LOCUS       NZ_CP014263            20657 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Spirosoma montaniterrae strain DY10 chromosome, complete genome.
ACCESSION   NZ_CP014263
VERSION     NZ_CP014263.1
KEYWORDS    RefSeq.
SOURCE      Spirosoma montaniterrae
  ORGANISM  Spirosoma montaniterrae
            Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae;
            Spirosoma.
REFERENCE   1  (bases 1 to 5797678)
  AUTHORS   Kim,M.K., Srinivasan,S. and Lee,J.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2016) Department of Bio & Environmental
            Technology, Seoul Women's University, 623 Hwarangno, Nowon-gu, Seoul
            139-774, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PacBio SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 72.42
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 01:24:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,031
            CDSs (total)                      :: 4,981
            Genes (coding)                    :: 4,945
            CDSs (with protein)               :: 4,945
            Genes (RNA)                       :: 50
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 26 of 36
            Pseudo Genes (incomplete)         :: 12 of 36
            Pseudo Genes (internal stop)      :: 2 of 36
            Pseudo Genes (multiple problems)  :: 4 of 36
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:11:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3180505
            Orig. end                         :: 3201162
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014263.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20657
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20657
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20657
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10657](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10657)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    274..287
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.18"
                     /tool="antismash"
     misc_feature    complement(336..350)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.64"
                     /tool="antismash"
     gene            446..2308
                     /locus_tag="AWR27_RS13735"
                     /old_locus_tag="AWR27_13605"
     CDS             446..2308
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0009360 - DNA polymerase III complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012924649.1"
                     /locus_tag="AWR27_RS13735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13605"
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="WP_077131686.1"
                     /transl_table=11
                     /translation="MENFVVSARKYRPATFDTVVGQEHITTTLKNAIKTNHLASAFLFC
                     GPRGVGKTTCARILAKTINCQNLTPDGEACDQCESCVSFSQNASFNIHELDAASNNSVE
                     DIRNLIDQVRYPPQSGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPSYAIFILATTEKHK
                     ILPTILSRCQIFDFNRIQPGHIAGHLAKIAQNEGITAETEALDLIAQKADGGLRDALSM
                     FDLNVTFATDRVLRYKEVLDNLHILDYDYYFKLTDLLLAGNLPQSLLTVDEILRKGFDG
                     HQFVVGLCRHFRDLLVCKDAATVQLLQVTENVRRQYLDQSARAPMSFLLSALSLGGQCD
                     MNYKQAKDQRLHTELWLMKVASLRNLLDWENLPNTLPLNGIHSTDGNVHGEVAEKKKPS
                     PDNGLTEQHFVTSEPAAGYQPTSVARNGNGHLPTPATNGHPTNGTATVVATVPVAAPPS
                     KAAPPTRPASSRLRSTVSLHAGSTQSIAEIVEEVAAPARPDKSFSFEQLQTAWVEFARL
                     RQQQTDSASEQLILNRDLVLNGTTVFLTLDNTLQPGILTEFKVELVGYLRNQLQNSQIQ
                     VEHEVRLQEVKKMIYSPQDKYNYLAEKNPALHELRKVLNLEVDY"
     gene            complement(2347..3027)
                     /locus_tag="AWR27_RS13740"
                     /old_locus_tag="AWR27_13610"
     CDS             complement(2347..3027)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS13740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWR27_13610"
                     /product="hypothetical protein"
                     /protein_id="WP_157579212.1"
                     /transl_table=11
                     /translation="MRNSYHFLVICLAMLLLLSGCRVSSPTSTLNPGYYRVLRSPESDL
                     PRRVYVIDTADSLKLLIPGTGQQRIVSAKAAQNWAFYSPKIDIDVFTLPFKVRPARSGL
                     PPQLNSNFNAALYAGRRLDFHRYTYQPVTPSFGVRKLRSQGFGYGLFAGIGSATINELV
                     TNKQINYTYEGVILDVGIAAIYDAHIFNIGLAVGVDNLMDPNRRVWLYQRQPWFGVLFG
                     LNLN"
     gene            complement(3066..3818)
                     /locus_tag="AWR27_RS13745"
                     /old_locus_tag="AWR27_13615"
     CDS             complement(3066..3818)
                     /NRPS_PKS="Domain: PKS_KR (3-166). E-value: 1.1e-13. Score:
                     43.4. Matches aSDomain:
                     nrpspksdomains_AWR27_RS13745_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018618353.1"
                     /locus_tag="AWR27_RS13745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13615"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_077131688.1"
                     /sec_met_domain="adh_short (E-value: 4.6e-37, bitscore:
                     125.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.2e-06,
                     bitscore: 25.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRTALITGATSGIGRATADAFADMEYRLILCGRREDRLQELQQK
                     LGTKTAVTTLLFDVRDREAVETAINSLPADWQTIDILVNNAGNAHGLSAIQDGDVADWD
                     QMIDGNVQGLLYVSRAVIAGMVARQRGHIINISSIAGKQTYANGAVYCASKAAVEALST
                     GMRLDLTQHGIKVTNIAPGAVETEFSAVRFKGDTERAAKVYEGFTPLEATDIADAIVYA
                     VTAPAHVTIADLTILASAQAAATTIVRK"
     aSDomain        complement(3321..3809)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AWR27_RS13745_PKS_KR.1"
                     /evalue="1.10E-13"
                     /label="AWR27_RS13745_PKS_KR.1"
                     /locus_tag="AWR27_RS13745"
                     /protein_end="166"
                     /protein_start="3"
                     /score="43.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALITGATSGIGRATADAFADMEYRLILCGRREDRLQELQQKLGT
                     KTAVTTLLFDVRDREAVETAINSLPADWQTIDILVNNAGNAHGLSAIQDGDVADWDQMI
                     DGNVQGLLYVSRAVIAGMVARQRGHIINISSIAGKQTYANGAVYCASKAAVEALSTGMR
                     "
     CDS_motif       complement(3531..3578)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWR27_RS13745_0002"
                     /evalue="2.60E-01"
                     /label="PKSI-ER_m5"
                     /locus_tag="AWR27_RS13745"
                     /protein_end="96"
                     /protein_start="80"
                     /score="4.3"
                     /tool="antismash"
                     /translation="ILVNNAGNAHGLSAIQ"
     CDS_motif       complement(3714..3803)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AWR27_RS13745_0001"
                     /evalue="5.80E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="AWR27_RS13745"
                     /protein_end="35"
                     /protein_start="5"
                     /score="22.2"
                     /tool="antismash"
                     /translation="LITGATSGIGRATADAFADMEYRLILCGRR"
     misc_feature    3904..3918
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.79"
                     /tool="antismash"
     gene            3980..4969
                     /locus_tag="AWR27_RS13750"
                     /old_locus_tag="AWR27_13620"
     CDS             3980..4969
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009280307.1"
                     /locus_tag="AWR27_RS13750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13620"
                     /product="glycosyltransferase"
                     /protein_id="WP_077131689.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.3e-30,
                     bitscore: 103.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPEFSVVIPTYQRPALLLKCLDALGRQLLARDQFEIIVVDDAHS
                     PETETAVQLFARQIARSGSPLEVRYLGQPTRRGPAAARNRGWRAARGRVVAFTDDDCLP
                     QPNWLPSALVCFQRGAQVVTGQLRFNNPSDTPIHDRTLALLETAEFVTANCFCRKSVLE
                     RVGGFEEAFDVAWDDDNDFRFKLIQAGIPVGKCPEAVVLHPIPESPWYAPIYAERRNSY
                     DALLYKRHPDLFRERMPNYRGLVLQYYVCVLSVLMALIGLLAGSVPAITLGVGTWATLS
                     ADLILRFLPDGRLDWRTIKHAILTGLATPFVSVYWRLYGAVKYKVLYW"
     gene            5102..6280
                     /locus_tag="AWR27_RS13755"
                     /old_locus_tag="AWR27_13625"
     CDS             5102..6280
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF040570.1"
                     /locus_tag="AWR27_RS13755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13625"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_077131690.1"
                     /transl_table=11
                     /translation="MLKAYHYRLYPNATQTELLNKHFGSVRYVYNWALGIKTNAYQLES
                     KTVSRFELDKQLTRLKTELTWLGEINAQALQASLRHLDSAYTRFFREKKGFPRFKSKKD
                     NRHSFQCPQNCKVDFAAGTLQLPKIGRINVVFSREFTGTIKTVTVAKSATGKVFASVLV
                     ETDDVVLVKSAPNPTTAVGIDVGLKYFATLSTGEVIANPRFLKKSLKKLRRLSRQHSKK
                     QKGSSNRNKSKIRLARQHERVTNQRNDFLHKTSTAITKRYGTVCVENLNISGMMKNSRL
                     SRAIADVSWGSFVSMLEYKCDWQGKNLVRIGRFEPSSKLCTCGTINHSLTLKDRVWTCS
                     RCGVTHDRDILAANNIVRFAFQKQNLIGMDSAESTLGERNGSLSLSQESPSL"
     gene            complement(6292..7842)
                     /locus_tag="AWR27_RS13760"
                     /old_locus_tag="AWR27_13630"
     CDS             complement(6292..7842)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015329395.1"
                     /locus_tag="AWR27_RS13760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13630"
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="WP_077131691.1"
                     /transl_table=11
                     /translation="MLDFIRQNADKLLEQTLTHVGLTFVSLLLALVAGVPLGILIARQK
                     RLASGVLGVAGVLQTVPSVALLGFLIPLLGIGVGPALVALFLYALLPIIRNTYVGITEV
                     SASVTEAARGVGMTNRQVLMKVELPLALPVIFAGVRTAAVINVGVATLAAYVAAGGLGE
                     FIFGGIALSNTNMMLAGAIPAALLAVGFDLGLARLQTLSGRKMRVGALLFVALLPLLSA
                     FYLVPISRSDKLIAGFAHEFYGRADGYPGLQKTYGLTLRPRLIDQSLMYEAIHREQVDI
                     ISGYSTDGRIRAFNLVVLADDRHAFPPYDAAPIVRKAALTRHPDLGPTLDLLAGKLTDS
                     VMTALNYEADYLRHSPERVAADFLRRTGLYKRPAPGERTETVVIGSKVFTEQYILSEIY
                     RQLLEGHTRLRVVTKTGLGGTQICFDALRTGAIDVYPEYTGTGLLVILQPTAAKLKTLS
                     MQSDLVFRFVRQEFARQYGLVWQRPLGFSNSYCLMMRRTQAQQLNLRSISDLARYQQD"
     gene            complement(7845..8558)
                     /locus_tag="AWR27_RS13765"
                     /old_locus_tag="AWR27_13635"
     CDS             complement(7845..8558)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012924932.1"
                     /locus_tag="AWR27_RS13765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13635"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_077131692.1"
                     /transl_table=11
                     /translation="MIHVRNVVKRYGTTTVVDRVSFSVARGETLVLLGTSGSGKTTTLK
                     MLNRLIEPDDGQISLDGIDVQQQDAPNLRRRIGYVIQDGGLFPHYTVAEAIATVPTLLG
                     WETDAIRARTHELIDKLQLPASVLTRYPANLSGGQRQRVGVARALAARPPVVLMDEPFG
                     ALDPFTRKHVRRELFSLSELQETTVVLVTHDVTEARELADRIALMDGGRIVQIGTPEEL
                     MSKPVNEFVRDFLEV"
     gene            complement(8566..9543)
                     /locus_tag="AWR27_RS13770"
                     /old_locus_tag="AWR27_13640"
     CDS             complement(8566..9543)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="AWR27_RS13770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13640"
                     /product="ATP-binding protein"
                     /protein_id="WP_335695386.1"
                     /transl_table=11
                     /translation="MPIHYDPAKRDLYFFLSIMGQIIVLFFITLAFNDEKNRAINGLIQ
                     KNDELVLVQNQLIQQEKMAGLGELTAGIAHEIQNPLNFVNNFADVSTELVQELKEGPLT
                     KLSDADREYADEIMNDLTQNLQKVVYHGKRASGIVKSMLEHSRMSAGEWQLTNVNALCD
                     EYIRLAYHGLRAKDKLFNATLKTDFDARLPAVNMVPQDIGRVLLNLFNNAFYAVQKRQQ
                     RATHARNTFPYAPTVSVSTKYLTQKGMPDRIEIRVRDNGLGISDAVKEKIFQPFFTTKP
                     TGEGTGLGLSLSYDIVTKGHNGQIWVESTEGQGADFIITLPATN"
     gene            complement(9633..9989)
                     /locus_tag="AWR27_RS13775"
                     /old_locus_tag="AWR27_13645"
     CDS             complement(9633..9989)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS13775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWR27_13645"
                     /product="hypothetical protein"
                     /protein_id="WP_077131694.1"
                     /transl_table=11
                     /translation="MLSKLADYFIPAQYHQHDEIRRSARLLVFVLLYGGIGQLVSIQNG
                     SLLGFPEISYLLMVGSLICLLLLFAFRRGLSLPVCANLNIAAHTVLFATQACWGAASNR
                     RAYHRCFFCLLWQC"
     gene            complement(10001..10657)
                     /locus_tag="AWR27_RS13780"
                     /old_locus_tag="AWR27_13650"
     CDS             complement(10001..10657)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TS_Pyr4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS13780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWR27_13650"
                     /product="hypothetical protein"
                     /protein_id="WP_077131695.1"
                     /sec_met_domain="TS_Pyr4 (E-value: 1.6e-17, bitscore: 61.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQPLINFRDYSPVGLLFNGIGCLLWVVAYVVLVIEIRRKKFVEM
                     PAYVAGANIGWEFVWSFIYHPNTGLLYSLSYQAAFFLDCYIFYATLRYGTKQQIHPELT
                     KYFKLFCIINFGFWILFCFMHRTEGYDTLNGANSGYIINVILSLQCLFLLLQTKDTSLF
                     SMLLAWSKMLGTGFITISLFFFFPESRFVQLLGIACFVLDSVYIYSLWRRHGKLI"
     gene            complement(10671..11930)
                     /locus_tag="AWR27_RS13785"
                     /old_locus_tag="AWR27_13655"
     CDS             complement(10671..11930)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021509.4"
                     /locus_tag="AWR27_RS13785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13655"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_077131696.1"
                     /transl_table=11
                     /translation="MLFLVLLAAGVALAGYAIWYYRMRRRAVAKAVPAEQAPLHHWTPE
                     FLDSKRHRTDPVADSVVQQILNRGEINQVNRLFSIIVADDGTLPADLPAEVRQYFDQTA
                     TLPPWADPDLIELGQQIYIRHGVLISLLLSYKSLPECYACAKGAMVLFHTARLNEQNGS
                     VDTYARRIAETAQFVMYAMSPGGLSANGRGIRAAQKVRLIHAVIRHYLRQQNWDVALYD
                     EPINQEDMAGTLMAFSALVLEGLETMNVDLTDAEREAYIHCWRVIGHLMGLDDDLIPVN
                     AADALALGHAILNHQMAASPQGQSLTKALLDFQHKLLPSFIDDEVNVEMLRFMMGNNMA
                     DLLGVPPAQRQDVEKLAGKVRFVTGVGELLDHTLLMAMLIQGISKLMLQAQIKYMDKKD
                     GLNFYLPASLTKDWGFANPA"
     gene            complement(12117..14054)
                     /locus_tag="AWR27_RS13790"
                     /old_locus_tag="AWR27_13660"
     CDS             complement(12117..14054)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018621318.1"
                     /locus_tag="AWR27_RS13790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13660"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_077131697.1"
                     /transl_table=11
                     /translation="MKNWLYSLLALTFALSAQAQNAGSFVRENYQKFEYKIPTRDGTKL
                     HTAVYVPKDASSTNKYPFLMQRTCYSVAPYGPDAYAAQVGPSGTLMRDKYIFVYQDVRG
                     RWASEGKWTNMTPNIPDPQPAAGKKGKKAQTGVATSTAGAPDESSDTYDTIEWLLKNVP
                     NNNGRVGQWGISYPGFYTAASLPDAHPALKAASPQAPVSDFFFDDFHHNGAFIQAYLFT
                     YPVFGIQTPGPTTKSWYDNAFIRTGSKDGYQWQLDLGPLKNVQNYYKDNFYWQETVEHP
                     NYDEFWQKRSILPHLKNVKPAVMTVGGWFDAEDLYGPLNIYKTIEKTSPGTYNTLVMGP
                     FGHGRWSRETGHTLHSNIYFGDSIATFYQRNIEAKFFNHFLKGTGDGKTSLPEAYLFNT
                     GRNEWRTFDKWPAAEAETRSYSLLANGALATNRTMGSPDASGNGFSEFMSDPMKPVPYT
                     EDNTTTQGFTPFNYMSEDQRFAGRRPDVLTFQTEVLTEDLTLGGEITAKLKVSTTGTDA
                     DWVVKLIDVYPPDEPNHPYMPNRNIVLGGYQQMVRSEAMRGRFRNSFEKPEPFKPSEIT
                     DVTFRLQDVLHTFKKGHRMMIQVQSTWFPLIDRNPQKYVDNIFKAEESDFQKATHRVYE
                     NSVIDVQVLK"
     gene            14291..14725
                     /locus_tag="AWR27_RS13795"
                     /old_locus_tag="AWR27_13665"
     CDS             14291..14725
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS13795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWR27_13665"
                     /product="hypothetical protein"
                     /protein_id="WP_077131698.1"
                     /transl_table=11
                     /translation="MKTHIKSLALVGLVTLFSTATTLANDNTTNTSNRTPNNILGWIAS
                     PKATLEVCTHKKNNYLVVQVKNNARQAISVGLYTTDGLELGFYPIGKRQEAHAVRFDVS
                     ELTDASYVVKVRNRHETITKTVTLVTPPQPSRQAIIAIAD"
     gene            14738..15166
                     /locus_tag="AWR27_RS13800"
                     /old_locus_tag="AWR27_13670"
     CDS             14738..15166
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS13800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWR27_13670"
                     /product="hypothetical protein"
                     /protein_id="WP_077131699.1"
                     /transl_table=11
                     /translation="MKPLLLASLLLITQIGAAFATDSLRTDPEAPSPVWVASPNASFAV
                     RTVHSLDGHLMVGINNLGQRDLTLTVWSADNRELVFLNLNRQPGHVISLDLHEYADGLY
                     RIEIANDAEKVVKDVKIATSARLARQTFVTVAGTMTRM"
     misc_feature    complement(14785..14794)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.71"
                     /tool="antismash"
     gene            15359..15781
                     /locus_tag="AWR27_RS13805"
                     /old_locus_tag="AWR27_13675"
     CDS             15359..15781
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012925343.1"
                     /locus_tag="AWR27_RS13805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13675"
                     /product="TerB family tellurite resistance protein"
                     /protein_id="WP_083733003.1"
                     /transl_table=11
                     /translation="MNETNQSLPVVTPETAVVPTAYENAQSSLYLGFGNLVYALAKADG
                     RVQNEEADAVRQLLAQQPFGDLAQYAFTLLEERNVSIEEAYAFGMRRLTDNRKALNDTL
                     KKQFIDILLHVAGAHDDTSRKEQEMIKRFRRDLRRL"
     misc_feature    complement(15804..15818)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     gene            15822..16211
                     /locus_tag="AWR27_RS13810"
                     /old_locus_tag="AWR27_13680"
     CDS             15822..16211
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS13810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWR27_13680"
                     /product="hypothetical protein"
                     /protein_id="WP_077131700.1"
                     /transl_table=11
                     /translation="MKAIKFSLLLLFLASPIFIFSNFRPAAGKLNTAVYAESSLARVRV
                     AVDKPSGMPISIRVMDQDGWPLHEQILTGDSKQANIGINLCALPDGLYRMEMAGGRTMQ
                     AYEIKLSSINNTPSGRQVNVRPTDG"
     gene            16286..17056
                     /locus_tag="AWR27_RS13815"
                     /old_locus_tag="AWR27_13685"
     CDS             16286..17056
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS13815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWR27_13685"
                     /product="hypothetical protein"
                     /protein_id="WP_077131701.1"
                     /transl_table=11
                     /translation="MKRLQYIYARLLLVALLSYTVSHSSLAQQNLFNIPAGDLTPKNKF
                     FFQHQSNFYGSAGVESKNHFVYGLGGGFEIGANVQNLKMEFRQNSPFFTTSSDTDKAAP
                     IRPLFQLTAQKFFFLNDKFKTSIGTQLGTGLNRFGQNMRGTHFTYNTWVYEPRHHVKFV
                     VGPYVTDRGTVGQGNTVGVLVGFEYPVHKKLLIMGDFISGNNATSVSVLGVNFLATKRI
                     QLCLGGLIPNPNSGNKPGVVFELNILGFDDGPSH"
     gene            complement(17102..17269)
                     /locus_tag="AWR27_RS25520"
     CDS             complement(17102..17269)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009281913.1"
                     /locus_tag="AWR27_RS25520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_198044998.1"
                     /transl_table=11
                     /translation="MNSAEHKSVPDIALVLAGVRRAVQKVVDQAKRDDTELIIADKDGK
                     PVRVKARDLN"
     gene            complement(17266..17685)
                     /locus_tag="AWR27_RS13820"
     CDS             complement(17266..17685)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018154.4"
                     /locus_tag="AWR27_RS13820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zeta toxin family protein"
                     /protein_id="WP_232325832.1"
                     /transl_table=11
                     /translation="MAFEAGRLMLQRIDYLLQQQVDFAFETTLSTRSYVHTIRRAREVG
                     YVVSLYYFWLPSAEVSKQRVAQRVANGGHNIPSEVVERRYERSLENLKKLYIPICDYFS
                     IFSNASPTPQIIASGGIQSDTEITDGSIWRQIHSL"
     gene            complement(17779..18111)
                     /locus_tag="AWR27_RS13825"
                     /old_locus_tag="AWR27_13690"
     CDS             complement(17779..18111)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019597673.1"
                     /locus_tag="AWR27_RS13825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13690"
                     /product="L-rhamnose mutarotase"
                     /protein_id="WP_077131702.1"
                     /transl_table=11
                     /translation="MRYCLALDLKDDPALIAEYERYHEAVWPDVLQSLRDAGILSMEIY
                     RVENRLVLVMDTTDDFSFDRKARMDADNPKVQEWETLMWKYQAALPSAQPGQKWISMKK
                     VFDFNA"
     gene            complement(18201..18455)
                     /locus_tag="AWR27_RS13830"
                     /old_locus_tag="AWR27_13695"
     CDS             complement(18201..18455)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS13830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWR27_13695"
                     /product="hypothetical protein"
                     /protein_id="WP_077131703.1"
                     /transl_table=11
                     /translation="MKKVMLQFKAQQEQPSLESVKQQFKLSDEAIDKEFGVIETDSTEH
                     LYVVMVDAGQQARIEKILARKAAKHPAEGFFSNPPIKPI"
     gene            complement(18505..20196)
                     /locus_tag="AWR27_RS13835"
                     /old_locus_tag="AWR27_13700"
     CDS             complement(18505..20196)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="AWR27_RS13835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_13700"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_077131704.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.5e-17, bitscore:
                     60.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANMRVIVELAPSETLAENAGMAVTDESVGLADSVKVNVAGLTLD
                     TSFPPVELVGRLDTPTADSILDPRSFVLSDNSADSTYLVRGEIDADDYEKVLKSPKVKA
                     IYADPVIEPFAVCPTGPVGTDADVERLLCTSRMRPVGMDGTGVLVAIVDTGINLDHLRS
                     RGKTPVFDAASSWVPRAGLTPGSLAVGHGTMCAYDVLIAAPNCTLADIALLQSNAPGGT
                     VMEGLLSDAVRAFNHLLTIMRNPRRRFQSMVVNNSWGMFRPSWDFPVGHPGNYSDNPNH
                     PFNLLVGNLERAGADILFAAGNCGSDCPDGRCREPGGAVFTNRIYGANSHPAVLSVAGV
                     TIDSVRIGYSTKGPGCLTHNKPDLAGFTHFRGSGVYSADGGTSAACPVVAGVVAAVRSV
                     RPYDATNPVTAPAAIRTLMTTTATDVTPSGYDLETGFGIVGGCRLIDRLFPLRVPVDFC
                     RRFPNLCGRWRWPVPNPFPNPFPWPGPFPGPQPGPFPGPQPGPGPRPGPFSAQTDDGGY
                     GDTDDSQLEGLLMQAYYQGLMASGQYPAMAHSEPQPRKKCNCGCTD"
ORIGIN
        1 gtccctttga tcacaacact aacgcccggc aatggctggt ttttttcgtc gcgcactacg
       61 cccgaaacgg gtacgtcggc cagcgcggtg agggtagtga gaaaaaatag caggaagccg
      121 acgattggtt tcccacgcag gcaggacggt atcggttttt tcataaatcg ttgagtaaaa
      181 tggcacccca ccccaacccc tccccgttag ggaggggctt attaagccgg atggttttag
      241 tccctcccta acggggaggg gttggggtgg ggtatgtgat aaaaaaagca atttaatttc
      301 attgtatagt tctataacgt cgcaaatccg acattgttac aaattgataa agcttgtaaa
      361 cacggctacc tactctattg taagcaaata aataaaccca cccggcttcg tttgcctttc
      421 cgggcctgac ccgctaactt gcggtatgga aaatttcgtg gtttcggccc gcaagtaccg
      481 ccctgctacg ttcgacacgg ttgttgggca ggaacatatt acgactacgc ttaagaacgc
      541 tatcaaaacc aatcacttag cgtcggcgtt tttgttttgt gggccgcgcg gagtcggaaa
      601 aaccacctgc gcccggattc tggcgaagac gatcaactgc caaaacctga cacccgatgg
      661 cgaagcctgc gaccaatgtg agtcgtgtgt aagtttcagt cagaatgcat cgttcaatat
      721 tcatgaactc gatgcggctt ccaacaactc ggtcgaagac atccgaaacc tgattgatca
      781 ggtgcgctac ccgccccagt cgggcaaata caagatttat attatcgacg aggtgcatat
      841 gctctcgtcg gcagctttca acgcctttct gaaaacgctg gaagaaccgc ccagttacgc
      901 catttttatt ctggcgacca ctgagaagca caaaattctg cctacgattc tgtcacgttg
      961 ccagattttc gacttcaacc ggattcagcc ggggcatatt gcgggccatt tggctaaaat
     1021 tgctcagaac gaaggcatta ccgccgaaac cgaagccctc gacctcattg ctcagaaagc
     1081 cgacggcggg ctgcgcgacg cgctcagcat gttcgacctg aacgtgactt ttgccaccga
     1141 ccgggtgcta cgatacaagg aagtgctgga taatctgcat attctcgact acgattatta
     1201 ctttaaactg accgacctac tgctggcggg caacctgcca caaagcctgc tgacggtcga
     1261 cgagattctg cgcaaaggct tcgacgggca ccagtttgtg gtgggtcttt gccgccattt
     1321 tcgcgatttg ctggtctgta aagatgctgc aacggtgcag ttgttgcagg taacagagaa
     1381 cgttcggcgg caatacctcg accaatcggc gcgggcaccg atgtcgtttt tgttatcggc
     1441 tcttagtttg ggcggtcagt gcgacatgaa ctacaagcag gcaaaagacc agcggctgca
     1501 taccgaactg tggctgatga aagtagccag cctgcgtaac ctgctcgact gggaaaatct
     1561 gcccaacacg ctgccgctca acggcatcca cagtactgat ggtaatgttc acggggaggt
     1621 ggccgaaaaa aaaaagccat cgcccgataa cggcctgact gagcagcact ttgtaacgag
     1681 cgaacccgca gccgggtatc agccaacgtc tgtcgccagg aatgggaatg gacacctccc
     1741 aaccccggcc accaacggcc acccaacgaa tggcactgct acggtggttg cgaccgtacc
     1801 cgttgccgca ccaccatcaa aagccgcccc gcctacgcgc ccggccagta gccgcctacg
     1861 ctcaacggtt tcgctacatg caggttctac gcagtctatt gccgagattg ttgaggaagt
     1921 agccgctcct gcccggcccg acaaatcgtt cagcttcgag cagttacaga cagcatgggt
     1981 tgaatttgcc cgactacggc aacagcagac cgattcggcc agtgagcagt tgattctgaa
     2041 ccgcgacctt gtactgaacg gtactacggt atttctgacg cttgacaaca cgctgcaacc
     2101 cggtattttg actgagttta aggtcgagtt ggtggggtat ctgcgcaatc agttgcagaa
     2161 tagccagatt caggtcgaac acgaggtgcg gctacaggag gtgaagaaaa tgatttacag
     2221 cccgcaggat aaatacaatt atctggccga aaaaaacccg gccctgcacg aactccgtaa
     2281 agtgctgaat ctggaggtcg attattagtg cgtgcccctg catacctatc cgacgtttgc
     2341 gggtaatcaa ttcaggttca gcccgaacag cacgccgaac cacggctgac gctggtacag
     2401 ccagacccgg cggttggggt ccatcagatt atcgacgccc acggccaggc caatgttgaa
     2461 gatgtgcgcg tcgtagatgg cagcaatacc aacatcaaga attacccctt cataggtgta
     2521 gttgatttgc ttatttgtta ccagttcgtt gatggttgcc gaaccaatac cggcaaacag
     2581 gccatagccg aagccctgac tacgaagttt gcgaacgccg aacgaaggtg taacgggctg
     2641 ataggtgtac cgatgaaaat cgagccgccg accagcatac agggccgcgt tgaaatttga
     2701 gtttagctgg ggcggcaaac ccgaccgcgc cggacgaacc ttaaacggca gcgtaaacac
     2761 gtcgatgtcg attttggggc tgtaaaaggc ccagttctgt gctgcttttg ccgaaacgat
     2821 acgctgttgg cccgttccgg gtatcaacag tttcaggctg tcggcagtgt cgataacata
     2881 tacgcgccgg ggcaaatctg attctggcga acgtagtact cgatagtatc ccggattgag
     2941 cgtactcgtc ggcgacgata cccggcaccc cgacagtagc agcagcattg ccagacagat
     3001 caccaggaaa tggtagctgt ttctcattgt taacacacgg tagatgccac attcggcatc
     3061 acgctctatt tccgaacaat ggttgttgca gcagcctgtg cgctggctaa gatcgtcagg
     3121 tcggcaatgg taacatgggc gggggccgtc acggcataca cgatggcatc ggcaatgtcg
     3181 gtggcttcga gtggcgtaaa gccttcgtag actttggcgg cccgctcagt atcgcctttg
     3241 aaacgcaccg ccgaaaactc ggtttcgacc gcgccgggtg caatattcgt cactttaatg
     3301 ccgtgctggg tgaggtcgag ccgcataccg gtgctgagtg cttctacggc ggctttactg
     3361 gcgcagtaca cagccccgtt ggcgtaggtt tgtttgccag ctatcgaact gatgtttata
     3421 atatgcccgc gctgccgcgc caccatgccc gctatcacag ccctcgaaac atacagcaac
     3481 ccctgcacat tgccgtcgat catctgatcc cagtcggcca cgtcgccatc ctgaatcgcg
     3541 ctcaggccgt gagcattacc ggcgttattg accagaatat caattgtttg ccagtcggca
     3601 ggcagcgaat taatagctgt ttcaacggct tcgcggtcac gcacgtcgaa caggagtgtg
     3661 gtaacggcag ttttcgtgcc aagcttctgt tgtagttcct gaagccggtc ttcccgacga
     3721 ccacagagga taagacggta ctccatatcg gcaaaagcat cggcggtggc ccgtccaata
     3781 cccgacgtag ctccggtaat taatgcggta cgaaacatga taggcgttaa tacgtttgca
     3841 aatgtatagt gactttggac gacaaaactg gctccaaaac ggccatctga aagatttttc
     3901 ctgatttttc agatgatgcg taacgttggc gcaagttttg ccaacgaatt acgcataaat
     3961 gcctttacca acttccacta tgataccaga attttcggtc gtgattccaa cgtatcagcg
     4021 accggctcta ctcctcaaat gtttggatgc gctgggacgg cagcttcttg cccgcgacca
     4081 gtttgaaatt attgtggttg acgacgccca ctcgcccgaa accgagacgg cggtgcagtt
     4141 atttgcgcgt cagattgccc ggtcgggtag cccgctcgaa gtacgctacc tcggtcagcc
     4201 tacccgacgt ggcccggctg cggcccgaaa ccggggctgg cgggccgctc gcgggcgggt
     4261 ggtagccttt actgatgacg actgcctgcc acaaccgaac tggcttccat cggcattggt
     4321 ttgttttcag cgcggggcac aggttgtgac cggccaactg cgttttaata accccagcga
     4381 tacccccatt cacgaccgca cgctggcgtt gctcgaaaca gcggagtttg ttaccgccaa
     4441 ttgtttctgc cgcaaatcgg tgctggagcg cgtgggtggt tttgaggaag ccttcgatgt
     4501 agcctgggac gacgacaacg attttcgatt taagctgatt caggcgggta ttccggttgg
     4561 caagtgcccc gaagccgtgg tgctgcaccc cattcccgaa agcccctggt acgcgcctat
     4621 ttatgccgaa cgccgaaata gctacgatgc cctgctctac aagcgtcatc ccgatctgtt
     4681 ccgggaacga atgcccaact accggggatt ggttctacaa tattatgtct gcgtactgag
     4741 tgtgctgatg gctttgatag gtttgttggc gggctctgta ccggccataa cgcttggggt
     4801 aggcacgtgg gcaaccttat cagccgacct gattctgcga ttcctgcccg atgggcgttt
     4861 ggactggcgc accattaaac acgcgatact gaccggatta gccacgccat ttgtgtcggt
     4921 ctactggcgg ctgtacggag cagtgaagta caaagtgctg tattggtaat agcatttacg
     4981 aaaaaagagc gtaaagcccc cgtgctttag ccgggggata taagcgatag ccgtaggcta
     5041 aggtctgtta acttctaaca ttttctattg ttaatgttaa aaatttgcgt aactttggcc
     5101 catgttaaaa gcctatcact accggctata cccgaacgct acacaaaccg agttgcttaa
     5161 caagcatttt ggcagtgtgc gttatgtgta taattgggcg ttaggcatca agaccaatgc
     5221 ctatcagctt gaatcaaaaa ccgttagccg ctttgagttg gataagcagt taacccgcct
     5281 gaaaacggaa ttaacgtggt taggcgagat taacgcacag gcattgcagg catcactccg
     5341 gcatttagat tcggcgtaca cccgcttttt tcgggaaaag aaagggtttc cccgcttcaa
     5401 gtcgaagaaa gacaaccggc atagtttcca gtgtccccag aactgcaagg ttgattttgc
     5461 agccggcacg ttgcaacttc ccaaaatcgg caggatcaac gttgtattca gccgggagtt
     5521 cacgggtact atcaagaccg tgacggtagc gaagtcggcc acgggaaaag tctttgcgtc
     5581 ggtgctggtt gaaacagacg acgttgtact ggtgaagtca gcacctaatc cgactactgc
     5641 ggtgggcatt gatgttggcc tgaaatactt tgctaccctc tcaaccggcg aagtaattgc
     5701 caacccacgt ttcttaaaga agtcgctcaa aaaactgcgt cggctttccc gccagcacag
     5761 caaaaagcag aaaggcagta gcaacagaaa taagtccaaa atcagactcg cccgccagca
     5821 tgagcgcgta actaaccagc gcaacgactt tctccacaag accagtacgg caataaccaa
     5881 gcggtacggt acggtctgcg tggagaacct gaacatatcg ggcatgatga agaacagccg
     5941 acttagccgt gccattgcgg acgtaagttg gggtagtttc gtttccatgc tcgaatacaa
     6001 atgcgactgg cagggtaaaa accttgtcag aatcggacgg tttgagccat caagcaagct
     6061 ctgtacgtgt ggcaccataa accacagcct gactctgaaa gaccgggtgt ggacgtgtag
     6121 ccgttgtggt gtgacacatg acagggatat tttggcggct aacaacatcg ttcggtttgc
     6181 gtttcagaag caaaacttaa taggcatgga cagtgccgaa tctacgcttg gggagaggaa
     6241 cggtagttta tcattgagcc aagaatctcc cagcctttag gcgggagagt gtcaatcctg
     6301 ctggtatctc gctaaatcgc tgatcgaacg cagattcagt tgttgagcct gtgttcggcg
     6361 catcatcagg cagtagctgt tgctgaagcc cagcggtcgt tgccaaacta atccgtattg
     6421 ccgggcaaat tcctgccgaa caaaccgaaa taccaaatct gattgcatag acaaggtttt
     6481 gagcttagcc gccgtaggtt gcagaatcac cagcaacccc gtgccggtat attcgggata
     6541 gacgtcaatg gcccctgtgc ggagggcatc gaagcagatt tgggtgccgc ccagcccggt
     6601 tttcgttacc acccgcagcc gcgtatgtcc ttccagcaat tgccggtaga tttcagacag
     6661 aatatattgc tccgtaaaca ccttcgatcc tatcaccaca gtctcggtcc gttcgccggg
     6721 tgcgggacgt ttatatagcc ccgttcgtct cagaaaatca gcagccaccc gttcgggcga
     6781 atggcgcaga taatcagcct cgtaatttag ggccgtcatc accgaatcgg ttagttttcc
     6841 ggccaacaga tcgagcgtag ggccaaggtc gggatgccgc gttagtgcgg cttttcgtac
     6901 tatgggagcc gcatcgtagg gtgggaaggc atggcggtcg tcggcaagca caaccaggtt
     6961 gaaagcccgg atgcggccat cggtcgagta accgctgatg atatcaacct gctcacggtg
     7021 aatagcttca tacatcaggc tttggtcgat caggcgcggg cgcagtgtga gaccgtatgt
     7081 tttctgcaaa ccaggatagc catcggcccg tccgtaaaat tcatgtgcga agccagcaat
     7141 tagtttatca gaccggctga ttggcactaa ataaaacgcc gacagcagcg gcagtaatgc
     7201 cacaaaaagt aaggccccaa cgcgcatttt tcggcccgaa agcgtctgta aacgcgccag
     7261 gcccaaatcg aagcccaccg ccagcagtgc cgccggaatg gctccggcca gcatcatatt
     7321 ggtattactg agcgcaatac cgccaaaaat aaattcaccc aaaccaccag ccgccacata
     7381 agcggccagc gttgccacac ctacgttgat gactgccgcc gtgcgaacgc ccgcaaaaat
     7441 taccggcaac gccaatggca attctacttt catcaatacc tgccgattcg tcataccaac
     7501 gccccgcgca gcttctgtta ccgacgcact tacttccgta atgcccacgt aggtgttgcg
     7561 gatgatgggc agcaatgcat acagaaacaa cgctaccaac gccgggccga cgccaatgcc
     7621 aagcaacgga atcagaaacc ccagcagggc cacgctcggc accgtttgca gcacgcccgc
     7681 tacacccagc acacccgatg ccagccgttt ttgccgggca atgagaatac ccagcggcac
     7741 acccgcaact aaagccagta acagcgagac aaacgttagc ccaacgtgtg tcagcgtttg
     7801 ctcaagcagt ttatcagcgt tttgtcgaat gaaatcaagc attcttatac ctccagaaag
     7861 tctcgtacaa attcatttac cggcttgctc atcaactcct ccggggttcc aatctgaacg
     7921 atgcgccccc cgtccatgag cgcaatgcgg tcggccagtt cgcgggcttc ggttacgtcg
     7981 tgcgtaacga ggacaacggt agtttcctgc aactcgctca ggctgaagag ttcgcgccgg
     8041 acgtgctttc gcgtgaaggg gtcgagtgcg ccaaacggtt cgtccatcag cactaccggc
     8101 gggcgggcag ctaaggctcg tgccacgcct acgcgctgcc gctgcccccc actcaggttg
     8161 gcagggtagc gggttagtac cgacgcaggc agttgcagct tatcgatcag ttcatgggta
     8221 cgggcacgaa tggcgtcggt ctcccagccg agcagcgttg gcacagtggc aatggcctcg
     8281 gctacggtat aatgcggaaa caggccgccg tcctgaatca cataaccgat gcgtcggcgc
     8341 aggttgggtg catcctgttg ctgcacgtcg attccgtcga ggctgatctg tccgtcgtca
     8401 ggttcgatga gccggttcag cattttcagc gtcgtagttt tgcccgaacc gctcgtaccg
     8461 agcagcacca gcgtttcgcc ccgcgctacg ctgaacgaca cacgatcaac taccgtagtg
     8521 gttccgtagc gtttcactac gttccgaaca tgaatcattg ggcattcaat tagttgcggg
     8581 taaggtaata ataaaatcgg ccccttgccc ttcggtactt tctacccaga tctgcccgtt
     8641 gtggcctttg gttacaatgt cgtaactgag cgataagccc agtcccgtgc cttcgcccgt
     8701 gggtttggtg gtgaagaacg gctgaaaaat cttttctttc acggcgtctg aaatgccaag
     8761 tccgttgtcg cgaacgcgaa tttcgattcg gtctggcatg cctttctgtg tcagatactt
     8821 tgtgctaacc gatactgttg gcgcgtatgg aaaggtatta cgggcatggg tggctctttg
     8881 ctgtcgtttc tgcacggcgt aaaaggcgtt gttgaagagg ttgagcagca cccggcctat
     8941 atcctgcggc accatgttta cggcaggcaa cctggcatcg aaatctgttt tcagcgtagc
     9001 attgaataac ttgtctttag ctcgcaggcc atgatacgcc agccggatat actcgtcgca
     9061 gagcgcgttt acgttggtta gttgccattc gcccgcgctc atgcggctgt gttcgagcat
     9121 actttttacg atacccgacg cccgcttgcc gtggtacaca accttttgca ggttctgcgt
     9181 caggtcgttc attatttcgt cggcgtactc cctgtcagca tcggagagct tcgttagcgg
     9241 cccttctttc agctcctgaa ccagttcggt actgacatcg gcaaagttat tgacgaagtt
     9301 gagtgggttt tgaatttcgt gggcgatgcc tgccgttaat tcgcccagtc ccgccatttt
     9361 ttcctgctga ataagctgat tctgaaccag aaccagttca tcgttctttt gaatcaagcc
     9421 gttgatggcc cggtttttct cgtcgttaaa cgccagcgtt ataaaaaaca gcacaataat
     9481 ttgccccata atcgacagaa agaaatacaa atcgcgcttg gccgggtcgt agtgaatggg
     9541 catctgccca acgctttgtt catagacgaa aaacccggtt gcaacggcca aacaaacgta
     9601 gagccaaaat atggcactac gtcggcccag tatcagcatt gccagagcag gcaaaaaaaa
     9661 caacgatgat acgcccggcg attcgatgcc gccccccaac acgcctgcgt ggcaaacagc
     9721 acggtatgag cggcaatgtt caggttggcg cagacaggca gcgatagccc ccgtcgaaag
     9781 gcaaacagca gcaacagaca aatcaggcta cccaccatca gcagatagct aatctcagga
     9841 aaacctaata gtgatccatt ttgaatggaa accagttggc ctatcccacc gtaaagcagc
     9901 acaaacacca gcagccgcgc cgatctgcgg atttcgtcgt gctggtgata ctgcgccggg
     9961 atgaaataat cggcaagttt tgagagcata gccgcgctgg tcagatcagt ttaccgtgtc
    10021 gtcgccaaag tgagtaaata tagacagaat caagtacgaa acaggcgatt cccagcagtt
    10081 gcacgaaccg gctttcggga aaaaagaaaa acagcgagat tgtgataaat ccggttccga
    10141 gcattttcga ccaggccagc agcatcgaaa acagcgaggt atctttggtt tgcagcaaca
    10201 aaaacaggca ctgcaacgac agaatcacgt tgatgatata gcccgaattg gccccgttga
    10261 gcgtatcgta cccctctgtc cggtgcataa aacagaataa tatccagaag ccgaaattaa
    10321 tgatacagaa cagtttaaag tattttgtca gttcggggtg aatctgttgt ttggtgccgt
    10381 agcgcagggt ggcgtaaaaa atgtagcagt ctaaaaaaaa cgcggcctga taactgagcg
    10441 agtaaagcaa ccccgtgttg gggtggtaaa taaaactcca gacaaactcc cagccaatgt
    10501 tcgccccagc cacgtaagca ggcatttcga caaacttttt ccggcgaatt tcgatcacca
    10561 gcactacgta ggctactacc cacaataggc aaccaatgcc gttaaaaagt aagcctacag
    10621 gcgagtaatc cctaaaatta attagcggtt gatccatcgt agcggtgtgt ttaggccgga
    10681 tttgcgaaac cccagtcttt ggtgagcgat gcaggcaggt aaaaattcag cccgtctttt
    10741 ttgtccatat actttatttg cgcctgaagc atcagtttac taataccctg aatcagcatc
    10801 gccatcaaca acgtatgatc gagcaattcg cccacgccgg tcacaaaccg cactttacca
    10861 gctaattttt caacgtcttg tcgttgggca ggtggcacac ccagcagatc ggccatgttg
    10921 ttgcccatca taaaccgcag catctcaacg ttcacctcat cgtcgatgaa cgacggcagc
    10981 agtttatgct gaaaatcgag cagggcttta gttaatgact ggccctgcgg gctggccgcc
    11041 atttgatggt tcagaatagc gtggccgagg gcgagcgcgt cagccgcgtt gactggaatc
    11101 aggtcatcgt ctaaacccat caggtggccg attacccgcc agcagtggat ataggcttcc
    11161 cgctcggcgt cggtcaggtc aacgttcata gtttcaagcc cctccagaac cagggcagaa
    11221 aacgccatca gcgtaccggc catgtcttcc tgattaatcg gctcatcgta caaagccacg
    11281 tcccagttct gttgtcgcag atagtgccga attacggcgt gaatcagccg cactttctgg
    11341 gccgcccgaa tgccgcgccc attggccgac aaaccgcccg gcgacatcgc atacatcaca
    11401 aattgagcgg tttcggcaat gcgtcgggcg taggtgtcta ccgagccgtt ttgttcgttg
    11461 agccgggccg tatgaaacag caccatcgca cctttagcac aggcataaca ttcgggcagc
    11521 gatttgtagg atagcagcag gctaatcagc accccgtgcc gaatgtaaat ctgctggccc
    11581 agttcaatca ggtcggggtc ggcccagggc ggcagcgtag cggtttggtc aaagtactgg
    11641 cgaacctcgg cgggcaggtc ggcgggcagc gtaccatcgt cggctacgat gatgctgaac
    11701 aggcgattga cctgatttat ctcgccccga ttcaaaatct gctgcaccac actgtcggca
    11761 acggggtcgg ttcggtggcg tttgctgtcg agaaattcgg gggtccagtg atggagcgga
    11821 gcctgttcgg ctggtacggc ctttgctacg gcgcgtcggc gcattcgata ataccagatg
    11881 gcatagccgg ccagcgcaac gccagcggca agaagtacaa gaaacagcat aggtgagaga
    11941 gcagaaagga cgggtttgtt ctcccacaaa atgcattaat tatcagtgcg ttaccaaata
    12001 tatatagtta acggagtagt gggttgcaag aagtgccatt gggttcgggc aatacggtta
    12061 cgaaaccgcg cccaaaccca acgacgttct gctaaaactt ccaacaaagc gtatgcttac
    12121 ttcagcactt gcacgtcaat caccgagttt tcgtaaaccc ggtgtgttgc tttctgaaaa
    12181 tctgactcct cagctttgaa aatattatcg acgtacttct gcgggttgcg gtcgatgagc
    12241 gggaaccagg tgctttgtac ctgaatcatc atccggtggc cctttttgaa tgtatgcagc
    12301 acgtcctgca agcggaatgt tacgtcagta atttcgctgg gtttgaacgg ttcgggtttc
    12361 tcgaacgagt tgcggaaccg cccgcgcatc gcttctgacc gcaccatctg ctgatagccg
    12421 cccagcacga tgtttcggtt gggcatatac ggatgattcg gctcgtcggg cgggtacacg
    12481 tcaatgagtt ttaccaccca gtcggcgtcg gtgccggtgg tgcttacttt cagtttggcc
    12541 gtaatttcgc cccccagcgt cagatcttcg gtcaacacct cggtctggaa ggtcagtacg
    12601 tcgggccgcc gaccggcaaa ccgctgatct tccgacatat agttaaacgg cgtaaagccc
    12661 tgcgtcgtgg tgttatcttc ggtgtagggc accggcttca ttgggtcaga cataaactcc
    12721 gaaaagccat taccgctcgc atcgggcgat cccatagtgc ggttggttgc cagcgcaccg
    12781 ttcgccagca gcgaataact ccgggtttcg gcttcggcag cgggccattt gtcgaacgtg
    12841 cgccactcgt tgcggcccgt gttgaacagg taagcttcgg gcaaactggt tttgccatcg
    12901 ccagtgcctt tcaggaaatg attaaaaaac ttcgcttcga tgttgcgctg gtaaaacgta
    12961 gcgatgctgt cgccaaaata aatgttcgag tggagtgtgt ggccggtttc gcggctccag
    13021 cggccatgcc caaacggccc catcacaagc gtgttgtagg tgccgggcga cgttttctct
    13081 atggttttgt agatgttcaa cgggccgtag aggtcttcgg cgtcgaacca gccacctacg
    13141 gtcatcacgg cgggtttaac gtttttcaag tgcggcaaaa tgctgcgctt ctgccagaac
    13201 tcgtcgtagt tgggatgctc aacggtttcc tgccagtaaa agttatcctt gtaatagttc
    13261 tgcacattct tgagcgggcc gagatcaagc tgccactgat aaccatcttt cgagccggtg
    13321 cggataaacg cattatcgta ccacgatttg gtggtggggc cgggcgtttg gatgccgaat
    13381 accggatacg tgaacagata tgcctgaata aacgcgccgt tgtggtgaaa atcgtcgaag
    13441 aaaaaatctg acacgggtgc ctgtggcgac gcggctttca gagccgggtg cgcgtcgggc
    13501 agcgaggccg ccgtataaaa accggggtaa ctgatgcccc actgccctac ccgaccgttg
    13561 ttgttcggca cgtttttcag cagccattca atagtatcat acgtatccga actctcatcg
    13621 ggcgcacccg ccgttgacgt agcgacgccc gtctgcgctt ttttgccttt cttaccggct
    13681 gcgggctgcg gatcgggaat atttggcgtc atgttggtcc atttaccttc cgatgcccac
    13741 cgaccgcgca cgtcctgata cacgaaaatg tacttatcgc gcatgagcgt acccgacggg
    13801 ccaacctgag ccgcataagc atcggggccg taaggagcca cgctgtagca cgtccgctgc
    13861 atcagaaacg ggtatttgtt ggtagacgag gcatctttcg gcacgtaaac ggcagtgtgt
    13921 agtttcgtac cgtcgcgcgt ggggattttg tactcaaatt tctggtaatt ctcgcggacg
    13981 aaactaccag cgttctgcgc ctgcgccgac agggcaaatg ttagcgcaag caggctatat
    14041 agccagtttt tcatgttgaa attggagttg ggaggttatg aattcgtaaa gataatcgcc
    14101 agtaggcata gtcggtagac ttcgcgtgtt tggttctaat agctttctaa taatcagtta
    14161 attcggcttt aagataaggg ctgcaatttt gtatcaacca aagcggaaac gcagcgggct
    14221 atcactcaac aggccgcttt ccgattcgca ccggttcatt acacttcatc aacaaacacg
    14281 tatcattctc atgaaaacgc acataaaatc gctcgcttta gttggtttag taaccctttt
    14341 ctcgaccgct acgacgctgg cgaatgataa taccacgaac accagcaacc gcacacccaa
    14401 caatattctg ggttggatag caagccccaa agccacgctt gaggtttgta cgcacaaaaa
    14461 gaacaactat ctggtggtgc aggtgaaaaa caacgcccgg caagccatca gcgtaggtct
    14521 ctacacaacc gatgggctgg agttaggctt ctaccccatc ggcaaacgcc aggaagccca
    14581 cgccgttcgg ttcgacgtat cggaacttac cgatgccagc tacgtggtaa aagtgcgcaa
    14641 tcgccacgag acgatcacca aaacggtgac actcgttact ccgccccaac cctcccggca
    14701 ggcaattatt gccattgccg actaaccaac tactactatg aaaccgctcc tgcttgccag
    14761 cctgctgctt atcacgcaaa ttggggccgc gttcgcaacc gattcgctgc gcacagaccc
    14821 ggaagcaccg tcgccggtgt gggtggcatc gcccaatgca tcgtttgcgg tccgaaccgt
    14881 acattcgctc gatgggcatc tgatggtggg aatcaataac ctcggtcagc gcgatctgac
    14941 tctgacggtc tggtcggcgg ataatcgtga gctggtattc ctgaatctca accggcaacc
    15001 cggccacgta attagcctcg acctgcacga atatgccgac gggctgtacc gcatcgagat
    15061 tgccaacgac gctgagaagg tggtaaaaga cgtaaaaatt gcaacctcgg ccagattagc
    15121 ccgacaaacg tttgtgacgg tagcaggcac tatgacccga atgtaatagc tgattgcttc
    15181 gttttctgca aaaagctctg gccgtatcgg tcggggcttt ttttattggc aacacgccct
    15241 tttctaatgc ctttctaatc gaaccctaac ctgcacttaa acccggtggt gaatctttgc
    15301 agtgtcaagt taacacacaa atatgtgtct gacgaacacg ttgtttacgc taaaaatcat
    15361 gaacgagacc aaccagtcat tgcccgtagt tacgccagaa acggctgttg taccaaccgc
    15421 ttatgagaat gcccagtcga gcctgtattt aggctttggc aacctcgtgt atgcgctggc
    15481 aaaagcagat ggtcgggttc agaacgaaga agccgatgcg gtgcggcagt tgctggccca
    15541 gcagccattc ggagatttgg cgcaatacgc gtttacactg cttgaagagc gcaacgtatc
    15601 tattgaagag gcttatgcct tcgggatgcg tcggctaacc gataaccgga aagccctgaa
    15661 cgacacgctt aaaaagcagt ttatcgacat tcttctgcac gttgccggtg cccacgacga
    15721 tacgtcgcgg aaagagcagg agatgattaa gcgattccgg cgcgacctcc ggcggctgta
    15781 agcggctgga tatgtttaac ttctaaaatt gattttcact catgaaagcc ataaaattct
    15841 cgttgctgct actgttttta gccagcccca ttttcatctt ctccaatttt cggcccgctg
    15901 cgggtaaact gaacacggct gtttatgccg aatcgtcgct ggcgcgggtt cgcgtagcgg
    15961 tcgacaaacc cagcggtatg cctatttcga ttcgggttat ggatcaggac ggctggcccc
    16021 tgcacgagca aatactgaca ggtgactcaa agcaggccaa tataggtatt aacctgtgtg
    16081 cgttgcccga tgggttatat cgtatggaaa tggccggtgg ccgaacaatg caagcctacg
    16141 agatcaaact ctcatcaata aacaatacac cctccggtcg gcaggttaat gtccggccaa
    16201 ccgacgggta attgcaaaac acccccgctg gcaaatgcca gcgggggctt ttttcaacaa
    16261 acgtttgtca cacacaactc accccatgaa acgccttcag tacatttacg cacgcctttt
    16321 acttgttgcc ttactaagct acacagttag tcactcatcg ctggcacagc aaaatctgtt
    16381 caacataccg gctggcgatc ttaccccgaa gaacaagttt ttctttcagc accagagcaa
    16441 tttttatggc tcggcgggcg tcgaatcaaa aaatcacttt gtatatggtt tgggcggagg
    16501 ctttgaaatc ggagccaacg tgcagaacct gaaaatggag tttcggcaaa attcgccatt
    16561 tttcactacc agcagcgaca ccgacaaagc cgcccccatt cgtccgctgt tccagcttac
    16621 ggctcagaaa tttttctttc tgaacgacaa gttcaaaacc agtatcggta cgcaacttgg
    16681 cacgggcctg aaccgcttcg ggcagaacat gcgcggcaca cacttcacct acaatacatg
    16741 ggtgtatgaa ccccgccatc acgtcaagtt tgtggttggc ccttacgtaa ctgaccgggg
    16801 aacggtaggg cagggcaata ccgttggggt gctggttggg ttcgagtacc cggttcacaa
    16861 gaaattactg ataatgggcg attttatttc ggggaacaat gccacgagcg tatcggtact
    16921 gggtgttaac ttcctggcga ccaagcgtat tcagctttgc cttggcgggc tgattcctaa
    16981 ccccaacagc ggcaacaagc ccggcgttgt atttgagctg aacattctgg gcttcgacga
    17041 cggcccatcg cattaacgct caaacaggcc agggtacgtt gcctgtcggc ttgtttgggc
    17101 gttagtttaa gtcccgcgcc ttcacgcgaa cgggcttacc gtctttatcg gcaatgatga
    17161 gttcagtatc atcacgtttt gcctggtcta cgaccttttg cactgcccga cgtaccccag
    17221 ctaacaccag tgcgatgtca ggaactgatt tatgttctgc tgaattcata aactatgtat
    17281 ttgccgccaa atagaaccgt ctgttatttc agtatcagat tgaatgccac ctgacgcaat
    17341 gatttgcggt gttgggcttg cattactaaa tatactgaaa taatcacaaa ttggaatgta
    17401 tagtttcttt aggttttcca gactacgctc ataacgtcgt tccactactt cagaggggat
    17461 gttatgtcca ccatttgcta ctcgttgcgc tacccgctgt tttgaaactt cggctgatgg
    17521 tagccaaaag tagtataaac tcactacata ccccacttct ctggcccgtc gaatcgtatg
    17581 aacatacgag cgggttgaca gtgtagtttc aaaagcaaaa tcaacctgct gctgcaacag
    17641 ataatcaatt cgttgcagca ttaatcgacc agcttcaaat gccacgcttt cagcattgaa
    17701 tggtgaaagc ccccgcgcaa tttcgtcggc attaacaaac tcgttccagc cccattcggt
    17761 ccagccaaaa tatacagatt aggcattgaa atcaaatact tttttcatcg atatccattt
    17821 ctgaccgggc tgagccgagg gcagggccgc ctgatacttc cacatcaacg tttcccattc
    17881 ctgcaccttc gggttgtcgg catccatgcg ggctttgcgg tcgaacgaaa aatcgtcggt
    17941 ggtatccatc accagcacaa gtcggttttc aacgcggtat atttccatac tcaggatacc
    18001 ggcgtcgcgc agactttgga gtacgtcggg ccaaacggct tcgtggtagc gttcgtattc
    18061 ggcaataaga gcggggtcgt ctttgaggtc aagggcaagg cagtagcgca tgagcaggca
    18121 ccgaattaat cagcatagat gatacgtcgg gtaaagtacg cacgcatcat ttactaaccc
    18181 tgcccggcag cttatttttc tcaaatcggc ttgatgggcg gattcgagaa aaagccttcg
    18241 gcggggtgct tggctgcttt gcgggccagt attttttcga tccgggcctg ctgaccagca
    18301 tcgaccatta ccacatacag gtgttccgtc gaatcggttt ctataacgcc aaactctttg
    18361 tcgatggcct cgtcggacag tttaaactgc tgtttcaccg actccagcga gggctgttcc
    18421 tgctgggctt tgaactgcaa cattaccttt ttcatcgcgt tgaacgtaaa tggggtaggc
    18481 agtgcgtgcc taccccatgt ttggttagtc tgtacaaccg caattacatt tttttcgggg
    18541 ctgtggttca ctatgggcca tggccgggta ctgccccgaa gccataagcc cctgataata
    18601 agcctgcatc aataaaccct caagctgact atcgtcggta tctccatagc caccatcatc
    18661 tgtctgcgct gagaatggcc ccggacgcgg acccggtccg ggttgtggcc ccggaaatgg
    18721 gccgggttgt ggtcccggaa atggtcccgg ccaggggaac gggttcggaa acggattggg
    18781 aacgggccac cgccaccgtc cacacagatt cggaaagcgt cggcagaaat caacgggcac
    18841 acgcagcgga aacagccggt caatcaggcg gcatccgcct acaataccga aacccgtttc
    18901 gaggtcatag cctgacggag tgacatcggt ggccgttgtt gtcatcagcg ttcggatagc
    18961 tgccggtgcc gtaactggat tggtggcatc gtagggtctc accgaccgca ccgcagccac
    19021 cacgcccgcc actaccggac aggccgccga cgtacctcca tctgccgaat acacgcccga
    19081 tccccgaaaa tgcgtgaagc cggccagatc gggtttgtta tgggtcaggc agcccggccc
    19141 ttttgtagaa tagccaatac gcacactatc aatcgttacg ccagcaacgc tgagcactgc
    19201 cggatggctg ttggctccgt aaatacgatt cgtgaacacg gctccgcccg gttcccggca
    19261 acgcccgtcg gggcaatcgg agccgcagtt tccggcagcg aacagaatat cggcacccgc
    19321 ccgttccaga ttaccaacca gcagattgaa cgggtgattt gggttgtcgc tgtagttacc
    19381 cggatgccct accggaaaat cccacgaagg ccgaaacata ccccagctat tgttgactac
    19441 catcgactgg aaccgtcggc gcggattgcg catgatggtc agcaggtgat taaacgcccg
    19501 caccgcatcg gagagtagtc cctccataac ggtgccgccc ggcgcgtttg actgaagcag
    19561 agcaatgtcg gccagtgtac agtttggtgc ggcaatcagc acgtcgtaag cacacatggt
    19621 gccgtgccca accgctaagc taccgggtgt cagaccggca cggggcaccc aactcgatgc
    19681 ggcatcgaac actggcgttt tgccccgtga gcgcagatgg tcaaggttta tgcccgtatc
    19741 gacaatggca accagtacgc cggtgccatc catgccaacg gggcgcatcc gactcgtaca
    19801 tagcaaccgc tccacgtcgg cgtcggtgcc aacgggtcct gttggacaaa cagcgaacgg
    19861 ttcgataacc gggtcggcgt aaatggcttt gactttcggg cttttcagca ccttctcgta
    19921 gtcgtcggca tctatctcgc cccgaaccag gtaggtcgaa tcggcggaat tatcgctcag
    19981 cacgaacgaa cgcgggtcaa gaatggagtc ggcggtgggc gtatcaaggc gaccaaccag
    20041 ctcgacgggc gggaagctcg tatctaacgt aagcccggcc acattcacct taacactgtc
    20101 ggcaagccct accgattcgt cggtaacagc cataccggca ttttcagcca gggtttcaga
    20161 cggagccaat tctacaatta ccctcatgtt tgccatagta actaaagttt aacggtttag
    20221 gaatcaacca ttagtcgcaa cggcagcgag ttgggcgaac aggtaatcaa acaaaaaacc
    20281 cggctcagtc tacaagccgg gttttttaat agagggttca gaacttattg cagattagcg
    20341 tcttcgcggc tattgaaggt atcgccctga ttgaggtcgc cggttttcag ccctttcgag
    20401 aaccagtaca tgcgctgggc ggaagtgccg tgggtaaacc catcgggtac tacatacccc
    20461 tgcgtttctt tctgaatgcg gtcgtcgcca atggcattgg ctgctgtcag agcctcctca
    20521 acgtcgcccg gttcaaatgt aaacgttttg ccctgtgcat ggtgcgccca tacgcccgcc
    20581 agatagtcgg cttgaagttc gagccgcacc gacatccggt tggcctgccg ttcgttcatt
    20641 tgctgctgtg ccgaatg
//
