LOCUS       NZ_CP014263            24708 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Spirosoma montaniterrae strain DY10 chromosome, complete genome.
ACCESSION   NZ_CP014263
VERSION     NZ_CP014263.1
KEYWORDS    RefSeq.
SOURCE      Spirosoma montaniterrae
  ORGANISM  Spirosoma montaniterrae
            Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae;
            Spirosoma.
REFERENCE   1  (bases 1 to 5797678)
  AUTHORS   Kim,M.K., Srinivasan,S. and Lee,J.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2016) Department of Bio & Environmental
            Technology, Seoul Women's University, 623 Hwarangno, Nowon-gu, Seoul
            139-774, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PacBio SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 72.42
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 01:24:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,031
            CDSs (total)                      :: 4,981
            Genes (coding)                    :: 4,945
            CDSs (with protein)               :: 4,945
            Genes (RNA)                       :: 50
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 26 of 36
            Pseudo Genes (incomplete)         :: 12 of 36
            Pseudo Genes (internal stop)      :: 2 of 36
            Pseudo Genes (multiple problems)  :: 4 of 36
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:11:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 485549
            Orig. end                         :: 510257
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014263.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24708
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24708
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24708
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14708]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14708
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            45..524
                     /locus_tag="AWR27_RS02060"
                     /old_locus_tag="AWR27_02050"
     CDS             45..524
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS02060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AWR27_02050"
                     /product="hypothetical protein"
                     /protein_id="WP_077129655.1"
                     /transl_table=11
                     /translation="MKPNQLFRMAVVGVLWLSMGVGCRKEEPDIDAPVFPLVCNDGTCC
                     LAQPGRSYYHVADVNGAEMNIRGGLSPGVHFKELQPQKFNTTLPVQNEKAYMKVMEICK
                     LSLKNAGGVPLVPWDEPVTTFPYRVWGKIYNDPNFATWDAKPVNYLYIDRIEVIK"
     gene            570..3641
                     /locus_tag="AWR27_RS02065"
                     /old_locus_tag="AWR27_02055"
     CDS             570..3641
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014869.4"
                     /locus_tag="AWR27_RS02065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02055"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_077129656.1"
                     /transl_table=11
                     /translation="MNRFTAPLLLGLLCCFVSTATIAQNKFKPKYLRENDKTLLNLTSY
                     ASDNGWLDFKQDAQTEAIDPDAFLNRFGNKLGVGNGYHLKPTKDETDFREIRHQTFQLY
                     YKNIKVEGVEYTLHSRHKRLRTAHGRIIEGLSTDVSKPMPERKALEIALADLNINADEL
                     KGRDMPKGELVLISTDEALSAQNVKLCYAFDMRIAGLKNKAAKASEPQRIYVDASTGEV
                     VQRAALSSQCFNPAHQHQPALLPLRPHLALPGTGNSLVAQPMVASTFTPFSVNNNRYFG
                     AQGVGNFETEPVSTSAGQQYRLSLPGTNLRVRDAYGAVPGPATTNMELWQNGRDIFNPT
                     PHWGTNHQVGTMALWLTQRIYPFYEQIDQQQRGIDRNGQYPLVVININDTRASWDNIAA
                     IGFGQSNNVHYVTADILGHEYTHAVTQNNSNLGTGAEYKREPGALNESVADIFGTAFER
                     YLFPDGNQTNPSNWNWTLGEDGQGAFTQRSMANPEAFRQPSRYGAVDPNWFPANQAVSC
                     NSLNNLCGVHINSGVMNKWFHTLCTGQFPAGTHAMNAIAFDDAIKIVYRAVRHYTHSTS
                     NYADMRDATASAARDLFFSCSPQHRAVVEAWRLANLPSPHRCDPGCDFDVSPNVVSNAG
                     CNQAITLNATCSSPLAWPCSGLSFSYSGPNVPYNSGGAAFNVTTPSSSGHYRYTVKLAK
                     PGCYTPEKTFHVSVNCLSSGLCDFGSDPRYVGTWYGLTVQIRHINGKNVLVTAITGSNP
                     DKYYPRGDNFWGSFSLDPNAANLQGCLNAGSTGWGGLSLPGGLTPPPGYSQGTEADGAV
                     YFVANGGPPPANPCDFSQPRHVGTWNGLNVQIRQFPNNKRALVTAEPNSSNDKYYPRGD
                     NFWDNFTKTSDAEQYRACLNAGNTGWWGMSFPSISPPGGYQQGNAPDGAIFFSTNGLRK
                     AASAGPTPENVSLVTVRPNPAQTVITVGFVLAEAQRVSMQLLDLQGRTVKQQSHAGVAG
                     MNEPVLNIASLPAGQYMLEVRLGTERIMQKVIKE"
     gene            3949..5511
                     /locus_tag="AWR27_RS02070"
                     /old_locus_tag="AWR27_02060"
     CDS             3949..5511
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012927581.1"
                     /locus_tag="AWR27_RS02070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02060"
                     /product="bifunctional response regulator/alkaline
                     phosphatase family protein"
                     /protein_id="WP_077129657.1"
                     /transl_table=11
                     /translation="MQNYSILWADDEIDLLKPHILFLKNKGYDITPVNSGADALDQVEQ
                     VNYDVVFLDEMMPGMTGLETLQQIKQIRPNLPVVMITKSEEEHIMEEAIGSKIADYLIK
                     PLNPNQILLSVKKILDNKRLVTERTNIGYQQDFRNISMQYNDRMDHEEWADVYKKLIYW
                     ELELDASQDKSMGEVMNMQKSEANATFCKFIMDNYEDWLNDPKADSPVMSHQLMRKKVF
                     PLLTQGDSSPLFFILIDNLRYDQWKAIEPLLADYFTVEEESPYYSILPTTTGFARNAIF
                     SGMMPSEMERKHPDLWVNDDNEDEGLNNHEDEFLRRQLQQSRLDIKMSYHKILNVNQGK
                     SLVDNFNNLLQNQLNVVVYNFVDMLSHARTDMAMIKELAPDESAYRSITRSWFLHSPLL
                     EFVQKIAAKGGRLVVTTDHGMIRVQKPAKIVGYRETNTNLRYKQGKNLGFDDNHLFVGR
                     KPERLFLPKPHVSTAYVFTLEDYFFAYPNNYNYYVNHYRNTFQHGGVSLEEVIIPFAYL
                     KSK"
     misc_feature    complement(5558..5574)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.04"
                     /tool="antismash"
     misc_feature    5570..5586
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            5812..5979
                     /locus_tag="AWR27_RS25165"
     CDS             5812..5979
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AWR27_RS25165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157579083.1"
                     /transl_table=11
                     /translation="MRKKLTTKQQQHVIRQTLTPTEINRLENYPDARPVSHTEFESLIA
                     ASKKQVKESA"
     gene            6020..8668
                     /locus_tag="AWR27_RS02075"
                     /old_locus_tag="AWR27_02065"
     CDS             6020..8668
                     /GO_function="GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013524.4"
                     /locus_tag="AWR27_RS02075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02065"
                     /product="C25 family cysteine peptidase"
                     /protein_id="WP_232325949.1"
                     /transl_table=11
                     /translation="MRTGFCIVFCLLVSFLTKAQQPFGNEWINSTQSYVKISIVQTGIY
                     RVGYSDIRVADATLTQTNPINWQLFHRGREVAMRVVGQTDGRFDAGDYIEFYATGHDGA
                     SDSLLYRPQKRLHPYQTLFSDTTACFLTYNPGQPGRRVVERNDAAIGLAPEPFHVETVV
                     RAFTSDYSFNNLKSIEPFLQQSFYEPGEGWTGPIIKNDSVGIVTLPFVNRVRAAWPITL
                     SGMVNGRDNADHEISVQTDAALEKPIAELQSYGFLSESFEGVVKPESIQREQLSVRLQA
                     QKTAATNNFSLAYLTLTYPQTTDMGGQSAKLFRLPPGSRQTALLSVANPVPNAVAYDIS
                     DPYACRWLVVQPTDNRAQVVVGQAGLGRSVLLTNQFQKPAALRSVRFRNSFPVSANYLI
                     ITHASLRSSAVAYAAYRSSASGGGHVPFVVEADSLYDQFNYGERSPLALRQFANFMLSR
                     SSINNLLLIGRANSYPYTTKTSPDNLVPTIGYPGSDVLLTAGLRGYPINTPAIPTGRIT
                     ATANEQVLNYLRKVQQFETNTPNDLWRKQIVHVSGGKNPGEIQSLKADLGGLADLFTTS
                     LLGGSVNVFYKTTTAEVEKINIAPLVNDGVGLITFFGHAGPSVTDVNFGFASPPENGFR
                     NSRYPLMIFNGCGVGEIFSRFNTLSTDWLLAPDKGAVSVLAHSYWSYQYPTTRYLTKLY
                     GYLFDNPATLGASIGQVQQQVNQAVERESTDPFDVSVITQMVLQGDPAVRLFPLSSPDF
                     AVDAKQLFLKSLVAGRSLGSSDSLRLVVPLANAGRFVPGQSMRISIVKVGATTTTQLIQ
                     QAGFRYRDTLVYTLPKDEKLQRIDVIIDPDNQLTELTKANNRATLQIDWAKAQYSSSYP
                     PTPCPTVWHLS"
     gene            8653..9276
                     /locus_tag="AWR27_RS25660"
     CDS             8653..9276
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04183.1"
                     /locus_tag="AWR27_RS25660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="T9SS type A sorting domain-containing protein"
                     /protein_id="WP_232325950.1"
                     /transl_table=11
                     /translation="MAPQLTVFVNGAIRENKAVVGQKTNVSVLLLDENPLSISDTSAVE
                     IYLKACETCDLRKLPARMVSVSATSANQVQVDGDLQLDTGQTYQLLVFGKDAAGNRTQP
                     PYRLTVNTIASDELIAVRVYPNPAQTYARFEWDLNVRELPTDARLRIYDAAGREIGVYS
                     VSVTTGRNSMLWQAPAPGLYVYRLHLTWGDGRTERHTGKLIWQR"
     gene            complement(9273..9977)
                     /locus_tag="AWR27_RS02080"
                     /old_locus_tag="AWR27_02070"
     CDS             complement(9273..9977)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012925183.1"
                     /locus_tag="AWR27_RS02080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02070"
                     /product="hypothetical protein"
                     /protein_id="WP_077129658.1"
                     /transl_table=11
                     /translation="MRSFYRFIGFVFLLLLIGLGESCRSDEATPAPDDTAYFPLQVGDS
                     WIYWVTQQTYSVSGNVVERTFQLQQKVIRSFSQNGQPFFIIEESIRNNDRADWQINAIR
                     TVYKNPAEVVVQDNNVPKRRLLFPITTATSWNVNAYNASPDTLLRYEALNQPFRVGTRQ
                     FDQTVTVVGRNDSTLVDLNRYRQVYALNIGLVYQENESLAFCQTTPDCIGKGIIASGRR
                     QRWSLLTSNRLP"
     gene            10001..11944
                     /locus_tag="AWR27_RS02085"
                     /old_locus_tag="AWR27_02075"
     CDS             10001..11944
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009282594.1"
                     /locus_tag="AWR27_RS02085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02075"
                     /product="asparagine synthetase B"
                     /protein_id="WP_077129659.1"
                     /sec_met_domain="GATase_7 (E-value: 5.5e-15, bitscore:
                     53.6, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 4.6e-32, bitscore:
                     110.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGIAGIIRFDQQTVSPDQLVAMSDILAHRGNAVHQTVDNGVLMA
                     FGGGVDEYQPASVWAVADATVFEEGPLNQLLTDAYLTQNLSAFNGLNADFAVAIYDARQ
                     RTVSCVRDPLGVKPLYYTHVPGRFFAFASEIKALLTLPDVPTVPNEAKFREYLTWPTDY
                     VPYSAETFYRHIYSVLPGYAIRVNTHSVETVPYWTPNPAVLDGLLAPDDYAALFQERFT
                     TAIDRRMRGRERVGAHLSGGLDSSSVSCVAQQLLRKQQRPALHTFNIDTRQPEADEQNY
                     AQAVVEQWQTQHQRVTPLPDVLASVLEINRLFDRPEQFIIPSSFHLSVSQSARQVGCDL
                     LLTGHDGDSVIPTGFDYIDQLLDASEWAQLEQACHQFVSFHERDLTAVRPDWFTLNDRA
                     RYEAYVLSVLGGAVKKRFRVQSVLAFGVTLKTLQTHLRLSAGAIAAYVVRRIHRKITHQ
                     RVVNQLFTPDFQHRFAPTPASTTGERSAALSAEFGVPISQIINTTNVICNEQLNHIGAY
                     YGHEYSFPFFDRNVLELGLFTPLSVHFSNGHGRGLIRHGLRHVLPPIVAARVSKANFIG
                     YSTQAAQQLYNAAYEQFSAPSHPIWAVIDPGAFAQIKAVVFNDKYPIRRKTRYNWLLSR
                     TIYAALWLNSLR"
     gene            complement(11941..13113)
                     /locus_tag="AWR27_RS02090"
                     /old_locus_tag="AWR27_02080"
     CDS             complement(11941..13113)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.4"
                     /locus_tag="AWR27_RS02090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02080"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_077129660.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 5.8e-35, bitscore:
                     119.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPTPELQLLLLTCAFGESTERATQIRRFIQTESLDWPRVIALAE
                     RHRLTPFLYYWLRSESDIPAEIVGKLHNECRVIAADNLLKHHHYQTVKQFFNAHGIDHW
                     PLKGIFLAHDVYPESSLRPTGDLDLVINHDDVIRCVTLLRQEGYHLNRKQSLYWQRSPR
                     SVLTDWWEMSLFKPFSAGSQFDIDLHWGVAHIDHHYHLFKLPDLCRDPALLIEQQIVLL
                     VVHHGVNNVWQHIFYLNDLYFLLQKTDLNWFWLLNELRQHDIDRVFLTGLNLCQRYWSL
                     TLPDALLTDVRHERIQVMATACERRWDNPPVSLSRLVLVKLFFFLNAQTRFTRQLRALR
                     TFVVSRIFVPSTFLVGNRMVYVPKELGFLSVIGRGFRSLYRLLVPPAKPV"
     gene            complement(13110..14030)
                     /locus_tag="AWR27_RS02095"
                     /old_locus_tag="AWR27_02085"
     CDS             complement(13110..14030)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009282596.1"
                     /locus_tag="AWR27_RS02095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02085"
                     /product="serine kinase"
                     /protein_id="WP_077129661.1"
                     /transl_table=11
                     /translation="MDVIRHFYSAYGLTIDSEVVLSPLAQISPAPADLFVRYAPITPGP
                     ASEPTKIYRAGMQARFAQDGPDRLWLFWPPSLSFMALDGRELLVDANADDPDWIALFTL
                     SEAIGLILFQRGNFLLHGSAVNLSGQGVVFIGEPGAGKSTTAAAFAQQGHALISDDLVC
                     IHIDAAGKPWLIPAFPQLKIWETTVNGLQVAKTHLTPVREGVNKYAWQESLAFASSAVP
                     LSHIFVLQPPDSGRSEPQLLAPSQVPVGLLGHFPLADAMLQGEALRRYFEQSVQLARTV
                     RVATLSRPENFDRLLAFVRGLPATL"
     gene            complement(14021..14443)
                     /locus_tag="AWR27_RS02100"
                     /old_locus_tag="AWR27_02090"
     CDS             complement(14021..14443)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012925186.1"
                     /locus_tag="AWR27_RS02100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02090"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_232325951.1"
                     /sec_met_domain="PF13471 (E-value: 1.3e-21, bitscore: 75.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSSNWFKLRAIGWRKAGLLVKAFSVLLAYKSALFVFPFRYFIT
                     PHSTVRTNKPSVGQLNEVVWAVQVVSRRVPFGFTCLVQALSVRWLLRSHPAIELKIGVH
                     KSETGQFTAHAWVEHNQQIIIGEQSDQAFTPILTWT"
     gene            complement(14418..14708)
                     /locus_tag="AWR27_RS02105"
                     /old_locus_tag="AWR27_02095"
     CDS             complement(14418..14708)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020607026.1"
                     /locus_tag="AWR27_RS02105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02095"
                     /product="PqqD family protein"
                     /protein_id="WP_077129662.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-20,
                     bitscore: 71.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.3e-16, bitscore: 58.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTAFAPDTRVRARTGQASSLLGQETILLNYEAGTYYELNETGSF
                     IWSLLQNQQPVSVGELETRMLAEFDVEPAICGNELTTFLDDLLREEIIELV"
     aSDomain        complement(14427..14675)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AWR27_RS02105_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="5.70E-23"
                     /identifier="RREFam002.1"
                     /label="AWR27_RS02105"
                     /locus_tag="AWR27_RS02105"
                     /protein_end="94"
                     /protein_start="11"
                     /score="71.8"
                     /tool="antismash"
                     /translation="RARTGQASSLLGQETILLNYEAGTYYELNETGSFIWSLLQNQQPV
                     SVGELETRMLAEFDVEPAICGNELTTFLDDLLREEIIE"
     gene            complement(14710..15389)
                     /locus_tag="AWR27_RS02110"
                     /old_locus_tag="AWR27_02100"
                     /pseudo=""
     CDS             complement(14710..15389)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012927567.1"
                     /locus_tag="AWR27_RS02110"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02100"
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFSSDPVLTLDHADIYQGPKLILGDVSFQVGKGEFVYLIGRTGSG
                     KSSLLKTLYADLWLQNGKGNVAGYQLNALKSRDVPQLRRKIGIVFQDFQLFYDRSVEDN
                     LKFVLRATGWKNKTDMNNRIAEVLMQVGLGTAQKKCPISYRVASSSALSLPVPCSTNRR
                     F"
     gene            complement(15466..16134)
                     /gene="fsa"
                     /locus_tag="AWR27_RS02115"
                     /old_locus_tag="AWR27_02105"
     CDS             complement(15466..16134)
                     /GO_function="GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fsa"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012927566.1"
                     /locus_tag="AWR27_RS02115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02105"
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="WP_077129663.1"
                     /transl_table=11
                     /translation="MKFFIDTANLADIREAQQMGILDGVTTNPSLMAKEGITGKDAVMR
                     HYKQICEIVEGDVSAEVISVKYEEMIKEGDELAELDENIVVKVPMTADGIKAIKYFSEK
                     GIRTNCTLIFSAGQALVAAKAGASFVSPFVGRLDDISTDGMELIEQIVTIFTNYGYTTE
                     VLAASVRHPMHIIKCAEIGADVMTAPLSAIKALLNHPLTDIGLAKFLSDHEKANLPVKQ
                     "
     gene            complement(16147..17301)
                     /locus_tag="AWR27_RS02120"
                     /old_locus_tag="AWR27_02110"
     CDS             complement(16147..17301)
                     /EC_number="2.7.1.6"
                     /GO_function="GO:0004335 - galactokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015332045.1"
                     /locus_tag="AWR27_RS02120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02110"
                     /product="galactokinase"
                     /protein_id="WP_077129664.1"
                     /transl_table=11
                     /translation="MDLLNQLAASFQNAFNAEPTFVCSPGRVNLIGEHTDYNEGFVLPA
                     AIDKAVYLAVGPRADNELHFIAHDLSKTYVGSLDTIQKTNTWADYLLGVIAQFQQANHP
                     LRGINCVFGGTIPMGSGLSSSAALENGVGFALNELFDLGLDRISLLKLSQRAENEFVGA
                     KVGIMDMFASMMGKAGHVIKLDCRSLDYAYAPLQMEGIRIVLCDSRVKHSLVTSEYNTR
                     RAECEAGVRLLQTVYPNIRSLRDVTMTMLDTHLKEKEPHLYRRCAYVVQENQRLLDGVA
                     ALEAGDVATFGQLMYGSHEGLSRWYEVSCPELDILVGIARQQPGVLGARMMGGGFGGCT
                     INLVEARALDAFANRITEEYKRQTGKDTYLHVCKIQDGTNVISL"
     gene            17596..18315
                     /locus_tag="AWR27_RS02125"
                     /old_locus_tag="AWR27_02115"
     CDS             17596..18315
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019942435.1"
                     /locus_tag="AWR27_RS02125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02115"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_077129665.1"
                     /transl_table=11
                     /translation="MTRSSIIFCFWSLIFFGCNSANEALEQGRAHLRDGKFREAVQVLN
                     KAIEADADNAEAFNSRGVAYFELKEYANATLDYDQAIKLQPDFYRPYYNRGLLKLAQND
                     LTGALKDYSDAIRLAPDTSQRIRAEILLNRGQLFATQGQVQPAMTDFSEAIKLAPDNAL
                     ALYNRGNLRYQEKDLTGATADFQQAVRADPKFGKAFYGLGLAQVLQNQREAGCVSLKQA
                     QALGYADAANAVTGYCQ"
     gene            18332..18682
                     /locus_tag="AWR27_RS02130"
                     /old_locus_tag="AWR27_02120"
     CDS             18332..18682
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012927563.1"
                     /locus_tag="AWR27_RS02130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02120"
                     /product="transmembrane 220 family protein"
                     /protein_id="WP_077129666.1"
                     /transl_table=11
                     /translation="MRKTLSIVFGLLFVLFAAFQYNDPDPEIWVPIYGAAAVACFMAWA
                     GVGRWWFFAGMAGLYFVATWYQWPSRFEGFLFNELGMRSLNIELAREAGGLGICAAVMV
                     LFAVLTRNSVRL"
     gene            18679..19524
                     /locus_tag="AWR27_RS02135"
                     /old_locus_tag="AWR27_02125"
     CDS             18679..19524
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012927562.1"
                     /locus_tag="AWR27_RS02135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02125"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_077129667.1"
                     /sec_met_domain="HMGL-like (E-value: 6.3e-26, bitscore:
                     89.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLVECPRDAMQGLHDFVPTDLKIRYLNTLLRVGFDTLDFGSFVS
                     PKAIPQLADTAEVLAGLDLSGTQTKLLAIVANRRGAEQAAGYQQIQYVGFPLSMSETFQ
                     QRNTNKTIEQAFVEVAEIQHLSVGAGQQLVVYLSMGFGNPYGDPYSPELVSAFTERLAQ
                     MGIGIVAPSDTVGTSTPETIETLFRHLLAEFPAIEFGAHLHARPGDCSAKVRAALRAGV
                     DRIDGALRGFGGCPMATDDLTGNLPTEEIIQTLHQEGVRFTLDEQAFAEAMQLSAEVFF
                     "
     gene            complement(19529..20056)
                     /locus_tag="AWR27_RS02140"
                     /old_locus_tag="AWR27_02130"
     CDS             complement(19529..20056)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013927775.1"
                     /locus_tag="AWR27_RS02140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02130"
                     /product="hypothetical protein"
                     /protein_id="WP_077133746.1"
                     /transl_table=11
                     /translation="MQLFSDFLKLIIPASLVLYGMYLTTKLLLEREADRHRNEVKTRYT
                     ETVVPIRLQAYERMVLFLERISPNNLLLRLGNSSTTVLEFQQRLLQEIRDEYNHNLSQQ
                     VYMSQEVWEKIQAAMNEVATLINQASGDTRPDAPALDLSKRIFERIIQKDKQPTADALK
                     AVKEEIQAMFMD"
     gene            20103..20396
                     /locus_tag="AWR27_RS02145"
                     /old_locus_tag="AWR27_02135"
     CDS             20103..20396
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015814503.1"
                     /locus_tag="AWR27_RS02145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02135"
                     /product="adhesin"
                     /protein_id="WP_077133747.1"
                     /transl_table=11
                     /translation="MIDKPIVVRPEARQQIIDTLHANKIPGEYGLRVGIRGGGCGASWL
                     LGFDLPGPTDELYNVDDVRVIIDRKHLLYVLGVEIGYEPGGFTVEKSAGEGA"
     misc_feature    20471..20486
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     misc_feature    20475..20484
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            20502..24347
                     /locus_tag="AWR27_RS02150"
                     /old_locus_tag="AWR27_02140"
     CDS             20502..24347
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012927559.1"
                     /locus_tag="AWR27_RS02150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AWR27_02140"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_077129668.1"
                     /transl_table=11
                     /translation="MKRIEHHLFLVLALLAVGLSVLCYFFFEKDLPGATDEQYLSAVQE
                     RVKEETQVSANELNTIAGLVQQKKKPTFSELTVATRYPYFIFQNGQLLYWSDHRFIPDY
                     EQIKAVVQPQLVDFNESRYLVSHRQLKRQTTDVDIFSLIPIYKYYHSSNAYLQSGYNSG
                     IFSIDPQAVSTTRQKAFQAIYDHSSVFLFSVVPPKVDIYRNQSTPANTVILATLAVMFL
                     GLYVLRVLTRLKRRRQYERGFIWLSAYLVLLRALMLYFGVPFLFVESDLFNPRFYAASV
                     LVPSLGDLLLNALVVLVLALYWVNHYYRSGAYRLLLNIPKWAQTLLSLVCVASSYGVFA
                     LCYRELNNIYEKSQFTLDITLSIQFSALKLVCLLVFIVISCIYFLSLHLLVSLFIRYNR
                     RVHLGRGLFLVVLGTMLTGVFCWLAGWPVSWILLLNGVYFMLTYASQLPRTLYTFRYRT
                     SIYLFLAAFVCAAMTAYVVYNQEIRKQLVQEREFARQLLAENDEFGEFLMGKAQESIAR
                     DLEISRALRVDSVLVRERIQQRVKSLHLDKYFDKYDIEVFSFQANGKPLDISPAAPSLA
                     VLSDRYRQKNYLTKNPNIYFVNEVGNQFIKQYLCFIEIRQTDGSATSLGSSAGTTLGHI
                     VLDMRLRNERPKNVYPELLVDAKFSQQPNAPEYSYGVFSGKRLGGIQLKSEPPYGLIYS
                     AGSYNYERKMTPQLLETVIMHTEGVSANGYQHVAQRGHDGRVVVVSAAEYPFRNAFSNF
                     SFLYLLLVLTVILVIIGYAANYRLTQFSINYSTRIQILLNVAFFLPLLLVILIILGVIS
                     ANYIANQENSYINNTRNIAANFLTYLSEHMAQKRSKASMEEELGKIARDADIDINLFDT
                     QGQLYTSTRPLIYESGYLSKRINPEAYVHVIEDKENQVLLNESLGTKQYRTAYAGIKSY
                     DGKLLGILSIPYFYARPDLDRQLIEVIASALSIFTALFLFFLVLSYFASNILTKPLRML
                     TQKIRKTNLDRPNDPLLWRSDDEIGLLIREYNRMLVKLEESKQELAQNEKQSAWREMAK
                     QVAHEIKNPLTPMKLTLQHLQRTLPGSNSGETGANDAVTRRVQRTFDSLLEQIDNLSDI
                     ATSFSDFAKMPLPKNEVFEVTGVLNKAADLYADDHRIVLRRQISPGPVMVIGDRQLIGR
                     ILTNLIINAIQSVPPDRRPTIDLRLYTKDDEAQIEVHDNGAGIPEAIHTKVFLPNFSTK
                     RGGSGLGLAIAKRGIEHAGGTIWFETTEGVGTSFFVSLPLSTVGDATKLPSQTITR"
     misc_feature    24545..24559
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.11"
                     /tool="antismash"
ORIGIN
        1 aacgggtaat cttgtcgtct aaaccaacta atcgatacaa tgagatgaaa ccaaatcaac
       61 tgtttcgtat ggccgtagtg ggcgtactat ggctgagcat gggtgtcggg tgccgtaaag
      121 aggagccgga tattgacgcc cccgttttcc ctctggtctg caacgacggc acctgctgcc
      181 tggcgcaacc gggccgcagc tactaccatg tggccgatgt caatggagcg gaaatgaata
      241 tcaggggagg cctgtctccc ggtgtccact ttaaagaact tcagcctcaa aagtttaaca
      301 ccacactacc tgttcaaaac gaaaaggcgt atatgaaggt catggagatc tgcaagttga
      361 gcctgaagaa tgcgggtggc gtgcctcttg tgccctggga tgaacccgtg actacttttc
      421 cctaccgggt atggggcaag atatataatg accccaactt tgccacctgg gacgccaaac
      481 cagtgaacta cctctatatc gaccgcatcg aagtcatcaa gtgagggcat ggttgccctg
      541 tttcttacca ccgtagctaa accttgttta tgaaccgttt tactgccccc ttgctgctgg
      601 ggctgctgtg ctgttttgtc agcaccgcca ccattgccca gaataagttc aaacccaaat
      661 acctgcgcga gaacgacaaa acgctgctca acctgaccag ttatgcttcc gacaatggct
      721 ggctcgactt taaacaggat gctcaaaccg aagctattga ccccgacgct ttcctcaacc
      781 gctttggtaa caaactcggc gtcggcaatg gctaccacct gaagccgaca aaagatgaaa
      841 ccgatttccg ggaaattcgc catcagacgt tccagctcta ctacaaaaac atcaaagtcg
      901 agggtgtcga gtatacgctt cactcgcgcc ataagcggct gcgaaccgcc cacgggcgca
      961 tcatcgaggg cctgtcgaca gacgtgagta agcccatgcc cgaacgcaaa gcgttggaga
     1021 ttgccctggc cgacctcaac atcaatgcag atgagctgaa agggcgcgat atgcccaaag
     1081 gcgaattggt gctgattagc accgatgaag ccctgtcggc gcaaaacgtc aaactctgct
     1141 atgcattcga tatgcggata gcgggattga aaaacaaagc cgccaaagcc agcgaaccgc
     1201 agcggattta cgtcgatgcc agcacggggg aggtggttca gcgggccgcg ctgagcagtc
     1261 agtgttttaa cccggctcat cagcatcaac cggccctgtt gccgttgcgt ccgcatttgg
     1321 ctctgcctgg aaccggcaat tcgttggtgg ctcaaccgat ggtagcgtct accttcacgc
     1381 ctttttcggt aaacaacaac cggtactttg gcgcacaggg ggtaggcaac ttcgagaccg
     1441 aacctgtttc tacctccgcc ggacagcaat accggctgtc gctgcccggc accaatctgc
     1501 gggtgcgcga tgcctacgga gctgtacccg gtcctgccac aaccaatatg gaattatggc
     1561 aaaacggacg ggacattttc aatcccaccc cccattgggg aaccaatcat caggtgggta
     1621 caatggctct ttggctcaca caacgcattt atcccttcta cgagcaaata gatcagcaac
     1681 agcgcggaat agaccgcaat ggacagtatc cattagtggt gattaacata aatgacactc
     1741 gtgccagttg ggacaacatt gccgcaatag ggttcggtca atcgaataat gtacactacg
     1801 taacggctga tattctgggg catgaataca cgcatgccgt aacccaaaat aacagcaact
     1861 taggaacagg agcagaatat aagcgtgaac cgggtgcact taacgaatcg gtggccgata
     1921 tttttggcac ggctttcgag cggtatttgt ttcccgatgg caaccaaaca aatccttcca
     1981 actggaactg gactttaggc gaagatgggc agggcgcatt tactcagcgc agcatggcta
     2041 accccgaagc ctttaggcaa ccaagtcgat atggcgctgt tgatcctaac tggtttccgg
     2101 ctaaccaagc agtgtcttgc aactcattga ataatctatg cggtgttcac attaatagtg
     2161 gggttatgaa caagtggttt catacgctct gtacggggca gttcccggca ggtacgcatg
     2221 ctatgaatgc cattgccttc gacgatgcca tcaagattgt gtaccgggcc gttcgccact
     2281 atacccacag cacctccaac tacgccgata tgcgcgatgc tacggcatca gccgctcgtg
     2341 atttgttctt tagctgctcg ccccagcacc gggccgtggt cgaagcctgg cggctggcaa
     2401 acctgccctc gccccaccgc tgcgatccgg gctgtgattt cgatgtgtcg cccaatgtgg
     2461 tgagcaatgc cggatgcaat caggccatta cgctcaatgc tacgtgcagc agtccgctgg
     2521 cgtggccgtg ttcggggcta agtttttcgt atagtggccc aaacgttccc tacaattcgg
     2581 gaggagccgc cttcaacgta accacacctt ccagcagcgg ccactatcgg tacacggtaa
     2641 aactcgcaaa acccggttgt tatacccccg aaaaaacgtt tcacgtcagt gttaactgtc
     2701 tctcgtcggg gttgtgcgat ttcggcagcg acccgcgcta cgtgggtacg tggtacggcc
     2761 tgacggtaca gattcgccac attaacggca aaaacgtgct ggttacggcc attaccggct
     2821 ccaacccgga caaatattac ccccgtggcg acaacttctg gggcagtttc tcgctcgatc
     2881 ctaacgcggc caacttgcag ggctgtttga acgcgggcag cacgggctgg ggtgggttga
     2941 gcctgccggg tggtctgacg cccccaccgg gttattcaca gggtacagaa gccgacggtg
     3001 cggtgtactt cgtagccaat ggtggcccac cgccagccaa tccctgcgac ttcagccagc
     3061 cccggcacgt aggcacttgg aatggtctga atgtgcaaat tcggcagttt cccaataaca
     3121 agcgggcact ggtaacggca gaacccaatt cgtcaaatga taaatactac ccgcgtggcg
     3181 ataatttctg ggacaacttc accaaaacca gcgatgcgga gcagtatcgg gcctgcctga
     3241 atgcaggcaa cacgggctgg tggggtatgt cgttccccag cattagcccg cccggcgggt
     3301 atcagcaggg caatgcaccc gacggggcta ttttcttctc gaccaacggt cttcgcaaag
     3361 cggcctctgc cgggccaacg cccgaaaacg tgtcgttggt aacggttcgg cctaatccgg
     3421 cccaaactgt catcacggtg gggtttgtgc tggccgaagc gcaacgggtg tcgatgcagt
     3481 tgctcgattt gcagggccgg accgtaaagc aacaaagtca tgcgggcgta gcaggtatga
     3541 acgagccagt gctgaacatt gccagtctgc cagcgggtca atacatgctg gaggtgcggt
     3601 tgggcactga acgcattatg cagaaagtga ttaaggaata acgatttctt tctacaaatg
     3661 cccaacccgg cctcaggtgg ctgggttggg cgtttgtatg ctgtgttaaa gtatcataaa
     3721 aatcgtcctt acttcgagtg cagcgaacca cctgaacaca aacggtcgtt gagaagttaa
     3781 atccgaacca gaacgctggc ccggcaggat tagccaggat tgacaagatt accacaagat
     3841 tctacgctgc gcttagttga ttctgtaaaa caagcgaagc gcataaatcc tgttcaatct
     3901 tgtaaatcct gattaatcct ggttcagaat tccattaact tgacacatat gcaaaattat
     3961 tcgatactct gggccgatga tgagattgat ctcctcaaac cccacatcct gtttctgaaa
     4021 aacaaaggct acgatatcac gcccgtcaat agcggagccg acgccctcga tcaggtcgag
     4081 caggttaact acgacgtggt gtttctcgat gaaatgatgc ccggcatgac ggggctggaa
     4141 accctgcaac aaattaagca gatacgcccc aacctgcccg tggtgatgat taccaagagc
     4201 gaagaagaac acatcatgga agaagccatc ggttctaaaa tcgctgatta cctgatcaaa
     4261 ccgctcaacc cgaatcagat tctgctgtcg gtaaaaaaga ttctggataa caaacggctc
     4321 gtaactgagc gtaccaacat tggctaccag caggattttc ggaacatctc gatgcagtac
     4381 aacgaccgca tggaccacga ggaatgggcg gacgtgtaca aaaaactgat ttactgggag
     4441 ttggagttag atgcttcgca ggataagagc atgggcgaag tcatgaacat gcagaagagt
     4501 gaggccaatg ccaccttctg taagttcatc atggacaact acgaagactg gctcaacgac
     4561 cccaaagccg acagccccgt catgtcgcat cagttgatgc gcaagaaggt gtttccgtta
     4621 ttgacgcagg gcgacagcag ccccctattc ttcattttga tcgataatct gcgttacgat
     4681 cagtggaaag ccattgagcc gctgttggcc gattatttta cggttgaaga agaaagtccg
     4741 tattactcga ttctgcccac taccaccggc ttcgcccgca acgccatttt ttcgggcatg
     4801 atgccgagtg agatggaacg caaacatccc gatttgtggg tcaacgacga taacgaggac
     4861 gaggggctga acaaccacga agatgagttt ctgcgtcggc agcttcagca gagccggtta
     4921 gacatcaaga tgtcgtacca caaaatcctg aacgtaaatc agggtaaatc gttggtcgac
     4981 aacttcaaca acctgttgca gaatcagttg aacgttgtgg tctacaactt cgtagacatg
     5041 ctcagccacg cccgcaccga catggcgatg attaaagaac ttgcccccga cgaatcggcc
     5101 taccgcagca ttacgcggtc gtggtttttg cattcgcccc tgctcgaatt cgtacagaaa
     5161 attgcggcca aaggcgggcg gctcgttgtc acaaccgacc acggcatgat tcgggtgcag
     5221 aaaccggcca agattgtcgg ctaccgcgaa accaacacca acctacgcta caaacagggc
     5281 aagaacctcg gcttcgacga caatcacctg ttcgtaggcc gcaaacccga acggcttttt
     5341 ctgccgaagc cgcacgtatc gacagcctac gtgttcacgc ttgaggatta tttcttcgcc
     5401 tacccgaaca attacaatta ttacgtgaac cattaccgca acaccttcca gcatgggggc
     5461 gtgtcgctcg aagaagtcat tattccattc gcatatctga agtcgaagta agacgcatct
     5521 caagaatact gtaaggcagg caacgcgttt aagatgttgc ctgccttttt tgcaaaagac
     5581 acactactta cttatatagc agcttcaact tgctattagt aaagtaacca atgctgtttc
     5641 aatgggacga aaggaatttg aaaaaagttg ataaagttcg ggccagtgga cgagagttta
     5701 ccggcgtaag taatcaaatg cgcgtactgt gtgttatctt cgtggtaagg gatggtgtga
     5761 ttcgcatttt taacgtttgg agagccaaac aaaccgcttt gaaaaaatac tatgcggaag
     5821 aaactaacga cgaagcagca gcagcacgta atcaggcaaa cactgacccc aacggagata
     5881 aaccggctgg aaaactaccc tgatgcccga ccagtcagcc acaccgagtt tgaaagcctg
     5941 attgccgcca gcaaaaaaca ggtaaaagag tcggcatgat tttagttcag gatagtagcc
     6001 caatcattac gtaaccatca tgcgaacagg cttttgcatt gtgttttgcc tgctggtttc
     6061 gtttttgacg aaagcgcagc aaccgtttgg taatgagtgg attaattcga cacaatcgta
     6121 tgtaaaaatc tcgattgttc agacgggcat ctaccgcgtt ggctacagcg acattcgggt
     6181 tgccgacgct acactgacgc agactaatcc cattaactgg cagttatttc accggggccg
     6241 cgaggttgct atgcgcgtcg tggggcagac tgatgggcgg ttcgatgcag gcgattacat
     6301 tgagttttat gccacaggcc acgatggcgc gtctgattcg ctcctgtatc gcccgcaaaa
     6361 acgtctgcat ccgtaccaaa cactcttctc cgacactacc gcctgtttcc tgacgtataa
     6421 ccccggccaa ccgggtcggc gcgtagttga gcggaacgat gcggctatcg gtcttgcgcc
     6481 cgaaccgttt catgttgaaa ccgtcgttcg ggcgttcacc agcgattatt cgttcaataa
     6541 cctgaaaagt attgaaccgt ttttgcagca aagtttttac gaacccggcg aaggctggac
     6601 cggtcccatc attaaaaatg actcggtggg catcgtaacg ctgccgtttg tgaatcgggt
     6661 gcgggctgcg tggcccatca cactaagcgg catggtcaat gggcgcgaca atgccgatca
     6721 tgagatttcc gtacagaccg atgcggctct ggaaaaaccc attgccgaac tccagtctta
     6781 tggctttcta tcggagtcgt ttgagggtgt agtgaagcca gaatcaattc agcgagagca
     6841 acttagcgtc cggctccaag cccaaaaaac ggcggctacc aataattttt cgcttgccta
     6901 tctgacactg acgtacccgc agactacgga catgggcggg caatcggcca aactgtttcg
     6961 tctgccaccc ggctcgcgcc aaacggcttt gcttagtgtt gccaacccgg ttcctaatgc
     7021 cgtagcctac gacatcagcg acccgtatgc ctgtcggtgg ctggtcgtgc agcctactga
     7081 caaccgggcg caggtagttg ttgggcaggc cgggttgggt cgtagtgtcc tgctcacaaa
     7141 tcagtttcaa aaacccgcag cgttgcgttc ggtccggttt cggaatagtt ttccggtgtc
     7201 ggccaattac ctgattatta cgcacgcatc gctacggtcg tcggcggtgg cgtatgcggc
     7261 ttatcggtcg tcggcatcgg ggggtgggca tgtgccgttt gtagtagagg ccgattcgct
     7321 gtacgaccag ttcaactacg gcgaacgcag cccgctggct cttcggcagt ttgccaattt
     7381 tatgctgagt cggtcatcta tcaacaacct gttgctgatt ggccgggcca acagttaccc
     7441 gtacaccacc aaaaccagcc ccgacaattt ggtgccaacc attggctacc ccggttccga
     7501 cgtgttgctg acggcgggcc tgcgcggcta tcccatcaat acgcccgcca tcccaaccgg
     7561 tcgtatcacg gctacagcca acgagcaggt gctgaactac ctacgaaagg tacagcagtt
     7621 tgaaaccaac acacccaacg acctgtggcg taagcagatt gtgcatgtca gcgggggtaa
     7681 aaatccgggc gaaatccaaa gtctgaaagc cgatctgggc ggcttagccg atttatttac
     7741 taccagtttg ctgggcggtt cggtcaatgt tttttataaa acaactaccg ccgaagtcga
     7801 gaaaataaat attgcgccgt tggtgaacga tggggtaggg ctgattacgt ttttcggcca
     7861 tgcggggccg agcgtaaccg acgtgaattt tggctttgct tcgccccccg aaaatggctt
     7921 tcggaattcg cgctacccgc tgatgatttt caacggttgt ggcgtaggcg aaattttctc
     7981 gcggttcaat accttgtcga ccgactggct gctggctccc gacaaagggg ccgtatcggt
     8041 actggcgcat tcgtactgga gttaccaata cccaaccacg cgttacctga caaaactgta
     8101 cggttatcta ttcgacaatc cggccacgct tggcgcgtcg atagggcagg ttcagcagca
     8161 ggtaaatcag gctgttgagc gggaaagcac agacccgttc gatgtgtcgg ttattacgca
     8221 gatggtgttg cagggcgacc cagccgtgcg gctttttccg ttgtcaagtc ctgatttcgc
     8281 cgtcgatgcc aaacaacttt tcctgaagtc gctggtggct ggccgttcgc tcggcagtag
     8341 cgactcgctt cggctggtgg tgccacttgc caacgcaggc cgctttgtgc cgggccaatc
     8401 catgcgtatt tcgattgtaa aagtcggggc taccaccact acgcaactga ttcagcaggc
     8461 tggtttccgc taccgcgata cgctggtgta cacgctgccc aaagatgaga agctacagcg
     8521 catcgacgta attatcgacc cggacaacca acttacagaa ctgaccaaag ccaataaccg
     8581 ggctacgctc cagatcgatt gggcgaaagc gcagtatagc agcagctatc ccccaacgcc
     8641 ctgcccgacc gtgtggcacc tcagctaacc gtattcgtta acggggccat ccgtgaaaat
     8701 aaggctgtgg tagggcagaa aaccaacgta tcggtgttgc tgctggacga aaacccgctg
     8761 tcgataagtg acacaagcgc ggtagaaatc tacctgaaag cctgcgaaac ctgcgacctg
     8821 cgaaaactgc ccgcccgtat ggtatcggtg tcggcaacgt cggctaatca ggtgcaggtc
     8881 gacggcgatt tacagctcga taccggacag acgtatcaac tgctggtgtt tggcaaagac
     8941 gctgccggca atcgaacaca gcccccttat cgactcactg tcaatactat agcttctgat
     9001 gagcttattg ccgtgcgagt atatccgaac ccggcccaga cgtatgcccg gtttgaatgg
     9061 gacctgaacg tgcgcgagtt acccaccgac gcaaggctga ggatttatga tgcggcaggc
     9121 cgggagatag gtgtttattc cgtgtcagta acaaccggac gcaatagtat gctgtggcag
     9181 gctcctgcac ctggcctgta cgtttacagg ctccatctga cctggggcga cggtcgtacc
     9241 gaacggcata ctggcaagtt gatctggcaa cgttagggca accggttgct ggtcagcagc
     9301 gaccaccgct gccgacggcc cgacgcaatg atgcctttgc cgatgcagtc gggtgtagtc
     9361 tggcagaaag ccagcgattc gttttcctga tagaccaacc cgatgttgag cgcgtaaacc
     9421 tgtcgatacc gattcagatc aactaatgtc gaatcattgc ggcctacaac cgtcaccgtt
     9481 tggtcgaact ggcgcgtacc cacacgaaat ggctgattaa gtgcttcgta gcgcagcagc
     9541 gtatcggggc tggcattgta ggcgttcacg ttccaggatg tggccgtggt aatcgggaac
     9601 agcagccggc gtttaggcac gttgttgtct tgtacaacga cttctgctgg atttttataa
     9661 accgttcgga tggcgtttat ttgccagtcg gcccggtcgt tgttgcgaat ggattcttcg
     9721 attatgaaaa acggttgccc attctgactg aacgagcgga ttactttttg ctgcaactga
     9781 aacgttcgct ctacaacgtt gcccgataca gagtaggttt gctgcgttac ccaataaatc
     9841 caggaatcgc cgacttgcag cggaaaataa gctgtgtcgt cgggcgcggg cgtagcttcg
     9901 tcagaacggc agctttcgcc caaaccgatt aagagcagta ggaaaacgaa tccgataaag
     9961 cgatagaacg agcgcataac gggccgaaat tacaaattct atgggtggta ttgccggtat
    10021 tattcgtttc gatcagcaaa ccgtgtcgcc tgaccaactt gtcgccatga gcgatatact
    10081 ggcacatcgg ggtaatgcgg tgcaccaaac cgttgacaat ggggtgttaa tggcgtttgg
    10141 cgggggagta gacgagtacc aaccggcttc tgtatgggcc gtggccgatg caaccgtttt
    10201 tgaggaaggc cctttaaatc agctacttac tgatgcatat ttaacgcaaa atttatcggc
    10261 attcaacgga ctgaacgctg attttgctgt ggcaatctac gatgcccggc aacgaacggt
    10321 tagctgcgtt cgcgacccgc tgggcgttaa accgctctac tacacgcatg tgccgggtcg
    10381 attttttgcc ttcgcttccg aaataaaagc tctgctgacg ctgcccgacg taccgactgt
    10441 tccgaacgaa gccaaatttc gggaatacct gacttggccg accgactacg tgccgtacag
    10501 tgctgaaacg ttctatcggc acatttacag cgtattgccc ggctatgcca ttcgggtaaa
    10561 tacccattcg gttgaaacgg ttccgtactg gacgcccaat cccgccgtat tggacggact
    10621 gttggccccc gacgattacg cagcactgtt tcaggaacga tttacgaccg ctatcgaccg
    10681 ccgtatgcgc ggcagagagc gtgtcggcgc gcatctgagt ggcgggcttg attcgtcgtc
    10741 tgttagttgc gtggcgcagc agttgctgcg taaacagcaa cgacctgcat tgcatacgtt
    10801 caacatcgat acccggcagc ccgaagccga cgaacagaat tacgcgcaag ccgtggttga
    10861 gcagtggcaa acgcagcacc agcgcgtaac gcccctgccc gacgtgctgg cgtcggtgct
    10921 ggaaatcaac cggttgttcg accggccaga gcagttcatt attccctcga gctttcacct
    10981 gagcgtatcg cagtcggccc ggcaggtggg ttgcgacctg ctgctaactg gccacgacgg
    11041 cgacagcgtg attccgaccg gatttgacta catcgatcaa ctgctcgacg ccagcgagtg
    11101 ggcgcaactc gaacaggctt gtcatcaatt tgtttcgttt catgaacgcg atctgacagc
    11161 cgttcggccc gactggttta cgctgaacga ccgggccagg tatgaagctt atgtgttgtc
    11221 ggtattgggg ggggcagtga agaaacggtt tcgggtacaa tcagttttgg cattcggggt
    11281 tacgctgaag accttacaga cgcatttgcg actttcggca ggggccattg ctgcttacgt
    11341 agtcagacga atacaccgaa aaataactca tcagcgggtc gtcaaccaat tattcacccc
    11401 tgattttcag catcggtttg cgcctacccc ggcatctaca accggcgaac ggtcggcggc
    11461 tttatcggca gaatttggcg taccgataag ccagattatc aacacaacca atgtgatttg
    11521 taatgagcaa ttaaaccata ttggggcgta ttacggccat gagtacagtt tccctttttt
    11581 cgaccggaac gtgcttgaac tggggttgtt tacaccgctg tctgtgcatt tcagcaatgg
    11641 tcatgggcgc ggcctgattc gtcacgggct gcgccatgtg ttgcccccga ttgtagctgc
    11701 ccgagtgagc aaggctaatt ttatcgggta tagcacccag gcagcccagc agttatacaa
    11761 cgctgcctat gagcagttta gcgcaccatc acacccaatc tgggctgtaa ttgacccagg
    11821 ggcttttgct cagattaaag ccgttgtttt taatgacaag taccccattc ggcgaaaaac
    11881 gcgttataac tggctactga gccggacaat ctacgcggcc ctctggctga attcactgcg
    11941 ctaaacgggt tttgcaggcg gaacaagcag ccgatacaac gaccgaaacc cacgcccgat
    12001 gaccgacaaa aagccgagtt ctttgggcac gtaaaccata cgattgccga ccagaaaagt
    12061 gctgggtaca aaaatccggc tcacaacgaa cgtgcgtagg gcgcgcagtt gccgggtgaa
    12121 gcgggtttgc gcattcagaa aaaaaaatag tttgacaagt acaagacggc taagcgatac
    12181 cggcggattg tcccatcggc gttcgcaggc ggttgccatg acctgtatac gttcgtgtcg
    12241 aacatcggtt agcagggcgt cgggcagcgt gagcgaccaa tagcgttggc agaggtttag
    12301 cccagtcaga aatacgcggt caatgtcgtg ttggcgtagt tcgttcagga gccaaaacca
    12361 gttgagatcg gttttctgaa gcagaaaata cagatcgttc agataaaaaa tatgctgcca
    12421 gacgttgttg acgccgtgat gaaccaccag caacacgatt tgctgttcga tgagcagagc
    12481 cgggtcgcgg cataaatcag gcaacttgaa cagatggtaa tgatggtcaa tatgtgcaac
    12541 gccccagtgc agatcgatgt cgaactgact acccgctgaa aacggcttga acaaactcat
    12601 ctcccaccaa tcagtcagca cggatcgggg gcttcgttgc cagtataggc tttgtttccg
    12661 gttcagatgg tagccttcct gccggagtaa tgtcacgcac cgaattacat cgtcgtggtt
    12721 gattaccaaa tccagatcgc cggttgggcg caggctgctt tcgggataca cgtcgtgggc
    12781 cagaaagatg cctttcagcg gccaatggtc aataccgtga gcgttgaaaa attgcttaac
    12841 agtttgataa tgatggtgtt ttaacaaatt gtcggcggca attacccggc actcgttatg
    12901 cagtttcccg actatctcag ccggaatgtc agattcggac cggagccagt agtacagaaa
    12961 gggggtaagt ctgtggcgtt cggctaacgc aatcacacgc ggccaatcga gcgactcggt
    13021 ttggatgaac cggcgaattt gagtggcccg ctccgtcgat tcgccgaacg cgcaggtcaa
    13081 tagcagcaat tgaagttcgg gcgtgggctt catagcgttg caggcaggcc gcgaacaaaa
    13141 gccagcaaac ggtcgaagtt ttcgggacga ctcaatgttg ctacccgaac tgttcgtgcc
    13201 aattgtacgc tctgttcaaa ataccgacgt agtgcttcac cctgtagcat cgcgtcggcc
    13261 agcggaaaat gcccaagcag gccaaccgga acctgacttg gtgccaaaag ctgtggctca
    13321 ctgcggcccg aatccggcgg ctgtagcaca aaaatatgcg acagcggcac tgccgaactc
    13381 gcaaacgcca gcgactcctg ccaggcatat ttgttaacac cctcgcgcac gggcgtcaga
    13441 tgcgttttcg ctacctgaag gccattgacg gtggtttccc agattttcag ttgtgggaag
    13501 gcaggaataa gccagggttt tccggctgca tcgatatgaa tacaaaccag atcgtcgctg
    13561 atgagtgcat ggccctgctg agcgaaggca gccgccgttg tggatttacc cgcgccgggt
    13621 tcgccgatga aaacaacccc ctgcccactc agattcaccg cgctgccgtg cagtaggaaa
    13681 ttgcctcgct gaaacaggat taacccaatg gcttcgctga gcgtaaacag cgctatccag
    13741 tcggggtcat ctgcgttggc atcaacgagt aattcgcggc catcgagtgc cataaatgag
    13801 agcgatggcg gccagaacaa ccacagccgg tcagggccgt cctgagcaaa ccgggcctgc
    13861 ataccagccc ggtaaatttt agttggttcc gatgccggac cgggtgtaat cggggcatac
    13921 cgaacaaaca gatcagccgg agcgggcgaa atttgcgcaa gcggggacag tacaacttcc
    13981 gaatcgattg tcaggccata agcggaataa aaatgcctga ttacgtccat gtcagaatcg
    14041 gcgtaaatgc ctgatcgctt tgttcgccta taataatttg ctggttatgt tcaacccacg
    14101 catgggccgt aaactgcccg gtctcacttt tgtgaacccc gattttaagt tcgatagccg
    14161 gatgagatct cagcaaccaa cgcacactca gtgcctgcac cagacacgta aaaccgaatg
    14221 gtacgcgtcg gctaacaacc tgcaccgccc acacaacctc gttaagctgc ccgaccgatg
    14281 gtttgttagt tcgaaccgtc gaatgcggag tgatgaagta acggaaaggg aaaacaaaca
    14341 gcgcggactt gtaagccagc aacacggaga aggctttaac taaaagccct gctttgcgcc
    14401 agccgatggc ccggagttta aaccagttcg atgatctctt cacgaagcag atcgtctaaa
    14461 aacgttgtca gttcgttgcc gcatatggca ggctcaacgt caaattctgc gagcatccgg
    14521 gtttctaatt cgccaacgct gactggctgc tggttttgta gcaaactcca gataaagctg
    14581 cctgtttcat tgagttcgta gtacgtacca gcttcgtagt tgagcaaaat ggtctcttgc
    14641 cccagcaatg atgatgcctg ccctgttctg gctcgaactc gtgtgtcggg agcaaatgcg
    14701 gtctgcatat cagcctaaca attctatgac ctgaccgtcc tggcagcgta aaacgcgggc
    14761 cgggtatttg ttcagcaaat cgtagttatg ggttgccatc agcacggcag ttccagcgtt
    14821 attaatcgcc tgaaatacct tcataatctg gtcagaaact gccgggtcga ggttgccggt
    14881 aggttcgtcg gcgatcagaa tctgcggttc gttgagcatg gcacgggcaa tgacaacgcg
    14941 ctgctgctcg ccacccgata gctgatgggg cattttttct gagccgttcc caggcccacc
    15001 tgcatcaata cctcagcgat gcggttgttc atgtcggtct tgtttttcca gcccgtagcc
    15061 cgcaaaacaa acttcaggtt gtcttcgacc gagcgatcat aaaagagctg aaaatcctga
    15121 aaaacaatcc cgatcttccg gcgcaactgc ggcacgtcgc ggcttttaag ggcattgagc
    15181 tgataaccag ctacattacc tttgccgttt tgcagccata gatcggcata gagcgttttc
    15241 agcaacgacg actttccact gcccgttcgt ccgattaggt atacaaactc acccttgcca
    15301 acctgaaagg acacatcgcc cagaatcaat tttgggccct ggtaaatgtc agcatggtcg
    15361 agcgttagaa caggatcgga agaaaacata attcagttat cagctatcag ccaacaacca
    15421 acagtggcac ccttgaagca ctgttggttg ttggctgttg attggtcact gtttaacagg
    15481 caggtttgct ttttcgtggt cagacaggaa cttggcaaga ccaatatcgg taagtgggtg
    15541 attgagcaat gccttaatcg cgctgagggg agccgtcatt acatcggcac caatttcggc
    15601 gcatttgatg atgtgcatcg ggtgacgtac cgatgccgcc agtacttcgg tcgtgtagcc
    15661 gtaattggtg aagatggtta cgatctgctc gatcaattcc ataccatcag tcgaaatatc
    15721 gtctaaacga ccaacgaacg gcgatacgaa cgaagctccc gctttggccg ctaccaatgc
    15781 ctgacccgcc gagaaaatca gcgtgcagtt ggtgcgaatg cctttttctg aaaaatattt
    15841 gatggctttg ataccgtcgg cggtcatcgg gactttcacc acaatgtttt cgtcgagttc
    15901 ggccagttca tcgccttctt taatcatttc ttcgtattta accgaaatga cttcggcact
    15961 aacgtcgcct tcaacaatct cgcagatttg cttatagtgg cgcattacgg cgtctttgcc
    16021 ggtgataccc tctttcgcca tcagcgaggg gttggttgtt acaccgtcga ggatacccat
    16081 ttgctgggct tcgcgaatgt cggccagatt ggccgtatcg atgaaaaatt tcatggtttt
    16141 attaaattat agactaataa cgtttgtacc gtcctggatt ttgcagacgt gaaggtacgt
    16201 atctttcccc gtttggcgtt tatattcttc ggtaatccga tttgcgaacg catccaacgc
    16261 acgcgcttct actaagttga tggtgcagcc gccgaagccg ccccccatca ttcgcgcacc
    16321 cagcacgccc ggctgttgcc gcgcaatgcc aactaatatg tctaactcag ggcaactaac
    16381 ttcgtaccag cggcttagcc cctcatgcga cccatacatc aactgcccga acgtggctac
    16441 gtctccagct tccagagccg ccacaccgtc gagcagccgt tgattttcct gtactacgta
    16501 ggcgcaccgg cgatatagat gcggttcttt ttctttcaga tgcgtatcca gcatcgtcat
    16561 cgttacatca cgcagactac ggatgttggg ataaaccgtc tggaggagtc gaacgcccgc
    16621 ttcgcattcg gcccggcgcg tgttgtattc cgacgtcacg agcgaatgct ttacccgcga
    16681 atcgcagaga acgatgcgga taccttccat ttgcagcggg gcgtaggcgt aatcgagcga
    16741 ccgacaatcg agtttaatga cgtgtccggc ttttcccatc atgctggcaa acatgtccat
    16801 gatgcctact ttcgcgccaa caaattcgtt ctcagctcgt tgcgagagtt tgagaagcga
    16861 aattcgatca agaccgaggt caaataactc gtttagtgca aagccaacgc cattttcgag
    16921 ggccgccgat gatgataagc ccgaacccat cgggatagtg ccaccgaata cgcagttgat
    16981 tccccgcaat gggtgattgg cctgctgaaa ctgtgctata acgccgagca gataatcggc
    17041 ccaggtgttg gttttctgga tggtatcgag cgaaccgacg taggttttac tgaggtcgtg
    17101 ggcaataaaa tgcagctcat tatcggcgcg tgggccaacg gctaaataaa cggctttatc
    17161 gatggcggct ggcaatacga agccttcgtt atagtcggtg tgttcgccga tgaggttaac
    17221 gcggccagga gagcaaacaa atgtaggttc agcattgaac gcgttctgaa acgacgcggc
    17281 cagttggttc agtaggtcca ttcgaccggg gagcaaaaca gaagggtcgg aaaacaaaaa
    17341 atggcaaacc aatgtctcac cgctacaacc acctaccctt gcttcggtca agacctgggg
    17401 gattcagcag gagctggtag caccgatttg ccgacgcaaa gttaagcaat tgttagccaa
    17461 acgaccaaac ttaggccgta tctttgtgaa ctatctggtt tcgtaacata gagattcacg
    17521 gagagaaaga gattcgcaga gacttcgtta aatctgccaa ctcgctgagt atctctgcgt
    17581 aataactttt ttataatgac tcgctcatca atcatttttt gtttctggtc tctgattttt
    17641 tttggatgta actcggccaa cgaggctctt gaacaaggcc gggcgcattt gcgcgacggg
    17701 aaatttcggg aagctgttca ggtgttgaac aaagccatcg aagccgatgc cgacaatgcc
    17761 gaagcgttca actcgcgcgg ggtagcttat tttgaactaa aagaatacgc caacgccaca
    17821 ctcgattacg atcaggctat caaattgcaa cccgattttt accgacccta ctacaatcgg
    17881 ggcttgctga aactggccca aaacgacctg acgggtgcgc tgaaagatta ctccgacgcc
    17941 attcggctgg ctcccgatac gagccaacgc atccgggccg aaattctgct taaccggggt
    18001 caattgtttg ctacacaggg tcaggtacaa ccggctatga ccgacttttc ggaggctatc
    18061 aaacttgccc ccgacaatgc gttggcttta tataaccggg gtaatctgcg ttatcaggaa
    18121 aaagacctga ccggagcaac ggctgatttt cagcaggccg tgcgggctga cccaaaattt
    18181 ggcaaagcat tctacgggct tggtctggct caggttctgc aaaatcaacg cgaggccggt
    18241 tgtgtgagtc tcaaacaggc acaggctttg gggtatgccg atgccgccaa cgccgtaacg
    18301 ggctactgtc agtaaacatt tatttactcg tatgcgtaag actctttcta tcgttttcgg
    18361 gctgcttttt gtgttgtttg cggcttttca atacaacgat cccgacccgg aaatttgggt
    18421 gccaatttac ggcgcagcgg ctgtagcctg ttttatggcc tgggcgggcg tggggcgttg
    18481 gtggtttttt gctggtatgg ccgggctgta ttttgtggca acctggtatc agtggccgtc
    18541 tcggttcgaa gggtttttat tcaatgaact gggaatgcgt agcctgaata tcgaactggc
    18601 tcgtgaggcc ggcggactgg gtatctgcgc ggctgtcatg gttttgtttg cggtattgac
    18661 ccgcaattcc gttcgcttat gaaactcgtt gaatgccccc gcgatgccat gcaggggctg
    18721 cacgattttg tgccaaccga tctgaaaatc cgctacctga acacgctgtt gcgggttggt
    18781 ttcgacacgc tcgactttgg tagttttgtt tcacccaaag ccattccgca actggccgat
    18841 actgccgagg tgcttgccgg actcgatctt tcgggaacgc agacgaagtt actggctatt
    18901 gtagccaatc ggcgtggggc cgagcaggcg gctggctatc agcagattca gtacgttggt
    18961 tttcctctgt ctatgtcaga aacgtttcag cagcgcaaca ctaacaaaac catcgaacag
    19021 gcgtttgtcg aagtggccga gattcagcat ctatccgttg gcgcggggca acagttggtc
    19081 gtttacttat cgatgggttt cggaaacccc tacggcgatc cctacagtcc tgaattagtc
    19141 agcgcgttta cggagcggct ggcgcagatg ggtatcggca tcgtagcacc atccgacacg
    19201 gtgggcacgt cgacgcccga aaccatcgaa accctgttcc ggcatttgct ggccgagttt
    19261 ccagctattg aatttggcgc acacctgcac gcgcggcccg gcgattgttc tgccaaagta
    19321 cgggcggctc tgcgggcggg tgttgatcgc attgatggag ccctgcgtgg cttcggtggt
    19381 tgcccaatgg ctaccgacga cctgaccggc aatctgccta ccgaagagat catccaaact
    19441 cttcatcagg aaggcgttag gtttacgctc gacgagcagg catttgccga agcaatgcaa
    19501 ctatcggcgg aggtgttttt ttaggaagtt aatccataaa cattgcctga atttcttctt
    19561 ttacggcttt aagagcgtcg gcggtgggtt gtttgtcttt ttggataatg cgctcgaaaa
    19621 tgcgtttcga caggtcgagg gcgggtgcgt cggggcgagt gtcgcccgat gcctgattga
    19681 taagcgtggc tacctcattc atggcggcct gaattttctc ccaaacctcc tggctcatgt
    19741 atacctgctg cgacaggttg tggttgtatt cgtcccgaat ttcctggagc aaccgttgtt
    19801 gaaattccag tacggtggtg ctgctgttgc ccagccgcag cagcagattg tttgggctga
    19861 tacgttccag aaacagcacc atgcgctcgt aggcttgtag gcgaatcgga actacggttt
    19921 cggtataacg ggtttttact tcattacggt ggcggtcggc ttcccgctca agcaagagtt
    19981 tggttgtcag atacataccg tagagcacta agctggccgg gataatcaac ttcagaaaat
    20041 cgctgaaaag ctgcataaag gtggacgaat tgttcacgcg aaaaaaagta attttgatac
    20101 ttatgattga taaaccgatt gtagttcggc ccgaggcccg tcagcaaatt atcgatacgt
    20161 tgcacgccaa caaaattccc ggcgaatacg gcctgcgggt aggtatacgc ggtggcggct
    20221 gtggcgcatc gtggctgctg ggcttcgacc tgcccggtcc caccgacgaa ctatataacg
    20281 ttgatgatgt gcgtgtcatt atcgaccgaa aacatttact ctacgtattg ggggtcgaaa
    20341 tcggctacga accgggcggg ttcacggttg aaaagagtgc aggggagggg gcatagggcg
    20401 aaagatggtc atggtctccg ctttcgcttg tcgtgtcgtt tgcctatcga aattcttggc
    20461 atgattttag gtcatgtttt tttaactttc tcttatgcct tgtgaagcgt atcgaacatc
    20521 acctgttttt agttctggct ctgctggcgg ttgggttgtc ggtactctgt tattttttct
    20581 ttgaaaaaga tctccccgga gcaaccgacg aacaatacct cagtgctgtt caggaacgtg
    20641 taaaagaaga aacccaggtc agtgccaacg aattgaacac gattgcgggc ctggttcaac
    20701 aaaagaaaaa gccaacgttt tctgagttga ccgtggcaac gcgctacccg tattttatat
    20761 tccagaatgg gcagttacta tactggtccg atcatcgatt tattcctgac tatgagcaga
    20821 taaaggccgt agttcagccc caattagtcg atttcaatga aagccgttat ttagtaagtc
    20881 atcgacaact aaagcgtcag acaacggatg tcgatatatt ttcgctgatt ccgatttaca
    20941 aatattacca cagcagtaac gcatacttac aatcgggcta taattctggt attttctcta
    21001 ttgatccaca ggctgtcagc actacccggc aaaaagcgtt tcaggctatc tacgaccact
    21061 catccgtctt tctgttctcg gttgtaccgc ccaaagtcga tatttaccga aatcagtcaa
    21121 ccccggccaa tacggtaatt ctggctacgt tagccgtgat gtttcttggc ttgtacgtac
    21181 tacgcgtact aacgcgcctg aaacgacgtc ggcagtatga gcgcggcttt atctggttgt
    21241 cggcttacct ggttttgttg cgggcgttga tgctctattt cggtgttccg tttctgtttg
    21301 tcgaatcgga tttgttcaat ccgcgttttt atgccgcttc ggtgctggtt ccttccttag
    21361 gcgacttgct cctgaacgcg ctggtggtac tggtgctggc gttatactgg gttaatcatt
    21421 actatcgctc cggggcttat cgattgttgc tcaacatccc caagtgggcg caaaccttgc
    21481 tttcgttggt atgcgttgcg tcaagctatg gcgtattcgc gctgtgctac agggagttaa
    21541 acaacattta cgaaaagtcg cagtttacac tcgacatcac tttgagcatt cagttttcgg
    21601 ccctgaaact ggtgtgtctg ctggtgttca ttgtaatttc ctgcatttat tttctgtcgc
    21661 ttcatttgct cgtcagcctg tttattcggt acaaccgacg ggtgcatctt gggcgtgggt
    21721 tatttctggt agtgctcgga accatgctga caggcgtatt ctgctggctg gcgggctggc
    21781 cggttagctg gattttgctg ctgaatggcg tttattttat gctgacatac gccagtcagc
    21841 tacctcgaac gctgtacaca ttccgctatc gcacgtccat atatttgttt ctggccgctt
    21901 ttgtttgtgc tgccatgact gcttacgtgg tttataatca ggagattaga aaacagttgg
    21961 tgcaggaacg cgaatttgcc cggcaactgc tcgccgaaaa cgacgagttc ggcgaatttc
    22021 tgatgggtaa agcgcaggag tctattgccc gcgaccttga aatcagccgt gcgttacgcg
    22081 tcgattcggt gctggtgcgc gaacggattc agcaacgggt gaagagcctg cacttagata
    22141 agtactttga taagtatgat attgaggtct tttcgttcca ggccaatggt aagccgctcg
    22201 atattagtcc agccgctccg tcgctggcgg tcctgtcgga ccgataccgg caaaaaaact
    22261 acctgaccaa gaaccccaat atttactttg taaacgaagt cggcaatcag tttataaaac
    22321 aatacctctg cttcatcgaa attcggcaaa cagatggctc ggccacctcg ttggggagtt
    22381 cggctggtac tacgctgggc catattgtgc tggatatgcg gctccgtaac gagcggccca
    22441 aaaatgttta tcccgaactg ctggtcgatg ccaaattcag tcagcaaccc aacgcccccg
    22501 aatacagcta cggtgttttc agtggtaaac ggctcggtgg tattcagcta aaatcggagc
    22561 caccttacgg actcatttac agtgcaggca gctacaatta cgaacgtaaa atgaccccgc
    22621 aactgctcga aacagtgatt atgcatacag aaggggtttc ggcgaacggc taccagcacg
    22681 tagcccagcg agggcatgat ggccgggtgg tagtggtgtc ggcagccgag tatccattca
    22741 ggaatgcgtt ctcgaatttc tcgttcctgt atctgttgct ggtgctaacc gtaattctgg
    22801 ttattatcgg ttatgcagct aactaccggc ttacccaatt cagtatcaac tattcgacac
    22861 ggattcagat actgttgaat gtggcttttt ttctgcctct actgctggtt attctcatta
    22921 ttctgggggt tatcagtgcc aactacattg cgaatcagga aaatagctac atcaacaaca
    22981 cccgaaacat tgccgctaat tttctgacat acctcagcga acacatggcg cagaagcgca
    23041 gcaaagcgtc gatggaagaa gagttgggta agatagcccg cgatgccgat atcgacatca
    23101 atttattcga tacgcagggc cagctctaca cgtcgacccg gcccctgatc tacgagagtg
    23161 gctatctgtc gaagcgcatc aaccctgaag cctacgttca tgtcatcgaa gacaaagaaa
    23221 atcaggtgct gctgaatgaa tcgctcggta caaagcagta ccgcacggct tacgctggca
    23281 tcaagtcata cgatggtaaa ctgctcggta ttttgagcat accgtatttc tatgcccgcc
    23341 cagatttaga ccggcaattg atcgaagtaa ttgcctcggc actgagcatt tttaccgcac
    23401 tgttcctatt ctttttggtg ctgtcgtact ttgcctcgaa cattttgacc aagccgctac
    23461 gaatgctgac gcagaaaatc cgcaaaacta acctcgaccg accaaatgat ccgctactgt
    23521 ggcgatctga cgatgaaatt ggtctgctga tacgcgaata caaccggatg ctggtgaaat
    23581 tggaggaaag caagcaggaa ctggcgcaga atgaaaaaca atcggcctgg cgcgaaatgg
    23641 cgaagcaggt ggctcacgaa atcaagaacc cgttaacacc tatgaagttg acgttgcagc
    23701 acctgcaacg gaccttgccg ggtagtaatt cgggcgagac cggtgccaac gatgccgtaa
    23761 cgcgccgggt acagcgcaca tttgattcac tgctcgaaca aatcgataac ctgagcgaca
    23821 ttgccacatc gttctccgat ttcgctaaaa tgccgttgcc aaaaaacgaa gtgtttgaag
    23881 tgacgggcgt tctgaacaaa gctgccgacc tatatgccga cgatcaccga attgtgctca
    23941 gaaggcagat tagccccggc cctgttatgg tcatcggcga ccgacagctc attggccgaa
    24001 tacttacgaa tctgataatc aacgctattc aatctgtccc gcccgaccgt cggcctacta
    24061 tcgacctgcg gctctatacg aaagatgacg aagctcagat agaagtacac gacaatggtg
    24121 cgggtattcc cgaagctatt catacgaaag tatttctgcc caatttcagc accaaacggg
    24181 gcggttctgg tttaggatta gctattgcca agcgaggtat cgaacatgcg ggcggaacaa
    24241 tctggtttga aaccaccgaa ggcgttggca cctcgttttt tgtgtcgctg ccgttatcaa
    24301 cagtcggtga tgccacgaaa ctaccaagcc agaccataac acggtaggat agaaaaaagt
    24361 cagccggtca ggaaacccaa ccggctgaaa ctcatagtct caaacatcac tcaaaaacgt
    24421 gtccgcgagc cattttggct gttcatcagg ggcgaaacgg gggtatcgtc atccagagta
    24481 acgtgtttcc aattttcgcc cgaccgtatg cggttaagct gtgtatgtgt aatgccaaac
    24541 tgtttggcaa tcattttaag ccggttttta tcgttacgaa gcagcttctt aataatcttc
    24601 accttgcttt cggtaagctt atagttgcgt gtttgccgaa gtacgggccg gttcttgagg
    24661 tttgggttgt tccgattgtg ttcgatcatc tcctctttcg taacccag
//
