LOCUS       NZ_LZNS01000001        22613 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5996940
            Orig. end                         :: 6019553
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22613
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="30"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22613
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22613
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12613](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12613
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            934..1746
                     /locus_tag="STBA_RS27085"
                     /old_locus_tag="STBA_54820"
     CDS             934..1746
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605852.1"
                     /locus_tag="STBA_RS27085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54820"
                     /product="HAD family hydrolase"
                     /protein_id="WP_077063638.1"
                     /transl_table=11
                     /translation="MVASDLDRTLIYSAAALALGMPDAEAPRLTCVEVYRSLPQSFVTE
                     AAGGLLAELAAHPGAFFVPTTTRTREQYLRISLPGPVPRYAICANGGHLLVDGRTDEDW
                     HAAVRRALAADCAPLAEVRDHLRRTADPAWLLRERDAEGLFAYLVVDRGLLPDTWPKEL
                     ADWAAPRGWTVSLQGRKLYAVPRPLTKSAAVAEIARRTGAGTVLAAGDSLLDTDLLLAA
                     DQGWRPGHGELAAAGWAAPHVTALTGQGVACGEEILRAVLRRLDGGAR"
     gene            complement(1748..2365)
                     /locus_tag="STBA_RS27090"
                     /old_locus_tag="STBA_54830"
     CDS             complement(1748..2365)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892234.1"
                     /locus_tag="STBA_RS27090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54830"
                     /product="DUF4383 domain-containing protein"
                     /protein_id="WP_077061710.1"
                     /transl_table=11
                     /translation="MGTYSTSGSPRLPSAGPLALLRRARLDEHLPVDRRLSRVYRIGAG
                     LMGLALVVFGALGLTRNLGMFSTREDTIWGLYTNGALSWLSIVVGLLLFFGMVKGGNLA
                     STLNMLLGVAFVLSGFVNLALLETGANVLNFGMQNVIFSFAAGLLLMSFGMYGRVSGRL
                     PHDNPYWQARHPEARNGAPERQELAERRRKELSERKEFSERK"
     gene            complement(2411..2584)
                     /locus_tag="STBA_RS38035"
                     /old_locus_tag="STBA_54840"
     CDS             complement(2411..2584)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS38035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_54840"
                     /product="hypothetical protein"
                     /protein_id="WP_171987796.1"
                     /transl_table=11
                     /translation="MKAILQPFVEAARAFGHGIKAANAIRHNVTPDRATANATAWTLPR
                     PQAEHARWGPTR"
     gene            2666..3274
                     /locus_tag="STBA_RS27095"
                     /old_locus_tag="STBA_54850"
     CDS             2666..3274
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="STBA_RS27095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54850"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_077061711.1"
                     /transl_table=11
                     /translation="MTTNDQLTPGARRILDVASELFYRRGIHTVGVDTIAAESGVTKRT
                     LYDRFGSKDGLVVSYLETRDRRWRDMITARLDAAQGDPLRRVLVPFEVMPEWLGGSERG
                     CSFINAFAELPEPEHEGRKIIVAEKKWLHTLFHELLTEAGAPDPGTLATQLLSLHEGAI
                     VATAIADAPDAAAAVHAAADALVTAVLGGAGPSSATGPT"
     gene            complement(3258..4598)
                     /locus_tag="STBA_RS27100"
                     /old_locus_tag="STBA_54860"
     CDS             complement(3258..4598)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433082.1"
                     /locus_tag="STBA_RS27100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54860"
                     /product="hypothetical protein"
                     /protein_id="WP_077061712.1"
                     /transl_table=11
                     /translation="MTATRTAKRLAALLLLPPLSVLALAGAALPAAFTGGGTRRWGRGR
                     VEDLRAEAQEAKDAAAAAFYELDTAQRDLRITVETITAADDTRQAARAAADFAAFGERI
                     DQVSQAYITAMDAHDLDAEGLDAGGASRAARELLGARDELARTRQDLERFGQSLGPLLE
                     RAESQLAQVAPAVERARQALRAATEALDAARGAGLGAEDLAASLAALGPELRRLNEGAG
                     QHGIKPTIRRAEDVRRRAESIAADAARLPQRAAEIDRRLFSLRTRAEAIITRAGKVEPV
                     LSELRRRFSVACWQDLQRVPEQAAQSVRQAEQVLTAAQRARDEQRFADATARLTTVHAL
                     LGRTDEAVSAAGERLRRLNEVSFDPRKEIDRTRFVLRDAQRLAMTGRTIPEPRHARPLD
                     AAVERLDRAVATLENGGRNPDYWLFLTELEAVRSAVAAVVDDIRSGR"
     tRNA            4730..4804
                     /anticodon=(pos:6001702..6001704,aa:Val,seq:tac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="STBA_RS27105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="STBA_54870"
                     /product="tRNA-Val"
     gene            4730..4804
                     /locus_tag="STBA_RS27105"
                     /old_locus_tag="STBA_54870"
     gene            <4868..>5032
                     /locus_tag="STBA_RS39035"
                     /pseudo=""
     CDS             4868..>5032
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971496.1"
                     /locus_tag="STBA_RS39035"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="DNA-binding response regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MARVIAAAARPRSSDARDPAREAARKQLSALTERELATARAIADG
                     LGKGNPAVAD"
     misc_feature    5043..5058
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.87"
                     /tool="antismash"
     gene            5159..6214
                     /locus_tag="STBA_RS27115"
                     /old_locus_tag="STBA_54890"
     CDS             5159..6214
                     /EC_number="1.14.19.-"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta12_cd03507"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090516.1"
                     /locus_tag="STBA_RS27115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54890"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_077061713.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 5.2e-14,
                     bitscore: 50.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSTETVSAAAAEPGSAKGSDFARLSRRIAAEGLMRRRPGYYAV
                     RLSLVATAFLGAWVAFALVGDSWWQLAVAAFMALAFGQAALVMHDLAHRQIFSRRRPSE
                     IWGRLFGNLGVGMSYGWWMNKHTRHHANPNHEELDPDVAPDILVWSQEQARAARGIPRF
                     IGRVQGWIFFPLLTLEGFNLHVASFRALRSTPMKRRGLEGVLLTAHVLIYLGVLFTVLS
                     PGKAVAFVLVHQALFGVYLGCCFAPNHKGMPTLKGDDRPDFLRRQVLTSRNVTGSVFKD
                     IALGGLNYQIEHHLFPSMPTPHLRRAAPIVKQYCAEVGVPYHETGLFASWGEAVRHLHT
                     VGVPIRQEPRS"
     gene            complement(6552..6728)
                     /locus_tag="STBA_RS38040"
                     /old_locus_tag="STBA_54900"
     CDS             complement(6552..6728)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS38040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_54900"
                     /product="hypothetical protein"
                     /protein_id="WP_171987797.1"
                     /transl_table=11
                     /translation="MNAQQDHGDRREWADPRYADMVERVYAERRRSKQRSGPRPMRAFM
                     YELPPDRRPPTSD"
     gene            6984..7307
                     /locus_tag="STBA_RS27120"
                     /old_locus_tag="STBA_54910"
     CDS             6984..7307
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS27120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_54910"
                     /product="hypothetical protein"
                     /protein_id="WP_077061714.1"
                     /transl_table=11
                     /translation="MRELTQAVEDQGGPALVDGQGWCEGQFGLRGRGDERKGLVDDTFG
                     DVRPLAPASRPVAAATVARGDHVVIGGETFAVVDMTGGVRDWCITGHDAYHHPVGRAPT
                     RVR"
     gene            7331..8251
                     /locus_tag="STBA_RS27125"
                     /old_locus_tag="STBA_54920"
     CDS             7331..8251
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (56-231). E-value: 3.1e-09.
                     Score: 28.9. Matches aSDomain:
                     nrpspksdomains_STBA_RS27125_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449907.1"
                     /locus_tag="STBA_RS27125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54920"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_253195033.1"
                     /sec_met_domain="adh_short_C2 (E-value: 2e-32, bitscore:
                     111.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTPMCAACCPVGEVPADQIFPALISSAGPPLVAGPMAEHPLTET
                     NVIDTRLEGKNVLVTGGAGNIGAAISRAFAVQGARVAIHYLAQDLPAPEGADWGHITPV
                     PGEAGKLAQELGNGSVAISADLSRPDGARQLAVAAAERLGSIDVLVNNAAHCETPDTVD
                     ALTPDSLERHYRVNTIAPALLIAEAARLRSGDQPLSIVNISTDAARAFPGQIGYGTSKA
                     ALEALTRATALDLAGRGVRVNAVAPGPVQTGWIGEDLIAQATAIVPMGRVGEPEDIADA
                     VVFLASHQARWITGQVLQVAGGHAL"
     aSDomain        7499..8023
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STBA_RS27125_PKS_KR.1"
                     /evalue="3.10E-09"
                     /label="STBA_RS27125_PKS_KR.1"
                     /locus_tag="STBA_RS27125"
                     /protein_end="231"
                     /protein_start="56"
                     /score="28.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VLVTGGAGNIGAAISRAFAVQGARVAIHYLAQDLPAPEGADWGHI
                     TPVPGEAGKLAQELGNGSVAISADLSRPDGARQLAVAAAERLGSIDVLVNNAAHCETPD
                     TVDALTPDSLERHYRVNTIAPALLIAEAARLRSGDQPLSIVNISTDAARAFPGQIGYGT
                     SKAALEALTRAT"
     CDS_motif       7502..7570
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS27125_0001"
                     /evalue="1.20E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="STBA_RS27125"
                     /protein_end="80"
                     /protein_start="57"
                     /score="21.2"
                     /tool="antismash"
                     /translation="LVTGGAGNIGAAISRAFAVQGAR"
     gene            8363..8836
                     /locus_tag="STBA_RS27130"
                     /old_locus_tag="STBA_54930"
     CDS             8363..8836
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982226.1"
                     /locus_tag="STBA_RS27130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54930"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_077061715.1"
                     /transl_table=11
                     /translation="MEARLNLMQIPGAAKFGKQLAAADHTFPRSTVPGTTLELVKIRAS
                     QINGCGFCTDMHTKEAAQAGETSVRLNLIATWREAKVFTGAERAALELTEQGTRIADAA
                     GGVADEVWANAATYYDEDQLAALVCAIALINAFNRLNVLVQQPAGDYQPGQFG"
     misc_feature    9040..9055
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            9100..9900
                     /locus_tag="STBA_RS27135"
                     /old_locus_tag="STBA_54940"
     CDS             9100..9900
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433074.1"
                     /locus_tag="STBA_RS27135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54940"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_253195035.1"
                     /transl_table=11
                     /translation="MNGDSPVVPRTDRPHSARMYDYLLGGRDHYAADSEAADKALASAP
                     TLRIAAQENRKFIARVVRHLVQEVGIRQFLDLGPGLPTSQNVHQVAQEVEPETRVVYVD
                     NDPIVLAFGGAMLEQNERTTVVRGDIRDPLAVLHHPRTREQLDLSRPVGVLAVAVLHFI
                     GDDEDPAGIVRALTGSLAPGSHFVLSHGTADLSAEAAMGVQAAYRSHGVPLTLRSKERF
                     TELFAGLDLIDPGIQVVSEWRATEPPEERPSHADVSWYGGVARL"
     gene            10001..12613
                     /gene="lanKC"
                     /locus_tag="STBA_RS27140"
                     /old_locus_tag="STBA_54950"
     CDS             10001..12613
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569988.1"
                     /locus_tag="STBA_RS27140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54950"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_077061717.1"
                     /sec_met_domain="micKC (E-value: 4.1e-226, bitscore: 751.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.7e-06, bitscore:
                     24.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVFCLVDRHFYEAPERATAQLGGEGHQEGLYETARRAVPQ
                     GWFSERFGDWLHLQPRDAVMPPQGWKVHVSACLDNADKTAAKVWDYCVPRRIPFKFVPA
                     AHLLYLRNSKYAGRHSSGKFVTIYPADEARLRDVLTELGDLLAGEPGPYVLTDLRWGRG
                     PLYVRYGGFVPRFCDDGTGAVVPAIENAEGRLVPDRRGPAFTVPDWVTLPPFLAPHLAA
                     RNGVTLADLPYRIESALHFSNGGGVYRGTDPRTGEAVVLKEARPHAGLAADGADAVTRL
                     QREKDALDLLAGLSVAPAVRDWLTVGDHRFLVMDHVPGRTLNSFFAERHPLLATDPEPA
                     AVADYTRWALTVHGNVERAVAALHGRGLVFNDLHMYNIMVGPDGTSVTLLDFEAAAPAG
                     DGVRQIVAHPGFVAPAGRTGFAIDRYALACLRLALFLPMTTLLAVDPAKAAHLARVAAR
                     EFPDVPGAFFDEAVAEIEGRPGTEVGTPPRAAPPSPGDWPAARDSMARAILASATPERD
                     DRLFPGDIAQFAPGGGLGLAHGAAGVLYALAETGVERYAEGERWLLRHAADPPRNSPLG
                     LYDGLFGVVHALHRLGHTPAALDLASRALGEGWERLPVHLFGGLAGIGLVLDELAADTG
                     NPALAVHAGRAAGLAAERLAAPPEPRGHRRAGLLYGASGAALLFLRRYERTGDERLLAQ
                     AADALRRDLAHCRTDRSGSLLVDEGDRLMPYLGEGSVGIAAVLDDYRAAAFAAGRPAEE
                     DLIQVGRQVLPAARLRYYAQPGLFRGRAGMIWHLSRTGAAGAAAQIEALDWYAMAYRGE
                     LAFPGEQMMRLSMDLATGTAGCLLALGAALHPAGDAGDVPRLPFLPRPRHPQTRPPSA"
     misc_feature    10020..10035
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.63"
                     /tool="antismash"
     misc_feature    12693..12703
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            12697..12837
                     /locus_tag="STBA_RS36805"
                     /old_locus_tag="STBA_54960"
     CDS             12697..12837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471140.1"
                     /locus_tag="STBA_RS36805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54960"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_107485122.1"
                     /transl_table=11
                     /translation="MSLLDLQSMEPETATDGGGGGGGGDISSVSLLICDTHSSNSVILC
                     L"
     misc_feature    12906..12920
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 17.98"
                     /tool="antismash"
     gene            12939..14684
                     /locus_tag="STBA_RS27145"
                     /old_locus_tag="STBA_54970"
     CDS             12939..14684
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142171.1"
                     /locus_tag="STBA_RS27145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54970"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_077061718.1"
                     /transl_table=11
                     /translation="MPQTPAEPTPAEPAPAGPTLRATARHGAARMAVLCLLALAGAGAA
                     LALPAALGRALDLLLTSGDAVTGWSLLSAALICGQAALGAVTTVLTASADARAAAWLRG
                     RLLRRLLAAGPGAADRFPHGDLVTRAGGNAVHAGAAPAALAAAVAAAVTPAGAVVALAL
                     TDPRLALVFLAGLPLLALLLRAFARSAGDAFADYQHCQADIAGRLVDALRGARTIAAAG
                     TERAERRRILAPLPGLGAHGHRMWRVTARATARAALLTPLLTLSVVATGGLLLAAGDLS
                     VGGLLAVARYAALAAGIGLFVGHLNRLVRARAAARRVGEVLAVPPPRYGARTLPADGPG
                     RLECRGVTARRGGREVLRGLDLVVPGGTTVALVGRSGAGKSLLAALAGRLAEPDGGGIL
                     LDGVPLADLDRDALRGAVGYAFERPALVGGTLAGTIGLGPGPAPPPRAHVEAAAVAARA
                     DGFVRMLPEGYATRCADVPLSGGELQRLGLARAFAHGGRLLILDDATSSLDTVTELHVA
                     RALAAHSAARTRLIVAHRAGSAARADLVAWLDDGRIRALGPHRELWRRADYRALWAGEQ
                     VAADA"
     gene            14677..16536
                     /locus_tag="STBA_RS27150"
                     /old_locus_tag="STBA_54980"
     CDS             14677..16536
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483998.1"
                     /locus_tag="STBA_RS27150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54980"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_077061719.1"
                     /transl_table=11
                     /translation="MRDHGAFAFLRRRRRALAALAAWSLLPAAQTFLLGYGLARALDDG
                     FLAGRTGVGLGWLAAAAAGAAAGAFGTGRVHRAVGALAEPLRDQLVREVVARGLHRAVR
                     AGRPDGGTADVSRLTHQVEIARDSFAGLILVLQMFLCTAAGALAGLAWLAPVLLPFVLG
                     PLALALAVFCWSLRPLARRQRAVLVADEALADAFGATVAGLRDVTAAGAEERTAAGVAA
                     RVDAELAAALALGRWGAVRVVAVAIGGHLPVLLLLFLGPWLLRNGVTPGGLLGALTFVT
                     QALLPALQALIGGIGSAGTRLAVVLTRLRGDPLPPDGPPPDGPPRAAPPQDGPSLAAGR
                     RARAPRGNAVELRGVTFAYGGRATPVLDGVDLAVPAGQHLAVVGPSGAGKSTLAALAAG
                     LLAPRAGQVRLCGEPVAGRGAADLAALRVLIPQEAYVFGGSVADNLGCLHPGPPGDAAL
                     LAAVGAVGAEELVDRLGGPGGTVDPAALSAGERQLIALARAFLSTAPVVLLDEATCHLD
                     PAAEARAERAFAARPGGTLVVIAHRISSARRAERALVLDGADLLTGTPRDLLTRSALFR
                     DLAAGWSDPAGAPGDADGVDPVPGAGLAYHRGEVVAHRSLRKP"
     gene            complement(16423..17028)
                     /locus_tag="STBA_RS27155"
                     /old_locus_tag="STBA_54990"
     CDS             complement(16423..17028)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="STBA_RS27155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_54990"
                     /product="response regulator transcription factor"
                     /protein_id="WP_077061720.1"
                     /transl_table=11
                     /translation="MIRLLFVHDDTLLRCALTSLLGAEEDIDVIPASWEEWARMEPHRQ
                     EAVWLVDATCAGFARLADAAAPHRLYDPEDHGLVVLAPAGRPGLLHRAFEARALGYVSK
                     EAAPQRLLDAIRTVAKGGRYVDDALAYDFLSASRMPLTPRELRVLSLAADGAPVPEIAG
                     ELWLAEGTVRNYLAAVIRKTGARNRVDAIRIARGAGWV"
     misc_feature    complement(16534..16536)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17424..18089)
                     /locus_tag="STBA_RS27160"
                     /old_locus_tag="STBA_55000"
     CDS             complement(17424..18089)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556421.1"
                     /locus_tag="STBA_RS27160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_55000"
                     /product="VTT domain-containing protein"
                     /protein_id="WP_077061721.1"
                     /transl_table=11
                     /translation="MQETLGILLYAPWIYVIVAASILLDVFVPLLPSGALVVTAATVAA
                     GAAADVAGLPGPGSADPRLPHLLVLVLCATSASIVGDLLAYRLALRGGRRFDSAIARSR
                     RLSAAHKRLESALVRGGGPLVVLARFAPAGRAVVSLGAGVAQRRTRDFLPWSALAAVVW
                     TGYSVGIGYLGGQLLGASWFSTGLSMVALIAAGAVAVRLLRRAPAKGAAATSTAAPTA"
     misc_feature    complement(18281..18295)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.62"
                     /tool="antismash"
     gene            18287..18865
                     /locus_tag="STBA_RS27165"
                     /old_locus_tag="STBA_55010"
     CDS             18287..18865
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018530858.1"
                     /locus_tag="STBA_RS27165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_55010"
                     /product="superoxide dismutase family protein"
                     /protein_id="WP_077061722.1"
                     /transl_table=11
                     /translation="MKILATGAAAMAAVLATAGAAVAAAGQGDVLLYDAGRFAPVGEAG
                     GEVPKAVTYDEELVPAGSTIHVAQAIRGEAMQIEVAALGLVPGHTYGTHVHTEPCGADP
                     ADAGGHYQDQPGVVDARNEVWLDFTVDAQGVGKAEVGKNWLFRTGGAGSVVLHERATSE
                     GHDEHPPGDAGGRVACFTLPFAGEDAAAR"
     gene            complement(19022..19711)
                     /locus_tag="STBA_RS27170"
                     /old_locus_tag="STBA_55020"
     CDS             complement(19022..19711)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433070.1"
                     /locus_tag="STBA_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_55020"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_079252199.1"
                     /sec_met_domain="HAD_2 (E-value: 1.1e-20, bitscore: 73.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPLTLTARALLLDMDGTLLDSDAVVERVWRSWAEARDVDPARVF
                     AIMHGRQAYATMAELLPERPMAEHRADAARLLARETADTEGVVPIPGAQDFLAAIAAAP
                     HALVTSADTALSDARMAAAGLRMPDVRITAESVSASKPDPEGFLKGAAELGVDPADCLV
                     FEDSAAGIAAARAAGMRVIGVGPRAAALAPTAYAATLEQVRVEAAPRARPEGFPPADGL
                     IRLTVSP"
     misc_feature    complement(19794..19812)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.81"
                     /tool="antismash"
     misc_feature    complement(19796..19809)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.11"
                     /tool="antismash"
     gene            complement(19887..21893)
                     /locus_tag="STBA_RS27175"
                     /old_locus_tag="STBA_55030"
     CDS             complement(19887..21893)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500905.1"
                     /locus_tag="STBA_RS27175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_55030"
                     /product="MDR family MFS transporter"
                     /protein_id="WP_077063640.1"
                     /transl_table=11
                     /translation="MTVRPPPARQSRGTLWLSMSALLLGLFLAALDQTIVATALPTIVG
                     DLGGLDHLSWVVTAYLLAATAGTPLWGKLGDQYGRKRLFQTAVVIFLAGSVLCGLARNM
                     PELIAFRFLQGLGGGGLIVLSMAIVGDLVPPRERGRYQGLFGAVFGATSVLGPLLGGLF
                     VDHLGWRWVFYVNVPVGGVALAVIAAVLHLPARRERHVIDYAGSLLIAAAAGAFVVIAS
                     LGGTTWDWGSWQIAALAVPAAVCLAAFVRVERRAAEPVLPPALFRNRTFTLSCAIAFVV
                     GFALFGGMTYLPTFLQVVHGISPTLSGVHLLPMVLGLLLTSTLSGQLISRTGRWKVFPV
                     LGTAVTAVGLVLLHTLDRDSGNLEMGVCFAVFGMGIGMVLQVLVLAVQNAVPYGDLGVA
                     TSGVTFFRSIGAAFGVAVLGTVFTGRLRDGLHDALGGAELPAGVTVESLLHDPEGLGAL
                     PAAARAAALGAYADAITAVFLYAVPVVVLAHVLAWLLREDPLRESVHAPDLGEAVPPSP
                     VQRSSREECARALSALGSRAGRRDMYRRIAAAAGVDLLPAACWLLLRMARDGSAEPGLL
                     ADRAAVPLDVVTAAARQVEERGLAVRQGLSLVLTDAGRRVADRLAEARENALGELLGDW
                     WGPDRPRDLAELVHDLSRELGGSRAEWPRGGPT"
ORIGIN
        1 caccgaggcc gtcctggccg aacgcgcccg gcccggcggc acccccgtgc tggtctccct
       61 ggcccgtgcg ggcacgcccg tcggggtcct gatgcgccgc tgggcccggc acgcgcacgg
      121 gctcgacctg ccgcactacg ccgtctccat cgtccgcggc cagggcatcg acaccaccgc
      181 cctgcgctgg ctggccgccc atcacgaccc ggccgacgtc gtgttcgtcg acggctggac
      241 cggcaagggc gccatcaccc gggaactggc cgacgcgctg gccccgttcc ccggcttcga
      301 ccccgccctc gcggtgctcg ccgaccccgg cggctgcgtg gccacctacg gcacccgcga
      361 ggacttcctc atcccctcgg cctgcctcaa ctccacggtg tccgggctta tttcgcgtac
      421 cgtgctgcgt tccgacctgg tcggtccgca cgacttccac ggcgccaagc actaccggga
      481 gctggccggc gccgacctct cccgccactt cctggacgtg gtggccggcc ggttcgccga
      541 ggtggccgcg ggcgtggccg ccgacaccgc cgcgctgctc gccgcggacc gcacccccac
      601 ctgggcgggc tggcgcgccg tggaacgcat cagcgccgcc tacggcatcg acaacgtcaa
      661 cctggtcaag cccggcgtcg gcgagaccac ccgcgtgctg ctgcgccgcg ttccctggcg
      721 catcctggcg cgccgcggcg cgggcgccga cctcgaccac atccggctgc tcgccgagca
      781 gcgcggcgtt cccgtcgagg agaccgacga cctgccctac agttgcgtcg ggctcatcca
      841 cccccgttac accaagggcg ccaccggagc cgacggaaag gccgcgcagt gaccgagacc
      901 gcgccgccgc gcgcgagcac gcgcgcgagc accatcgtcg cgagcgacct ggaccgcacc
      961 ctcatctact ccgccgccgc gctcgcgctc ggcatgccgg acgcggaggc gccgcggctg
     1021 acctgcgtcg aggtgtaccg ttcgctgccg cagtcgttcg tcaccgaggc cgcgggcggc
     1081 ctcctggccg aactcgcggc gcaccccggc gcgttcttcg tgcccacgac cacgcgcacc
     1141 cgcgagcagt acctgcggat cagcctgccg gggcccgttc cgcgctatgc gatctgcgcg
     1201 aacggcggcc atctgctggt cgacgggcgc acggacgagg actggcacgc cgcggtgcgc
     1261 cgcgccctgg ccgcggactg cgcgccgctc gcggaggtgc gcgaccatct gcgccgcacc
     1321 gcggacccgg cctggctgct gcgcgagcgc gacgcggagg gcctgttcgc ctacctggtc
     1381 gtcgaccgcg ggctgctgcc cgacacctgg cccaaggagc tggccgactg ggccgctccc
     1441 cgcggctgga ccgtctcgct ccagggccgc aagctgtacg cggtgccgcg cccgctcacc
     1501 aagagcgcgg cggtcgccga gatcgcccgc cgcacggggg ccggcaccgt gctggccgcg
     1561 ggcgattcgc tgctcgacac cgatctgctg ctcgccgccg accagggctg gcggccggga
     1621 cacggcgagc tggccgccgc cggctgggcg gcgccgcacg tcacggcgct gaccgggcag
     1681 ggcgtcgcct gcggggagga gattttgcgg gctgtgctgc gtcggctcga cggcggcgcg
     1741 cgctgagcta cttgcgttcg ctgaactcct tgcgttcgct cagctccttg cgccggcgtt
     1801 ccgcgagttc ctgccgttcc ggcgcgccgt tgcgcgcctc cgggtgcctg gcctgccagt
     1861 acgggttgtc gtgcggcagc cgcccgctga cgcggccgta catgccgaac gacatcagca
     1921 gcaggcccgc ggcgaagctg aagatcacgt tctgcatgcc gaagttgagg acgttggcgc
     1981 cggtctcgag cagcgccagg ttgacgaagc cgctgagcac gaacgcgacc ccgagcagca
     2041 tgttgagcgt cgaggcgagg tttccgccct tgaccatgcc gaagaacagc aggagaccga
     2101 cgacgatcga cagccagctc agcgcgccgt tggtgtacag cccccagatg gtgtcctcgc
     2161 gcgtggagaa catccccagg tttctcgtca ggccgagcgc gccgaagacc acgagcgcga
     2221 gccccatcag acccgccccg atgcggtaga cgcggctgag cctccggtcc accggcaggt
     2281 gctcgtccag gcgggcccgc cgcagcagtg ccagcggtcc tgcgctcggc agccgcggcg
     2341 acccgcttgt gctgtacgta cccatggggg aacctccttc ggccccccgc gtacccgtgc
     2401 aaaacgggct ctaacgcgtc gggccccacc gtgcgtgctc ggcctgcggg cgggggagcg
     2461 tccaggccgt ggcgttcgcg gtggcgcggt ccggggtgac gttgtgccgg atggcgttcg
     2521 cggccttgat gccgtggccg aacgcgcggg ccgcctcgac gaacggttgc aagatcgcct
     2581 tcatggtgtc cctccaggta cactgatctg tgaagttccg tgttccacgg taggtataca
     2641 gatctgtgaa gtcaaggggt gtgccatgac caccaacgat cagctcacgc cgggcgcccg
     2701 gcggattctc gacgtcgcgt ccgagctgtt ctaccggcgc ggcatccaca ccgtcggcgt
     2761 cgacaccatc gccgccgagt caggcgtcac caaacggacc ctgtacgacc gcttcggctc
     2821 caaggacggc ctcgtcgtct cctacctcga aacccgcgac cgccgctggc gcgacatgat
     2881 caccgcccgc ctcgacgccg cgcagggcga cccgctgcgg cgcgtgctgg tgccgttcga
     2941 ggtgatgccc gaatggctcg gcgggtccga gcggggatgc agcttcatca acgccttcgc
     3001 ggagctgccc gagccggaac acgagggacg gaagatcatc gtggccgaga agaagtggct
     3061 gcacacgctg ttccacgagc tgctcaccga ggcgggcgcc ccggaccccg gcaccctcgc
     3121 cacccagctg ctcagcctcc acgaaggcgc catcgtcgcc accgccatcg ccgacgcgcc
     3181 cgacgccgcc gcggccgtcc acgccgccgc ggatgcgctc gtgaccgccg tcctcggcgg
     3241 cgccggcccg tcctcggcta ccggcccgac ctgatgtcgt ccaccaccgc ggccaccgcg
     3301 ctgcgcacgg cctccaactc cgtcaggaac agccagtagt ccgggttgcg gcccccgttc
     3361 tccaacgtgg ccacggcccg gtccagccgc tcgaccgccg cgtccagcgg ccgcgcgtgc
     3421 cgcggctcgg gaatcgtccg ccccgtcatg gccagccgct gcgcgtcccg cagcacgaag
     3481 cgggtcctgt cgatctcctt gcgcggatcg aacgacacct cgttcaatcg ccgcagccgc
     3541 tccccggccg ccgacaccgc ctcgtcggtg cggccgagca gcgcgtgcac cgtcgtcagc
     3601 cgggccgtcg cgtccgcgaa ccgctgctcg tcccgcgccc gctgcgccgc cgtgagcacc
     3661 tgctccgcct gccgcaccga ctgcgccgcc tgctccggca cccgctggag gtcctgccag
     3721 cacgccacgc tgaaccggcg gcgcagctcg ctcagcaccg gctccacctt gccggcgcgc
     3781 gtgatgatcg cctccgcccg cgtccgcagg ctgaacagcc gccggtcgat ctccgccgcc
     3841 cgctgcggca gccgcgccgc gtccgccgcg atcgactcgg cccgccgccg cacgtcctcc
     3901 gcccggcgga tcgtcggctt gatgccgtgc tgccccgccc cctcgttcag ccgccgcaac
     3961 tcaggaccga gcgccgccag cgaagccgcg agatcctccg cgccgagacc ggcgccgcgc
     4021 gccgcgtcca gcgcctccgt cgccgcccgc agcgcctgcc tggcccgctc caccgccggc
     4081 gccacctgcg ccagctgcga ctcggcccgc tcgagcagcg gccccagcga ctgcccgaac
     4141 cgctccagat cctgccgggt gcgcgccagc tcgtcgcgcg cccccagcag ctcccgcgcc
     4201 gcccgcgacg cgcccccggc gtccaggccc tccgcgtcca ggtcgtgcgc gtccatcgcg
     4261 gtgatgtacg cctggctgac ctggtcgatc cgctcgccga acgccgcgaa atccgccgcg
     4321 gcccgcgccg cctgccgtgt gtcgtcggcc gcggtgatcg tctccacggt gatccgcaga
     4381 tcccgctgcg cggtgtcaag ctcgtagaac gcggcagccg cggcgtcctt cgcctcctgc
     4441 gcctccgccc gcagatcctc cacccgcccc cgcccccacc ggcgcgtccc cccaccggtg
     4501 aaagccgcgg gcagcgcggc acccgcgagg gccagcacgg acagcggcgg aagcagcagg
     4561 agtgcggcaa gccgtttcgc ggtgcgcgtc gctgtcacgt gtcccactcc ccgccggtgg
     4621 attggccatg tgagtaccac ggccattctc ccaccagcct cacgaagcgg gggcaacccg
     4681 gcgtttactg cacgccacgg acggccgtgt aggctgtggc cccgatccag ggtgcatagc
     4741 tcagcggtag agcgccgccc ttacaaggcg gatgtcggcg gttcgaaccc gtctgcaccc
     4801 accaggcagt atgtcgcctg ccggcactct ggcgtgcggt aagagtccac acagggtcca
     4861 catccccacg gcgcgggtga tcgccgcggc ggctcggccg cggtcctccg acgctcgcga
     4921 cccggcccgc gaagccgcgc ggaaacagct gtccgcactg accgaacggg aactcgccac
     4981 cgcccgggcc atcgcggacg ggcttggcaa gggcaacccg gcggtcgcgg accgggtgcg
     5041 gatcgcactc ctgttccatg gtgtacccag catcacctgc atcagggggt gcaggccccc
     5101 atgagggcgg ggggcaggcg gctgtcccgc cggcgccggg ggccgaagac ttggcggcat
     5161 gacgacgagc acggagacgg tgtccgcagc ggctgctgaa ccggggagtg cgaaaggcag
     5221 tgacttcgcc cggctgtccc ggcggatcgc cgcggagggg ctgatgcggc ggcggccggg
     5281 gtactacgcg gtgcggctgt ccctggtggc cacggcgttc ctgggcgcct gggtggcttt
     5341 cgctctggtg ggggacagct ggtggcagct cgccgtggcg gcgttcatgg cactggcctt
     5401 cgggcaggcc gcgctggtga tgcacgatct ggcgcaccgg cagatcttct cccggcggcg
     5461 gccgagcgag atttggggcc ggctgttcgg gaatctcggg gtgggcatgt cctacggctg
     5521 gtggatgaac aagcacaccc ggcaccacgc caatcccaat cacgaggaac tggacccgga
     5581 cgtcgcgccc gacatcctgg tgtggtcgca ggaacaggcg cgggcggcac ggggaatacc
     5641 gcgtttcatc ggccgtgtgc agggctggat cttctttccg ctgctgactc tcgagggttt
     5701 caacctgcac gtcgcgagct ttcgggcatt gcgctcaacg ccgatgaaac ggcgtggact
     5761 ggaaggcgtg ctgctgaccg cgcacgtgct gatctatctg ggcgtgctgt tcaccgttct
     5821 gtcccctggc aaagccgtgg ccttcgtgct ggtgcaccag gctctcttcg gcgtgtatct
     5881 gggctgctgc ttcgcgccga accacaaggg catgccgacg ctcaagggtg acgatcgccc
     5941 ggactttctg cgccgccagg tgctcacctc gcggaacgtc acgggcagcg tgttcaagga
     6001 catcgcgctg ggcggactca actaccagat cgagcaccac ctcttcccgt cgatgccgac
     6061 cccgcacctg cgcagggccg cgccgatcgt gaagcagtac tgcgcggagg tgggcgtgcc
     6121 ctatcacgag acggggctgt tcgcctcctg gggcgaggcg gtccggcatc tgcacaccgt
     6181 gggcgtaccg atccggcaag agccgcgttc ctgaccgcga ccgggggcgg ccatcgtgcg
     6241 cgggccgcgg tgcgcagggc aggctcccag ggagggcctg atggcgccta tccgatcccg
     6301 tcatcctctc cgatcctgtg ccgggcagta cggcaagcgc gttgttgcct gcggcaaggg
     6361 cctcgtccag ttcggcggct gcggccagga tgcctcccag gtgcacgtaa caccccggtc
     6421 atgctgtgcg cgagagggag cgcgagagcc gcacttttcg gcgggctgcc cggacatgtg
     6481 gccggccgtt cgcggatctc gtgcgagagc cccggccgcc gcagtgacgg ccgggacgcg
     6541 gtgctgttcg ttcagtcgga cgtcgggggg cggcggtccg gcggtagctc gtacatgaac
     6601 gcgcgcatcg ggcgtggtcc gctgcgctgt ttcgagcggc ggcgctccgc atagacccgc
     6661 tcgaccatgt cggcgtagcg cggatcggcc cactcacgcc ggtcgccgtg gtcctgctgc
     6721 gcgttcatcg ctgcccgctt tccgcgtccg taccggtcag accgtaccgg ccggggccgg
     6781 tgcggggtcc gccttccgcg gattgccgcc aggcccgatc gggatgcccg ccggtccggg
     6841 ggagtgctgc gcctggggct ccgacctgga tcgggtcgtc gtcgggaccg cgccacagat
     6901 cctggtcgac tggcgttggt ggtgcgggtg agccagtccg gggagtgggt ctcccgcgtg
     6961 ctttcggggc gctgaggaac gtggtgcgcg aactgaccca ggcggtcgag gaccaaggcg
     7021 ggccggctct cgtcgacggc cagggatggt gcgaggggca gttcggtctg cgcggccgtg
     7081 gcgacgaacg caagggcctg gtcgacgata cgttcggcga tgtccgtccg ctcgcgcctg
     7141 cgtcccggcc ggtggctgcc gccaccgtcg cccgtggcga ccacgtcgtg atcgggggcg
     7201 agacgttcgc cgtcgtcgac atgacgggtg gtgttcgcga ctggtgcatc actggtcatg
     7261 atgcgtacca ccaccctgtg ggccgggctc ccactcgggt gcgatagctt gcgggtatgc
     7321 gttcctgact atgcccaccc ccatgtgcgc ggcgtgttgc cccgtggggg aagtgccagc
     7381 agatcagatc tttcctgccc ttatctcttc cgccgggccc ccgctcgtgg cgggaccaat
     7441 ggcagaacac cccctcacgg agacgaacgt gatcgatacc cggctcgaag gcaagaacgt
     7501 cttggtcacc ggtggcgcag ggaacatcgg tgcggcaatc agccgtgctt tcgcggtgca
     7561 gggggcgcgg gtggcgattc actatctcgc gcaggacctt ccggccccgg agggtgcgga
     7621 ttggggccac atcacgcccg tcccgggtga agccgggaag ctggcacagg aactcggcaa
     7681 cggctcggtg gccatcagcg cggatctgtc ccggcctgac ggggcgcgcc agttggcggt
     7741 ggcggccgcg gaacgcctcg gctcgatcga cgtgctggtc aacaacgcgg cccactgcga
     7801 gacgccggac accgtcgacg ccctgacccc tgattcgctg gaacggcact accgggtgaa
     7861 caccatcgcg ccggcgctcc tcatcgccga ggcggcacgg ctgcgcagcg gcgatcagcc
     7921 gctgtccatc gtcaacatct cgaccgacgc cgccagagcg ttccccgggc agatcggcta
     7981 cggaacgtcc aaggcggccc tggaggcact cacccgggcc accgcgctgg acctggccgg
     8041 tcggggtgtc cgcgtgaatg ccgtcgcacc gggtccggtg cagaccgggt ggatcggaga
     8101 ggatctcatc gcccaggcga cagcgatcgt gcccatgggg cgggtgggcg aaccggagga
     8161 catcgcggac gccgtggtct tcctggcctc ccaccaggcc cgctggatca ccggacaagt
     8221 cctccaggtg gccggcggac acgctctctg actgcgccgg tccgttcccc gcggcggcgt
     8281 cctccccgac cagcggctgt cacatctgat cgggctgcgg cgtcagaggt gcgtacccac
     8341 cgacaacgcg gaggagctgg ccatggaagc tcgtttgaac ctcatgcaga tcccgggcgc
     8401 ggccaagttc gggaagcaac tcgcagccgc cgaccatacg ttcccccgct cgacggtgcc
     8461 gggcacgacg ctggagctgg tgaagatccg cgccagccag atcaacggct gcgggttctg
     8521 cacggacatg cacaccaagg aggccgcgca ggcgggggag acctcggtac gtctgaacct
     8581 catcgcgacc tggcgggagg ccaaggtctt caccggcgcc gagcgtgcgg ccctggagct
     8641 gacggagcag ggcacccgta tcgcggacgc cgccggcggg gtcgcggacg aggtctgggc
     8701 gaacgccgcc acgtactacg acgaggacca gctcgccgcc ctggtgtgcg cgatcgccct
     8761 catcaatgcc ttcaaccgcc tgaacgtcct cgtccagcag cccgccgggg actaccagcc
     8821 cggccagttc gggtaacggg ggccaccctc ggccgggcgt ggtcgcggta ttgccgcacc
     8881 aggccgtcgg tgaccgtgcc cacgacgcgc cggaatgcca tggggtccgg ctttccggtg
     8941 ccgtcccggc gcgggccgag cgcggcccgg gggcggccaa ggggcgcgcg ggctaggctg
     9001 ggggcggtcg gccatgcgtt gcgatcgacg gacgggtgta atccgcatta ttcttcggcc
     9061 cgttgatcca cagttcaacc agccaagagg ggcgtgcccg tgaacggcga ctcgccggtc
     9121 gttccccgga ccgaccgacc gcattcggcc cggatgtacg actacctgct gggcggcagg
     9181 gaccactacg cggcggacag cgaggccgcg gacaaggcgc tggcgtcggc ccccacgctg
     9241 cgcatcgccg cccaggagaa ccgcaagttc atcgcccgcg tcgtgcgcca cctcgtgcag
     9301 gaggtcggga ttcgccagtt cctcgatctc gggcccgggc tgcccacgtc ccagaacgtg
     9361 caccaggtcg cgcaggaggt cgagcccgag acccgcgtcg tgtacgtgga caacgatccg
     9421 atcgtgctcg cgttcggcgg ggccatgctg gagcagaacg agcgcaccac cgtcgtgcgc
     9481 ggcgacatcc gtgacccgct cgccgtgctg caccacccgc gcacccgcga gcagttggat
     9541 ctgtcccggc cggtgggcgt gctcgcggtg gcggtgctcc acttcatagg ggacgacgag
     9601 gacccggcgg gcatcgtgcg cgcactcacc ggaagcctgg cgcccggcag ccacttcgtg
     9661 ctgtcgcacg gcaccgccga cctctccgcc gaggcggcga tgggggtaca ggccgcctac
     9721 cgttcgcacg gggtgccgct gacgctgcgc agcaaggagc ggttcacgga gctcttcgcg
     9781 ggtctcgacc tgatcgatcc cgggatacag gtcgtctccg aatggcgcgc caccgagccg
     9841 ccggaggagc ggccctcgca cgccgacgtc tcctggtacg gcggtgtcgc cagactgtga
     9901 ggggaatgtg tgtgttctgc acgcccccga cgtgacaccg gtgactgtct gaccagcctc
     9961 ccgccgtgga aacctcattg tcacttcccg agggagggca atggacaagc ggtacgaggt
    10021 tttctgtctg gtcgacaggc atttctacga ggcccccgaa cgcgccaccg cgcaactcgg
    10081 cggcgagggc caccaggaag ggctgtacga aacggcgcgg cgcgccgtgc cgcagggctg
    10141 gttctccgaa cgcttcggtg attggctgca cttgcagccg cgtgatgcgg tcatgccgcc
    10201 gcagggctgg aaagttcacg tatccgcctg cctcgacaac gccgacaaga ccgccgcgaa
    10261 agtctgggac tattgcgttc cccgccgcat tcccttcaaa ttcgtaccgg ccgcgcatct
    10321 gctctacctc cgcaactcca aatacgccgg gcgtcattcg agcggcaagt tcgtcacgat
    10381 ctacccggcc gacgaggcgc ggctgcgcga cgtgctcacg gagctcggcg acctgctcgc
    10441 gggggagccg gggccctacg tcctgaccga tctgcgctgg gggcgcggcc cgctgtacgt
    10501 ccgctacggc ggcttcgtcc cgcgcttctg cgacgacgga acgggcgcgg tggtgcccgc
    10561 gatcgagaac gcggagggcc gactggtgcc cgaccgccgc gggccggcgt tcaccgttcc
    10621 cgactgggtc actctgccgc cgttcctcgc cccgcacctg gcggcgcgca acggggtcac
    10681 gctcgcggac ctgccgtacc gcatcgagag cgcgctgcac ttctccaacg gcggcggcgt
    10741 ctaccgcggc accgacccgc gcaccggcga ggcggtggtg ctgaaggagg cgcgcccgca
    10801 cgccggtctc gccgcggacg gcgcggacgc cgtcacccgg ctccagcgcg agaaggacgc
    10861 cctcgacctg ctggccgggc tctccgtggc cccggccgtg cgggactggc tcaccgtcgg
    10921 cgaccaccgt ttcctggtga tggaccacgt gccgggccgc acgctcaact cgttcttcgc
    10981 cgaacgccac ccgctgctgg ccacggaccc ggaaccggcc gccgtcgccg actacacccg
    11041 gtgggcgctg acggtgcacg gcaacgtgga acgggccgtc gccgccctcc acggccgcgg
    11101 cctcgtcttc aacgacctgc acatgtacaa catcatggtc ggccccgacg gaacgtccgt
    11161 gaccctgctc gatttcgagg cggcggcccc ggccggtgac ggcgtgcggc agatcgtcgc
    11221 gcaccccggc ttcgtggccc cggccggccg cacgggcttc gccatcgacc gttacgcgct
    11281 ggcctgcctg cggctcgcgc tgttcctgcc gatgaccacg ctgctcgcgg tcgacccggc
    11341 caaagccgcg catctcgcgc gggtggccgc ccgggagttc cccgacgtgc ccggcgcgtt
    11401 cttcgacgag gccgtcgccg agatcgaggg ccgccccggg accgaggtgg ggacgccgcc
    11461 gcgcgccgcg ccgccgtcgc cgggcgactg gcccgccgcc cgcgactcca tggcccgcgc
    11521 gatcctggcc tcggccaccc cggaacgcga cgaccggctg ttccccggcg acatcgccca
    11581 gttcgcgccc ggcggcggcc tggggctcgc gcacggcgcc gcgggcgtgc tgtacgcgct
    11641 ggccgagacc ggcgtggagc ggtacgcgga aggcgaacgc tggctgctgc gccatgccgc
    11701 ggacccgccg cgcaacagtc cgctcggcct gtacgacggc ctcttcggcg tcgtacacgc
    11761 cctgcaccgc ctcggccaca ccccggccgc gctcgatctc gcgtcccggg cgctgggcga
    11821 gggctgggag cggctgcccg tccacctgtt cggcggtctc gccggtatcg gcctcgtgct
    11881 ggacgaactg gccgccgaca ccggcaatcc ggcgctcgcc gtgcacgccg ggcgtgcggc
    11941 aggtcttgcc gcggaacggc tcgcggcccc gcccgagccg cgcggccacc ggcgggccgg
    12001 gctgctgtac ggcgcgtccg gggcggcgct gctgttcctg cgccggtacg aacggaccgg
    12061 cgacgaacgg ctgctcgccc aggccgccga cgcgctgcgc cgcgacctgg cgcactgccg
    12121 gaccgaccgt tccggctcgc tgctcgtcga cgagggcgac cggctcatgc cgtacctcgg
    12181 cgagggcagc gtcggcatcg cggccgtcct ggacgactac cgcgccgcgg ccttcgcggc
    12241 cggccggccc gccgaggagg acctgataca ggtcggccgg caggtgctgc ccgcggcgcg
    12301 gctgcggtac tacgcgcagc cggggctgtt ccgcggccgg gccgggatga tctggcacct
    12361 ctcacgcacc ggggccgcgg gggccgccgc gcagatcgag gcgctggact ggtacgccat
    12421 ggcctaccgc ggcgaactgg ctttccccgg cgagcagatg atgcgcctgt ccatggacct
    12481 ggcgaccggc accgccggct gcctgctggc gctcggcgcc gccctgcacc ccgccgggga
    12541 cgccggggac gtcccgcggc tgcccttcct gccgcgtccg cggcacccac agacccggcc
    12601 cccgtccgcc tgacgggacg ccgtgggcac gaccgcacca ccaacgcacc accacgcacc
    12661 accaacccga gtattcgccc gaggagagga actgccatgt cgcttcttga cctgcagagc
    12721 atggagcccg agacggccac cgatggcggt ggcggtggcg gcggtggcga catcagcagc
    12781 gtcagcctgc tgatctgcga cacccacagc tccaacagcg tcattctctg tctctgattc
    12841 cgttccgggg cagcccggcg gattccgcgg ccccgcgcac accgcgcggg gccgcgcccg
    12901 ttcccggccc aaccgttccg aaggagccgc gaccgcccat gccccagacc cccgcggaac
    12961 cgacccccgc ggaaccggcc ccggccggcc cgactctgcg cgccaccgcc aggcacggcg
    13021 ccgcgcgcat ggccgtgctg tgcctgctcg ccctggccgg cgcgggcgcc gcgctcgcgc
    13081 tgcccgccgc gctcggccgc gccctcgacc tgctgctgac ctcgggtgac gcggtcaccg
    13141 gctggagcct gctgagcgcc gccctgatct gcggccaggc cgcgctcggc gctgtcacca
    13201 ccgtcctgac ggcgagcgcc gacgcccgcg ccgccgcctg gctgcgcggc cggctcctgc
    13261 ggcggctgct cgccgccggg cccggcgccg ccgaccgctt cccgcacggc gacctcgtca
    13321 cacgcgcagg cggcaacgcc gtccacgcgg gcgccgcgcc cgccgcgctg gccgcggcgg
    13381 tggccgccgc ggtgaccccg gccggagccg tcgtcgccct cgcgctcacc gacccgcggc
    13441 tcgccctggt cttcctcgcc gggctgccgc tgctcgcgct gctgctgcgg gcgttcgccc
    13501 ggtccgcggg cgacgcgttc gcggactacc agcactgcca ggccgatatc gccggccgcc
    13561 tggtggacgc gctgcgcggc gccagaacga tcgccgccgc gggcaccgaa cgcgcggaac
    13621 gccgccgcat cctcgccccg ctgcccggcc tcggcgccca cggacaccgc atgtggcggg
    13681 tcaccgcccg cgccaccgcc cgcgccgccc tgctcacccc gctcctgacg ctgtccgtcg
    13741 tcgcgaccgg cgggctgctg ctcgccgccg gggacctcag cgtcggcggg ctcctcgcgg
    13801 tcgccaggta cgcggcgctg gccgccggca tcggcctgtt cgtcggccac ctcaaccgcc
    13861 tcgtgcgcgc ccgcgccgcg gcccggcgcg tcggcgaggt gctggccgtt cccccgccgc
    13921 ggtacggcgc gcggacgctg cccgcggacg gccccgggcg gctggagtgc cgcggggtga
    13981 cggcccgccg cggcgggcgc gaggtgctgc gcggcctgga cctcgtggtg ccgggcggca
    14041 ccaccgtggc gctcgtcggc cgttccggcg cgggcaagtc gctgctcgcc gcgctcgccg
    14101 gccgcctggc cgagccggac ggcggcggca tcctgctgga cggcgtgccc ctcgccgacc
    14161 tcgaccggga cgccctgcgc ggcgccgtgg gctacgcgtt cgaacggccc gcgctggtcg
    14221 gcggcaccct cgccggcacc atcggcctcg gccccgggcc cgccccgccg ccccgcgcgc
    14281 acgtcgaggc cgcggccgtg gccgcgcgcg ccgacgggtt cgtccggatg ctgcccgagg
    14341 gctacgcgac ccgctgcgcc gacgtgccgc tgtccggcgg ggagctgcaa cggctcggcc
    14401 tggcccgcgc gttcgcgcac ggcgggcggc tgctgatcct ggacgacgcg acgtcgagcc
    14461 tggacacggt caccgaactg cacgtcgcgc gcgccctggc cgcgcactcc gcggcccgca
    14521 cccgcctgat cgtcgcccac cgcgccggtt ccgcggcgcg cgccgacctg gtggcctggc
    14581 tggacgacgg ccgcatccgc gccctcgggc cccaccgcga actgtggcgg cgcgccgact
    14641 accgggcgct gtgggcgggg gagcaggtgg ccgcggatgc gtgaccacgg ggccttcgcg
    14701 ttcctgcggc gccgccgccg cgccctggcc gccctcgcgg cctggtcgct gctgcccgcc
    14761 gcgcagacgt tcctcctcgg ctacgggctc gcgcgcgccc tggacgacgg gttcctggcc
    14821 gggcgcaccg gggtgggcct cggctggctg gccgcggccg ccgccggtgc ggcggcgggc
    14881 gcgttcggca ccggccgcgt gcaccgggcg gtgggcgcgc tcgccgagcc gctgcgcgac
    14941 cagctggtgc gcgaggtcgt cgcccggggg ctgcaccgcg cggtgcgggc cggccgcccg
    15001 gacggcggca ccgccgacgt ctcccgcctg acccaccagg tggagatcgc ccgcgacagc
    15061 ttcgcggggc tgatcctggt gctccagatg ttcctgtgca cggccgcggg cgccctggca
    15121 ggcctggcct ggctcgcgcc ggtgctgctg ccgttcgtgc tggggccgct ggcgctggcc
    15181 ctggccgtct tctgctggtc gctgcgtccc ctggccaggc ggcagcgcgc cgtgctggtc
    15241 gcggacgagg cgctggccga cgcgttcggt gcgaccgtcg cggggctgcg ggacgtcacg
    15301 gccgcgggcg cggaggaacg gaccgccgcg ggcgtcgcgg cgcgcgtcga cgcggagctg
    15361 gccgccgccc tcgccctggg ccgctggggc gcggtgcggg tggtggccgt ggcgatcggc
    15421 ggtcatctcc cggtgctgct gctgctgttc ctcggcccgt ggctgctgcg caacggcgtc
    15481 acgcccggcg ggctgctcgg cgccctcacg ttcgtcaccc aggcgctgct gcccgcgctc
    15541 caggcgctga tcggaggcat cggcagcgcc ggaacccggc tcgccgtggt gctcacccgc
    15601 ctgcgcggcg accccctgcc gccggacggc ccgccgccgg acggcccgcc gcgcgccgcc
    15661 ccgccgcagg acggcccgtc gctcgccgcc ggtcggcggg cgcgggcgcc gcgcgggaac
    15721 gcggtggagc tgcgcggcgt caccttcgcc tacggcggcc gggccacgcc ggtcctcgac
    15781 ggcgtcgacc tggccgtgcc cgcggggcag cacctggccg tcgtcgggcc gagcggcgcg
    15841 ggcaagtcga cgctcgcggc gctggccgcc gggctgctcg cgccgcgggc cggccaggtg
    15901 cggctgtgcg gcgagccggt cgccgggcgc ggggccgccg acctggccgc gctgcgggtg
    15961 ctgatcccgc aggaggcgta cgtcttcggc ggcagcgtcg ccgacaacct cggctgcctg
    16021 caccccgggc cgccgggcga cgcggcgctg ctcgccgcgg tcggggccgt cggcgcggag
    16081 gaactcgtgg accgcctcgg cggcccaggc ggaacggtcg atccggcggc actgtccgcg
    16141 ggcgaacgcc aactgatcgc gctggcccgg gcgttcctct cgaccgcccc ggtcgtcctg
    16201 ctcgacgagg cgacctgcca cctggacccg gccgcggagg cgcgcgccga acgcgccttc
    16261 gcggcccgcc caggcggcac gctcgtcgtc atcgcccacc gcatcagctc ggcccgcagg
    16321 gcggaacggg cgctcgtgct cgacggcgcg gacctgctca ccggcacccc gcgcgacctg
    16381 ctcacccgct ccgccctgtt ccgcgacctg gccgcgggct ggtcagaccc agccggcgcc
    16441 cctggcgatg cggatggcgt cgacccggtt cctggcgccg gtcttgcgta tcaccgcggc
    16501 gaggtagttg cgcaccgttc cctccgcaag ccataactcc ccggcgatct ccggcaccgg
    16561 ggcgccgtcc gcggccaggg acagaacgcg cagctcgcgc ggggtcagcg gcatgcggga
    16621 ggcgctgagg aagtcgtagg ccagggcgtc gtccacgtaa cggccgccct tggcgaccgt
    16681 gcggatggcg tcgagcaggc gctgcggtgc ggcctccttg ctgacgtagc cgagcgcgcg
    16741 cgcctcgaag gcccggtgca gcaggccggg tctgccggcc ggggccagta ccaccaggcc
    16801 gtggtcctcc gggtcgtaga gccggtgcgg cgccgcggcg tccgccagcc gggcgaaccc
    16861 ggcgcaggtc gcgtcgacga gccagacggc ctcctggcgg tgcggctcca tccgtgccca
    16921 ttcttcccag gacgcgggaa tgacgtcgat gtcctcctcc gcaccgagca gtgaggtcag
    16981 cgcgcagcgc agcaaggtgt catcgtgcac gaacagcaac cggatcacgt gtggtgcctc
    17041 cttgggcggt gactcggact cgtccctcga ccacctagtt tcctcatatc cgtgccctgc
    17101 ggtccgggga acgccgaccc ggcccggtat gggcaggaag cacgccgggg cgcacggggg
    17161 cgcacggaag aaatgcggcc cgcgtattcc ggacagtttt ccggggcacc ggcgggaaaa
    17221 cgcgtccaac ggggggcatt ttccccgggc aatttcctgc ccgataccac ggaattgcgt
    17281 tcggcggggc ccgaatgcgg aatcacgcgt aatgcggaaa cggggggagc gggccgtccg
    17341 gacggcgccg gggcagggcc ggcgggcaga gccgacgagg ctcaggcggc gggactcggc
    17401 cgccgggact caggcggcgg ggctcaggcg gtgggtgccg ccgtggaggt ggccgcggcg
    17461 cccttggcgg gcgcgcggcg cagcaggcgg acggcgacgg cgcccgccgc gatcagggcc
    17521 accatcgaca ggccggtgct gaaccagctg gcgcccagca gctgaccgcc gaggtagccg
    17581 atgccgacgc tgtacccggt ccacaccacg gccgcgagcg ccgaccaggg caggaagtcc
    17641 cgcgtgcgcc gctgggccac gcccgcgccg aggctgacca cggcgcgtcc ggccggggcg
    17701 aacctggcca gcacgaccag cggcccgccg ccgcggacca gggcggactc cagccgcttg
    17761 tgggcggcgg acagccgccg cgagcgcgcg atggcgctgt cgaagcggcg cccgccgcgg
    17821 agcgcgagcc ggtaggcgag caggtcgccg acgatcgagg cgctggtggc gcacaggacg
    17881 agcacgagca ggtgcggcag ccgggggtcg gcggagccgg gcccgggcag gcccgcgaca
    17941 tcggcggcgg cgccggcggc cacggtggcc gcggtcacga ccagcgcgcc gctgggcagg
    18001 agcggcacga agacgtcgag caggatggag gcggcgacga tcacgtagat ccacggggcg
    18061 tacagcagta tccccaaggt ctcctgcacg gtgtccccga ttcccctgtc cggtgccgtg
    18121 tgcggctgcg tgttcgatct gacgcgctct tgcacggctt tggttccgcc gtacagcgta
    18181 cgcctgggtc ctccgcgcgg tgcacgcggg tgcgtgtggt gggcatctca aagtctgcac
    18241 tgtgcagggt gaaccggggg aaggcaatca ccatgaagga gatcggatga aaattctcgc
    18301 gacgggcgcg gccgccatgg cggcggtgct cgccacggcg ggcgccgcgg tggccgctgc
    18361 cggacagggc gatgtgctgc tgtacgacgc cgggcgcttc gccccggtgg gcgaggcggg
    18421 cggcgaggtg ccgaaggcgg tgacctacga cgaggagctg gtgccggccg gttccacgat
    18481 ccacgtcgcc caggccatca ggggtgaggc catgcagatc gaggttgccg cgctcggcct
    18541 ggtgcccggc cacacctacg gcacccacgt gcacaccgaa ccgtgcggtg ccgacccggc
    18601 cgacgcgggc ggccactacc aggaccagcc gggcgtggtc gacgcgcgga acgaggtctg
    18661 gctggacttc acggtcgacg cgcagggcgt gggcaaggcg gaggtcggca agaactggct
    18721 gttccgcacg ggcggcgcgg gctcggtggt gctgcacgag cgcgccacgt ccgagggcca
    18781 cgacgagcac ccgccgggcg acgcgggcgg ccgggtggcg tgcttcaccc tcccgttcgc
    18841 cggcgaggac gcggccgccc gctgagacgg cggcggcgcc acggcccctt cccgcccggc
    18901 ccacccgggc gggaacccgc ccggcgcgca acgccgttca cacctgtgcg ccccccggtg
    18961 aacggtcgcc ggtgaacggc cgtcggcggg cggtcagggg caggcggtca gcggcggacg
    19021 atcacgggct gacggtgagg cggatgaggc cgtcggccgg ggggaagccc tcggggcgtg
    19081 cccggggggc cgcctcgacc cgcacctgct ccagggtggc ggcgtaggcg gtgggggcga
    19141 gcgccgcggc ccgcgggccg acgccgatca cgcgcatccc cgcggcgcgg gccgcggcga
    19201 tgcccgcggc ggagtcctcg aagacgaggc agtcggccgg gtccacgccg agctcggcgg
    19261 cgcccttgag gaagccctcc gggtccggct tgctcgcgct gaccgactcg gcggtgatcc
    19321 gcacgtccgg catccgcagc ccggccgccg ccatgcgcgc gtcggacagg gcggtgtccg
    19381 cggaggtgac cagcgcgtgc ggggccgcgg cgatggccgc gaggaagtcc tgggcgccgg
    19441 ggatgggcac gacgccctcg gtgtcggcgg tctcccgggc cagcagccgg gcggcgtccg
    19501 cccggtgctc cgccatcggc cgctcgggca gcagctcggc catggtggcg tacgcctgcc
    19561 gtccgtgcat gatcgcgaag acgcgggccg ggtcgacgtc ccgcgcctcg gcccacgacc
    19621 gccagacgcg ttcgacgacc gcgtcggagt cgagcagggt gccgtccatg tcgaggagga
    19681 gtgcgcgggc cgtcagggtg aggggcgaca tcggtggcag gctcctgggg cgatgcgggc
    19741 ggacgggaag ccagtggccc cgcccgttta cggtcgggga agcgggcgga accactttgt
    19801 ttttcaacgg tacaaaaccg ggggcgggtt gcgccacccc ccaccggcat ccggaacgaa
    19861 agcgtcgccg cgcgttcgac cccggttcac gtcgggccgc cccgcggcca ctcggcccgt
    19921 gagccgccca gctcccggct gaggtcgtgc accagctcgg ccagatcccg cggccggtcc
    19981 gggccccacc agtcgccgag cagctcgccc agcgcgttct cccgcgcctc ggccagccgg
    20041 tccgccacgc ggcggcccgc gtccgtgagt accagcgaca ggccctgccg cacggcgagc
    20101 ccgcgttcct ccacctgccg cgcggccgcc gtcacgacgt cgagcggcac cgcggcccgg
    20161 tccgcgagca gccccggctc cgccgagccg tcccgcgcca tgcgcagcag cagccagcac
    20221 gcggccggca gcaggtccac gccggccgcc gcggcgatcc gccggtacat gtcgcgccgc
    20281 ccggcgcgcg agccgagcgc ggacagcgcg cgggcgcact cctcgcggga cgaacgctga
    20341 acggggctcg gcggcaccgc ctcgccgagg tcgggggcgt ggacgctttc gcgcaacggg
    20401 tcctcgcgca gcagccaggc cagcacgtgg gcgagcacga ccaccgggac cgcgtacagg
    20461 aacacggcgg tgatggcgtc cgcataggcg ccgagcgccg ccgcgcgggc ggcggcgggc
    20521 agggcgccca ggccctccgg gtcgtgcagc agcgactcga ccgtcacgcc cgcgggcagt
    20581 tccgcgccgc ccagcgcgtc gtgcagaccg tcccgcaggc ggccggtgaa caccgtgccg
    20641 agcaccgcca cgccgaaggc cgcgccgatg gagcggaaga acgtcacccc cgacgtcgcc
    20701 acgcccaggt cgccgtaggg caccgcgttc tgcacggcca gcaccagcac ctggagcacc
    20761 atgccgatgc ccatgccgaa cacggcgaag cagacgccca tctccaggtt gccgctgtcg
    20821 cggtcgaggg tgtgcaggag caccaggccg acggcggtga cggccgtgcc gagcacgggg
    20881 aagaccttcc accggccggt gcggctgatc agctgcccgg agagggtcga ggtcagcagc
    20941 agcccgagca ccatcggcag caggtgcacg ccggagaggg tgggcgagat gccgtgcacc
    21001 acctggagga aggtgggcag gtaggtcatg ccgccgaaca gcgcgaagcc gacgacgaag
    21061 gcgatggcgc aggacagcgt gaacgtccgg ttgcggaaga gggccggcgg cagcaccggt
    21121 tctgcggcgc ggcgttccac ccgcacgaac gcggccaggc acaccgccgc cggcacggcc
    21181 agggcggcga tctgccacga gccccagtcc caggtggtgc cgccgagcga ggcgatgacg
    21241 acgaaggccc cggcggccgc ggcgatgagg agcgagcccg cgtagtcgat cacgtgccgc
    21301 tcccggcggg ccgggaggtg caggacggcc gcgatcaccg ccagcgccac gccgcccacg
    21361 ggcacgttga cgtagaacac ccagcgccag ccgaggtggt ccacgaacag cccgccgagc
    21421 agcggcccca gcacgctggt ggcgccgaag acggcgccga acaggccctg gtaccggccg
    21481 cgttcgcgag gcggcaccag gtcgccgacg atggccatgg agagcacgat cagcccgccg
    21541 ccgccgagcc cctggaggaa cctgaaggcg atcagctcgg gcatgttccg cgcgagaccg
    21601 cacagcacgg acccggccag gaagatcacc acggccgtct ggaacagcct cttccggccg
    21661 tattggtcgc cgagcttccc ccagagcggt gtgcctgccg tggcggccag cagataggcg
    21721 gtgacgaccc acgagaggtg gtcgaggccg ccgagatcac ccacgatcgt cggcagcgcg
    21781 gtggcgacga tcgtctggtc gagcgcggcc aggaaaaggc cgagcagcag ggcactcatc
    21841 gacagccaca gggtgccgcg ggactgccgg gcgggcgggg gccgcacggt catgggcgcc
    21901 tcctcgcgct cgtcgcgggc gccggcccgg tgccggcgcc gcaccgctgt cacgcgggtg
    21961 tccggcgcac acgtggtctg cacgtgcagc gttgaggcca ttttgtccgg aatctgcgtg
    22021 tccggcttgt tgagcgactc cccggccacc cccacccggg tggtgcataa tcgctgccaa
    22081 tcgaccggga ggggagcgcg cgatgaccga ccgggccgag tgtctgatat gcggtcggcc
    22141 ctcgctgtcc accggagagc cggactgccg gtgctggacg cactccctct cccacccggt
    22201 cgaccccccg cagcacggcc ccgatccggc cgacgtcgcg ctgttccccc tcgacccgtc
    22261 cggcccgccc ggcccgccgg cccccgccgc cgcgccgccg ccgcgggacg cggattccgt
    22321 ggtcgtgcac ggctcgcacc gcccgcccgc ctcccaccgc aagccgcggg aacgccaccg
    22381 catcgccgtg gcggccggcg gggccgtcgc cgcggtcgtc ggctgcaccg cgctcgccgc
    22441 ctcgctgctc ggcggcaacg ggcgccacga acaggtcctc gacaccgacg gcaccgggcc
    22501 gagcgtcgcc ctgccggacg gccaggaggt cctgcccgac cgcggggagc cgccgcccga
    22561 gccggaaggg gacaccccgc ggccggggcc caccccggag accgaaggga ccg
//
