LOCUS       NZ_LZNS01000001        21083 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7185551
            Orig. end                         :: 7206634
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21083
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="37"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21083
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21083
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11083](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11083)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            1114..1956
                     /locus_tag="STBA_RS31900"
                     /old_locus_tag="STBA_64860"
     CDS             1114..1956
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435044.1"
                     /locus_tag="STBA_RS31900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64860"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_216355998.1"
                     /transl_table=11
                     /translation="MVIDRTGLAEFLRRRRESLQPEDVGLPRGRRRRTDGLRREEVAAL
                     CHMSTDYYARLERERGPQPSEQMIASIAQGLHLSLDERDHLFRLAGHNPPARAAISEHI
                     SPGLLRIFDRLHDTPAEIVTELGETLRQTALGVALTGDTSHYSGPARSIGYRWFTDPAV
                     RQLYAPDDHPFLTRMFASGLREVATLRGPGSRAAHLAGLLLARSEEFRKVWNDHEVGIR
                     PHEVKHFVHPELGALELTCQRLIDPDQAHSLLVYTAIPGSESHEKLQLLPVLGTRARH"
     gene            2373..3317
                     /locus_tag="STBA_RS31905"
                     /old_locus_tag="STBA_64870"
     CDS             2373..3317
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979216.1"
                     /locus_tag="STBA_RS31905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64870"
                     /product="C45 family peptidase"
                     /protein_id="WP_077062497.1"
                     /transl_table=11
                     /translation="MRQQHMTFQAIEVGDGGDGRWAAYARALWREMEGLLTEEGRTPEG
                     ADRVRALFRAHMPELVPVLDRLAGQLDRPEAEAFLTHAALRPFSSACTQIGANGTLLRN
                     YDLRPDQCEGTIVSSCFLRPVIGMQDVLWGLLDGMNDAGLAVSLTWGGRSVYGRGFAIL
                     IVVRYLLETCDTVDEAVGRLRSLPVAVPQNLTLVDPAKAVTVFVGPDMSPTVAPDACAA
                     NHQHLPVTDEQERALRTRERLRAIRAAGADVAAMLKPPLYRSVDEQGSRTLYTARYRPV
                     EGRVTYYWPGESWQQSFSDFAPGSRTVTLGRAS"
     misc_feature    complement(2403..2417)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    2691..2693
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3364..>3830
                     /locus_tag="STBA_RS39125"
                     /pseudo=""
     CDS             3364..>3830
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477235.1"
                     /locus_tag="STBA_RS39125"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGQRLTDQLVDRAQAEGLKPAGEGGPLQQLTKRRLESALGYDKRD
                     AAGRHSGSSRYGTRFKALVTDVGPSGGISAARPGRSLRSEVRQEAAKAAKAAEVCDGGG
                     RDRELTGHQGSDDPGGPGPPGRDVRRQGVPAGDPHDHRQRSWTA"
     gene            4432..5460
                     /gene="argC"
                     /locus_tag="STBA_RS31915"
                     /old_locus_tag="STBA_64890"
     CDS             4432..5460
                     /EC_number="1.2.1.38"
                     /GO_function="GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070401 - NADP+ binding [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526146.1"
                     /locus_tag="STBA_RS31915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64890"
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="WP_077062499.1"
                     /transl_table=11
                     /translation="MAVRAAVAGASGYAGGEILRLLLQHPEAEVGALTGHANAGQALGG
                     LQPQLAPLADRVLQPTSAETLAGHDVVFLALPHGQSGALAEQLGDGPLIIDCGADFRLA
                     DAADWERFYGSPHAGTWPYGLPELPGAREALKGSTRVAVPGCYPTAVTLALFPAYAAGL
                     AEPEAVIVAASGTSGAGRSLKPHLLGTEVMGAMSPYGVGGTHRHTPEMMQNLSAVAGER
                     VTVSFTPTLAPMPRGILATCSARARPGVTAAGLRRAYAEALAGEPFVRLLPEGQWPTTA
                     AVAGSNAVQIQVALDEAAGRVIAISAVDNLTKGTAGGAVQSMNIALGLPEVLGLSTIGV
                     AP"
     gene            5457..6608
                     /gene="argJ"
                     /locus_tag="STBA_RS31920"
                     /old_locus_tag="STBA_64900"
     CDS             5457..6608
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /GO_function="GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1220: bifunctional ornithine"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325166.1"
                     /locus_tag="STBA_RS31920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64900"
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="WP_077062500.1"
                     /transl_table=11
                     /translation="MSVTAAQGFTAAGVAAGIKDSGGPDLALVVNRGPRSAAAGVFTSN
                     RVKAAPVQWSEQVLKGGSVTAVVLNSGGANACTGPLGFQDTHATAERAADVLGLGAAEV
                     AVASTGLIGTRLPMDQLLAGVGTAAEELSAHGGEQAALAIMTTDTVHKTAVVDGDGWRV
                     GGMAKGAGMLAPGLATMLVVLTTDADLEAPALDRALRAATRTTFDRIDSDGCMSTNDMV
                     LLLASGASGVTPEAAVFAEAVRAVCDDLALQLIKDAEGASKDIRIEVVGAASEADALEV
                     GRSIARNNLLKCAIHGEDPNWGRVLSAIGTTSAAFEPDQLNVAINGVWVCKKGALGEDR
                     ALVDMRFREVTITADLAAGAESAVIWTNDLTADYVHENSAYSS"
     gene            6605..7522
                     /gene="argB"
                     /locus_tag="STBA_RS31925"
                     /old_locus_tag="STBA_64910"
     CDS             6605..7522
                     /EC_number="2.7.2.8"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1174: acetylglutamate kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145950.1"
                     /locus_tag="STBA_RS31925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64910"
                     /product="acetylglutamate kinase"
                     /protein_id="WP_077062501.1"
                     /transl_table=11
                     /translation="MTNAPARKHTALPKARILIEALPWLTRHHGKTVVIKFGGNAMVDD
                     ALKAAFAQDVVFLRHAGLRPVVVHGGGPQISAQLDRLGLTSEFRAGLRVTTPETMDVVR
                     MVLAGQVQRELVGLLNRHGPLAVGMTGEDAHLMSAVKRFADIDGERVDIGRVGDITHVD
                     TGAVRALLDDGRVPVISSIARSADDDHVYNINADTAAAALAAALGAETLMVLTDVEGLY
                     ADWPASDEVISRLTESELEKLLPELASGMVPKMEGCLFAVRNGVRTARVIDGRVQHSIL
                     LEIFTDEGIGTMVVPDAAGKGGAA"
     gene            7519..8739
                     /locus_tag="STBA_RS31930"
                     /old_locus_tag="STBA_64920"
     CDS             7519..8739
                     /EC_number="2.6.1.11"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (34-346). E-value: 1.7e-97.
                     Score: 318.4. Matches aSDomain:
                     nrpspksdomains_STBA_RS31930_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018836812.1"
                     /locus_tag="STBA_RS31930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64920"
                     /product="acetylornithine transaminase"
                     /protein_id="WP_077062502.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.7e-106, bitscore:
                     354.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNAPEGKGPGGNAALAARWRGALMDNYGTPRLALTHGEGSRLWD
                     ADGKEYLDFVGGIAVSSLGTGHPAVVRAVSEQVARLGHVSNLYIAEPPVALAERLLGLV
                     GRPGRAFFCNSGAEAVEAAFKIGRRTGRPHMVATEGGFHGRTMGALALTGQPAKQAGFG
                     PLPGDVTHVPYGDAAALRAAVTERTALVIVEPVQGENGVVVPPEGYLAAVRDITHATGS
                     LLVLDEVQTGIGRTGHWFAGQAAGVEPDVVTLAKGLAAGLPIGATLAFGPAADLLAPGG
                     HGSTFGGNPVSCAAALAVLDTIESENLLQRVKEAGERLRDGIWGLGHPLVDRVRGAGLL
                     LGIVLTEPRAPQVQQAAQDAGLLVNAVAPDVLRLAPPLIIGDAEVDAFLTALPGVLDTV
                     DTSTGER"
     aSDomain        7621..8556
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STBA_RS31930_Aminotran_3.1"
                     /evalue="1.70E-97"
                     /label="STBA_RS31930_Aminotran_3.1"
                     /locus_tag="STBA_RS31930"
                     /protein_end="346"
                     /protein_start="34"
                     /score="318.4"
                     /tool="antismash"
                     /translation="LTHGEGSRLWDADGKEYLDFVGGIAVSSLGTGHPAVVRAVSEQVA
                     RLGHVSNLYIAEPPVALAERLLGLVGRPGRAFFCNSGAEAVEAAFKIGRRTGRPHMVAT
                     EGGFHGRTMGALALTGQPAKQAGFGPLPGDVTHVPYGDAAALRAAVTERTALVIVEPVQ
                     GENGVVVPPEGYLAAVRDITHATGSLLVLDEVQTGIGRTGHWFAGQAAGVEPDVVTLAK
                     GLAAGLPIGATLAFGPAADLLAPGGHGSTFGGNPVSCAAALAVLDTIESENLLQRVKEA
                     GERLRDGIWGLGHPLVDRVRGAGLLLGIVLT"
     gene            8756..9334
                     /locus_tag="STBA_RS31935"
                     /old_locus_tag="STBA_64930"
     CDS             8756..9334
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884917.1"
                     /locus_tag="STBA_RS31935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64930"
                     /product="arginine repressor"
                     /protein_id="WP_077062503.1"
                     /transl_table=11
                     /translation="MSQEPQITGSSAAPSAPGPGPAVPQTRAARHRRIVDILNRQPVRS
                     QSQLAKLLADDGLTVTQATLSRDLDELGAVKIRNTGGELIYAVPSEGGYRTPRVPLGES
                     AKEERMARLAGELLISAEASANLVVLRTPPGAAQFLASAIDQAEVHDILGTIAGDDTLL
                     LISRDPVGGQSLADHLLRLAQKQKEQPED"
     gene            <9538..>9696
                     /locus_tag="STBA_RS39130"
                     /pseudo=""
     CDS             9538..>9696
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009063547.1"
                     /locus_tag="STBA_RS39130"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /pseudo=""
                     /sec_met_domain="Aminotran_3 (E-value: 1.6e-08, bitscore:
                     32.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAALRAAVTERTALVIVEPVQGENVVVVLSAGSLLVLDEVRTGI
                     GRTGHWFA"
     gene            complement(10001..11083)
                     /locus_tag="STBA_RS31945"
                     /old_locus_tag="STBA_64950"
     CDS             complement(10001..11083)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435052.1"
                     /locus_tag="STBA_RS31945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64950"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_077062504.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2e-56, bitscore:
                     189.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVPETTGEHHTALGTLRQARELLDPALRTWVHRLPAPVARVAS
                     YHFGWTDSSGRPDSAPAGKALRPALVFGCAEAVGARPEEAVAPAVAVELVHNFSLLHDD
                     ILDGDTTRRHRATAWTVFGNSAALLAGDALLIHAGRVLTEQPAGLATVTGIRWLSEATT
                     QLIEGEHTDISFEERSHVSLAECLAMTERKTAALLACSCALGALWGGGAPERTEALRRF
                     GTHLGMAFQLTDDLLGIWGDPAVTGKPAGADLASRKKSLPVVAALDSGTPAARRLAELY
                     LPDAGAPAAARTEGAAAEDPELTARIAALVEEAGGRSWAEKAAEEELRLALDCLDLARP
                     EGGAGERLAALARLACHRDR"
     gene            complement(<11167..>11441)
                     /locus_tag="STBA_RS36065"
                     /pseudo=""
     CDS             complement(<11167..11441)
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="STBA_RS36065"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MATEAGPFPQGTVKSPVAFGQLLGQGIGDTIRVSLPVPPVEEVKV
                     AIQILESPARGPAGPRSSPAPCPSPSRTVSSTDLARRGKPASASPR"
     misc_feature    complement(11376..11378)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11459..11474
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.53"
                     /tool="antismash"
     gene            complement(11629..12195)
                     /locus_tag="STBA_RS31955"
                     /old_locus_tag="STBA_64960"
     CDS             complement(11629..12195)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544465.1"
                     /locus_tag="STBA_RS31955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64960"
                     /product="GNAT family protein"
                     /protein_id="WP_077062506.1"
                     /transl_table=11
                     /translation="MLTTSLGPEAELCPLEPWQAAEFFAYTDRARAHLAPWLPWTGAVT
                     DTASARRFLQRFADSQAADGPRIYGIRLSGELVGGMIFRLFDAAQGSCELGAWLAPEAQ
                     GRGLVTRAAGAMIDWAVGARGLSRVEWLVSPANGPSIAVAKRLGMTHEGTLRSVFEMDG
                     KRHDLELWAVLEEEWRQRAGSHPHE"
     gene            complement(12259..13089)
                     /locus_tag="STBA_RS31960"
                     /old_locus_tag="STBA_64970"
     CDS             complement(12259..13089)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484305.1"
                     /locus_tag="STBA_RS31960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64970"
                     /product="TIGR02452 family protein"
                     /protein_id="WP_077062507.1"
                     /transl_table=11
                     /translation="MSARLRAIAKETEQIVDAGWYSAPGGGRVEIAAAVARAAAGTELF
                     GPGPVALPDGAAPAGPPRIEVTGESSLDAARRLTTAGRDPVAVLNFASARNPGGGFLNG
                     AQAQEEALCRSSALYACLLRAPEFYAAHRADRDPFYSDRVIHSPAVPVFRDDRGTLLAA
                     PYEVGFLTSAAPNAGVVARRSPERTGELPAVLHRRAERVLRVASAAGYRRLVLGAWGCG
                     VFRNDPAQVAAAFRALLGPGGPFTGRVDEVVFGVLDRQDPSPTRNAFALEFASL"
     misc_feature    13041..13055
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.95"
                     /tool="antismash"
     gene            complement(13124..13510)
                     /locus_tag="STBA_RS31965"
                     /old_locus_tag="STBA_64980"
     CDS             complement(13124..13510)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005319349.1"
                     /locus_tag="STBA_RS31965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64980"
                     /product="VOC family protein"
                     /protein_id="WP_077062508.1"
                     /transl_table=11
                     /translation="MAGEVAFIEFGVADTVRARTFYSALFGWTFTPGPAEGGLLISGLG
                     TPGGVHGADPGAVPYVFFRVEDMDAALEKVRALGGSAENMAVEGDAAEQARFGRFVLCR
                     DDQGSRFGLHQPPPSAAGDESTGP"
     misc_feature    complement(13533..13548)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            complement(13586..14188)
                     /locus_tag="STBA_RS31970"
                     /old_locus_tag="STBA_64990"
     CDS             complement(13586..14188)
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /GO_function="GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524161.1"
                     /locus_tag="STBA_RS31970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_64990"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_077062509.1"
                     /transl_table=11
                     /translation="MGKSYARIAGRLRTFIEEQHIFFTATAPLSGDGTVNLSPKGLTGS
                     LVVLDEQTVAYLDFAGSNAETIAHLRENGRITLMWCAFDGPPNIVRVHGRGEPVFRDDP
                     RFPALVARFSAVDPANHGLRAVVVVTAELIRDTCGYAVPFMAYEGDRGLHASRFARETD
                     ETLDAYFHKKDHIGTSMDGLPGLPLPLPPTPPAPLTD"
     misc_feature    complement(14252..14270)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.21"
                     /tool="antismash"
     gene            14295..15491
                     /locus_tag="STBA_RS31975"
                     /old_locus_tag="STBA_65000"
     CDS             14295..15491
                     /EC_number="6.3.4.5"
                     /GO_function="GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1291: argininosuccinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018836804.1"
                     /locus_tag="STBA_RS31975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_65000"
                     /product="argininosuccinate synthase"
                     /protein_id="WP_077062510.1"
                     /transl_table=11
                     /translation="MTQRVVLAYSGGLDTSVCIGWIAEATGAEVVAVAVDVGQGGESLD
                     VIRKRALACGAVEAEVVDAKDEFAQEYCLPAIRANGLYMDRYPLVSSLSRPVIVKHLVA
                     AARKHGADTVAHGCTGKGNDQVRFEAGIASLAPDLKCIAPVRDYAMTRDKAIAFAEAKG
                     LPIATTKKSPYSIDANVFGRAIETGFLEDIWNGPIEDIYEYTQNPATPRDADEVVVTFE
                     RGVPVAIDGRSVSVLQAVQELNERAGAQGVGRIDMVEDRLVGIKSREVYEAPGAMALIT
                     AHQELESVTVERELARYKRQVEQRWSELVYDGLWFSPLKRALDGFVNEANEHVSGDIRM
                     TLHGGRAVVTGRRSGESLYDFSLATYDTGDTFDQSLAKGFIDIFGLSSKIAARRDLAQ"
     gene            15488..16921
                     /gene="argH"
                     /locus_tag="STBA_RS31980"
                     /old_locus_tag="STBA_65010"
     CDS             15488..16921
                     /EC_number="4.3.2.1"
                     /GO_function="GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /gene="argH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848932.1"
                     /locus_tag="STBA_RS31980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_65010"
                     /product="argininosuccinate lyase"
                     /protein_id="WP_077062511.1"
                     /transl_table=11
                     /translation="MSGDQPEVRLWGGRFAHGPAEALEKLSASVHFDWRLAPYDIEGSR
                     AHARVLHRAGLLTADELDRMLVGLDRLAADVEDGSFTGTIADEDVHTALERGLLERVGP
                     DLGGKLRAGRSRNDQVATLFRMYLREHARIIGGLVADLQEALIGLADAHPDVAMPGRTH
                     FQHAQPVLFAHHVLAHVQALSRDAERLRQWDARTAVSPYGSGALAGSSLGLDPEAVARD
                     LGFEGGSSANSIDGTAARDFVAEFAFITAMIGVDVSRIAEEIIVWNTKEFSFVTLHDAF
                     STGSSIMPQKKNPDIAELARGKSGRLIGNLTGLLATLKALPLAYNRDLQEDKEPVFDSC
                     DQLEILLPAFTGMLATLTVNRERMAELAPAGFSLATDIAEWLVKRGVPFRVAHEVAGEC
                     VKVCEAEGIDLDQLTDEQFAKISPHLTPEVRTVLTVEGALAARDARGGTAPAAVAVQLR
                     DAKGDLGRQRAWAAPPGDS"
     gene            complement(16989..17972)
                     /locus_tag="STBA_RS31985"
                     /old_locus_tag="STBA_65020"
     CDS             complement(16989..17972)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009188297.1"
                     /locus_tag="STBA_RS31985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_65020"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_171987832.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 6.8e-27, bitscore:
                     93.2, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.4e-26,
                     bitscore: 91.5, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAERPVRWGILATGGIAAKLAGDLAEVPGASVVAVASRAPGPAAE
                     FARRFGIPRAYGSWAELAADPEVDVVYVATPHSAHYAAARLCLEAGKAVLCEKPFTLSG
                     AEAKALVDLARERGVFLMEAMWMFCNPVIRRMTELVADGAIGEIRAVHADFGIGGPLDP
                     GHRLLDPALGGGALLDLGVYPVSFAQLLLGEPTEVAAWARLRGGVDENTGMLLGHASGA
                     VAALTCSLVADTARTAAVTGSAGRIEFPRGFFHPERFVLHRQGHEPEEFSGPGPAGSFA
                     HQAAEVMRCLRAGETESPLVPLEGSLAVMRTLDAVRDRIGLRYPGE"
     misc_feature    complement(18165..18180)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            18169..18969
                     /locus_tag="STBA_RS31990"
                     /old_locus_tag="STBA_65030"
     CDS             18169..18969
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (26-123). E-value:
                     4.7e-20. Score: 64.2. Matches aSDomain:
                     nrpspksdomains_STBA_RS31990_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575503.1"
                     /locus_tag="STBA_RS31990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_65030"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_079252513.1"
                     /sec_met_domain="PF00561 (E-value: 6.8e-14, bitscore: 50.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 3.7e-07, bitscore:
                     29.2, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.3e-23, bitscore:
                     81.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITVTLEHTDVRGLPLAYADFGGSGRPVLALHGHFGRARMFAPLA
                     AALAPGHRVIALEQRAHGRSGRDGNVHPDAYLEDAAAFLRGLDAGPAVVLGHSSGGVTA
                     FRLAARYPELVEALIVEDHGALNRQPDIPHPVLDIGDWPRRTGSLAELRRAVESRGIPD
                     ASYFLESATEYPDGWGFLFDLDELMESQRRLVGDWWPDWLGSTCPALLVHGTDSFVLPT
                     AMARAMAERRPGTTLREFPGCGHWVHDDDPDGFADAVAEFLAAL"
     aSDomain        18247..18537
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STBA_RS31990_Abhydrolase_1.1"
                     /evalue="4.70E-20"
                     /label="STBA_RS31990_Abhydrolase_1.1"
                     /locus_tag="STBA_RS31990"
                     /protein_end="123"
                     /protein_start="26"
                     /score="64.2"
                     /tool="antismash"
                     /translation="PVLALHGHFGRARMFAPLAAALAPGHRVIALEQRAHGRSGRDGNV
                     HPDAYLEDAAAFLRGLDAGPAVVLGHSSGGVTAFRLAARYPELVEALIVEDH"
     CDS_motif       18436..18498
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS31990_0001"
                     /evalue="2.30E-06"
                     /label="NRPS-te1"
                     /locus_tag="STBA_RS31990"
                     /protein_end="110"
                     /protein_start="89"
                     /score="20.1"
                     /tool="antismash"
                     /translation="GPAVVLGHSSGGVTAFRLAAR"
     gene            19102..20073
                     /locus_tag="STBA_RS31995"
                     /old_locus_tag="STBA_65040"
     CDS             19102..20073
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435060.1"
                     /locus_tag="STBA_RS31995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_65040"
                     /product="aldo/keto reductase"
                     /protein_id="WP_077062513.1"
                     /transl_table=11
                     /translation="MAFSRYTPTATPAARIGLGLAAVGRPGYINLGRDRDLPAERTPEA
                     LRMRSHQLLDAAYAAGVRYLDAARSYGRAEEFLADWLAARPGVTDVVVGSKWGYTYTAD
                     WRADADVHEVKDHGAATFDRQYAQSRHLLGDRLDLYQIHSVTPDSPALTDPAVLGRLAR
                     LAADGVSVGLSTSGPGQADAVRAALEVTVDGHPLFSTVQSTFNVLEQSAGPALAEAHEA
                     GLTVIVKEAMANGRLAGAAAPPELREIADACGTGPDAVALAAVLGRPWAGIVLSGAATA
                     AQLATNLAAAGLEPDGSRLSALTRLAEPPAVYWRQRAELPWV"
     gene            complement(20078..20758)
                     /locus_tag="STBA_RS32000"
                     /old_locus_tag="STBA_65050"
     CDS             complement(20078..20758)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905432.1"
                     /locus_tag="STBA_RS32000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_65050"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_077062514.1"
                     /transl_table=11
                     /translation="MSRFVLLKVLLGPLLKLFFRPQVEGIRQIPADGPVILAGNHLTFI
                     DSIILPLVMERQVFFIGKDEYVKGRSPRGRLMAWFFTAVGMIPVDRDGGHGGVAALMTG
                     RRVLEEGRVFGIYPEGTRSPDGRLYRGRTGIARLTLMTGAPVVPFAMIGTDRVQPGGRG
                     LPRVGRGRRITVRFGRPLDFSRYEGMDRDRYVLRAVTDEVMTEVMRLSGQEYVDMYATK
                     VKAA"
ORIGIN
        1 gatctgccag atgcgccggg cgttctcggc gccgcgaagg cgggagtaga gcttctgctc
       61 ggccggacgg cccctgaggt gcccgggccc gttcggcccg tagagtcggg cgccctgggc
      121 gtcggcagcc gtcgcggcgt agagggccgg gagttgcgcg gtcccgacgc tcccgacgag
      181 gatgccgcgg gcggacatgg cgcggatcat tctgccgccc aaggtggctc ggtcgcggcc
      241 gacctccggg cgagcggcga gcagattcgt cggagcgatc cccggatggg agaggttgct
      301 cgtgatgccc cagccgcctg cctgactgcg ccggtcgagt tcgaggccga acagtccgaa
      361 cgcgatcttc gactgactgt aggcgcgcct gccgtggtac gagcgttccc agttcaggtc
      421 gtcccagttg atggcattct ggttcgccgc gacgctgatc tgcgaggtca cgcgcgcgtg
      481 gccggcgcgg agcagcggca gcacgtgggc caccagggcg aagtggccga ggtggttggt
      541 gccgaactga agctcgaacc cgtcggtggt cgtctgccgg tcgggaggcg tcatgacgcc
      601 ggcgttgttg atgaggacgt gaatggggcg cccttcctct cgcagggtct cgccgagggc
      661 cgcgacggag tcgagcgagg acaggtcgag ggaccggagc gacacgttcg cgtgggaaac
      721 cgtctgcctg atgtgcgcga ccgccgcctc gcccttgcgt ggattccgga cgggcagaag
      781 cacctcggcc ccggccgcgg cgagccgcgt ggcgagcccg aggccgacac cgtcgctggc
      841 tccggtcacc acggcgcgct tcccggaaag gccgggaacg gtgatgtcga tgggtgcgcg
      901 tggcatgcgt tcactcctcg cagttgggtg gttggctcca cggtcgcgga aaacggcgac
      961 tttattcagg gccgctcgat ccactgatac ggaaggccgg tgccgcttgg tccgttggcc
     1021 acgcagccgt gcggagccgg gaagggggga tcggtgagcc gtggatgccg ggatgcgcgg
     1081 acggtaggaa tgacgcaacg agggaggcaa cgcatggtga tcgatcggac aggactggcg
     1141 gagttcctgc ggcgccgccg ggagtcgctg caacccgagg acgtcggcct cccgcgcgga
     1201 cgacgccgcc ggaccgatgg gctgcggcgg gaagaggtgg cggcgctctg ccacatgtcg
     1261 accgactact acgcgcgact cgagcgggag cgcggccctc agccatccga gcagatgatc
     1321 gcctccatcg cgcagggact ccacctctcg ctcgacgaac gcgaccacct gttccggctc
     1381 gccgggcaca acccgcccgc gcgtgccgcg atcagtgaac acatcagtcc cggcctgctg
     1441 cgcatcttcg accgcctgca cgacacgccc gccgagatcg tcaccgaact cggcgagacc
     1501 ctgcggcaga ccgcgctcgg cgtcgcgctc accggcgaca cgtcccacta cagcggcccg
     1561 gcccgcagca tcggctaccg gtggttcacc gaccccgccg tacggcagct ctacgctccc
     1621 gacgaccatc cgttcctcac ccgcatgttt gcctcgggcc tgcgcgaggt ggccaccctg
     1681 cgggggcctg gttcccgcgc ggcgcacctc gccggcctgc ttctcgcccg cagcgaagag
     1741 ttcaggaagg tgtggaacga ccacgaggtc ggcattcgtc cccacgaggt gaagcacttc
     1801 gtccaccccg agctgggcgc actggagctg acctgtcagc ggttgatcga tccggaccag
     1861 gcccattcgc tgctcgtcta caccgcgatt cccggcagcg agagccacga gaagctacaa
     1921 ctgctgccgg ttctcggaac gcgggccagg cactgatcgc ctcgtggccc tcgcggctca
     1981 ccgcagcggc actgggctga gccggggcag caatccggta cggctccccg tcccggaacg
     2041 tcgcacccgg ctccggccga ggcggggccg ccggccggcc atcgagcggt gagaccgagc
     2101 gcttcacctg gcggatgagc gctcgagttg gcgaggctga gcggctgtgg tggcgggcag
     2161 cgatcctgtg tcgattgcgc gcccccgcct tcttgatgca cggcttctcc aacgcgggat
     2221 attaccgccc acttggaatc ggccacgctc gctttcggcg gcttcgccag atccggcgcc
     2281 tggccgtcgc cgatggcggc cacctggtga ttgcctgccc aattggctag gttgccctcg
     2341 cctcgtccga ttctcacagg ggagtggcag ctatgcggca acagcacatg accttccagg
     2401 cgatcgaggt cggtgacggc ggcgacgggc ggtgggccgc ctacgcccgg gccctgtggc
     2461 gggagatgga gggcctgctg accgaggagg gccggactcc ggagggcgcg gatcgtgttc
     2521 gggcgctgtt ccgtgcgcac atgccggaac tcgtcccggt tctggaccgt ctggccggcc
     2581 aactcgaccg gcccgaggcg gaagccttcc tcacccacgc ggcactgcgg ccgttctcct
     2641 cggcctgcac ccagatcggc gcgaacggca ctctgctgcg caactacgac ttacggcccg
     2701 atcagtgcga gggcaccatc gtctcctcct gcttcctgcg ccccgtgatc gggatgcagg
     2761 acgtgctgtg gggcttgctg gacgggatga acgacgccgg tctcgcggtc tcgctcacct
     2821 ggggcggacg ttccgtctac ggacgtggct tcgccattct catcgtggtg cgctacctgc
     2881 tggagacgtg cgacaccgtc gatgaggcgg tcggcaggct gcggtccctg ccggtcgccg
     2941 tcccacagaa cctcaccctt gtcgatcccg cgaaggcggt gacggtgttc gtggggccgg
     3001 atatgtcgcc gacggtggcg cctgatgcct gcgccgccaa tcaccagcac ctgccggtga
     3061 ccgacgagca ggaacgggcc ttgcggacgc gggagcggct gcgcgccatt cgcgccgcgg
     3121 gtgcggacgt ggcggcgatg ctgaagccgc cgctgtaccg atccgtcgac gagcaggggt
     3181 cgagaacgct ctacacagcc cgctaccggc ctgtggaggg ccgtgtgacg tactactggc
     3241 ccggtgagtc ctggcagcag tccttcagcg acttcgcgcc cggatcccgc accgtgacct
     3301 tgggccgggc cagttgagag gctttccgga ctcgatgcgg ctggggctca gccgccgacc
     3361 gcggtgggac agcggttgac cgaccagctc gtcgaccgtg cccaggccga gggtctgaag
     3421 ccggccggtg agggcgggcc gctccagcag ctgaccaagc ggcggctgga gtctgccctc
     3481 ggttacgaca agcgcgacgc ggccggcagg cacagcggga gcagccgtta cggcacgcgt
     3541 ttcaaggctc tggtgaccga tgtcgggccc agtgggggta tcagtgccgc gcgaccggga
     3601 cggtcccttc gatccgaagt tcgtcaagaa gcggcaaaag cggcaaaagc ggcagaagtg
     3661 tgtgacgggg gcggacgaga ccgtgaactc acgggccacc aagggtctga cgacccggga
     3721 ggccccggcc cacctgggcg agatgtacgg cgccaaggtg tcccggcagg cgatccccac
     3781 gatcaccgac aaaggtcatg gacggcatga ccgagtggca gaaccgtccc tcctcaatcc
     3841 cgccgacgaa gtccaaggcc ggcgacacac gccgctcagc caagctcccg aaaccatgca
     3901 ttcggcccgt gacctgtgag taccgcaccc cgggacggtg gcgccgcctc gcccgccagg
     3961 tgaatccacg taccggcacc gacgccgggc cgggaagctg gccagatcct cgaccgggca
     4021 gatcacatcc gctccagccg tcttccagac tgtgatccat cgacgagtcc acccctcccc
     4081 gtctccaggc gtcccgccac cgccggatcg atggcgtacg actccacaag atcgtccaga
     4141 aggcagctat gcgaccacac cgggcgggac gcgccctccg gacgcgaacc agtgacttga
     4201 tggccccagc acagcgcatg aacgcggcac caggcacgat tcgccacgaa accccgtagc
     4261 tgaacgatga ctccgctgcc ctgcccgcca tctcagccgc tcagccctgc caactcgagc
     4321 actcatccgc caggtgaagc gctcagtcac atcgagccgc cggccatcga tcgcccgatt
     4381 gcataaccct gctgagctgc gtatagtcat gccatcaccg aggaggaggc gatggcagtg
     4441 cgcgctgcgg tggcgggagc gagtggctat gcgggagggg agatcctgcg gctgctgctg
     4501 caacaccccg aggccgaggt cggggccctg acgggccatg ccaacgccgg gcaggcgctc
     4561 ggcgggctcc agccccagct ggcgccgctg gccgaccggg tgctccagcc gacctcggcc
     4621 gagaccctgg ccgggcacga cgtcgtcttt ctcgccctgc cgcacggcca gtccggcgcg
     4681 ctcgccgagc agctgggcga cggcccgctg atcatcgact gcggcgccga cttccggctg
     4741 gcggacgccg ccgactggga acggttctac ggctccccgc acgcggggac ctggccctac
     4801 gggctgccgg agctgcccgg ggcccgcgag gcgctcaagg gctccacgcg cgtcgccgtc
     4861 cccgggtgct acccgacggc cgtcaccctg gcgctgttcc ccgcgtacgc cgccggcctc
     4921 gccgagcccg aagccgtgat cgtagcggcc agcggcacct cgggtgccgg ccgttcgctc
     4981 aagccacacc tgctcggcac cgaggtcatg ggggccatga gcccgtacgg cgtcggcggc
     5041 acgcaccggc acacgccgga gatgatgcag aacctgtcgg ccgtggccgg ggagcgcgtg
     5101 accgtttcgt tcacccccac gctcgcgccc atgccccgcg gcattctggc cacgtgttcc
     5161 gcgcgcgcca ggccgggcgt caccgccgcg gggctgcgcc gggcgtacgc cgaggcgctg
     5221 gcgggggagc cgttcgtgcg gctgctgccc gaggggcagt ggcccaccac cgcggccgtc
     5281 gccgggtcca acgccgtgca gatccaggtg gccctggacg aggcggccgg ccgcgtcatc
     5341 gcgatcagcg ccgtggacaa cctcacgaag ggcaccgcgg ggggcgcggt gcagagcatg
     5401 aacatcgccc tcggcctccc cgaggtgctg ggcctttcga cgatcggagt ggcaccgtga
     5461 gtgtgaccgc agcacaggga ttcaccgcgg ccggggtggc cgcgggcatc aaggacagcg
     5521 ggggtccgga cctggcgctc gtcgtcaacc ggggtccgcg gtccgccgcc gccggggtct
     5581 tcaccagcaa ccgcgtcaag gcggcgccgg tccagtggtc cgagcaggtg ctcaaggggg
     5641 gcagcgtgac ggcggtcgtg ctcaactccg gcggggcgaa cgcctgtacc ggcccactcg
     5701 gcttccagga cacgcatgcc acggcggaac gcgccgccga cgtgctcggg ctcggcgccg
     5761 cggaggtggc cgtcgcctcc accggtctga tcggcacgcg actccccatg gaccagctgc
     5821 tcgccggggt cggcaccgcc gcggaggagc tgtccgccca cggcggggag caggcggccc
     5881 tcgcgatcat gaccaccgac accgtgcaca agacggccgt cgtcgacggc gacggctggc
     5941 gcgtcggcgg catggccaag ggggcgggca tgctcgcgcc cggcctggcg accatgctcg
     6001 tcgtgctcac cacggacgcc gacctggagg cgcccgcgct ggaccgcgcg ctgcgcgcgg
     6061 cgacccgcac caccttcgac cgcatcgact ccgacggctg catgtccacc aacgacatgg
     6121 tgctgctcct cgcctcgggc gcctcgggcg tcacgccgga ggcggccgtg ttcgccgagg
     6181 ccgtccgcgc ggtctgcgac gacctcgcgt tgcagctcat caaggacgcc gagggcgcgt
     6241 ccaaggacat ccgcatcgag gtcgtggggg cggcgagcga ggccgacgcg ctggaggtgg
     6301 ggcgttccat cgcacgcaac aaccttctga agtgcgccat tcacggcgag gaccccaact
     6361 ggggccgggt gctctccgcc atcggcacca cctccgccgc cttcgagccc gaccagctca
     6421 acgtggcgat caacggcgtg tgggtgtgca agaagggtgc gctcggggag gaccgcgcgc
     6481 tggtcgacat gcggttccgc gaggtcacca tcaccgcgga cctcgcggcg ggggccgagt
     6541 ccgccgtcat ctggaccaac gacctcaccg ccgactacgt ccacgagaac agcgcctact
     6601 cctcatgacc aacgcccccg cccgcaagca caccgcgctg cccaaggcac gcatcctcat
     6661 cgaggctttg ccctggctga cccgccacca cggcaagacg gtcgtcatca agttcggcgg
     6721 caacgcgatg gtcgacgacg cgctcaaggc cgcgttcgcc caggacgtcg tcttcctcag
     6781 gcacgccggc ctccgccccg tcgtcgtgca cggcggcggc ccccagatca gcgcccagct
     6841 cgaccggctc ggcctcacct ccgagttccg tgccgggctg cgcgtgacca cccccgagac
     6901 catggacgtg gtccggatgg tcctggccgg gcaggtccag cgggagctgg tcggcctgct
     6961 caaccggcac ggcccgctgg ccgtcggcat gacgggcgag gacgcccacc tgatgtccgc
     7021 cgtcaagcgc ttcgccgaca tcgacggcga acgggtcgac atcggccgcg tcggcgacat
     7081 cacgcacgtg gacaccggcg ccgtgcgcgc gctgctcgac gacggccgcg tcccggtcat
     7141 ctcctcgatc gcacgcagcg cggacgacga ccacgtctac aacatcaacg ccgacaccgc
     7201 cgccgccgcg ctggccgccg cgctcggcgc ggagacgctg atggtgctga ccgacgtcga
     7261 gggcctgtac gcggactggc ccgcgagcga cgaggtcatc agccggctca ccgagagcga
     7321 gctggagaag ctgctccccg agctggccag cggcatggtg ccgaagatgg agggctgcct
     7381 gttcgccgtg cggaacggcg tgcgcaccgc gcgggtcatc gacgggcggg tacagcactc
     7441 catcctgctg gagatcttca cggacgaggg aatcgggacc atggtcgtgc ccgacgcggc
     7501 cggtaaggga ggggcggcat gagcaacgca ccggaaggca aggggcccgg gggcaacgcg
     7561 gcgctcgcgg cgcgctggcg gggtgccctg atggacaact acgggactcc gcgcctcgcg
     7621 ctcacccacg gcgagggctc ccggctgtgg gacgccgacg gcaaggagta cctggacttc
     7681 gtcgggggca tcgctgtcag ctccctgggc accggccacc cggccgtcgt gcgggccgtg
     7741 tccgagcagg tcgcacgcct cgggcacgtc tccaacctct acatcgccga gccgcccgtc
     7801 gccctggccg aacggctgct cggcctggtc ggccggccgg gccgagcctt cttctgcaac
     7861 tcgggcgccg aggccgtcga ggccgcgttc aagatcggcc gccgcacggg gcgtccgcac
     7921 atggtcgcca ccgagggcgg cttccacggc cggaccatgg gcgccctcgc cctgaccggc
     7981 cagcccgcga agcaggcggg tttcggcccg ctgcccggcg atgtcacgca cgtgccctac
     8041 ggcgacgccg cggcgctgcg cgccgcggtc accgagcgga ccgcgctggt catcgtcgag
     8101 ccggtccagg gcgagaacgg cgtggtggtc ccgccggagg gctatctcgc cgcggtccgc
     8161 gacatcaccc acgccaccgg gagcctgctc gttctcgacg aggtgcagac gggcatcggc
     8221 cggacgggac actggttcgc cgggcaggcg gcgggtgtcg agcccgatgt ggtgaccctc
     8281 gccaagggcc tcgcggccgg cctgcccatc ggcgcgactc ttgcgttcgg cccggctgcc
     8341 gacctgctcg cgccgggcgg gcacggctcc accttcggcg gcaacccggt ctcctgcgcg
     8401 gcggcgctcg ccgtgctgga caccatcgag tcggagaacc tgctccagcg cgtcaaggag
     8461 gcgggggagc ggctccgcga cggtatttgg ggcctcggcc acccgctggt cgaccgcgtc
     8521 aggggcgccg gactgctcct cggtatcgtg ctcaccgagc cacgtgcacc gcaggtgcag
     8581 caggcggctc aggacgccgg tctcctggtg aacgccgtcg ctcccgacgt actgcggctc
     8641 gcgccgccgc tgatcatcgg tgacgcggag gtggacgcgt tcctcacggc tctgcccggc
     8701 gttctcgaca ccgtggacac gtcaaccgga gagcgatgac caccggagag agcgcatgag
     8761 ccaggagccg cagatcacgg ggtcgtcggc ggccccctcc gcccccgggc ccgggcccgc
     8821 cgtgccccag acccgcgcgg ccaggcaccg ccgcatcgtc gacatcctca accggcagcc
     8881 ggtgaggtcc cagagccagc tggccaagct gctcgccgac gacgggctga ccgtcaccca
     8941 ggcgacgctc agccgtgacc tcgacgaact gggcgcggtg aagatccgca acaccggcgg
     9001 cgagctgatc tacgccgtgc caagcgaggg cggctaccgc accccccgtg tgccgctggg
     9061 ggagtcggcc aaggaggaac ggatggccag gctcgccggg gaactgctga tctcggccga
     9121 ggcatcggcc aacctggtcg tgctgcggac accgcccggc gccgcccagt ttctcgcctc
     9181 ggcgatcgac caggcggagg tccacgacat cctcggcacg atcgccgggg acgacaccct
     9241 gctgctgatc agccgcgacc cggtgggcgg ccagtccctg gcggaccacc tgctgcggct
     9301 ggcacagaag cagaaggagc agccggagga ctgaccccgg cgggccgccg gggcggacgc
     9361 cgcctccgcc gcccggtcga ttcagccggg catcccgggc tccggcgcgg gaggcggctt
     9421 tgaacgggcg gcgccgttcg aggggttgac cgggccggtc accgctggca gcccgcgccc
     9481 ggccgtcccc gcgacctcgc cgacggggcc gggggcggtc cgcgaaagcc gggcaacgac
     9541 gccgcggcgc tgcgcgccgc ggtcaccgag cggaccgcgc tggtcatcgt cgagcccgtc
     9601 cagggcgaga acgtcgtggt ggtcttgtcc gccggcagcc tgctcgttct cgacgaggtg
     9661 cggacgggca tcggccggac gggacactgg ttcgcccccg gccgggtccg ggggccgcac
     9721 ggaacgcggc cgaccgggcc tgccgacgaa cgcggtgtcg taccccgcgc tggcgaaccg
     9781 ttccgccgtc gccagcgcgg ggcagagcgc gtgcacgacg gtgtcggccg ggacgggacg
     9841 gcgaccgggt cctccggcac gttcgcgact gccgccgcac cgacaccggc ggcccgtgcc
     9901 ggtccagcac ctgctcgacc ggccgggcgg cccgctcgat ccgggcgcgg agccgtgcgg
     9961 cgccgcgtgg agcgccttcc cccctcgtgt ctccgtcctc tcagcggtcc cggtggcagg
    10021 ccagccgggc gagcgccgcg agccgctcgc ccgcgccgcc ctccgggcgg gcgaggtcga
    10081 ggcagtcgag ggcgagacgc agctcctcct cggccgcctt ctccgcccag gaccggccgc
    10141 ccgcctcctc caccagggcc gcgatgcgcg ccgtcagctc cgggtcctcc gccgcggccc
    10201 cctccgtccg cgcggccgcg ggcgcgccgg cgtccggcag gtacagctcg gcgagccgcc
    10261 gcgccgcggg ggtgcccgaa tcgagggcgg ccaccacggg cagcgacttc ttccggctgg
    10321 ccaggtcggc gccggccggc ttgccggtga ccgccggatc gccccagatg ccgagcaggt
    10381 cgtcggtgag ctgaaaggcc atgcccaggt gcgtgccgaa gcggcgcagc gcctccgtcc
    10441 gctcgggtgc cccaccgccc cacagcgcgc cgagtgcgca cgaacaggcc agcagcgcgg
    10501 ccgtcttgcg ctccgtcatg gccaggcatt cggcgagcga cacgtgggac cgctcctcga
    10561 agctgatgtc ggtgtgctcg ccctcgatca gctgcgtggt ggcctcgctg agccagcgga
    10621 tgccggtgac ggtggccagg ccggcgggct gctcggtcag cacccggccc gcgtggatga
    10681 ggagggcgtc cccggccagg agcgcggccg agttgccgaa caccgtccag gccgtggccc
    10741 ggtggcggcg cgtggtgtcg ccgtcgagga tgtcgtcgtg caggagcgag aaattgtgca
    10801 ccagctcgac ggcgacggcg ggcgcgaccg cctcctccgg gcgggcgccc accgcctcgg
    10861 cgcagccgaa caccagcgcc ggccgcaggg ccttgcccgc gggcgcgctg tccggccggc
    10921 ccgagctgtc cgtccacccg aagtggtagg acgcgacccg ggcgacgggg gcgggcaggc
    10981 ggtgcaccca tgtgcgcagc gccgggtcga gcagctcacg cgcttggcgc agggtgccga
    11041 gggcggtgtg gtgctccccc gtggtttcgg ggacggtggt catggcaggg cctccgctga
    11101 ctcgggtgct tgggcttgct cggtgagggc cggggcctcc tcggccaggg ccttcgggac
    11161 ggccttgccc gaggagacgc cgaggccggc ttcccgcgcc tggccaggtc cgttgacgac
    11221 acggtccgtg acggcgacgg gcaaggggcg ggagacgatc tcggacccgc ggggccgcgg
    11281 gccggggact ccaggatctg gatggcgacc tttacctcct ccacgggcgg gacgggcagg
    11341 gagacccgga ttgtgtcccc gatgccctgc ccgagtaact gcccaaacgc gacaggggac
    11401 ttgacggttc cctgtgggaa cgggcccgcc tcggtcgctc ccttcctcgt accgatcgct
    11461 gatcatgtgg tcagcttggc cggtggagag gagcgcagga aggcgtaccg ggaaatcgct
    11521 gcacgccccg ttgtgccaac cgcacgcctc ctttcggtgg gtcagccatg ctgaccagga
    11581 gttccgctca ggccaaaggc cccgctgctg cgcggggccc cggcgtaatc actcgtgtgg
    11641 gtgagagccc gcacgctgcc gccattcctc ctccagcacg gcccacaact ccagatcgtg
    11701 ccgcttgccg tccatctcga acacgctgcg cagcgtgccc tcgtgcgtca tgccgagccg
    11761 cttggccacc gcaatgctcg gcccgttggc cgggctgacc agccactcga cccgcgacag
    11821 gccacgcgcg ccgaccgccc agtcgatcat ggccccggcc gccctggtca cgagcccgcg
    11881 gccctgtgcc tcgggcgcca gccaggcgcc cagttcgcag gagccctggg cggcgtcgaa
    11941 gagccggaag atcatgccgc cgaccagctc gcccgacagc cgtatcccgt agatccgcgg
    12001 gccgtcggcc gcctggctgt cggcgaagcg ctggaggaaa cgccgggccg atgcggtgtc
    12061 cgtgaccgcc ccggtccacg gcagccacgg cgccaggtgc gcccgcgccc ggtcggtgta
    12121 ggcgaagaac tcggccgcct gccagggttc gagcgggcac agttcggctt ccggcccgag
    12181 ggaagtggtg agcacagtgc gcatcctccg tttcggtgcg ctcgtcgcgg ccgccgtcgg
    12241 ccggacgagg cgatcaccct agagggaagc gaactccaag gcgaaggcgt ttctggtcgg
    12301 ggaggggtcc tgccggtcga gcacgccgaa gaccacctcg tccacccgcc cggtgaacgg
    12361 gccgccgggc ccgaggaggg cgcggaacgc cgcggcgacc tgggccggat cgttgcggaa
    12421 cacgccgcac ccccaggcgc cgagcaccag gcgccggtag cccgccgcgg aggcgacccg
    12481 gaggacccgt tcggcacgcc ggtgcagcac cgccggcagc tcgcccgtgc gctccggcga
    12541 acgccgcgcc acgaccccgg cgttgggcgc ggccgaggtc aggaagccca cctcgtacgg
    12601 ggcggcgagc agcgttccgc ggtcgtcgcg gaagaccggt acggcagggg agtggatcac
    12661 gcggtcgctg tagaacgggt cgcggtccgc ccggtgggcc gcgtagaact cgggggcgcg
    12721 cagcagacag gcatacagcg cggacgaacg gcacagcgcc tcctcctgcg cctgtgcgcc
    12781 gttgaggaat ccgccgcccg ggttgcgggc cgaggcgaag ttgagcacgg cgaccgggtc
    12841 gcggccggcc gtggtcagcc gccgggcggc gtccagactg ctctcgcccg tcacctcgat
    12901 gcggggcggc cccgccgggg cggcgccgtc cggcagggca accgggccgg ggccgaacag
    12961 ctcggtgccc gccgcggccc gcgccacggc cgcggcaatc tccacccgcc cgccgcccgg
    13021 cgccgagtac cacccggcgt cgacgatctg ttccgtttcc ttcgcgatgg cacgcagtcg
    13081 tgcgctcacc tcttccccct tccccttccc ttcaccggca gcctcacggc ccggtggact
    13141 cgtccccggc cgcggacggc ggcggctggt gcagcccgaa cctggacccc tggtcgtcgc
    13201 ggcacaggac gaatcggccg aatcttgcct gttccgcggc atcgccctcg acggccatgt
    13261 tctccgcgga acccccgagc gcgcgaacct tttccagggc cgcgtccatg tcctcgaccc
    13321 ggaagaagac gtagggcacc gcgcccgggt cggcgccgtg gacgccaccg ggggtgccga
    13381 gcccggagat cagcaggccg ccctcggcag ggccgggcgt gaaggtccag ccgaacagcg
    13441 ccgagtagaa ggtccgcgcg cggacggtgt ccgccacgcc gaactcgatg aacgcaacct
    13501 cgcccgccat gcgggccccc tttcaccagc ggtatgacgc aggtcacagt agcggggcgg
    13561 cgcgcggctg ccgggcgtgg cgcggtcagt cggtgagggg cgcgggcggg gtcgggggca
    13621 gcggcagggg cagtcccggg agcccgtcca tgctcgtgcc gatgtggtcc ttcttgtgga
    13681 agtacgcgtc gagcgtctcg tccgtctcgc gggcgaaccg ggaggcgtgc aggccgcggt
    13741 ccccctcgta ggccatgaac ggcacggcgt aaccgcaggt gtcccggatc agctccgcgg
    13801 tgacgacgac cacggcccgc agcccgtggt tcgccgggtc gacggcggag aagcgcgcca
    13861 ccagggcggg gaagcgcggg tcgtcgcgga agaccggctc gccgcgcccg tgcacccgca
    13921 cgatgttcgg cggcccgtcg aaggcgcacc acatgagagt gatgcggccg ttctcccgca
    13981 gatgggcgat ggtctcggcg ttgcttcccg cgaagtcgag gtaggcgacg gtctgctcgt
    14041 cgaggaccac gagggagccg gtcaggccct tcggtgacag gttgacggtg ccgtcgcccg
    14101 agagtggggc ggtcgcggtg aagaagatgt gctgttcctc gatgaacgtc ctcaggcggc
    14161 cggctatgcg tgcgtacgac ttacccatgg ggtgagtatc ccccgccggg gacggccggt
    14221 accggacgaa ttgacgaacc atgcggagcc ctgcatactt attccagtca gcgcatgcat
    14281 cataaggaga caccgtgacc cagcgcgtcg tgctcgccta ttccggcggc ctggacacct
    14341 ctgtctgcat cggctggatc gccgaggcaa ccggggcgga ggtcgtcgcc gtcgccgtcg
    14401 atgtcggcca gggcggcgaa agcctggatg tcatccgcaa gcgcgcactc gcctgcggcg
    14461 cggtcgaggc cgaggtggtg gacgccaagg acgagttcgc ccaggagtac tgcctcccgg
    14521 cgatcagggc caacggtctc tacatggacc gctacccgct ggtctcctcg ctgtccaggc
    14581 ccgtcatcgt caagcacctg gtcgccgccg cccgcaagca cggcgccgac accgtggcgc
    14641 acggctgcac cggcaagggc aacgaccagg tgaggttcga ggcgggcatc gcctccctcg
    14701 cccccgacct gaagtgcatc gcccccgtcc gggactacgc gatgacgcgg gacaaggcca
    14761 tcgccttcgc cgaggccaag ggcctgccga tcgccaccac caagaagtcc ccgtactcca
    14821 tcgacgccaa tgtcttcggc cgcgccatcg agaccggctt cctggaggac atctggaacg
    14881 ggccgatcga ggacatctac gagtacacac aaaatccggc gacccccagg gacgccgacg
    14941 aggtggtcgt caccttcgag cgcggcgttc ccgtggccat cgacggcagg tcggtcagcg
    15001 tgctccaggc cgtccaggag ctgaacgagc gggccggtgc gcagggcgtg ggccggatcg
    15061 acatggtcga ggaccggctg gtgggcatca agtcccgcga ggtctacgag gcgccgggcg
    15121 ccatggcgct gatcaccgcc caccaggagc tggagagcgt cacggtcgag cgcgagctgg
    15181 cccgctacaa acggcaggtc gagcagcggt ggtccgagct ggtctacgac ggcctgtggt
    15241 tctctccgct caagcgcgcg ctcgacggct tcgtcaacga ggcgaacgag cacgtcagcg
    15301 gcgacatccg gatgacgctg cacggcggca gggccgtcgt caccggccgt cggtccgggg
    15361 agtcgctgta cgacttcagc ctggcgacct acgacaccgg cgacaccttc gaccagtcgc
    15421 tggccaaggg attcatcgac atcttcggcc tgtcgagcaa gatcgcggcc cggcgggacc
    15481 tcgcccagtg agcggggacc agcccgaggt caggctgtgg ggcggccggt tcgcgcacgg
    15541 accggccgag gccctggaga agctgagcgc ctccgtccac ttcgactggc ggctcgcgcc
    15601 ctacgacatc gagggctccc gcgcgcacgc ccgtgtgctg caccgggccg gcctgctcac
    15661 cgcggacgag ctggaccgca tgctcgtggg cctggaccgg ctcgccgccg acgtcgagga
    15721 cggctcgttc accggcacca tcgccgacga ggacgtgcac accgccctgg agcgcggcct
    15781 gctcgaacgg gtggggcccg acctgggcgg caagctgcgc gccggccggt cgcgcaacga
    15841 ccaggtcgcc acgctcttcc gcatgtacct gcgggagcac gcgcggatca tcggcggcct
    15901 ggtcgcggat ctccaggagg cgctgatcgg cctcgccgac gcccacccgg acgtcgcgat
    15961 gcccggccgc acccacttcc agcacgcgca gcccgtcctc ttcgcccacc acgtcctggc
    16021 ccacgtccag gccctgtccc gggacgcaga gcggctgcgg cagtgggacg cgcgcaccgc
    16081 cgtctccccc tacggctcgg gcgcgctggc cggctcgtcc ctcgggctcg acccggaggc
    16141 cgtcgcccgg gacctcggct tcgagggcgg ttcctcggcc aactcgatcg acggcacggc
    16201 cgcccgcgac ttcgtcgccg agttcgcgtt catcaccgcc atgatcggcg tggacgtctc
    16261 ccggatcgcc gaggagatca tcgtgtggaa caccaaggag ttctccttcg tgaccctgca
    16321 cgacgcgttc tccaccggca gctcgatcat gccgcagaag aagaacccgg acatcgccga
    16381 gctggcccgc ggcaagtcgg gccgcctcat cggcaacctg accgggctgc tcgccaccct
    16441 caaggcgctg ccgctcgcct acaaccgcga cctccaggag gacaaggagc cggtcttcga
    16501 ctcctgcgac caactggaga tcctgctccc ggcgttcacc ggcatgctcg ccaccctcac
    16561 cgtcaaccgg gagcggatgg cggagctggc cccggccggc ttctcgctcg ccaccgacat
    16621 cgccgaatgg ctggtcaagc gcggcgtgcc gttccgcgtg gcgcacgagg tcgcggggga
    16681 gtgcgtcaag gtctgcgagg cggagggcat cgatctcgac cagctcaccg acgagcagtt
    16741 cgcgaagatc tctccccacc tcacgcccga ggtgcgcacc gtgctgaccg tcgagggcgc
    16801 cctggccgcc cgcgacgccc gcggcggcac cgcacccgcc gccgtggccg ttcagctccg
    16861 cgacgccaag ggcgacctgg gccggcagcg cgcctgggcc gcgccgcccg gcgattcctg
    16921 attcctgagg cggcgcaccg cgagcccgcc ggcaccaccg tgccgaaggg ctcgcggtac
    16981 gccgtccgct actcgccggg gtagcgcagc ccgatgcggt cgcgcacggc atccagcgtg
    17041 cgcatcacgg ccaggctgcc ctccagcggc accagcggcg attccgtctc accggcccgc
    17101 agacagcgca tcacctcggc ggcctggtgc gcgaacgacc cggcgggtcc aggaccggag
    17161 aactcctcgg gctcgtgacc ctggcggtgc agcacgaacc gctcggggtg gaagaagccc
    17221 cgcgggaact cgatgcggcc cgccgagccg gtcaccgccg ccgtcctcgc ggtgtccgcg
    17281 accagcgagc acgtcagcgc cgccaccgcc cccgaggcgt ggccgagcag catcccggtg
    17341 ttctcgtcca ccccgccgcg cagccgggcc cacgccgcca cctcggtcgg ctcccccagc
    17401 agcagctggg cgaaggagac cggatacacc cccagatcga gcagcgcgcc gccgccgagc
    17461 gccgggtcga gcagccggtg ccccgggtcg agcgggccgc cgatgccgaa gtccgcgtgc
    17521 acggcgcgga tctcgccgat ggccccgtcc gccaccagct cggtcatccg ccggatcacc
    17581 gggttgcaga acatccacat ggcttccatc aggaagacgc cgcgctccct ggccaggtcc
    17641 accagggcct tcgcctcggc cccgctcagc gtgaacggct tctcgcacag caccgccttg
    17701 cccgcctcca ggcacagccg cgccgcggcg tagtgcgcgc tgtgcggggt cgccacgtac
    17761 accacgtcga cctcggggtc ggcggcgagc tccgcccaac tgccgtacgc gcgcgggatg
    17821 ccgaaacgcc gggcgaactc cgccgcaggc cccggcgccc gggaggccac cgccaccacc
    17881 gaggcgccgg gcacctccgc gagatcaccg gccagcttgg cggcgatgcc gccggtcgcc
    17941 agaattcccc accgcaccgg gcgctccgcc attcgcactc ctcgttccgg cgccgtgacg
    18001 cgctgtcagg ggccgctctg aaagatgtgc tcatcgtaat cgggccgcgg gggagaggag
    18061 caggcggccg cggcccccgg tgatcttggg ggcgggcggc ggtgggtagt ctcggccctt
    18121 cgcgtcccgg cccttccggc cgggacttcg tcatggatgg agaagatcat gattaccgtc
    18181 accctggagc acaccgacgt ccgcggtctg ccgctggcct acgccgactt cggcgggagc
    18241 ggccgaccgg tgctcgccct gcacgggcac ttcgggcggg ccaggatgtt cgcaccgctg
    18301 gccgccgccc tcgcccccgg ccaccgcgtg atcgcgctcg aacagcgcgc gcacgggcgc
    18361 agcggccggg acgggaacgt tcaccccgac gcctacctgg aggacgccgc cgcgttcctg
    18421 cgcggcctcg acgccggacc ggccgtcgtc ctcggccact cctcgggcgg cgtcacggcg
    18481 ttccgcctgg ccgcccgtta ccccgagctg gtcgaggccc tgatcgtcga ggaccacggg
    18541 gcgctcaacc ggcagcccga catcccccac cccgtcctgg acatcggcga ctggccgcgg
    18601 cgcaccggct cgctcgccga gctgcggcgg gccgtcgagt cccgcggcat ccccgacgcg
    18661 agctacttcc tggagagcgc caccgagtac ccggacggct ggggcttcct gttcgacctg
    18721 gacgagctga tggagtcgca gcgccggctg gtcggcgact ggtggcccga ctggctcggc
    18781 tcgacctgcc ccgcgctcct cgtccacggc accgacagct tcgtgctgcc caccgcgatg
    18841 gcccgcgcca tggccgagcg gcggcccggc accacgctgc gggagttccc cggctgcggt
    18901 cactgggtcc acgacgacga tcccgacgga ttcgccgacg ccgtcgcgga attcctggcc
    18961 gccttgtgag gacaccgcgc ggcacccggc ccggccccgt gccgcgcccg gccgcgcggg
    19021 gcgaccggcc ggtggttacg gtgaaggccg ccccccgtcc cgaggccgcc gccgaggcgg
    19081 catccgcccg aaggtgaccg catggcgttc tcccgctaca cccccaccgc aactccggcc
    19141 gcccgcatcg gactcgggct ggccgccgtc ggccgccccg ggtacatcaa cctcggcagg
    19201 gaccgtgacc tgcccgccga gcgcactcct gaggcgctgc ggatgcgcag ccaccagctg
    19261 ctcgacgccg cctacgcggc cggcgtccgc tacctcgacg cggcccgttc ctacggccgg
    19321 gccgaggagt tcctcgccga ctggctcgcc gcccgccccg gcgtcaccga tgtcgtcgtc
    19381 ggcagcaagt ggggctacac ctacaccgcg gactggcgcg ccgacgccga cgtccacgag
    19441 gtgaaggacc acggcgccgc cacgttcgac cgccagtacg cgcagtcccg ccacctgctc
    19501 ggcgaccggc tcgacctgta ccagatccac tcggtcaccc cggacagccc ggccctcacc
    19561 gacccggccg tgctcggccg gctggcgcgg ctggccgcgg acggggtcag cgtggggctg
    19621 tccaccagcg gtcctggcca ggccgacgcc gtccgcgcgg ccctggaggt cacggtcgac
    19681 ggccatccgc tgttcagcac ggtgcagtcg acgttcaacg tgctcgaaca gtccgcgggg
    19741 cccgcgctgg cggaggcgca cgaggccggt ctcaccgtga tcgtgaaaga ggcgatggcc
    19801 aacggccggc tcgcgggggc ggcggcgccg cccgagctgc gggagatcgc cgacgcgtgc
    19861 ggcaccggac cggacgccgt ggccctcgcg gccgtgctcg gccggccgtg ggcggggatc
    19921 gtgctctccg gggcggccac ggccgcgcag ctggccacca acctcgcggc ggccgggctc
    19981 gagccggacg gttcgcggct gtccgcgctc acccgactgg cggaaccgcc cgccgtctac
    20041 tggcggcagc gcgccgagct gccctgggtc tgagggctca ggccgccttg accttggtgg
    20101 cgtacatgtc cacgtactcc tgcccggaca gccgcatcac ctcggtcatc acctcgtcgg
    20161 tgacggcccg cagaacgtac cggtcgcggt ccatgccctc gtaccgcgag aagtccagcg
    20221 gccggccgaa ccgcaccgtg atccgccgcc cgcggccgac ccgcggcagc ccccgcccgc
    20281 ccggctgtac ccggtccgtg ccgatcatgg cgaacggcac cacgggggcg cccgtcatca
    20341 gcgtgagccg ggcgatcccc gtgcgcccgc ggtacagacg tccgtcgggt gaacgggtgc
    20401 cctcggggta gatcccgaag accctgccct cctccaggac gcgccggccc gtcatcaggg
    20461 cggcgactcc gccgtgcccg ccgtcccggt ccacggggat catgccgacg gccgtgaaga
    20521 accacgccat gaggcgtccc ctgggcgagc ggcccttgac gtactcgtcc ttgccgatga
    20581 agaagacctg ccgctccatg accagcggca ggatgatcga gtcgatgaag gtgaggtggt
    20641 tgccggccag gatcaccggc ccgtcggcgg ggatctgcct gatcccctcg acctgcgggc
    20701 ggaagaacag cttcagcagc gggccgagca gcaccttcag cagcacgaaa cgggacaact
    20761 tcccctccgg tcggtcatgg gcatgcgcgc ctccgcatgc ctagggacca tacccgcgcg
    20821 cgggcataca tcgcgcactg ggtggtcacc gcggatactc aggtttcatg cgccttcgcc
    20881 ggccgtttcc tcgcccgtcc ccgtcaggac agcgccgcgt ccctaccatc gggcgcgatc
    20941 agcgggccgg aagcaagccg cggtccgaaa gaccacgagc cctacggagt gaccatggca
    21001 gctcagcagg cggcaggcgc cgagtcgaga catccgggcc ggcgggccgt gctcggcgtg
    21061 acggcgggcg ccgcgggcgc cgc
//
