LOCUS       NZ_CP014263            20972 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Spirosoma montaniterrae strain DY10 chromosome, complete genome.
ACCESSION   NZ_CP014263
VERSION     NZ_CP014263.1
KEYWORDS    RefSeq.
SOURCE      Spirosoma montaniterrae
  ORGANISM  Spirosoma montaniterrae
            Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae;
            Spirosoma.
REFERENCE   1  (bases 1 to 5797678)
  AUTHORS   Kim,M.K., Srinivasan,S. and Lee,J.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2016) Department of Bio & Environmental
            Technology, Seoul Women's University, 623 Hwarangno, Nowon-gu, Seoul
            139-774, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PacBio SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 72.42
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 01:24:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,031
            CDSs (total)                      :: 4,981
            Genes (coding)                    :: 4,945
            CDSs (with protein)               :: 4,945
            Genes (RNA)                       :: 50
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 26 of 36
            Pseudo Genes (incomplete)         :: 12 of 36
            Pseudo Genes (internal stop)      :: 2 of 36
            Pseudo Genes (multiple problems)  :: 4 of 36
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:11:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5705885
            Orig. end                         :: 5726857
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014263.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20972
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="13"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20972
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20972
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10972](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10972
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    234..249
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.87"
                     /tool="antismash"
     misc_feature    complement(514..528)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.31"
                     /tool="antismash"
     gene            complement(623..1405)
                     /locus_tag="AWR27_RS24635"
                     /old_locus_tag="AWR27_24410"
     CDS             complement(623..1405)
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015331767.1"
                     /locus_tag="AWR27_RS24635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24410"
                     /product="FHA domain-containing protein"
                     /protein_id="WP_077133635.1"
                     /transl_table=11
                     /translation="MTFSTLTKPAIWFEQQLEQLSQLPVFTIGRGADNDIVVANPKISS
                     KHASLIQCTPTDFVLEDLDSKNGTFVNQQRIKRKLITDGDTIRLADVDYTTNQLLALRV
                     VPPANTPEQPVLPQPTASKPAPEAADSLDFSRQFSDLQTVYEQYPKLRRDCRNREKMIR
                     TGSVIVSSIVGVSAAIATGGGSIPILQIMSGAGLSMLVPTLCSTLLSTEEKLELIDKQY
                     RERYRCPNPTCRDPFGTREWDLLAQQKSCRRCQAIWVS"
     gene            1543..2304
                     /gene="kdsB"
                     /locus_tag="AWR27_RS24640"
                     /old_locus_tag="AWR27_24415"
     CDS             1543..2304
                     /EC_number="2.7.7.38"
                     /GO_function="GO:0008690 - 3-deoxy-manno-octulosonate
                     cytidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="kdsB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012927345.1"
                     /locus_tag="AWR27_RS24640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24415"
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="WP_077133636.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.6e-08, bitscore:
                     31.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIGIIPARYGSSRFPGKPLAQLNGKPMIQHVWERTSQARSLDRV
                     AIATDDERIASVARAFGADVLMTRPDHVSGTDRCYEAYNLLRPQLPPQSDAQHYVVNIQ
                     GDEPFIHPNQIDGLTVILDGAVEIATQCAKIDSATILHDTGEVKIALTKQGDALYFSRQ
                     PIPFLRGVDPAEWHTRYPYYQHVGLYAYRADILEQISQLPPSPLEQAESLEQLRWLEAG
                     YKVKLVETPYVSICVDTPADLEKISRIQGGV"
     gene            complement(2312..2659)
                     /locus_tag="AWR27_RS24645"
                     /old_locus_tag="AWR27_24420"
     CDS             complement(2312..2659)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012924856.1"
                     /locus_tag="AWR27_RS24645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24420"
                     /product="XisI protein"
                     /protein_id="WP_077133637.1"
                     /transl_table=11
                     /translation="MDSKVNTYRTLITELLTQYANAPAIFIGDDQVEEQLIIDAERDHY
                     QILTIGWENGKRVYYPVFHLDIKNGKIWVQEDATDFDIVGELERRGVSKDDIVLAFHAP
                     YKRPYTGYAVA"
     gene            complement(2644..3060)
                     /locus_tag="AWR27_RS24650"
                     /old_locus_tag="AWR27_24425"
     CDS             complement(2644..3060)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012924855.1"
                     /locus_tag="AWR27_RS24650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24425"
                     /product="element excision factor XisH family protein"
                     /protein_id="WP_077133638.1"
                     /transl_table=11
                     /translation="MARDIFHQVVREALEADGWLITHDPLILKLGGLRLEIDLAAEQVL
                     AAERGSEHIAVEVKSFLSKSKLSDFYQAKGQYDVYLIGLQEDRPSRKLFLAVDTDIYTS
                     FFQKPLIQKIVADYSISLLVFDANSKRIVQWIAR"
     gene            3272..6148
                     /gene="carB"
                     /locus_tag="AWR27_RS24655"
                     /old_locus_tag="AWR27_24430"
     CDS             3272..6148
                     /EC_number="6.3.5.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="carB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020601056.1"
                     /locus_tag="AWR27_RS24655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24430"
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="WP_077133639.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 5.7e-07, bitscore:
                     27.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2e-08, bitscore:
                     32.2, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4.3e-07, bitscore:
                     27.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKNSAIRSVLIIGSGPIVIGQACEFDYAGSQAARSIRDEGIEVS
                     LINSNPATIMTDPINADHVYLLPLEKKSIVEILKKHQDMGRPIDAVLPTMGGQTALNLA
                     IDCEKAGIWQKYGVKIIGVDIKAIETTEDREKFRLLMLQLGAGVCKGRTARSFLEGKEI
                     AQEIGFPLVIRPSFTLGGTGGGFVNTPEEFDKALTHGLHASPVHEVLVEQSVMGWKEYE
                     LELLRDNNGNFIIICSIENFDPMGIHTGDSITVAPAMTLPDTLYQQMRDLAIRVMGGIG
                     QFAGGCNIQFSVNPQTDDIIVIEVNPRVSRSSALASKATGYPIAKIAAKMAVGYNLDEL
                     INPITGTTSAFFEPAIDYVIVKVPRWNFDKFPGADRSLGLQMKSVGEAMGIGRNFQEAL
                     QKACQSLEIRRNGLGADGRELNDREALTKSLAHPSWNRLFHIYDAFKAGMSFRTIQQLT
                     KIDPWFLHQIEELILLEREIQQYDLDDLPPELLRTAKQKGYADRQLAHLLQVKESKIYQ
                     YRQQHNIRRVFKCVDTCAAEFEAKTPYYYSTFNNQLPITQDRPEPVSDLPGNESIRSNR
                     KKVVVLGSGPNRIGQGIEFDYSCVHGVLAAKEAGYETIMINCNPETVSTDPDIADKLYF
                     EPVFWEHVHAIIMHEQPEGVIVQLGGQTALKMAEKLTRYGIKIIGTSWEALDLAEDRGH
                     FSDMLRKLDIPYPKFGTVREAEAAIELSRELGFPLLVRPSYVLGGQSMKIVINEEELES
                     HVMKILQDIPDNNILLDHFLENAIEAEADAICDGEDVYIIGIMEHIEPAGIHSGDSYAV
                     LPPFDLSENVIRQIEEYTTKIAVALETKGLINIQFAIKNEQVYVIEANPRASRTVPFIC
                     KAYQEPYVNYATKVMLGDKKVKDFDFKPVKKGYAIKIPVFSFNKFPNVNKELGPEMKST
                     GEGIYFIDDLQDDFFQKVYSERNLYLSR"
     gene            complement(6262..7815)
                     /locus_tag="AWR27_RS24660"
                     /old_locus_tag="AWR27_24435"
     CDS             complement(6262..7815)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020601927.1"
                     /locus_tag="AWR27_RS24660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24435"
                     /product="DUF4394 domain-containing protein"
                     /protein_id="WP_077133640.1"
                     /transl_table=11
                     /translation="MRVLKNLRPVAALLAIGSLLMLNACKEEQLIDSRAELGAAQARLS
                     ANFTFYALTDNNQLLLLNSQNPTSALATTTITGLASGERLQSIDFRPATGQLYGVSDGS
                     RLYTINPNTGAARMVGMGPFMPPVAGDVVSIDFNPTVDRLRLVTNRGQNLRLNPETGTV
                     MVVDGSINGPAPVAINGVAYTNNRAGVTSTILYDIDPLTDKLYRQDPPNAGGLAEVGSL
                     GIDIAGRGSFDIAPDGSAVAILISGTTQGFYQIDLMSGRAERLSDLPNLSLIGIAIPTE
                     PVAYTVDGLNNLLIFNPLNPNPISKTITGLQNGETIFGIDFRPANGQLYALGSTNRLYT
                     INTSNGAAAPVGSGPFAASLSGNDRGFDFNPMVDRIRLVTNSGQNLRLNPNDGTVTAVD
                     GNLNPGSPNVTAAAYTNNFAGTTSTVLFDIDTRTENAMLMRQDPPNAGGLVAVGSLGIP
                     IEGGNGFDIGGTSNSAYALLRSGGTTRIYSINLTTGQASNGIALPGNPTVRGFALGLGF
                     "
     misc_feature    7878..7891
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.73"
                     /tool="antismash"
     gene            7949..8617
                     /locus_tag="AWR27_RS24665"
                     /old_locus_tag="AWR27_24440"
     CDS             7949..8617
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009284675.1"
                     /locus_tag="AWR27_RS24665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24440"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_077133641.1"
                     /transl_table=11
                     /translation="MEKLEDAPKFKFWKSQIEANGLTINGIKDHFIRRRHNGEVLFAML
                     ELDADTPEGDKIPPVCFLKGHAASVLVCLIDDQTGEKFVVLVKQRRISDGSQTYEHPAG
                     MVDAADDPADVAARELGEEIGLEATATELTKLNPRLWFPSTGTSDEAMHFFFIERTMPR
                     AEIMAFHHKNMGNHSEFERITTAVATLPEAHKLVNNVNGLLIHFLYLKHVGDYETMKRL
                     "
     gene            8622..9056
                     /locus_tag="AWR27_RS24670"
                     /old_locus_tag="AWR27_24445"
     CDS             8622..9056
                     /EC_number="3.5.4.33"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0052717 - tRNA-specific adenosine-34
                     deaminase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020600899.1"
                     /locus_tag="AWR27_RS24670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24445"
                     /product="nucleoside deaminase"
                     /protein_id="WP_077133642.1"
                     /transl_table=11
                     /translation="MDEFMQEAIRQARKSLDEGGIPIGSALVKNGALMASGHNKRVQED
                     NPILHGEMDCLNNAGRVGSFRDTVIYSTLMPCYMCAGTIVQFKIPKVIVGESRTFAGAR
                     EFMEQHGVEVVDLDLPECVAMMEQFIAEKPTLWNEDIGEL"
     gene            9125..9949
                     /locus_tag="AWR27_RS24675"
                     /old_locus_tag="AWR27_24450"
     CDS             9125..9949
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020607077.1"
                     /locus_tag="AWR27_RS24675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24450"
                     /product="hypothetical protein"
                     /protein_id="WP_077133643.1"
                     /transl_table=11
                     /translation="MKTRHRFCLLIVLLINHISTFAQRSAYWHEKPGTWLLNVGTGATR
                     YAGDLAEAGNLAHLQLGAALGVAGTYRATQRLSWRAEAQLYYVYGWQKYTRNYYNNLSF
                     NSLNPDVWAGIQFDFWPVNDPHRATIPYAMAGVGLTHITPKARYEGQNYSLPQFETEGV
                     AYNRLPLIIRYGVGLPMLSTERLRFHLEGTYTHVLSDYFDDVSSIYIDRSNMTPLGAAL
                     TDRRAELGTTLNRPGEQRGNTGKNDGYFVLSGRLVVVIITPQQRNYRRMFGR"
     gene            10001..10972
                     /locus_tag="AWR27_RS24680"
                     /old_locus_tag="AWR27_24455"
     CDS             10001..10972
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020607078.1"
                     /locus_tag="AWR27_RS24680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24455"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_077133644.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.3e-62, bitscore:
                     208.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPAVFIEAIQAELQRTKYGQYPPELYDPIRYIMSLGGKRMRPLL
                     TLMATYLFTDDWKQAIRPALGVEVFHNFTLMHDDIMDQAPLRRGQPTVHERWNANIAIL
                     SGDVMLVNAYELLLDVAPDKLKAVMSRFNRTAAEVCEGQQMDMNFETRWDVTEAEYIDM
                     IRLKTSVLLGYALELGGLIAGADAETNRHLYEGGVNIGIGFQLKDDLLDVYGDPAKFGK
                     QVGGDILANKKTFLLIEALEKATGPLNDELNGWLTKTEFDKAEKVQAVTAIYDQLGIRQ
                     ITEQRINAYFARGFANFDQLKADPTRRLLLTQFARQLVERES"
     gene            10980..11603
                     /locus_tag="AWR27_RS24685"
                     /old_locus_tag="AWR27_24460"
     CDS             10980..11603
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018617559.1"
                     /locus_tag="AWR27_RS24685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24460"
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="WP_077133645.1"
                     /transl_table=11
                     /translation="MNITLVIILVTVGVSLAAWNNPALMSRWIMNPYQVMNRGQYYRLL
                     TSGFLHADWGHLLFNMLSLYFFGGFIEQVFAYLFGGNGGLYLIGFYLVGIVVSDIPTLL
                     KHRNNPSYNSLGASGGVSAILFAAILFRPLTPIYLFFIPIGIPGFIFGALYLAYSYYEA
                     RRGYGNVNHDAHFYGAVFGVLFMIVVYPEVVPQFFDQVSGWRLF"
     gene            11607..12494
                     /locus_tag="AWR27_RS24690"
                     /old_locus_tag="AWR27_24465"
     CDS             11607..12494
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020600903.1"
                     /locus_tag="AWR27_RS24690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24465"
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="WP_077133646.1"
                     /transl_table=11
                     /translation="MFKLLAQPYPTEESLRRRLLKSFTIGAFVGLFLLLFQPFGIDDWQ
                     TDAKVWKVLGFGAVTLAVLLLNWFALPALFPRFFSDAQWTVGREIVRVLSFILAIAIGN
                     GLYMNWLFNRHPTIGSWLWIIGVTFLIGIFPTVGSIMLNYIIQLRRYSRSAATLNPVAH
                     NTAESTLQTETASPPPLSDTLTLLADNEKDTLTLEPAKLLFIESSDNYCTVVYLKNDKP
                     AKVLLRSSLSRMADQIQRPHIVRCHRSYIVNLDRVERVTGNAQGYKLHLLDGQFALPVS
                     RQYNDTLVAELKAL"
     gene            12631..13329
                     /locus_tag="AWR27_RS24695"
                     /old_locus_tag="AWR27_24470"
     CDS             12631..13329
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020600904.1"
                     /locus_tag="AWR27_RS24695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24470"
                     /product="DUF2306 domain-containing protein"
                     /protein_id="WP_077134191.1"
                     /transl_table=11
                     /translation="MNTLLTILLITHIATGFTALLVGLIPMFATKGSQLHNRAGLVFVY
                     CMIAVTLTALLLCVLQPFKMMRLFLTGIAVFSFYLSMTGWRATKQKNGQVAAFDHWLTY
                     ITLAVSAGMIGFGVYLLVLNGPVFLPIVFTFFGFLTLRFAVEDYRKQRRPAQKMHRRVA
                     PWYFQHFTRMGGAYIASFTAALVTNIGRVLPDDAPDWVGTVAWIAPSILGGLIIGRTVR
                     YYLTKFKLTR"
     gene            complement(13334..13975)
                     /locus_tag="AWR27_RS24700"
                     /old_locus_tag="AWR27_24475"
     CDS             complement(13334..13975)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020607083.1"
                     /locus_tag="AWR27_RS24700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24475"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_077134192.1"
                     /transl_table=11
                     /translation="MLANPGSDGSDYLALGDSYTIGEGALEVERWPVQLAGLLRDSGTA
                     ISNPDIIAHTGWTTAELQEAIEKSGNQKTYELVSLLIGVNNQYRGQSRARYRAEFRALL
                     QTAIQFAGGRASRVFVLSIPDWGVSPFASDRDRAKIAQEIDQFNAIAQEECRRAAVAFV
                     DITPTTRRAASEPTPGVDSQFTSDGLHYSGKQMRQWAELALPVVSRLLVS"
     misc_feature    13993..14006
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.38"
                     /tool="antismash"
     gene            complement(14097..15174)
                     /gene="prfB"
                     /locus_tag="AWR27_RS24705"
                     /old_locus_tag="AWR27_24480"
     CDS             complement(join(14097..15113,15115..15174))
                     /codon_start=1
                     /gene="prfB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012930208.1"
                     /locus_tag="AWR27_RS24705"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="AWR27_24480"
                     /product="peptide chain release factor 2"
                     /protein_id="WP_157579301.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MTTDQLTDLRARIEALGRYLDYDTKKEQLAELEQQTFQPEFWTDA
                     ARAEGVMKQVRVLKGWTTGYDKLNSQFGDLETLFEFYEAGEVTEEEVDAEGRKVAETLD
                     DLELKKMLGNEEDQLSAVLEINAGAGGTESQDWADMLYRMYMRWAEKHGYSLKQVDYQE
                     GDTAGIKSATIEVDGPLAYGFLKSENGVHRLVRVSPFDSNARRHTSFASVFAYPLVDDT
                     INIEVNLADIDWDTFRSGGAGGQNVNKVETAVRLRHRPSGLIIECQQERSQLQNKEVAM
                     RLLKSKLYEIEVQKRNAARAEVEAGKQKIEWGSQIRSYVLDDRRVKDHRTGHQTSNTDA
                     VLDGDLDPFIKAFLLNQD"
     gene            15465..16865
                     /gene="lpdA"
                     /locus_tag="AWR27_RS24710"
                     /old_locus_tag="AWR27_24485"
     CDS             15465..16865
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012930209.1"
                     /locus_tag="AWR27_RS24710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24485"
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_077133648.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.6e-67, bitscore:
                     226.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASQYDVIVVGSGPGGYVAAIRASQLGMKTAVIERESLGGICLNW
                     GCIPTKALLKSAQVFEYIKHAGDYGITVQGESQADFGAVIKRSRGVADSMSKGVQFLMK
                     KNKIDVLNGVGKVKTGKKVEVTGPDGKATDYEAKHIIIATGGRARQLPAVPIDGEKVIE
                     YRKAMTLEKRPDSMVIIGSGAIGVEFAYVYASMGTKVTIIEFLPNIVPVEDEDISKELA
                     KQYKKMGVQLFTNSEVTKVDTSGKGCVVTAKTPDGEKTFEADVVLSAAGVVANIENIGL
                     EDVGINTDRGKIVTDDYYRTNVEGYYAIGDCTKGQALAHVASAEAIICVEKIAGLPHVE
                     PLNYNNIPGCTYCTPEIASVGYTEKAAREAGYDLKVGKFPFTASGKAKAAGAPEGFVKV
                     IFDAKYGEFLGAHFIGANVTEMIAEVVAARRLETTGEEILKAVHPHPTMSEAIKDATEA
                     AYGEAIHL"
     gene            complement(16971..18713)
                     /locus_tag="AWR27_RS24715"
                     /old_locus_tag="AWR27_24490"
     CDS             complement(16971..18713)
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1154: Pseudouridine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020599836.1"
                     /locus_tag="AWR27_RS24715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_24490"
                     /product="pseudouridine synthase"
                     /protein_id="WP_077133649.1"
                     /transl_table=11
                     /translation="MNQDFDKNDRQRDDAPRRNERSSGRRDDDRTGNSRPRLARDSDRN
                     DRPRRNNDDKPRFSRDTNRPDERPRFERSNDRRDDKPRFNRDDKPRFGRDNDRQTNAPN
                     RFNRDNDTNKPRFRRDERSEQPRPDRSSRDDKPRFNRDDKPRFSRDERPSRDDKPRFER
                     SDNRPRFNRDDRPRQADNNRDEKPRFNRDSERTERPRFSRDNDRTDKPRFNRDDKPRFD
                     RGGRDENPRFKRVGGFNREADERNRFESQNERRSEPRRNDDRTTTNRNDDESSRFTPAQ
                     RRASGDRRVGDYDKVPNYELAQRRHEQYGQDDRRGKKTSDKYRDKRDAKAAQPTDQPVR
                     TAAQDGLIRLNRYIANSGVCSRREAEELILRGDITVNGKVITELGFKVKDGDTVKYGTK
                     LLSQQRFVYVLLNKPKDYITTTDDPEDRRTVMELVADVGSYRIYPVGRLDRNTTGLLLL
                     TNDGELADKLTHPSNEVKKIYQIEIDKSLTEEHFEAIRKGIELEDGPIKPDALSIVTPD
                     AHVIGIEIHSGRNRIVRRIFEHFGYEVTRLDRTMFAGLTKKELPRGKWRFLDPKEVVKL
                     KYLS"
     misc_feature    18854..18867
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.19"
                     /tool="antismash"
     misc_feature    19268..19281
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.67"
                     /tool="antismash"
     misc_feature    20626..20641
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.2"
                     /tool="antismash"
     misc_feature    20910..20923
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.36"
                     /tool="antismash"
ORIGIN
        1 cgtagccttc aatgacggta ggtttggtct gttccgccaa ttcgattcgc gaacctgtct
       61 ggcttttggc agagtggtag ggcttaaacg gaagttcttc ctgcgtaacc atttccgtaa
      121 actcaacccg ctgttcgagc gacagatcgg tccattcgtc tttcaggaat gtgttgtacc
      181 agcggccatg ccagttaaat acgcccccta cgcctacttc attccgggcc gcttcgaaag
      241 cctcatcgaa cgacatggcg tcggtagttt tgccagccac gtcgatatcg gcgggtaatg
      301 caccaacagg tgttgtgggc gtggctaagt ccatgccggg ctgaccttca ggtgatgagc
      361 ctgacttagg aatttttgag gcaacggccc aggcggctcc accgagcagg agggtagccg
      421 ccgagatgcc cagcattttt ttctgatcgg cagagaggcc atttgtcgta gacatggttg
      481 agcggtttgg cgtaaacgta tcggtttgca taaattgaaa aatgagaagg ttgaaacagg
      541 gtgtggatag ttttcttttt cgtgtggatc attcctttat cgggcgagtt tgaaaaaggt
      601 aagtgatcga cgcgaaaaaa atttagctta cccaaatggc ctggcatcgg cggcagcttt
      661 tttgctgagc caggaggtcc cattcgcggg tgccgaacgg atcgcggcag gtagggttgg
      721 ggcagcggta gcgttcgcga tattgtttgt cgattaattc taacttctct tcggtcgaca
      781 gcagcgtcga gcacaacgta ggtacgagca tacttagccc ggctcccgac ataatctgta
      841 gaatcggtat cgacccgccc cctgtggcta tggccgcgct cacgcccacg atagacgaca
      901 caatcacgct gcccgtgcgg atcatctttt cacggttgcg gcagtcgcgc cgaagtttcg
      961 gatattgctc gtaaactgtc tgtaaatcag aaaactggcg cgaaaagtcg agcgaatcag
     1021 cggcttctgg tgctggtttg gatgcagtag gctgcggcag aacgggctgc tctggcgtat
     1081 tggcgggtgg cacaacccgg agggcgagca actgattagt agtataatcg acgtcggcca
     1141 ggcggatagt gtcgccgtct gtaatcagtt tacgcttgat gcgctgctga ttcacaaacg
     1201 tgccattttt gctgtcgagg tcttcgagta cgaaatcggt gggtgtacac tgaatcagcg
     1261 acgcgtgttt gctgctgatt ttcgggttgg ctaccacgat gtcgttatcg gcaccgcgcc
     1321 cgatggtaaa caccggcagt tggctcaact gctcaagctg ctgttcaaac caaatagccg
     1381 gttttgttaa cgttgagaag gtcatacaaa ggcaatctaa cgcagcaagt tacatctggt
     1441 aagtacatta ggaaataggt tggttcactt attttgtaaa cggtaggtat cgcttattat
     1501 acggtatgaa cccttatctt cgcctatcga atttataccc ctatgtttat cggcatcatt
     1561 ccggcacgct acggttcgtc gcggtttccg ggtaaacccc tcgctcaact caacggcaaa
     1621 cccatgattc agcacgtttg ggagcgcacc tcacaagcca gatcgctcga ccgcgtggcg
     1681 attgctaccg acgacgagcg cattgccagc gtagcccgcg cttttggggc cgacgtactc
     1741 atgacccgcc ccgaccacgt gagcggcacc gaccgctgct acgaagccta caacctgctc
     1801 cgcccgcaac tgccgcccca aagcgatgcc cagcattatg tagtgaatat tcagggcgac
     1861 gaacccttta ttcatcccaa tcagatcgac gggctgactg ttattctcga tggtgcggta
     1921 gaaattgcca ctcagtgtgc caaaatcgat tcggctacca ttctgcacga cacgggagaa
     1981 gtaaaaatcg cgctcaccaa acagggcgac gcgctgtatt tcagccgcca gccgattccg
     2041 tttctgcggg gcgtcgaccc ggcggagtgg cacacgcgct acccttatta ccagcacgtg
     2101 ggtttgtatg cctaccgcgc cgatattctg gagcagatca gccaactgcc gccctcaccg
     2161 ctggaacagg ccgaatcgct ggagcaactg cgctggttag aagcgggtta taaagtaaag
     2221 cttgtcgaaa ccccctacgt cagcatctgc gtcgatacgc ccgccgactt agaaaaaatc
     2281 agccggattc aggggggcgt ttgacggcga atcaggcgac tgcgtatcct gtgtagggac
     2341 gtttgtatgg agcgtgaaat gccagcacaa tatcatcttt actgactccc ctacgttcga
     2401 gttcaccaac aatatcaaaa tcggtagcat cctcctgcac ccagattttg ccgtttttaa
     2461 tatcgaggtg gaagaccggg taatacacac gtttaccgtt ttcccagcca atggtcagaa
     2521 tctggtaatg gtcgcgctcg gcgtctataa tgagttgttc ttcaacttga tcgtcaccta
     2581 tgaaaatagc aggtgcattg gcatactgcg tcagcaattc ggtaattaac gttcgatatg
     2641 tatttacctt gctatccatt gtacaattcg cttagagtta gcatcaaaaa ctaacagtga
     2701 aatgctataa tcagcaacga tcttttgaat caaaggtttc tggaagaatg aggtatatat
     2761 atctgtatcg acggccagaa aaagttttcg agatggtcta tcctcttgaa ggccaattaa
     2821 ataaacatca tattgacctt tggcttgata aaaatcgctg agtttcgact tactcaaaaa
     2881 gctttttact tcaaccgcaa tatgttcaga acctcgttca gccgccagaa cctgttcggc
     2941 tgccaaatct atttcgagtc gcaaaccacc gagttttaaa atcagcgggt catgagtaat
     3001 tagccatcca tcggcttcaa gggcttcacg aactacttga tgaaatatgt cacgcgccat
     3061 aaagtaaaag tacaggcttc actcggtttg gcaaaacatt aataaagtag atggccatca
     3121 ctccaattat tggtaatcgg aatttaaccg gatttccgtt gcattccccc cccgtacccc
     3181 ctacctttgc gggatttttg gccttacgat atccccatcc gacggccagt attgtacatt
     3241 gtttattgcc ccttgtacat tccctccaaa gatgcccaaa aattctgcca tccgctcggt
     3301 tctgattatt ggctccggcc ccattgttat cggtcaggcg tgtgagttcg actacgccgg
     3361 ttcgcaggct gcccgctcca tccgcgacga aggtatcgag gtcagtctga tcaactccaa
     3421 tccggctacg atcatgaccg acccgatcaa tgccgaccac gtgtatctgc tgccgctcga
     3481 aaagaagtct atcgtcgaaa tcctgaaaaa acatcaggac atgggcaggc ccatcgacgc
     3541 ggtgctgccc acaatgggcg ggcaaacggc cctcaacctc gccatcgact gcgagaaggc
     3601 gggtatctgg cagaaatacg gcgtcaaaat tatcggcgtc gacatcaaag ccatcgaaac
     3661 taccgaagac cgcgaaaaat tccggctgct gatgcttcag ttaggtgccg gggtttgtaa
     3721 aggacgcacg gcccggtcgt ttctggaagg gaaagaaatt gcccaggaaa tcgggtttcc
     3781 gctggttatc agaccgtcgt ttacgctcgg cggtacgggg ggcggcttcg tgaatacgcc
     3841 cgaagagttc gataaagccc tgacacacgg cctgcacgca tcgcccgtac acgaggtgct
     3901 ggtagaacag agcgtgatgg gctggaaaga atacgagctt gaactcctgc gcgataataa
     3961 cgggaacttc attatcatct gctccatcga gaacttcgac ccgatgggca tacacaccgg
     4021 cgacagcatt acggtggccc cggccatgac cctgcccgac acgctgtacc agcaaatgcg
     4081 cgacctcgcc attcgggtta tgggcggcat tgggcagttt gcgggtgggt gcaacatcca
     4141 gttctcggtg aacccgcaaa ccgacgacat cattgttatt gaggtgaatc cgcgcgtaag
     4201 ccggtcgtcg gcactggcat cgaaagcaac gggctatccc atcgccaaga ttgccgccaa
     4261 aatggctgtt ggctacaatt tggacgaact tatcaacccg attacgggca cgacttcggc
     4321 cttttttgaa cccgccatcg actacgtaat tgtaaaggtt ccgcgctgga acttcgacaa
     4381 atttccggga gccgaccgtt cgctgggcct gcaaatgaag tcggtgggcg aggcaatggg
     4441 cattggccgc aacttccagg aagctttgca aaaagcctgt cagagtctgg aaatccggcg
     4501 caatggcctc ggtgccgacg ggcgtgaatt gaacgaccgc gaagcactga ccaaaagcct
     4561 ggcacaccca agctggaacc ggctgttcca catctacgat gcttttaaag ccggaatgtc
     4621 gttccgcacg attcagcaac tgaccaaaat agacccctgg tttttgcatc agatcgaaga
     4681 actgattctg ctcgaacgcg aaattcagca gtacgatctg gacgatctgc cgcccgaact
     4741 gctccgcacg gccaagcaaa aaggctatgc cgaccggcaa ctggcgcacc tgttgcaggt
     4801 gaaagaaagt aagatttatc agtaccggca gcagcacaac atccggcggg tgtttaaatg
     4861 cgtggatacc tgtgcggctg agttcgaggc caaaacgccg tattactact cgacgttcaa
     4921 caatcagttg cccatcaccc aggaccggcc cgaacccgta tccgacctgc ccggcaacga
     4981 atcgatccgc tcgaaccgca agaaagtggt ggtgctgggt tctggcccga accgcatcgg
     5041 gcagggtatc gagttcgatt attcgtgcgt tcacggggtg ttggccgcca aagaagctgg
     5101 ttatgagacc atcatgatca actgcaaccc cgaaaccgtt tcgaccgacc cagatattgc
     5161 cgacaagctg tatttcgagc cggtgttctg ggaacacgtt cacgccatta tcatgcacga
     5221 gcaaccggag ggcgtaattg tgcagttggg cgggcaaacg gcactgaaaa tggccgagaa
     5281 actgacccgt tacggtatca aaatcattgg cacaagctgg gaagcactcg acttggctga
     5341 agaccggggc cacttctccg acatgcttcg caagctcgac attccgtatc cgaagttcgg
     5401 gacggtgcgc gaagccgaag ccgccatcga actctcacgc gagctgggtt tcccgctgct
     5461 ggtacggccc agctatgtat tgggcgggca gtcgatgaag attgtgatta atgaagagga
     5521 attggaaagc cacgtgatga agattttgca ggatattccc gacaacaaca tcctgctcga
     5581 tcacttcctc gaaaacgcca tcgaagccga agccgacgcc atctgcgacg gagaagacgt
     5641 gtatatcatc ggtatcatgg aacacatcga accggcgggc atccactccg gcgattccta
     5701 cgccgtgttg ccgccctttg acctgagcga gaacgtgatt cggcaaattg aggaatatac
     5761 aacgaaaatt gccgtggcgt tggagactaa agggctgatt aacatccagt tcgccatcaa
     5821 aaacgaacag gtgtacgtga ttgaagccaa cccccgcgcc agccgcacag tgccgttcat
     5881 ctgcaaagct taccaggaac cttacgtgaa ctacgccaca aaggtgatgc tgggcgacaa
     5941 gaaggtaaaa gatttcgatt tcaagcccgt aaagaagggt tacgccatca agattccggt
     6001 attctcgttc aacaaattcc cgaacgtaaa caaggaactc ggccccgaaa tgaaatcaac
     6061 tggcgaaggc atctatttca tcgacgattt gcaggacgat ttcttccaaa aggtgtactc
     6121 ggagcggaat ttgtatctga gccggtaaaa actaaagggg aacacggatt gaacggatgg
     6181 ggcggattga cacagatttt taacataaag aaatctgtgt caatccgccc catccgttca
     6241 atccgtgttc ccctttactc cttaaaaacc taaccccagc gcgaagccgc gaaccgttgg
     6301 gttgccgggt agcgcaatgc cgttagaagc ctgacccgtg gttaagttga tgctgtagat
     6361 acgggttgtg ccgcccgaac ggagcagggc atacgccgaa ttgctcgtac cgccaatatc
     6421 gaagccgtta ccaccttcaa tgggtatgcc caatgaccca acggctacta atccaccagc
     6481 gttcggcggg tcctgacgca tcagcattgc attctcggtg cgggtgtcaa tgtcgaagag
     6541 caccgtgctg gtagtaccgg caaagttgtt ggtgtaggct gccgccgtta cattgggcga
     6601 acccggattc agattaccat caaccgctgt aacagtgccg tcattggggt taagccgcag
     6661 attctgaccc gaattagtca ctaaccgaat acggtcgacc atcggattga agtcaaagcc
     6721 acggtcattg cccgatagtg acgctgcaaa tggtcctgac ccaacaggag cagccgcgcc
     6781 attcgacgta ttaatcgtgt acaggcggtt ggtgctaccc aatgcataca attgaccgtt
     6841 ggccgggcgg aaatcgatgc cgaaaatcgt ttcgccgttt tgcagacccg taatggtttt
     6901 gctgattggg ttcgggttga gcggattaaa aatgagcaga ttattcaatc catcgacggt
     6961 ataagccacc ggctcggttg gaatggcgat accaataagg ctcaggttcg gcagatcgct
     7021 cagccgctcg gcgcggccac tcatcaggtc aatttggtaa aaaccctgcg tagtgccgct
     7081 aatcaggatt gccactgcac tgccatcggg ggcgatgtcg aagctgcccc gcccggcgat
     7141 gtcaatgccg agcgaaccaa cttcggccag cccacccgcg ttcggcggat cctgacgata
     7201 caatttgtcg gtaagcgggt caatgtcgta cagtatggtg ctggtgacgc ccgcccggtt
     7261 gttggtgtac gctactccgt tgatggcaac cggagccggg ccgttgatgg aaccgtcaac
     7321 aaccatcaca gtgccggttt cggggttcag tcgcaggttc tgcccccggt tggttactaa
     7381 ccgaaggcgg tcgacggtag gattgaaatc aatcgaaacc acgtcgccgg caacgggcgg
     7441 cataaacggc cccatgccta ccatccgggc cgcgcctgtg ttggggttga tggtgtatag
     7501 ccgactgcca tcgctaacgc cgtacagttg ccccgttgcc gggcggaagt ctatcgattg
     7561 caaccgctca ccactcgcca gtccggtaat tgtggtggta gccagtgcgg aagttggatt
     7621 ctgcgagttt aacagcaaca actgattgtt gtcggttagg gcgtagaagg tgaaattggc
     7681 cgacagccgc gcctgggccg cacctaattc ggcccgcgag tcaataagct gctcttcctt
     7741 acaggcattg agcatgagca gtgagccgat agcgagcaag gcagctacag ggcgtaggtt
     7801 tttcagaaca cgcatagtcg tagttttctg gttgaaacgt tttgcatcgg taaatcagaa
     7861 atttagaaac acctgactat acgtatgttt gtagcatctg gatgttggcc tgcacaaaaa
     7921 gccagataaa ttgttagtat cttatcgtat ggagaaactc gaagacgccc ctaaattcaa
     7981 gttctggaaa agtcagattg aagctaacgg attgacaata aatggtataa aagatcattt
     8041 tatcaggcgt cggcacaacg gcgaggtact gtttgccatg cttgagttag atgccgacac
     8101 gcccgaaggc gataaaattc cgcccgtctg ttttcttaaa ggccatgctg cttcggtatt
     8161 agtgtgcctg attgatgacc aaacgggcga aaaatttgtc gtattggtca agcaacggcg
     8221 catatccgac ggttcgcaaa cctacgaaca ccccgccggt atggtcgatg ccgccgatga
     8281 ccccgccgat gttgccgccc gcgaattagg cgaagaaatc ggtctggaag ctaccgccac
     8341 tgaactgacc aagttgaacc cccggctgtg gttccccagc accggcacga gcgacgaagc
     8401 gatgcacttc ttcttcatcg aacgcacgat gccccgcgcc gaaatcatgg catttcacca
     8461 caaaaatatg ggtaaccatt ctgaatttga gcgaattaca acggcagtag caacgcttcc
     8521 cgaagcccat aaattagtta acaacgtaaa cggactgctt attcactttc tttatctgaa
     8581 gcacgttggt gattacgaaa ccatgaagcg gctttaaaac tatggacgaa tttatgcagg
     8641 aggccattcg gcaggcgcgg aaaagcttag acgaaggcgg tattcccatc ggctcggcac
     8701 tggtaaaaaa tggcgcattg atggcgtcgg gccataacaa acgggtgcag gaagataacc
     8761 cgattctgca cggcgaaatg gactgcctca acaacgccgg gcgtgttggg tcgtttcgcg
     8821 acacggttat ttactctacc ctgatgccgt gctacatgtg tgccggaacc atcgtacagt
     8881 tcaaaattcc gaaagttatc gtcggtgaat cgcggacatt tgccggtgcc cgcgagttta
     8941 tggaacagca tggcgtcgaa gtggttgacc tcgatttgcc cgaatgcgtt gccatgatgg
     9001 agcagttcat cgccgaaaaa ccaaccctct ggaatgaaga cattggcgaa ttgtaattgg
     9061 cgtaattcat agcatggtta ctaaatggta ggtggttcgt cttataggcg aacgtcctgt
     9121 catcatgaaa acccgccacc gtttttgtct gctaattgtc ctgcttataa accacataag
     9181 cacatttgcc caacggtcgg cctactggca cgagaagccc ggaacgtggc tgctgaatgt
     9241 tggcacagga gctacccgat atgctggcga tctggccgaa gccggtaatc tggcgcatct
     9301 gcaactgggc gcggctctgg gtgtggccgg aacgtaccgc gccacgcaac ggctctcgtg
     9361 gcgggccgaa gcgcaactgt actacgttta cggctggcag aaatacaccc gaaattatta
     9421 taacaacctc tcgttcaata gcctgaatcc cgatgtttgg gcggggattc agttcgattt
     9481 ctggcctgta aacgaccccc accgggctac tatcccgtat gctatggcag gtgtgggact
     9541 tacccatata acgcctaaag cccgttatga aggccagaac tatagtttac ctcaatttga
     9601 aacagaaggc gttgcctaca accggctgcc acttattatt cgctacgggg ttggtttgcc
     9661 aatgctgtcg accgaacggc taaggtttca tcttgaaggc acctatacgc acgttttgag
     9721 cgactatttc gacgacgtta gctcgatata catcgaccga agtaacatga ccccgctcgg
     9781 tgcagccttg accgaccgac gcgccgaact tggtacaacg ctcaaccgac ccggcgaaca
     9841 gcggggcaat acgggtaaaa atgacggtta ctttgtgttg agtggtcggt tggttgttgt
     9901 catcattacg ccacagcaac gcaattaccg gcgcatgttc gggcgttagg gttttggggg
     9961 cttttgccgt atttttggcc ccaaacccac tcgactacta atgaatccag ccgtttttat
    10021 tgaggccatt caagcagaac ttcaacgcac taaatacggg cagtaccctc ccgaactgta
    10081 tgaccccatt cggtatatca tgagcctcgg cggcaaacga atgcgtccgc tgctgaccct
    10141 catggcaacc tatcttttca ccgacgactg gaaacaggcc attcggcccg cgctgggtgt
    10201 ggaggtcttt cacaatttca cgctcatgca cgacgacatc atggaccagg ctccactgcg
    10261 tcgggggcaa ccaaccgtgc atgaacgctg gaacgccaat attgccattc tatcgggcga
    10321 tgtgatgctg gtgaacgctt acgaactgct gctcgacgtg gctcccgaca agctcaaagc
    10381 cgtgatgagt cgctttaacc gtacagccgc cgaggtctgc gaaggacaac agatggatat
    10441 gaatttcgag acgcggtggg acgtgaccga agccgaatac atcgacatga tccggctgaa
    10501 aacgtcggtg ttgcttggct acgcgctcga actcggtggc ctgattgccg gtgccgacgc
    10561 cgaaactaac cggcatctgt acgaaggggg cgtaaacatt ggcattggct ttcagttgaa
    10621 agatgacctg ctcgacgtgt acggcgaccc ggccaaattc ggcaaacaag tggggggcga
    10681 tattctggcg aataaaaaaa cctttctgct catcgaagcc ctcgaaaaag ctaccggccc
    10741 gctcaacgat gaactgaacg gctggcttac caaaactgag ttcgacaaag ccgaaaaagt
    10801 acaggccgta acggccattt atgaccagtt aggtattcgg cagattaccg aacagcgtat
    10861 caatgcatat tttgcacgcg gctttgccaa cttcgaccaa cttaaggccg accccacccg
    10921 ccgactcctg cttacccaat tcgctcgtca gttagtcgag cgtgaaagct aaacatcaca
    10981 tgaacattac ccttgttatt atactcgtta ccgttggcgt gagcctggca gcctggaaca
    11041 atccggctct gatgagtcgc tggattatga atccctatca ggtcatgaac cgggggcaat
    11101 attaccggct gctgacatcc gggtttctgc acgccgactg gggccacctg ctgttcaaca
    11161 tgctgagtct gtattttttc ggcggtttta tcgagcaggt ttttgcctac ctgtttggtg
    11221 gcaacggcgg gctgtatctg attggctttt atttagtcgg aattgttgtg tctgatattc
    11281 caacgttgct gaagcaccgg aacaacccca gctataactc actgggcgcg tcggggggcg
    11341 tatcggccat tttgtttgcg gctatcctgt tccggcccct aacgccgatc tacttgttct
    11401 tcattccgat tggcattccc ggctttattt tcggagcgtt atatctggca tattcctact
    11461 acgaagcccg gcgtggctac ggcaacgtga atcacgacgc gcacttttac ggagctgtgt
    11521 tcggtgtgtt gtttatgatt gtggtatacc ccgaagtagt gccgcagttc ttcgatcagg
    11581 tgtcgggctg gcggcttttc taaaccatgt ttaagttact cgcacagccg tacccaaccg
    11641 aagaatcgct acgacgccga ttgctgaaat catttactat tggggcgttt gtgggcctgt
    11701 tcttgttgct ttttcagccg tttggtatcg atgactggca aaccgatgcc aaagtctgga
    11761 aagtgctggg ttttggagcc gtaacgttgg cggtgttgct gctgaactgg tttgcgctgc
    11821 ctgcgttgtt tccccggttc ttctcagatg ctcaatggac cgttggccgc gaaattgtgc
    11881 gggtattgtc gttcattctg gcgattgcga ttggtaacgg gctatacatg aactggctgt
    11941 tcaaccggca tcctacaatt gggagctggc tttggataat tggcgttaca tttctgattg
    12001 gcatcttccc cacggttggg tctatcatgc tcaactacat tattcaattg cgtcgctaca
    12061 gccgctcagc cgccacgctt aacccagttg cacacaacac cgccgaatca acactccaaa
    12121 ccgaaacggc atcgcccccg cccctgagcg atacgctgac attattggct gacaatgaaa
    12181 aagatacgct gacgctcgaa ccggctaagt tgctctttat cgaatcaagc gataattact
    12241 gcacggtcgt ttatctgaaa aacgacaagc ccgccaaggt tctgctacga agcagcctga
    12301 gccgcatggc cgaccaaatt cagcgacccc acattgttcg ctgccaccgg tcttatatcg
    12361 ttaacctcga ccgggtagag cgcgtgacgg gcaacgcgca gggctacaaa ctacacctcc
    12421 tcgacgggca gtttgccttg cctgtttcgc gtcagtacaa cgatacgctc gtagccgaac
    12481 tgaaggcgtt gtaattcacc tttgtcattc gtcccaaccc acgttcttct ttgccaaatg
    12541 ccccaaacgg tgccgtttgg ccctattttt tgttcggagt ttctgagccg ctgtacgttt
    12601 gcatcatcaa ccgcaaccaa caaaacggct atgaacacgc tgctcactat tctcctcatc
    12661 acccatattg ctactggctt tacggccctg ctggtgggac tgattccaat gtttgctacg
    12721 aaaggcagcc aactgcacaa ccgagccggg ctggtctttg tctattgtat gattgccgtg
    12781 actctcacgg ccttgctgtt gtgtgtgttg cagccgttta agatgatgcg gctatttctg
    12841 acaggcattg ctgtattcag tttctacctg agcatgaccg gctggcgggc caccaaacaa
    12901 aaaaacgggc aggtggctgc tttcgaccac tggctgacat acataacgct cgctgtcagc
    12961 gcgggtatga ttggttttgg cgtgtatcta ctggtattga atgggcctgt ttttctgccg
    13021 attgtcttta cattcttcgg ttttcttacc ctccgattcg ccgttgaaga ttatcgtaaa
    13081 caacgcagac ccgctcagaa aatgcatcgg agggtcgcac cctggtattt tcagcatttc
    13141 actcgaatgg gaggggcata tattgcttcg tttacggcgg cattggtcac caacattggc
    13201 cgcgtgttgc ccgatgatgc ccccgattgg gtaggtacgg tggcctggat tgcgccgagt
    13261 atacttggcg gactaattat tggccgaacg gtgcgctatt acctgacgaa gttcaagctg
    13321 acccggtaat cgactacgaa accagtagcc gactgactac tggcaacgcc agttcggccc
    13381 actgtcgcat ctgtttacca gagtaatgca gaccatcgct ggtaaactgc gagtctacgc
    13441 ccggcgtggg ctcacttgct gcccggcgcg tggtgggcgt aatgtccacg aaggctacag
    13501 cggcccggcg gcattcttcc tgcgcgatgg cattgaactg gtcaatctcc tgcgcgattt
    13561 tggcccggtc gcggtcgctg gcaaaaggtg aaacgcccca gtcgggaatc gatagcacga
    13621 acacacgact ggcccgcccc cccgcaaact gaatagccgt ttgcagcaac gcccgaaact
    13681 cggcacggta acgcgcccgc gactggcccc ggtactgatt gttaacgcca atcagcagcg
    13741 atactaattc ataggttttc tgattaccgc ttttctcgat ggcttcctgc aattcagccg
    13801 tagtccagcc agtatgggca atgatgtcgg ggttggagat ggccgtgcca ctgtcgcgca
    13861 acagcccggc caactgaacc ggccaccgct caacctctaa cgcaccctcg ccaatggtgt
    13921 acgaatcgcc gagcgcgagg tagtcagaac catctgaacc aggattagcc aagattttcg
    13981 ggattaaaca agattctaaa ctaaaaccgc taacattcaa aagtgtcagg aataaaacaa
    14041 gattcaacag tttacaagcg aagcgcataa atcttgttta atcccgaaaa tcctggctaa
    14101 tcctggttca gaagaaacgc cttaataaac gggtctaaat cgccatcgag tacggcatcg
    14161 gtgttggaag tttggtggcc ggtgcggtgg tctttcacgc gccggtcgtc gagcacatag
    14221 ctgcgaatct gcgaacccca ctcaattttc tgcttcccgg cttctacttc ggcacgggct
    14281 gcgttgcgtt tctgcacttc gatttcgtag agtttcgatt tcaacagccg catcgccacc
    14341 tctttattct gcaattgcga acgttcctgc tggcactcga ttatcagccc cgaaggccgg
    14401 tgccgcaacc gaactgccgt ttccacctta ttgacgttct gcccaccggc cccgcccgac
    14461 cggaacgtat cccagtcaat atcagccaga ttaacctcaa tgttaatggt atcatcaacg
    14521 agcgggtagg caaacaccga cgcaaaggac gtgtgccgcc gggcgttgga atcgaacggc
    14581 gatacgcgca caagccggtg aacgccattt tccgatttca gaaacccata tgccagcggc
    14641 ccatcgacct caattgtggc tgatttgatg cctgccgtgt cgccttcctg ataatcgacc
    14701 tgtttgaggc tataaccgtg tttttcggcc cagcgcatgt acatccggta gagcatgtcg
    14761 gcccagtcct ggctttcggt gccgcccgct ccggcgttga tttcgagtac tgcgctcaac
    14821 tggtcttctt cgttgccgag catttttttg agttcaagat cgtcgagcgt ttcggctacc
    14881 ttgcggcctt cggcgtctac ttcttcttcg gttacttccc cggcttcgta aaactcaaac
    14941 agcgtttcga ggtcaccaaa ctgactgttc agtttatcgt atcccgttgt ccagcctttt
    15001 agcacacgaa cctgtttcat cacgccctcg gcgcgggcgg catcggtcca gaattcgggc
    15061 tggaacgtct gctgttcgag ttcagctaat tgctcttttt tagtatcgta gtcaaagata
    15121 cctccccaga gcctctattc tggccctcaa gtcggtcaac tggtcagttg tcatgaactt
    15181 gtcttgtgtt agttagaaag ttgtgataca gagatgcacg aaggaagcac agagatacgc
    15241 agagaaattt aaaaactttg tgtatctccg tgtcttctcc gtgtatctct gtgtcacaac
    15301 cacaaagata gaacaaaagc agcggggggc gttgtttcgg ggaagcccgc aaaccaactt
    15361 ttcgctatac ctttgcgttc tcaaaatagc atacgtgacc gctgcgaaca ggtttacgca
    15421 gcacacactt ttcagtatac attcttcatt tttcacttat aaaaatggct tcacagtacg
    15481 atgttatcgt ggtaggtagc ggaccgggcg gatacgttgc cgccattcgg gcttcgcagt
    15541 tgggtatgaa aaccgccgtg atcgagcgcg aaagtctcgg cggcatttgc ctcaactggg
    15601 gctgtattcc aaccaaagcc ctgttgaaat cagcgcaggt ttttgaatat atcaaacacg
    15661 ccggcgacta cggcatcacg gtacagggcg aatcgcaggc cgattttggg gccgttatca
    15721 aacggagtcg gggtgtagcc gatagcatga gcaagggtgt acagttcctg atgaagaaaa
    15781 ataaaatcga cgttctcaac ggcgtcggta aagtgaaaac cggcaaaaaa gttgaagtaa
    15841 ccggtcccga cggtaaagcc accgactacg aagccaagca cattatcatt gccaccggag
    15901 gccgcgcccg ccaactgcct gccgtaccca tcgacggcga aaaagtgatt gagtaccgta
    15961 aggccatgac gctcgaaaaa agacccgatt cgatggttat tatcggttcg ggagccattg
    16021 gcgtcgagtt tgcttacgtg tatgccagca tgggtacgaa ggtgacaatc attgaattcc
    16081 tgcccaacat tgtgccggtt gaagacgaag acatctcgaa agaactggcg aagcagtaca
    16141 agaaaatggg cgttcagctt ttcaccaatt cggaagtcac aaaagtagat acgagcggca
    16201 aaggctgcgt tgtaacggcc aaaacccccg atggtgagaa gacgtttgaa gccgatgtcg
    16261 tgttgtcggc agcgggcgtg gttgccaaca tcgaaaatat tggcctggaa gatgtcggca
    16321 ttaataccga ccggggcaaa atcgtaaccg acgattacta ccgcacaaac gtagaaggtt
    16381 actacgctat cggcgactgc accaaagggc aggcactggc gcacgtagcg tcggcagaag
    16441 ccattatctg tgtcgaaaaa attgccggat tgccgcacgt tgagccgttg aactacaaca
    16501 atattccggg ttgcacgtac tgtacacccg aaattgcgtc ggtaggttat accgaaaaag
    16561 cggcccgcga agccggttac gatctgaaag tagggaagtt tccgttcacc gcgtcaggta
    16621 aggccaaagc tgctggcgca cccgaagggt ttgtaaaggt aattttcgac gccaaatacg
    16681 gtgagttctt aggtgctcac ttcatcggcg cgaacgtgac ggagatgatt gccgaggtgg
    16741 tagctgcccg tcggttagaa accacgggag aggaaatttt gaaagccgtt catccgcacc
    16801 ccaccatgtc ggaagccatt aaagacgcta ccgaagcagc atacggcgag gctattcacc
    16861 tgtaaggttt agtctaaacg cagagtggcg gaggttgcac agagtacaca gagcttaaat
    16921 caaacacgct gtgtactctg cgcaacctcc gccactctgc gtttgaactc ttaactcagg
    16981 tacttcagtt tcactacttc tttcgggtct aagaaccgcc atttgccgcg cggcagctct
    17041 ttcttcgtca gtccggcaaa catagtgcgg tcgagccggg taacttcata tccgaaatgc
    17101 tcgaatatcc ggcgcacaat gcggttgcga cccgaatgaa tttcaatgcc aattacgtgt
    17161 gcgtcgggtg ttacaatgct aagcgcgtcg ggcttgatgg ggccatcttc gagttcgatg
    17221 cccttgcgga tggcttcaaa atgctcttcc gtcagtgact tatcgatttc tatctgataa
    17281 atcttcttca cctcatttga tgggtgcgtc agtttgtcgg ccagttcacc atcattggta
    17341 agcagcagca gacccgtggt gttgcggtct aagcggccta cggggtaaat gcgataactc
    17401 cctacgtcag caaccaactc catcaccgtt cggcgatctt cggggtcgtc ggtagtagtg
    17461 atgtaatctt tcggcttatt gagcagtaca tacacaaacc gttgctggct tagcagtttc
    17521 gtgccatatt tcaccgtgtc gccatctttt accttgaagc ccaactcggt tataactttg
    17581 ccattgacgg taatgtcgcc ccggagaata agctcttcgg cttcccgacg cgaacaaacg
    17641 cctgaattag caatatatcg gttcaggcga atcagaccgt cctgcgcggc tgtccgaact
    17701 ggctgatcgg tgggctgtgc cgctttggcg tcgcgtttgt cgcggtattt gtcgctggtt
    17761 tttttaccac ggcggtcgtc ctgaccatat tgctcatgac gacgttgtgc cagttcgtag
    17821 ttgggcactt tatcgtaatc gcccacgcgc cggtcgcccg atgccctgcg ttgagccggt
    17881 gtaaagcgcg acgattcgtc atcgttccga ttggtagttg tgcggtcatc gttccggcgg
    17941 ggctcgctcc gacgttcatt ctggctttca aagcggttgc gctcgtcggc ttcccgatta
    18001 aaaccaccta cccgtttgaa acggggattt tcgtcccgcc cgccccggtc gaaacgaggt
    18061 ttatcgtcgc ggttgaaacg tggtttatca gtacggtcat tgtctcggct gaaccggggt
    18121 cgctctgtac gctctgaatc ccggttgaag cgcggtttct catcgcgatt gttatcggcc
    18181 tgacgtgggc ggtcatcgcg gttaaaacgg ggccgattat cgctccgttc aaaacgcggt
    18241 ttgtcatcgc gtgagggccg ctcgtcccga ctgaaacgcg gtttgtcatc ccgattgaaa
    18301 cgcggcttat cgtcgcggct gctccggtca ggccggggtt gttcgctgcg ttcgtcgcgc
    18361 cggaaacgcg gtttattcgt atcgttatcg cggttgaatc gattcggggc attggtttgc
    18421 cggtcgttgt cgcggccaaa acgtggtttg tcgtcccgat tgaaacgcgg tttatcgtcg
    18481 cgtcggtcgt tgcttcgctc aaaccgtggc cgttcgtccg ggcggttggt atcacggcta
    18541 aaccggggtt tgtcgtcgtt gttccggcgc gggcggtcat tgcggtcact atcgcgcgct
    18601 aagcgggggc ggctgttgcc ggtacggtcg tcatcccgac ggccagaaga acgttcattt
    18661 cgccggggcg catcgtcccg ttggcggtcg ttcttatcaa aatcctgatt catggaataa
    18721 tacagtaaat agtactgtga aggaaagcga acatgctgat tatcagtctc acgactgtta
    18781 tgcaagtcaa aaagggatgc aaagatactg ctttttacag gaaccacacg gtagtggttg
    18841 tgcgcagaac gtaattttta cagaaaacaa tccaggaccg ctgatggtcg ttagcgatat
    18901 agtgccgaag acagtgcttc ggctgtaaaa tagttttcct acctacagcc gaagtactgt
    18961 cttcggtgct atatcctact atgccccacc cgacacgtac acccatttac acccccgacc
    19021 gccgaaccag cgaccagtcg ctcctgaaaa aatacatgga ctggctgttt atcaaaaagg
    19081 gcctgtattt ccgagattat gacgacctct gggattggtc ggttactgac ctcgaagatt
    19141 tttgggagag tatctggcag ttcttcgacg tacagagcca tacgccctac aaccaggtaa
    19201 tttaccgacc taccaatgcc gatatgattg gtactgaatg gtttgtaggg gcaactgtca
    19261 actacgccga acatattttc cggcacaaaa cgtcacagcg gcctgctatc gttttcgcat
    19321 ctgagcggtc ggtggagcgg gggcagcggc tctcggctct gtcgtgggac gaactcgaac
    19381 ggcaggtagt agccgtgtcg acctggctcc ggcagcaggg cgtgggcgtg ggcgaccgtg
    19441 tggtggccgt gttgcccaac attcctgaag ccgttgtggc ttttctggca accaacgcca
    19501 taggagcggt gtggtcgagt tgttcgcccg attttggcac ggccagtgtg gttgatcggt
    19561 ttcagcagat tgaacccaag gtgttgattg ctgccgatgg ctatacctac aacggcaaac
    19621 caattgataa aaccgacgcg atgcgcgaac tgcgccttag cttaccttcg ctgcaacggg
    19681 ttgtgtgggt gccatttctg gatgtagaga accggctcga acgcagcgta ctgtggcacg
    19741 atgtgctgga aacagctgcg cccgacgagc ttgattttga accagtgccc ttcaatcacc
    19801 ccatttgggt gctatactca tcgggtacaa cgggcaaacc gaaagcaatt acgcatagtg
    19861 tgggcggctg tttgctcgaa caccttaaag tgctgaccct gcatcaggac gtgcgcgtgg
    19921 gcgaacgcta tttctggtac tcgaccaccg gctggatgat gtggaatttc gcggtaggtt
    19981 ctatgctcgt tggagccacg ctcgtgctgt atgagggcgc ggctggttat cctgatctaa
    20041 acatactctg gaatctggcc gaggctgggc gggtcaatca ctttggcggt ggtgcggcct
    20101 actatttagc ctgtttgcgg gcgggcattt caccgcgcaa cacgttatca ctcagtcagc
    20161 tacgcagcat aggctcaacc ggatcacccc tgccgtccga aggatttcaa tggatttatg
    20221 agtcggtgaa gccgaacgtc tggctgattt catttagtgg tggcaccgat gtttgcagtg
    20281 gttttgtggg tggaaatccg atgttgcccg tttatgaagg cgaaatccag tgccggttgc
    20341 tgggttgtaa agtcgatgcc ttcgacgcca acgctcagcc tgtgcgcaac gaactgggcg
    20401 aaatggtgat tctggaaccc atgccttcca tgccgatctt tttctggaat gatcccggca
    20461 atgaacgcta ccgctccagc tactttgccg agtaccccgg catctggcgg cacggcgatt
    20521 ttatccgcat cacagagcgc aacggcgtaa ttatctatgg tcgctccgat gctacgctga
    20581 atcgtgatgg cgtccgtatt ggcaccgctg aaatttacag cgcggtcgaa agcctgcccg
    20641 atgttgctga tagtctggtg attggcctgg agcaaccggg cgggaagtat tttatgccgc
    20701 tgtttgtggt gctgcgcgac ggaaccaccc tgaccgacga cttggtgaaa caaatcaaac
    20761 aaacccttcg gaatcagttc agcccgcgcc atgtgcccga cgccgtctac cagatcagtg
    20821 aagtgccgta tacaatcagc ggtaaaaaac tggaaacacc ggtcaagaaa attttgtcgg
    20881 gcatggatgc gtcgttggca accagccgcg acacgctgcg taacccggca tcactcgatc
    20941 agttcacgga atttgtgctg gagcgaaaaa gt
//
