LOCUS       NZ_LZNS01000001        22549 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4353726
            Orig. end                         :: 4376275
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22549
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="23"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22549
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22549
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12549](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12549)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    284..299
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 24.66"
                     /tool="antismash"
     gene            complement(1187..2005)
                     /locus_tag="STBA_RS19650"
                     /old_locus_tag="STBA_39790"
     CDS             complement(1187..2005)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174684.1"
                     /locus_tag="STBA_RS19650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39790"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_077063441.1"
                     /transl_table=11
                     /translation="MPLDLRLDIPHSARMYDFYLGGKDNYAPDREAARQVEAVFPGISV
                     CARENRHFMHRVTRMLVAQHGMRQWLDIGTGIPTSPNLHEVAQDVEPQVRVVYVDNDPI
                     VLAHARALLNSSPEGRTAYIQADVRHPERILAAPQLTATLDLCQPIVLSLHAVLHFVPD
                     ESDPYGIVRRLLDALPSGSALALSHCTPDFDPETWARVVDIYRAGGTPAQVRSRSEVER
                     FFEGLDLAEPGLEVAHRWRPDPEEVPRRHFPGPEVNDATVSLWAGVGFKP"
     gene            complement(2197..2619)
                     /locus_tag="STBA_RS19655"
                     /old_locus_tag="STBA_39800"
     CDS             complement(2197..2619)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_39800"
                     /product="hypothetical protein"
                     /protein_id="WP_077060505.1"
                     /transl_table=11
                     /translation="MTAIDWLVPPDYIALPSVLDGRQPEVVHLGESEGMVALCWLRGRG
                     GTVGPVRLCRRHRTLAVPVEEPVPVGRWRSRPVLECGGGRRCDAQMWLLPGPARECPGL
                     TEPYGLTEALFATGSERQAEARFFRGIVPAGFGPRL"
     misc_feature    complement(2814..2828)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     misc_feature    2815..2829
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 23.58"
                     /tool="antismash"
     misc_feature    complement(3594..3614)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.0"
                     /tool="antismash"
     misc_feature    complement(3812..3827)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.6"
                     /tool="antismash"
     gene            3892..5271
                     /locus_tag="STBA_RS19660"
                     /old_locus_tag="STBA_39820"
     CDS             3892..5271
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_39820"
                     /product="transcriptional regulator"
                     /protein_id="WP_077060506.1"
                     /transl_table=11
                     /translation="MSRLAQVTSGIYVHPLSYVRAERGWTQQDVVDVIAERVGGSARRN
                     KAWLWENRNVVPDWPSQVALAAELGIPESRLVEEPWPQWLPDGDPIRTDFAWSQTGSIQ
                     ALEDVLEHGVRDRRGFMKLTGSALVALAHDWLRAEPAELVAALRGGRVADTFVDRLEEG
                     LPRLRFLEAERGGQEARRLIDAELGLVAEVLANSSYTIETGRRLYALAGELGRMAGWAS
                     FDAGLHAAAQRYWAAAIHAAHAADDRPLGANIMKSMSLQCYDFADPAEALALARSAYEG
                     ASDTTPRTVAMFALREARAHAALGDLSACERLLGEAESAVSRADTAVDPDPAWIGYFDD
                     AEFYAQIGTCYLDLGTRHGDRRQFTRADTYLAKTLRLLPETKVRDRATYLTRRASAQTQ
                     LGNLDRACQLLTDTIPLVHSAPSQRNIRRMFTVRNRLPLNRRDARARALDEHLRVLTNA
                     S"
     gene            5268..5975
                     /locus_tag="STBA_RS19665"
                     /old_locus_tag="STBA_39830"
     CDS             5268..5975
                     /NRPS_PKS="Domain: PKS_KR (6-131). E-value: 7.4e-12. Score:
                     37.5. Matches aSDomain:
                     nrpspksdomains_STBA_RS19665_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010262816.1"
                     /locus_tag="STBA_RS19665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39830"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_077060507.1"
                     /transl_table=11
                     /translation="MTELQRVALVTGANRGIGLAIARGLAQRGLHVVLGARTEAAAETE
                     AAALTADGLAASAHQLDVTDPVSVARAAADTANQLGRLDVLVCNAGVAIDRGQPASSPD
                     FEKVRATLEVNLLGAWRCCAAAIPEMRKHDYGRIVTITSHLGSITTMADTNVGYRVSKA
                     GLNALTRILAAELDGSGILVNAASPGRTDTRMAYRETDRTPEEAADTPIWLATLPDDGP
                     SGGLFYERKPLAW"
     aSDomain        5286..5660
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STBA_RS19665_PKS_KR.1"
                     /evalue="7.40E-12"
                     /label="STBA_RS19665_PKS_KR.1"
                     /locus_tag="STBA_RS19665"
                     /protein_end="131"
                     /protein_start="6"
                     /score="37.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VALVTGANRGIGLAIARGLAQRGLHVVLGARTEAAAETEAAALTA
                     DGLAASAHQLDVTDPVSVARAAADTANQLGRLDVLVCNAGVAIDRGQPASSPDFEKVRA
                     TLEVNLLGAWRCCAAAIPEMR"
     CDS_motif       5292..5354
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS19665_0001"
                     /evalue="2.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="STBA_RS19665"
                     /protein_end="29"
                     /protein_start="8"
                     /score="16.9"
                     /tool="antismash"
                     /translation="LVTGANRGIGLAIARGLAQRG"
     gene            6138..>6308
                     /locus_tag="STBA_RS39525"
                     /pseudo=""
     CDS             6138..>6308
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="STBA_RS39525"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAETFGQALRRLRGDLSQRRLGERVFCHKSHIYRLEVGLRGPSPD
                     MAERLDRELAAG"
     misc_feature    6143..6157
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            6516..7568
                     /locus_tag="STBA_RS19670"
                     /old_locus_tag="STBA_39840"
     CDS             6516..7568
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_39840"
                     /product="hypothetical protein"
                     /protein_id="WP_143659532.1"
                     /transl_table=11
                     /translation="MLGRREFTQLSGATLTAPAWKHLDQSAPGPALLPAMDLVGRIGEP
                     VVRLVEETATHAQRLDDQAGGGALGYITDQAHAVARMLRRDSYDAPTGQRLATALARLA
                     QTAGWMAHESLRDAEAQRWFLIALRAAQAADNRSLGASVLALMSNQAAALSQTKESLQL
                     GAAAQEAAADAPAVVQALVTARSGLVYAAAGDLSGFRRSRDDTLALLDQAAADAQPAPP
                     WASYASSTELDAIAGRCLADLAGRIPTVRLQQRLLAQAEKLLLPRAMDDRPESRRSAVR
                     HSTWLALAHARAGDLDQAIETGERALDRLPEITSARITVLLGQLRDDLALRADRPPIRA
                     FIDRMNRQGA"
     gene            7748..9202
                     /locus_tag="STBA_RS19675"
                     /old_locus_tag="STBA_39850"
     CDS             7748..9202
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_39850"
                     /product="transcriptional regulator"
                     /protein_id="WP_143659533.1"
                     /transl_table=11
                     /translation="MSTAATRSRFQKTCARLRHPVSDDSTVLARYLDELGWSPRQLASR
                     INAIFGAGTVSATAAYYWRRAGNAPRAPLPAMIAIVFSQSLGRTITVEELWNGQAVDSP
                     HIVPAAPDMDVPWTLSGTVQLVEDWVQGGLMDRRTFVAASGAALTAAAHAYLELPRLTA
                     ALRGDTVSGTLISQIEATLPELRDVDHRRGGLHAKTYVHGQWLTIGALVRDGHHQNAIS
                     KRLLSALGEMGDLAGYMAFDAGEHGLAQRYWITALRAAQHAENTALAASILSNMSYQAA
                     TREHGRDAVELANAATRAARTAPAAVRASVASRLATAHAAAGEVQAFRAARDRAQDTLA
                     EASPAAQPVPDWASFVSRSYLSSQSACALIQLGRTQMSENRRVARALLEEGQTLLAPSM
                     SSTPSGFQRSGVLRTVWLALGYTASGELEEACLAGRVAAQRLSDVESPRCASLLTDLRK
                     ALARGRHQNAAVREFIADLDQVLGQT"
     misc_feature    8300..8302
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9424..10053)
                     /locus_tag="STBA_RS19680"
                     /old_locus_tag="STBA_39860"
     CDS             complement(9424..10053)
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571595.1"
                     /locus_tag="STBA_RS19680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39860"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_253194850.1"
                     /transl_table=11
                     /translation="MLTRPFSPLEALITTNPDPILWVKNAVCGLGPYRTDLVETYWQWE
                     QDPGLLVGYGRQAPESLEARTEGMAAQQLGSNIRFSIYDLTNHEKPVLAGVSTLLPDDS
                     VRTAEFEIMLAPEARGRGLGATATKLTLDYAFHVSNLRMVWLKVLAPNKPAVRAYEGAG
                     FRHAGVLRESGYWLGQVCDEVYMDALARDFDGPSAITPVPNLPTHP"
     gene            complement(10001..10735)
                     /locus_tag="STBA_RS19685"
                     /old_locus_tag="STBA_39870"
     CDS             complement(10001..10735)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520044.1"
                     /locus_tag="STBA_RS19685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39870"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_077060510.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 4e-08, bitscore:
                     31.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 1.7e-21, bitscore: 75.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLPTNLTCPTHVRAIDFRHVLVLVDYRTGRVQCLLPAAAAQWT
                     RAARTGTSDGMTPALLQRLLHTGMLTPTSTATPWPTPADAAPTARRSAGTEYLAGASRP
                     PRAPLRASAAAATALAAVFALKHAGDAALAMQRVTTALMAAAVTGEHAATGEQIHAAVL
                     AVRRVGWFSPGRTACLEESAAATLLLASRRLSATWCHGVAPDPVRLHAWVQTADGDPVA
                     EPPTTRAYTPVLTIGGTHHHQP"
     aSDomain        complement(10517..10711)
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_STBA_RS19685_Lasso_Fused_RRE.1"
                     /evalue="1.60E-10"
                     /identifier="RREFam003.1"
                     /label="STBA_RS19685"
                     /locus_tag="STBA_RS19685"
                     /protein_end="73"
                     /protein_start="8"
                     /score="31.9"
                     /tool="antismash"
                     /translation="TCPTHVRAIDFRHVLVLVDYRTGRVQCLLPAAAAQWTRAARTGTS
                     DGMTPALLQRLLHTGMLTPT"
     gene            complement(10732..12549)
                     /locus_tag="STBA_RS19690"
                     /old_locus_tag="STBA_39880"
     CDS             complement(10732..12549)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007457610.1"
                     /locus_tag="STBA_RS19690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39880"
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_077060511.1"
                     /sec_met_domain="Asn_synthase (E-value: 4.6e-34, bitscore:
                     117.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFGGFSAARGAFPRPKGAAPLAPPVSSVWQLGDAPARQIEAPSR
                     RLMLLGWCGASTDELRRAAEAPALPTDVAWRWPGTYTAVEETADRVVLHTDPADAAPVY
                     ATRWGDGWAWSTSARLLARLTAASVDVERLACSILAPSVPALAETRSFFSGVQHLPAGS
                     RIELPADGSGPYCSTRWRPDPVPGPPDHRLREALAAAVAFRVDAGPDLSSDLSGGLDST
                     SLTVLAATCRPRPQPLTAVTMHPDGDDSAADLRYARLTQEYHRDRIDHQVLPVTAEHLP
                     YSDLTAVPASDEPAPSTLSHVQLIRQMRFVHQTGSRLHLTGDGGDSVMGMPPVHLADLI
                     RKGRWLRAVTEAVGLARLRHRPLAPLLREAAALARTGRRDALAALSPMLSCSLGHGPHL
                     GDLSWFSLSPAPSWARPETLRLVAGAALGAAERDEELPGTDIAVRTLVDEIRETARSAV
                     ADAALAASVGVDLHNPFLDGLLVDAVLRTSIDHRPAVHAYKPVLRRAMAPWLPPALARR
                     TTKDSATASHYAGLRANLSVLMELADGRLAALGLLDPPQLRRHLREAAAGIPTSLGPVE
                     QALSAEAWLHAHHTHPAPAWTDAPVGSVR"
     misc_feature    complement(11917..11919)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12655..12783)
                     /locus_tag="STBA_RS37870"
                     /old_locus_tag="STBA_39890"
     CDS             complement(12655..12783)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033525.2"
                     /locus_tag="STBA_RS37870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39890"
                     /product="albusnodin family lasso peptide"
                     /protein_id="WP_171987740.1"
                     /transl_table=11
                     /translation="MNELLNTETTTIDEELVEIGDATTLTRGGDGFGRENKRRIYG"
     gene            complement(13293..>13582)
                     /locus_tag="STBA_RS19695"
                     /pseudo=""
     CDS             complement(13293..>13582)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007379643.1"
                     /locus_tag="STBA_RS19695"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GIVQRLLDPLPSGSALAVSHCTPDFDPKTWARVAGIYRDGARRRR
                     YAPAARSSGSSRDSTWSTPGWRLRTAGFRTFRFRRSMTPP"
     gene            14025..14762
                     /locus_tag="STBA_RS19705"
                     /old_locus_tag="STBA_39900"
     CDS             14025..14762
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_39900"
                     /product="hypothetical protein"
                     /protein_id="WP_143659534.1"
                     /transl_table=11
                     /translation="MAIETVAMDAIRPYPGNARLGNRKVIGTSLSKLGQYKPVIVQRST
                     GHILVGNNTYLTAQDQGWQEIAVQWVDVDDVRAREINLIDNRSNDLATGYDEKLLLQLL
                     EDVPDLSATGYAEEDVEALLRATDAIGNSATDFLTPFLTPAAPAAPAAGSATRPVGPDT
                     SSGQPRSAEASPQDGTDTATEPDGTPDSPAQQNLYVPVSWTVSVAERDEIRAALRAAQG
                     HWQLATASDALLAVVRFFTQRQE"
     gene            14766..15215
                     /locus_tag="STBA_RS19710"
                     /old_locus_tag="STBA_39910"
     CDS             14766..15215
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019498.4"
                     /locus_tag="STBA_RS19710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39910"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_077060514.1"
                     /transl_table=11
                     /translation="MPLKIVNLEKTALRILTEGLAAFGADATFTPLHTNGALGADMLRV
                     APGDAFPVHTHPGDHLLLCVKGTGTISVGGTTYTVGPGDLYMVPGTVPHAVGAAENDEH
                     ILLAIGAPHFPVDSPERLMYTDWQGNPLTEAYFHQDDVSEGRRHP"
     gene            15212..16015
                     /locus_tag="STBA_RS19715"
                     /old_locus_tag="STBA_39920"
     CDS             15212..16015
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013658.4"
                     /locus_tag="STBA_RS19715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39920"
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="WP_077060515.1"
                     /transl_table=11
                     /translation="MTSSPSSLRRKQGIPDPAAWLQARATARELWPDDRLDALVDRTAA
                     EITRTIRGKRTALAWSGGKDSLALQLVAAQAGITEAVLAISELEYPAFLQWVTDYMPDG
                     LTVVSTGQDLDWLAAHPEMLFPQGRYGTRWFTIVNHRGQERYFRDQNLDLLLLGRRHAD
                     GNYTGPKGSMIYTNSRGITRYSPLAAWPHEAVFALLERHQVVLPPCYDWPRGYQVGTGA
                     WPARQWTTSVDHGFDEVWQIDPEVIRQAAPTLPQAADWLARTGRA"
     gene            16018..16605
                     /locus_tag="STBA_RS19720"
                     /old_locus_tag="STBA_39930"
     CDS             16018..16605
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_39930"
                     /product="hypothetical protein"
                     /protein_id="WP_077060516.1"
                     /transl_table=11
                     /translation="MCGIFAYTGRRAPDVELLTEAARYAARRGPHAHGWAGPDTPPHRA
                     LGPLDPEDCRKITGRAVLGHARMATVGPPTLVDGIQPIDADGHLIAYNGTVTNPGDLAP
                     ELCPTDTIAVARAYARHRASGEGTRAALSAVLEVARARSWALVILDRTGQVLTHRHRLP
                     LFRCTTTDGIYLSSGRFTPEATPTPENTITQE"
     gene            16609..17937
                     /locus_tag="STBA_RS19725"
                     /old_locus_tag="STBA_39940"
     CDS             16609..17937
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1221: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013658.4"
                     /locus_tag="STBA_RS19725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39940"
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="WP_077060517.1"
                     /transl_table=11
                     /translation="MRGTSHVRPRIELDKNVYDLALERTAYVMDVFDEPIVAFSGGKDS
                     TAVLNIALEVAHSSPRYRRHLPLRVVHWDEEAIPYETEEYVRRIAQRDDVALDWFCLPV
                     QHRNACSRTHPYWWPWAPEDRDKWCRPLPPEAITHLDGFPLNPPEARPSAPAMNGLLAP
                     GKASTVMLMGIRAQESITRTRAVSRKAVDNYIIPYKDGPSNGNLSKAYTVYDWRTEDVW
                     TAPALRGWDYNRAYDRMEMAGVSASQQRCSPAFGEEPLQKIHTYATCFPDVWERMSERV
                     PGIGAAHRYALTELYCYRDRPEKPVGMAWPDFLAHYVAKFTPEAQAKVSDRLRLIIRRH
                     YRKTTDPIVVKAKHPETGVCWDYLLMIAMRGDFKNRKQEGAGFGVPMPRLWSRYASELV
                     RLIDDGAGPELGHPRPLPSDPYALIPPAYRAGGQDPRDGSPDR"
     assembly_gap    18078..19063
                     /estimated_length=986
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            19255..19563
                     /locus_tag="STBA_RS19730"
                     /old_locus_tag="STBA_39950"
     CDS             19255..19563
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_39950"
                     /product="hypothetical protein"
                     /protein_id="WP_077060518.1"
                     /transl_table=11
                     /translation="MSYTHGPLPQWDAVGGYGSGTFEAGDPHGAVWRLWLVERPADSDP
                     LPPGYRLAPRDNLTNPTFVTREHGLYYAMDAAGMRIAADAVRADPEGAARQLGLDGE"
     gene            19854..20336
                     /locus_tag="STBA_RS19735"
                     /old_locus_tag="STBA_39960"
     CDS             19854..20336
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.4"
                     /locus_tag="STBA_RS19735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_39960"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_171987741.1"
                     /transl_table=11
                     /translation="MALYRDSVLRPDGAAGTYEHVVVEDGVRVVALDDDGQVVLVEDDF
                     YLQQRRVLHLPGGGRGGQDPQAAAIRELGEETGLVAGEMRPLGVIDPLPATTGARTHLF
                     LATALRLGRTHRDETEIGMTVQRWKLTAAVEAVRAGRITEAGSVAALFLAEHVARA"
     gene            complement(20346..20777)
                     /locus_tag="STBA_RS19740"
                     /old_locus_tag="STBA_39970"
     CDS             complement(20346..20777)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_39970"
                     /product="hypothetical protein"
                     /protein_id="WP_143659535.1"
                     /transl_table=11
                     /translation="MTIALRAPVSANGVDGDDEDRVIGASVEHSIHVDRALSDLLTALE
                     PNHPLAFPVFEARSAVLELSLLREHWVTYCGERARPDADETGLGLDREFPAPARVRAWP
                     LYNTARRRTERLNAHLVRLQAELADFTGHDITGRQRPAA"
     gene            complement(21271..21585)
                     /locus_tag="STBA_RS19745"
                     /old_locus_tag="STBA_39980"
     CDS             complement(21271..21585)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS19745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_39980"
                     /product="hypothetical protein"
                     /protein_id="WP_077060521.1"
                     /transl_table=11
                     /translation="MTAETKPQTSVLPEIFSALEPLFADPHTIDRAKRLGEVLNAIPEL
                     QKALRDARSEDVNHLKDSGQMTYDEQAAALNLTYASVARIANGGRSGKEYAKAKKQSGG
                     "
     assembly_gap    21656..22243
                     /estimated_length=588
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
ORIGIN
        1 gggacgggca tcacccacct gtccgggatc agcaccaccg cgcgaatccc tccgtacggg
       61 gactccccga gatcaacccg gaacccatgg cggcgcacgt actcacccac gaccgccagg
      121 cccagcttcg gcacctcgga caaggcgccc agatccaccg gccgctcccc ggacacccgg
      181 gcacgcgcgg cctgcagcga ggcgtcctcc atccccgcac cgctgtcgtc gacctcgatg
      241 accacgcccc gctgcaccag acgcaccgtc gcccgcacct cgaacgccgg cggcgaacac
      301 gccgcggcgt tactcaacag ctcggcgaga aggtggatca gcggctccac cacctccgcc
      361 gccacaccca cctcgtggtg cccttccacc cgcacccgct gatacgcctc gatccggccc
      421 gacgcagacc gcaccgcatc caccaccgcc agcggctcct gccagcgctg ccccgggaac
      481 gccccgcaca cgatccgcaa gctctgagcc agcctcgcct ggaccgtcgt cgcgtgatca
      541 acacgcagcg ccgcctctgc cgccttctcc ccgacagccg ggtcgtccag caacggcgca
      601 acggcctcct ggatacggtg cgcacccgcc tgcacgcgtt cacccaccgc gaccgtcaca
      661 cggcggagag actcctcacg gtcgtggacc acagcgacga catgcccagg gatcttctcc
      721 agccagccgg ccacagactc acccaggaaa ccggcccgca gttgaggcgg cacatcacca
      781 cccgccgcgg caaccgggag ccgcacctcc accaggtgcc gcaactcctc ctgcagcgcc
      841 gcggctgctg tatccctctc ctgctgccaa gctgcgtcac gacggcgcat ctccgccaac
      901 tcggtctccc gtgcacggat gtcgccccgt gccgtcttca gggcacgttg ccgctgccga
      961 gccacccacg cgaaccacac ggccgccatg gcacaggcca cagcagccgc gagcaggaga
     1021 tacggcgtca tcgagtcctc acagtcagcg tctacaaaat gggggtgaag ggccgccggg
     1081 gcactccccg tcccgttccc gacggggggc gggcacggaa agaggagttc gtctcttccc
     1141 cggcggccgg tcgaaaggtg agctgcgctt caggcttcgg gaatggtcac ggtttgaagc
     1201 cgacaccagc ccacaagctc accgtggcgt cattgacctc cgggcccggg aaatggcggc
     1261 gaggcacctc ctcggggtcc ggacgccacc ggtgcgcgac ctccaacccg ggctccgcca
     1321 agtcaagtcc ctcgaagaac cgctcgacct cgcttcggct gcggacctgc gctggcgtgc
     1381 ccccggcacg gtagatatcg acgacccgcg cccaggtctc cggatcgaaa tcaggcgtgc
     1441 agtggctcag agccagcgcc gagccagagg gcagagcgtc cagcagtcgc cggacgatcc
     1501 cgtacgggtc cgattcatca ggcacgaagt gcagcaccgc gtgcaggctc aacacgatgg
     1561 gctggcacag atccaaggtc gcggtgagct gcggtgcggc gaggatccgc tccggatgac
     1621 gcacatcggc ctggatgtaa gcggtacgtc cctccggcga gctgttcagc agtgcgcgag
     1681 cgtgcgcgag gacgatcggg tcgttgtcga cgtagacgac gcgaacctgt ggttcgacgt
     1741 cctgggcgac ctcgtgcagg ttcgggctgg tggggatacc ggtgccgatg tccagccact
     1801 ggcgcatgcc gtgctgggcc acgagcatcc gggtcacccg gtgcatgaag tgacggttct
     1861 cccgggcaca gacggagatg cccgggaaga ccgcttcgac ctgccgagcg gcctcgcggt
     1921 ccggggcgta gttgtccttg cctccgaggt agaagtcgta catgcgggcg gagtggggga
     1981 tgtccagcct caggtccagg ggcatcgtgg cgtgcgtgct gtcgggtgtg tccggctggt
     2041 cgttcatgcg ggtaccaatt tcgtgatcgt ggtatcgaca gccgacggcg cgaggggtgg
     2101 ccgggaagtg ggccgcaggc gggggtactc gctcgggccg caccgcacga gccggggagc
     2161 ggaggagcat aggcccgacc gccagcagca cacgagtcac aaccgcggcc cgaatccagc
     2221 gggcacgatt ccccggaaga aacgcgcctc cgcctgccgc tcggacccgg tcgcgaacag
     2281 ggcctcggtc aggccgtaag gctccgtcag cccggggcac tccctggccg gtccaggcag
     2341 cagccacatc tgcgcgtcgc accgacgacc accgccgcac tccaggaccg gccgactccg
     2401 ccaccggccg accggcacag gctcctcgac cggtactgcc agcgtgcgat gcctgcggca
     2461 cagccgcacc ggccccacgg tcccgccccg cccgcgtagc cagcacagcg ccaccatccc
     2521 ctccgattcg cccaggtgca cgacctcggg ctgccgtccg tccagcacgc tcggaagcgc
     2581 tatgtagtcg ggcggaacaa gccagtcgat ggcagtcatc aggaatcagc ccagacagaa
     2641 gagggggtat tcggcgcgca cggatgccga ccgccgcgcc gcgccggcgg agcggccgcg
     2701 cgttcagcgc tggcatccgg tgtcgcttca tcacaacaaa tccctagaaa aggaaggaag
     2761 agagggaagg gaaggccgcc gggacagggg tgcggcgctc tgccaagggg gacttgggag
     2821 cggtcccggc ggccggtcat acggggtggt gctgcgccta ctcgccggct acggatccgt
     2881 ctgcgggaac ggagtgccga acacacgccc ttcggacatg aggtccagcg cgttcagtgc
     2941 cggcgcccgg ctccgcatcc agcgttttcg ccgcctatcc ccggccgcca gcgagatgac
     3001 caccttgtga gggggggcca ccgcgccccg gcccgcgctc tcactggtca cattcgcccc
     3061 ttccacggtg aggagtgact cgctccggcc cgaaccggcc ggaaaccagg tcagtagcgt
     3121 taccgactcg caccgtgggc ggaagcggtt gcccggcgcc aaccagtgcc ggaaggcgcc
     3181 ccgcctcagg caacccctgg ctgccaggcg cctggtgttg cccggcgccc ctgcggccgc
     3241 gcctcgtggc ggcagccctg tcagcctcgc ggcgccggtc gccgcactgc ggcgatggat
     3301 gcctccgggt gcagccgggt cgtggtgcct catctcaagg tcctcacacg atcgcgaatg
     3361 acgggggtgt tgactggcgg cgggacgttc cctggtggaa aggcagttga gtcgagcacg
     3421 gtctcagcgg ccggtcggag gtcgaaccaa gacggcccgc cgaagccgtc gtcacgacgg
     3481 atgccatgcg gcctctcggt ccgggacgta cagccagcgt tcgcgccacg gacagggtgc
     3541 tcacctgcga ccaggtgatg acgagaccgg tcacggcacc ctcccctcct cgttaaccga
     3601 cagggggacg acatcccccg gcagccatcc ggagcgaagg cggaggtggt tggcggtcgt
     3661 gacgcagagc gtctcttgct gtccgctgac tggtgtgacg ctcgcctgtt caccgcaacc
     3721 cacgcctcac atggagtgac tgcgcgacgg ctcatagcta accggaggcg tgccaagggg
     3781 gctagtgccg ggttgtcttc tccttgtctc ctcttcgcgc acggcgtcgt atcggcagac
     3841 cagccgtgac gtagggcgtt agagtcgtca cgcgaaggga agggggaagg gatgtcgcgc
     3901 cttgcgcagg tgacttcggg aatctacgtg cacccgctca gttatgtacg agccgagcgg
     3961 ggctggaccc agcaagatgt ggttgacgtc atcgccgaac gggtcggtgg ctctgcccga
     4021 cgcaacaagg cgtggctctg ggagaaccgg aacgtcgtac ccgactggcc cagtcaggtg
     4081 gcgctggccg ccgaactcgg tatccctgaa tcccggcttg tggaagagcc ctggccgcag
     4141 tggctgcctg atggggaccc catccgcaca gacttcgcat ggtcgcagac gggcagcatc
     4201 caagccttgg aagacgtact ggagcacggt gtgcgtgatc gccgcggatt catgaaactg
     4261 accggttccg ccctggtcgc cctggcacac gactggctgc gagccgaacc cgccgagctg
     4321 gttgccgccc tccgcggcgg ccgcgtggcc gacacattcg tggaccgcct ggaggaaggg
     4381 cttccacgcc tacgcttcct ggaagcggaa cgcggcggcc aggaggcacg ccggttgatc
     4441 gatgccgagt tgggcctggt ggccgaggta ctggccaact cctcctacac catcgaaacc
     4501 ggcaggcggc tgtacgccct ggcgggcgaa ctcggccgga tggcgggctg ggcgagcttc
     4561 gacgccggcc tgcacgccgc cgcccagcgg tactgggcgg cggccatcca cgccgcccac
     4621 gctgcggatg accgtccgct gggcgcgaac atcatgaaga gcatgagcct tcagtgctac
     4681 gacttcgccg accccgccga agcactggcc ttggcccgaa gcgcctacga gggcgccagc
     4741 gacaccaccc cgcgcactgt ggccatgttc gctctgcggg aggcccgggc ccacgccgcc
     4801 ctcggcgatc tctcggcctg cgaacgcttg ctgggcgagg cggagagcgc cgtctcgcgg
     4861 gcggacaccg cggtggaccc tgatcccgcg tggatcggct acttcgatga cgcggaattc
     4921 tatgcacaga tcggtacctg ctacctcgac ctcggcacca ggcacggcga ccgcaggcag
     4981 ttcacccggg ccgacaccta tctcgcgaaa acgctccgcc tgctccccga aacgaaggtg
     5041 cgcgaccgcg cgacctacct cacccgccgc gcctcggccc agacccagct cggcaacctc
     5101 gatcgggcct gccagctcct gaccgacacc atccccctcg tccattcggc accctcccag
     5161 cgcaacatcc ggcgcatgtt cacggtgcgc aaccgcctcc ctctgaacag gcgtgacgcg
     5221 cgagcccgcg ccctggacga acacctgcgg gtgttgacga acgcctcatg accgaactcc
     5281 agcgcgtcgc cctggtgacc ggcgccaacc ggggcatcgg tctggccatc gcccgcggcc
     5341 tcgcccaacg cggcctgcac gtcgtactcg gcgcccgaac cgaagcagct gccgaaacgg
     5401 aggccgccgc gctgaccgcc gacggcctcg ccgcctccgc gcaccagctg gacgtgaccg
     5461 atcccgtcag cgtcgcccgt gcggcggccg acaccgccaa ccagctcggc cgcctcgacg
     5521 tcctggtctg caacgccggc gtcgccatcg accgcgggca acccgccagc agcccggact
     5581 tcgagaaggt acgcgccacc ttggaggtca acctgctcgg cgcctggcgc tgctgcgctg
     5641 ctgccatacc cgagatgcgc aagcacgact acggccggat cgtcaccatc accagccacc
     5701 tcggctcgat caccaccatg gccgacacca acgtcggcta ccgcgtctcc aaagccggcc
     5761 tgaacgccct cacccgcata ctcgccgcag aactggacgg cagcggcatt ctcgtcaacg
     5821 ccgcgtcgcc gggacgtacc gacacacgca tggcctaccg cgagaccgac cgcacgcctg
     5881 aagaagccgc cgataccccg atctggctgg ctaccctccc cgacgacgga ccaagcggcg
     5941 ggctcttcta cgagcgaaag cccctggcct ggtaacgctt accgccatct cacgcaccat
     6001 ggcaaaccag ccgccgcaac aaggcggtga tgttatcgat accatctgta acagaagcag
     6061 cggtcagcgt ctgcggccag cgagcagagc gatgtgcttg cgggtcagcg ggggcggggt
     6121 gaacccgggg ggggatcatg gcggagacct tcggccaggc actgcggcgc ctgcgcggtg
     6181 atctctcgca acgcagactg ggggaacgcg tattctgcca taaatcgcac atttaccgcc
     6241 tagaggtagg gctgcggggc ccgtctcccg acatggccga acggctggac cgcgaactgg
     6301 cggccggagg acacctcatc caactcgcct gtcagatgga cgaagaagtc ccgccgcagc
     6361 ccatgcccgt cactgcggag acagctgttg cgggccgcgc agcccgccgg ccaccggcgg
     6421 cgtcgccgtc ctcgacgcgg tcggtggcac ttccggccga tcacggactg gacctaccct
     6481 ggagcaggca gcttccgacg cagtgggtgg tggacatgct ggggcgacgg gagttcacac
     6541 aactctccgg cgccaccctc accgcaccgg cctggaagca tctcgaccag tcggcccccg
     6601 gcccggcact gctccctgct atggatctcg tcggccgcat cggcgagccc gtggtccggc
     6661 tcgttgagga aaccgcgaca cacgcgcagc gacttgacga ccaagcgggc ggcggagctc
     6721 tcggctacat caccgaccag gcccacgcgg tcgccagaat gctgcgccgc gacagctacg
     6781 acgcccccac cggccagcgc ctggccaccg ccctcgctcg cctcgcgcag accgcagggt
     6841 ggatggccca cgagtcactg cgagacgccg aggcccagcg gtggtttctc attgctctcc
     6901 gcgccgctca ggctgccgac aaccgctcgt tgggcgccag cgtgctggcg ctgatgtcca
     6961 accaggccgc ggccctgtcc cagaccaagg aatccctgca actgggcgcc gccgcccagg
     7021 aagccgctgc cgacgcgccc gccgtcgtac aggccctggt gaccgcgcgc agcggcctgg
     7081 tctacgcggc cgcaggcgat ctctctggct tccgccgtag ccgcgacgac accctcgccc
     7141 tgctcgacca agcggccgca gacgcgcaac ccgctcctcc ctgggcctcc tacgccagca
     7201 gcaccgagct tgacgccatc gccggccggt gcctggctga cctcgccggg cggataccca
     7261 ccgtccgtct ccagcagcgt ctcctggccc aggccgagaa actactactc ccccgcgcga
     7321 tggacgaccg gcccgaaagc cggcgctccg ccgtgcgcca cagcacctgg ctcgccctcg
     7381 cccacgcccg cgcgggcgac ctcgaccagg ccatcgagac cggcgagcgg gccctggacc
     7441 gtctgcccga gatcacctcc gctcgcatca ccgtgctgct gggccagctc cgcgacgatc
     7501 tagccctcag ggccgaccgc ccccccatcc gcgccttcat cgaccgcatg aacagacaag
     7561 gggcgtgacc ggtccgctac cgcgccctcc tcgaacagtc cggacggctc gtgttggacc
     7621 gctgcttcct cagcgagaca ccaaactgtc ccacccacgt ccaccggcag ctacgagggc
     7681 ctgccctcgg cgtcccagct gccccaccgc gcggaagcac gtcccggcaa cacccatctt
     7741 cagctgagtg agcacagcag ccacccgttc ccgattccag aaaacttgtg cgaggttgag
     7801 acatccggtg tccgacgatt ccactgtcct ggcccgctac ctggatgagc tggggtggtc
     7861 accccggcag ctcgcctccc gcatcaacgc catcttcggg gctggcactg tgtcagccac
     7921 cgcggcgtac tactggcgcc gcgccggaaa cgccccgcgc gcaccgctgc ccgccatgat
     7981 cgcgatcgtg ttctcacagt ccctcgggcg aaccatcacc gtggaggagc tctggaacgg
     8041 tcaggccgtc gactcccccc acatcgtccc cgcagccccg gacatggacg ttccctggac
     8101 cctctcgggt accgtccaat tggtagagga ctgggtacaa gggggtctta tggaccgccg
     8161 gacgttcgtc gccgcatccg gtgcggcact caccgcggca gcccacgcct acctggagct
     8221 gccgcgcctg accgccgcgc tgcgaggcga caccgtgagc ggcaccctga tatcgcagat
     8281 cgaggcgaca ttgcccgagt tacgagacgt agaccaccgc cgcggtgggc tgcacgccaa
     8341 gacgtacgtt catggccagt ggctcaccat cggtgcgctc gtccgtgacg gccatcatca
     8401 gaacgcgatc tcaaaacgac tgctgagcgc cctcggcgaa atgggcgatc tcgctggata
     8461 tatggctttt gatgccggag agcacggtct ggctcaacgc tactggatca cggcccttcg
     8521 ggcggctcag cacgccgaga acacggcact agctgccagc atcctgagca acatgtccta
     8581 ccaggccgcg acccgtgagc acggccgcga tgctgttgag ctcgccaacg cagcaacccg
     8641 agcggcgcgc accgccccgg ccgcggtgcg cgcatccgtc gccagccgcc tagccacggc
     8701 acatgccgca gccggcgagg tacaagcctt ccgggcggct cgtgaccgtg cccaggacac
     8761 cctggcggaa gcttcacctg ccgcccagcc tgtccctgac tgggcaagct tcgtctcaag
     8821 gagctacctc tccagccagt ccgcctgcgc actcatccaa ctcggccgta cgcagatgag
     8881 tgagaaccgt agggtcgccc gcgcacttct ggaagaagga caaacgctcc ttgctccctc
     8941 gatgtcttcg acgccgagcg gctttcagcg ctccggagtc ctgcgcacgg tctggttggc
     9001 ccttggctac accgcatcgg gcgagctgga ggaggcgtgc ttggcagggc gcgtcgcagc
     9061 ccaaaggctc agcgatgtcg aatccccccg gtgtgcctct ttgctcaccg accttcgcaa
     9121 ggctctcgcc cgcggccggc accagaatgc agcggtacgg gagttcatcg cggacctgga
     9181 tcaggtcctg ggccagacct gacaaccgca cacgccgctg tcacggtgct ccggcgggca
     9241 gtgaccttcc cagccgtctc tcgctagtcc ccgccccaga cgagcggcag ccctgagttg
     9301 tacaccgcgc tagctgttct gtccatggaa ggtcaatcac gtaacgccag ctactcgctg
     9361 ttaaagcaga gttggggcac acgtgcgtgt gcgcccccgg ggtgggggcg cacggcgggc
     9421 gggctacggg tgcgtaggca ggttgggcac gggtgtgatg gcggacggcc cgtcgaagtc
     9481 ccgggcgagg gcgtccatgt agacctcgtc gcagacctgt ccgagccagt acccggactc
     9541 acgcaggacg ccagcatggc ggaagcccgc gccctcgtag gcgcgaacgg cgggcttgtt
     9601 cggggcgagg accttcaacc agaccatccg caggttgctg acgtggaagg cgtagtcgag
     9661 ggtgagcttc gtcgcggtgg cgcccaggcc tcggccacgg gcttcggggg cgagcatgat
     9721 ctcgaattcc gcggtccgga cgctgtcatc aggcaggagt gtgctcaccc ctgccaggac
     9781 aggcttctcg tggttcgtca ggtcgtagat gctgaagcgg atgttggagc cgagttgctg
     9841 agcggccatg ccctcggtcc tggcctccag ggactccggg gcctggcggc cgtatccgac
     9901 caggagcccg gggtcctgct cccattgcca gtaggtctcg accaggtcgg ttcggtacgg
     9961 gccgagcccg cagacggcgt tcttgaccca caggatcggg tcagggttgg tggtgatgag
    10021 tgcctccaat ggtgagaacg ggcgtgtaag cacgggttgt tggtggttcg gccactgggt
    10081 cgccatcagc tgtttgcacc caggcgtgca gccggacagg gtcgggggcg acgccgtggc
    10141 accaggtggc ggacaggcgc cgcgacgcga gcaggagggt agcggcggct gactcttcca
    10201 ggcaggcggt tcgcccgggg gagaaccagc cgacgcgtcg tacggcgagg acagcggcgt
    10261 ggatctgctc gccggtggcc gcatgttcac cggtcactgc ggcggccatg agcgcggtgg
    10321 tgacacgttg catcgccagc gcggcgtccc cagcgtgctt gagagcgaag acggcggcga
    10381 gcgcggtcgc tgccgcggcg ctggcgcgca gcggggcgcg cggggggcgg ctggctccgg
    10441 cgaggtattc ggtgcccgcg cttcgccgag ccgttggggc tgcgtcggcc ggtgtcggcc
    10501 acggcgtcgc ggtcgatgtc ggggtgagca tgcccgtgtg cagcagccgc tggagcagag
    10561 ccggcgtcat gccgtctgag gtgccggttc gggccgcgcg ggtccactgc gcggctgcgg
    10621 ccggcagcag acactggact cggccggtgc ggtagtcgac gaggaccagt acgtgtctga
    10681 agtcgatcgc acggacgtgg gtgggacagg tgaggttggt gggcaggtca ctcaccggac
    10741 gctcccgacg ggggcgtcgg tccaggctgg ggcggggtgt gtgtggtggg cgtgcagcca
    10801 tgcctcggcg ctcagcgcct gttcgacggg accgagcgag gtggggatgc cggcggcggc
    10861 ctcgcgaagg tggcgccgca actgcggcgg gtcgagaagc ccgagggcgg cgagacggcc
    10921 gtcggccagc tccatcagga cagagaggtt tgcgcggagc ccggcgtagt ggctggcggt
    10981 ggcgctgtcc ttggtggtgc ggcgggcgag ggcgggcggc agccaggggg ccatggctcg
    11041 gcgcaggacc ggcttgtagg cgtggaccgc cggtcggtgg tcgatcgatg tacggagcac
    11101 ggcgtccact aggagcccgt cgaggaacgg gttgtgcagg tcgacgccga ccgatgcggc
    11161 cagcgccgca tcagcgacgg ccgaacgggc ggtctcccgt atctcgtcca ccagggtgcg
    11221 caccgcgatg tccgtgcccg gcagttcctc gtccctctcg gccgcgccga gtgccgcgcc
    11281 ggccaccagc cgtagcgtct cgggtcgggc ccagctgggc gcgggcgaga gggagaacca
    11341 gctcaggtcg cccaggtggg ggccatggcc gagggaacac gaaagcatcg gggagagggc
    11401 ggccagtgca tcacggcgac cggtgcgggc cagtgcggca gcctcgcgca gcagcggcgc
    11461 gagcggccga tgccgcaggc gggccagacc cacggcctcg gtcacggccc gcagccaccg
    11521 gcccttgcgt atcaggtcgg cgaggtggac tggaggcatg cccatcacgc tgtcgccgcc
    11581 gtcgccggtc aggtgcagac ggctgcccgt ctggtgcacg aaacgcatct gcctgatcag
    11641 ttgaacgtgg ctgagagtgg aaggggccgg ttcgtcgctg gcagggacgg cggtgaggtc
    11701 gctgtacggc aagtgctcgg cagtgaccgg aaggacttgg tggtcgatcc ggtcgcggtg
    11761 gtactcctga gtcagccggg cgtagcgcag gtcggcggcg ctgtcatcgc cgtcggggtg
    11821 catcgtgacc gcagtcaggg gctggggccg ggggcggcag gtcgcggcca ggacagtaag
    11881 actggtggag tccaggcccc cggacaggtc gctcgataag tctgggccgg cgtccacgcg
    11941 gaaggcgact gctgccgcca gggcctcgcg caggcggtgg tccggcgggc cgggcaccgg
    12001 atcgggacgc caccgcgtgc tgcagtacgg gccgctgccg tcggcgggaa gttctatccg
    12061 gctgcccgcc gggaggtgct gcacaccgga gaagaagctg cgggtctcgg ccagagcggg
    12121 cacagaaggc gcgaggatcg agcaggccag ccgctcgaca tcaacactcg ctgcggtgag
    12181 cctggccagc aggcgggcgg aagtggacca cgcccagccg tcaccccagc gggtcgcata
    12241 caccggcgcg gcgtcagcgg gatcggtgtg gagcactacg cggtcggctg tttcctccac
    12301 cgccgtgtac gtccccggcc agcgccaggc gacatcggtc ggcagcgcag gggcctcggc
    12361 cgcacgccgc agttcgtcgg tggaggcacc gcaccagccc aacagcatca gccgcctgct
    12421 gggggcctca atctggcggg cgggggcgtc gccgagttgc cacaccgacg acacgggcgg
    12481 cgcgagcggc gcggcgccct tggggcgcgg gaaggcgccg cgagcggcgc tgaaaccgcc
    12541 gaaagccatg aacttccttc cgtacagggg gagtgcgtgt cgtacctgcg gtggtgcggc
    12601 caccgggcca gcagtgagcc agcgcccggg ggccgcacca cgtctcgggg taagtcagcc
    12661 gtagatgcgg cgcttgttct cccggccgaa gccgtcgccg ccccgggtca gcgtcgtggc
    12721 gtcgccgatc tcgaccagtt cctcgtcgat cgtggtcgtc tcggtgttca gcagttcgtt
    12781 cactggttca ctcctctttc cagaagggac atacgggaat ccattgcaag gcggagcgga
    12841 aacgaatgat cgctccgtgt gatcatcaga tcgtgtcgcc gacgactgct gccagaaggc
    12901 tggggcgtaa aagctgtaaa agtgcgcggg aatctttctc ctggcatgcg aaccaggagc
    12961 ccctgccaac ccagcgcccg tgcaggcgga cggccgtgcc gtgctgctcg gtggttctgg
    13021 tgggaaggga ggatccggcg atgaccgggc ggcggcccgc gagggagagt cggaggaggg
    13081 ctgtgctgcc cgtaccgatc ttgacctgcc cgccgccaga ccgcagccga tcaccgaact
    13141 accggcggaa ggcgacgtgc cgtgaccgcg cctgacggcg ccccgacgcc ggggattgca
    13201 cacctggtcc gtccccgacg ggggcgggca cggaccggag cttccccggc ggccagtcga
    13261 agagcgagct ggcgatcgct tcccgaggcg aatcagggtt tgaagccgac gccagcccac
    13321 aagctcacgg tggcgtcatt gacctccgga acctgaaggt tcggaagcca gcggtgcgca
    13381 acctccaacc cggggtcgac caggtcgagt ccctcgaaga accgctcgac ctcgctgcgg
    13441 gcgcgtacct gcgccggcgt gccccgtcgc ggtagattcc ggcaacgcgc gcccacgtct
    13501 tcggatcgaa atcgggcgtg cagtggctca cggccagcgc cgagccggag ggcagagggt
    13561 ccagcaggcg ctgcacgatc cccaaggtcc tcttagctca gcgaagatcg ttgacgcagc
    13621 agacggctga ggaggccgaa gtccagagtg cttaacgccg cgcgcacccc cgagtcctcc
    13681 cacacatgac cgggaagtct cgcaggagtt acccgtggct gactcgccgt ctccccagcg
    13741 tgcttcggtg gccggaagcc aagctcgatg cacggcttcc cgaacgtggc ctccagcacc
    13801 acgcgcaccg gatgacgtgg ccagggcggg gaccgagacc gaaagggtga aggccagggc
    13861 ctgcgtcgtg cgctcccacc gttcacggct gccttcgtct tccgaaggct ccgtacacac
    13921 ccctaccctc cttggccgca gatcggcaga aggaggccgg ggtgtcgagt cagcgcgcgc
    13981 aggagaacac cggaacgaac gaaccagcgg gtcgcattct caccatggcg atcgagacgg
    14041 ttgccatgga cgctatacgc ccctacccgg ggaacgcccg tctggggaac cggaaggtca
    14101 tcggcacctc gctgagcaaa ctcggccagt acaagccggt catcgtccag cgctctaccg
    14161 gccacatcct cgtcggcaac aacacctatc tgaccgcgca ggaccaaggc tggcaggaga
    14221 tagcggtcca gtgggtggat gtggatgacg tacgcgcccg cgagatcaac ctcatcgaca
    14281 accggtccaa cgacctggcg actgggtacg acgagaagct gctccttcag ctcttggaag
    14341 acgttccgga cctgtccgcc accggctatg ccgaagaaga cgtcgaagcg ctgctgcgcg
    14401 ccaccgacgc catcggcaac tcggccaccg acttcctcac gcccttcctg acgccggccg
    14461 cccccgctgc cccagcagcg ggctcagcca cgcgacccgt cggtccagac acttccagcg
    14521 gtcagccccg ttctgcggaa gcctcaccac aggacgggac cgacacggcc accgagcccg
    14581 acggcacccc ggactcacca gcgcagcaga acctctacgt gccggtctcg tggacagtca
    14641 gcgtcgccga acgcgatgag atccgcgcgg ccctgcgtgc cgctcaaggc cactggcagc
    14701 tcgccaccgc ctccgatgcc cttctcgccg tcgtccgctt cttcacccag cgccaggagt
    14761 aacccgtgcc gctcaagatc gtcaacctgg agaagaccgc cctgcgcatc ctcactgaag
    14821 ggctcgccgc cttcggagcg gacgcgacct tcacgccgtt gcataccaac ggtgcgctcg
    14881 gcgcggacat gctgcgggtg gctcccggcg atgcctttcc cgtgcacacg cacccgggcg
    14941 atcacctgct gctgtgcgtg aagggcaccg gcaccatcag cgtgggcggc accacctaca
    15001 ccgtcgggcc cggcgacctg tacatggtgc cgggcacggt cccgcacgca gtcggcgccg
    15061 cggagaacga cgagcacatc ctgctcgcca tcggcgcgcc acacttccct gtcgattctc
    15121 cggagcgcct gatgtacacg gactggcagg gcaacccgct caccgaggcg tacttccacc
    15181 aggacgacgt cagcgagggg cggcggcacc cgtgacctcc tcgccgtcgt ccctgcgacg
    15241 caagcagggc atcccggacc cggccgcctg gctccaggcc cgtgccacag cccgcgagct
    15301 gtggccggat gaccgcctcg acgcgctggt ggaccgcaca gctgcggaga tcacgcggac
    15361 gatccgcggc aagcgcaccg ccctggcctg gtccggcggc aaggactccc tcgcgctcca
    15421 actcgtcgcc gcacaggccg ggatcaccga ggcggtgctc gccatcagcg agctggagta
    15481 tccggcgttc ctgcagtggg tgaccgacta catgccggac ggcctaacgg tggtctccac
    15541 cggccaggac ctcgactggc tcgcagccca cccggagatg ctgttccccc aagggcgtta
    15601 cggcacgcgc tggttcacga tcgtcaacca tcgcggccag gaacgatact tccgcgacca
    15661 gaaccttgac ctgctgctcc ttggccgccg gcacgccgac ggcaactaca ccggccccaa
    15721 gggctcgatg atctacacca acagccgcgg catcacccgc tactcaccgc tggcggcatg
    15781 gccgcacgag gctgtcttcg cgctgctgga gcgccaccag gtcgtgctgc cgccctgtta
    15841 cgactggccg cgcggctacc aggtcggcac cggagcctgg cccgcccgcc agtggaccac
    15901 ctccgtcgac cacgggttcg acgaggtgtg gcagatcgac ccggaggtca tccgccaggc
    15961 ggcaccgacg ctgccccagg cagctgactg gctggcgcgc accggaaggg cgtgatcatg
    16021 tgcgggatct tcgcctacac cggccgccgg gcaccggacg tcgagctgct gaccgaggcc
    16081 gcccgctacg ctgcccgccg cggcccgcac gcccacggct gggctggccc ggacacacct
    16141 ccgcaccggg ctctcgggcc actcgacccc gaggactgcc gcaagatcac cggccgtgct
    16201 gtactcggcc acgcccgcat ggccacggtc ggccctccga ccctggtgga cggcatccag
    16261 cccatcgacg ccgacggcca cctcatcgcg tacaacggca ccgtcaccaa ccccggcgac
    16321 cttgctcctg agctgtgccc gacagacacc atcgccgtgg cccgtgctta cgcccgtcac
    16381 cgcgcctccg gcgaggggac gcgggccgcc ctatccgctg tactcgaggt cgcccgcgcc
    16441 cgctcttggg cactggtcat cctcgaccgc acaggccagg tgctcaccca tcggcaccgg
    16501 ctgccgctgt tccgatgcac cacgacggac gggatctacc tttcctccgg ccgcttcacc
    16561 ccagaggcca cccccacgcc cgagaacacg atcacccagg aatgaccgat gcgcggcacc
    16621 tctcacgtac gtccccggat cgaactcgat aagaacgtct acgacctcgc tttggagcgc
    16681 accgcctatg tgatggatgt cttcgacgaa cccatcgtcg ccttctccgg cggtaaggac
    16741 tcgaccgcgg tgctcaacat cgccctggag gtcgcgcact cgagcccgcg ctaccgccgg
    16801 cacctgccgc tgcgcgtcgt gcactgggac gaggaggcga tcccgtacga gaccgaggag
    16861 tacgtccgcc gcatcgccca gcgcgacgac gtggcactgg actggttctg cctgcccgta
    16921 cagcaccgca acgcctgctc acgcacgcat ccctactggt ggccctgggc tccagaagac
    16981 cgcgacaagt ggtgccgacc acttcctccc gaggccatca cccacctcga cggctttccc
    17041 ctgaatcccc cggaagcccg cccttccgca ccagccatga acggtctcct cgcccccggc
    17101 aaggcgtcca ccgtcatgct catgggtatc cgcgcgcagg aatccatcac ccggacccgc
    17161 gcagtcagcc gcaaagccgt ggacaactac atcatcccgt acaaggacgg cccctccaac
    17221 ggcaacctgt ccaaggcgta caccgtctac gactggagaa cagaggacgt gtggaccgct
    17281 ccggcgctcc ggggctggga ctacaaccgt gcttacgacc ggatggagat ggccggggta
    17341 tccgcctcgc agcagcgctg ctcacccgcc ttcggcgagg agccgctgca gaagatccac
    17401 acctacgcca cctgcttccc tgatgtctgg gaacgcatgt ccgagcgcgt gcctggcatc
    17461 ggcgctgccc accgttatgc gctgaccgag ctgtactgct accgggatcg gcccgagaag
    17521 cccgtgggca tggcctggcc ggacttcctg gcccactacg tcgccaagtt cactcccgag
    17581 gcccaggcca aggtctccga ccggctgcgc ttgatcatcc gtcgccacta ccgcaagacg
    17641 accgacccga tcgtggtgaa ggccaagcat ccggagaccg gtgtctgctg ggactacctg
    17701 ctgatgatcg cgatgcgggg agacttcaag aaccgcaagc aggaaggcgc tggcttcggt
    17761 gttccgatgc cccgcctgtg gagccgctac gccagcgagc tggtccggct catcgatgat
    17821 ggagccgggc ccgaactggg ccacccccgt cccctgccga gcgacccgta cgcactcatt
    17881 ccgcccgcgt accgggcggg agggcaagat ccccgagatg ggtcgccgga ccggtaaccc
    17941 accccctggt tgccgccgct tctcatgggc ccgtggcctc ctgagcggga aggagaccgg
    18001 gcttcgagat gtccatcagg aggcgactcc ccggacctgg tgccttgacg tcttcgtggc
    18061 tgggtgcgtg aacatctnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnactcccc ttcctctggt
    19081 cggctggctg gcgcgtcacg ggtagctgca cacggatacg gcgcggctgt cccagggagc
    19141 cgggcggtag gtcgtcttcc gcgggcaaga cttcagtagg ttcttcttgc ggcaccgaag
    19201 agttcagtcc gcccctggtc gccgacgtgc gggcgagcaa gagaggaacg ccccttgagc
    19261 tacacacacg gacccctgcc gcaatgggat gcggtcggcg gctacggcag cggcaccttc
    19321 gaggccgggg atccgcacgg cgccgtctgg cgactgtggc tggtcgagcg gcccgccgac
    19381 agcgatccgc tacctcctgg gtaccggctc gccccccgtg acaatctgac caaccccacg
    19441 ttcgtcaccc gggagcacgg cctgtactac gccatggacg cagcagggat gcggatcgca
    19501 gccgatgctg tccgagccga tcctgaaggc gccgcgcgtc agcttgggct cgatggagag
    19561 tgacgcgctg accgcagcct gacctgcacg ctgcaatctt tcgtgcgggc aatcgagacc
    19621 tgaagcatcg catgaaagac ttcagcgccc agatcagaga cgtatcggct gcgatcttgg
    19681 tgctgtcctt cacggcggcg cagggcgagc ttggtagacc ttcccctgca ccggcacacc
    19741 cggcggggga cccttgaccg gcccaaaggg cagagtggcg agacgaccat tcggagaggg
    19801 acgacgtggg gtgggttcag acggcgagag aactgctgca ccaggggcca ttcgtggccc
    19861 tgtaccgaga ctcggtgctc cgcccggacg gcgctgctgg cacgtacgag cacgtcgtcg
    19921 tcgaggacgg cgtgcgcgtc gtcgctctcg atgacgacgg ccaggtcgtc ctggtcgagg
    19981 acgacttcta tctccaacag cgccgcgtcc tccacctccc cggcggcggc cgagggggac
    20041 aggacccaca ggcggccgcc atccgagaac tgggggagga gaccggcctt gtcgcgggcg
    20101 agatgcgtcc gctcggcgtt atcgaccccc tcccggcgac cacgggcgca aggacccatc
    20161 tcttcctggc cacggctctg cggctagggc ggacgcatcg cgacgagacc gagatcggaa
    20221 tgacggtgca gcggtggaag ttgacggccg ccgtcgaggc ggttcgagcc ggccggatca
    20281 ccgaagccgg gagtgtggct gcgttgttct tggcggaaca cgtggcacgt gcgtaggcgc
    20341 gcggtctacg ctgctggccg ctgccgcccg gtgatgtcgt gacccgtgaa gtcggccaac
    20401 tcggcttgga gacgcaccag atgcgcgttc agccgctcgg tccggcgccg ggccgtgttg
    20461 tacaacggcc aggcacgtac gcgggcaggg gcggggaact cccgatcgag gccaaggcca
    20521 gtctcgtcag cgtcaggccg cgcccgctca ccgcaatacg tgacccagtg ttcccggagc
    20581 aaggacagct ccaagacggc actgcgagcc tcgaacaccg ggaaggccag cgggtgattc
    20641 ggttcgaggg cggtgagtag atcgctcaag gcccggtcta catggatgct gtgctcgacg
    20701 gaggcgccga tgacgcggtc ctcgtcgtca ccgtccacgc cgttcgcact gaccggcgca
    20761 cggagagcga tcgtcacctg ggccttccac gccgcggcgc gtgcctccgc gccccggctt
    20821 cccgcgggcc ggagccttct gatccaggac accctcaccc tcaccctccg tcggtgtcgt
    20881 cgcacgtcac tctgccaccg cgcaaggacc agcaccaccg ggtcggggcg gtccggccga
    20941 aggataggaa atgccctggc ggactccggg ccatgcggag ccatcacgac ggccggagcc
    21001 gccgttgcgg agaccgctcg gcaagcacgc cgttggccac gagctgggac aagatcgtga
    21061 gacacgatgc cctggcccgg gaggctggcc cttgccgcgg ccgtctgcaa cttcagccac
    21121 gaaggacgac ttcttggcat ggaggtgtgt tcagagcgag ccgcttcgcc gcacgggcga
    21181 gggctgttgg ctgccggtgc ttctgtccag cacggtaggt cctcggtggc cggtcgctgc
    21241 tcgatggcgg acggacaaac gctgatcgcg ctacccgccg ctctgcttct tggccttggc
    21301 gtactccttg ccgctgcggc cgccgttggc gatgcgggcc acgctcgcgt acgtcaggtt
    21361 gagagctgcg gcctgttcgt cgtaggtcat ctgccctgag tccttgaggt ggttgacgtc
    21421 ctccgagcgg gcgtcgcgga gggccttctg caactcgggg atggcgttga gcacctcgcc
    21481 cagacgcttg gctcggtcga tggtgtgggg atcagcgaat agcggttcca gggcgctgaa
    21541 gatctcggga aggacgctgg tctgtggctt cgtctcggct gtcacgccac gcaatcttat
    21601 cgggtacccg atttgctgtc aatctcgcct ctcgtggctg ggtgcgtgaa catttnnnnn
    21661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnncgtgacc gaccccctgc
    22261 gatgtatcgg gtacccgatt gacagattat cgggtacccg atacactggc cctgtcgggc
    22321 caaccggaaa tctctgattt ccttcgaacc gaaagaggag cgcctcgatg gaaagcccca
    22381 acgctatggc catgatccat gccctccagc acatcctgaa caagtgcaac gaggaagccg
    22441 cgcgaagggg gcgccacacg tcggtcaatc cggatgttcg gctcgccctc ccttccaccc
    22501 actgccccgt ggagcaggtt ccgatcgtgc tcaaggggtc cggggactg
//
