LOCUS       NZ_LZNS01000001        25177 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4403490
            Orig. end                         :: 4428667
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25177
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="24"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25177
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25177
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15177](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15177)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            272..526
                     /locus_tag="STBA_RS19970"
                     /old_locus_tag="STBA_40460"
     CDS             272..526
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_40460"
                     /product="hypothetical protein"
                     /protein_id="WP_077060565.1"
                     /transl_table=11
                     /translation="MTGYKDVTDGNAVPHAIGLAVGKITQRGPWHDPDVVTQRLTMLGP
                     AVRATVVYGQARQAGMSISAATDKVVDDLVRYYAQRWYS"
     gene            893..1099
                     /locus_tag="STBA_RS19975"
                     /old_locus_tag="STBA_40470"
     CDS             893..1099
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_40470"
                     /product="hypothetical protein"
                     /protein_id="WP_077060566.1"
                     /transl_table=11
                     /translation="MANTTATTDESNNPIHLATDTVEGHVVTACGKWAAKTPVPRSTTF
                     RTAVTCVECAEWDQAWAYAVSSR"
     gene            1096..1353
                     /locus_tag="STBA_RS19980"
                     /old_locus_tag="STBA_40480"
     CDS             1096..1353
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_40480"
                     /product="hypothetical protein"
                     /protein_id="WP_077060567.1"
                     /transl_table=11
                     /translation="MSRDNASRLTAMKKRSKGAIRTVATSDAGRAACADDLALFDRVAN
                     NDGKVDPRDQGEAASICDGCPVNAGCGFRVAHPGPGRGER"
     gene            1620..2969
                     /locus_tag="STBA_RS19985"
                     /old_locus_tag="STBA_40500"
     CDS             1620..2969
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_40500"
                     /product="hypothetical protein"
                     /protein_id="WP_077060568.1"
                     /transl_table=11
                     /translation="MSDLTTLTNRLDPTAVTVAALVCGTLLTLALIWSVSLVVRQVTRR
                     RTRRAGQLDAMTPEQIDELRTREDRRRADMTTYAAAVIASGLSLVGMWPVVGVAVAESG
                     LPQVLHTPAAVALLGFLEAAVLASGRRARANVRVTGSTGVDGAALWIIVAFSAVVATTQ
                     AQSLTGALVKAGAPVVAAWMWERGLAPERRAYRGEKPAVHWRLGLRRVAVALRLADPEE
                     ADLAVLARARRLGQVASHIVRAKRRRRPARRWSLLRAERGLIRSAARGDFTREGGALTL
                     MDHIGLRAAAPHLVETNAPVPRDLFGLTGGPALAEVPSSTEPAVHAEPTATGDAPESPE
                     LPEKPAENDAENGENGENGLENPEESPENGGDTSENAEKPKLTIFRFTNGREAYTSAEL
                     DTARRLFAEYAERSGTRPPVNVVAKAINRRWERAKRVHDAVIAELSQSAT"
     gene            3058..3279
                     /locus_tag="STBA_RS19990"
                     /old_locus_tag="STBA_40510"
     CDS             3058..3279
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_40510"
                     /product="hypothetical protein"
                     /protein_id="WP_077060569.1"
                     /transl_table=11
                     /translation="MTVTFLPHQQAPASLPASPEPEHHSDPSLSPLPPEFGPIDVHSSM
                     PGWDEAAVRDELLRLLGIRIAPEPGGGW"
     misc_feature    complement(3406..3419)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.88"
                     /tool="antismash"
     gene            3720..4130
                     /locus_tag="STBA_RS19995"
     CDS             3720..4130
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_077060570.1"
                     /transl_table=11
                     /translation="MLSGTAPHRRWHGPTQDALFDWWGRRDRRQRFVLLNGTAAATGAY
                     SHGAFTGQWDVGLPQTVLAWMHDAAASSDEPATPLILGGLVALTAAVVGGIVSATLSRW
                     VAQLPRLCAALHWALVRVPVASAVTAILLYEA"
     gene            4142..4594
                     /locus_tag="STBA_RS20000"
                     /old_locus_tag="STBA_40530"
     CDS             4142..4594
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS20000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_40530"
                     /product="hypothetical protein"
                     /protein_id="WP_077060571.1"
                     /transl_table=11
                     /translation="MPHTVTPLAAEGDLTEAVGAISASGIALILVITLIYGVIGKGRRR
                     LASGPAQAIGIFAELAFLRANSFWRDIGEAIQSIPTGISTNAELGNPGMATVCAVLIVL
                     SLFARLVPASGALIGLLMGAAFEASDGSIWQAIVSIFSVPFGLLGA"
     gene            4651..5547
                     /locus_tag="STBA_RS20005"
                     /old_locus_tag="STBA_40540"
     CDS             4651..5547
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS20005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_40540"
                     /product="hypothetical protein"
                     /protein_id="WP_143659540.1"
                     /transl_table=11
                     /translation="MLVRSTRVMAVVVAAVARGEKVRAAVAERAPAMPSHRPTKAAAKN
                     AGTETKTPTKRGAGAGELTARLLLLVVLPGYVLIYLTGERPWLWYVYGGAWLFGCFMIA
                     AIRGDGPSEVPAEKSARRRPQAEKASTAPVKEGADTSEEHATENDHEMAESGEGYQEAE
                     HDAPAAGERERRIRIIQDRVEELVAAAVHEGKKGARTLDILAAFQARGGLHGWEEKPFR
                     ELLRSIGIPIRDQMYFKINGEKTNHPGVHVEDLTEHLGRAPLLPAHLVPDLTPVQAVEP
                     TSSPAPLPVQNAPPRGE"
     gene            5744..5980
                     /locus_tag="STBA_RS20010"
                     /old_locus_tag="STBA_40550"
     CDS             5744..5980
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS20010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_40550"
                     /product="hypothetical protein"
                     /protein_id="WP_077060573.1"
                     /transl_table=11
                     /translation="MAWRYECGDCDRRTTWMGRADVEDVRHQHHDTAHRGKAPAKERFT
                     SNAERVADNPRQLVFVLVIGILAAVVWVFDSIT"
     gene            6147..6620
                     /locus_tag="STBA_RS20015"
                     /old_locus_tag="STBA_40570"
     CDS             6147..6620
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014043713.1"
                     /locus_tag="STBA_RS20015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40570"
                     /product="hypothetical protein"
                     /protein_id="WP_077060574.1"
                     /transl_table=11
                     /translation="MAAASWSLGVVELNDGDRWATAVMQPDDEAQHGELAVRFKVAGLK
                     RSSAREWHAGLWPPTRCTITVVNGHLIQMHTGRSRVLCDPQPVSQGWQQAAARCRVVLA
                     LAPPGTWSPDMPTAELGTTADRGRLLDTAAEGRTLLVGLAEVRNTWEPYGRRW"
     gene            7086..8336
                     /gene="fxlM"
                     /locus_tag="STBA_RS20020"
                     /old_locus_tag="STBA_40580"
     CDS             7086..8336
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054574.1"
                     /locus_tag="STBA_RS20020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40580"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_077060575.1"
                     /sec_met_domain="PCMT (E-value: 1.1e-39, bitscore: 135.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPDSSSESAQAAALRGKMVDEVLEWRALLKLSLSSQVESVLRAV
                     PRHVFLPGLPLEEAYAQDAPVMKRDERDTIISSVSAPKIIAFMLDQLRVEPGHRVLEIG
                     SGGYNAALLKELVGPDGKVTTLDIDQDVVDRARKGLTAAGYDDVNVVCGDGEFGAEDFA
                     PFDRIIVTVQTWDVPPAWVEQLVEGGRLVAPFRIMRGQTRSVAFERDGDHLVSRGYELC
                     GCVPMQGAGENRELLIPLHGEEVGLRVDDGQQVNAELLRQAFAQPKVEAWSGVTVPRMT
                     PFDDLFLWLAFAAPNFCQLASSDAAIDKGLIPRSHRAPTIYNEESFGYLMLRRINPEDG
                     LSEFGVHAHGPSAEKIAEEYVTQIRAWDDRRSGPGPRFEVHPAGTPDDQLTQGRVVEKR
                     HTRVTISWPSVASTVEN"
     gene            8374..9594
                     /gene="fxlM"
                     /locus_tag="STBA_RS20025"
                     /old_locus_tag="STBA_40590"
     CDS             8374..9594
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="STBA_RS20025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40590"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_077060576.1"
                     /sec_met_domain="PCMT (E-value: 3.1e-40, bitscore: 136.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDNESRASALRERLIGELRQCEDIRTGRIATAFAAVPRHCFIPE
                     VPLEEAYVNDAVTTKRNERGKAISSVSAPWVQARMLELSGLGPGMRALEIGSGGCNAAL
                     IAEVVGEHGEVVSVDIDQEVTDRATKLLAETGYNERVRVLCGDGTYGAGEVAPEEGFDA
                     IIVTAQAPDLPPAWFDQLAERGRLVVPLSLRGTYYVWAFEHEGGHLRSRGRTSCGFVGM
                     QGDNRHGGRTIDLSGEDLRLGLDEDQQADAEALRSAVASSPQYTVWTEAILRGNEGVLP
                     SLDLWLIGTLDPSARSLYASTKAVHHGLSGWNVATIATWEGATLAYITIRPDPTSGGSE
                     LGVHAYGPDREVLAARLADRIRAWDAGGHRGSVEPTVRAYPISTPGDQIPRGQIVTRRY
                     SRFVISL"
     gene            complement(9634..9966)
                     /locus_tag="STBA_RS20030"
                     /old_locus_tag="STBA_40600"
     CDS             complement(9634..9966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124739.1"
                     /locus_tag="STBA_RS20030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40600"
                     /product="Lsr2 family protein"
                     /protein_id="WP_077060577.1"
                     /transl_table=11
                     /translation="MARKTVIIYTDDLTGKESDEARTHSFSVDGVQYEVDLAPESFDRL
                     LEVLGPFMENGRKLGRGRRAAGGARQVTPVEDSSKIREWAKEHGYQVSDRGRVPSDVRE
                     AYQKAH"
     gene            complement(10001..10831)
                     /locus_tag="STBA_RS20035"
                     /old_locus_tag="STBA_40610"
     CDS             complement(10001..10831)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="STBA_RS20035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40610"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_077060578.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.4e-34, bitscore:
                     118.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPNDQRNSWQQRILTFAEHHHVEPTAVARLGPGMKAAETPGPI
                     NSWFFIRKGKQLRLRYRPADSSSANEADLHVENLLAEMQRHAALKSWISTIYEPETYAF
                     GGPQGIATAHELFHQDSRNILDHLGRDTSDHDDKRRELSVLLCSALLRSAGLEWFERGD
                     VWDRVVGVRPHGDGSPPKPLPSITGALKKLMTVDTSSTSTLVNGGSLEFAGEWIAAFEY
                     AGKTLDKLSRSGVLTRGLRAVLAHHVIFHWNRIGLPSAVQGRMAATARQLIFRD"
     gene            complement(10856..12088)
                     /locus_tag="STBA_RS20040"
                     /old_locus_tag="STBA_40620"
     CDS             complement(10856..12088)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000961.1"
                     /locus_tag="STBA_RS20040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40620"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_077060579.1"
                     /sec_met_domain="LANC_like (E-value: 1e-43, bitscore:
                     148.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEWHQQRAQAAADTIADRLTTPPRRTPDPAEQGRPQSLSKGAAG
                     VALLHIERARAGLGRWDTAHAWLATAVRAPLNTGPNAGLLFGAPALAFAIHAAAESGRY
                     AKAHAALHASVEALARRRLAQAHARIDRGDQPAFREFDTFYGLTGIGVYLLRTDPHHDL
                     TREVLAYLVRLTEPLATDREDLPGWWTDLAPTGRPLPVFPGGHGNFGIAHGITGPLALL
                     SLALRSGLVVEDHAGAIGRICTWLDTWRQDHPFGPWWPETITRDEVRNQKPAQPGPWRP
                     SWCYGTPGLARAQQLAGIATGDLARQRMAEDALLGCLSDPDQLAHITDRSLCHGTAGLF
                     QTVWRAAADTTTPTLAAHLPRLLHLLLDHHQAPSESLGLLTGDAGLALALHTAATGTAP
                     ASGWDAFLLLT"
     misc_feature    complement(11492..11494)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12085..15177)
                     /locus_tag="STBA_RS20045"
                     /old_locus_tag="STBA_40630"
     CDS             complement(12085..15177)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="STBA_RS20045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40630"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_107485081.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.6e-200,
                     bitscore: 666.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2e-19,
                     bitscore: 68.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.3e-33, bitscore:
                     115.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLYEFVDAAHARAATHTRHLELPPWPDLNGNTSADAERWRCWLQ
                     RIWSLTPVAEAIEAASPVLTRRVSVLCEGALQQPRQVRRVVVSVVRYLLRMTSRATPFG
                     LFAGVTPVRFAASPRVRWGENHSAVARVDAVWLENTIRRLEQCSELLRRVPVMASNLCF
                     VRGSRLVLPFQQQASDASRRSTGEVSVRYTRAVAAAMREAGAPVLFGDLADKLAADFPR
                     ASPGVVDRMLAELVAQRILLTSLRAPMTVTDPLGHLVEQLTLADADSIGAVVMRELREV
                     RGELSQHNAAPADERRSLSASVVRRLTAGSSEVSRSLAVDLRLDCGLILPELVAREAER
                     AASALARLTPYPSGFPGWKDYHRRFLDRYGSGALVPVREIVNPDTGLGFPAGYRDTLNH
                     PPAQGLPDREVHLLALAQRAATEGGGEAVLDDEAISILAGPEIAHAQWTPHAELSFHVH
                     ARTAEALDRGEFRLVVASVSRAAGTMSGRFLDLFDDADRHRLVDMHASLPTVDGSALPA
                     QVSCPPLFIRTENVTRSTAVLPSVISLAEHQSGDGLVPLDDLAVGGDDQRLYLVSLSRR
                     RTIEPIVFSAVEFPRAAHPLLRFLCEIPKARVAALAPFSWGAASRLPFLPRVRYGRTVL
                     SPARWRLTSTDLPGRTATWAEWVDEFTASKQRLHFPGSVYLGEDDRRILLNLNESAHLF
                     LLRSHLDSKGHATLTEAPAPEAYGWFDGRAHEIVVPLAATAPRAWPPPRLTASITADRE
                     HGRLPGTSEWLFVKLYGHPDRQGDILTSHVPGLVSDCDEIRQWWYLRYHVPEHHIRLCF
                     RLPHPEAYGPALQRIGAWAADLRRLGLLRDMQVDTYRPETGRYGHGATMAAAEDVFAAD
                     SIAATAQLTHASATAGTHPYALTAASFVDMAVSFTGSVHSGTRWLLTNVANDPVPAPAR
                     HLHDTAVRLADPANEWASLRDAPGGDEITGAWTCRRRALATYRDRLSDTGDADPDTVLA
                     SLLHLHHLRMNGSDEDAERLCYRLARSASLSRTARTARRNQ"
     aSDomain        complement(14434..14712)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_STBA_RS20045_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="8.10E-22"
                     /identifier="RREFam001.1"
                     /label="STBA_RS20045"
                     /locus_tag="STBA_RS20045"
                     /protein_end="248"
                     /protein_start="155"
                     /score="68.7"
                     /tool="antismash"
                     /translation="VMASNLCFVRGSRLVLPFQQQASDASRRSTGEVSVRYTRAVAAAM
                     REAGAPVLFGDLADKLAADFPRASPGVVDRMLAELVAQRILLTSLRAP"
     gene            complement(15275..15427)
                     /locus_tag="STBA_RS36655"
                     /old_locus_tag="STBA_40640"
     CDS             complement(15275..15427)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS36655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_40640"
                     /product="FxLD family lantipeptide"
                     /protein_id="WP_107485082.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 5.1e-07, bitscore:
                     28.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDALITDDVEFDLDVSFIASEPDEEEKNPDTDDNCGGPQDSAGTT
                     CPSAG"
     gene            complement(15491..16717)
                     /gene="fxlM"
                     /locus_tag="STBA_RS20050"
                     /old_locus_tag="STBA_40650"
     CDS             complement(15491..16717)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000958.1"
                     /locus_tag="STBA_RS20050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40650"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_077060580.1"
                     /sec_met_domain="PCMT (E-value: 1.8e-36, bitscore: 124.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSDSASDAAALRNQMVDTILESRAALNRSLSGHVEAVMRKVPRH
                     AFLPGLALKDAYAQDAPVMKRDDDGVVISSVTAPKIMAGMLHQLDIEPGHRVLEIGSGG
                     YNAAMLRELVGPDGEVTTIDIDQDVINRARTCLATAGYADVRALCADGEVGAKEYAPFD
                     RIIVTVDSWDIPPAWVEQLAEDGRLVVPFRVLGLTRSIAFERTRDRLVSGSYELCGFVP
                     MQGAGARGLKVVRLQEKDVYLRVDRKHDFDAESLRAALKQPRVEAWSGVTARRGELMDE
                     QDLWLATVEDEFCILKATQEAIAQGLVHPSWRVATPALVQGGSFAYRAFPRAVDEKQTT
                     FEFGVYAHGPDAEEVANRFAEHLRVWDRDHRQGPGARFEVYPADTPDDHLTQGRVVNKR
                     HTRVTISWP"
     gene            complement(17287..17835)
                     /locus_tag="STBA_RS20055"
                     /old_locus_tag="STBA_40660"
     CDS             complement(17287..17835)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042672.2"
                     /locus_tag="STBA_RS20055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40660"
                     /product="DUF6624 domain-containing protein"
                     /protein_id="WP_077060581.1"
                     /transl_table=11
                     /translation="MAKPDEFGGSGLSSGSEIAAELVRRRNMDQEVRGLLPGTRPWPAE
                     LLERLRIIDAENTAFLKRVVAMHGWPGITLVGAEAAEAAWLLAQHADADGGFQCHAREL
                     LAEAVACGDASAWHLAYLTDRCLVAQERPQLYGTQYFDNGDGAGMRPRPIAEIDKLDAR
                     RVEVGLGPHADHDAHMRGR"
     tRNA            18322..18395
                     /anticodon=(pos:4421846..4421848,aa:Thr,seq:cgt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="STBA_RS20060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="STBA_40670"
                     /product="tRNA-Thr"
     gene            18322..18395
                     /locus_tag="STBA_RS20060"
                     /old_locus_tag="STBA_40670"
     gene            complement(18680..20647)
                     /locus_tag="STBA_RS20065"
                     /old_locus_tag="STBA_40680"
     CDS             complement(18680..20647)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012371.4"
                     /locus_tag="STBA_RS20065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40680"
                     /product="serine hydrolase"
                     /protein_id="WP_077060582.1"
                     /transl_table=11
                     /translation="MTARRVLAPVTLVLGFVLVLLSGLTPAFATSEHQASPQRVPNAPS
                     DPDDPDDPDELGARLDRLLRQQLDEYDIPGAAVSVVSADEQLMARGYGVPDSDHENQRV
                     EPERTGFFMGSVAKVFTAVAVLQLVEDGKLDLHTDVNRYLESFRIEDTYPDKPVTLHNL
                     LTHTAGFDFSIVGTASEDPRDAGDLGESLADNQPDRVREPGEAAAYDNYGVALAGYLVE
                     QITGQPFEEYVQREIIEPLGMSRTTFEQPHPKELEDALARGHRPSDGGQETTRGQYGAW
                     TPTGAAAVSTVTDMSRLMQALLGDSRLTDTRVLSDRSVQLLEQRHYGNDERLPGMAYIL
                     EERRHGEHRYLVKDGDMPGFHSNMVLFPDRDLGVYVNYNGDGDGGKAALAADEVAELAA
                     DFVYGGQAEGTSRPTVQEDVGQYEGSYRSNRTSHSDFTRASALTGSIEVSAGDDGILTT
                     NGPLSADPDVTEQRWRQIEPGVFQEIDGDARIAFEDGQLTVSSDVAVAFDRVPWYESPK
                     LHMRLLIGGLILISLTMICWPITALVRRSRDPRPGPRTARLLAWANSLLLGGVAVCFAL
                     LVADANVMNETVFLGDSPLLTAVPTLLAVSGAATAAMLCCAVLAYFRRWWGWVSRLHYA
                     LTGFAAVIVLMLAGNYALWG"
     misc_feature    20856..20871
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.39"
                     /tool="antismash"
     gene            20857..22188
                     /locus_tag="STBA_RS20070"
                     /old_locus_tag="STBA_40690"
     CDS             20857..22188
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718531.1"
                     /locus_tag="STBA_RS20070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40690"
                     /product="sensor domain-containing protein"
                     /protein_id="WP_079252043.1"
                     /transl_table=11
                     /translation="MSIVSDEKQRGPGGSRKDDLRPSSAFRAMGRSLALLALAPVEVLL
                     LTILVIVISLLSVGVGVFLVPAVVIAARGAMNIQRRCARDWSGVEIGDPYLSIRGTGPG
                     AKSWLQRTMGILSDPATWRDLLWMLVNPVVGVLILVLPLAVFAYGLFGVIMPFLWEPIV
                     DAGGNDWYLLVHVNNRGTALTAAVLGVPLMLMGYLMGPAMLRVHARFAHSLLGPTEMAR
                     KVHHLTATRSDAVNTSAAELRRIERDLHDGAQARLVAMGMNLGVAERLLGKDPEAARTI
                     LADTRTASAKALNELRDLVRGIHPPVLADRGLADAVRALGMDSPLRVAVNAELPSRPEA
                     PVESAMYFAISEALTNAAKHGSSRNVTVDVWYSEGTLRAQVTDDGTGGADPAKGTGLRG
                     LERRLATFDGVLALTSPVGGPTTLTMELPCVLSSPKTSSSSGTA"
     gene            22140..22808
                     /locus_tag="STBA_RS20075"
                     /old_locus_tag="STBA_40700"
     CDS             22140..22808
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180316.1"
                     /locus_tag="STBA_RS20075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40700"
                     /product="response regulator transcription factor"
                     /protein_id="WP_077060583.1"
                     /transl_table=11
                     /translation="MRAVLAEDQFLLRDGLIRMLRAYDFEIVAAVDNGPALLRALVDER
                     PDVAVVDVRLPPTFTDEGLQAALQARRELSGLPVLVLSQYVEQLYAKELLADGNGGIGY
                     LLKDRVFDPDEFIDAVHRVARGGTAMDPEVISRLFSGGSTAREGSITRLTARELEVLGV
                     MAEGRSNAAIAKRLVITERAVIKHTSNIFTKLDLPTSDDDNRRVRAVLTYLKDSGGTVE
                     "
     gene            complement(23212..24171)
                     /locus_tag="STBA_RS20080"
                     /old_locus_tag="STBA_40710"
     CDS             complement(23212..24171)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038083.1"
                     /locus_tag="STBA_RS20080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40710"
                     /product="CU044_5270 family protein"
                     /protein_id="WP_366510833.1"
                     /transl_table=11
                     /translation="MMNALPSLPERELPPGRHRQLKEHLMQEIQQDPVREETPSRRRWR
                     LRPAIAVPAAAGALAIAVTAGLMSWSSDDSERPVGRNGEATYSFAPNVNADTEGSAAEL
                     LTQVAAAAAGTPAAEDIREDQYVYIRSLVATAPVGDDIETELSEPIEREEWLTVGGADI
                     PAGEMGSERNTGYDHLQTLPTDPGAMLEWLRSHQDVESEGRNYDQDAFVLAGDLLRAPL
                     MPPDVGAALFGALARIPDVLVVPHAVDAAGRDAIAVVRYDSYNPGLREELMFDKDTLEL
                     IGSRSVATQATDTIEAGQVLHTMAVLERAVVDEDGERP"
     gene            complement(24168..24779)
                     /locus_tag="STBA_RS20085"
                     /old_locus_tag="STBA_40720"
     CDS             complement(24168..24779)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020684233.1"
                     /locus_tag="STBA_RS20085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_40720"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_077060585.1"
                     /transl_table=11
                     /translation="METTLRARIRDGDEDAFGRLFDAYARSVYNHAFRLTGDWSTAEDI
                     VSLTFLEAWRLRRRVDAEGGSLRPWLLGIATNTVRNTRRAARRHAAALTRLPPAEAVRD
                     FADEVAGRVDDAELLAVVRLALDSLRRNEREVLALCVWAELDYAAAAQALGIPVGTVRS
                     RLSRARKKLAAAARNLEPRHRSGQVRDSRAPAVRPAQEGK"
     misc_feature    complement(24816..24831)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
ORIGIN
        1 agacgcctct gccccccggc agccagccgg ggggcgccac actctctgag ctgcgcaact
       61 acgaccggca ggggccgggt gtgcgggtcc atggggcccg cggcgcccct cgcagcgccc
      121 ctgccggtca accatcccgc tcaactggcg ggcctccatt ctatgcgacg ctcatcagcg
      181 ccacccccaa ttaagaatgt tgacaaccgg ttatctgtac ccttaagctg ggcctgtcaa
      241 cacttcgaca ccggcgcacg agggggtatg tatgactggc tacaaggacg tcaccgacgg
      301 caatgccgta ccgcacgcga tcggcctggc cgtcgggaag atcacgcagc ggggcccgtg
      361 gcacgacccg gacgtcgtga cccaacggct aaccatgctc gggccggccg ttcgcgccac
      421 ggtggtatac ggccaggcgc gtcaagctgg gatgtccatc agcgcggcca cggacaaggt
      481 cgttgacgac ctcgttcggt actacgccca gcggtggtac agctgacgcc cgaggtaccc
      541 ctgcccctcc acggctctgc gtctccctgg caccgggcgg cgcagagccg agatcgcagc
      601 gatgccgcga tgcccgcagc agtcctggtg cgcgcgatgg gtctggaatg ctgactcttt
      661 cctggtgggc ccatggagcg gtctcgtcat ccagcgggct caggtgtggc acatttagaa
      721 tgttgacaac cggttatctg cacgcttaaa atggtatgaa cgcagcgcca ccagaccggg
      781 ttccatccct ctgtttcgtt agctgccaca cgcagcggcc cccaaccagc gaccctaacc
      841 gctggccagg ggcctgaaac ccgcctacct caacagcact gaggagcgag tcatggccaa
      901 cactacggcc accaccgacg agagcaacaa ccccatccac ctcgccaccg acacggtcga
      961 gggccacgtg gtcaccgcct gcggcaagtg ggccgcgaag acccccgtgc cccgatccac
     1021 gaccttccgc acggccgtca cctgcgtcga gtgcgcggag tgggaccagg cgtgggcgta
     1081 cgccgtgagc agccgatgag cagggacaac gcctcgcggc tcacggcgat gaagaagcgc
     1141 tccaagggag ccatccgcac ggtggccacc agcgatgccg gccgcgccgc ctgcgcggac
     1201 gacctcgccc tcttcgaccg agtcgcgaac aacgatggca aggtcgaccc ccgggaccag
     1261 ggagaggcgg cctccatctg cgacggctgc ccggtaaacg ccggctgcgg cttccgcgtc
     1321 gcacaccccg gccccgggcg gggtgagagg tgatgccgat cccgttccgg cgcacgccca
     1381 acggccgccg cgcccgcagg caggccgacg ccagcgcccg gcgcagttcc agggccaggc
     1441 gccacatccc cagcgactcc gagaccggcg gaggcgaagc cttcgccgac cgcaacgccc
     1501 gatccatcac ccggtggttt cgctcgtgac cgccgccgtc cgtgtccggt ccgccgtcgc
     1561 ttccgcgcgg cgggctgggc gctccaccct ccagaacact ctggccgagg aagccgtcca
     1621 tgtctgacct gaccacgttg accaaccggc tggaccccac cgccgtcacg gtggccgctt
     1681 tggtctgcgg cacgctgctg accctggcgc tgatctggtc cgtctcgctc gtggtgcggc
     1741 aggtcactcg acgccgcact cgccgcgcgg gacagctcga cgccatgacc cccgagcaga
     1801 tagacgagct gcggacccgg gaagaccggc gccgcgcgga catgacgacc tacgccgccg
     1861 ccgtcatcgc ctccgggctg tcgctggtgg gcatgtggcc cgttgtcggt gtcgcggttg
     1921 ccgagtccgg cctgccgcag gtactccaca ccccggccgc cgtcgcgctg ctcggattcc
     1981 tggaggccgc ggtgctggcc tccggccgcc gcgcccgagc caacgtccgt gtcaccggct
     2041 cgaccggcgt ggacggtgcc gcgctgtgga tcatcgtcgc cttctccgca gtcgtcgcaa
     2101 ccacccaggc ccagagcctg accggcgccc tggtcaaggc cggtgccccg gtcgtcgcgg
     2161 cctggatgtg ggagcgggga ctcgcccccg agcgccgcgc ctaccggggc gagaagcccg
     2221 ccgtccactg gcggctgggc ctgcgccgcg tcgccgtcgc gctgcgcctg gccgatccgg
     2281 aggaagctga cttggcagtg ctcgcccgcg cccgccgcct cggtcaggtc gcgagccaca
     2341 tcgtgcgcgc caagcgccgc cgccgaccgg cacgccgctg gtccctcctg cgtgccgaac
     2401 gcggcctcat ccgctccgcc gcacgcggcg acttcacccg cgaaggcggt gccctgacct
     2461 tgatggatca catcggcctg cgcgccgccg ctccccatct tgtggagacc aacgcccctg
     2521 tcccgcgcga cctgttcggc ctgaccggcg ggcccgccct agctgaggtg ccctcatcca
     2581 ccgaaccggc cgtgcacgcg gagccgacgg ccaccggcga cgcgccggag agcccggagc
     2641 tcccggagaa gccagcggag aacgacgcgg agaacgggga gaacggggag aacggcctgg
     2701 agaatccgga agagtccccg gagaacggcg gagacacctc ggagaacgcc gagaagccca
     2761 agctgacgat cttccggttc accaacgggc gcgaggccta cacctcggcc gaactggaca
     2821 ccgcccggcg gctcttcgcc gagtacgcgg agaggtccgg cacccggcct cccgtcaacg
     2881 tcgtggccaa ggccatcaac cgccgctggg agcgggccaa acgggttcac gacgccgtga
     2941 tcgccgagct ctcccagagc gccacatgaa tcgaaaattc gatcgaatgt ggagcggtcc
     3001 cggtagtagg ttggcagccg cgccgggacc gctccctccc aaaggagcag tctcatcatg
     3061 accgtcacgt tcctgcccca ccagcaggcc ccggcatcac tccccgcttc gcccgaaccg
     3121 gaacaccaca gcgacccgag cctctccccg ctgccgccgg agttcgggcc catcgacgtg
     3181 cactcgtcga tgcccggctg ggacgaggcc gccgtccgcg acgagctgct gcggctcctg
     3241 ggcatccgga tcgcccccga acccggaggc gggtggtgac catgaccgcc gatcagcaca
     3301 caccaccaca cagcccaaca tcgtcagaag agactccgac cacccctcag gctccacagc
     3361 cgcctcccca gccggactac gagccggaca tccacaagcg cacgcgcacg ctgcgtggcg
     3421 actggtggcg tatgcgcaat cccgtcccgg agaccgccgg ggaggcggcg gagccgacac
     3481 cgtacgcctc gccggctgcg ccggagaagt cgagcacccc cactccgccg gagtcggcgc
     3541 ccggctggtg gggggaggtg tacgacgacg ctctcggaga caccttcacc gctacgcccg
     3601 agcccccggc gacagaacaa cagacggatg aggcgccgcg gcaaccggac acgaccgaag
     3661 acccaccggc ggagaagaca ccgcccggag acggcgaaca caggccacgg ctgggtcgcg
     3721 tgctctccgg caccgcgccc catcggcgat ggcacggccc cacccaggac gccctgttcg
     3781 actggtgggg tcgccgcgac cgacgtcagc ggttcgtgct tctcaacgga acggccgccg
     3841 ccaccggcgc ctactcccac ggggccttca ccggacagtg ggacgtcggt ctgccgcaga
     3901 ccgttctggc ctggatgcac gacgccgccg cctccagcga cgagccggcc acacccctga
     3961 tcctcggcgg cttggtcgcc ctcaccgccg ccgtcgtcgg cgggatcgtc agcgccaccc
     4021 tcagccgctg ggttgctcaa ctgccgcggt tgtgcgccgc cttgcactgg gctctggtcc
     4081 gcgtccccgt cgcctctgcc gtcaccgcca tccttctcta cgaagcgtga ggaccaccgt
     4141 catgccgcac actgtcaccc ccctcgccgc cgaaggagac ctcaccgaag ctgtgggcgc
     4201 catctccgcc tccggcatcg ccctgatcct ggtcatcacc ctgatctacg gcgtcatcgg
     4261 aaaggggagg cgaaggctcg cctcgggccc ggcacaggcc atcgggatct tcgccgagct
     4321 cgcgttcctg cgcgccaact ccttctggcg ggacatcggc gaagccatcc agtcgatacc
     4381 caccggcatc tccaccaacg ccgaactcgg caaccccggt atggccaccg tctgcgccgt
     4441 actgatcgtc ctgtccctct tcgcacgtct ggtgcccgcc tccggtgccc tcatcggact
     4501 gctcatgggc gccgccttcg aagcatcgga cggaagcatc tggcaggcca tcgtcagcat
     4561 cttctccgtg cccttcggcc tcctcggagc ctgaccgtga gcctgtggga agagatcaac
     4621 atcttccgcg gggcgagcga agtcccgccc atgctggtgc gctccacccg cgtcatggcc
     4681 gtggtcgtcg cggccgtggc gcggggggag aaggtgcgcg ccgctgtggc ggaacgtgcc
     4741 cccgccatgc cttcccacag gcccacgaag gcggcggcga agaacgccgg cacagagacg
     4801 aagacgccca cgaagagggg agcgggagcc ggagaactca ccgcgagact gctgctcctg
     4861 gtggtgcttc ccggatacgt gctgatctac ctcaccggcg aacggccctg gctgtggtac
     4921 gtctacggcg gcgcctggct attcggctgc ttcatgatcg ccgccatacg cggtgacgga
     4981 ccctccgagg tgccggcgga gaagtccgcc aggcgtcggc cgcaggcgga gaaggcctcg
     5041 acggcgccgg tgaaggaggg ggcggacact tccgaagagc acgccaccga aaacgatcat
     5101 gaaatggcgg aatcggggga ggggtaccag gaagccgagc acgacgcccc ggcggccggt
     5161 gagcgagagc ggcgtatcag gatcatccag gaccgcgtcg aggagctcgt ggccgccgcc
     5221 gtgcacgagg gtaagaaggg cgcacgcaca ctggacatcc tggccgcatt ccaggctcga
     5281 ggcggcctcc acggttggga ggaaaagccg ttccgagagc tgctgcgcag catcggaatc
     5341 cccatccgcg accaaatgta tttcaagatc aacggagaaa agacaaacca ccccggcgtg
     5401 catgtagaag acctgaccga acacctcggt cgcgcaccac tcctgcccgc gcatctcgtg
     5461 cccgacctca cccccgtaca ggctgtagaa cccacctcct cgccggcccc cctcccggtc
     5521 cagaacgccc ccccgcgtgg ggagtgagag ggagcaacct aacggcgccg tcccgcggac
     5581 ctcgcatggg ccgctcccct cccccgtccc atccaccccc gtagccctac cttctacctc
     5641 tccactacca cgcttaccag gacaatccag gcgtcgtgtg tccggctgtc acccctcccc
     5701 gctaccgtca gaacacggcg gcacacacca ggaggagaag ccgatggcct ggcgctacga
     5761 gtgcggcgac tgcgacaggc gcaccacatg gatggggcgc gctgacgtgg aagacgtccg
     5821 ccaccagcac cacgacacag cccacagagg gaaagccccc gcgaaggagc gcttcacctc
     5881 caacgcggaa cgggtcgcgg acaaccctcg ccagctcgta ttcgtgctcg tgattggaat
     5941 cctggcagca gtggtctggg tgttcgactc catcacctga aacgacgagg agacatgcac
     6001 acctccgccg aacctccccg caccgcacgg acgacccgtg agtgcgagcc gcgcgcccgt
     6061 accctccgcc tgatccgccc cgaactctcc gatgccgccg acccgtctct ggcccacctg
     6121 aaggtcgccg aggaggtgac cggccagtgg ccgcagcctc ttggagcctg ggcgtcgtcg
     6181 agttgaacga cggcgaccgc tgggctaccg ctgtcatgca gcccgacgac gaagcccagc
     6241 acggcgaact cgctgtccgg ttcaaggtcg ccggactcaa gcgcagcagc gcccgagagt
     6301 ggcacgccgg tctgtggcct cccacccgat gcaccatcac cgtcgtgaat ggccacctga
     6361 tacagatgca caccggacgc tcccgggtgc tgtgcgaccc tcagccggtc tcccagggct
     6421 ggcagcaggc agccgcacgc tgccgcgtcg tcctcgccct ggcaccgccg ggcacctggt
     6481 cgcctgacat gccgacggcc gaactgggca ccacagcgga ccgaggccgt ctgctggaca
     6541 cggcggccga gggccggacg ctgctcgtcg gcctcgccga ggtccgcaac acatgggagc
     6601 cgtacgggag gcgatggtga cgtccgccgc tcccgacccg tcggccagat cagccaggca
     6661 cccgggcccc acctcgcggc gcctcggccg tcacgcctgt tctccgcgca ccggaaaacc
     6721 cggaggagcg ggggagactt cacgacggga ccagcgggac gtcacccggc cgcggacgtc
     6781 gattggcagc agacgagcaa cgtgctcgac gcgagttccc tctccgcgtt ccgcaaggat
     6841 ctgctcgccg cacgcccgct ccctgggttg gcccgagagc tcgcggagag gactcggctt
     6901 ccggagaact gtcggagaac cgcttcccgg agaccgccgg agagcttctc cgccccaccg
     6961 gtcaatcagc ggcgtggacc ttcccgactg ggcctctcgg aacaagccat gtggtagtcc
     7021 cacctcagcc ggacaactac acatccaccc tttgagggca cgctatgtga ctagactgcg
     7081 ggctcgtgat ccctgattcc agctccgagt ccgcccaagc tgctgcgctg cgcggcaaga
     7141 tggttgacga ggtccttgag tggcgtgccc tgctgaagct gtctctgtcg agccaggtcg
     7201 agtccgtgct ccgcgccgtg ccccgacatg tgttcctccc tggactgcct cttgaggagg
     7261 catacgcgca agatgcccca gtcatgaaac gggatgaacg tgacaccatc atcagctcgg
     7321 tctctgcgcc gaagatcatc gcgttcatgc tcgaccagct ccgtgtagag cctggccacc
     7381 gggtgctgga gatcggcagc ggaggttaca acgcggcact cctgaaggaa ttggtcggcc
     7441 cggacggcaa ggtcaccaca ctcgacatcg accaggacgt cgtcgaccgg gcccgcaagg
     7501 ggctcaccgc ggctggctac gacgacgtga acgtcgtctg cggcgatgga gagttcggtg
     7561 ccgaggactt cgcgccattc gaccggatca tcgtcaccgt ccaaacctgg gacgtccccc
     7621 cggcctgggt ggagcagctc gtcgaaggcg gccggctcgt cgctcccttc cggatcatgc
     7681 gaggacaaac ccgatctgtg gcgttcgagc gcgacggtga ccatctggtg agccgggggt
     7741 acgagctctg cggctgcgtg cccatgcagg gcgcagggga gaaccgggaa ctgctgatcc
     7801 ctctccacgg tgaggaggtc ggcctgcggg tggacgacgg tcagcaggtc aacgccgaat
     7861 tgctgcgcca ggcgttcgcc cagccgaagg tcgaggcgtg gtcgggagtg accgttcccc
     7921 gcatgacacc gttcgatgac ctcttcctgt ggctggcctt cgccgcgccg aacttctgcc
     7981 agctcgcgtc atcggacgcg gccatcgaca agggcctgat tccccgctcc caccgggctc
     8041 cgacgatcta caacgaggag agcttcggct acctcatgct gcggcgcatc aacccagagg
     8101 acggcctgtc ggagttcggc gtgcacgccc acggcccgag cgccgagaag atcgccgagg
     8161 agtacgtcac gcagatccgc gcctgggacg accgccgctc cggccctgga ccgcgcttcg
     8221 aggtccaccc ggccggcacg ccagatgacc agctcaccca aggacgtgtc gtggagaagc
     8281 ggcacacgcg ggtcaccatc tcctggcctt cggtcgcgag cacggtcgag aattaaggtc
     8341 gccaacactc caagggaaca gaagaccatc gtgatggagg acaatgaatc ccgtgcgtca
     8401 gcactgcgcg agagactgat cggcgagcta cgccagtgtg aggacatccg caccggccgg
     8461 attgcgacag ccttcgccgc ggtgccgcgg cactgcttca ttcccgaggt gccgttggag
     8521 gaggcgtacg tcaacgacgc ggtgacgact aagcggaatg agcgcggcaa ggccatcagc
     8581 tccgtctccg cgccctgggt gcaggccagg atgctggagc tgtctgggct ggggcctgga
     8641 atgcgggcgt tggagatcgg gtccggcggc tgcaatgccg ccctgatcgc cgaagtcgtc
     8701 ggtgaacacg gcgaggtcgt cagtgttgat atcgaccagg aggtcaccga ccgcgcgacg
     8761 aagctgctgg cagagaccgg ctacaacgag cgggtgcggg tgctgtgtgg ggacggcacc
     8821 tacggagctg gcgaggtcgc cccggaggaa ggcttcgatg cgatcatcgt caccgcccag
     8881 gcgcccgatc tgccccctgc atggtttgat caactcgccg agaggggacg gctggtggtc
     8941 ccgctcagct tgcgaggtac ctactacgtg tgggccttcg agcacgaggg tggacatctg
     9001 cgtagtcgtg ggcggacgtc gtgcggcttc gtcggtatgc agggagacaa ccgccacggc
     9061 gggcgcacta tcgatctgag cggtgaggac ttgcggctgg gccttgatga ggaccagcag
     9121 gccgacgccg aggcgctgcg ctccgctgtt gcctcctccc cgcagtacac cgtgtggacg
     9181 gaggcgatct tgcgtggcaa cgaaggcgtg ctgccctccc tcgacttgtg gctgatcggc
     9241 accctcgatc ccagcgcgcg gtcgctctac gccagcacca aggctgtgca ccacggcctg
     9301 tccggctgga acgtcgccac catcgcgacc tgggagggtg ccaccctggc gtacatcacc
     9361 atccgcccgg acccgacaag cggcggctcc gaactcggcg tgcacgccta cggccccgac
     9421 cgcgaagtgc tcgccgcacg gctcgcagac cgcattcgcg cctgggacgc cggagggcac
     9481 cggggttcgg tggagccgac cgtccgcgcc tacccgatca gcacccctgg cgatcagatc
     9541 ccacgaggtc agatcgtcac caggcgctac tcccggtttg tcatctcgct atagcgcgag
     9601 gctctgaggg aagagaccga cagtgcttcc aggttagtga gccttctggt acgcctcgcg
     9661 gacgtcggaa ggtactcggc cgcggtcgct cacctggtag ccgtgctctt tggcccactc
     9721 gcggatcttg gatgagtctt cgaccggcgt cacctgacga gcgccgccgg cagctcgccg
     9781 gccgcgtccc agcttccgtc cgttctccat gaaaggcccg agcacttcca agagccggtc
     9841 gaaggattcg ggtgccagat cgacctcgta ctgaaccccg tcaacggaga agctgtgtgt
     9901 gcgagcctcg tccgactcct tgccggtgag gtcgtccgtg tagatgatta cggtctttcg
     9961 tgccatgagg gaagggtaca gcagctcgga cgacctgaat tcagtctctg aagatgagct
    10021 gcctggctgt cgccgccatg cgcccctgca cggcggaggg cagacctatg cggttccagt
    10081 ggaagatcac gtgatgggct agcacggcgc gtagacctcg ggtgagaacg ccggaacgtg
    10141 agagtttgtc gagggttttt cccgcgtact cgaaggcggc tatccactcg ccggcgaatt
    10201 ccaatgaacc gccgttgacc aaagtgcttg tggagctggt atcgacggtc atgagcttct
    10261 tcaacgcgcc tgtgatcgaa ggcagcggct tcggtgggga gccatcacca tgggggcgga
    10321 cgccgaccac gcggtcccat acgtcgccgc gttcgaacca ctccagacct gcgctcctca
    10381 gcaaggcgct gcacaggagt acggacagct cacggcgctt gtcgtcgtga tcgctggtgt
    10441 ctcgtcccag gtggtcaagg atgttgcggc tgtcctgatg gaacagttca tgtgcggtgg
    10501 cgatgccttg agggccgccg aaggcgtacg tctcgggttc atagatggtg gagatccagc
    10561 ttttcagggc ggcgtgccgc tgcatttctg ccagcaggtt ctctacgtgg aggtccgcct
    10621 cgttggcgga ggagctgtct gcggggcggt aacggaggcg gagctgcttg cccttgcgga
    10681 tgaagaacca gctgttgata ggcccgggcg tctccgcggc cttcatcccc gggcccagac
    10741 gcgcgactgc tgtcggctcg acatggtggt gttcggcgaa ggtcagaatc cgttgctgcc
    10801 aggagttgcg ctggtcgttg ggctcgctca tgtcgggctc gtcccttcgg atgcgtcagg
    10861 tgaggaggag gaaggcgtcc cagccggagg ccggcgccgt gccggtggcg gcggtgtgga
    10921 gtgcgagggc caggccggcg tctccggtga gtaggcccaa gctctcgctc ggcgcctggt
    10981 ggtgatcgag gaggaggtgg agcaggcgcg ggaggtgggc ggcgagagtg ggggtggtcg
    11041 tgtccgcggc ggcgcgccag acggtctgga acaggccggc cgtgccgtgg cagaggctgc
    11101 ggtccgtgat gtgggcgagc tggtccgggt cggacaagca gccgaggaga gcatcttcgg
    11161 ccatccgctg acgggcgagg tccccggtgg cgatgcccgc gagttgctgt gcgcgagcga
    11221 ggccaggggt gccatagcac caggaaggcc gccaggggcc cggctgcgca ggcttctgat
    11281 tgcgcacctc gtctcgagtg attgtctccg gccaccacgg gccgaagggg tgatcttggc
    11341 gccaggtgtc cagccaggtg cagatgcgtc cgatggcgcc ggcgtggtcc tcaacgacga
    11401 ggccgcttcg cagggcgagg gacaggagcg ccagaggacc ggtgatgccg tgggcgatgc
    11461 cgaagttccc gtggccgccg gggaacacag gtaacggccg gccggtaggg gcgaggtcag
    11521 tccaccagcc gggcaggtct tcgcggtcgg tggcgagcgg ttcggtgagt cggacgaggt
    11581 acgccaagac ctcccgcgtg agatcgtggt gcgggtcggt gcgcaggaga tagacgccga
    11641 tgccggtcag cccgtagaag gtgtcgaact cccggaacgc gggctggtcg cctcggtcga
    11701 ttcgggcgtg ggcctgggcg aggcggcggc gcgcgagggc ttcgacgctg gcgtgcagtg
    11761 cggcgtgggc cttggcgtat ctgccggatt cggctgctgc gtggatcgcg aaggcgaggg
    11821 cgggggcgcc gaatagcagg ccggcgttgg gaccggtgtt gagcggggcg cgcacggcgg
    11881 ttgcaagcca ggcgtgtgcc gtgtcccacc tgccgaggcc ggcgcgggcg cgttcgatgt
    11941 gcagcagggc gactccggcg gcgcccttgg agagagactg cggacgccct tgttctgccg
    12001 ggtctggggt gcggcgcggt ggagtggtca gtcggtcggc gatggtgtca gctgcggcct
    12061 gggcgcgctg ttggtgccac tcggtcactg gttccgcctt gccgtgcggg cggtccggga
    12121 gagggacgcg gagcgggcca gtcggtagca gaggcgttcg gcgtcttcgt cgcttccgtt
    12181 catgcggagg tggtgaaggt ggagcaggga agcgagcacg gtgtcgggat cggcgtcgcc
    12241 ggtgtcggag agccggtcgc ggtaggtggc gagtgcccgt cgtcggcatg tccacgcccc
    12301 ggtgatctcg tcgccgcctg gggcgtctcg gagggatgcc cattcgttgg cggggtcggc
    12361 cagccgcacg gccgtgtcgt gaaggtgacg ggcgggcgcc gggacagggt cgttggcgac
    12421 gttggtgagc agccagcgcg ttccgctatg gacgcttccg gtgaagctga ccgccatgtc
    12481 gacgaagctg gctgcggtga gggcgtaggg gtgggtgccg gcggtggctg aggcgtgggt
    12541 gagctgggct gtggctgcga tcgagtcggc ggcgaacacg tcctcggcgg cggccatcgt
    12601 cgcgccatgt ccgtagcggc cggtttccgg acgataggtg tccacctgca tgtcacggag
    12661 cagcccgagc cgtcgcaggt cggctgccca ggcaccgatc cgctgaagtg ccgggccgta
    12721 cgcctcgggg tggggcaggc ggaagcacag tcttatgtgg tgttcaggga cgtggtaccg
    12781 caagtaccac cactggcgga tctcgtcgca gtcggaaacc aggccgggca cgtggctggt
    12841 gaggatgtcg ccctgccggt ccgggtgacc gtagagcttc acgaacagcc actccgaggt
    12901 tcccggcaga cgcccgtgct ctcggtcggc ggtgatggac gcggtcaggc gcgggggtgg
    12961 ccaggcccgg ggcgcggtgg ccgccagggg aacgacgatc tcgtgtgcgc gcccgtcgaa
    13021 ccacccgtac gcctccgggg cgggcgcctc ggtcaacgtg gcgtgcccct tgctgtccag
    13081 gtgggatcgc agcaggaaca ggtgggcgga ctcattcagg ttgaggagga tgcggcggtc
    13141 atcctcaccg aggtacacgc tgccggggaa gtggagccgc tgcttcgagg cggtgaactc
    13201 gtccacccac tccgcccacg tcgccgtccg ccctggtagg tcagtgctgg tcagccgcca
    13261 ccgcgcagga gagagcaccg tgcggccgta ccggacgcgc ggcaggaacg gaagccggct
    13321 tgcggctccc caggagaacg gcgccagggc agcgacccgt gccttgggga tttcgcacag
    13381 gaaccgaaga agcggatgcg cggcgcgtgg gaactccacg gcgctgaaga cgatgggctc
    13441 gatcgttcgc cgacgggaca gcgacaccaa gtagagccgt tggtcatcac cgcccaccgc
    13501 cagatcgtca agcggcacca gaccgtcgcc ggattggtgt tccgccagcg agatcacgga
    13561 cggaaggacc gccgtgctgc gcgtgacgtt ctccgtccgg atgaagaggg gtgggcacga
    13621 gacctgcgcc ggcagagcac ttccgtccac ggtggggagg ctggcgtgca tgtcgaccag
    13681 ccggtgccgg tcggcgtcgt cgaacaggtc gaggaaccga ccgctcatgg tgcccgccgc
    13741 ccgggacacg ctggcgacga cgagccggaa ctctccgcgg tccaacgcct ccgcggtccg
    13801 agcatggacg tggaaggaca actcggcatg gggtgtccac tgagcgtgcg cgatctccgg
    13861 gccggccagg atggatatcg cctcgtcatc gaggacggct tcgccgccgc cctccgtcgc
    13921 ggcccgctgc gccagcgcca ggaggtgaac ctcccgatcg ggcaagccct gggcgggcgg
    13981 gtggttgagc gtgtctcggt agccggcggg gaagcccagc ccggtgtccg ggttcacgat
    14041 ctcgcggacc ggcaccagcg caccgcttcc gtaccggtca aggaaacgac ggtggtagtc
    14101 cttccagccg gggaatcccg acggatacgg agtcaggcgg gccagggccg aagctgcccg
    14161 ctcggcttcg cgcgcgacga gctccggcag gatcagcccg cagtcgagtc gaagatccac
    14221 cgccaacgat cgggagacct cactagaacc cgcggtcaac ctccggacga cggaggcgct
    14281 gaggctgcgg cgctcgtcgg cgggcgcggc gttgtgctgg gacagctccc cgcggacctc
    14341 gcgcaactcg cgcattacca cggcaccgat cgagtcggcg tcggccaggg tgagctgttc
    14401 gacgaggtgg cccaacgggt cggtgacggt catgggagcg cgcaggctgg tgagcaggat
    14461 gcgctgggcc accagctcgg cgagcatccg gtccacgacc cccggcgagg cccgggggaa
    14521 gtcggcggcc agcttgtctg ccagatcgcc gaacaggacc ggcgcccccg cttcccgcat
    14581 ggccgctgcc accgccctgg tgtagcgcac cgacacttcg ccagtcgacc gtcgggaggc
    14641 atcagaggcc tgttgctgga aggggagcac caatcggctg ccccgcacga agcacaggtt
    14701 gctcgccatg accgggacac ggcgtagcag ctcagagcac tgttccaagc gcctgatcgt
    14761 gttctccagc cagacggcat ccacgcgcgc cacggcgctg tgattctctc cccatcgcac
    14821 ccgtggagac gcagcgaacc ggaccggggt cactccggcg aacagtccga agggcgtcgc
    14881 ccggctcgtc atccgcagca gatagcggac cacggagacc acgacgcggc gcacctggcg
    14941 tggctgctga agggccccct cgcacagaac actcacgcga cgagtcagga ccgggctcgc
    15001 tgcctcgatg gcttccgcga ctggggtcag cgaccatatt cgctggagcc agcaacgcca
    15061 ccgttccgcg tccgcgctgg tgttgccgtt caggtctggc cagggtggca gttcgaggtg
    15121 gcgtgtgtgg gtggcggccc gagcgtgggc cgcatcaaca aattcgtaca accgcaacgc
    15181 tctcccaggg ttcgcacgta acggaggacc cgacgccgaa accgggggag aggggtattt
    15241 cgacgccggg tctggttaac cgattgtcgt cgtcttagcc ggcgctcggg caggtggtac
    15301 cggcgctgtc ttggggcccg ccgcagttgt catctgtgtc gggattcttt tcttcttcat
    15361 ccggctcgga tgcgatgaag ctgacatcaa ggtcgaattc cacgtcatcc gttatcagag
    15421 cgtccattca tttcctcctg tgggaaggga tatggtggaa cctgtcctga gggtggggtg
    15481 ttgttgtccg tcagggccag gagattgtga cccgcgtgtg tcgtttattg acgacacgtc
    15541 cctgggtgag gtggtcatct ggcgtgtcag ccggatagac ctcgaagcgt gctccaggcc
    15601 cctggcggtg atcacggtcc cagacgcgga gatgttcggc gaatcggttc gcgacctctt
    15661 cggcatccgg gccgtgggca tatacgccga actcgaacgt ggtttgcttc tcatcaaccg
    15721 ctcggggaaa ggcgcgatag gcgaagctgc cgccctgaac caatgccgga gtagcgacgc
    15781 gccaggacgg atgaaccagc ccctgcgcga tcgcttcctg tgtcgcctta aggatgcaga
    15841 actcgtcctc gacggtagcc aaccataggt cctgttcatc catgagttcg cctcggcggg
    15901 ccgtcacccc ggaccaggct tccaccctcg gctgcttgag cgcggcacga aggctctcgg
    15961 cgtcaaaatc gtgcttccgg tccacccgaa ggtacacgtc tttctcctga aggcggacaa
    16021 ccttcagtcc gcgtgccccg gcaccctgca tcggcacgaa gccgcacagt tcgtagcttc
    16081 cgctcaccag acgatcacgt gtgcgttcga acgcgatcga tcgggtcagg ccgagaaccc
    16141 ggaacgggac gaccaggcgt ccatcctcgg cgagctgctc cacccaggcc ggggggatgt
    16201 cccaggaatc cacggtgacg atgatccggt cgaacggcgc gtactccttg gccccgacct
    16261 caccgtcggc acacagtgcc cgcacgtccg cgtagccagc cgtcgccaga catgtacggg
    16321 cccgattgat cacatcctgg tcgatgtcga tcgtggtgac ctcaccgtcc ggaccgacca
    16381 gctcacgcag catcgccgcg ttgtaccccc cgctgccaat ctccagcacg cggtggccag
    16441 gctcgatgtc cagctggtga agcatcccgg ccatgatctt gggggcggtg actgagctga
    16501 tgacgacacc gtcgtcatcc cgtttcatga ccggcgcgtc ctgcgcgtat gcatccttca
    16561 gtgccaaccc ggggaggaac gcgtgccggg gaaccttccg catcaccgcc tcgacgtgac
    16621 ccgacagcga ccggttaagc gcggcacgcg attccaggat cgtgtcaacc atctggttcc
    16681 gcagtgcggc ggcatcggag gcggagtctg aagtcatggg atgaagtgta gtcacgcagt
    16741 gtcctctccc cgagtgaaaa cagtaatgag gcacgggagg ttggctgcgc cggcatggtt
    16801 gcgtcgcgcg gactcaaagc tctgcttgca tggcttcccc ggcgacgagc ggcctgctgg
    16861 ccgcagtctt gaacagccgt ccaaagccgt tgacggcccg tccacatgcc tggcggcttt
    16921 gcgccgtccg cgccgtcgcg ctcggccagc tgcgtagcag gtcacgacac ctacgctcgg
    16981 gtgtttcgtc cgtgataccg cgcggataat cagttgaggt taaaagtact gcttagtagc
    17041 ctcctgctcg ggtctatgcc ttgcgcatat ggcctggtcg ggagcgcgta tcggcagccg
    17101 ccctccgagc ccccggcgcc tggcccctcg cctccatgaa ggtggggggt cacttcttga
    17161 atgggggcac cacggctgtg cccggacggg atggggtcgt ttcgccgcca gctgaggaaa
    17221 agctcagaag tcgccctttg tgcctgaagc gttggcggcg gcctcggcga gggccagggc
    17281 ggcgcctcag cgaccgcgca tgtgtgcgtc gtggtcggcg tggggtccca ggccgacctc
    17341 aacgcggcgt gcgtccagct tgtcgatctc ggcgatgggg cgcggacgca tccctgcgcc
    17401 gtccccgttg tcgaagtact gagttccata cagctgagga cgttcttgtg ccacgaggca
    17461 tcgatccgtg aggtaggcca ggtgccaggc agaggcgtca ccgcatgcca cggcctcggc
    17521 gaggagttct cgcgcgtggc attggaagcc tccatcggca tcagcgtgct gggccaggag
    17581 ccaggccgcc tcggccgcct ccgcgcccac cagggtgatg ccgggccatc cgtgcatggc
    17641 gacgacgcgt ttgaggaagg cggtgttctc ggcgtcgatg atgcgcagac gctcaagcaa
    17701 ctcggcaggc catggccgcg tccccgggag caacccgcgc acctcctggt ccatgttcct
    17761 gcgacgcacc agttccgcag cgatctccga acccgagctg agcccggagc ccccgaactc
    17821 gtcaggcttc gccatcacgt ctccccatcg tctatgccaa cgtcctgacc agaccctgcc
    17881 cgctcagctc agccgttcct cttcccgcgg ctgccacgcc ggcgtcagac ggggagcccg
    17941 aagacggggg agctgtgact tcctcggcaa caccgtgggc gttcccctcc gtcaggacgc
    18001 caaggcttcg ccgacatgcc cgcctggtcg ggcggctgga cgacgcgtcg gccgcggttg
    18061 atcgccgggc actccctgtc tggcctgtgc tgcccacgga cgtccatcgt ggtggcgcgc
    18121 caaacactct ttgctttacg ccagcaaact aagcaggtca gagctggtct gcgcgtgagt
    18181 gtggcgtgag cgtggcgtga gcggacgccc ttggatgaac ctctccgagg ctcgctctgc
    18241 tggatgaacc gaactgccta cggggcgcgc ccgcggctgt ataccctggt cagggcgcat
    18301 ttccgctggc aggcgggcca agccgcctta gctcagtcgg ccagagcgac gcactcgtaa
    18361 tgcgtaggtc aagggttcga ttcccttagg cggctccggc agcccaggtc agatagcgtc
    18421 tgacctgggt tttctactgc tcggggcatg acgcgtcata cggccggggt gccgtgcagt
    18481 ggtttgtgtg agcggagggg ccgcgagttc tgcttcttgg gcttcttcgg cctgtccttc
    18541 ttcttgtcct cggcctgcct cgaagagatc gctcaccttg ccggggtgcg ggcaggagcc
    18601 gtcctcctga gtggagaccg cccgctcggc ctcctgccgc tcgcggtggt cccgcgacga
    18661 gctggccggg gccgcggagt cagccccaca gcgcgtagtt cccggccagc atcagcacga
    18721 tcaccgccgc gaatccggtc agggcgtagt gcagtcgcga gacccagccc caccagcggc
    18781 ggaagtaggc cagcaccgcg cagcagagca tcgccgcggt ggccgccccg gagacggcga
    18841 gtagcgtcgg tacggcggtc agcagcggtg agtcgcccag gaacactgtc tcgttcatta
    18901 cgttggcgtc cgcgaccagc agcgcgaagc agaccgccac cccgcccagc agcaggctgt
    18961 tggcccaggc cagcagccgg gccgtgcgcg gcccggggcg cgggtcacgg gagcggcgca
    19021 cgagcgcggt gatcggccag cagatcatgg tgagcgagat caggatgagc ccgccgatga
    19081 gcaaccgcat gtgcagcttc ggcgattcgt accaggggac cctgtcgaag gcgaccgcga
    19141 catcgctgct cactgtgagc tgaccgtcct cgaaggcgat cctggcgtcg ccgtcgatct
    19201 cctggaacac gcctggttcg atctgccgcc acctctgctc ggtgacgtcc gggtcggcgc
    19261 tgagcgggcc gttggtggtc aggatgccgt cgtcgccggc cgagacctcg atcgagccgg
    19321 tcagcgcgga ggcgcgggtg aagtcggagt ggctggtgcg gttggagcgg taactgccct
    19381 cgtactggcc gacgtcctcc tgaacggtcg gccgggacgt gccttccgcc tgcccgccgt
    19441 agacgaaatc ggcggccagc tccgcgactt cgtcggcggc cagggcggcc ttgccgccgt
    19501 cgccgtcgcc gttgtaattg acgtacacgc cgaggtccct gtccgggaac agcaccatgt
    19561 tggagtggaa gcccggcatg tcgccgtcct tgaccaggta gcggtgctcg ccgtgccgac
    19621 gctcctccag gatgtaggcc atgcccggca gccgctcgtc gttgccgtag tgccgctgct
    19681 ccaggagctg tactgacctg tcactgagca cccgcgtgtc cgtcagccgg ctgtcgccca
    19741 gcagggcttg catcagccgg ctcatgtcgg tgacggtgga gacggcggcg gcccccgtcg
    19801 gggtccacgc tccgtactgc cctctcgtgg tctcctgccc gccgtcggac ggccggtgcc
    19861 cgcgggcgag cgcgtcctcc agctccttcg ggtgcggctg ctcgaaggtc gtacgggaca
    19921 tgccgagcgg ttcgatgatc tcccgctgga cgtactcctc gaagggctgc ccggtgatct
    19981 gctcgaccag gtaaccggca agcgccacac cgtagttgtc gtaggccgcg gcctcgccgg
    20041 gctcgcgcac ccggtccggc tggttgtccg ccaggctctc gcccaggtcc ccggcgtcgc
    20101 gcgggtcctc actggccgtg ccgacgatgc tgaagtcgaa accggcggtg tgggtcagca
    20161 ggttgtggag tgtgaccggt ttgtctggat aagtgtcctc gatccggaag ctctccaggt
    20221 acctgttcac gtcggtatgc aggtccagct tcccgtcctc gacgagttgc agcaccgcga
    20281 ccgcggtgaa gaccttggcg accgagccca tgaagaaccc cgtacgctcc ggttccaccc
    20341 gctggttctc gtgatccgag tccggcacgc cgtaaccgcg cgccatcagc tgctcgtcag
    20401 cggataccac ggaaacggcg gcgcccggga tgtcgtactc gtccaactgc tgcctcagca
    20461 gcctgtccag acgcgcgccc aactcgtccg gatcatccgg atcgtccgga tcggacgggg
    20521 cgttcggcac ccgctgcggc gacgcctggt gttccgacgt cgcgaaggcc ggggtgagtc
    20581 cgctcagcag caccaggacg aatccgagta ccagggtcac gggggcaagg actcgtcggg
    20641 ctgtcatctg ttggctcctt cggccgcact cggaaagttc cgatgacggc aagccaactg
    20701 ttcgcggacc gtacgtgcca tggccctttg tagtctcggc agggtactta actacaccct
    20761 gggagacgcc actgaggtcc aatgaggaat cccgcccccg tccgcagact gggatctgca
    20821 cagcggtaac cggccgccag tcgaggggaa cacggaatga gcatcgtcag cgacgagaag
    20881 cagcgcggcc cggggggcag ccgcaaggac gacctgcggc cctccagtgc cttccgtgcg
    20941 atgggccgtt cgctggcgct cctcgcgctc gcgccggtgg aggtactgct cctcaccatc
    21001 ctggtgatcg tgatctccct cctgagcgtg ggtgtcggtg tcttcctcgt accggcggtc
    21061 gtgatcgccg cacgcggggc gatgaacatc cagcgtcgct gcgcccggga ctggtcgggc
    21121 gtcgagatcg gtgacccgta cctctccatc cggggcaccg ggcccggcgc gaagagctgg
    21181 ctccagcgca ccatgggcat cctcagcgac ccggccacct ggcgcgacct gctgtggatg
    21241 ctggtgaacc cggtggtggg cgtgctgatc ctggtgctgc cgctggccgt cttcgcctac
    21301 ggcctcttcg gcgtcatcat gcccttcctc tgggaaccga tcgtggacgc gggcggcaac
    21361 gactggtacc tgctggtgca cgtcaacaac cgcggcaccg cgctgaccgc cgccgtgctg
    21421 ggcgtccccc tcatgctcat gggttacctg atgggcccgg ccatgctgcg ggtgcacgca
    21481 cggttcgcgc acagcctgct cggccccacc gagatggcgc gcaaggtgca ccacctcacc
    21541 gccacccgca gcgacgccgt gaacaccagc gccgccgagc tgcgccggat cgagcgggac
    21601 ctgcacgacg gcgcgcaggc ccggctggtc gcgatgggca tgaacctggg cgtcgccgag
    21661 cggctgctcg gcaaggaccc ggaggccgcc cgtacgatcc tggccgacac ccgcaccgcc
    21721 tccgcgaagg cactgaacga gctgcgcgac ctggtccggg gcatccaccc gccggtgctg
    21781 gccgaccgcg gcctggccga cgccgtacgc gccctcggga tggacagccc gctccgggta
    21841 gcggtgaatg cagagctgcc gagccggccg gaggcgcccg tggagtccgc gatgtacttc
    21901 gccatctccg aggcgctgac caacgcggcc aagcacggtt cctcccggaa cgtcacggtg
    21961 gacgtctggt actccgaggg cacgctgcgt gcccaggtga cggacgacgg caccggtggc
    22021 gcggaccccg cgaagggcac cgggctgcgc ggtttggagc ggcggcttgc taccttcgat
    22081 ggcgttctgg ccctcaccag cccggttggc ggcccgacaa cactcaccat ggagctgcct
    22141 tgcgtgctgt cctcgccgaa gaccagttcc tcctcaggga cggcctgatc cggatgctcc
    22201 gggcgtacga cttcgagatc gtcgcggcgg tggacaacgg tccggctctg ctccgagccc
    22261 tcgtcgacga gcgccccgac gtggccgtgg tggacgtacg ccttcccccg acgttcaccg
    22321 acgagggcct tcaggccgcg ttgcaggccc gccgtgagct gtccggactg ccggtgctgg
    22381 tgctgtcgca gtacgtggag cagctgtacg ccaaggagct gctggccgat gggaacggcg
    22441 gcatcggcta cctgctcaag gaccgggtgt tcgacccgga cgagttcata gacgccgtgc
    22501 accgcgtcgc gcgcggcggc accgcgatgg acccggaggt catctcgcgg ctgttcagcg
    22561 gcggcagtac ggcgcgggag ggctccatca cccggctgac cgcccgggag ctggaggtgc
    22621 tcggggtgat ggccgagggc cgctccaacg ccgcgatcgc gaagcggctg gtgatcaccg
    22681 aacgggcggt catcaagcac acctcgaaca tcttcaccaa gctcgacctg cccacctcgg
    22741 acgacgacaa ccgccgggtg cgcgccgtgc tgacgtacct caaggactcg gggggcacgg
    22801 tcgagtaggc gcgagggcct ctcgacagca cactgcccgt cgggtaccgg cagtgcgaac
    22861 ttccgtacac cggggagagt ccggtcctgc cgcatcagat cggccgcgat ggcgcgtacg
    22921 gagccacggc gtacgcccgg gggaatcaca tcgggaagga cccgcttcgt ctcgtccttg
    22981 ccgagaaggc gcccgagcat gcgggcgcgt ccagcgtgtg cgccgccctc gccgatccgg
    23041 atggcgtgcc ggtgcctcgc accggcacgc catctcttct gccgcggcaa gttggacctt
    23101 gcagtcggcg aagggacact ggtcccgttc ggccggagtg cgtcttcccg gccgctggtt
    23161 gcggtcgtgg cccgagcggt gtccccgccg cgccggcgga gccgccaagt gctacggacg
    23221 ttcgccgtcc tcgtccacca cggcgcgttc cagaacggcc atggtgtgca ggacctggcc
    23281 ggcctcgatg gtgtcggtgg cctgggtcgc gacgctgcgg gagccgatga gctccagcgt
    23341 gtccttgtcg aacatcagct cctcgcgcag cccagggttg taggagtcgt agcggacgac
    23401 ggcgatggcg tcccggccgg ccgcgtccac tgcgtgggga accaccagca catccggaat
    23461 ccgcgcgagg gcgccgaaaa gcgcggcgcc gacgtcgggc ggcatcagcg gtgcgcggag
    23521 gaggtcaccg gcgagcacga aggcgtcctg gtcgtagttc cgtccctcgg actccacatc
    23581 ctggtgggag cgcagccact ccagcatcgc gccggggtcc gtgggcagcg tctggagatg
    23641 gtcgtagccg gtgttccgct cggaccccat ttcgccggcg gggatgtccg cgccgccgac
    23701 ggtcagccac tcctcgcgtt cgatcggctc cgagagctcg gtttcgatgt cgtcgcccac
    23761 cggcgcggtg gccaccaggc tgcggatgta cacgtactgg tcctcgcgga tgtcctcggc
    23821 agccggggtc ccggccgccg ccgccgccac ctgggtcagc agctcggcgg cgctgccctc
    23881 ggtgtccgcg ttcacgttgg gggcgaaaga gtacgtcgcc tcgccgttcc tgccgaccgg
    23941 ccgttcggaa tcgtccgaac tccacgacat gagccccgcg gtcacggcga tcgccagcgc
    24001 gcccgcggcg gccgggacgg cgatcgccgg gcgcagccgc caccggcggc gggacggagt
    24061 ttcctcccgc acggggtcct gctggatttc ctgcatcagg tgctccttga gctgtcggtg
    24121 acggcccggc gggagctccc tctcggggag agacggaagt gcgttcatca ttttccctcc
    24181 tgggcgggcc tgaccgctgg tgcgcggcta tctctcacct gtcctgagcg gtggcgcggt
    24241 tccagatttc gtgccgcggc cgcgagcttc ttccgggcgc gggacagccg ggaacggacg
    24301 gtgccgacgg ggatgccgag cgcctgggcg gctgccgcgt agtccagttc cgcccacacg
    24361 cacagcgcga ggacttcccg ttcgttgcgc cgcagactgt cgagggcgag ccggacgacg
    24421 gccagcagtt ccgcgtcgtc gacccggccc gccacctcgt ccgcgaagtc ccgcacggcc
    24481 tcggcgggcg gcagccgggt cagcgccgcg gcgtgacgcc gggcggcgcg gcgggtgttg
    24541 cggacggtgt tcgtggcgat cccgagcagc cagggacgca gcgatccgcc ctcggcgtcg
    24601 acgcgcctgc gcagccgcca ggcttcgagg aacgtcagcg agacgatgtc ctcggcggtc
    24661 gaccagtccc ccgtcaggcg gaacgcgtgg ttgtaaacgg agcgtgcata cgcgtcgaac
    24721 agccgcccga aggcgtcctc gtcgccgtcg cgtatgcgcg cccgtagtgt cgtctccata
    24781 ctccgagccc tgtccgggcc acgggggccg gttcccgtga gtcaagtcac aggctgcgtt
    24841 ccttcgcggt gagcgcgcgt cactgctcgg gcagtatccc gcccttgagc gatatcgcaa
    24901 tcatccgaaa gcggaatggt tcggcgagcg gctgcttctt gcggagggcg gcgacggtga
    24961 cccgcggacg gccatggcgt tccgccgagc tgggagccgc gtccggcatt ctgatgcttc
    25021 gcagcccgaa gagaagccag tgccgtggtc gcgcggaccg tccaccccgc cgtcggcccc
    25081 cgccgctggc aacccaagaa gctgaccgct tttgagagga aggccggttg gcgctatcgc
    25141 gtcaccgcga ccgacatcca ccgcatgcgg ggcagta
//
