LOCUS       NZ_LZNS01000001        24370 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5531094
            Orig. end                         :: 5555464
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24370
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="28"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24370
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24370
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14370](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14370)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            1177..2370
                     /locus_tag="STBA_RS24985"
                     /old_locus_tag="STBA_50640"
     CDS             1177..2370
                     /EC_number="2.4.1.129"
                     /GO_function="GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432864.1"
                     /locus_tag="STBA_RS24985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50640"
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_077061386.1"
                     /transl_table=11
                     /translation="MSVHTLTLGGSAARKSTWRRLAARDSVARRVDWILLLAALALSVL
                     GAVLVWSATRNRTEINGGDPQFFLVRQGINLAVGVALAIGVMWLGHQRLRSAVPLFYTF
                     SLGAMLLVFSPLGTEINGQRAWLSLGGYTLQPGEFAKVAVVLGMALILAAQVDAGDRDY
                     PGSRAVFQALALAGAPLAIVVIDDMGMAMVLGMIVLGVLLASGAPLRWSIGLVLAGIAA
                     AVLVWALGVLDQYQLDRFAAFADPSRDPAGVGYNTNQARIAIGSGGLDGKGLFQGTQTT
                     GQFVPEQHTDFIFTVAAEELGFIGAGGIIVLIGIVLWRALRIARGATDLYSTIIAAGIV
                     AWLAFQCFENIGMALGIMPVAGLPLPFLSYGGTSMFAVWVAIGLLQSVRMKRPLSAA"
     gene            2443..3927
                     /locus_tag="STBA_RS24990"
                     /old_locus_tag="STBA_50650"
     CDS             2443..3927
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950912.1"
                     /locus_tag="STBA_RS24990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50650"
                     /product="CYTH and CHAD domain-containing protein"
                     /protein_id="WP_077061387.1"
                     /transl_table=11
                     /translation="MTTKQEISSTKETERKYEGPVPLPELAGTGPVHTTRDPGGLLLDA
                     VYYDTADRRLAAGGVTLRRRTGGADDGWHLKLPLGGSSREEIRAPLTDQLPDSLLALLR
                     ARIRREPIGPIVSLHTDRRRRLLLDVEGTALGEVAVDMVTARRDGRTAEWTEIEVELAD
                     GADPAVLDAVEERLAAAGLRPSGGASKLARALAETAEATAWAAPDAAGGTAGGDVLAYA
                     RRQWEILVGLDPAVRRERPGSVHRMRVATRRLRSCLRSHGKTLDRAATKPLAEELRWLA
                     GELGVDRDREVLAERLGTRLAELPPELVRGPVPLRLARRDGIARQASGAGVTAALDSPR
                     YLSLLDTLDLLLGTSPPLTDAAGRPAAKAMTKTLRREGDRLARRLDAALAAEPGPGRDA
                     ALHRARKAAKRARYAAEAARPALGKKARRTGKRFKRVQQVLGDHHDSVVARAALRQVAA
                     EAEAAGEPSFTYGALHGRETGLAAAGERAAGRLRVR"
     gene            3976..5919
                     /locus_tag="STBA_RS24995"
                     /old_locus_tag="STBA_50660"
     CDS             3976..5919
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432865.1"
                     /locus_tag="STBA_RS24995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50660"
                     /product="TIGR03960 family B12-binding radical SAM protein"
                     /protein_id="WP_077061388.1"
                     /sec_met_domain="PF04055 (E-value: 5.6e-16, bitscore: 58.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVESVFPRLEALLPHVQKPIQYVGGELNSTVKDWDACDVRWSLM
                     YPDAYEVGLPNQGVMILYEVLNEQEGVLAERTYSVWPDLEELMREHGVPQFTVDAHRPV
                     SAFDLLGVSFSTELGYTNLLAALDLAGIPLSARERTTDHPVVVAGGHAAFNPEPIAEFI
                     DCAVVGDGEQAVLDITRIVRAWKAEGRPGGRAELLLRLARSGGVYVPGFYDVEYLPDGR
                     ISRVVPNRPGVPWRVAKHTVMDLDEWPYPKQPLVPLAETVHERMSVEIFRGCTRGCRFC
                     QAGMITRPVRERSITGIGDMVDKGLEATGFEEVGLLSLSSADHSEIADVAKGLADRYEE
                     DKIGLSLPSTRVDAFNIDLANELTRNGRRSGLTFAPEGGSERIRKVINKMVSEEDLIRT
                     VATAYGNGWRQVKLYFMCGLPTETDEDVLQIAEMATRVIAKGREVSGSNDIRCTVSIGG
                     FVPKPHTPFQWAPQLSAPETDARLAKLRDAIRADKRYGRSIGFRYHDGKPGTVEGLLSR
                     GDRRVGAVIRAVYEAGGRFDGWREFFSYDQWMACAEGALTPQGVDVAWYTTRERGYEEV
                     LPWDHLDSGLDKDWLWEDWQDALDETEVEDCRWTPCFDCGVCPQLDTKIQIGPTGKKLL
                     PLQVVKSGAEPR"
     gene            complement(5975..6349)
                     /locus_tag="STBA_RS38395"
                     /old_locus_tag="STBA_50670"
     CDS             complement(5975..6349)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS38395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_50670"
                     /product="hypothetical protein"
                     /protein_id="WP_077061389.1"
                     /transl_table=11
                     /translation="MHDWCDAEAWDRFLYERYGEHRRSMLRTLDTWISAAADQCAGRGI
                     PLVFGEGWIGCTPLSGNFEEGPVGAEVCREAVRLSARAGAWGTIVCSNAAPHHPMWNDI
                     ALQRECNGTFSGTETSPERS"
     gene            complement(6382..6864)
                     /locus_tag="STBA_RS38400"
                     /old_locus_tag="STBA_50680"
     CDS             complement(6382..6864)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS38400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_50680"
                     /product="hypothetical protein"
                     /protein_id="WP_216355965.1"
                     /transl_table=11
                     /translation="MAVEPEDRPTRLADALADAYELAEAEGLAEVIAFVELHNEVQGGY
                     LTEGLPGREPAVVELRERLERGLARFHERQPDVPVTVNYARVPLDAFRGIPENIDVGVF
                     HPYVYGVLDELVVGYGLRSTDGGFDEERARADLMRPGAPAPRRSASGVRPPARNGG"
     misc_feature    6816..6830
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(7298..9673)
                     /locus_tag="STBA_RS25015"
                     /old_locus_tag="STBA_50690"
     CDS             complement(7298..9673)
                     /EC_number="3.2.1.23"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013469.4"
                     /locus_tag="STBA_RS25015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50690"
                     /product="beta-galactosidase"
                     /protein_id="WP_077061392.1"
                     /transl_table=11
                     /translation="MVYKVTLRPSAESFGGHLRMGEPEGQPDRIAATSTHLVRGGRPWF
                     PVMGEMHFSRCPREAWRERLLNMRAGGIGVVATYLFWHHHEEQQGEFRFEGNRDIRAFV
                     EQTGAYGMDAVVRIGPWAHGEARYGGFPDWVQHSGTRTRTDDPAYLDLVRPYYTRIGAE
                     LDGLHHTQGGPIVAVQIENELYDQPEHLRTLKRMAQDAGITPPLWTATAWGEAQLPADE
                     FLPVYAGYPEAPWDDAHPGWARHNRRHFFFTALRDDHTVGADLRRRPTAGQGPDPGRYP
                     YATCELGGGVQATYHRRPLVPPEDVAALALTKIGSGSSWQGYYMYQGGTHVTDAATTMQ
                     ESTDTGYPNDLPVISYDFQAPLGEYGQVRPAYGLLRLQHHLLAAAGERLAPMPFAAPDR
                     SPRDLDDRETLRWAARSDGTSGMLFVNTHQPGGETLAAHRAVRFRLDTADGPLELPTEP
                     ADIPSGAYFAWPFRWPLPGAATLESATAQLVAVLDDMVVLTRTAGIPVELVLTGVDPAS
                     VEGPGVIVDDLGADRTRIRVPHPGTDALIRLDGLRLLVLDEHTARHTTVGELWGTRRLL
                     VGDGIHVVPDGRHLHIESGPAGGTLLVLPAPTGTVAPRDLATSRLRLRATGESGIFARF
                     EVDAPTAVPEAALVELAAAKGPAPQRIGGPLKRAAAPTDADYALAAAHRVEFDHEAFTA
                     AHRLLLRLDWVGDVARAEIGGTPVADQYWNGAPWEIDLTRHRAALEDGAELVLRLLPFD
                     PAAKIHVPDHQRPDEVTLRLREARLVPVYRAAVGIGAP"
     misc_feature    9752..9761
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.18"
                     /tool="antismash"
     misc_feature    complement(9752..9766)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.99"
                     /tool="antismash"
     gene            complement(10001..11293)
                     /locus_tag="STBA_RS25020"
                     /old_locus_tag="STBA_50700"
     CDS             complement(10001..11293)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058432.1"
                     /locus_tag="STBA_RS25020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50700"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_077061393.1"
                     /sec_met_domain="LANC_like (E-value: 6.1e-47, bitscore:
                     158.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAWSDEAVVAEIAARANAWTPPARQPLGLADGTIGTALLLAELS
                     RHDPELRRAAHARLTDAAKTLLPVAGRLGPGLYQGAAGLAFAIRAAVRKPGDYATIRER
                     LDTFLRERLGRLLALEEARMSEGKELVPRERFDAVTGVTGIARYFLDGPAVPSRSTETA
                     GTADPAGPQAVRDALRYLTALTEPRVHEGRTLPGWAGPPWPGQEADGDTIDVGLAHGIA
                     GPLVLLSLCWSRGIRVPGQDAAIRRAAKWLLSWRQDDEAGPYWPMMVSAADEAAGRRPR
                     HEPHRPSWCYGPPGIARALQLAGLALGETEWPRVAVDAMHAVLRRPEGRAGLDDPGLCH
                     GLAGQAHLTRVIAHDAQDPILAEHAASLTDRLRARFEPASAFGYPTRGRRRLPPAIWDA
                     PTFLEGSAGVALVLHRRGPTPPRWDAALLVN"
     gene            complement(11290..14370)
                     /locus_tag="STBA_RS25025"
                     /old_locus_tag="STBA_50710"
     CDS             complement(11290..14370)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058431.1"
                     /locus_tag="STBA_RS25025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50710"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_253194980.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 8.8e-179,
                     bitscore: 594.4, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.2e-16,
                     bitscore: 59.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.3e-30, bitscore:
                     104.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRIPLLPYSWVERTVAAAEGLDPRDRAQVERYVATLIADERVLE
                     ALLLSSPSLHRAIRTLQAGEPMKPAALRKLTLGTTRYVLRAAGRPTPFGLLAGVAPVAF
                     GDACRARVGERHRVAVRPDGDWLVGLLSAWERDPALLRRLRVVTNDLGFARGDRWVLPF
                     TPVTDEGRAAAARTKEVSVRHTAAVRLALEAAEQPCTGGEIAERLTSAFPAVAAGKVDG
                     LLADLVRRGFLLTELRPPLARADPLLYVREVLASVADREKEDAVARIAKVLADCAGAPL
                     GAGTGRWDTAERALRDLHRHDGTLLQTDLRIDAEVILPEAVAREAESAATALWRASAKD
                     ERKPHLADYHRAFVERYGVGHAVPLLEVLDPHSGLGPPAGYENPGGERRVAPAAADRGP
                     ARDAVLTDLVLSAAAGSGEIVLGDAVLNRLADAAPDTAPTPAELCAQVTAVSQEALARG
                     EFRLILSQTTGSPTPGALFGRFAYLFDDQEPVAALARDAMATTLREGATPVSLDFQVLP
                     GAANVTRALACWPDRLTVGSFPHHPSSGGRVRGARDVALAADEERLFAVDAATGRELVA
                     HTATVLSMGFTSDAVRLLREISSMGRPTWSVWDWGAIGSATRLPRVRHGRTVLTPARWK
                     MTDPALTDSSASDEEWGRALDAWRARWAVPRRVNVGTVDLRVVLDLSAPLHRTLLRRQL
                     ARDPGTVAYETLEDAGYAEHWLRDDEGGAYRSEVLIPVLPRGRDGRDSRDAGTARAPAG
                     MARRGPAPRQGNRHRQWYYAKLYLATAGQNEVLASHLPRLLANLPDGGGHWFFIRYIDP
                     EPHLRLRFPGDPRALLSDVAPAVQDWADDLYRRRLAGRLAVDRYEPETVRYGGPGAIAA
                     AERFFHHDSRTVVGQLAALSAGTVTTPPPVLAAGHYVDIARQVHGPDWPAWFLAMPREE
                     EHHRYFREHRDAALGLLGTAPPPGTSASGQADPAGLAERAAALRDFPAASRRSVLAGVL
                     HMHHNRLIGANRTSEERSFAVARGMAQTEQARREHLR"
     aSDomain        complement(13651..13935)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_STBA_RS25025_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="4.80E-19"
                     /identifier="RREFam001.1"
                     /label="STBA_RS25025"
                     /locus_tag="STBA_RS25025"
                     /protein_end="240"
                     /protein_start="145"
                     /score="59.8"
                     /tool="antismash"
                     /translation="VVTNDLGFARGDRWVLPFTPVTDEGRAAAARTKEVSVRHTAAVRL
                     ALEAAEQPCTGGEIAERLTSAFPAVAAGKVDGLLADLVRRGFLLTELRPP"
     misc_feature    complement(14413..14427)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.27"
                     /tool="antismash"
     gene            complement(14561..14755)
                     /locus_tag="STBA_RS25030"
                     /old_locus_tag="STBA_50720"
     CDS             complement(14561..14755)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS25030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_50720"
                     /product="hypothetical protein"
                     /protein_id="WP_077061394.1"
                     /transl_table=11
                     /translation="MSTSVAEPTTELTDSDFDLDIRIELSDLEDGDGFAQAKTVSFPNG
                     PYTSDCSVCIPATTAIFCS"
     CDS_motif       complement(14648..14755)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSTSVAEPTTELTDSDFDLDIRIELSDLEDGDGFAQ"
                     /locus_tag="STBA_RS25030_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14561..14647)
                     /prepeptide="core"
                     /locus_tag="STBA_RS25030_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-0.70"
                     /molecular_weight="2737.1"
                     /monoisotopic_mass="2735.3"
                     /core_sequence="AKTVSFPNGPYTSDCSVCIPATTAIFCS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSTSVAEPTTELTDSDFDLDIRIELSDLEDGDGFAQ"
                     /leader_location="[14647:14755](-)"
                     /alternative_weights="2755.1"
                     /alternative_weights="2773.1"
                     /alternative_weights="2791.2"
                     /alternative_weights="2809.2"
                     /alternative_weights="2827.2"
     misc_feature    14755..14770
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.73"
                     /tool="antismash"
     misc_feature    complement(14819..14829)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    15091..15107
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.25"
                     /tool="antismash"
     gene            15473..15874
                     /locus_tag="STBA_RS25035"
                     /old_locus_tag="STBA_50730"
     CDS             15473..15874
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS25035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_50730"
                     /product="hypothetical protein"
                     /protein_id="WP_077061395.1"
                     /transl_table=11
                     /translation="MSVTASVTLTEWTPAALFRKWITDRCGADVLDFIQQLHAEHEVLA
                     GPTAANTDRHLAALTTVPWLLHAAVAAKIVALDHLTGRAAESPDRGAFWQARPAFVRLL
                     PYFRRVHQVGMSTAHGEPLARCPTSAGEP"
     gene            complement(16030..16380)
                     /locus_tag="STBA_RS25040"
                     /old_locus_tag="STBA_50740"
     CDS             complement(16030..16380)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS25040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_50740"
                     /product="hypothetical protein"
                     /protein_id="WP_077061396.1"
                     /transl_table=11
                     /translation="MYRVTVPASALAGDGEVRLRPRYTGDAARAHIGGRLVADHFWYRP
                     EWEIGLRRFADAAARHGVEIRVLPLDPASRVHVDASAREGLDAARNRAAVETAELAGVP
                     RASLRGAGDERA"
     misc_feature    16689..16702
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.73"
                     /tool="antismash"
     misc_feature    complement(16691..16704)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.86"
                     /tool="antismash"
     misc_feature    16692..16707
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.18"
                     /tool="antismash"
     misc_feature    16732..16746
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.37"
                     /tool="antismash"
     gene            16776..17498
                     /locus_tag="STBA_RS25045"
                     /old_locus_tag="STBA_50750"
     CDS             16776..17498
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040880.1"
                     /locus_tag="STBA_RS25045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50750"
                     /product="FCD domain-containing protein"
                     /protein_id="WP_077061397.1"
                     /transl_table=11
                     /translation="MASYTGRGVHGQVVRVLGLRIVGGDLPEGATLDMRGLGEELDVSL
                     TVMRESMKVLAGKGLIDARQKRGTFVRERSNWNLLDADIIRWQVESGAGQRLMRDLAEV
                     RAIVEPAAAHRAALNRTEGDLRALETALDAMTHARAHFSADAAEADAAFHRALLCATGN
                     EMLARMDLLLEPGLRERDRVVHSHDQANDPVPSHRAVLDAIRDQDPARAELAMLDLLAK
                     ATHDLDRITGSVSAAHQP"
     misc_feature    complement(17926..17940)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            18145..18690
                     /locus_tag="STBA_RS25050"
                     /old_locus_tag="STBA_50760"
     CDS             18145..18690
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432866.1"
                     /locus_tag="STBA_RS25050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50760"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_171987782.1"
                     /transl_table=11
                     /translation="MPQLVQPTTAVHASFLEAVEEFEAEGRGTLEDNSMLGRDISVFGR
                     RWQDPETFAQYVAENIAAARDDTLPPPGFVRATILWWVEGDTFLGRLSIRHRLTRRLLD
                     WGGLIGYDVRPSARRRGHATGMLRASLPLARRLGHDPVLVTCDHDNVASRKVIEACGGV
                     FEDRRGEKLRYWIATGGT"
     gene            18795..19586
                     /locus_tag="STBA_RS25055"
                     /old_locus_tag="STBA_50770"
     CDS             18795..19586
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432867.1"
                     /locus_tag="STBA_RS25055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50770"
                     /product="TIGR03936 family radical SAM-associated protein"
                     /protein_id="WP_077061398.1"
                     /transl_table=11
                     /translation="MQRIRMRYTKRGRLRFTSHRDFQRAFERALRRAGVPMAYSAGFTP
                     HPKVSYANAAPTGTASEAEYLEIALTERRDVEELRARLDASLPDGLDIVDMVEARTTDF
                     AEQLQASQWELRLDGVQPLDADRAVAAFLAAEAVEVQRRTKKGLRAFDARAAVVSLATV
                     PSGTAAGGSHGPDTQPCAILRLVVRHLTPAVRPDDVLSGLRAKADLAPPVPAAVTRLAQ
                     GPLDEENGTVTDPFAPDRDAAEAALTRAAGQQAAAAPGVTG"
     gene            19784..23581
                     /locus_tag="STBA_RS25060"
                     /old_locus_tag="STBA_50780"
     CDS             19784..23581
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136189.1"
                     /locus_tag="STBA_RS25060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50780"
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="WP_079252149.1"
                     /transl_table=11
                     /translation="MHEANESVGPNGAERTGDTPAATTTTDKNTTPSDTLPPRRRRAAT
                     RPAGPPAAVAEEESRTDEAEQAAPRKRRRVTRVASEPETEAQQEPQQEPVAAEAEAEGA
                     APRKRRRATRAVSAPEPVAEEAVAEEPPAEEAAPARKRRRAAADEPVAAEAEAEGAAPR
                     KRRRATRAVSAPEPVAEEAVAEEPSAEEAAPARKRRRAAADEPAAAETAPARRRRRTAS
                     VPEAVEEPAAAEPAAEPEPEPEPAAPRRRRRAARAAGEAAETPAEEPQITAQEPEQAVE
                     APTSRRRRRSAREAAEPEAVAEVPDEADAAAVPDESDTPLPPAVPVATAVFQAPVFQAP
                     MFQTPQRAAEEAVRSAAPATGPEEAEGPEEPEDEDEQDVEDVEDVAEEEDESQADRPAR
                     RRRRGGRRRRRGETAERAAAAVAGTDAGDGDEETAPEAEAEPESGAAEPAKDADVDEDA
                     DAEAEAEEQAEGGGSSRRRRRRRRRSGDSGDGAGGDDPERTVVKVREPRRKRDEATESS
                     DGVQSIKGSTRLEAKKQRRREGREQGRRRAPIITEAEFLARRESVERVMIVRQSGERTQ
                     IAVLEDDVLVEHFVNKEQSASYVGNVYLGKVQNVLPSMEAAFVDIGKGRNAVLYAGEVN
                     FEALGLGNGPRRIESALKSGQPVLVQVTKDPIGHKGARLTSQISLPGRYLVYVPEGSMT
                     GISRKLPDTERTRLKQVLKRIVPENAGVIVRTAAEGASEDELTRDVERLQAQWEEIRKK
                     AKKGNAPALLYGEPDMTVRVVRDIFNEDFSKVIVSGDDAWETIHGYVAHVAPDLQERLQ
                     RWTSDVDVFATYRIDEQLMKALDRKVWLPSGGSLVIDRTEAMVVIDVNTGRFTGQGGNL
                     EETVTRNNLEAAEEIVRQLRLRDLGGIIVIDFIDMVLESNRDLVLRRLLECLGRDRTKH
                     QVAEVTSLGLVQMTRKRVGQGLLESFSEPCVHCNGRGVIVHADHVHAPGGGGGGKKSRK
                     RARAAAAEEPQPTAAEAQPAPAAVAESAEPVEPIVPPETVERNEPVEPVEPVEEPVEPS
                     PEPRRRRRVSRKASAPAGPAGEGAVTVVTAEQPSAAAEPEPAPEPEPEPAPEPEPATAR
                     RRGSRKVSVPAGAPRSAEEPAVVVVTATEPEPEPVREPEAVREPEAGTVSEAPPRRRAV
                     RRASAPAGSPEGATEAVVTVVTAGAAKKSAKKTATKSAAKTAAKKTAKKTAKKTAAKKT
                     ATKKTAAKKTAKKATAKKAAKATSAAEQQQPPSVSATAGE"
     misc_feature    23633..23648
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.09"
                     /tool="antismash"
     gene            23814..24134
                     /gene="rplU"
                     /locus_tag="STBA_RS25065"
                     /old_locus_tag="STBA_50790"
     CDS             23814..24134
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016908785.1"
                     /locus_tag="STBA_RS25065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_50790"
                     /product="50S ribosomal protein L21"
                     /protein_id="WP_077061399.1"
                     /transl_table=11
                     /translation="MYAIVRTGGRQQKVSVGDVIEVDRMASEVGDTVELSALLVVDGET
                     VTSDPWVLAGVKVRAEVTDHHKGDKIRIQKFKNKTGYRRRMGHRQLHTQLKITDIPAPA
                     SK"
ORIGIN
        1 cctgcaacac ggtgttctac ggcatcgccc accgcgagtg gcagaacgac ggcggtatcg
       61 accccgtcga cgatcccgac gactggctgt tccgcaccgc gcacgacttc ggcctcggca
      121 cccccaccgg catcgacctg ccgaacgagg cgcccggccg tatcccggac cgggactgga
      181 agcaggagta ctgggagctg aacgaggaat cgtggtgcga gatcgccgat tccgaccgtg
      241 acgactacgc cgcgcagatc gcccgcgaga actgcaccga gggcatgaag atgcgcgccg
      301 gtgacatgct caacttcagc atcggccagg gcgacgtgct ggtcaccccg atccagctgg
      361 cctccatcta cgcggccctg ggcaacgggg gcaccctcta caccccgcag gtgggccgcg
      421 cggtgatcgc cgcggacggc gaggtcgtcg aggagttcga gccgcaggcg gcgggcgacc
      481 tgcccgtgga cgaggcgacg atggaaaacc tgcgggacgc caccgcgggc gtcgtcaccg
      541 gcgacggcag cgccgcctgg cgcttcggcg ggtggccgca gaacgagatt ccgctgcggg
      601 ccaagaccgg caccgcggag gcgtcggggg acaggcagac cacgtcgtgg ctggccacct
      661 actcggacga ctacacggtg gtcatgacca tcgcccaggc cggcaccggc tcgggcgcct
      721 cgggcccggc cgtgcggaac atctgggagg cgatctacgg cgtctccggc ggttccgtca
      781 acgaggacgc ggccctcctc cccgagccgc accgcgacct gccgccgatc gacgagaccg
      841 gcgccatcgt tcccgagcag gacgagaacg aaggcgagga ggtggcaggc ggcgaagggg
      901 ccgacggcgg cgaaggggcc gacggcggcg aaggggccga ccaggccggc gatcccgccg
      961 cggagccggg ccaggacgtg cggcagggcg gcgtgcaggg ctcgccgccg ccgggacagc
     1021 cgcaggacgc cgtcgacggc cccgtgggga cggtgacgga ggacctgccg cccgaagtgc
     1081 cgggcagccc ggcgggggag gcaccgccgg gcctgccgcc cgaccggcgg cagaacgagt
     1141 gacgggccgc accacggcag gacgaacgga tacccggtga gtgttcacac cctgaccctc
     1201 ggcgggtcgg ccgcgcgcaa gagcacgtgg cgccggctcg ccgcccgcga ctcggtggcc
     1261 cgccgcgtcg actggatact gctgctcgcc gcgctggcgc tgtccgtgct cggcgcggtg
     1321 ctcgtgtggt cggcgacgcg caaccgcacc gagataaacg gcggcgaccc ccagttcttc
     1381 ctggtcaggc agggcataaa cctggccgtc ggagtcgcgc tcgccatcgg cgtcatgtgg
     1441 ctggggcacc agcggctgcg cagcgccgtg ccgttgttct acaccttctc gctgggcgcg
     1501 atgctgctgg tgttcagccc gctgggcacg gagatcaacg ggcagcgcgc ctggctctcg
     1561 ctcggcgggt acaccctcca acccggcgag ttcgccaagg tcgccgtcgt gctcggcatg
     1621 gcgctgatac tcgcggccca ggtggacgcg ggggaccgcg actacccggg cagccgtgcc
     1681 gtgttccagg cgctcgcgct ggccggggcg ccgctggcca tcgtcgtcat cgacgacatg
     1741 ggcatggcca tggtcctcgg catgatcgtc ctcggcgtac tcctggcctc cggcgcgccg
     1801 ctgcggtggt cgatcggcct cgtcctggcc gggatagccg cggcggtgct ggtctgggcg
     1861 ctgggcgtgc tcgaccagta ccagctcgac cgattcgccg cgttcgccga cccgtcccgg
     1921 gacccggcgg gcgtgggcta caacaccaac caggcgagaa tcgccatcgg gtcgggcggc
     1981 ctcgacggca aggggctctt ccagggcacc cagaccaccg gtcagttcgt gcccgaacag
     2041 cacaccgact tcatcttcac cgtcgccgcc gaggagctgg gcttcatcgg ggcgggcggg
     2101 atcatcgtgc tgataggcat agtcctgtgg cgggcgctgc gcatcgcccg cggcgccacc
     2161 gacctgtaca gcaccatcat cgcggccggc atcgtcgcct ggctcgcgtt ccagtgcttc
     2221 gagaacatcg gcatggccct gggcatcatg cccgtcgcgg gcctgccgct gccgttcctc
     2281 tcctacggcg gcacgtcgat gttcgccgtg tgggtcgcca tcgggctgct ccagtcggtc
     2341 cgcatgaaac gcccgctctc cgccgcctga aacgtccgtt tgcgccgggc tcctcctgcc
     2401 tactcgtagg ggcgggacag caggcgacgg acgaggacgg gcatgacgac aaaacaggaa
     2461 atcagcagca cgaaggaaac cgagcgcaag tatgaagggc ccgtgccgct gcccgaactg
     2521 gcgggcaccg ggccggtgca caccacacgc gaccccggcg gcctgctcct ggacgccgtg
     2581 tactacgaca ccgccgaccg gcgcctcgcc gccggcggcg tcacgctgcg ccgccgcacc
     2641 ggcggcgccg acgacggctg gcacctgaaa ctgccgctcg gcggctcctc gcgcgaggag
     2701 atcagggccc cgctcaccga ccagctgccc gactcgctgc tcgcgctgtt gcgcgcccgc
     2761 atccgccggg agccgatcgg cccaatcgtc agcctgcaca ccgaccgccg ccggcggctc
     2821 ctcctcgacg tggagggcac cgccctcggc gaggtggccg tcgacatggt caccgcccgg
     2881 cgcgacgggc gcaccgcgga gtggaccgag atcgaggtcg aactggccga cggtgccgac
     2941 ccggccgtcc tggacgcggt ggaggaacgg ctggccgccg ccggtctccg gccctcaggc
     3001 ggcgcctcca aactggcccg cgccctcgcc gagaccgccg aggccaccgc ctgggcggcg
     3061 cccgacgccg cgggcggcac cgcgggcggc gacgtcctgg cctacgcccg ccgccagtgg
     3121 gagatcctcg tcggcctcga ccccgcggtg cgccgcgaac ggcccggctc cgtgcaccgc
     3181 atgcgggtcg ccacccggcg gctgcgcagc tgcctgcgca gccacggcaa gaccctggac
     3241 cgcgcggcga cgaagccgct cgcggaggaa ctgcgctggc tcgcgggcga actcggcgtc
     3301 gaccgcgacc gcgaggtgct cgcggagcgc ctcgggacgc ggctggccga gctgccgccg
     3361 gagctggtgc gcggcccggt gccactgcgc ctggcccgcc gcgacggcat cgcgcggcag
     3421 gcgtccgggg ccggcgtcac cgccgccctg gacagcccgc ggtacctgtc gctgctcgac
     3481 accctcgacc tgctgctcgg cacctcgccg cccctgaccg acgcggcggg gcggccggcc
     3541 gccaaggcca tgacgaagac gctgcgccgc gagggcgacc gcctggcgcg gcggctcgac
     3601 gcggccctgg ccgccgagcc ggggcccggc cgcgacgccg ccctgcaccg ggcccgcaag
     3661 gccgccaaac gcgccaggta cgcggcggag gcggcccggc ccgcgctggg caagaaggcc
     3721 cgccggacgg gcaagcggtt caagcgcgtg cagcaggtgc tcggcgacca ccacgacagc
     3781 gtggtcgcca gggccgcact gcgtcaggtc gcggcggagg ccgaggcggc gggcgagccc
     3841 tcgttcacct acggggccct gcacggccgg gagaccgggc tggccgcggc cggggaacgg
     3901 gcggcgggcc gcttgcgggt acgctgaatg atccagccca caaccgccac cgccctccca
     3961 gaaggacgcg agcccatgcc tgtcgagtcg gtcttcccgc gcctggaggc cctcctcccg
     4021 cacgttcaga agccgatcca gtacgtcggt ggtgagctga actccaccgt caaggactgg
     4081 gacgcctgcg acgtccgctg gtcgctgatg taccccgacg cgtacgaggt ggggctgccc
     4141 aaccagggcg tcatgatcct ctacgaggtg ctgaacgagc aggagggcgt cctcgcggag
     4201 cgcacctaca gcgtctggcc cgaccttgag gagctgatgc gcgagcacgg cgtcccgcag
     4261 ttcacggtgg acgcgcaccg gccggtctcc gcgttcgacc tgctgggcgt gtccttctcg
     4321 acggagctgg gctacaccaa cctgctggcc gccctcgacc tggccgggat tccgctgtcg
     4381 gcgcgggagc gcaccaccga ccacccggtg gtggtggccg gcgggcacgc cgcgttcaac
     4441 ccggagccca tcgccgagtt catcgactgc gcggtcgtcg gcgacggcga gcaggccgtc
     4501 ctggacatca cccgcatcgt gcgcgcctgg aaggccgaag gccgcccggg cgggcgcgcg
     4561 gagctgctgc tgcgcctcgc gcgcagcggc ggggtgtacg tgccgggctt ctacgacgtg
     4621 gagtacctgc cggacggccg gatctcccgc gtggtgccca accggccggg tgtgccctgg
     4681 cgtgtcgcca agcacaccgt gatggacctc gacgagtggc cgtaccccaa gcagccgctg
     4741 gtgccgctgg cggagaccgt gcacgagcgg atgtcggtgg agatcttccg cggctgcacg
     4801 cgaggctgcc ggttctgcca ggcgggcatg atcacgcggc cggtgcgcga gcgttcgatc
     4861 accggcatcg gcgacatggt ggacaagggc cttgaggcca ccggtttcga ggaggtcggc
     4921 ctgctgtcgc tgtcctcggc cgaccacagt gagatcgccg acgtcgccaa gggcctcgcc
     4981 gaccggtacg aagaggacaa gatcggcctc tcgctgccgt ccacccgcgt cgacgcgttc
     5041 aacatcgacc tcgccaacga gctgacgcgc aacgggcgcc gctccggcct cacgttcgcc
     5101 cccgagggcg gcagcgagcg gattcgcaag gtgatcaaca aaatggtctc cgaggaggac
     5161 ctgatccgca ccgtcgccac cgcctacggc aacggctggc ggcaggtgaa gctgtacttc
     5221 atgtgcgggc tgcccaccga gaccgacgag gacgtgctcc agatcgccga gatggcgacc
     5281 agggtcatcg cgaagggccg cgaggtctcc gggtccaacg acatccgctg caccgtctcc
     5341 atcggcggct tcgtgcccaa gccgcacacc ccgttccagt gggccccgca gctctcggcg
     5401 ccggagaccg acgcccggct ggccaagctc cgcgacgcga tccgcgccga caagcggtac
     5461 ggccgttcca tcggcttccg ctaccacgac ggcaagcccg gcaccgtcga gggactgctc
     5521 tcgcgcggcg accggcgcgt cggcgcggtg atccgcgcgg tgtacgaggc gggcggccgg
     5581 ttcgacggct ggcgggagtt cttctcctac gaccagtgga tggcctgcgc cgagggggcc
     5641 ctgaccccgc agggcgtcga cgtcgcctgg tacacgacgc gcgagcgcgg ctacgaggag
     5701 gtcctgccgt gggaccacct cgactccggc ctggacaagg actggctgtg ggaggactgg
     5761 caggacgcac tggacgagac cgaggtcgag gactgccgct ggaccccctg cttcgactgc
     5821 ggcgtgtgcc cgcagctgga caccaagatc cagatcggcc ccacgggcaa gaagctgctg
     5881 ccgcttcagg tcgtgaagtc aggcgctgag ccgcgttgac gcggggaggg cgaaccgggg
     5941 ttcgccctcg ccgccgttcg gcgtcgacgt gagttcacga tcgttctggc gacgtctccg
     6001 ttccggagaa cgtgccgttg cactcgcgct ggagtgcgat gtcgttccac atcggatggt
     6061 gtggagcggc gttggagcac acgatcgtgc cccatgcccc ggcccgcgcg ctgaggcgga
     6121 cggcctcccg gcagacctcc gcaccgacgg gcccttcctc gaagttgccg ctcagcgggg
     6181 tgcagccgat ccagccttcg ccgaagacca ggggaatccc gcgtccggcg cactgatcgg
     6241 cagccgcgga gatccaggtg tccagggtgc gcagcatgga cctgcggtgt tcgccgtagc
     6301 gttcgtacag gaatcggtcc catgcctcgg cgtcgcacca gtcgtgcacg tagatctcgg
     6361 gcttgccgac gatcgtggcc ttcagccgcc attcctcgcc ggcgggcgga cgccactggc
     6421 cgaacgtcgg ggcgccgggg cgccggggcg catgaggtcg gcacgggcgc gttcctcgtc
     6481 gaatccgccg tcggtcgagc gcaggccgta gccgaccacg agttcgtcga gaactccgta
     6541 gacatagggg tggaagacgc cgacgtcgat gttctcgggt atgccgcgga acgcgtccaa
     6601 cggtacgcgg gcgtagttga ccgtgacggg gacgtcgggt tggcgttcgt ggaagcgggc
     6661 caggccgcgt tcgaggcgct cccgcagctc cacgacggcc ggttcgcgtc ctggcagtcc
     6721 ttccgtgagg tatccgccct ggacctcgtt gtgcagttcg acgaacgcga tcacctcggc
     6781 gagcccttcg gcttccgcga gttcgtaagc gtcggcgagg gcgtcggcca gccgggtggg
     6841 gcggtcctca ggttcgacgg ccatgagcgc gtcgaaccat cgtcgatcac cggcgaagga
     6901 actgctctgc tggtactccc agctgcgatc tccgagaggt ccaggaacag ggactcggcg
     6961 agctctccct tcatcacccg ggggaactcg gagctgatga tgcccagcag gtcgggcggg
     7021 gagccgtcgg ccatgaactg tgtgatggtg cgcgtcagca ggtcggagcc ggaggcggcg
     7081 gtcacctcaa gggagggtgt gtacgccgac ccgcgcatga tgctccggtc gctcagggcg
     7141 gcctggaaag ttgcggtgta actcgggtcg tggaaccaca gcttgagacc gaccgggccg
     7201 tccgtcaccg gtcgggccgg ggacgcggtc gcacacccgg tggccagcgc ccccatcccg
     7261 cccagcacgg cgaggaagcg acgtcggctc agcccgctca cggcgcaccg atcccgacag
     7321 cggcacggta gacggggacc agccgggctt cccgcagccg cagggtgacc tcgtccgggc
     7381 gttggtggtc gggcacgtgg atcttcgcgg cgggatcgaa cgggagcagc cgcaggacca
     7441 actccgcacc gtcctccagg gccgctcggt gccgggtgag gtcgatctcc cagggggcac
     7501 cgttccagta ctggtcggct accggagtgc cgccgatctc ggcgcgggcg acgtccccga
     7561 cccagtcgag ccgcagcagc agtcggtggg ccgcggtgaa ggcttcatgg tcgaactcga
     7621 cgcgatgggc ggcggcgagg gcgtagtcgg cgtcggtggg agcggcggcg cgcttcagcg
     7681 gaccgccgat acgctgcggc gccgggcctt tggccgcggc gagttcgacc agcgcggcct
     7741 cgggcacggc cgtgggtgcg tccacctcga accgtgcgaa gatcccgctt tccccggtgg
     7801 cgcgcagcct gagccgcgag gtcgccaggt ctcgcggggc gacggtgccg gtcggtgcgg
     7861 gaaggacgag cagggtgccg ccggcgggcc cgctctcgat gtgcaggtgt cgtccgtcgg
     7921 gcacgacgtg gatgccgtct ccgacgagca gccgacgagt tccccacagc tctccgaccg
     7981 tggtgtggcg ggcggtgtgc tcatcgagga ccagcagccg cagcccgtcc agccggatga
     8041 gcgcgtccgt gccggggtgc ggcacccgga ttcgggtgcg gtcggcgccg aggtcgtcca
     8101 cgatgacgcc cgggccctcg accgaggccg ggtcgacacc ggtgaggacc agttcgaccg
     8161 ggatgccggc ggtgcgggtc agcacgacca tgtcgtccag gacggcgacg agttgggccg
     8221 tggccgactc cagggtcgcc gcgccgggca gcggccagcg gaacggccac gcgaagtagg
     8281 cgcctgaggg gatgtcggcg ggctccgtgg gcagttcgag cggtccgtcc gcggtgtcga
     8341 gacggaaccg gacggcgcgg tgcgcggcca gtgtctcccc gccgggctgg tgcgtgttga
     8401 cgaacagcat gccggaggtg ccgtcgctgc gcgcggccca gcgcagtgtc tcgcggtcgt
     8461 cgaggtcccg ggggctccgg tcgggcgcgg cgaacggcat cggggccagg cgttcgcccg
     8521 ccgcggccag gaggtggtgc tggaggcgga gcagtccgta ggcggggcgg acctgtccgt
     8581 actcgccgag gggggcttgg aagtcgtagc tgatgaccgg cagatcgttg gggtagccgg
     8641 tgtcggtcga ctcctgcatg gtggtcgcgg cgtcggtgac gtgggtgccg ccctggtaca
     8701 tgtagtagcc ctgccaggac gatccgctgc cgatcttggt gagggccagc gcggccacgt
     8761 cctccggcgg gacgaggggg cggcggtggt aggtcgcctg gacgccgccg ccgagttcgc
     8821 aggtcgcgta cgggtagcgg ccggggtcgg ggccctgccc ggcggtgggc cggcggcgga
     8881 ggtcggcgcc cacggtgtgg tcgtcgcgca gcgcggtgaa gaagaagtgc cgcctgttgt
     8941 gccgggccca tcccggatgg gcgtcgtccc acggcgcctc ggggtagccc gcgtacacag
     9001 ggaggaattc gtcggcgggg agctgcgcct ccccccaggc cgtcgcggtc cacagcggcg
     9061 gggtgatccc ggcgtcctgc gccatccgct tgagggtgcg gaggtgttcg ggctggtcgt
     9121 acagctcgtt ctcgatctgg acggcgacga tcggcccgcc ctgggtgtgg tggaggccgt
     9181 cgagttccgc gccgatccgc gtgtagtagg gccggaccag gtcgaggtag gcggggtcgt
     9241 cggtgcgggt ccgggtgccg gagtgctgga cccagtccgg gaagccgccg tagcgggctt
     9301 cgccgtgtgc ccaggggccg atccgcacca cggcgtccat gccgtacgcg ccggtctgct
     9361 cgacgaacgc gcggatgtcg cggttgccct cgaaccggaa ctcgccctgt tgttcctcgt
     9421 ggtggtgcca gaacaggtag gtcgcgacga cgccgatgcc cccggcccgc atgttgagga
     9481 gccgctcccg ccacgcctcg cgggggcagc gggagaagtg catctcgccc atgaccggga
     9541 accagggacg gccgccgcgc accaggtggg tgctcgtggc ggcgatccgg tccggttgcc
     9601 cctcgggttc gcccatcctg agatggccgc cgaacgactc cgcggacggg cgcagggtca
     9661 ccttgtacac catcgatctc cttgcctcgg cgccggaccc gggtcggccc gtccggcagg
     9721 ccggcatcgc caatggacgc aacttaaatc ataatttctg aatagtgaac ctcctggggt
     9781 gccgagcttg gcatggccgc accgaaggag gcgcggcgca gggcggcggt gcagagggga
     9841 acgccacgcg cacgcccgcg cgtgcgcgcg tgcgcgcggg cggtcggggc gacgacgggg
     9901 cggttgccac ggacggcgtt gccggtcgga agccgccctg gcgcgcggag gcggacggcg
     9961 tggagcgttc cggcgcgccg gaaaatcggt ccgcagccgg tcagttgacg agcagggccg
    10021 cgtcccagcg cggtggcgtc ggcccgcgcc ggtggagaac gagggccacg cccgcggaac
    10081 cttcgaggaa ggtgggggcg tcccagatgg ccggtggcag ccgtcggcgt ccgcgcgtcg
    10141 ggtagccgaa cgcggacgcg ggctcgaagc gggcgcggag gcggtcggtc agactcgccg
    10201 cgtgctccgc cagtatcggg tcctgggcgt catgggcgat cacgcgggtg aggtgggcct
    10261 gcccggcgag gccatggcac aggcccgggt cgtcgagccc ggcccggcct tccggacggc
    10321 gaaggaccgc gtgcatggcg tccaccgcga cccgcggcca ctcggtctcg cccagtgcca
    10381 ggcccgccag ttgcagggcg cgcgcgatcc ccggggggcc gtagcaccag ctcgggcggt
    10441 gtggctcgtg gcgcgggcgc cggcccgcgg cctcgtccgc cgccgagacc atcatgggcc
    10501 agtacgggcc cgcctcgtcg tcctggcgcc agctcagcag ccacttggcg gcgcgccgga
    10561 tggcggcgtc ctggccgggc acccggatgc cccgcgacca gcacagggag agcaggacca
    10621 gcgggcccgc gatcccgtgg gccaggccca cgtcgatcgt gtcgccgtcc gcttcctggc
    10681 ccggccatgg cgggcccgcc cagccgggca gcgtgcggcc ctcgtgcact ctcggttcgg
    10741 tgagggcggt caggtagcgc agggcgtcgc ggacggcctg cggcccggcc gggtcggccg
    10801 tcccggccgt ctccgtcgac cgggacggaa cggccgggcc gtccaggaaa tagcgggcga
    10861 ttccggtgac gccggtcacc gcgtcgaagc gttccctcgg gaccagttcc ttgccctcgc
    10921 tcatcctggc ctcctccagg gcgaggaggc ggcccagccg ttcgcggagg aacgtgtcca
    10981 gccgctcgcg gatggtggcg tagtcgccgg gcttccggac ggccgccctg atcgcgaagg
    11041 ccagccccgc cgctccttgg tagagcccgg ggccgaggcg gccggccacg gggagcaggg
    11101 ttttcgcggc gtcggtcagc cgggcgtggg cggcccggcg gagctccgga tcgtgcctgc
    11161 tgagttcggc gagcagcagg gccgtgccga tggtgccgtc ggcgaggccg agcggctggc
    11221 gggcgggcgg agtccacgcg ttcgcccgtg ccgcgatctc cgccaccacg gcttcgtcgc
    11281 tccaggcgct caccgcaggt gctcccggcg cgcctgctcg gtttgcgcca tgccgcgggc
    11341 gaccgcgaag gaacgctcct ccgaggtgcg gttggcgccg atcagccggt tgtggtgcat
    11401 gtgcagcact ccggccagca ccgaacgccg ggaggccgcg gggaagtccc gcagcgccgc
    11461 ggcccgttcg gccaggccgg ccgggtcggc ctggccggac gcgctggtgc cgggcggcgg
    11521 ggcggtgccg agcaggccga gtgccgcgtc gcggtgttcg cggaagtacc ggtggtgctc
    11581 ctcctcacgc ggcatggcga ggaaccaggc gggccagtca ggaccgtgga cctgccgggc
    11641 gatgtcgacg tagtgtcccg ccgcgagtac cggcggcggc gtggtcacgg tgcccgctga
    11701 cagggccgcc agttgcccga cgacggtccg gctgtcgtgg tggaagaacc gttccgcggc
    11761 ggcgatggcc ccgggcccgc cgtaacggac ggtctcgggc tcgtaccggt cgacggccag
    11821 ccggccggcc agccgccggc ggtacaggtc gtcggcccag tcctgcaccg cgggtgcgac
    11881 atcggagagc agcgctcgcg gatctcccgg gaaccgcagc cgcagatggg gttcggggtc
    11941 gatgtagcgg atgaagaacc agtgcccgcc gccgtccggc aggttcgcca gcagccgggg
    12001 cagatgcgag gccagcacct cgttctgccc ggccgtggcg aggtacagct tggcgtagta
    12061 ccactggcgg tgacggttcc cctgccgggg ggccgggccg cggcgcgcca tgccggcggg
    12121 cgccctggcc gtcccggcgt cccggctgtc ccggccgtcc cggcctcggg gcaggacggg
    12181 gatgagcacc tcgctgcggt acgcgccgcc ctcgtcgtcc cgcagccagt gctcggcgta
    12241 ccccgcgtcc tccagcgtct cgtacgccac cgtccccggg tcccgggcca gttggcggcg
    12301 caacagcgtc cggtgcagcg gggccgacag gtcgagtacc acccgcagat cgaccgttcc
    12361 cacgttgacg cgccggggca cggcccagcg ggcccgccac gcgtccaggg cgcggcccca
    12421 ctcctcgtcg gacgccgagg agtcggtcag cgccgggtcg gtcatcttcc agcgcgcggg
    12481 agtcagaacc gtgcggccgt ggcggacccg gggcagacgg gtggcggagc cgatggcccc
    12541 ccagtcccac acggaccagg tcggacggcc catcgacgag atctcgcgca gcaggcggac
    12601 ggcgtcggag gtgaagccca tggacagcac ggtggcggta tgcgcgacga gttcccgccc
    12661 ggtggccgcg tccacggcga acagccgctc ctcgtcggcg gccagggcga cgtcccgcgc
    12721 gcctcgcaca cggcccccgg acgacgggtg gtgggggaac gagccgaccg tcagccggtc
    12781 cggccagcag gcaagcgcgc gcgtgacgtt cgcggcgccg ggcagcacct ggaagtccag
    12841 gctgaccggc gtggcccctt cccggagcgt cgtcgccatg gcgtcccgcg ccagtgccgc
    12901 caccggctcc tggtcgtcga agagataggc gaagcggccg aacagggcgc ccggggtcgg
    12961 cgagccggtg gtctgggaga ggatcagccg gaactctccc cgggccaggg cctcctggga
    13021 cacggcggtc acctgggcgc acagctccgc cggggtcggc gcggtgtcgg gcgcggcgtc
    13081 ggccagccgg ttcagcacgg cgtctcccag gacgatctcc ccgctccccg cggcggcgga
    13141 cagcaccaga tcggtcagca ccgcgtcgcg cgccgggcca cggtccgcgg cggcgggcgc
    13201 cacgcgccgt tcgccgcccg gattctcgta gccggccggc gggccgagcc cggagtgcgg
    13261 gtcgagaacc tccagcagcg gtacggcgtg gccgacgccg taccgttcca cgaacgccct
    13321 gtgatagtcc gccagatggg gctttcgctc gtccttggcg gatgcccgcc acagcgccgt
    13381 cgcggccgac tcggcctccc gcgccaccgc ttcgggcagg atcacctcgg cgtcgatccg
    13441 caggtcggtc tggaggaggg tcccgtcgtg ccggtgcagg tcccgcaatg cccgctccgc
    13501 ggtgtcccag cggcccgttc ccgcgccgag cggcgcgccc gcgcagtccg ccagcacctt
    13561 cgcgatgcgg gcgaccgcgt cctccttctc ccggtccgcc accgaggcca ggacctcacg
    13621 cacgtacagc agcgggtcgg cccgggcgag gggcgggcgc agttcggtca gcaggaagcc
    13681 gcgccggacg aggtccgcca gcagcccgtc caccttgccg gccgccaccg cggggaacgc
    13741 gctggtcagc cgctcggcga tctccccgcc cgtgcacggc tgttcggccg cctccagggc
    13801 cagccgtacc gcggcggtgt ggcgcacgga gacctctttg gtacgggccg ccgccgcgcg
    13861 gccctcgtcc gtcacggggg tgaacggcag aacccaccgg tcgccgcggg cgaagcccag
    13921 gtcgttggtg accacccgca gtctgcgcag cagcgccggg tcgcgttccc aggcggagag
    13981 cagccccacc agccagtcgc cgtccggccg caccgcgacg cggtgccgct cgccgacgcg
    14041 tgcccggcac gcgtccccga aggcgacggg cgccaccccg gccagcaggc cgaacggggt
    14101 ggggcggccg gcggcccgca gcacgtaccg ggtcgttccc agcgtgagct tgcgcagcgc
    14161 cgccggcttc atcggctcac ccgcctgaag tgtgcggatg gcgcggtgca gcgacgggct
    14221 ggagagcagc agcgcctcca ggacccgttc gtcggcgatc agcgtggcaa cgtagcgttc
    14281 gacctgtgcg cggtcacgcg ggtcgagccc ctcggccgct gcgacggtcc gctcgaccca
    14341 ggagtacggc agcagcggga tgcgcagcat gccgggaccg gcaaagcgaa aagaaacgtc
    14401 gtcccctgac aatggaccgg attctccctg cctgtttttc cgcgtctgct tctgcttttc
    14461 cgcgcctcgt gcccgcccgg cggaagtgtg gtgcgccaca tggtgaaagg cacgggcgcg
    14521 gagccggtga acggcccgcg cccctgccgt catggctcaa tcacgaacag aagattgccg
    14581 tagtcgcggg aatacagacc gagcagtcac tcgtgtaagg gccgttgggg aaagagaccg
    14641 tcttcgcctg cgcgaagccg tcaccgtcct ccaggtcgct cagctctatg cggatgtcga
    14701 ggtcgaagtc ggaatcggtg agttcggtgg tcggttccgc gacagaggtt gacatgcgat
    14761 tcctttcacg gtgagccggg ggtccggcct gggaatgtgc cggccctcag cgatgaccgt
    14821 gacactgtat gaggcatgtg acgggctttc aagagcgtac taagggccgg tacttgctcc
    14881 gctgcggtgc cctatgcggc gttttcctgg gtcatgccct taatctgccg gttggggctt
    14941 tccttgctcg ttgcggcgcg tctctcgtga caggtgaacg cggccggtga attcgggagg
    15001 cgccgcgtca cggcgcgggg tgaatgggcg cggtctcgtt cacctgtcgt gtttcccgag
    15061 gattttcgaa gggaattgga tgtgccgggg tgcccgtttt cggcgcgctg ccgcccggct
    15121 gccgtgcaga gcgggcggaa tgcgtcggcg tccccgggcc cgccgagatg cgggcgcgtc
    15181 cgttcatctt ccggaagtac ctgtccgcgc ccggtttcgg gcacggcccc ccgcacatcg
    15241 tccctcatgc cggagcggcc cccgccaccc cggcgggcgg tccgtcgcac ccgcgccggg
    15301 gtgccccttg gcggggtgcc gttggcgagc ggtgaagcgg cccacaagta atctgccggc
    15361 agcttcctga gcgagggagg ggtgccgtag cgcacgtcag gacagtgccg cggcgcgctg
    15421 gtcgagctcg gctgcggcgg gtattccgtc aagccgggcg aggcgggcgc acatgtcggt
    15481 gacggcctcg gtcaccttga ccgagtggac gccggcggcg ctgttcagga agtggatcac
    15541 cgaccgctgc ggggcggacg tcctggactt catccagcag ctccacgccg agcacgaggt
    15601 gctggccggc cccaccgcgg cgaacaccga ccgccacctc gcggccctga cgacggtgcc
    15661 gtggctgctg cacgccgccg tcgccgccaa gatcgtcgcc ctggaccacc tcaccggccg
    15721 cgcggccgaa tcccccgacc gcggcgcatt ctggcaggcc cggcccgcct tcgtgcggct
    15781 gctgccctac ttccgtcggg tacaccaggt gggcatgagc acggcccacg gcgaaccgct
    15841 ggcccgctgc cccacctccg ccggggagcc gtagccccgg ccgcgcaggg gcgtgcggga
    15901 ggcagtcgcg ggactccggg cggggtgacg gacccggccc ggccctcggg cgtcggacct
    15961 atcggtgcgc gcccgaaccg cgccgcgccg gcccgcgagc gtccggcagg cggccgttcc
    16021 gcctcgcggt cacgcccgct cgtcacccgc accacgcagg gacgcgcgtg gcacacccgc
    16081 cagttcggcg gtttcgaccg cggcccggtt gcgagccgcg tccaggcctt cacgtgccga
    16141 ggcgtcgacg tgaacgcgcg acgccgggtc caagggcagg acgcggatct ccacaccgtg
    16201 ccgagcggcc gcgtccgcga agcggcggag tccgatctcc cactcggggc ggtaccagaa
    16261 atgatcggcg acgagccggc cgccgatgtg ggcccgggcg gcgtcgcccg tgtaacgcgg
    16321 cctcagccgt acctccccgt cgcctgccag agccgatgcc ggaacggtga cgcggtacac
    16381 ggcggccttg ccgaagcgtc acaaagcggc gcacgccgag gtcaccgtcg aagcggaacg
    16441 tgccgcgctc gttctcgtgc tggttccgga acaggtaggt cgccacgaga gacgaccgtc
    16501 ccggagcggg ctccggctgt cgacggtcag tgtgtgcgac gcggtggttg aactgcccat
    16561 gggcaggtgc cccatcaggg gcgcggctgc ttcgtgaaca tgcagagaca acatgacagg
    16621 cggctactgc ggggcggcgg ctcggtggag cgcgttcatc gtggagggag ccacgggcag
    16681 cgtcaagatg tattcataat taatgcctac tgctagggtg ggtgggccag gcctccacat
    16741 ctggggcccg cgcagacccc gaggagagac ccgccatggc gtcgtacacc ggaagaggcg
    16801 ttcacgggca ggtcgtccgc gtcctcggcc tgcgtatcgt cggcggtgac ttgcccgagg
    16861 gagccactct cgacatgcgt ggcctcgggg aagaactcga cgtcagcctc accgtgatgc
    16921 gcgagtccat gaaggtgctc gccggcaagg gcctgataga cgctcgccag aagcgtggaa
    16981 ctttcgtcag ggagcgcagc aattggaacc tgctcgacgc ggacatcatc cgctggcagg
    17041 tcgagagcgg cgccggacag cgcctcatgc gtgacctcgc cgaggtgcgc gcgatcgtgg
    17101 agccggccgc cgctcaccgt gcggccctca accggacaga aggcgatctg cgagcgctgg
    17161 agaccgcgct cgacgcgatg acccatgccc gcgctcactt ctccgcggac gccgccgagg
    17221 ccgacgccgc attccaccgc gccctgctct gtgccaccgg caacgagatg ctcgcgcgca
    17281 tggacctcct ccttgagccc gggctacgcg aacgcgaccg ggtcgtccac tcccacgatc
    17341 aggccaacga ccccgtcccc agccaccggg ccgtcctcga cgcgatccgc gaccaggacc
    17401 ccgcccgcgc ggagcttgcc atgctcgacc tcctcgccaa ggccacccac gacctcgacc
    17461 ggatcaccgg cagcgtctcc gcggcgcacc agccctgaca cctcttccgc cctcaccgac
    17521 gggcctgcgg tgcggcgcga ggcccggctc accggccctg ccgtcggggc cccttcgcgt
    17581 tctcctcctg gctcccgctc ccgcgcgttc tgcccgctga gcctgtgccc ggtctgtccg
    17641 ggcacacgtg agcaccgtta cctaccggtc taccgggtcc aggtccatgc caagggccgc
    17701 gagcacgagg tgaaagctct gtccccataa gcggtggtgg cgaagcgtga ctggcgtcat
    17761 tggcgccgcg tgcggggtgc cgggtggaac gcgtcatcgg gctccacggc gttcggcagg
    17821 acatcgccgt gccgcggacc caccggccgg tgggcatcag ccaggagctg gcgatcgcgc
    17881 ggtacgagga cagctgtcgg ctctgctgcg tccgcggccc tggactggcc gagcagctcg
    17941 gccgaaggcc gcgaggggac cgggagccgc ggggcgcggg ggcccgtgta gggtcgcctg
    18001 atccacggcg gggcggccgc cgtccccgct ccgggcacgg ttgggggcag gacggtcgtg
    18061 atggtttccg ggtcttggaa gaagccgccg gccgccggcc gtggccgggt tgccgcggcg
    18121 ggcggtgcgg cggacgatga ggccgtgccc cagctcgtcc agcccaccac cgcggtccac
    18181 gcctcgtttc tcgaagcggt ggaagagttc gaggcggagg ggcgcggcac cctggaggac
    18241 aactccatgc tgggccgcga catctccgtc ttcggccgcc gctggcagga ccccgaaacg
    18301 ttcgcccagt acgtcgcgga gaacatagcc gcggcccgcg acgacaccct gccgccgccc
    18361 ggcttcgtgc gtgccacgat cctgtggtgg gtcgaagggg acaccttcct cggccgcctg
    18421 tccatacgcc accggctcac ccggcggctg ctcgactggg gcgggctcat cggctacgac
    18481 gtgcggccct ccgcgcgccg ccgcggccac gccaccggca tgctgcgcgc gtccctcccg
    18541 ctcgcccgcc ggctcgggca cgacccggtg ctggtgacct gtgaccacga caacgtggcg
    18601 tcacggaagg tcatcgaggc gtgcggcggg gtcttcgagg accggcgggg ggagaagctg
    18661 cggtactgga tagccaccgg tgggacgtaa cctggaagta agcaacggcc cgtgaccggg
    18721 ccggagagtt tcgtacgagg gactgaagac cactgggcaa gcgacagccc gtaggcccgc
    18781 cgcccgctcc cgcggtgcag cgcatccgga tgcggtatac gaagcggggc cgcctgcggt
    18841 tcaccagcca ccgcgatttc cagcgcgcct tcgagcgcgc cctgcgccgg gccggggtac
    18901 ccatggcgta ctccgcgggg ttcaccccgc accccaaggt ctcctacgcg aacgccgcgc
    18961 cgaccggcac ggcgagcgag gcggagtacc tggagatcgc cctgaccgag cggcgggacg
    19021 tcgaggagct gagagcccgc ctcgacgcct cgctgccgga cggcctcgac atcgtggaca
    19081 tggtggaggc ccgcaccacc gacttcgccg agcagttgca ggcgtcccag tgggagctgc
    19141 ggctggacgg cgtacagccc ctggacgcgg accgcgcggt cgccgctttt ctggccgccg
    19201 aggccgtcga ggtgcagcgg cggacgaaga agggcctgcg cgccttcgac gcccgcgccg
    19261 ccgtcgtatc gctcgccacg gtgccgtccg gaacggcagc aggtgggtcc catgggcctg
    19321 acacccagcc ttgtgcgata ctgcgcctgg tagtacggca ccttacccct gccgtacgac
    19381 ccgacgacgt cctgtccggt ctccgcgcta aggccgacct ggcgccgccg gtccccgcag
    19441 cggtgaccag gctggcgcag gggccactcg atgaggagaa cggcacggtg accgacccgt
    19501 tcgcgcctga ccgcgacgct gccgaagccg ccctgaccag ggccgccgga cagcaggccg
    19561 cggcggcgcc gggggtcacc ggatagcgat gccgttgctg tgccgcagaa cggccggggg
    19621 cctgggagcc actcgggccg ggctgttccg ggcggcgcac cgaccagcag actttcgccg
    19681 tagccggacc cagtggtccg gaaccggcga gtaaaacgac agctctcgag cggcgcccgc
    19741 taggcggtga ggcgcccggg agcgtgacgg gagaaccgcc cgcatgcacg aggccaacga
    19801 atccgtgggg ccgaacggtg ccgagcgcac cggggacacc cccgcggcca ctacgacaac
    19861 ggacaagaac accacaccga gtgacaccct cccgccccgg cgccgccggg cggcgacccg
    19921 cccggccggc cctccggccg cggtggcgga ggaggagagc aggacggacg aggccgagca
    19981 ggccgcgccg cggaagcggc gccgtgtgac gcgcgtcgcg tccgagccgg aaacggaagc
    20041 gcagcaggag ccgcagcagg agccggtggc cgcggaggcg gaggcggagg gtgctgcgcc
    20101 gcggaagcgg cgtcgtgcga cgcgtgctgt gtcggcgcct gagccggtgg ctgaggaagc
    20161 ggtggccgag gagccgcctg cggaggaggc cgcgcccgcg cggaagcggc gtcgtgcggc
    20221 ggccgatgag ccggtggccg cggaggcgga ggcggagggt gctgcgccgc ggaagcggcg
    20281 tcgtgcgacg cgtgctgtgt cggcgcctga gccggtggct gaggaagcgg tggccgagga
    20341 gccgtccgcg gaggaggccg cgcccgcgcg gaagcggcgt cgtgcggcgg ccgatgagcc
    20401 ggcggccgcg gagaccgcgc ccgcgcggcg gcggcgccgc accgcgtccg tgcccgaggc
    20461 ggtggaggag cccgcggccg cggaaccggc cgccgagccc gagcccgagc ccgagcccgc
    20521 cgcgccccgg cgcaggcgcc gggcggcgcg tgcggcgggc gaggcggcgg agacgcccgc
    20581 cgaggagccg cagatcaccg cgcaggagcc ggagcaggcc gtggaggcgc ccacgtcgcg
    20641 caggcggcgg cggtccgcgc gcgaggcggc ggagccggag gccgtcgccg aggtgccgga
    20701 cgaggccgac gcggctgccg tgccggacga gagcgacacg cccctgcccc cggcggtgcc
    20761 ggtggcgacc gccgtgttcc aggcgccggt gttccaggcg cccatgttcc agactccgca
    20821 gcgggccgcc gaggaggcgg tgcgcagcgc cgctccggcg accgggcccg aggaggcgga
    20881 ggggccggag gagcccgagg acgaggacga gcaggacgtc gaggacgtcg aggacgtcgc
    20941 cgaggaggag gacgagtcgc aggccgaccg tccggcccgc aggcggcgcc gcggcggtcg
    21001 gcggcggcgc cgcggggaga ccgcggagcg tgccgcggcg gcagtcgcgg ggaccgacgc
    21061 cggggacggc gacgaggaga ccgcgcccga ggcggaggcc gagccggagt ccggcgcggc
    21121 ggagcccgcg aaggacgcgg acgtggacga ggacgccgac gccgaggcgg aggccgagga
    21181 gcaggcggag ggcggcggtt cctcgcggcg caggcgccgg cgcaggcggc gcagcggcga
    21241 ttcgggcgac ggcgcgggtg gcgacgaccc ggagcgcacc gtcgtcaagg tcagggagcc
    21301 gcgccgcaag cgggacgagg cgaccgagag ttcggacggc gtgcagtcga tcaagggctc
    21361 cacgcgtctg gaggcgaaga agcagcgccg ccgcgagggc cgcgagcagg ggcggcgccg
    21421 cgcgccgatc atcaccgagg cggagttcct ggcgcgccgg gagtccgtcg agcgggtcat
    21481 gatcgtgcgg cagagcggcg agcgcacgca gatcgcggtg ctggaggacg acgtcctcgt
    21541 cgagcacttc gtgaacaagg agcagtcggc ctcctacgtc ggcaacgtgt acctcggcaa
    21601 ggtgcagaac gtgctgccgt cgatggaggc ggcgttcgtc gacatcggca agggccgcaa
    21661 cgcggtgctc tacgcgggcg aggtcaactt cgaggcactc ggcctcggga acgggccgcg
    21721 ccggatcgag agcgcgctga agtccgggca gccggtcctc gttcaggtca ccaaggaccc
    21781 catcggtcat aagggcgcgc ggctgaccag ccagatctcg ctgcccggcc ggtacctggt
    21841 gtacgtgccc gaggggtcga tgaccgggat cagccgcaag ctgcccgaca ccgagcggac
    21901 ccggctgaag caggtgctga agcggatcgt tccggagaac gcgggcgtca tcgtgcgcac
    21961 cgcggccgag ggcgcgagcg aggacgagct gacccgggac gtcgagcggc tccaggcgca
    22021 gtgggaggag atccgcaaga aggcgaagaa gggcaacgcg ccggcgctgc tctacggcga
    22081 gccggacatg acggtgcgcg tggtccgcga catcttcaac gaggacttct cgaaggtcat
    22141 cgtcagcggc gacgacgcgt gggagacgat ccacgggtac gtcgcgcacg tggcccccga
    22201 cctccaggag cgcctccagc ggtggacctc ggacgtggac gtgttcgcca cgtaccgcat
    22261 cgacgagcag ctgatgaagg ccctggaccg gaaggtgtgg ctgccgagcg gcggttcgct
    22321 ggtcatcgac aggaccgagg cgatggtcgt catcgacgtg aacaccggca ggttcacggg
    22381 ccagggaggc aacctggagg agaccgtcac caggaacaac ctggaggcgg ccgaggagat
    22441 cgtgcgccag ctgcggcttc gcgacctcgg cggcatcatc gtcatcgact tcatcgacat
    22501 ggtgctcgaa tccaaccgtg acctggtgct gcggcggctg ctcgaatgcc tgggccgcga
    22561 ccggacgaag caccaggtgg cggaggtcac ctcgctcggc ctggtgcaga tgacgcgcaa
    22621 gcgggtcggg caggggctgc tcgagtcgtt ctcggagccg tgcgtgcact gcaacggccg
    22681 gggcgtcatc gtgcatgcgg accacgtgca cgcgcccggc ggcggtggcg gcggcaagaa
    22741 gagcaggaag cgggcgcggg ccgccgcggc ggaggagccg cagcccacgg ccgcggaggc
    22801 gcagcccgcg ccggccgcgg tcgcggagag cgccgagccg gtggagccga tcgtgccgcc
    22861 ggagacggtg gagcggaacg agccggtcga gcccgtcgag cccgttgagg agccggtgga
    22921 gccgtcgccc gagccgcggc ggcggcgccg cgtctcccgc aaggcgagcg cgcccgccgg
    22981 tcccgcgggg gagggcgcgg tgaccgtggt caccgcggag cagccgtccg ccgcggcgga
    23041 gccggagccc gcgccggagc ccgagccgga gcccgcgccg gagcccgagc ccgcgaccgc
    23101 ccggcggcgt gggagccgta aggtctccgt cccggccggt gcgccgagga gcgcggagga
    23161 gcccgcggtg gtcgtggtca cggccaccga gccggagccg gagcccgttc gggagccgga
    23221 ggccgttcgg gagccggagg ccggcaccgt gtccgaggcg ccgccgcggc gcagggcggt
    23281 gcggcgggcg tccgccccgg ccggttcgcc ggagggcgcc accgaggcgg tcgtgacggt
    23341 cgtgacggcc ggtgcggcga agaagtcggc gaagaagacg gcaaccaagt cggcggccaa
    23401 gaccgcggcc aagaagaccg cgaagaagac ggccaagaag accgccgcca agaagacggc
    23461 gacgaagaag accgcggcca agaagacggc caagaaggcc acggcgaaga aggcggccaa
    23521 ggccacgtcg gcggcggagc agcagcagcc gccctcggtg tccgccacgg ccggggagtg
    23581 agtgcccggg tccgccgccg cccccgcggg ggcggcggcg gacccggctg atttgaccgg
    23641 cttgttgacg tctccgtatt cttggcgatc ggcgtgtcat caggcccgcc atccccctga
    23701 gcactcatcc tcccgcgcgg cgcacgctcg tttccgcgtc cgtccgggag aggccgggtt
    23761 tgccgcccgc tgctggcatc aggggttccg tatcgagcga gggagagttc cgcgtgtacg
    23821 cgatcgtgcg caccggcggc cgtcagcaga aggtgtctgt gggcgacgtc atcgaggttg
    23881 accggatggc gagcgaggtg ggcgacaccg tcgagctctc cgccctcctc gtcgtcgacg
    23941 gtgagaccgt caccagcgac ccgtgggtgc tggccggagt gaaggtccgg gccgaggtga
    24001 ccgaccacca caagggcgac aagatccgga tccagaagtt caagaacaag accggctacc
    24061 gtcggcggat gggtcaccgt cagctgcaca cccagctgaa gatcaccgac atccccgccc
    24121 cggcctcgaa gtaagggact gagcacacat ggcacacaag aagggcgcgt cctccacccg
    24181 gaacggccgt gactccaacc cgcagtacct cggtgtgaag cgcttcggcg gtcagctcgt
    24241 gagcgccggt gagatcctgg tccgccagcg cggcacccac ttccaccccg gcaagggtgt
    24301 cggccgcggc agcgacgaca cgctgttcgc gctccaggcg ggcgccgtgc agttcggcaa
    24361 gcaccgtgac
//
