRALTER
                     FPAGGRPFLEGVLDQLEEHGFLRE"
     gene            15772..17526
                     /locus_tag="NOSIN_RS20620"
                     /old_locus_tag="NOSIN_20380"
     CDS             15772..17526
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017606432.1"
                     /locus_tag="NOSIN_RS20620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20380"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_236743407.1"
                     /sec_met_domain="YcaO (E-value: 5.3e-69, bitscore: 231.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 4.9e-78, bitscore:
                     260.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGATLAEPRTLRTGGGLLHVAMSGALAVVGPWTPDASTGCARCAG
                     LWRRDVEGDTAPDRPVPELFPLWADAFAGLAETAAHGPEDLRLALVALDCRTGEVTRHR
                     LVPHPGCSHCFPGGAGLAVPGGLDLRTPRPVAGDALRTRSMDRAGLRARLLDFRFGPAA
                     HVYRDEESPLSLMTCETVAPGHTRREGGYGRSTRFSDSEVPAFLEGVERVTGGHRHTGA
                     ATVFGSYAELADDALDPERLGLHEPEWYGHPVFDLVPYSPDVPTSWVWGWSTLERRRIL
                     VPEHVAYWHAGTEGTRFLYESSNGCAVGGTLEEAVLYGLFEVVERDAFLLAWYSRTRLR
                     EIEADPGLAHLTDLLDERGLHLRLLDLTSDLGIPTALAVVTAPEEAVRSGLAPALSLAT
                     GTHLDPRRAVMAAVEETATNALMYPKWVRMRASVDVERCRPMLEDFTLVRTLEDHTGMH
                     GLWESRRHWEFLGAPTATVPMEGFAAGRPSSFAGADLTALLRERLDAVHALGLDVVVVD
                     QSSAPYTDAAGVRSVKVIVPGALPMTFGHTHRRTRSLERLTRASTLFEGGVPWERHGQV
                     HPVPHPFP"
     gene            17478..19040
                     /locus_tag="NOSIN_RS27500"
     CDS             17478..19040
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017544322.1"
                     /locus_tag="NOSIN_RS27500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_227015223.1"
                     /transl_table=11
                     /translation="MGTTRPGPPGTAPLPVTGPRPPATDSRARVLAGFHGQSHDKDVSP
                     VETLFFGPDLSNGLARPVPGQARPSLPALGPLRDTNASGPPLGGPWSRAQRLLAACVEA
                     VRVRRISAADRYPVHRAYPSPRGLFGADLFVVSGGPVPRCLRVDPQSHALQPLDGLPAP
                     REPEDLADARLVVAVDHRRYPPEYGRLRPSLALLEGGHLLATLGLALERAGLRPRTHFG
                     PTDTPVPSGFSPCGAITLEPDGTSDADGAGEAPEAGSAPETEGTTEAGGTPETEGTTKA
                     GGTPKVSGAPETEGATEPDGFPEADGTPTDTAPTVSAEALSRVAAASAPTGTALRRWLD
                     DRTSGVSTANLVTSSHVGPGGGEGVSTALAAALGAAGEALPVPGALRLYRKVLVADRVD
                     DRAACELVPDGTELPSRPVARTGETNFSSSLGYTLAVDFRPWARAHGDHAQTVLHTLLG
                     WTAQWGCLGAAATGLCARPMRNYQEADWAAVLGLGPDQTPAYQLWVRAERGSYMDLPVD
                     ASP"
     gene            19104..20822
                     /locus_tag="NOSIN_RS20630"
                     /old_locus_tag="NOSIN_20390"
     CDS             19104..20822
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017590587.1"
                     /locus_tag="NOSIN_RS20630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20390"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_077692333.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.2e-66, bitscore:
                     220.9, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF00881 (E-value: 1.1e-12, bitscore: 46.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTWSAVYVHLHREREHLDAFLLDHLAPRAEELVARGRAKAWFF
                     LRYWDGGPHLRVRFLDADADAVDAFSEHMRAAAAETADDAVALDSAAYYANLPQADPGR
                     WHGDGDVVGAVYEPETGRYGGPEALEVCEDFFCVSSAIALAVLRSAPQPHQRQAVAADL
                     ASLAFSVLGFSDVEAVRQARGYHAAWDYSAEVARGDGRAREEAEHLFHSSPSRWLQRRT
                     QLERLVSADGSSTHHLWHRALGETVAKLRRLHAEQPLTNALTRIVWSLLHMHHNRIGLD
                     IDDERRIAWLLSLSYPRWEPAGDFFAPGVASPDRAYAEASKYRTATIGGEHLPRPVPHE
                     EGLSPASAPSHAGLPVVGLPAPGPLTAPVGDVLDQRYSTHGDYGSRMSLADLSSLLGHA
                     AGVSRARSGEPGRRRPPRNHPSPGAAYATQVWVVARHVEGLDRGTYRYRAEEHALVRAD
                     GAAAADRLAELSPFLRGSADGRPGAVADTVGALLVLVGDLGRLREGYGQRALRLLLQEA
                     GHVAQNLSLCATALGLRSLVVSGFADDAVNARLHLDGVDRIALTLLPVGSKPSPA"
     gene            complement(20952..21578)
                     /locus_tag="NOSIN_RS20635"
                     /old_locus_tag="NOSIN_20395"
     CDS             complement(20952..21578)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850553.1"
                     /locus_tag="NOSIN_RS20635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20395"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_227015222.1"
                     /transl_table=11
                     /translation="MAETPIQPALQSRPEPRVANLPVMYPVELSSDRLTLRELRPTDVD
                     DLVKVYGDRKAVEHLSFTPRTKEQCAALIEAAVSDAGRGDRSVYMLAAVQKDHLVGTAR
                     LAVDERPHSAQIGFALRTDLWGQGFGSELVGLLLRLGFDRLGLKRIWGARSPENRASER
                     VMLRAGMVEEGRIRRHLWTRDAWRDSVVHSILDDEWVPTPKTREP"
     gene            complement(21683..21871)
                     /locus_tag="NOSIN_RS20640"
                     /old_locus_tag="NOSIN_20400"
     CDS             complement(21683..21871)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.5"
                     /locus_tag="NOSIN_RS20640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20400"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_077692334.1"
                     /transl_table=11
                     /translation="MSHHRPWHKSSYSGGSGAECVEVAEGDTVFVRDTQNRELGHIEYS
                     PAEWTSFLHDLKAGPLQ"
     gene            complement(21868..22728)
                     /locus_tag="NOSIN_RS20645"
                     /old_locus_tag="NOSIN_20405"
     CDS             complement(21868..22728)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="NOSIN_RS20645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20405"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_077692335.1"
                     /transl_table=11
                     /translation="MPILLDRVISSCEGGLMGLKKISPIWGKYGSDVRKWRKAAKLTLK
                     DLAPLVGLSEASLSYVENGKMSPKDDHAAKIDAALGAKGKLLQSWERCSNHGLVPVGFR
                     KVVDIEKEALELRFYQPVLVPGLVQAPEYAKALFAADRPQADEETIERLVQGRLQRQKI
                     FNRLERPIVCVVVEESVLRRLVGGVPAMRAQLAHLVDVIGKRWVRFQVLPRTPREHPGF
                     PGGFRIMVLEDQTVVSAEHAFDEVLIEDPDQIRKAVSVYGRLQGEALSPHDSLELVRQL
                     EQGEL"
     misc_feature    complement(22672..22674)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    22724..22737
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     misc_feature    22820..22834
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(23001..23014)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.61"
                     /tool="antismash"
     misc_feature    complement(23049..23063)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            23181..23345
                     /locus_tag="NOSIN_RS27855"
     CDS             23181..23345
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NOSIN_RS27855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="ATP-binding protein"
                     /protein_id="WP_227015221.1"
                     /transl_table=11
                     /translation="MVLPGEPDQVAVMRRRIRSRTNGHSPETDAVVLLASELFTNSLRH
                     SHSGGPGER"
     gene            23348..23584
                     /locus_tag="NOSIN_RS27860"
     CDS             23348..23584
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NOSIN_RS27860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="ATP-binding protein"
                     /protein_id="WP_227015220.1"
                     /transl_table=11
                     /translation="MSVFKLPGRYQVRVTDQGPRESEEGISFPYLRASDPLSEGGFGLR
                     LVANEASRWGTIHENGRTTVWFELDRVPLTLSS"
     misc_feature    complement(23766..23779)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.74"
                     /tool="antismash"
     misc_feature    23767..23780
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.17"
                     /tool="antismash"
     gene            23812..24447
                     /locus_tag="NOSIN_RS20655"
                     /old_locus_tag="NOSIN_20415"
     CDS             23812..24447
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013540.5"
                     /locus_tag="NOSIN_RS20655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20415"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_077692336.1"
                     /transl_table=11
                     /translation="MVLLCGHCGNPREGGAPTYRCTCIPAHVWEEPDLAQAVRTLNLSE
                     VIRCMRQHPDTRHLSQVALATMSGLSQAMVSRLENGVNVASINRAVDALAGLGAPGAAD
                     GKRWRLPDDSEPLPPAKPQMTPGVPCVVITSPVPIYVQVMDPPDPSTTGTNRHSDVAFV
                     IDTDGPRLIVNQDIPWGVTSAPGGATAWFALTDREQHITTAHELKART"
     misc_feature    24544..24559
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.88"
                     /tool="antismash"
     gene            24600..24953
                     /gene="tgmA"
                     /locus_tag="NOSIN_RS20660"
                     /old_locus_tag="NOSIN_20420"
     CDS             24600..24953
                     /codon_start=1
                     /gene="tgmA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017563372.1"
                     /locus_tag="NOSIN_RS20660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20420"
                     /product="putative ATP-grasp-modified RiPP"
                     /protein_id="WP_077692337.1"
                     /transl_table=11
                     /translation="MSPKNLSTLLESPDGESRAEIARLGDAFPLDPSTAIFEASDEAPT
                     QVRPWGLRRAVTPKLRPEVAEAVDRFVYDPVTQQGTDRITGAPAVGKRSSGTKETTGDP
                     DGSRPTAEETTSD"
     gene            24953..25933
                     /gene="tgmB"
                     /locus_tag="NOSIN_RS20665"
                     /old_locus_tag="NOSIN_20425"
     CDS             24953..25933
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tgmB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017563371.1"
                     /locus_tag="NOSIN_RS20665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20425"
                     /product="ATP-grasp ribosomal peptide maturase"
                     /protein_id="WP_077692338.1"
                     /transl_table=11
                     /translation="MVSSAARKAVLVLTNTEDGTADPVIHHLSERGVPVVRMDPGDFPA
                     SMTVEAAFDGEHWEGAVHDAFRGVDLGSVRSVYYRRPSQFTLAEGMSGPDQRWAYREAR
                     MGFGGVLLALDCLWINQPSRMSAAEYKPVQLATAARAGLRVPRTIITNVPGHAADWAAG
                     ISGPVVYKPIGGALHVEQGRTWIVYANAVAAVEELRDPAVGLTAHCFQEWVDKAFEVRL
                     TIVGKAMSAVAIHARSQAAHIDWRSDYGAHRYEVVDVPDAVRFGLERYMHAFGLVYGAA
                     DFVVSPDGRWTLLEVNPNGEWGWLADHCGLPVGQSIAALLEKGQM"
     gene            25930..27111
                     /gene="tgmC"
                     /locus_tag="NOSIN_RS20670"
                     /old_locus_tag="NOSIN_20430"
     CDS             25930..27111
                     /codon_start=1
                     /gene="tgmC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013156437.1"
                     /locus_tag="NOSIN_RS20670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20430"
                     /product="ATP-grasp peptide maturase system
                     methyltransferase"
                     /protein_id="WP_077692339.1"
                     /sec_met_domain="PCMT (E-value: 6.4e-26, bitscore: 89.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRAVHELSSGLTAHMIEEGVLVPGDRLTEAFRRVDRGVFVPAFA
                     LHEHTSQGVRYRLVRGEVPEQHEAWARHVYADETLIIEIAGEPVIDALPGGTGTGRWTS
                     SSTMPSLMVRMLHQLDLDGDPRVLEVGVGSGYNAAILCEVLGSDRVTSIDISPRLAFDA
                     TQRLSALGYTPVVAEYDGHKGFPDRAPYDRIISTTAFTHVPPEWIRQTAPEGDILVNIA
                     GGTGGAMLKLQVRDDHTAQGRFIPQWAGFMPARSETPRQRVTVDDAGEQSTTALNPAVV
                     REEPAMAFLAQLATTDADTVLRTADDGADFLFMEGADGAWAEIDTDTVNGRHPVVQGGP
                     RRLWNQVENAHHWWLANGQPDWSAFGATVIPEEQHVWFGSPESDQRWPLPHPR"
     misc_feature    27337..27348
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.55"
                     /tool="antismash"
     gene            27369..27893
                     /locus_tag="NOSIN_RS20675"
                     /old_locus_tag="NOSIN_20435"
     CDS             27369..27893
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017602386.1"
                     /locus_tag="NOSIN_RS20675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20435"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_077692340.1"
                     /transl_table=11
                     /translation="MFTMRLATEADTPAVTSMITARCGWMEQQGLESWRENIDDLAGQS
                     GSGFMWVLEFEGSIVGCTTVMTQAPPKDWTPEEADEPALYLFTTVTDPAYQEHKPGTLI
                     ALWAVDRAARQGRTWVRRGCFFPELVKYYETQGYSLVKEQNRSAGHLYLLARRAERLDL
                     EALGMETRTTA"
     gene            27928..28242
                     /locus_tag="NOSIN_RS28125"
     CDS             27928..28242
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.5"
                     /locus_tag="NOSIN_RS28125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_077692341.1"
                     /transl_table=11
                     /translation="MGGTKAFVWGRSTHPDSAGDTNCVEVAGGAPTAVRDTQNREQGHP
                     AFAAAEWAVPVDTLRDHDWPPGPKAVLPHGRPPSFVSSHGDGRLEQMSSILTLRTVWKE
                     "
     misc_feature    complement(28357..28371)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.41"
                     /tool="antismash"
     misc_feature    28358..28372
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 21.93"
                     /tool="antismash"
     gene            28463..29062
                     /locus_tag="NOSIN_RS27870"
                     /old_locus_tag="NOSIN_20440"
     CDS             28463..29062
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017600446.1"
                     /locus_tag="NOSIN_RS27870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20440"
                     /product="hypothetical protein"
                     /protein_id="WP_227015219.1"
                     /transl_table=11
                     /translation="MRKFSAAALIRAIGTAKALFASPCGRHSSVCGRRRRSTRVRRYVP
                     VPAPVEDTAPPAPPMRTDRAPERPRLPAPVPAPRLAPPSERFPADEIALVRPYYEARER
                     ELARVRATATTRPHRWTGEDVPPRGDLLAAGPFPAPSPEPLPVPAPRAPSPACEDPEDW
                     RTLTRLTRVWLDQQRRRTQQPTQRSGQRHHRQAVPA"
     gene            29059..>29544
                     /locus_tag="NOSIN_RS20690"
                     /old_locus_tag="NOSIN_20445"
                     /pseudo=""
     CDS             29059..>29544
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019609229.1"
                     /locus_tag="NOSIN_RS20690"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="NOSIN_20445"
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTFLSMPKVPRPLVFWEHRVYPGTLDQLARVRAELATDLAGFDED
                     LVETVRLCASELFANSVKYTDSGGRDGEVLRALSMPDARTLRFSVSDCGGGGGVPAVPE
                     ERTEDEWSWAEGRRGLLLVENLSRRWGHFRLAPWADLGTHVWAVFDVEAGAAPPDPRP"
     misc_feature    complement(29627..29641)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.66"
                     /tool="antismash"
     misc_feature    29628..29642
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.62"
                     /tool="antismash"
     misc_feature    complement(29703..29722)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.74"
                     /tool="antismash"
     misc_feature    complement(29741..29758)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.64"
                     /tool="antismash"
     misc_feature    29763..29780
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.44"
                     /tool="antismash"
ORIGIN
        1 gcgaccggtt ccactggctg ggcgaggagg agatgggcga cctggcggcg cccctgtcgg
       61 aggcgcgggc caccgccacc cgggtcctgg aggagttcga gaccgtccag accctgaccc
      121 ggcaggccgc cgacaccctc gcggagaccg agaagagggt ggtcgcgctc atccggacgg
      181 cccgcgggga gacgccgcgg tcggcggagg gctgggtgcg gcggctgacc gagctgcgcc
      241 gcgcccaggg gcaggcggcc acgctgcgcg agacgcgcta cgtggacacc gagcgcctgg
      301 acgacctgga cggcaggctc tcggaggaga tcgccgcgac cggccgccgc actgtggcct
      361 tcctggaacg aggcgaggcc ttcagcgggt accacgacga ggtggaccgg ctcgtcgcgg
      421 acgccgaggg catcgaggcg gtcagcgccg cgacggccgt cggcgagcgc gtcgccgagc
      481 agaccgaggg cctgcaggtg gtcaccgagg tcgtcgggtc cctggacatc ggcgacgccc
      541 aggtccgcac gcgcatcctg gagcgggtca gcgaggtgct ggccgggatc aaccgggcgc
      601 gcgccacgct ggaggcgcgg cgcggggagc tgctggccct ggagggccgg gcggagttcg
      661 cggccgagtt cgcgctgctg ggacaggcgg tcacgggcgc cctggccgcc gccgacaccc
      721 cggaccggtg cgacgagcag ctcggacgcg tcatgctcca actggagaac ctggagtcgc
      781 ggttcgccga gttcgacgac ttcctcgggg agttggcgga caagcgcgag gacgtgtacg
      841 aggcgttctc cacgcgcaag cagtcgctgg tggacgagcg ggcgcggcgg accgaccgcc
      901 tggcatcgtc ggccgcccgc gttctggagg gcgtgcaccg gcgggtcgcg aaactggaca
      961 cgctggagga cgtcaacacc tacttcgcgt cggacgcgat ggtggcgcgg ctgcgccgca
     1021 ccgcggagga gatgcgcgaa ctcggcgaca ccgtgcgcgc ggaggagctg gacggccagg
     1081 tcatggccgc ccggcaggag gcggggcggg ccctgcggga ccgcgccgac ctgttcgagg
     1141 gcggcgcggg cggcgagacg atccgcctgg gcaggtaccg gttcgcggtg aacacccagc
     1201 cgatcgacct gacgctcacc ccgcacggcg gagagatgtc ggtggcgatc accggcaccg
     1261 acttccgggc tccggtcacc gacgaggggt tcgggcggac ccggcacctg tgggaccgga
     1321 tgctggtgtc ggagagcccg gaggtgtacc gcgccgagta cctggccgcg tcgatcctgg
     1381 ccgcggccga ggagggcgcg gacgggctgt cgctggagcg gcttcgcgag gccgaggtgc
     1441 acgccgagaa cggctcgtcg ctgacggcgc tcgtgcgcga cgtcgccgcg gcccggtacg
     1501 acgaggggta cgagcggggc gtgcacgacc acgacgccgc gcggatcctg tcggcgctgc
     1561 tgcggctgcg caccggcgcc ggactgctgc ggtacccggg cgcggcgcgt gcggcggcgc
     1621 agttgttctg ggcgttcggc gccaccgggg agcagcggtc ggcgtggcgg acccgggcgg
     1681 cctcgctggc ccgggcccgc gaggtgttcg gggtgcgccg gtccgcggcg gtcgacgggc
     1741 tgcgcgcgga gctggcggcc ggtgtggacg gcttcctgac cgggacgggg ctgcaccagg
     1801 acgccgacct ggacctggtg ggcgagtacc tgttcgagga gatcgcctcg gagactcccg
     1861 gtgagcgggg tttcgtgtcc ggcgcgggcg cccgtctgct gctggaccgc ttccaccggg
     1921 ccctgggcag cgcgcgggag accacgcgca aggccttcga ggaggacctg cgcgagctcg
     1981 acggcgacct ggcggcgcgg caccagttgg tgacggcgtg gctggaggcg ttcgccgcca
     2041 cccaggagga tgtggaccca ggcgacctgc ccgaggccgc cgcgatcgag ctggccgccg
     2101 tggaccggta cgagtcgtcg gcggccgtgc acgagagcgt gggcgggctg ctgggctcgc
     2161 acccgcgcgt gcgcgagcgc tccctggagg tgcgcctgga cgagttcctg ccgcgcaccc
     2221 gccggttccg gctggaggag gtgcccgcct accgggactt ccagcggcgc cgcaacgagc
     2281 tggtggcggc cgagcgcgag cgcctgcggc tggaggagta ccggccgaag gtgatgagcg
     2341 ggttcgtccg caacaagctg ctggacgagt cctacctgcc cctgatcggc gacaacctgg
     2401 ccaagcagtt gggggcggcc ggggacgaca agcgcaccga ccagagcggc ctgctgctgc
     2461 tcatctcccc gcccgggtac ggcaagacca cgctcatgga gtacgtggcc agccgcctgg
     2521 gactggtgtt cgtgaaggtc aacgggcccg cgctggggca cgcggtgacc tcgctggacc
     2581 cggacgaggc tccggacgcc acctcccgcc aggaggtcga gaagatctcc ttcgcgctgg
     2641 aggcgggcag caacacgatg ctgtacctgg acgacatcca gcacacgaac cccgagctac
     2701 tgcagaagtt catctcgctg tgcgacggcc agcgccgcat ggagggcgtg tggaacgggc
     2761 ggacccggac ctacgacctg cggggcaagc ggttcgcggt gtgcatggcc ggcaacccct
     2821 acaccgaaca gggcaagcgg ttccggatcc cggacatgct ggccaaccgc gccgacgtgt
     2881 acaacctggg cgacgtgctg tcgggcaggg aggagctgtt cgcgctgagc tacgtcgaga
     2941 acgcgctcac ctcgaacccg gtcctggcgc cgctgtccac ccgggaccgg gaggacgtgt
     3001 accggttcgt gcggatggcg cggggcgacg actcggtggg cgcggaccag ctcggccacc
     3061 cgtactcggc ggccgaggtg gaccggatcg tgtcggtgat gcgcaagctg ctgcgggtgc
     3121 aggaggtggt gctggccaac aaccaggcct acatcgcctc ggccgcgcag tcggaggacg
     3181 cgcgcaccga gccgccgttc cggctccagg gctcgtaccg gaacatgaac cggctggcgg
     3241 agaggatcgt gccggtcatg aacggcgccg aggtggaggc cgcgatcgac gaccactaca
     3301 tgggcgaggc gcagaccctg acgtcgggcg cggaggcgaa cctgctcaag ctcgctgagc
     3361 tgcgcggggt gatgacgccc gagcaggagg cccgctggac ggaggtcaag gaggccttcc
     3421 gccggggccg ggccctgggc ggtgccgacg acgacccgat gaccagggcc atcggcgcgg
     3481 tgggcctgct cgccgaccgg gtgggcgaga tcggcgccgc gatcggccgg ggctccgagc
     3541 ggtagccggg cggaccggcc gagggacgca cgggccgccg ccccgggaac cacccggagg
     3601 cggcggcccg cccgtgtgtc cggtgggcgg agggtcttcc ggcggcgcgc gctcccggcc
     3661 atggccccgg cgctccgccg ccgcccgaac ggcgcgtcag gtcaccaggc cgtggcggta
     3721 ggcgtagacg accgcctgga cgcggtcgcg gagcgcgagt ttgccgagga tgcgcgacac
     3781 gaaggtcttg acggtctccg ggctgatcac gagggccgcg gcgatctcgc tgttggagag
     3841 gccgtccgcg atgaggcgga ggacctccag ttcgcggggg gtcagcggga tgtccttcgg
     3901 gccgccctcc gcgggccgga tccgggcggc gtacctcccc acgagctggc gggtcacctc
     3961 ggggtccagc agtgccgcgc ccgtggccac ggtacggatc ccgtgcagca gccggggagc
     4021 cggagcgtcc ttgagcagga acccgctcgc cccggcgcgc agggcctcgt agacgtactc
     4081 gtccaggttg aacgtcgtca ccacgagcac cttgacggga cgcggcaccc cggcaccggc
     4141 cagcaggcgg gtggcctcga tgccgtcgag caccggcatg cgcacgtcca tcaccacgac
     4201 gtccgggcgc agacggccgg cgaggtcgac ggcggcccgc ccgtccccgc actcgcccac
     4261 cacctccagg tcgggctggg cgtcgatgat cgtcgtcagc cccgtgcgga tcagcacctg
     4321 gtcgtcgcag accaggaccc ggaccggcgc ggtcacgacg ggctccccgc gggtatgcgc
     4381 gcccgcacga cgaagccgcc gtccgtccgc cgaccagcgc tgaagtcgcc gcccaggacg
     4441 tcgacccgtt cgcggaggcc ggcgaggccc cacccgcctc cgtcggggga cccggcccgc
     4501 gagccggagc cgtccgtgcc gacctccacc gtgatctccc tttcgccgtg gtgcacccgg
     4561 accgaggtgc gactgccgtg ggcgtgcttg agggcgttcg tcagcgcctc ctgcacgacc
     4621 cggtgggcca cgaggtcggc gctgccggcc tcctccgcgg gtgtgccctc ctcggtgaac
     4681 tccacaggct gcccggcacg gcgcgtctgc tccacgagcg tgaggagtcc gccggcgggc
     4741 accgttcccg gcccggtgcc gtggtcgggg ttgagcaggt cgagcaggtg ccgcaggtcg
     4801 gtgatggccc ttcgcccggt gtcggtgacg gcggtcaggg cctggtcgag gcggtcgggt
     4861 gcggctgtca ggtagcgcgc cgcctcggcc tgcacgacca tcgccgtcac atggtgggtc
     4921 accacgtcgt ggaggtcgcg ggcgatgcgg gtgcgttcgg cggcgcgggt gtcctccgcg
     4981 acacggaggc ggtgctcggc ctccgcggcc cgggtggagc gcagccacgc cccgatgccc
     5041 cacacgagga ccagcaccag gtagaacgtc acgaacccgc tcggtgtctc gcccgaaccg
     5101 aaccgggaga gcgtgaccgc cagcggcacg tacgccgcgg agaacacgag cgcggtggcg
     5161 tgccggtgcc gttccagatg ggcgcccgcg ctcaacagcg cgatgggcag cgcgatgccc
     5221 gcgagcgagt ggtagccgtg gagctggtcg acggcgaagc cgagcgccac cagggtgagg
     5281 cagacgaccg gccaccgtcg gcgcgcggcg agcgggaggc actggagggc gatcgccggg
     5341 acggccagtg cgtcgaaggg gcggggcgcc acgccgccga ggtccgtccc ctggctgtgc
     5401 agcgccggca cgaaggagag cgccaggagc agcagcccga gtggaaggtc ccggaccgtg
     5461 acgtcgagcc ggtgccacag ctccaggaac cgccgacgat cgatcatccg ggaagcttag
     5521 cggtggcgcc ggtcccctcc gcacgccggc gtaggggcac cagacggccg cgccggtggg
     5581 ccatccacag gagcacgatc gtcgccagcg tgcagaacag gatcgagtac aggcttccct
     5641 ccggcccgaa gtcgccgccg gtgatcagca tcgggcccga caacgcggtg tccagcagtc
     5701 cctggggagt gtcgctgccc gagacctcgg tgctgaagat ggcggaccct gcgaggttcc
     5761 agccgaagtg caggccgatc ggcagccaca gtttgcgggt ggcgacgtag gcggcggtga
     5821 gcatgccgcc ggcctcgatc gcgatggcga tggcgcccca caggctggcg tgcgggttga
     5881 ccaggtgcac caggccgaac agcacaccgg tcagcaccag cgcgatccac gtcccggtcc
     5941 acccctcgac gatccggaac aggacgccgc gccacatgac ttcctcaccc accgcgaccg
     6001 cggccatgaa gccgagcagc cccaccgcgc ccgccaccga gcccaggccg ttgacctcgt
     6061 agaacccgag ggcggcgatg ttcgcgatga cgagcccgaa cagcgcgacg ccgatcagcg
     6121 tccccaggcc gatcgcggac acggcgcctt cccgggcgat ctccgtgacc tcgcggcgct
     6181 cggtccggcg taccacccac ccgtagacga gcaccgagag cacggccgtc agaacaccga
     6241 cggcgagtgt gagccacagg tttccctgca ccgcgacgag gctctggcct cctatgagag
     6301 cgaccaccgc aacggccaag aactgccaca ccagtctcac gagaactcct ttgccggatc
     6361 cgcggccgaa gcgccgcgac tgcgtcgaac actacggatc cggcggttcg gagtcgtcac
     6421 cccgcggtgg acacctgcgc gtagctcgca cgggggacag ggggccgggc cggagcgaag
     6481 cgacgtgcgc gcccgggcac cggcggggag gcacgcgtcc cgggaccgaa cgcgggacgc
     6541 gggtccacgg ggctcgggat ccgctgctac tggtccaggc ggacgggctc cctgcccggg
     6601 tcggtgagca gcttcgggtc acggtccctc aggagcgcga cgagcggggc ggcggtctgc
     6661 gcctcctgga cgtcggcgcc ctccccggac gtcaggccga cgatctggtg gaagaggacg
     6721 atcccgttgg gggtgtccat gacgcggatc tcgacgtcgg gaacgatgac cagggaggtc
     6781 atgtcgccgt tggcgggctc gccgccgagc ggggacgggg tggtgatcca gtggccgacg
     6841 tccagttcgc tgccggagag gaagtggtcg gccagggcgt ggaggacgcg caggatccag
     6901 ccggggacgg tctcgtcccc gtcctcgcgc gggatccggc aggtgaactc gaagcccgcg
     6961 ccggagaccc ggggttcctc gctggtcttc tcgccgagct cggtcagccc gaaggtcacc
     7021 agcagccagt ggccgtcgag gggataggcg agcaccccgt cgaggccccc gtcccgcttc
     7081 ccgtccgccg cgaactggac cgtcagcggc tgcacgtcgg gataccgctc cgcccactcc
     7141 tcgtagatcc ggacgagtcc gggcagcatc tccagcatcg cgtcgtcgct ctccaggccg
     7201 atggccttcg tcggtggtcg ttcgccttcc gaggatatga gcgcgccggg ggcgtccggc
     7261 ccggtggcgg cccggccggg gaccgagggt cccggggaaa gggccgggta tccggcgagt
     7321 gagggcacgg agggtattcg aataaccact cgaattctcc acttcacccg gggataaacc
     7381 cgggttctca ttccggccgg tacgggggcc cgaaaaccgg cgaaggcttc cctgttacgg
     7441 ggggtgtaac tgacgaccac acttcaggaa atgatcaata catcctctat ctacctcgtt
     7501 cgccgcatgc tattttcttt tggcccgggg ggtcaggcag aaacgaacta gcgaagaggc
     7561 acctatgccc cattcgacag cacccgacat cgacctgccg gagctggact tcgacagcat
     7621 ggaggtcatg agcgtccgcg aggccgtcgc ggtccctgaa acgggtgcca cgagcggctc
     7681 cagcagctgc acctccacct cgtgctgcgg ctccagcagc tgctgctcgg gcggctcctg
     7741 cggctgagcc gattcggcta cattcccgat accaacgtcc cccaaacccc cgattcgata
     7801 attcacgcca tatcagcaga tcaaagcgtg aaccaattcg acgtgcctgc tcgaaggcac
     7861 gcacatcccc tgaacccagc ctcagaagaa ggtgcttgat ggcaatgcag gactcccccg
     7921 tgatcgacct gcccgacctc gacttcgaca gcatggaggt catgagcgtc cgcgaggccg
     7981 tcgcggtccc cgaaacgggc gccaccagcg gctccagcag ctgcacctcc acctcgtgct
     8041 gcggctccag cagctgctgc tcctcggggt cgtgcggcta gcggtgctcc ctcggggctc
     8101 ccgccccgga tccagcggca ccgcccaggg cggccccctc tccggtccgg gggccgcccc
     8161 ctcacgcccc accccgacga accacgaggg ccgcacgtgt acgccatcca agccaccgac
     8221 atcaccaagg actacgggaa gggggaggtc ctccacggcg tctcctacca ggtgcccacc
     8281 gggcagatcg ccgcgctgct cggccccaac ggggcgggca agacgacgct gatcgagatc
     8341 ctggagggac accggggacg cacctcgggc cggctgtccg tgctggggct cgacccgggc
     8401 agccgccgcg acttcgcccg gctccgcagg cgcatgagcg tcgtcctcca gcagaccatg
     8461 ctggaacccg gcctgtcggt gcgcgacatc ctgcgccgcc acgcctccta ctaccccgat
     8521 ccgctcgaca ccgacgaggt cctcgaccag gtcgacctcg tggagaagcg ctccgccctg
     8581 gtcaagtccc tctccgacgg catgcgccgc cgcctggacc tggccctggc cctcaccggg
     8641 cgccccgagc tgctcttcct ggacgagccc accaccggcc tggacccggt gtcgcgccgc
     8701 cgcatccgcg gcctcgtctc cgggctgcgc gacagcggca ccaccgtggt cctgacctcg
     8761 cacgacctca ccgaggtcca ggagctcgcc gaccgggtgg acgtcatccg cgacggcgag
     8821 ttcatcgcgt cgggcagccc cgacgacctg gtccgcggtt cctcggcctt cacggtggtg
     8881 gagttcgccg accccggcgt cgccgccgaa cgcctgccgg agggcgccgc gctcgtcaac
     8941 gggcgggtgc gcatccggac cgacgaccag gacaccgtcg tgcgcgaggt ccaggagtgg
     9001 gccacgcggg aggagaccga gatcagcggg ttgacgatcg ttccgcccag cctcgacgac
     9061 gcctacatcg cgatgctgga gacgggaagg accgaatgag caccaccgag accgcgcgca
     9121 ccaggcgccg acccagcagc ttcctcctgc acgtggacgg ggagctgaag gagttctggc
     9181 gctcccccat caccctggcg ttcatcgtcc tgatgccggt gatgttctac gtcggcttcg
     9241 ggctcgcgtt ccgctccgag gccgacgtgg tccgtgtggt cggggaccac gagatcaccc
     9301 aggccaacct gagctacggc ggcatcctcg gcttcgcgct gatgtcggtg gccttcgcca
     9361 acgtggccat cggcctggcc atccgccgcc accacggcct gttcaagcgc ttccgcacca
     9421 ccccggtcag cccggcgacg gtgatgggcg cctacctggt gaacaccctg ctcacggcgg
     9481 tgatcgtact ggtggtcgtc accgcgatcg gcctgctcgg catgggcgtg accgtcgacc
     9541 cggcgcgtgt accgcaactg ctcgtcgcgc tgctgctcgg cttcgtgtgc atggccccgc
     9601 tgggcgcggc cgcgtcgctg ctgccgccca acgccgacgc cgccgtgccg atggtcaacg
     9661 gcatcttctt ccccgcggcc ttcctggcgg gcgggttcgt catcctgccg ctgggcgaca
     9721 ccgtcggagc ggtcgtggac ctgctgcccg gccgccctct gaccgtcctc atccagggtt
     9781 ccctggccga gtccggcccc gcctgggact ggtcggcggt ggggctgctg ctcgcctggt
     9841 ccctgctggg cacggtggcg gcgctgcgct ggttccggtg ggcctccgag cgcgaaccgc
     9901 gcgggttcgg atcggccaag cgcaaggggt cgggggtcga gggttgatcc tttctccgtt
     9961 cgactgcgtg gagggcccct acctggtctc ccgcgtgaac atgtacccct acctgcccct
    10021 gcgcggcgcg gccgtggaaa cggaccgcga gctggtgcgc accctcgccg acgaggagga
    10081 gtaccgggag cggatccgcg agcggctgct cgacaccctg cactcgtccg cccccggcat
    10141 cgaggacgag gagcaccgga ggacggcgct ggccgccaag cgcgacgtgt acaaccggcg
    10201 cccgccccgg acgtcgctgg ccggccatcc ggtcacgcgg cggatcgacg cgctcggcgc
    10261 gtgggtgcgg agctgggagc gcacacgcgc cgccgccggg gaactcgacg ccgcgcacgg
    10321 agccgccctg gccgccgagc gcgccgtgct cgcggcgtgg gcgcgcgacc cgctcaccga
    10381 ccgcagcacg gcgatgtcca gcccggacct gcaccgggcg gtggcagcgc gcggggccac
    10441 cgacggaccg cccgacaagc ggatgcgcaa ggccgagccg tccctggtgc gctaccactc
    10501 gcgctccacg gtgaaggtca gcccgtactc gctctacacg ggcgtgtact tcgacgacat
    10561 ggaacagccg tcgtcggtca cgcgcgacgg cgagccgctg aggttcacca ccgacgccga
    10621 cctgcgccgc ctgctggtcc ggcaggcggg acgcgtgctg gccgccgacc cggaggcccg
    10681 cctggggatg gagtgggtgc tcaccggcgg ggcccgccgc gagggcgacc gcctgctggt
    10741 gcgccgccgc cggtgggtgc cgcccgcacc cgggctgcgc gcggaggcgt tcggcgagga
    10801 ggaggtgcgc atcccgctct cgggggcgtg gggccccctg gtggccgcgc tcgaacggcg
    10861 cgcggcgcgg ccggtgcggt tgtccgagct gcgcgacggc ctcgcggcgg atctggggca
    10921 cgggtccgac gcggtgatgc gcgtgctgga caagctggtc ggaacgggtg tgctggtgcc
    10981 gtgggcgccg gccgccgagc agtcccccga cttcgtccgg cgctggtacg ggctggcccg
    11041 gcggcttccg ggggcgaccg ccgcacgggt ggcggcggcc ttcgaggcca cccgggacgt
    11101 gctcgatgac ttcggggagg ccacgggcac ggaacgggcg cgttccgtgc tgcacctgca
    11161 acgcctgtgg tcggcggcgg tgagcccggc ggcctccgcg gaccgggacg accgcgggag
    11221 cggaagggcc tccggggacc gggagtccca ggagcccggg gagatccagg agtccgggtc
    11281 ccggacggca cggcggcctt ccgatgacac ggcctcctca cccctggtgg aggactgcca
    11341 cgtctcacgc ggcgcaccgg tcccacgcga gtggacccgc gcgtggtccg ccgacctgcg
    11401 cggactcatg ccgctgctgt tcgccctgga cgaccagcgg gtgctggcgg gcgcgctgga
    11461 gagcgtgttc gtggaccgct acggccgggg cggccggtgc accgacctgg acgagttcgc
    11521 cgggcacgca cgcgcggcct tccccatgac ccagcgcctg atggcgggtg agaccggcga
    11581 agcggacgag gacctgtccc ggctgctggc cgcccggcgg cgtgcggtcg agcacctcaa
    11641 tgacctgtcg gggcaggacg ccgaggcggt cgaggtggac ccggccgtgg tggaggaggt
    11701 cgcctcgctc ctgcccgagc gggagttcac cgcacggcgc tccttcgccg tgttcgggca
    11761 ccccgaccac cggggcgggc tcgtcctcaa ccacctgtac ggcggacggg cgcgctactt
    11821 cagccggttc ctggccgcgc tgccggacgg cgtgcgcgac cgggtcgcgg cacacgtgcg
    11881 ccgcctgggt ccgccggacg cggacaccgt tcacatgcgg tccgcgctgg ggttcaacgc
    11941 caacctgtcg ccgctgctcg cccccgagga gttggcgctg cgcgacgagc cggtcctggc
    12001 ggacgggccc tccaccgccg acctccacct cgtgcacacc ccgcgcgggc tgaggctggt
    12061 gcgcggctcc cgtgaggtcg acccggtcta caccggcttc ctggtgccgc acgcgctgcc
    12121 ctacgacgag atgctcgtgg cgatgctcgc cgactcgccg ttcttctcgt tcagcgacac
    12181 cgtcatcgac ctgcacgaac gctgggagag gagccgctcc gaccgccggg cgccgggcgg
    12241 caccccgcgg atctccttcg gcgacgtgct gctgttccgc cgacgctggg ccctggacgc
    12301 cgacctgctg gccgcccgtc ccggggagga cccggagtcg ctgcaccggc ggatcaacgt
    12361 cgagcggacc ctgcggggca tgcccgacca ggtgttcgtc cgaccgctcc agggctcgcg
    12421 gatgggtccg atggagcggg cgatggcgcc caaaccccag cacgtggact tcctgagcag
    12481 actgcacacg gcgaccgccg cgaaacggct ggcccacctg ggtccgaccc tgttcgcgga
    12541 ggaactcctg ccgtgcccgt cggagggcgg cctgagcggg ccgcgcgggc ggcacgccac
    12601 ggaggtgttc ctcgaactgt ccaccgtgcc ctcccccgtc cctccgatgc ccgttccccc
    12661 aggcgaagtg aggctggtcc cttgaccgtc ggactccgag tgacctacta cgacagcgac
    12721 aagggcgcgc tgctgggcga gtgcctggta ccggccgccc tggagacctc ccgaagggag
    12781 gggatcaccg ccgcctggct ccacctgcac tggcggctgg gtccgcactg cgtgctctac
    12841 gcggacggcg acgccgaagc cgtggacgcc gcgctgcgcg acgcggacgt ccgcgtacgg
    12901 gggttcctgg aacgcgagcc ttccacgtac gcgatcgacc ccggccagta cgcggacttc
    12961 tccgcgagga tgggccgcat ggagctggtg gagccgccct acgcaccgct ggaaccggac
    13021 aactcggtcc ggcggctgga gggggacccg gtggacacgt tcctgcgcgg gcgcgaggcg
    13081 gccgagctca agggccgggt gctgaccgac gggctctccc gggtggccgg cctggtcggc
    13141 ggccgggccg acggaggggc ggcggcctcc cacgtgttcg cggggatggg cgcgatcgcc
    13201 tcccagtacc ccgagtgggg actgcgctcc ggctaccagg cgttcctgtc gcactggaag
    13261 gagtacttcc actggtcgga ccccgacggg agggcgcagg cgcggctcgc cgagtcctac
    13321 ctggcacagc gggaggatct ggtggaaacg ctgcgcgcgg tccacgaggg caccacggac
    13381 gacccgtccg cgctgtcctg gctggagtgg acgcggcggt ggctgcccga ggcggtggcc
    13441 ctggcgcgcg gggagcacat cctgccgttc ccgcacccgg accgtctgga cacggcgacc
    13501 cgcttcggcg aggacacgcg gatccggtgg agcggctcgg acgagcgctc ctacagcgac
    13561 ttccaccggg agttccgcaa gctggacttc acccggctgg gcgacgggta cgggttcgcg
    13621 gcgttccggt tcgtcatcaa ctgcttcttc gacctgctgc ccctgatggg ggtgtcgccg
    13681 atccagcggt actcgatcgc gtacctgttc accgaggccg cccaggaggt ggtgggcgag
    13741 acctgggagg agaccgtgcg ccgggtggtc gaccaccaga gcagcgaccc ggagctgaag
    13801 ccgaccctgc cgtgggtggg cgatgcctga acacaccgcc acgcctgagc acaccgtcac
    13861 gcgccggctg aagagcgccg tgcgcgcccg ctccctcgcc gaggaggggg tcgccctgag
    13921 catgggggcg accgccgtcg tggtgcgggg cgcccgggcc gacaccgtgt ggcgcgccct
    13981 ggagcccgcg ctgcgcgccg ggttcacccg gcgggccctg accgagcggt tcccggccgg
    14041 gggcaggccg ttcctggagg gcgtcctgga ccaactggag gagcacgggt tcctgcggga
    14101 ggcggaggag gagcacgggc tgtcggagtc cgagctggcc gcctacccgc acgtggagtc
    14161 gctgaccgcg cggccgtacg cggcgctgcg cgcgctcgcg gagagcaccg tccggatccg
    14221 gtcgtcctgt ccgctgctcg aagcggaggt gcgccgtgcc ctggggcgcg ccggtttccg
    14281 cgaggtacac gccgacaccg ggcccggcac cggcgcgctg ctgaccacca ggctctccgt
    14341 gcccgggcgg gaggaggcgc tgcacctggt cgacaccgaa cgcggggtgt gggtctcggg
    14401 cccgcgcaac acgtccggcg gccccgagct ggtggaccgt gtgcgggcct ggttcggggg
    14461 gcacggcgct ctcggggccc ccgaggcgag tggtgccgcc gagacctccg agggctctgg
    14521 gggctctggg gtttccgggg tccctggggc gtccgggaac gaggagagcc ccgggctggc
    14581 gatcacacgt tccctggtgg ccgcccaact ggcgctggcc ctggtcgcgc aggtggcccg
    14641 gagcgtggac gcggcggagc ccccgggcga tccggagttc atggtgacca cggacgagct
    14701 ggtcagcgag ccgcatccgt tcgtcgccct gcccgccctg gacccgcgcg tcgaggcacc
    14761 ccttcccacg ggagccgtgc ccgcggagga ggtgcccgaa cgactggacg cggtggcgca
    14821 cctgtgggac cgggtgttcg gcccggtcgg cgaaccccgg ccggacgacc tggagcagtt
    14881 gcccgtggga ctggcccggg tggagcgctc ttccctcctc ggcgcgggta ccaccaccgc
    14941 gtcggcccga ctggacgcgc tgaccaccgc gctgcacgcc gtcgcccggc cggagggatc
    15001 cggccgcgga acgggagacg gtggtcgtgc ccgggccggt gatcccgggt tcgggctggg
    15061 gctgaccccg tcggcggcgg tgggcgaggc cgtcggagac ctggtggtgc gcgtccgcga
    15121 ccgctggaag gacgtggacc ggccggaacc gatgtcggcg tccgcccgca ggctgtgggc
    15181 cgcgctgaca ctgcgtttcg gggtcggggc gcggctgctc tgccaggagc tggacggcac
    15241 cgccctgtgc cgggtcaccg ttctcggccc cggcgaggag cccatgggcg tcagcgccgc
    15301 tcccgacgtc gacgccgcga cacgggaggc cctgctccgc gccgtcgccc gcgtccaggc
    15361 cgcgcgggac ggggcggccg gcggtgcttc cggggacacc gcgtccgccg gatccgcgga
    15421 ggagaccgtg gccgtgacgg cgacgaggac cgaggcggtg accgcgtccc tggcgcggtg
    15481 ggcgcgcgag accggcctgg ttcgggtgta cgcgcccggc ggggccgatg cctgggcgga
    15541 gcgcggtgtg tacacggcgg tggcctcatg gacctgacca cacggaacca ggggaaccaa
    15601 cgggtctcac ctgaggggcg agaccagcga gacccgcagg accggcaggg tcagcaggac
    15661 caccgggacc agcggaccgc gcatgaggag cgggaccaac gggaccagag gtccgcacgt
    15721 gaaaagcgag gccagcggga cgggcgcgtc cgtgcccggg tcccgtcccc cgtgggggcg
    15781 acgctggccg agccccgcac cctccgtacg ggcgggggcc tgctgcacgt ggcgatgagc
    15841 ggcgcgctcg cggtcgtcgg accgtggacc cccgacgcgt ccacgggctg tgcgcggtgc
    15901 gccgggctct ggcgccggga cgtggagggc gacaccgccc ccgaccggcc cgtccccgag
    15961 ctcttccccc tgtgggcgga cgccttcgcc ggcctggccg aaaccgccgc acacggcccc
    16021 gaggacctgc ggctggcgct ggtcgccctg gactgccgca ccggcgaggt cacccggcac
    16081 cgtctcgtcc cgcacccggg ctgttcgcac tgctttcccg ggggcgccgg actcgccgtc
    16141 cccggcggcc tggacctgcg gaccccgagg ccggtcgccg gcgacgccct gcgcacacgc
    16201 tccatggacc gcgccggcct gcgggcgcgg ctcctggact ttcgcttcgg acccgccgcc
    16261 cacgtctacc gggacgagga gtcaccgctg tccctcatga cctgcgagac cgtcgccccc
    16321 ggccacacca ggcgcgaggg cggctacggg cgctccaccc ggttctccga cagcgaggtc
    16381 cccgccttcc tcgaaggcgt cgaacgcgtc accggcggcc accggcacac cggcgcggcc
    16441 acggtcttcg gcagctacgc cgaactcgcc gacgacgccc tcgaccccga acggctcggc
    16501 ctgcacgaac ccgagtggta cgggcacccg gtcttcgacc tggtccccta ctcccccgac
    16561 gtccccacct cctgggtctg gggctggtcc accctggagc gccgccggat cctggtgccc
    16621 gagcatgtcg cgtactggca cgcgggtacc gagggcaccc gcttcctgta cgagtcctcc
    16681 aacggctgcg cggtcggcgg gaccctggag gaggccgtcc tctacggact gttcgaggtg
    16741 gtggagcgcg acgcgttcct gctcgcctgg tactcgcgca cacggctgcg cgagatcgag
    16801 gcggaccccg gcctcgccca cctgaccgac ctgctggacg agcgcggcct gcacctgcgg
    16861 ctgctcgacc tcacctccga cctggggatc cccacggcgc tggcggtggt caccgccccg
    16921 gaggaggcgg tgcgctcggg gctggcaccg gcgctgagcc tggccaccgg cacccacctc
    16981 gacccccggc gcgcggtcat ggcggcggtg gaggagaccg ccaccaacgc gctcatgtac
    17041 cccaagtggg tgcggatgcg cgcgtcggtc gacgtggagc gctgccgccc catgctggag
    17101 gacttcaccc tggtcaggac actggaggac cacaccggaa tgcacgggct gtgggagtcg
    17161 cgccggcact gggagttcct gggggccccg accgccaccg tcccgatgga ggggttcgcc
    17221 gcgggccgcc cctcctcctt cgccggggcc gacctcaccg ccctgctccg cgaacgcctc
    17281 gacgccgtgc acgcgctcgg gctggacgtg gtcgtggtgg accagagcag cgccccgtac
    17341 acggacgccg ccggggtccg ctcggtgaag gtgatcgtcc ccggagccct gccgatgacc
    17401 ttcggccaca cccaccgccg tacccgctcc ctggagcggc tgacccgcgc ttccacgctg
    17461 ttcgagggag gagtcccatg ggaacgacac ggccaggtcc acccggtacc gcaccccttc
    17521 ccgtgaccgg tccccgccct cccgcgaccg actcccgggc ccgggtcctg gccgggttcc
    17581 acggccagtc gcacgacaag gacgtctccc cggtggagac cctgttcttc gggccggacc
    17641 tgtccaacgg cctggcccgg cccgtacccg ggcaggcccg cccgagtctg cccgccctgg
    17701 gcccgctgcg ggacacgaac gcctccgggc ccccgctcgg cggcccctgg tcccgcgcgc
    17761 agcggctgct cgccgcgtgc gtggaggcgg tgcgggtgcg ccggatctcg gcggccgacc
    17821 gctacccggt gcaccgcgcc tacccgtccc cgcgcgggct cttcggcgcc gacctgttcg
    17881 tggtctccgg cggtcccgta ccccggtgcc tgcgcgtgga cccgcagtcg cacgcgctcc
    17941 agcccctgga cggcctgccc gcgccgaggg agccggagga cctcgccgac gcacgcctgg
    18001 tcgtggcggt ggaccaccgc cgctacccgc ccgagtacgg gcggctgcgc ccctcgctcg
    18061 ccctgctgga gggcggacac ctgctggcga cgctcggtct ggccctggaa cgcgccggtc
    18121 tgcgtccccg cacgcacttc ggtcccaccg acaccccggt gcccagcggt ttctcgccct
    18181 gcggcgccat caccctggag ccggacggga cctccgacgc ggacggggca ggcgaggctc
    18241 ccgaggcggg cagcgctccg gaaacagaag ggaccacaga agcaggcggc actccggaaa
    18301 cggaagggac cactaaggca ggcggcactc ccaaggtgag cggcgctccg gaaacggaag
    18361 gggccacgga gccggacggg ttccccgagg ctgacgggac ccctacggac accgcgccga
    18421 cggtgtcggc cgaggcgctg tcccgggtgg cagccgcctc cgcgccgacg ggcaccgcgc
    18481 tgcgccgctg gctcgacgac cgcaccagcg gggtgtccac cgccaacctg gtcaccagct
    18541 cccacgtcgg ccccggcggg ggcgagggcg tcagcaccgc cctcgcggcc gccctcggcg
    18601 ccgccgggga ggccctcccc gtacccggcg cgctccgcct gtaccggaag gtcctcgtgg
    18661 cggaccgggt ggacgaccgc gccgcttgcg aactcgtgcc cgacggcacc gaactcccct
    18721 cccggcccgt ggcgcgcacc ggggagacca acttctcctc ctccctcggc tacacgctcg
    18781 ccgtggactt ccgcccgtgg gcgcgtgccc acggcgacca cgcccagacc gtcctgcaca
    18841 ccctcctcgg ctggaccgcg cagtggggct gcctcggcgc cgccgccacc gggctgtgcg
    18901 cccggcccat gcgcaactac caggaggccg actgggcggc cgtgctcggg ctcggccccg
    18961 accagacccc cgcctaccag ttgtgggtgc gcgccgaacg cggctcctac atggaccttc
    19021 cagtcgacgc ctccccctga ccccgtccgc ccggcccccg tgtccgggcg ggagaccccc
    19081 gaagccaagg aagagcagcc accgtgaccc gtacctggtc ggccgtgtac gtccacctcc
    19141 accgcgagcg cgagcacctc gacgccttcc tgctggacca cctggccccg cgcgcggagg
    19201 aactggtggc gcggggccgc gccaaggcgt ggttcttcct gcggtactgg gacggcggcc
    19261 cccacctgcg ggtgcgcttc ctcgacgcgg acgccgacgc cgtcgacgcg ttctccgagc
    19321 acatgcgcgc cgccgcggcg gagaccgccg acgacgcggt cgccctggac agcgcggcct
    19381 actacgcgaa cctgccgcag gccgaccccg gccgctggca cggtgacggc gacgtggtcg
    19441 gggccgtcta cgagcccgag accgggcgct acggcggccc ggaggcgctg gaggtgtgcg
    19501 aggacttctt ctgcgtcagc tccgccatcg cactcgccgt cctgcgctcc gcgccacagc
    19561 cgcaccagcg ccaggcggtg gccgccgacc tggcgtcgct ggccttctcc gtgctcgggt
    19621 tctcggacgt ggaggcggtc cgccaggccc gcggctacca cgccgcctgg gactactccg
    19681 ccgaggtcgc ccggggagac ggccgtgccc gcgaggaggc cgagcacctg ttccactcct
    19741 cgccctcacg ctggctccag cgccgcacgc aactggagcg cctggtctcc gccgacggct
    19801 cctccaccca ccacctgtgg caccgtgcgc tcggcgagac cgtggcgaag ctgcgccgtc
    19861 tgcacgcgga gcagccgctc accaacgccc tcacccgcat cgtgtggtcc ctgctgcaca
    19921 tgcaccacaa ccgcatcggc ctggacatcg acgacgagcg acgcatcgcc tggctcctgt
    19981 cactgtccta tccgcggtgg gagcccgccg gggacttctt cgcgcccggg gtggcctcgc
    20041 ccgaccgggc gtacgcggag gcgagcaagt accggacggc gaccatcggc ggcgagcacc
    20101 tgccccggcc ggtaccgcac gaggaggggc tctccccggc ctccgccccc tcccacgcgg
    20161 gccttccggt ggtgggcctg cccgctcccg gcccgctgac cgccccggtc ggcgacgtgc
    20221 tggaccagcg gtacagcacg cacggcgact acggctcccg catgtccctg gcggacctgt
    20281 cgtccctcct ggggcacgcc gccggggtca gccgcgcccg ctccggcgag cccggccgcc
    20341 gccggccgcc gcgcaaccac ccgagcccgg gtgcggccta cgccacgcag gtgtgggtgg
    20401 tcgcccggca cgtggagggg ctggaccggg gcacctaccg ctaccgtgcc gaggaacacg
    20461 ccctggtccg ggcggacggc gccgcggccg ccgaccggct ggcggagctg tccccgttcc
    20521 tgcgggggtc ggccgacggc cgcccggggg ccgtggcgga cacggtggga gcactgctgg
    20581 tgctggtggg ggacctgggg aggctgcggg aggggtacgg ccagcgcgcc ctgcgcctgc
    20641 tcctacagga ggccgggcac gtggcgcaga acctgtccct gtgcgcgacg gcgctggggc
    20701 tgcggagcct ggtggtgtcg gggttcgccg acgacgcggt gaacgcccgg ctgcacctgg
    20761 acggcgtgga ccggatcgcg ctgacgctgt tgccggtggg ctcaaagccc tcccctgcct
    20821 aggtaccgcg gagcacggtg ggtccggggc cgcgccccca ctgtggcgtt cggaagtgct
    20881 ggatcggcgt ctccggcccc gtctcctcct cgcacaccgt ggcaccgtgc ccgcaagctg
    20941 aaccacggga tctacggttc acgcgtcttt ggagtcggaa cccattcgtc gtccaggatc
    21001 gagtgaacga cggaatcgcg ccatgcgtcc cgggtccaca gatgtcgacg gatgcgccct
    21061 tcctcgacca ttccggctct gagcatgacg cgctcagaag cccggttctc cggagaccga
    21121 gcaccccata tccgtttgag ccccaggcgg tcgaagccga gtcggagaag gagtccgacg
    21181 agttcactgc cgaagccttg cccccacaga tccgtgcgga gggcgaaccc gatctgagcg
    21241 ctgtgggggc gttcgtccac ggccaagcgc gcggtgccaa cgagatggtc cttctgcact
    21301 gcggcgagca tgtagacgct gcggtctccc cgcccggcgt cggagaccgc ggcctcgatg
    21361 agcgcagcgc actgttcctt ggtgcgtggt gtgaacgaca ggtgctcgac ggccttccgg
    21421 tcaccgtaga ccttgaccag gtcatcgaca tcggtcggac gtagctcacg cagggtgagc
    21481 ctgtcactgg agagttcgac tggatacatg accggcaggt tagcgacccg aggttcgggt
    21541 cggctctgaa gtgctggctg gatcggcgtc tccgccatgt ctcctcctcg cacaccgtga
    21601 catcgtgccc acaggacagg cggacggcag gaacagcagc gccccggaca tggctaatcc
    21661 gggggcgcgg cgaagaggag gcttactgga gggggcctgc cttgagatca tgaaggaagg
    21721 aggtccactc tgcgggcgaa tactcgatgt ggcccagctc gcggttctgg gtgtcacgca
    21781 cgaagaccgt gtcgccttcg gcgacctcaa cgcactcggc gccgctccca ccgctgtagg
    21841 aactcttgtg ccacggacgg tgatggctca tagctctccc tgttctagct gccgaaccag
    21901 ctctaggctg tcatgcggtg acagcgcttc accttgaagt cttccgtata cgctgacggc
    21961 tttgcgtatc tggtccgggt cctcgatgag tacttcatcg aaggcgtgct cggcggacac
    22021 cactgtttga tcttctagga ccatgatccg gaaccctcct ggaaagcctg gatgctcccg
    22081 gggcgtccgg ggcagaacct ggaagcgaac ccagcgcttc ccgatcacgt ccacgaggtg
    22141 agcgagctgc gcccgcatgg cgggcacgcc tcccacgagg cgccgaagca cggactcctc
    22201 aacgactacg catactatcg gccgctcaag tcggttgaat attttctgtc tctgcaagcg
    22261 accttgcact aggcgttcga tcgtctcttc gtcggcctgg gggcggtcag ccgcgaagag
    22321 agctttcgcg tattcgggtg cctggacgag cccaggaacg agaacgggct ggtagaagcg
    22381 cagttcgagg gcttccttct cgatgtccac aaccttgcgg aaccctactg gcacgagtcc
    22441 gtggttggag catctctccc atgactggag aagcttccct ttggcaccca aagctgcgtc
    22501 gatcttcgca gcatggtcat cctttgggga catcttcccg ttctcgacgt acgacagtga
    22561 ggcttctgaa aggccgacca gaggagctag atccttcagc gtaagcttgg ctgccttcct
    22621 ccatttacgc acgtcagagc catacttccc ccatatcggg ctgatctttt ttaagcccat
    22681 caagcctcct tcgcatgagc tgatcaccct gtccagcagg atcggcatcg acgttgcttc
    22741 acccgtactt caccaggaac ctaagtcctt caactaactt gggcgaaggt tgaagactct
    22801 ggacaccgag accgctcgca gatcatcgtt tccagtgaag cactcaaacg gaatctagct
    22861 ggttgcgcca acaaggagag cactgggcac cgaaatcgca acgggaacgg ttgcgacaaa
    22921 aggtgtaatc agaccttacg ggtcgagcct gaggcgttga agacttggct ctcttcctgg
    22981 atgcccaacc atgcattcaa ctactcaggg tgacgaccta agaagaaagg gcgacgatgg
    23041 cgatggtgat cgacatggat gagaagcggt cgggcggccc tagggaacaa gcccctgacc
    23101 ggctcccccg tcgcctcggt gactcgcgct cgaatgcgcc cctggccttc gatgagggcc
    23161 gccctcactt gggtgccgcg atggtcctcc ctggagagcc ggaccaggtc gccgtcatgc
    23221 ggcgccgtat ccgctcgcgc accaacggac acagccccga gactgacgcc gtggtgctcc
    23281 tggcgagcga gttgttcacc aactctctgc gtcattccca cagtggtggc cccggggaga
    23341 ggtgaccgtg tcagtgttca agctccccgg tcgctatcag gtacgtgtca cagaccaggg
    23401 accgcgagag agcgaggaag gtatctcctt tccctacctc cgcgcctcgg atccgctcag
    23461 cgagggcggg ttcggtctgc gcctggtcgc gaacgaagcc agccgctggg gcacgatcca
    23521 cgagaacggc cggaccacgg tgtggttcga gctcgaccgc gtccctctca ccctcagctc
    23581 gtgaggccgc catgggctgg acacacgcag acgaccaacc tgcctacgac gccgcccgag
    23641 aactccagca ccacgtcggc cctcgatggc tcgtgttctg gggacccgcg tcgcgaagct
    23701 tctggggctt cctgcgcgga ggcccccacc ccctgatact gagcgccccc acggcacggg
    23761 gcctcgtgga caagatccaa cggcaccgac gatgaacgag aaagcgagcg gatggttctc
    23821 ctgtgcgggc actgcggcaa cccacgcgag ggcggagcgc cgacctaccg ctgcacctgc
    23881 atccccgccc acgtgtggga agaacccgat cttgcccagg ccgtacgcac cctgaacctg
    23941 tccgaggtca tccgatgcat gcgccaacac cccgacacac gacacctgtc ccaagtagct
    24001 ctggccacca tgtccggcct gtcgcaggcg atggtctcgc gcctggagaa cggcgtgaac
    24061 gtcgccagca tcaaccgcgc cgtcgacgcc ctggcgggcc ttggagcacc cggggccgcg
    24121 gacgggaaac ggtggcgact gcccgacgac agcgagcctc tgcccccggc caagcctcaa
    24181 atgactccag gcgtgccgtg tgtggtcatc accagccccg tccccatcta cgtgcaggtg
    24241 atggacccac ccgacccctc caccacagga accaaccgtc acagcgatgt cgccttcgtc
    24301 atcgacacgg acggtccgcg cctgatcgtc aaccaagaca tcccctgggg cgtgaccagc
    24361 gcccctggcg gagctaccgc atggttcgcc ctcaccgacc gcgaacagca catcacgacc
    24421 gcccacgagt tgaaagcccg aacatgaccc cctccgacct gctcgaaacc cccgctgggg
    24481 aaatgacctc cgtggcaaag cgaacgaagc ctcccggttc cgcagacacc atccgagcga
    24541 acctgggaga agcctcacac cgacacggcg tgaggtaccc gagaaggaag gaattccaca
    24601 tgtcccccaa gaacctctcg actctgctgg agtcgcccga cggcgagtct cgcgcggaga
    24661 tcgcccgact cggcgacgct tttcccctcg acccgtccac ggccatcttc gaggccagcg
    24721 acgaggcccc gacccaggtc cgcccgtggg gtctgcggcg cgcggtcacc ccgaagctgc
    24781 gccccgaggt ggccgaagcg gtggaccgct tcgtctacga ccccgtgacc cagcagggca
    24841 ccgaccgcat caccggagca ccggcggtcg gcaagcgctc cagcggcacg aaggagacca
    24901 ccggcgaccc cgacggaagc cgcccgacag ccgaggagac cacctccgac tgatggtctc
    24961 ctcggctgca cggaaggcgg tgctcgtcct caccaacacc gaggacggca ccgccgaccc
    25021 cgtgatccac cacctgtcgg aacgcggcgt gcccgtcgtg cgtatggacc ctggtgactt
    25081 cccggcctcg atgaccgtcg aagccgcctt cgatggcgag cactgggagg gagcggtcca
    25141 cgacgccttc cgcggagtgg acctgggctc ggtgcgcagt gtctactacc ggcgtccctc
    25201 ccagttcacg ttggccgaag gcatgtccgg ccccgaccag cgctgggcct atcgtgaagc
    25261 ccgcatggga ttcggcggtg tcctactggc actggactgc ctgtggatca accagccgtc
    25321 gcgcatgagc gcggccgagt acaaacccgt tcagctcgcg acagcggcca gggccgggct
    25381 gagggttccg cgcacgatca tcacgaacgt gcccggccac gctgcagact gggccgctgg
    25441 tatctccggc cccgtcgtgt acaaaccgat cggtggcgcc ctgcacgtcg agcaggggcg
    25501 cacctggatc gtctacgcca acgcggtcgc cgccgtcgaa gaactccgcg accccgccgt
    25561 gggcctgacc gcccactgct tccaggaatg ggtggacaaa gcgttcgagg tccgcctgac
    25621 gatcgtgggc aaggcgatgt ccgccgtggc gatccacgcc cgatcccagg ccgcgcacat
    25681 cgactggcgc agcgactatg gcgcccaccg gtacgaggtc gtcgacgttc ccgacgctgt
    25741 ccgcttcggc ctggagcgct acatgcacgc gttcgggctc gtctacggcg ccgctgactt
    25801 cgtggtctca cccgatggga ggtggacctt gctggaggtc aaccccaacg gcgaatgggg
    25861 gtggctggcg gaccattgcg gcctgcctgt cggacagagc atcgccgcac tactggagaa
    25921 gggacagatg tgaccagagc tgttcacgaa ctctcgtccg ggctcaccgc tcacatgatc
    25981 gaggagggcg tactggtgcc aggagaccgc cttaccgagg cgttccggcg tgtggaccgg
    26041 ggggtgttcg ttccggcctt cgccctgcac gagcacacct cgcagggcgt gcgctacagg
    26101 ctcgtgcggg gtgaggtccc cgagcagcac gaggcgtggg ctcgtcatgt ctacgccgat
    26161 gagacgctga tcatcgagat cgccggagaa ccggtcatcg acgccctgcc cgggggcacg
    26221 ggcacaggcc ggtggaccag ctcctccacg atgcccagcc tcatggtgcg gatgctccac
    26281 cagctcgacc tggatggcga ccctcgcgtc ctggaagtcg gggtcggctc gggatacaac
    26341 gccgcgatcc tgtgcgaagt cctgggctcg gaccgtgtca cgagcatcga catctcaccg
    26401 cgtctggcct tcgacgccac ccaacgcctc tccgctctgg ggtacacacc ggtcgtggcc
    26461 gagtatgacg gccacaaggg ttttcccgac cgtgctccgt acgatcggat catcagcacc
    26521 acggccttca cccacgttcc accggagtgg atccggcaga cggctcccga gggagacatc
    26581 ctcgtcaaca tcgcgggtgg gaccggagga gccatgctca aactccaggt gcgcgacgac
    26641 cacaccgcgc agggacgctt catcccgcag tgggcggggt tcatgcccgc acggagcgag
    26701 accccccggc agcgcgtcac cgtggacgac gcgggtgagc agagcacgac cgcgctgaac
    26761 cccgcggtcg tgcgcgagga accggccatg gcattcctgg cgcaactggc cacgacggac
    26821 gccgacaccg ttctcaggac agccgatgac ggcgctgact tcctcttcat ggaaggcgcc
    26881 gacggggcct gggccgagat cgacacggac acagtcaatg gccgccaccc ggtggttcag
    26941 ggtggtccgc gccgtctgtg gaaccaggta gagaacgcgc accactggtg gctcgccaac
    27001 ggtcagccgg actggagcgc cttcggagcc accgtcatac ctgaagaaca gcacgtgtgg
    27061 ttcggctctc cggagagcga ccagcgctgg ccactgccac atccgcggtg accgccccgc
    27121 agtggtcaca cgcgatgggg ccttgcccgg tcacctgggt gaggtccttg tgccgcacga
    27181 gggacacgcc tccgaccgca gggcccggtc ttggacagag ctcacgggct cgggatcaag
    27241 acgtggaggt cgccatgcgg tcggctcgca ccacggagcc gtcgcgaaac cgatccttcc
    27301 ctaaccagtc cagtcagtcc ttcagcaggg ctacctggaa ccgtttacgc acgaattgag
    27361 gacaagccat gttcaccatg cgtctcgcca ccgaggccga cacccctgcg gtcacgtcga
    27421 tgatcacagc gcgctgtggc tggatggagc agcaggggtt ggagtcgtgg cgtgagaaca
    27481 tcgacgacct cgccgggcag tccgggagcg gcttcatgtg ggtactcgaa ttcgagggca
    27541 gcatcgtcgg atgcaccacg gtcatgaccc aggcaccgcc caaggactgg acacctgagg
    27601 aggcggacga accagccctg tacttgttca cgaccgtgac cgatcccgcg taccaggaac
    27661 acaaacctgg aaccctgatc gcgctgtggg ccgtcgaccg ggccgcacga cagggacgta
    27721 cctgggtcag gcggggatgc ttcttccctg agttggtcaa gtactacgag acccaggggt
    27781 acagcctggt caaggaacag aaccgaagtg ccgggcacct gtacctactc gcacgccgag
    27841 cggaacgtct cgaccttgaa gctctcggga tggaaaccag gaccacagcc tgacactgga
    27901 agtgaggaag gcgccccgtt actccatatg ggaggcacga aggcattcgt ctggggaagg
    27961 tccacccacc cagacagcgc tggtgacacc aactgcgtcg aggtcgccgg tggagcccct
    28021 accgctgtgc gggacacgca gaaccgggag cagggacacc cagcgttcgc ggccgccgag
    28081 tgggccgtgc ccgtggatac cctcagggac cacgactggc caccgggccc caaggcggta
    28141 ctcccccacg ggaggccacc ctctttcgtg tcctcacatg gcgatgggcg ccttgagcaa
    28201 atgtcatcaa ttctgacatt gaggactgtt tggaaagaat gacagaggag caaaattcct
    28261 tttctgtccg ccctgaactg cgaacatggc gaacaccaga gattacccag gggtaactcg
    28321 cagaaaggtt cgcatccgct ccagtcctgc tctaatctgg cagcgttccc acaactcaat
    28381 ccacacaatg accccgcgac ggttagcacc gtccggggcc gtggccagca acttccaccc
    28441 tttaacgaca aggattgcca gcatgcgcaa gtttagcgct gcggccctga tccgtgccat
    28501 cggcacggcc aaggccctct tcgcctcccc gtgcggacgc cactcctccg tctgcggccg
    28561 tcgccgccgc tccacccggg tccgccgcta cgtcccggtt cccgccccgg tcgaggacac
    28621 cgcacctccc gcgcctccca tgcgaaccga ccgggccccc gagcgcccca ggctccccgc
    28681 tcccgtcccc gcgccccgcc tggctccgcc gagcgagcgg ttccccgccg acgagatcgc
    28741 cctggtccgc ccctactacg aggcccggga gcgcgaactc gcgcgcgttc gggccacggc
    28801 gaccacccgc ccgcaccgct ggaccggtga ggacgtcccg ccccgcggcg acctcctcgc
    28861 ggccggaccc ttcccggctc cgagccccga accccttccc gtacccgccc cgcgcgcccc
    28921 gtcgcccgca tgcgaggacc ccgaggactg gcgtacgctc acccgcctca cccgtgtctg
    28981 gctcgaccaa cagcgacggc ggacgcagca gcccacgcag cggtccgggc agcggcacca
    29041 ccggcaggcg gtcccggcat gaccttcctg tccatgccca aggtgcccag gcccctcgtg
    29101 ttctgggagc accgcgtcta cccggggacg ctggaccagc tcgcgcgggt ccgcgcggaa
    29161 ctcgcgacgg acctggccgg tttcgacgag gacctcgtcg agaccgtgcg gctgtgcgcg
    29221 agcgaactct tcgcgaactc cgtcaagtac accgactcgg gcggacggga cggcgaggtc
    29281 ctgcgcgcgc tgtcgatgcc ggacgcgcgg accctgcggt tctcggtgag cgactgcggt
    29341 ggagggggcg gcgtcccggc cgtcccggag gaacggacag aggacgagtg gagctgggcc
    29401 gagggccggc gcggtctgct cctggtcgag aacctgtcca ggcggtgggg ccacttccgg
    29461 ctcgcgccct gggcggatct gggcacccac gtctgggccg tcttcgacgt ggaggcgggc
    29521 gcggccccgc ccgacccgcg ccccacgtct tcaccggcgc ggccggttga acgaggacag
    29581 ggcggggagg cggtgggcct tcgcctcccc gacccgcgcc acgcccatgg gagcgcttcc
    29641 ataggatgtc ccgtatatgc ccccttctcc gccgacggga ccttcggcac ccttccgtat
    29701 cccttgggac acaagtccct gccccccact ggcgcctgtg gctactcggt agtaacattg
    29761 gcttgttact agtcggtaga tccgcgtgta cagacaccgc ggccgggaca cacagcggag
    29821 ctgtccatga cgcattacaa gagcaacctg cgcgacatcg agttcaacct cttcgaggtc
    29881 ttcaggcgcc aggacgtact gggcaaggcc cccttcgagg aactcgacga ggagaccgcc
    29941 cgcacgatcc tggacgaggt caaccgcctc gccaccggtg tcgtcgccga gtccttcgag
    30001 gacgcggacc gcaacccccc ggtcttcgac ccgaagacga acaccgtcgc catccccgag
    30061 agcctgaaga agtcctacca ggcctacatg gacgccggct ggtacaacct cgacctcccc
    30121 caggagctcg gcggcctcgg cgccccccgc tccctggtct ggtccgccgc cgagctggtc
    30181 ctcggctcca accccgccgt ccacatgtac tcggccggtc ccggcttcgc gagcatcctc
    30241 tactccgagg gcaacgagaa gcagaaggag ttcgccaagc tcgccatcga gcgcggctgg
    30301 ggcgccacca tggtcctgac cgagccggac gcgggctcgg acgtcggcgc gggccgcacc
    30361 aaggccgtcg accagggcga cggcacctgg cacatcgagg gcgtgaagcg cttcatcacc
    30421 tcggccgagc acgacatgtc cgagaacatc ttccacctgg tgctcgcccg ccccgagggc
    30481 gcgcgcgccg gcaccaaggg cctctcgctc tacctggtgc ccaagttcct ggtcaacgag
    30541 gacggctccc tcggtgagcg caacggcgcc tacgtgacca acgtcgagca caagatgggc
    30601 ctcaaggcct ccaccacctg cgagctgacc ttcggcgaca agcaccccgc catcggctac
    30661 ctcgtgggcg acaagcacga cggcatccgc cagatgttcc tcatcatcga gtacgcgcgc
    30721 atgatggtcg ggacgaaggc gatcgccacc ctgtccacgg gttacctcaa cgcgctggag
    30781 tacgccaagg agcgcgtgca gggcaacgac ctggccgggg ac
//
