LOCUS       NZ_LZNS01000001        21149 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2501919
            Orig. end                         :: 2523068
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21149
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="16"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21149
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21149
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11149](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11149
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(345..356)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.1"
                     /tool="antismash"
     misc_feature    410..424
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.96"
                     /tool="antismash"
     misc_feature    478..493
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    complement(1427..1440)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            1441..3114
                     /locus_tag="STBA_RS10920"
                     /old_locus_tag="STBA_22100"
     CDS             1441..3114
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091373.1"
                     /locus_tag="STBA_RS10920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22100"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_077063245.1"
                     /transl_table=11
                     /translation="MLRDYRAAFQIAQFPMALVGAAGQILAANAALGLLLGVEPERLAG
                     VRADAVAGLGLDGRTRGSYHAVLRGHSDRLRCTRRLKHADGHSLWAEVTVLPTPTEDSA
                     ALLTVLDISERRDLQERLRHIQMHDPVTLLPNRALFFERLATAVSDSATGRIGLCFLDL
                     DGFKAVNDTLGYRVGDELLGAAAQRLAECATGAGGHLVARLGGDEFAVLVEGSSGTKQL
                     TDLAETMLTALQRPFDLAGQRLAVSASIGVVERESATTTATGLMQAASTTLYWAKADGK
                     ARWTLFDPERNAHRMTRQSLSSTLRRGVDRGEFTLEYQPIVGLADDIVRGAEALVRWRH
                     PQFGTLGPDRFIGLAEENGAIVPLGRWVLGEACRQARRWQVEHQGPPLFVSVNVAVRQV
                     WDSDLVSDVAEALRVSGLPSGLLQLELTESAVMGSAGRPLQALQALSDMGVRIAIDDFG
                     TGYSNLAYLSRLPVRALKLDGMFVRGFRTARHLNPADETIVSSLVQLAHKLGLTVTAEC
                     VEGPAQAERLRRIGCDTGQGWHYARPMPPDHLATLLAGRD"
     gene            3195..3548
                     /locus_tag="STBA_RS10925"
                     /old_locus_tag="STBA_22110"
     CDS             3195..3548
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS10925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_22110"
                     /product="hypothetical protein"
                     /protein_id="WP_143659469.1"
                     /transl_table=11
                     /translation="MAEFIPLDRFLRLLADESVPVVHRALWALLWESDVRVLDLLALDV
                     SAEPRIRPPADGDLGGLAAALLGRLAGDRTSGPLFAVGPRALSWDEAVRTAQAGGVAIH
                     AIRTSGRQHRGRR"
     gene            complement(3665..4396)
                     /locus_tag="STBA_RS10930"
                     /old_locus_tag="STBA_22120"
     CDS             complement(3665..4396)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091371.1"
                     /locus_tag="STBA_RS10930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22120"
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="WP_077059065.1"
                     /transl_table=11
                     /translation="MAATVGFLYPGFSAEDDFPRMEALLNDAGADVRLPLVHTDIGTDA
                     HRVDALLEMGSVDRLTAKLDEIAAHGAEAVVWACTSASFVFGPDGAAEQVRRLAAHAGR
                     PASSTSFAFARAAQAIGVERVAVAATYPDDVAALFADFLKAAGIEVVGVRGSGIITAAE
                     VGTWGREEVLRLLREGDDPAADAVLLPDTALHTAAWLPDLEAAAGKPVLTANQVTAWEG
                     LRLLGRTAACPALGSLFTRAA"
     gene            complement(4404..5234)
                     /locus_tag="STBA_RS10935"
                     /old_locus_tag="STBA_22130"
     CDS             complement(4404..5234)
                     /GO_function="GO:0036361 - racemase activity, acting on
                     amino acids and derivatives [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605417.1"
                     /locus_tag="STBA_RS10935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22130"
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="WP_077059066.1"
                     /transl_table=11
                     /translation="MDVSFLGGPLPQRGIGVVAPFDFALDRELWRWVPDDVSLHLTRTP
                     FVPVEVSLHLARLVSEHETLREAVRALSAVSPEVVAYACTSGSFVGGVAGERAMSAAMR
                     QSGELPALTTSGALLAALDELGARRIAVVTPYTRSVTDSLEEYLREAGVEVSGRSYLGL
                     TREIWRVPYRDVVDMARDAVADAPDALFISCTNLPTYDVIPQLEAELRMPVVSANQVTM
                     WSALRSIGKAAVGPYQALLDPVARRGPASMAPDAGSPEVALAAEPPPVFPDEEV"
     misc_feature    complement(5279..5288)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 12.92"
                     /tool="antismash"
     gene            5385..6353
                     /locus_tag="STBA_RS10940"
                     /old_locus_tag="STBA_22140"
     CDS             5385..6353
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574268.1"
                     /locus_tag="STBA_RS10940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22140"
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="WP_077059067.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 4.4e-46, bitscore:
                     155.1, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEACVLVLDADPLPRLERLTGRAVVRHSDEQSLARLLPDADVLL
                     VWDFTSDAVREAWPGPGARPRWVHTASAGVDRLLCPELLASDTVLTNARGVFDRPIAEY
                     VAGLVLAMAKDFRHSWNVQRERRWQHRETEKVFGSRAVVVGSGPIGRRIGTTLQALGVT
                     VDLVGRTARGADADFGRVHAGGDLPALLPTADWVVCAAPLTPQTEGMFDAAAFALMKPT
                     ARFLNVGRGGHVVENDLVAALRAGRPAGAALDVFAAEPLPADSPLWDLPELIVSPHMSG
                     DTYGWRDDLADQFQDNFDRWLAGEPLANVVDKRLGYVPAEG"
     gene            6353..7837
                     /locus_tag="STBA_RS10945"
                     /old_locus_tag="STBA_22150"
     CDS             6353..7837
                     /EC_number="3.5.1.4"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542219.1"
                     /locus_tag="STBA_RS10945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22150"
                     /product="amidase"
                     /protein_id="WP_079251848.1"
                     /transl_table=11
                     /translation="MTDLCSLTAVELTARYASGDLSPVAVTKATLARAEAVQPAVNAFV
                     FTDAEGALAQAAAAEERWGRGAPAGPVDGVPVTVKDILLQRGHPTRRGSAALPAGAGPW
                     AEDAPAVARLRESGAVFLGKTTTPEFGWKGVTDAPLSGATGNPYAPERTAGGSSGGSAA
                     AVALGAGPLSLGTDGGGSVRIPASFCGIFALKPTYGRVPLYPASAFGTLAHVGPMTSDA
                     ADAALLLDVIARPDPRDWSQLAPPARPFRQALTAGEGGLAGLRVAWSPTLGGVVVAPDV
                     AAAVRGAVERLAGLGAEVTETDPPLPPLPEVLAAFHTLWFSGAARVTQHFDEAQRAAMD
                     PGLREIVAQGAGYGALDYLAAVDVRMAMGRLMGTFHEEYDLLLTPTLPITAFGAGTEVP
                     EGSGLARWTEWTPFTYPFNMTQQPAASVPCGTGADGLPVGLQLVGARHADALVLRAAHA
                     LYAAGVAGIPAPALGAPATGTPATVDLATGAPGRGR"
     gene            complement(7869..8378)
                     /locus_tag="STBA_RS10950"
                     /old_locus_tag="STBA_22160"
     CDS             complement(7869..8378)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060960.1"
                     /locus_tag="STBA_RS10950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22160"
                     /product="DUF3830 family protein"
                     /protein_id="WP_077059068.1"
                     /transl_table=11
                     /translation="MTNADDRFITVSLDKREVSCTARLLSDRAPITCDAVWNALPLGGD
                     VYHAKYARNEIYALVPPFAPQEPPLENPTITPIPGDLCYFTFTQTQLGTSSYGYETDAK
                     HQGRTTVVDLALFYERNNLLINGDAGWVPGIVWGAVVDGLDRMADACQDLWRAGALGET
                     LSFRRA"
     gene            complement(8375..9796)
                     /locus_tag="STBA_RS10955"
                     /old_locus_tag="STBA_22170"
     CDS             complement(8375..9796)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354204.1"
                     /locus_tag="STBA_RS10955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22170"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_253194642.1"
                     /transl_table=11
                     /translation="MSLNSIMGYPSVDDLVHVAHGMARRHPKAIRLRRLGSSRAGDPLL
                     LLTVGHGARNVLLVAGAHANEPVGGATSLRLAELLLGGSGGTIGTAAGGGLLEDSDCSW
                     HFLLCLDPDGSRLNGDWLHGLPGVREYFHGFYRPLFASQPEFLPAPGEKRRPLPESEIL
                     LALLDELRPEFQFTLHGSEMGGAFVQATRAVPGLVDAVREVSAALSIPVDLRPFDGIDW
                     HVSGPGVLVLPEPDTVRERDPSGLITGTTWLYPARYGTVTVILEAPAWAVEAVADPAPY
                     PDPEKAIAEAGENLLQRIGQVAGLLALADEWNGAVNDPFLPAVRELVAVSPGVVETWLK
                     PGFRYADGTRPAATRGSAAALLIAARRIALRAAAMLDRSLRAAPGPGAAKARLGLDDLV
                     TEWCREFEAEFAPRAVPVRDQAELQARLALHCVARVLGPRVLGPPPADRQEPTRRRPAA
                     WHRGHPARPPLEGTS"
     misc_feature    complement(9701..9703)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..11149
                     /locus_tag="STBA_RS10960"
                     /old_locus_tag="STBA_22180"
     CDS             10001..11149
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116435.1"
                     /locus_tag="STBA_RS10960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22180"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_253194644.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 2.8e-19,
                     bitscore: 67.7, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.3e-41, bitscore: 141.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVEALWKPRIKPEHAAYRTTEGNIRIGSVIFGIGAEIKDPAGWL
                     WTLASGADGTRTEEALIGHVLAGHPELPELTEDEVGDALRQLNEAGFVEDAAAERPAAL
                     SEREAERYSRGVPLLRWMDLSPRRNAWEAQARLKESAVLLIGLGGVGGMAAQALVASGV
                     GRLHCVDSDRVELSNLNRQTLYREADLGSGKVAAGVAHLQALNSDVRVTGQETRVGTPG
                     ELAALLSRPPAGAGAWDALLLCADQPSDIRRWTNLTCLTARVPWVDGGYRGPLITVGVY
                     RPGRGGCYECLRTAEYARRDLRLAPGQDESRAAPRMAWNPVNAVTAGVAGSLMAHAVLT
                     LLTGIPPTEPGFRFGVNLMALDDATYTRDPARPDCPACGTGR"
     misc_feature    10016..10018
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        10022..10300
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_STBA_RS10960_Pantocin_Microcin_RRE.1"
                     /evalue="1.10E-21"
                     /identifier="RREFam017.1"
                     /label="STBA_RS10960"
                     /locus_tag="STBA_RS10960"
                     /protein_end="100"
                     /protein_start="7"
                     /score="67.7"
                     /tool="antismash"
                     /translation="KPRIKPEHAAYRTTEGNIRIGSVIFGIGAEIKDPAGWLWTLASGA
                     DGTRTEEALIGHVLAGHPELPELTEDEVGDALRQLNEAGFVEDAAAER"
     gene            complement(11637..12479)
                     /locus_tag="STBA_RS10965"
                     /old_locus_tag="STBA_22190"
     CDS             complement(11637..12479)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016435038.1"
                     /locus_tag="STBA_RS10965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22190"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_253194646.1"
                     /transl_table=11
                     /translation="MTDLTGFSINQMTAKQLPLPELVNGLVGLGVPGVGLWREPVARYG
                     LAAAAALVADAGLSVTTLCRGGFLTAIDPAERAAALADNRAAVDEAAALGTDTLVLVSG
                     GLPAGSRDLAGARERIADALAELGPYAAERGVRLAIEPLHPMYAADRCVVSTLEQALDL
                     AERFPAEQVGIVVDTYHLWWDDRVAAQIRRAGAGGRIHSFQLADWVTPLPAGVLNGRGQ
                     IGDGAVDMRWFRDAVAEAGYRGPVEVEIFNDGLWARDGQEVLAETVARYRECLVSDAA"
     gene            complement(12476..13630)
                     /locus_tag="STBA_RS10970"
                     /old_locus_tag="STBA_22200"
     CDS             complement(12476..13630)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435703.1"
                     /locus_tag="STBA_RS10970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22200"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_077063247.1"
                     /transl_table=11
                     /translation="MIRLPEPGGQLREYRPRAVPASPAPGGAPLTSRIVFSAAHVVADP
                     FADTTPEGPAAVDWDTTLAFRRHLWAHGLGVAEAMDTAQRGMGLDWAGAAELIRRSGAE
                     ARAAGGRIACGVGTDQLTGPADTAAVRAAYEEQLAVVEETGAQAILMASRALAAAARGP
                     EDYAEVYGHLLRQAAEPVVLHWLGPMFDPALTGYWGSEDLDAATDTFLDIIGTHADKVD
                     GVKVSLLDAQREIKLRRRLPSGVRCYTGDDFNYPELIAGDEQGFSHALLGIFDPLGPLA
                     AEAVRTLDTGDVAGFRAHLDPTVELSRHLFRAPTRYYKTGVVLLAWLAGHQDHFTMVGG
                     LQSARSLPHLARAYELADGLGLFPDPALARERMARLLAVHGVAQ"
     misc_feature    13624..13638
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            complement(13713..14876)
                     /locus_tag="STBA_RS10975"
                     /old_locus_tag="STBA_22210"
     CDS             complement(13713..14876)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006135388.1"
                     /locus_tag="STBA_RS10975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22210"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_077059070.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 4e-08, bitscore:
                     32.6, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 3.2e-25,
                     bitscore: 87.2, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKTVRIAMNGVTGRMGYRQHLVRSILAIREQGGVDLGDGSVI
                     WPEPVLVGRREHALREIARRHGLDPEAAVTTDLDAVLADDGIDIYFDSQITLTREAAIK
                     QAIAAGKHIYTEKPTATSLEGALALARQAADAGVKHGVVQDKLFLPGLQKLKRLVDGGF
                     FGRILSVRGEFGYWVFEGDWQPAQRPSWNYRSEEGGGIVVDMFPHWEYVLHELFGRVET
                     VQALAATHIPQRWNEQGKPYEATADDAAYGIFQLAGGIIAQINSSWSVRVNRDELVEFQ
                     VDGTEGSAVAGLRNCRAQHRSATPKPVWNPDLPATEVFREQWQEVPDNGEFDNGFKAQW
                     ELFLRHVVLDEPYTWDLLAGARGVQLAELGLASSADGRRLTVPELSL"
     misc_feature    complement(14900..14911)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.34"
                     /tool="antismash"
     gene            14966..16012
                     /locus_tag="STBA_RS10980"
                     /old_locus_tag="STBA_22220"
     CDS             14966..16012
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007493866.1"
                     /locus_tag="STBA_RS10980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22220"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_077059071.1"
                     /transl_table=11
                     /translation="MSVTLADVAARAGVSAATVSRVLNGNYPVAGATRNRVLRAVEELE
                     YVVNGPASALAAATSDLVGVLVNDIADPFFGIMAGAVQSEIGHATRKLAIVCNTGGSPE
                     RELTYLTLLQRQRAAAVVLTGGAVEDPAHGEALAARLRRLDAAGSQVVLCGRPPLGAAT
                     AGPHPLTVTFDNRGGARRLTDHLLTLGHRRLGYLAGPAARTTTRHRLEGHRTAMAAAGL
                     ADDAERLTAHGAYDRASGYDGALELLRRDPDLTAILAANDTVALGVCAALRDRGLRIPQ
                     DVSVTGFDDLPFAVDAMPALTTVRLPLHAAGARAGRLALGREDAPPGGVATFRGDLMVR
                     DSTAPPRR"
     gene            complement(16473..17024)
                     /locus_tag="STBA_RS10985"
                     /old_locus_tag="STBA_22230"
     CDS             complement(16473..17024)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105244.1"
                     /locus_tag="STBA_RS10985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22230"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_077059072.1"
                     /transl_table=11
                     /translation="MSTVIVRLSAPEELLAHAEELAALLADVVADGASLGFVRPFGRAD
                     AAAWWAARAPALADGGLTVWAARSGGRLVGTVSLALAPEQNGRHRGHIAKLMVHPGARG
                     RGTAAALLATAERAATAAGVTLLLLDTETGSTAEHLYRSAGWTKYGEVPDYASDPAGTL
                     QPASFFHKFLSRTETLRTTA"
     gene            complement(17021..17623)
                     /locus_tag="STBA_RS10990"
                     /old_locus_tag="STBA_22240"
     CDS             complement(17021..17623)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431309.1"
                     /locus_tag="STBA_RS10990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22240"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_077059073.1"
                     /transl_table=11
                     /translation="MLPDVGSTEVAAGPPDGSVDARLAARLGELRGERGWSLEELAERS
                     GVSRSTLSRVERAELSPTAAMLGKLCTVYERTMSRLLSEVEREPPGLVRAGRQEVWADA
                     SAGFVRRSVSPPHAGLRAEVIEGELRPGAAIAYDAPPVPGLEHHVWVLDGAVEVTVGEE
                     THGLRRGDCVRFRLWGPSRYHCPGPAAVRYAVVVVLP"
     gene            17665..18219
                     /locus_tag="STBA_RS10995"
                     /old_locus_tag="STBA_22250"
     CDS             17665..18219
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471060.1"
                     /locus_tag="STBA_RS10995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22250"
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_077059074.1"
                     /sec_met_domain="Mac (E-value: 5.6e-14, bitscore: 50.8,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQKERMLAGELYIADDPEIAADALRAVQLSERFNATATADPET
                     RRAALAALLGEVGEGTEVRPPFHVDYGHHITIGPRTFVNFGAVFLDVAPITIGADVQIG
                     PNVQLLTPTHPVEPEPRREKWEAAAPITIGDNVWLGGGVIVCPGVTIGENTVVGAGAVV
                     TKDLPPGVVAVGNPARVTRGV"
     misc_feature    complement(17679..17692)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.03"
                     /tool="antismash"
     gene            18311..20503
                     /locus_tag="STBA_RS11000"
                     /old_locus_tag="STBA_22260"
     CDS             18311..20503
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181003.1"
                     /locus_tag="STBA_RS11000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22260"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_253194648.1"
                     /transl_table=11
                     /translation="MTSLRRGGKGGAFTLLLVYLALLTALQIWSGHNNLTGWSAYSVLA
                     PMAASALLTMRATLVVGLLTIVSVIIAYGGSIPGLSSGTRGVIVSSAACSTVLAMVICR
                     IRLNREARVSRLTIARERLTLLRVASRHVGSTLDVRRTACEVTEIAVPGFADLVTVDLY
                     ESVLRGEEPAAPDGNPLRRVAQRSVADEESADEGARDGANGPDGPDGPDGPDGPDGQQE
                     QQEQQQQQEEQERTDEKEAYEGGTPALGHHLTQGPDVRARILDDSDVGTWLAANPRYAA
                     QATAGTSRSGIAVPLRARGTTLGVAVFVRHLRADPFDADDLLLAEEIGAQAAVCVDNAR
                     RYTHEHRASLTLQQSLLPRRLPEVAAVEVATRYLPADSSAGVGGDWFDVIQLSGARVAL
                     VVGDVVGHGLYASATMGRLRSAVRTLADIDLAPDELLTHLDDVVIRLRLETEGGEQEGG
                     AQENPAGAVGATCLYAVYDPVSRTCSMARAGHPAPALVRPDGRVEFIDAPPGQPLGLGG
                     LPFEAHEVLLPEGSYLALYTNGLIARHHDMERGQATLRQALSQPVHSPEAACDAVLRAM
                     LDGEPTDDIALLVARTRALDAAHVASWHIPDDPTAVAHARELAEGQLTSWGLEEATFTM
                     ELVVSELVTNAIRHADGPIQLRLIREPAALICEVSDNSSTSPHLRRARVFDESGRGLFI
                     VAHLTARWGTRHGREGKTIWAELSSSPSPEGLLAAG"
     gene            20555..21034
                     /locus_tag="STBA_RS11005"
                     /old_locus_tag="STBA_22270"
     CDS             20555..21034
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019548399.1"
                     /locus_tag="STBA_RS11005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_22270"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_077059075.1"
                     /transl_table=11
                     /translation="MTESAAPLATGPLGMRLLAFDRLPEDTRFDREPAGYALVALWHAG
                     LLLLVHERDRDCWELPGGTLDPGETPREAAARELAEESGQHVAPERLHFAGFARTWLPD
                     RPVLRGALFHAEADERAVFEPTPEIAGVHWWNLRDPMPHGRLQTVDAYLAALVRP"
ORIGIN
        1 ggcccttcgg ccgaggcgac gtcgctgcgc acccggtaga gcagtacgcc ccgcgtgcac
       61 gtggtggtgt cgttgcccac gggggcgcgc gcctcggcca cgagcgcctc ctgcggtccg
      121 gtgcggacca cggcgagccg ggtgtccgat tcggggttgc ccttctccag gggcgcaccg
      181 aggggctgga gggtgtgcag cgtggtgccg gccccgcgca cgcagtcgac gtgccccggg
      241 ccgagccacc cgagtttcca cttgtgccag ccgaagagtt cgggggccag gccgaactgg
      301 ctgcccatga gatcccagtc gccgacgtgg gtgtcccagt cgccgaaacc gttctccggc
      361 cggttgtaga ggtcgggcag gtcgaagacg tgcccggtct cgtgggcgag gacattgcgg
      421 tccgggcggc gctgctcgaa caccgtgacg agacggcgga cctccgcgtc gccgacggtg
      481 accggcttgt cgaagttgac gaccttggtg gcgtccgggt ccacgccggg cgcgtccgga
      541 tcggcgacca ggtagacgat gtcgtaggcg gcgaggtcga cgcgcccgga gaccacctcg
      601 atcgcgtcct cgatgtacgc ggagcgcccg gcgggcgccc agtcgcgctg tatgccgtag
      661 tccgccgagg cgtcgggcat cggcagccag tcgtccacca cttcggtctc caggtccagc
      721 ttcccgtagg aggcggtgcg gaagtagtcg ctggtggccg ggaagtagtc ctcggcgatg
      781 cggtcggggc gcagccgcgg ggtggcgtcg gggaacgcga ggaagagcat gacggccttc
      841 agcgtgccca gggggcgggg gtaggcgtcg ttccaggtgt cgacgccctc ggagtggtgg
      901 atggccgaac gcggcaggct gcacggctcg tcggccatgg ccgcggtgcc gggacccgcg
      961 gtcagcgtcg tccccaggag ggcggtcagc gcggcgagca cggccgcggg acgtcggtga
     1021 gcacggcgca cgacgacctc cgatcgggcc ttatgggaac accgccacca ctctgttcag
     1081 atttcccatg ttttgccctg tttcgatagc ccgcccgggt cacggagata cgattaccct
     1141 gcgtgcactt cagtcgggaa cgatccggag ggcacacccg tcgagcagaa acgatcagct
     1201 agtcgaaagc ttgtcggaag cacaggtttc gggttgcgaa acagccgctg cgggcactgg
     1261 ctccatccgc gccccagcct ctatgatcgc cacatttcca gcgcggatac gccaagcggg
     1321 cagccgggga gcgcccgaca gcaccatcgg gagcgatcgg tgaacggacc ccacacagca
     1381 ccgggccacg accccggaag gccccacgaa gcgagcccat cagcccttac ggaaagtgac
     1441 atcctgcggg actaccgggc cgctttccag atcgcccagt tccccatggc gctggtcggc
     1501 gccgccggcc agatcctcgc cgccaacgcc gcgttgggac tgctgctcgg cgtcgagccg
     1561 gagcgcctgg cgggcgtccg cgccgacgcc gtcgccggcc tcggcctcga cgggcgcacc
     1621 cgcggctcct accacgcggt gctgcgcggc cacagcgacc gcctgcgctg cacccggcgc
     1681 ctgaagcacg ccgacgggca cagcctgtgg gccgaggtca ccgtcctgcc cacgcccacc
     1741 gaggactccg ccgcgctgct gaccgtgctc gacatcagcg aacgccgcga tctacaggag
     1801 cggctgcggc acattcagat gcacgacccc gtcaccctcc tgccgaaccg tgcccttttc
     1861 ttcgaacggc tggccaccgc cgtgtccgac tccgcgaccg gccggatcgg gctgtgcttc
     1921 ctggacctcg acggcttcaa ggccgtcaac gacacgctcg ggtaccgcgt cggggacgag
     1981 ctgctcggcg ccgccgccca gcgcctcgcc gaatgcgcca ccggcgccgg cggccacctg
     2041 gtggcgcggc tcggcggcga cgagttcgcc gtcctggtcg aggggtcgag cggcacgaag
     2101 cagctgacgg acctggccga gaccatgctc accgcgctcc agcgcccgtt cgacctggcc
     2161 gggcagcggc tcgccgtctc ggccagcatc ggcgtcgtcg agcgggagtc ggcgaccacg
     2221 acggccacgg ggctgatgca ggccgcgagc accacgctgt actgggccaa ggccgacggc
     2281 aaggcccgct ggacgctgtt cgaccccgag cgcaacgcgc accgcatgac ccgccagtcg
     2341 ctgtcctcca ccctgcggcg gggggtggac cgcggcgagt tcaccctgga gtaccagccg
     2401 atcgtcgggc tggccgacga catcgtgcgc ggcgcggagg cgctggtgcg ctggcgccac
     2461 ccgcagttcg gcacgctcgg ccccgaccgg ttcatcggcc tcgccgagga gaacggggcg
     2521 atcgtgccgc tcggccgctg ggtgctcggc gaggcgtgcc gccaggcccg ccgctggcag
     2581 gtcgagcacc agggcccgcc gctgttcgtc agcgtcaatg tggcggtccg ccaggtctgg
     2641 gactccgacc tggtcagcga tgtcgcggag gcgctgcgcg tatcgggcct gccgtccggg
     2701 ctgctccagc tggagctgac cgagtccgcc gtcatgggct ccgcgggccg ccccctacag
     2761 gctttgcagg cgctgtccga catgggcgtg cgcatcgcga tcgacgactt cggcaccggc
     2821 tactccaacc tggcctacct cagccgcctc ccggtgcgcg ccctgaagct ggacggcatg
     2881 ttcgtccgcg gcttccgcac cgcccgccac ctcaacccgg ccgacgagac catcgtcagc
     2941 tccctggtcc agctcgccca caagctcggc ctgaccgtca ccgccgagtg cgtcgaaggg
     3001 cccgcccagg ccgagcggct gcgccgcatc ggctgtgaca ccggccaggg ctggcactac
     3061 gcgcggccca tgccacccga ccacctcgcc acgctgctcg cgggccgcga ctgaggcgga
     3121 gcacaccgcg gtcggcgtgc cgcggacctg tacgggggga ggcggcggag gaatactccc
     3181 gagccatggc gatcatggct gaattcatcc ccctcgaccg cttcctgcgg ctcctcgccg
     3241 acgagtccgt tcccgtggtg caccgcgccc tgtgggcgct gctgtgggaa agcgacgtgc
     3301 gggtgctcga tctgctcgcg ctcgacgtat cggcggagcc ccgcataaga cccccggccg
     3361 acggcgacct cggcgggctg gccgccgcgc tgctgggccg gctggccggg gaccgcacct
     3421 cggggccgct gttcgcggtg ggcccgaggg ccctttcctg ggacgaggcg gtgcgcacgg
     3481 cgcaggccgg cggcgtggcc atccatgcca tccgcaccag cggcaggcag caccgcggcc
     3541 ggcgctgacc ccgtcggccg ggggcgcggg gccgggtccg cgcgccgcgg gccccggccg
     3601 gagagccggg gcccgcgggg tgtgcgcggt ggtgcgcggg tacgcagggg cgcgcaggaa
     3661 cgagctacgc ggcgcgcgtg aagaggctgc cgagcgccgg gcaggccgcg gtgcggccca
     3721 gcaggcgcag cccctcccag gcggtcacct ggttggccgt cagcaccggc ttgcccgccg
     3781 cggcctccag gtcgggcagc caggccgccg tgtggagcgc cgtgtccggc agcagcaccg
     3841 cgtccgccgc cgggtcgtcg ccctcgcgca gcagccgcag cacctcctcc cggccccacg
     3901 tgcccacctc ggcggccgtg atgatgccgc tgccccgcac gccgacgacc tcgatgcccg
     3961 cggccttcag gaagtccgcg aacagcgccg ccacatcgtc cggataggtc gccgcgacgg
     4021 ccacccgttc cacgccgatg gcctgcgccg ctcgggcgaa ggcgaacgac gtgctggacg
     4081 ccggccgccc ggcgtgcgcc gccaggcggc gcacctgctc cgcagcgccg tcgggtccga
     4141 agacgaaact ggcgctggtg caggcccaca ccacggcctc ggcgccgtgc gcggcgatct
     4201 cgtccagctt tgccgtcagc cggtcgaccg agcccatctc gagcagcgcg tccacccggt
     4261 gggcgtccgt gccgatatcg gtgtgtacga gcgggagccg gacgtccgcc cccgcgtcgt
     4321 tcagcagcgc ctccatgcgg gggaagtcgt cctccgcgga gaagcccggg taaaggaaac
     4381 caaccgtcgc ggccatacgg atctcacact tcctcgtcgg ggaacaccgg cggcggctcg
     4441 gcggcgagcg ccacctctgg gctgcccgcg tccggtgcca tggacgcggg gccgcgtctg
     4501 gccaccgggt cgagcagggc ctggtacggg ccgacggccg ccttgcctat ggaccgtagc
     4561 gcggaccaca tggtgacctg gttcgccgag acgacgggca tccgcagttc cgcctccagc
     4621 tgcgggatga cgtcgtaggt gggcaggttg gtacagctga tgaacagggc gtccggtgcg
     4681 tccgccacgg cgtcccgcgc catgtcgacc acgtcccggt acggcacccg ccagatctcc
     4741 ctggtcagcc ccagataact gcgtccgctg acctcgacgc ccgcctcgcg gagatactcc
     4801 tccagcgagt cggtcaccga cctggtgtac ggcgtgacca cggcgatccg ccgcgcgccc
     4861 agttcgtcga gcgcggcgag cagtgcgccc gacgtggtca gcgccggcag ctcaccggac
     4921 tgccgcatgg cggcgctcat ggcccgttcg ccggcgacac cgccgacgaa actccccgag
     4981 gtgcaggcgt aggccaccac ctcgggactg accgccgaca gggcgcggac cgcttcgcgc
     5041 agtgtctcgt gctcgctgac cagccgcgcc aggtggaggc tgacctccac cgggacgaac
     5101 ggcgtccgtg tcaggtgcaa cgagacgtca tcgggcaccc accgccagag ctcacggtcg
     5161 agcgcgaaat cgaatggtgc gacgactccg atgccccgct gcgggagcgg gccacccaga
     5221 aaggagacat ccatgtcgaa ccccgcttca tacgggccgg gaataccggg aagagacttg
     5281 aaaaagcaga tgccttcgtt gacgaaggta gagacgggtt cctaccgtgg tcaatccttg
     5341 acttccagcc aaacaccccc tcgttgcgga gcggtttccc tgccatgtcc gaagcctgcg
     5401 ttctcgtcct cgacgccgac cccctgcccc gcctcgaacg gctgacgggc cgcgccgtgg
     5461 tacggcacag cgacgagcag tcgctggccc gcctgctgcc cgacgccgac gtgctgctcg
     5521 tgtgggactt cacctcggac gccgtgcgcg aggcgtggcc cgggccgggt gcccggccgc
     5581 gctgggttca cactgcgagc gcgggggtcg accggctgct gtgccccgag ctgctggcgt
     5641 ccgacacggt gctgacgaac gcccgcgggg tgttcgaccg gccgatcgcc gagtacgtgg
     5701 cggggctcgt gctggccatg gccaaggatt tccggcacag ctggaacgtc cagcgcgagc
     5761 gccgctggca gcaccgcgag accgaaaagg tgttcggcag cagggccgtc gtcgtcggct
     5821 cgggaccgat cgggcggcgc atcggcacca cgttgcaggc actcggcgtg acggtggacc
     5881 tggtcgggcg caccgcccgc ggggccgatg cggacttcgg ccgcgtccac gcgggcgggg
     5941 acctgcccgc gctgctgccg acggcggact gggtggtctg cgcggctccg ctgaccccac
     6001 agaccgaagg catgttcgac gcggcggcct tcgcgctcat gaagcccacg gcccggttcc
     6061 tgaacgtcgg gcgcggcggg cacgtcgtcg agaacgacct cgtcgcggcg ctgcgcgccg
     6121 ggcggcccgc gggggccgcg ctggacgtgt tcgccgccga gccgctgccc gcggacagcc
     6181 cgttgtggga tcttccggaa ctgatcgtgt cgccgcacat gtccggcgac acttatggct
     6241 ggcgtgacga ccttgccgac cagttccagg acaacttcga ccgctggctt gcgggtgaac
     6301 cgctggccaa cgtcgtggac aagcgccttg gctacgtgcc cgcggagggc tgatgaccga
     6361 tctctgctcc ctgaccgccg tcgaactgac cgcccggtac gcgtccgggg acctctcccc
     6421 ggtggccgtg acgaaggcca cgctggcgag agccgaggcc gtgcagccgg ccgtcaacgc
     6481 cttcgtgttc accgacgcgg agggcgccct ggcgcaggcg gcggccgccg aggaacgctg
     6541 ggggcgcggc gcacccgcgg gccccgtgga cggcgtgccc gtgaccgtca aggacatcct
     6601 gctccagcgc ggccacccca cgcggcgcgg ctccgccgcc ctgcccgcgg gcgcgggccc
     6661 gtgggcggag gacgcgcccg cggtcgcgcg gctgcgcgag tcgggtgcgg tgttcctcgg
     6721 aaagaccacc acgccggaat tcggctggaa aggagtcacg gacgcgccgc tctccggcgc
     6781 gaccggcaat ccgtacgcgc cggagcgcac cgccggcggt tcgagcggcg ggagcgccgc
     6841 ggcggtcgcg ctgggcgcgg gaccactgag cctgggcacg gacggcggcg ggtcggtccg
     6901 gatcccggcc tcgttctgcg ggatcttcgc actgaagccc acctacggcc gggtgccgct
     6961 gtacccggcg agcgcgttcg gcacgctggc ccacgtcggc ccgatgactt cggatgccgc
     7021 ggacgcggcg ctgctgctcg acgtcatcgc ccggcccgac ccgcgggact ggtcccaact
     7081 ggcgccaccc gcccgcccgt tccgccaggc gctgacggcc ggcgagggcg gtctcgccgg
     7141 gctgcgcgtc gcctggtcgc ccacgctcgg cggggtggtc gtggcgccgg acgtggctgc
     7201 cgcggtgcgc ggggcggtgg agcgcctggc cgggctcggc gccgaggtga cggagaccga
     7261 cccgccgctg ccgccgctgc ccgaggtgct cgccgcgttc cacaccctgt ggttcagcgg
     7321 cgcggcgcgg gtcacccagc acttcgacga ggcgcagcgg gcggcgatgg acccgggcct
     7381 gcgggagatc gtggcgcagg gcgccgggta cggggcactg gactacctgg cggcggtcga
     7441 cgtgcggatg gcgatgggcc gcctgatggg cacgttccac gaggagtacg acctgctgct
     7501 cacgccgacc ctgccgatca cggcgttcgg cgccgggacg gaggtgcccg agggctcggg
     7561 gctggcgcgg tggacggagt ggacgccgtt cacctacccg ttcaacatga cccagcagcc
     7621 cgcggcttcc gtgccctgcg ggaccggcgc ggacgggctg ccggtcggcc tccagctcgt
     7681 gggcgcgcgg catgcggacg cgctggtgct gcgcgccgcg cacgccctgt acgcggccgg
     7741 cgtggccggg atccccgcgc ccgcgctcgg ggcgcccgcg accgggacgc ccgcgaccgt
     7801 ggatctcgcg accggggcgc ccgggcgcgg gcgctgagcg cgtcccgggt ccggtcggac
     7861 cccgggccct acgcccggcg gaaggagagg gtttcgccga gggccccggc ccgccacagg
     7921 tcctggcagg cgtcggccat ccggtcgaga ccgtcgacca ccgcgcccca gacgatgccg
     7981 gggacccagc ccgcgtcgcc gttgatgagc aggttgttcc gctcgtagaa cagcgccagg
     8041 tccacgacgg tcgtccggcc ctggtgcttg gcgtcggtct cgtagccgta ggagctggtg
     8101 cccaactggg tctgggtgaa cgtgaagtag cacaggtcgc cggggatcgg ggtgatcgtc
     8161 gggttctcca gggggggctc ctggggcgcg aagggcggga ccagggcgta gatctcgttg
     8221 cgcgcgtact tcgcgtggta cacgtcgccg ccgagcggca gcgcgttcca cacggcgtcg
     8281 caggtgatcg gcgcccggtc gctcagcagc cgggccgtac agctgacctc gcgcttgtcg
     8341 agcgagacgg tgatgaaccg gtcgtcggcg ttcgtcatga ggttccctcc agtggtgggc
     8401 gggccggatg cccacgatgc cacgccgccg gccggcggcg ggtcggctcc tggcggtccg
     8461 cgggcggcgg gccgagcacc cgcgggccga gcacccgcgc gacgcagtgc agcgccaggc
     8521 gtgcctggag ctcggcctgg tcacggaccg gaacggcgcg cggcgcgaac tccgcctcga
     8581 actcccggca ccactccgtc accagatcgt cgagcccgag gcgcgccttc gcggcgccgg
     8641 ggcccggcgc ggcgcgcagc gaacggtcca gcatcgccgc ggcgcgcagc gcgatgcgac
     8701 gggcggcgat cagcagggcg gcggcgctgc cgcgggtggc ggcggggcgg gtgccgtcgg
     8761 cgtaccggaa gcccggcttc agccaggtct cgaccacgcc gggcgaaacg gcgacgagtt
     8821 cgcggacggc gggcaggaac gggtcgttca cggcgccgtt ccactcgtcg gcaagggcca
     8881 gcagaccggc gacctggccg atgcgctgga gcagattctc gccggcctcg gcgatggcct
     8941 tctccgggtc ggggtagggc gcggggtcgg cgacggcctc gaccgcccag gccggtgcct
     9001 ccaggatcac ggtgaccgtg ccgtaccgcg ccgggtacag ccacgtcgtg ccggtgatca
     9061 gccccgaggg gtcgcgctcg cgcacggtgt ccggctcggg gagcaccagg acgccggggc
     9121 ccgacacatg ccagtcgatc ccatcgaaag gccgcaggtc gacgggaatc gacaaggcgg
     9181 cggaaacctc ccgcacggcg tcgacgagac cgggaacggc gcgggtggcc tggacgaatg
     9241 cgccgcccat ttcacttccg tgcagggtga attggaactc cgggcgcagc tcatccagca
     9301 gcgcaagcag aatttccgat tccggcagcg gacggcgttt ttcgccgggc gcgggaagga
     9361 attcaggctg gcttgcgaaa agtggccggt agaagccgtg aaagtattcc cggacacccg
     9421 gcaggccgtg cagccaatcc ccgttgagcc gggatccatc cgggtcgaga cagagcagga
     9481 aatgccagga gcagtcggag tcctcaagaa gtccgccccc cgcggccgtc ccgatggtac
     9541 cgccggagcc acccaggagc agctccgcga gccgcagcga agtcgcccct cccacaggct
     9601 cgttggcatg ggctccggcc accaggagta cattgcgcgc accgtggccc acggtgagca
     9661 gaagcaacgg gtcgcccgcg cgggagctgc ccaggcgcct taatcgaatg gccttcggat
     9721 ggcgccgcgc catcccgtga gcgacatgaa ccaggtcatc gaccgatggg taccccatga
     9781 tgctgttcaa cgacaccctg aatccaagtc tctggggcgg cgcggcgccg gacgtggtta
     9841 cgtaccgatg gagttgctct cccccgtcgt ctccttcttg tccagcggtc gtatctcgat
     9901 acgggtcatg ccgccccctt ccaatggcct gacgtcttgc cagtgttcgc ccggcggggc
     9961 agagtgtcaa gggttggact cgccaattgg acgggaacac atggctgttg aagcgttatg
    10021 gaagccgcgg atcaagccgg agcatgccgc ttatcgcacc accgaaggga acatccgtat
    10081 cggcagtgtc atcttcggaa tcggtgccga gatcaaggac cccgccggat ggctgtggac
    10141 gctggcatcg ggagcggacg gcacccgcac ggaagaggcg ctcatcgggc acgtgctcgc
    10201 gggccatccc gagcttcctg agctgacgga ggacgaggtc ggcgacgcgc tgcggcagct
    10261 gaacgaggcg ggcttcgtcg aggatgccgc cgccgaacgg cccgccgccc tgtccgaacg
    10321 ggaggccgag cgctacagcc gcggcgtgcc gctgctgcgc tggatggacc tctccccgcg
    10381 ccgcaacgcc tgggaggcgc aggcgcggct gaaggagtcc gccgtcctgc tgatcggcct
    10441 cggcggcgtc ggcggcatgg cggcgcaggc cctggtggcc tcgggcgtcg ggcgcctgca
    10501 ctgcgtggac tccgaccgcg tcgagctgtc caacctcaac cggcagactc tctaccgcga
    10561 agcggacctc ggcagcggca aggtcgccgc cggggtggcc cacttgcagg cgctgaactc
    10621 cgatgtgcgg gtcaccggcc aggagacccg cgtcggaacg cccggcgagc tggcggcgct
    10681 gctgtcccgg ccgcccgccg gggcgggggc gtgggacgcg ctcctgctgt gcgccgacca
    10741 gccctcggac atcaggcgct ggaccaacct gacctgcctg accgcgaggg tgccgtgggt
    10801 ggacggcggc tatcgcggac cgctcatcac cgtcggcgtg taccggccgg gccggggcgg
    10861 ctgctacgaa tgcctgcgga ccgccgaata cgcccggcgg gacctgcggc tcgccccggg
    10921 acaggacgag tcgcgggccg ccccgcgcat ggcatggaac ccggtgaacg ccgtgacggc
    10981 gggcgtcgcg ggcagcctga tggcccacgc ggtgctgacg ctgctcaccg gcatcccgcc
    11041 gaccgagccc ggcttccgct tcggcgtcaa cctgatggca ctcgacgacg ccacctacac
    11101 gcgtgacccg gcccgccccg actgccctgc ctgcggcacg ggcaggtgag gagccgagcg
    11161 tggccgtcgc gccggccgca ccggcaggcg ccgcagccac gggcagcctg ccgggcggaa
    11221 tctcccggaa cctgccgaac cccagcagcc ggacgtggcc gagccgggga cgtccggctt
    11281 cgatccggga cacgaccggg gccgagcagc tgccaccgtc accgacgtga gcccgggtca
    11341 ggcggcgggc gcagcggacc cagcgggcgc agcggcgaac cgcaccgttc gctgggccca
    11401 cgcccgccgc gtccggcagc gcccggcggc gccggatcag tcgggcgcgc gcccggtcgc
    11461 gcggccgggc gaacagccgg acgcgccgca gcaccgctgc aaggcgggca cccacgcggc
    11521 cggatgcggc cgcggtcctg aagagtgagc gcagcatcga ggtgcccccc gtcggtcgtg
    11581 cacagcggtc tcaccggctc gcccgctccc cggcgagcga gccgatgaca acgaccctac
    11641 gccgcgtcac tgacaaggca ctcccggtaa cgggccaccg tctccgccag cacctcctgc
    11701 ccgtcgcgtg cccacagccc gtcgttgaag atctccacct ccaccggccc gcggtacccc
    11761 gcctccgcca cggcgtcccg gaaccaccgc atgtccaccg cgccgtcccc gatctgcccg
    11821 cgcccgttca gcaccccggc gggcaacggc gtgacccagt cggccagttg gaagctgtgg
    11881 atacgcccgc ccgccccggc cctgcggatc tgcgcggcga cgcggtcgtc ccaccacagg
    11941 tggtacgtgt ccacgacgat gccgacctgc tcggccggga aacgttccgc caggtcgagg
    12001 gcctgctcca gcgtcgagac gacgcaccgg tcggcggcgt acatcgggtg cagcggctcg
    12061 atcgccagcc gcacgccgcg ctccgccgca taggggccga gctcggccag cgcgtcggcg
    12121 atgcgttccc gcgcgcccgc caggtcgcgg ctgccggccg ggaggccgcc ggagaccagc
    12181 accagcgtgt cggtgccgag cgccgccgcc tcgtcgacgg cggcgcggtt gtcggcgagc
    12241 gccgccgccc gttccgccgg gtcgatggcg gtgaggaaac cgccccggca cagcgtggtg
    12301 accgacagcc cggcgtcggc cacgagcgcg gcagccgccg cgagcccgta ccgcgcgacc
    12361 ggctcgcgcc acagcccgac ccccggcacg ccaagaccga cgaggccgtt gaccagctcg
    12421 ggcaacggca gctgcttcgc ggtcatctgg ttgatggaga acccggtgag gtcggtcact
    12481 gcgccacccc gtgcaccgcg agcagccgcg ccatccgctc cctggccagc gccgggtcgg
    12541 ggaacaggcc gagcccgtcc gccagttcgt acgctcgcgc cagatgcggc agcgaacggg
    12601 ccgactggag cccgcccacc atcgtgaagt ggtcctggtg cccggccagc caggccagca
    12661 gcacgacccc cgtcttgtaa taccgcgtcg gcgcccggaa caggtgccgc gacagctcca
    12721 ccgtcgggtc gaggtgcgcc cggaagcccg cgacgtcgcc ggtgtccagc gtccgcacgg
    12781 cctcggcggc cagcggcccg agcgggtcga agatgcccag cagcgcgtgg ctgaagccct
    12841 gctcgtcgcc cgcgatcagc tccgggtagt tgaagtcgtc gcccgtgtag cagcgcacgc
    12901 ccgagggcag ccgccgccgc agcttgatct cgcgctgggc gtcgagcagc gacaccttga
    12961 ccccgtccac cttgtcggcg tgggtcccga tgatgtcgag gaacgtgtcg gtcgccgcgt
    13021 ccaggtcctc gctgccccag tagcccgtca gcgccgggtc gaacatcggc ccgagccagt
    13081 gcaggacgac cggctcggcg gcctgccgca gcaggtgccc gtacacctcc gcgtagtcct
    13141 cagggccccg ggccgccgcc gccagcgccc gggaggccat gaggatcgcc tgcgcgccgg
    13201 tctcctcgac caccgcgagc tgctcctcgt acgcggcgcg caccgcggcg gtgtccgccg
    13261 ggccggtcag ctggtcggtg ccgacgccgc acgcgatgcg cccgcccgcc gcgcgcgcct
    13321 ccgcgccgga acggcggatc agctccgcgg cccccgccca gtcgaggccc atgccgcgct
    13381 gcgcggtgtc catcgcctcc gccacgccca ggccgtgggc ccagaggtgg cggcggaacg
    13441 ccagggtggt gtcccagtcc acggccgccg gcccttcggg cgtcgtgtcg gcgaacgggt
    13501 cggcgacgac gtgcgccgcc gagaagacga tgcgggaggt gagcggcgcg ccccccggcg
    13561 cggggctcgc aggcacggcg cgcggccggt actcgcgcaa ctggccgccg ggttcgggca
    13621 gccggatcac ttcggtcacg ttctggccct cctcacgggc tcggtcatca caggctcggt
    13681 catcacaggc tcggtcatca caggctcggt catcacaggc tcagctcggg aacggtcagg
    13741 cggcggccgt ccgccgagga cgcgagcccc agctcggcga gctgcacgcc ccgcgcgccc
    13801 gccagcaggt cccaggtgta cggctcgtcg agcaccacgt gccggaggaa cagctcccac
    13861 tgtgccttga agccgttgtc gaactcgccg ttgtccggca cctcctgcca ctgctcgcgg
    13921 aacacctcgg tggccggcag gtccgggttc cacaccggct tcggcgtggc cgaacggtgc
    13981 tgcgcccggc agttgcgcag accggcgacc gcggagccct cggtgccgtc cacctggaac
    14041 tccaccagct cgtcccggtt gacccgcacc gaccaggacg agttgatctg cgcgatgatg
    14101 ccgccggcca gctggaagat gccgtacgcg gcgtcgtccg cggtggcctc gtagggcttg
    14161 ccctgctcgt tccagcgctg cgggatgtgc gtggcggcca gcgcctgcac ggtctccacg
    14221 cgcccgaaca gctcgtggag cacgtactcc cagtgcggga acatgtcgac gacgatgccg
    14281 ccgccctcct cggacctgta gttccaggag gggcgctggg cgggctgcca gtccccctcg
    14341 aagacccagt acccgaattc gccgcgcacc gacaggatgc gcccgaagaa gccgccgtcc
    14401 accagccgct tgagcttctg gagccccggc aggaacagct tgtcctgcac caccccgtgc
    14461 ttgacgcccg cgtccgcggc ctgccgggcc agcgccagcg cgccctccag ggaggtcgcg
    14521 gtcggcttct ccgtgtagat gtgcttgccc gccgcgatgg cctgcttgat ggccgcctcg
    14581 cgggtcaggg tgatctgcga gtcgaagtag atgtcgatgc cgtcgtcggc cagcaccgcg
    14641 tcgaggtccg tggtgaccgc cgcctcgggg tcgaggccgt gccgccgcgc gatctcgcgc
    14701 agcgcgtgct cgcggcgccc gaccagcacc ggctcgggcc agatcaccga gccgtcgccg
    14761 aggtcgacgc cgccctgttc ccggatggcc aggatcgaac ggaccaggtg ctggcggtaa
    14821 cccatgcgcc cggtgacacc gttcatggcg atccggacgg tcttcttcgt cgtcatgccc
    14881 ttccctccca gaaaacacag taagcgcttt ctatccgtgg agaagctaac ctctccccag
    14941 cggctaggac aagtgggagc agagcatgtc agtcacgctg gcggacgttg ccgcccgcgc
    15001 gggggtgtcc gcggcaacgg tttcccgcgt tctcaacggc aactatcccg tggcgggagc
    15061 cacgaggaac cgggtgctgc gcgccgtcga agagctggag tacgtggtca acggcccggc
    15121 cagcgccctg gctgccgcca cgtccgacct cgtcggcgtg ctggtcaacg acatcgccga
    15181 cccgttcttc gggatcatgg ccggcgcggt gcagtccgag atcgggcacg ccacgcgcaa
    15241 gctggccatc gtctgcaata ccggcggctc cccggagcgc gagctgacct acctcacgct
    15301 cctccagcgg caacgggcgg cggccgtcgt gctcaccggc ggggcggtgg aggacccggc
    15361 gcacggggaa gcgctcgccg cccggctgcg gcggctggac gccgcgggca gccaggtcgt
    15421 gctgtgcggc cggccgccgc tcggcgcggc cacggccggc ccgcacccgc tgaccgtgac
    15481 gttcgacaat cggggcggcg cccggcgcct gaccgaccac ctgctgaccc tcggtcaccg
    15541 ccgcctcggt tacctcgccg gcccggccgc caggacgacc acccgccacc gtctcgaagg
    15601 ccaccgcacc gccatggcgg ccgcggggct ggccgacgac gcggaacggc tgacggcgca
    15661 cggcgcgtac gaccgcgcct ccggctacga cggcgcgctg gaactgctgc gccgcgaccc
    15721 ggacctgacg gccattctgg ccgccaacga cacggtggcc ctcggcgtct gcgcggcgct
    15781 gcgcgaccgc ggcctgcgca tcccgcagga cgtgtccgtc accgggttcg acgacctgcc
    15841 gttcgcggtg gacgcgatgc ccgcgctcac cacggtccgc ctcccgctgc acgccgccgg
    15901 cgcccgcgcc gggcgcctcg cgctcggccg cgaggacgcg ccccccggcg gcgtcgccac
    15961 gttccgcggc gacctgatgg tccgcgactc cacggcacca ccccgccgct gacccgggac
    16021 gccccgggaa ccgtcggagt ccggcccggg cgggggcccg gggcgggaca cggatttccg
    16081 acgaacggcc gggcccggcc cggcccggca acggccggac ggccaggaac gaccagggcc
    16141 ggacgcccgg aaacccccgg gcacggtcag cgggcaacgc gccccgacga acgccccaga
    16201 cccgagcccg gaacggccaa ggccacgccc cggcgaacgg cccggaaccc cccgggcacg
    16261 gtcggcgggc aacggactcc ggcggacgcc ccagacccga gcccggaacg gccaaggcca
    16321 cgccccggcg aacggcccgg aaccccccgg gcgcggccgg cgggcaacga accccggcga
    16381 acggccgggg cgccgcccgc cgcgggctcg cgggaacgat cccggcgggg cggttggacg
    16441 gcggacgggc ggggccgggc ggggcggtcg gctcatgccg tcgttcggag ggtctccgtg
    16501 cggctcagga atttgtggaa gaagctggcc ggctgcagcg tgcccgccgg atcggacgcg
    16561 tagtccggca cctcgccgta cttggtccag cccgcggacc ggtacaggtg ctccgcggtg
    16621 ctgcccgtct cggtgtcgag gagcagcagc gtcactcccg cggccgtcgc cgcccgctcg
    16681 gccgtggcca gcagcgcggc ggccgtgccc cggccgcgcg ccccggggtg caccatcagc
    16741 ttcgctatgt ggccgcgatg ccgtccgttc tgctcggggg cgagggccag gctgacggtg
    16801 ccgaccagcc gcccgccgga ccgcgccgcc cacaccgtca ggccgccgtc cgcgagcgcg
    16861 ggggcgcgcg ccgcccacca ggccgccgcg tccgcgcggc cgaagggccg cacgaagccg
    16921 agcgaggcgc cgtccgcgac cacgtcggcc agcagggcgg cgagctcctc cgcgtgtgcc
    16981 agcagctcct cgggcgcgga cagccggacg atcacggtgc tcacggcagc accaccacaa
    17041 cggcgtaccg gacggccgcg ggtccggggc agtggtagcg cgaggggccc cagagccgga
    17101 accgcacgca gtcgccccgc cgcagcccgt gcgtctcctc ccccaccgtg acctcgacgg
    17161 cgccgtcgag cacccacacg tggtgctcga gcccgggcac gggcggcgcg tcgtaggcga
    17221 tggcggcgcc gggccgcagc tcgccctcga tcacctcggc gcgcagcccc gcgtgcggcg
    17281 gcgagaccga gcgccggacg aacccggcgg aggcgtcggc ccacacctcc tgccggccgg
    17341 cgcgcaccag gccgggcggc tcccgttcga cctcgctgag caggcgcgac atcgtgcgct
    17401 cgtagacggt gcacagcttg ccgagcatgg ccgcggtggg gctcagctcg gcccgctcca
    17461 cgcgcgagag cgtcgaacgg ctcaccccgc tgcgctccgc cagctcttcg agcgaccagc
    17521 cccgctcgcc gcgcagctcg ccgagccgcg ccgccagcct ggcgtcgacc gacccgtccg
    17581 gcggaccggc cgccacctca gtgcttccca catccgggag catatcccag accagagaca
    17641 gcgaggatcg tctagggtcc cgccatggcc acccagaagg aacgcatgct cgccggtgag
    17701 ctgtacatcg ccgacgaccc cgaaatcgcg gccgacgccc tgcgcgccgt gcagctctcc
    17761 gaacggttca acgccaccgc gaccgccgat cccgagacca ggcgggcggc gctggccgcg
    17821 ctgctcgggg aggtcggcga gggcaccgag gtgcggcccc cgttccacgt cgactacggg
    17881 caccacatca cgatcggccc gcgcacgttc gtgaacttcg gcgccgtctt cctcgacgtc
    17941 gcccccatca ccatcggcgc ggacgtccag atcgggccga acgtccagct gctcaccccg
    18001 acccatccgg tcgaaccgga gccgcggcgc gagaagtggg aggcggcggc ccccatcacc
    18061 atcggcgaca acgtgtggct cggcggcggc gtcatcgtct gccccggggt caccatcggc
    18121 gagaacaccg tggtcggcgc gggtgccgtc gtcaccaagg atctgccgcc aggcgtcgtc
    18181 gcggtcggca accccgcccg cgtcacccgg ggcgtctagc cgcgcacaca ccgtgcggcc
    18241 gtcggtcgcg gggggccatc cccgcggcta cggtggtcgg gagggccact gaagccggga
    18301 ggtgcaccac gtgacttccc tccgccgcgg cggcaagggc ggcgcgttca ccctgctgct
    18361 cgtctacctc gcgctgctca cggccctcca gatctggtcg gggcacaaca acctcaccgg
    18421 ctggtccgcg tattcggtgc tcgcgccgat ggccgcgagc gccctgctca ccatgcgcgc
    18481 cactctcgtg gtgggcctgc tgaccatcgt ctccgtgatc atcgcctacg gcggcagcat
    18541 cccggggctc tccagcggca cccggggcgt catcgtctcc tcggccgcct gctcgaccgt
    18601 gctcgccatg gtgatctgcc gcatccggct gaaccgggag gcccgcgtca gccggctcac
    18661 gatcgcccgc gaacggctga cgctgctccg cgtcgccagc cgccacgtcg gcagcacgct
    18721 cgacgtgcgc cgcacggcgt gcgaggtcac cgagatcgcc gtacccggct tcgccgacct
    18781 ggtcacggtg gacctgtacg agtcggtgct gcgcggcgag gagcccgccg ccccggacgg
    18841 caacccgctg cgccgcgtcg cgcagcgctc cgtcgcggac gaggagtcgg cggacgaggg
    18901 cgcgcgggac ggcgcgaacg gaccggacgg accggacgga ccggacggac cggacggacc
    18961 ggacggacag caggaacagc aggaacagca gcaacagcag gaggaacagg agaggaccga
    19021 cgagaaggag gcgtacgagg gcggcacccc ggccttgggc caccacctga cccagggccc
    19081 cgacgtgcgc gcccgcatcc tggacgactc cgacgtcggg acctggctgg cggcgaaccc
    19141 gcggtacgcc gcccaggcca ccgcgggcac cagccgctcc ggcatcgcgg tgccgctgcg
    19201 cgcccgcggc accaccctcg gcgtggccgt cttcgtccgg cacctgcggg ccgacccgtt
    19261 cgacgcggac gacctgctgc tcgccgagga gatcggcgcc caggccgccg tctgcgtcga
    19321 caacgcccgc cggtacaccc acgagcaccg ggcctcgctc accctccagc agagcctgct
    19381 gccgcgccgg ctgcccgagg tcgcggccgt cgaggtggcc acccgttacc tgcccgcgga
    19441 ctcgagcgcc ggggtgggcg gcgactggtt cgacgtcatc cagctgtccg gcgcccgggt
    19501 ggcgctggtc gtcggcgacg tggtggggca cggcctgtac gcctcggcga cgatggggcg
    19561 gctgcgttcc gcggtgcgca ccctcgccga catcgacctg gcgcccgacg agttgctcac
    19621 ccacctcgac gacgtcgtca tccggctgcg tctcgagacc gagggcggcg agcaggaggg
    19681 cggggcccag gagaacccgg ccggcgcggt cggcgccacc tgcctgtacg ccgtgtacga
    19741 cccggtctcc cgtacctgct cgatggcgcg cgccggccac cccgcgccgg cgctggtccg
    19801 gccggacggg cgcgtggagt tcatcgacgc gccgccgggc cagccgctgg ggctcggcgg
    19861 gctgccgttc gaggcccacg aagtgctgct gccggagggc agctacctcg ccctctacac
    19921 caacgggctg atcgcgcgcc accacgacat ggaacgcggg caggcgacgc tccggcaggc
    19981 actctcccag ccggtgcact cgcccgaggc ggcctgcgac gccgtcctca gggccatgct
    20041 cgacggggag cccaccgacg acatcgccct gctcgtcgcc cgcacccgcg cgctggacgc
    20101 cgcgcacgtc gcgagctggc acatccccga cgacccgacc gccgtcgccc acgcccgcga
    20161 gctggccgaa ggccagctga cctcctgggg actcgaggag gccacgttca ccatggaact
    20221 cgtcgtcagc gagcttgtca ccaacgccat caggcacgcg gacggaccca tccagctgcg
    20281 cctcatccgc gagcccgcgg ccctgatctg cgaagtgtcg gacaacagca gcacctcacc
    20341 gcacctgcgc cgggcgcggg tcttcgacga gagcggccgg ggcctgttca tcgtcgccca
    20401 cctgaccgcg cgctggggca ccaggcacgg ccgcgagggc aagacgatct gggccgaact
    20461 gtcgtcctcg ccctcgcccg aagggctgct cgccgccggc tgacgccccg gccggccgcg
    20521 gcgcgccgcg tcgcgcttcg cctacgcttc cggcatgacc gaatccgccg cgccgctcgc
    20581 caccggaccg ctgggtatgc ggctgctcgc gttcgaccgc ctgccggagg acacccggtt
    20641 cgaccgggag ccggccggct acgcactcgt ggcgctgtgg cacgcggggc tgctgctcct
    20701 ggtgcacgaa cgcgaccggg actgctggga gctgccgggc ggcacgctgg acccgggcga
    20761 gacgccgcgc gaggccgcgg cacgggagct ggccgaggag tcggggcagc acgtcgcgcc
    20821 ggagcggctg cacttcgcgg gcttcgcacg gacgtggctg ccggaccggc cggtgctgcg
    20881 cggcgcgctg ttccacgccg aggcggacga acgggccgtg ttcgagccga cgccggagat
    20941 agccggcgtc cactggtgga acctgcggga cccgatgccg cacggcaggc tccagacggt
    21001 cgacgcttat ctggcggcgc tggtccgccc ctgaacggta cggttgcgcg catggggttc
    21061 gatttccgcg agcatcccga cggctccgtg cacatcacgc accacggccg ccgggcgacc
    21121 acgctgcgcg gcgcgcgtgc cctgcaatt
//
