LOCUS       NZ_LZNS01000001        21632 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2335690
            Orig. end                         :: 2357322
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21632
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="15"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21632
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21632
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11632](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11632)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(753..766)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.12"
                     /tool="antismash"
     misc_feature    847..861
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.42"
                     /tool="antismash"
     gene            930..1706
                     /locus_tag="STBA_RS10165"
                     /old_locus_tag="STBA_20590"
     CDS             930..1706
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010361047.1"
                     /locus_tag="STBA_RS10165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20590"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_077058934.1"
                     /transl_table=11
                     /translation="MTGAGAEAPDAHLERNRRYWDGQGNAAHGPLARAQWSRPEPHWGL
                     WATPESRVRVLPEDLTGVRAIELGCGTAYVSAWLARAGARPVGIDLSEQQLATARAMQG
                     EFGLDFPLVLGNAEQVPYEDGSFDLAISEFGASLWCDPHRWIPEAARLLVPGGRLVFMR
                     YSPLFALCAPPEGQASAALVRDQFGLGRLDWGQRVEFVLPHGEMIRLLRAAGFVVEDLI
                     EIQAPRPADREYGEVSSDWAHRWPSEEIWTARRSCG"
     gene            complement(1720..2322)
                     /locus_tag="STBA_RS10170"
                     /old_locus_tag="STBA_20600"
     CDS             complement(1720..2322)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063285.1"
                     /locus_tag="STBA_RS10170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20600"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_077058935.1"
                     /transl_table=11
                     /translation="MTERKPRKDAVRNRAATLAAADALFAGCRSPEEVTMADIAAAAGV
                     GKGTLFRAFGDRTGLIRALYEARLEPIRKAVEAGPPPLGPATPPLQRVPALLDAVLTFK
                     LDNRHLALALEGTGDDSPYRAEHYERWHALLRDLLARIPGLTGSDFTAHALLAATRADL
                     VEHLAGHKGVPREDLRRQLAGFTATILAAARAPATMD"
     misc_feature    2330..2344
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 15.67"
                     /tool="antismash"
     gene            2414..2839
                     /locus_tag="STBA_RS10175"
                     /old_locus_tag="STBA_20610"
     CDS             2414..2839
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579069.1"
                     /locus_tag="STBA_RS10175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20610"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_077058936.1"
                     /transl_table=11
                     /translation="MPETTSPADLYHHSLRLLLAKDIPAWVGLWADDGVLEFPFAPRDW
                     PRRLAGKEAIAAYMRHYPDHIDLHEFTDVRVHRTAEPGTIVVEMRGVGRLVETGSPFDA
                     NYIAVVAVRDGLITSCRDYWNPLVAQEPGADFTRSGR"
     gene            2836..3684
                     /locus_tag="STBA_RS10180"
                     /old_locus_tag="STBA_20620"
     CDS             2836..3684
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494339.1"
                     /locus_tag="STBA_RS10180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20620"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_077058937.1"
                     /transl_table=11
                     /translation="MTAAGTTLVIGANGTTGSRTTARLVGAGHRVKAAGRRAARVPGAE
                     AVRFDWYDPGTFGEALAGTDRVYLVPPPGDLDPAAVMLPFLRQARGTGVHRAVLLSSSA
                     VPAGGPAVGAVHRALPGLFDAWAVLRPSWFMQNFTGTHLHAHSIRDDGVILTAAGTGRV
                     GFVDADDIAAVAVHALTDDRAPCTDLVLTGPETLSHDDVATIVTEVTGRPVTHRHLSAE
                     QLRDRLAATIPRDFAALLADLDLAIAGGAEDRTTDTVRRLTGRPPRSFLAVAERELTRS
                     G"
     gene            3933..4634
                     /locus_tag="STBA_RS10185"
                     /old_locus_tag="STBA_20630"
     CDS             3933..4634
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090327.1"
                     /locus_tag="STBA_RS10185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20630"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_077058938.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.9e-16, bitscore:
                     59.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.2e-12, bitscore: 45.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLHTRTWGEGDRVALLVHGIMADHRTWRRVGPALADRGFRTIAV
                     DLRGHGLSGRGTYAPADFADDLAETLPTGAALALGHSLGGLALALAAERLRPARAVYAD
                     PAWRLFDGRRHDPVALISAKDATREAIAAGNPRWEPADVDTEVATLARWDSRTAFGLSR
                     LAHEDFTPDDPRVPSLVQIPGDGGLVTADHAARLRKRGFTTATLPDTGHTMHRDDFDAF
                     MTALDHWLAGN"
     gene            complement(4660..5769)
                     /locus_tag="STBA_RS10190"
                     /old_locus_tag="STBA_20640"
     CDS             complement(4660..5769)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018549377.1"
                     /locus_tag="STBA_RS10190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20640"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_253194626.1"
                     /transl_table=11
                     /translation="MSADEDPVRARYLAGWAAILAEVSRTGRRLDRDEIRGRRELGERA
                     AREGIGLRELVRGHLAATRAAFRDLPGVAAAPGARQVRSAAESVLAAAEQAVDALAEGY
                     GRAQLLAVRRDEAARREFIDDLLHGRSDPGDLSARALRFGLHLAHSHSVAVACGPQPYD
                     DTHAVTRRAADTLEGRFGEQLILLATKDGRLVCIAPGSRPEIGEYFATTARASDGTPGQ
                     WRVALGRPRPGPGGIVESYEEARAALELAARMRLSTPVLRAAELLVFPVLTRDRQAMAD
                     LVRSVLGPLAAARGGAAPLVDTLDAYFDAGCVAAEAARRMSLSVRALTYRLARIQRLTG
                     ADPADPLQRYTLQTAVIGARLLGWPEQEI"
     gene            complement(5850..6635)
                     /locus_tag="STBA_RS10195"
                     /old_locus_tag="STBA_20650"
     CDS             complement(5850..6635)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016162.4"
                     /locus_tag="STBA_RS10195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20650"
                     /product="DUF427 domain-containing protein"
                     /protein_id="WP_077058939.1"
                     /transl_table=11
                     /translation="MTLTLSHGPLSAAPPPTVNYRLTGPAHRLFWHPFPRRVRALVGGE
                     TLLDTRNGRLLHETGLLPQLYVPADDVRTQLLRPSDHTTECPFKGQAAYWSVDAGGRRV
                     PNGVWAYPEPIAGAEWLAGWYALYWAAADAWFDEEEEVHGHLRDPYHRVDARRSGSTVR
                     VLLDGTTLAETARPVLLSETGLPNRWYVPPEDVRRDLLAESATRTVCPYKGTAHYWSFT
                     GGGEPVADVAWSYPEPLEEATRAGGFLCFDHERITTEVG"
     gene            complement(6757..7284)
                     /locus_tag="STBA_RS10200"
                     /old_locus_tag="STBA_20660"
     CDS             complement(6757..7284)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS10200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_20660"
                     /product="hypothetical protein"
                     /protein_id="WP_077058940.1"
                     /transl_table=11
                     /translation="MGDSNWWIGLITGATAVVASWVAGRGATRSARVQAEVTAHAAQVA
                     EARSRRRDAYREMSAAAHGLSEVFWRIEEADAAPPGEPRAAVLAQLRADGRAALNEVTR
                     ASREVVLEGPAPVAGAAQTLRLRAITTSRLLTRLTTGDEDAERARFDAAYRDFREEHLT
                     FLELARAALDVG"
     gene            complement(7328..8575)
                     /locus_tag="STBA_RS10205"
                     /old_locus_tag="STBA_20670"
     CDS             complement(7328..8575)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014628741.1"
                     /locus_tag="STBA_RS10205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20670"
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_077058941.1"
                     /transl_table=11
                     /translation="MSTPAATVAQTTLDRIFMDFARREGERDWQIGALLTFPGPAPMVA
                     EVAAHLAGRLPHAPELTYRPAGAGRRAHWAADPDFDAARHVQAFDLPPGEGPLADRMLT
                     ALLARPPAADRPLWDVWVIRDGRGFGLCYRAHHAFQDGLAVARTVELLFGRQPRPAPTA
                     PADPLPGPGAARRLAALRHVLPLPRRRARWSALDVPRSDRRAASTAETELPRLYAIGRA
                     TGAGVTQVCLAAATAVLREAYAADFPGPEDGVYASLGITARRPAEPFPRLGNRAAGATL
                     PLPCGEPSAARRLQLVAQNTAFARLAEMAQEDGALLRLPHRLAQRGMDRWLDARFVPLA
                     VADVRTRGPLAFRGTPAAALHPLPIGSPRTRLFIAWTAYRGRLHVTFLGDAALPGLADL
                     PDRWHRAVDALARAVP"
     gene            complement(8572..9789)
                     /locus_tag="STBA_RS10210"
                     /old_locus_tag="STBA_20680"
     CDS             complement(8572..9789)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (70-403). E-value:
                     6.5e-59. Score: 191.8. Matches aSDomain:
                     nrpspksdomains_STBA_RS10210_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358956.1"
                     /locus_tag="STBA_RS10210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20680"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_077058942.1"
                     /sec_met_domain="t2fas (E-value: 6.1e-117, bitscore: 389.5,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 9.7e-43, bitscore:
                     145.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGRGAVCVTGVGTVTPAGDGRDATWKRVCQGLPTAALDDEGQPP
                     RLACRVPPFGPGRLNGLLARKPDRCVQLALLAAREAVADAGLDPGGWDGARVAVVAGAG
                     CCGAQTYEAQHRVLLDAGQHGMSAFSVPGALGNALAAQLAMDLHATGPGLTVNTACASG
                     ATAICTALDLLALDRCDIAVAGGAEAPLTPFFQAGFDRMHALSSRFGDPAGALRPFDAD
                     RDGFVMGEGAGMLVLERERDARARGARPRARVAGQGATSDAHHIVKPDPGGRGLAAALR
                     QALAAAGAAPADVAHVNAHGTGTPLGDRVEAGVLAEVLPHRPPVTSTKAVTGHLLGAAG
                     AVEAALTVLAVERRLIPPTANLAAPSPGIDLDLVTTPRPRRLPLALSVSTGFGGHNVAL
                     AFAEAS"
     aSDomain        complement(8581..9579)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STBA_RS10210_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="6.50E-59"
                     /label="STBA_RS10210_PKS_KS.1"
                     /locus_tag="STBA_RS10210"
                     /protein_end="403"
                     /protein_start="70"
                     /score="191.8"
                     /tool="antismash"
                     /translation="VQLALLAAREAVADAGLDPGGWDGARVAVVAGAGCCGAQTYEAQH
                     RVLLDAGQHGMSAFSVPGALGNALAAQLAMDLHATGPGLTVNTACASGATAICTALDLL
                     ALDRCDIAVAGGAEAPLTPFFQAGFDRMHALSSRFGDPAGALRPFDADRDGFVMGEGAG
                     MLVLERERDARARGARPRARVAGQGATSDAHHIVKPDPGGRGLAAALRQALAAAGAAPA
                     DVAHVNAHGTGTPLGDRVEAGVLAEVLPHRPPVTSTKAVTGHLLGAAGAVEAALTVLAV
                     ERRLIPPTANLAAPSPGIDLDLVTTPRPRRLPLALSVSTGFGGHNVALAFAE"
     CDS_motif       complement(8857..8901)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS10210_0005"
                     /evalue="1.10E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="STBA_RS10210"
                     /protein_end="311"
                     /protein_start="296"
                     /score="11.4"
                     /tool="antismash"
                     /translation="VNAHGTGTPLGDRVE"
     CDS_motif       complement(9097..9135)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS10210_0004"
                     /evalue="4.80E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="STBA_RS10210"
                     /protein_end="231"
                     /protein_start="218"
                     /score="10.3"
                     /tool="antismash"
                     /translation="FDADRDGFVMGEG"
     CDS_motif       complement(9154..9186)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS10210_0003"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m5"
                     /locus_tag="STBA_RS10210"
                     /protein_end="212"
                     /protein_start="201"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="MHALSSRFGDP"
     CDS_motif       complement(9292..9339)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS10210_0002"
                     /evalue="5.00E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="STBA_RS10210"
                     /protein_end="166"
                     /protein_start="150"
                     /score="12.6"
                     /tool="antismash"
                     /translation="GPGLTVNTACASGATA"
     CDS_motif       complement(9730..9756)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS10210_0001"
                     /evalue="6.30E+01"
                     /label="PKSI-KS_m5"
                     /locus_tag="STBA_RS10210"
                     /protein_end="20"
                     /protein_start="11"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="VGTVTPAGD"
     gene            complement(9786..10019)
                     /locus_tag="STBA_RS10215"
                     /old_locus_tag="STBA_20690"
     CDS             complement(9786..10019)
                     /NRPS_PKS="Domain: PP-binding (12-66). E-value: 1.8e-11.
                     Score: 36.2. Matches aSDomain:
                     nrpspksdomains_STBA_RS10215_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146311.1"
                     /locus_tag="STBA_RS10215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20690"
                     /product="acyl carrier protein"
                     /protein_id="WP_077058943.1"
                     /sec_met_domain="PP-binding (E-value: 6.4e-09, bitscore:
                     34.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFDDLKAALVSMGVPEEEITEQAGREEAGLDSLGIAELVLILKQ
                     RHGLTITEEELHEAGTVGDVLGIIAGHAAAGA"
     aSDomain        complement(9822..9983)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STBA_RS10215_PP-binding.1"
                     /evalue="1.80E-11"
                     /label="STBA_RS10215_PP-binding.1"
                     /locus_tag="STBA_RS10215"
                     /protein_end="66"
                     /protein_start="12"
                     /score="36.2"
                     /tool="antismash"
                     /translation="MGVPEEEITEQAGREEAGLDSLGIAELVLILKQRHGLTITEEELH
                     EAGTVGDVL"
     gene            complement(10001..11632)
                     /locus_tag="STBA_RS10220"
                     /old_locus_tag="STBA_20700"
     CDS             complement(10001..11632)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="STBA_RS10220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20700"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_077058944.1"
                     /sec_met_domain="T2TS (E-value: 6.6e-39, bitscore: 132.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATRCPAPRRDPRPPGPRGPALTTVVEAAAADLLARRAPEGHWR
                     GGCRGRLLEAALAVRLLRDTGAAPHARRAVERFCARELAAPPAAHTDPFDRLLSRYLAA
                     AALGRPEPSGGAARLRAALAGHRAVASLRKRALLGALLTLLRPGEAWDVPDVPPDPLAA
                     GGGGWLRPTLAAVRLLTGRHGCGAARADLALLRESQSCDGSWDQYVLGTVTILLVLRER
                     RLAPDVVARGVDFVVAQIRADGGVPFISSQDVWLTCLASLTLAESGVGEDRLAASADYL
                     CHAQLPDGGWGYAPGVTHADADDTAVAVTFLRRCAAPQARDAAAAGAAWLRRAQNADGG
                     FNTYTGGSRSEAEITAKAVLALLAGQPGPAERAAAARGWSWLAARQRLDGGYPYEWTRS
                     AAFPLLHVMRAARAVAAHELGGTGRVMARAAACLRQGAAGPLGTAYAVGALAAAGREAA
                     ALAAGVRLLTATGPEAAVPPDALGPRPFVYDVPLLYPVYRLGGLAAARDLAAARHGSAA
                     GSPRNGPRNSLRNSPRNRRKPCHSTI"
     misc_feature    complement(11790..11805)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.71"
                     /tool="antismash"
     gene            complement(11826..12416)
                     /locus_tag="STBA_RS10225"
                     /old_locus_tag="STBA_20710"
     CDS             complement(11826..12416)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010637626.1"
                     /locus_tag="STBA_RS10225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20710"
                     /product="DedA family protein"
                     /protein_id="WP_077063229.1"
                     /transl_table=11
                     /translation="MEALGAPGAGAAIALENLFPPLPSEVILPLAGFTASRGDMSLWAA
                     LLWTTIGSVVGAMALYWVGALLGRERLIAIAAKLPLVKVADIEKTEAWFSKHGAKAVFF
                     GRMIPIFRSLISIPAGVERMPVGTFLLLTTLGSAIWNTLFVLAGYRLGEDWERVTDLVS
                     VYSKVVLVVVVLAVLAFVVFRVTRAGGGKRRAS"
     gene            12609..13697
                     /locus_tag="STBA_RS10230"
                     /old_locus_tag="STBA_20720"
     CDS             12609..13697
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180056.1"
                     /locus_tag="STBA_RS10230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20720"
                     /product="histidine kinase"
                     /protein_id="WP_253194628.1"
                     /transl_table=11
                     /translation="MKKALHRWLRMATGLAMGAATVLPDLLVLYAALLLRRRGDPAAVR
                     LAGWERARVTRLHGDVPEATAPPEPRAALAYLAARLPVGLLAGLVLLSALVGAAYASTL
                     GWLWFWADHFWANVFSGVGGLFLLFLAAYAVQAVAALEAALVRRFLGPTRQEALERRIE
                     ELAESRAGVVAAVHEERRRIERDLHDGVQQRLVALGMLLGRARRRGDTDDLLAQAHQQA
                     RQALAELREVAWRVYPTVLDEAGLRAALEAVAERSPLPVRLDYRLAAEPDRPVAAVAYF
                     VVSEAVTNAVKHSGAAAVAVRLAGEGPALTVRVTDDGRGGADPAGGGLLGLARRAAALD
                     GRLSVASPAGGPTVITAELPCA"
     gene            13688..14332
                     /locus_tag="STBA_RS10235"
                     /old_locus_tag="STBA_20730"
     CDS             13688..14332
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180057.1"
                     /locus_tag="STBA_RS10235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20730"
                     /product="response regulator transcription factor"
                     /protein_id="WP_077058946.1"
                     /transl_table=11
                     /translation="MRVILADDSTLLREGLVRLLTEEGHEVTAAVGDAAALLAAVDRDP
                     PDVTVIDVRMPPTHSDEGLRAALDIRRRWPAVGVLVLSQYVEGRYATELLTGEPAGVGY
                     LLKDRVVEIDEFLDALERVAAGRTAFDPEVVRRLLARSSHTDPLARLTPREREVLHEMA
                     QGHTNATIAEHLWVSRSAVEKHVNAIFDKLQLPGPGGYSRRVLAVLRYLGS"
     gene            complement(14317..15702)
                     /locus_tag="STBA_RS10240"
                     /old_locus_tag="STBA_20740"
     CDS             complement(14317..15702)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482544.1"
                     /locus_tag="STBA_RS10240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20740"
                     /product="nucleotide pyrophosphatase/phosphodiesterase
                     family protein"
                     /protein_id="WP_077058947.1"
                     /transl_table=11
                     /translation="MTRPVVVLNVVGLTPALLDHLPRLAALARGGSRAPLGTVLPAVTC
                     SAQATFLTGAPPAEHGIVGNGWYFRGVGDVLLWRQHNALVGGEKIWDAARRVRPGYTVA
                     NVCWWYAMGADTDFTITPRPIYYADGRKDPDCYTRPSELHDELTSRYGPFPLFNYWGPT
                     ASIASSRWIAAAARHLLRTQRPDLTLVYLPHLDYDLQRFGPDSPQARAAAGELDAEIGP
                     LLDAAQAADATVVVLSEYGITPVDRPVDINRALRRAGLLDVYTQAGMEYLDPWVSRAFA
                     VADHQVAHVYVRRPEDLERTREVLAGLPGVAEVLDESGKKRHGLDHGRAGELVAVADPG
                     AWFTYYYWLDDAAAPDWAAIVDIHRKPGYDPAELFFDPADRFAKARAAAALARKKLGLR
                     YRMNVVPLDPSCVRGSHGRLPEDEKDRPVLLCSDPDALDGGEVAATAVKSFLLGLQGLQ
                     EPR"
     gene            complement(15699..16880)
                     /gene="eboE"
                     /locus_tag="STBA_RS10245"
                     /old_locus_tag="STBA_20750"
     CDS             complement(15699..16880)
                     /codon_start=1
                     /gene="eboE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972400.1"
                     /locus_tag="STBA_RS10245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20750"
                     /product="metabolite traffic protein EboE"
                     /protein_id="WP_077058948.1"
                     /transl_table=11
                     /translation="MRFQHPDGSVVHLAYCTNVHPAETLDGVLAQLRDYCEPVRRRLDR
                     ARLGIGLWLARDAARTLVADAGARRTLREALERHGLEVVTLNGFPYRGFGGERVKYAVY
                     TPDWTSRERLDHTADLAGLLAELLPGDEPEGTISTLPLAWRTPFTPQDQERALAHLTEL
                     AGRLDALAERTGRSIRLALEPEPGCIVETTGQAAEVLTAPGAPPSSRVGVCLDTCHLAT
                     AFEDPDRAIAGLTARGVPVVKAQLSAALHAEHPGEPAVRAALADFAEPRFLHQTRERAP
                     GGVLGHDDLDIALFGPEPLPGRDPWRVHLHIPLHARPHPPLTSTLPHLTQALTRLVGGE
                     RALTRHLEVETYTWQVLPPALRPRTPEGLADGIAAELSLARDLLTGLGLKELS"
     gene            complement(16887..17744)
                     /locus_tag="STBA_RS10250"
                     /old_locus_tag="STBA_20760"
     CDS             complement(16887..17744)
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494961.1"
                     /locus_tag="STBA_RS10250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20760"
                     /product="TatD family hydrolase"
                     /protein_id="WP_077058949.1"
                     /transl_table=11
                     /translation="MRIFDPHIHMTSRTTDDYERMRAAGVAAVVEPSFWLGQPRTSTAS
                     FLDYFDSLLGWEPYRAAQYGIAHHCTLALNPKEANDPRCTPVLQELPRYLEKDNVVAVG
                     EIGYDSLTPAEDDALAAQLELAARHGLPALVHTPHRDKAAGLERTLSVLAESELPPERV
                     VLDHLNETTVDRAADSGCWMAFSVYPDTKMDERRTVEVLRRLGLDRMLVNSAADWGRSD
                     PLKTRRVADAMLAAGFTDDDVDRVLWRNPVEFYGQSGRLELDGREQPESFEGNSILRGA
                     PAGR"
     gene            complement(17744..18301)
                     /locus_tag="STBA_RS10255"
                     /old_locus_tag="STBA_20770"
     CDS             complement(17744..18301)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037556.1"
                     /locus_tag="STBA_RS10255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20770"
                     /product="EboA domain-containing protein"
                     /protein_id="WP_077058950.1"
                     /transl_table=11
                     /translation="MLTETSLTPAARAWLDGVLGTDAWEAAFTSAGRHVGRAAADAVRV
                     ALLRAAGADAATAARLYRHGDAAERRAVLRALPHLPVGADALPLVEDALRTNDPRLIAA
                     AVGPYAARHLDQHLWRHAVLKCVFTDVPVTEVAGLADRADPELARMLTDFAAERTAAGR
                     PVPADVRHALALSPPPAPAPEA"
     gene            complement(18302..19153)
                     /locus_tag="STBA_RS10260"
                     /old_locus_tag="STBA_20780"
     CDS             complement(18302..19153)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326679.1"
                     /locus_tag="STBA_RS10260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20780"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_077058951.1"
                     /transl_table=11
                     /translation="MTGPRRPRFAYGTNGLTDLRLSDALALLADLGYQGVALTLDHMHL
                     DPCAPDLGRRTAQVARRLDRLGLAVAVETGARYVLDPTAKHGPSLLDPDPAARERRTGL
                     LLDAVRVGRDLGATAVHCFSGRVPRDTPEAEAWKRLAGALAPVLDLATAAGVPLAVEPE
                     PGMLLDTIAAFHRLRRDLDGVRLTLDLGHCHCLEPVPVPDCVTAAAPWTAHVQIEDMRR
                     GVHEHLPLGEGEINFPPVLAALAATGYGGLVSVELPRHSHAGPELARRSLDFLTTAHRE
                     AG"
     gene            complement(19150..20013)
                     /locus_tag="STBA_RS10265"
                     /old_locus_tag="STBA_20790"
     CDS             complement(19150..20013)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037554.1"
                     /locus_tag="STBA_RS10265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20790"
                     /product="SCO3242 family prenyltransferase"
                     /protein_id="WP_077058952.1"
                     /transl_table=11
                     /translation="MNRAWIELVRGPAALTVPGDIVAGAAAAGGAPLRRTALAAGSSLC
                     LYWSGMALNDWADRDTDARERPARPLPSGRIRPAAALAAAAGLTAAGLTLAAVHSRPAL
                     AAAGALAATAWAYDLGVKHTTAGPAAMGAARSLNVVLGACAGRAPHRALPAAGVVGAHT
                     AAVTALSRHEAFGGPRSAPLVTLAAALGTAAAVAAPGRTPAPRAERAGSVAGSVAYLLT
                     AAPPLLRAAREPTGARVRQGVVGGLTALMPLQAALAARAGRPQAVPVLLGALAAARRLS
                     RKVTPT"
     gene            complement(20010..21071)
                     /locus_tag="STBA_RS10270"
                     /old_locus_tag="STBA_20800"
     CDS             complement(20010..21071)
                     /GO_function="GO:0004512 - inositol-3-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006021 - inositol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579524.1"
                     /locus_tag="STBA_RS10270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_20800"
                     /product="inositol-3-phosphate synthase"
                     /protein_id="WP_077058953.1"
                     /transl_table=11
                     /translation="MTTASTARVGLWLIGARGSVATTTIAGRAALAAGLTPPTGMVTAL
                     PPFADSALPDLDRLVVGGHDIVDIPVPKRAEQLVAAGVLPHGLPAAIAAELAAADAEIR
                     HPGADPAADIADFTHRHGLERTVVVNVASTETDPAISTGYAAAAIAAGCSYINFTPATG
                     MRGPGLAERALAAGLPHAGRDGKTGQTLLRAALAPMFAQRALDVRSWSGTNLLGGGDGA
                     ALADPAAAAAKNAGKERVLADTLGDLPEGTVHIDNVPALGDWKTAWDHVAFDGFLGARM
                     VLQTIWQGCDSALAAPLVLDLARLVARAHATGMSGPVPGLGFFFKDPDTGPAALGEQYE
                     ELLTLAQTLRARP"
ORIGIN
        1 acgggtcgtc gtggtgcggg aagtcccgca tggcgaaggt gtaagcgaag cagccgtgca
       61 cgtcgcgggc cgcgtaaaga ccgatcagct ccccgaggta ggccgcctgg gtgccctcgt
      121 cccgctcgtg ccccggcttg atgcggggcg gatcggcgaa ccaccgcacg atgcggaacg
      181 agccgggccc tcggcgttcc gccccgcgga aggcgccgca gccgaactcc gtgatgacca
      241 cgggcttccc cgccgcctcc gcccgccgca gcagggcatc gagaccccgc tcgtaggccg
      301 ccgggtcgtc gccgaaccgg tagaggttga cgccgacgat gtcgaagtcc gaccagtcga
      361 cctgctccca gtaaccggcg gcgtaggtga ccgggccgtg gaagacgccg cgggcggtcg
      421 ccagggtctc ggcgagcagg cggcgcagct tgcgggtgat gcggcggtcg aacaaccgcc
      481 gccagcgcag gaggaactgg agccggacga agaccttggg gcccggcagc atgccgccct
      541 gcgtcagcga gaactcgctg ccgaccagca gcgtcacccg gcccgggtac cgcgcgcgca
      601 gctcctcggc accggcggcc atctccgtca ggtgggccag cagttcggcg cgcggccggt
      661 cggccaggta cggccgcacg tagacgtcga gcccctcgtc cagggcggca cgggcggccc
      721 ggagctgcga cccgatgtcg gtgccgatca gttgcacggc cgtgcagtgc aagtccgcgc
      781 ggatcgcgcg caggtcgcgg gccagcgcct cgtcctccgt ctcgccggtg acataggaaa
      841 tacccctgac agtcaggctc atgggacatg cataacacgg gccggttatt gcgttgcggc
      901 cccgggcggg gctccggtcg aatgcgggca tgaccggagc cggagcggaa gcccccgacg
      961 cgcacctcga acggaaccgg cgctactggg acggccaggg gaacgcggcg cacgggccgc
     1021 tcgcccgcgc ccagtggtcg cggccggaac cgcactgggg actgtgggcc accccggagt
     1081 cgcgggtccg ggtgctgccc gaggacctga cgggggtccg ggcgatcgaa ctgggctgcg
     1141 gcaccgccta cgtctccgcg tggctcgcgc gggcgggcgc ccgcccggtc ggcatcgatc
     1201 tgtcggagca gcagctcgcc accgcccgcg cgatgcaggg cgagttcggc ctcgacttcc
     1261 cgctcgtcct ggggaacgcg gagcaggtcc cgtacgagga cgggtcgttc gacctggcca
     1321 tcagcgagtt cggggcgtca ctgtggtgcg acccccaccg gtggattccc gaggccgcgc
     1381 ggctgctcgt gcccggcggg cggctggtgt tcatgcgtta ctcgccgctg ttcgcgctgt
     1441 gcgcgccgcc cgaggggcag gcgtccgcgg cgctggtgcg cgaccagttc ggcctcggcc
     1501 ggctggactg ggggcagcgg gtggagttcg tcctgccgca cggcgagatg atccggctgc
     1561 tgcgcgccgc cggattcgtg gtcgaggacc tgatcgagat acaggccccg cgccccgcgg
     1621 accgcgagta cggggaggtc tcctcggact gggcacaccg atggccgagc gaggagatct
     1681 ggacggcgcg ccggtcctgc ggctgaccgc ggcgcccggt cagtccatgg tggccggcgc
     1741 ccgagcggcg gccaggatgg tggcggtgaa gccggccagc tgtcgccgca ggtcttcgcg
     1801 cggcacaccc ttgtgcccgg ccaggtgttc gacgagatcg gcgcgggtgg cggcgagcag
     1861 cgcgtgggcg gtgaagtcgc tgccggtgag gccgggaatc cgcgccagca ggtcccggag
     1921 cagggcgtgc catcgctcgt agtgctccgc ccggtagggg ctgtcgtcgc cggtcccctc
     1981 cagggcaagc gcgaggtggc ggttgtcgag cttgaaggtc agtacggcgt cgagcagggc
     2041 gggtacgcgc tgaagcggtg gggtggcggg cccgagcggt ggtggtcccg cttcgacggc
     2101 tttcctgatc ggttcgagcc gtgcttcgta gagcgcgcgg atcagcccgg tgcggtcacc
     2161 gaaggcgcgg aagagcgttc ccttgccgac gccggccgcc gccgcgatat cggccatggt
     2221 gacctcctcg gggctccggc agccggcgaa gagcgcgtcg gcggccgcga gggtggccgc
     2281 ccggttgcgg acggcgtcct tgcgtggttt gcgctcggtc atgcgcgcct cctccacttg
     2341 caatgcggac ccggggtccg tatcgtccag caaagcggac ctcgggtcca catcttacgg
     2401 gacggagaag ttcatgcccg aaaccacctc accggcagac ctctatcacc acagtcttcg
     2461 actcctgctg gccaaggaca tacccgcctg ggtcggcctg tgggccgacg acggcgtcct
     2521 ggaattcccc ttcgcgcccc gggactggcc ccggcggctg gcgggcaagg aagccatcgc
     2581 cgcctacatg cgccactacc ccgaccacat cgacctgcac gagttcacgg acgtgcgggt
     2641 ccaccggacc gccgagcccg ggaccatcgt cgtcgaaatg cgcggcgtgg gccgcctggt
     2701 ggagaccggc agccccttcg atgcgaacta catcgcggtc gtggccgttc gggacgggct
     2761 catcacctcc tgccgcgact actggaaccc gctcgtcgcc caggagccgg gcgccgactt
     2821 caccaggagc ggccgatgac cgccgccggc accaccctgg tcatcggcgc caacggcacc
     2881 accggcagcc gtaccaccgc gcggctggtc ggcgccggcc accgcgtcaa ggccgcagga
     2941 cgccgcgccg cccgggtccc cggcgcggaa gcggtccgct tcgactggta cgaccccggc
     3001 accttcggcg aggccctcgc cggaaccgac cgcgtctacc tcgtcccgcc gccgggcgac
     3061 ctggacccgg ccgccgtcat gctgcccttc ctccggcagg cccgcggcac cggcgtgcac
     3121 cgcgcggtgc tgctcagctc ctcggccgtg ccggcagggg gcccggcggt gggcgcggtg
     3181 caccgcgccc tgcccggcct gttcgacgcg tgggcggtcc tgcggccctc ctggttcatg
     3241 cagaacttca ccggcacgca cctccacgcc cacagcatca gggacgacgg cgtcatcctg
     3301 accgcggccg ggaccggccg cgtcggcttc gtcgacgccg acgacatcgc cgccgtcgcc
     3361 gtgcacgccc tgaccgatga ccgcgcgccc tgcaccgatc tggtcctgac cggcccggag
     3421 acgctcagtc acgacgacgt cgccacgatc gtcacggagg tcaccggccg gcccgtgacc
     3481 caccgccacc tctccgccga acagctgcgc gaccgcctcg cggcgaccat accgcgggac
     3541 ttcgccgcgc tgctggccga cctggacctg gccatcgccg gcggagccga ggaccgcacc
     3601 accgacaccg tccggcgcct caccggccgc ccgccgcgca gcttcctggc agtcgccgaa
     3661 cgggagttga cgcggagcgg gtgatccgcc cgagacaggc atcaagaacg cgtcaagact
     3721 gccggaatcc ggcaatgcgg gagccccgtt ccggatggga acatgtcatc accagcgagg
     3781 gagcggccac gggggacgag cacggtggac tggtttcccg ttctcggcat gctgcgcgcg
     3841 gcggccgccg gctgagcccc ggggcggggg cccgtgcgag ccccgccccg gccgcgccgg
     3901 acacgacgcg acgcgaaagg acggagacga ccgtgcagtt gcatacccgc acgtggggcg
     3961 agggcgaccg ggtggcgctc ctcgtccacg gcatcatggc cgaccaccgc acctggcggc
     4021 gggtcggccc ggcgctcgcg gaccgcggtt tccgcaccat cgccgtcgac ctgcgcggcc
     4081 acggactcag cgggcgcggc acgtacgccc cggcggactt cgccgacgac ctcgccgaaa
     4141 ccctgcccac cggggccgcc ctcgccctcg ggcactcgct cggcggcctc gccctggcgc
     4201 tggccgcgga acggctgcgc ccggcccgcg ccgtgtacgc cgacccggcc tggcgcctct
     4261 tcgacggccg ccgccacgac ccggtggcgc tgatctccgc caaggacgcc acgcgcgagg
     4321 ccatcgccgc ggggaacccc cggtgggagc ccgccgacgt cgacaccgag gtggcgacgc
     4381 tcgcccggtg ggactcacgc accgcgttcg gcctgagccg gctggcgcac gaggacttca
     4441 ccccggacga cccccgcgtc ccgtccctgg tacagatacc gggcgacggc ggcctggtca
     4501 ccgccgacca cgcggcccgc ctgcggaaac gcggcttcac caccgccacc ctgcccgata
     4561 ccggccacac aatgcaccgc gacgacttcg acgccttcat gaccgccctc gaccactggc
     4621 tcgccggaaa ctgagccccg gccgccgggc agggagcgtt cagatctcct gctcgggcca
     4681 gccgagcagg cgggcgccga tcaccgccgt ctgcaaggtg tagcgctgga gggggtcggc
     4741 cgggtccgcg ccggtcaggc gctggatgcg ggccagccgg taggtcagtg cccgcacgct
     4801 cagcgacatg cggcgcgccg cctccgccgc gacgcagccg gcgtcgaagt acgcgtccag
     4861 cgtgtccacc agcggcgcgg cgccgccgcg cgccgcggcg agcgggccga gcacggaacg
     4921 caccaggtcc gccatggcct gccggtcgcg ggtcagcacc gggaacacca gcagctcggc
     4981 cgcgcgcagc accggcgtgg acagccgcat gcgcgcggcg agttcgagcg cggcgcgcgc
     5041 ctcctcgtag gattcgacga tcccgccggg gccggggcgc gggcggccga gcgcgacccg
     5101 ccactgtccg ggggtgccgt ccgaggccct ggccgtcgtg gcgaagtatt cgccgatttc
     5161 cggcctgctg cccggcgcga tgcacaccag ccgcccgtcc ttcgtggcca gcaggatcag
     5221 ctgttccccg aaccgcccct ccagcgtgtc cgccgcccgc cgcgtcaccg cgtgcgtgtc
     5281 gtcgtacggc tgcgggccgc aggccaccgc caccgaatgg ctgtgcgcca gatgcaggcc
     5341 gaagcgcagc gcgcgggccg acaggtcgcc agggtcgctg cggccgtgca gcaggtcgtc
     5401 gatgaactcg cgcctggccg cctcgtcgcg ccgcaccgcc agcagctggg cccgcccgta
     5461 cccctcggcc agcgcgtcga ccgcctgctc cgccgcggcc agcacgctct ccgcggcgga
     5521 gcggacctgc cgcgcccccg gcgcggcggc cacgcccggc aggtcgcgga acgcggcccg
     5581 cgtggcggcc agatggccgc ggaccagctc gcgcaggccg atcccctcgc gcgcggcccg
     5641 ctcccccagc tcgcggcggc cgcggatctc gtcgcggtcg aggcggcggc cggtccgcga
     5701 gacctcggcc aggatggccg cccagccggc cagataacgg gcccgcaccg ggtcctcgtc
     5761 agcggacacc tcgcgcctcc tcccccgccc gtccccccgc gcccggcccg gcgcgcgtgc
     5821 cgggacagga tacgcagccg ccgccgcggc tacccgacct cggtggtgat ccgttcgtgg
     5881 tcgaagcaca ggaacccgcc cgcgcgggtg gcctcctcca ggggctcggg gtacgaccac
     5941 gccacgtccg cgaccggctc gccgccgccg gtgaacgacc agtagtgcgc ggtgcccttg
     6001 tacgggcaga ccgtgcgggt ggcgctctcc gccagcaggt cgcggcgcac gtcctccggc
     6061 gggacgtacc agcggttggg caggccggtc tccgacagca gcaccggccg cgccgtctcg
     6121 gccagcgtcg tgccgtccag cagcacccgc acggtgctgc cgctgcgccg cgcgtcgacg
     6181 cggtggtacg ggtcgcgcag gtggccgtgg acctcctcct cctcgtcgaa ccacgcgtcg
     6241 gcagcggccc agtacagcgc gtaccagccg gccagccact cggcgcccgc gatgggctcc
     6301 gggtaggccc acacgccgtt cggcacccgc cgcccgcccg cgtcgaccga ccagtacgcg
     6361 gcctggccct tgaacgggca ttcggtggtg tggtcgctcg gccggagcag ctgggtcctg
     6421 acgtcgtccg ccgggacgta cagctgcggc agcaggccgg tttcgtgcag cagccgcccg
     6481 ttgcgggtgt ccagcagcgt ctcgccgccg acgagcgcgc ggacgcgccg cgggaacggg
     6541 tgccagaaca gccggtgggc cgggccggtc agccggtagt tgacggtcgg cggcggcgcc
     6601 gcggacaggg ggccgtggga cagggtcagg gtcatcggaa cgcctttcgc accgggaaac
     6661 ggtctgccat gactgtcgct cccccgttcc cggcccgccg agtcctccca cgcggtgaca
     6721 gcggccgacc gggtgagccc ggccgcccgg atgccctcac ccgacgtcga gtgccgccct
     6781 ggccagttcg aggaaggtca ggtgctcctc gcggaagtcc cggtacgcgg cgtcgaaccg
     6841 ggcgcgctcc gcatcctcgt cgcccgtcgt gagccgggtg agcaggcggc tcgtcgtgat
     6901 cgcccggagg cgcagcgtct gcgcggcccc ggcgaccggc gccggccctt cgagcacgac
     6961 ctcccggctg gctctggtca cctcgttgag cgccgcgcgg ccgtcggccc gcagctgcgc
     7021 gaggacggcg gcccgcggct cgcccggcgg ggcggcgtcc gcctcctcga tgcgccagaa
     7081 gacctccgac agcccgtgcg cggccgcgct catctcccgg taggcgtcgc gccgccggct
     7141 gcgggcctcc gcgacctggg ccgcgtgcgc ggtgacctcg gcctgcaccc gcgcggacct
     7201 ggtggccccc cggccggcga cccagctcgc gaccaccgcc gtcgcgccgg tgatgaggcc
     7261 gatccaccaa ttgctgtccc ccacagggca actatgccag ccgcccccgc atgccccgaa
     7321 cggcccgtca cggaacggcg cgtgccagtg cgtcgacggc ccggtgccag cggtccggca
     7381 ggtccgccag gcccggcagc gccgcgtcgc cgaggaacgt cacgtgcagc cggccgcggt
     7441 acgccgtcca cgcgatgaac agccgggtgc gcggcgagcc gatcggcagc gggtgcagcg
     7501 ccgccgccgg ggtgccgcgg aacgcgagcg gcccgcgggt gcgcacgtcc gccaccgcca
     7561 gcggcacgaa ccgcgcgtcc agccagcggt ccatgccgcg ctgcgccagc cggtgcggca
     7621 gccgcagcag cgccccgtcc tcctgcgcca tctccgccag ccgcgcgaac gccgtgttct
     7681 gcgcgaccag ttggagccga cgcgccgccg agggctcgcc gcagggcagc ggcagcgtcg
     7741 cgcccgcggc ccggttcccc aggcgcggga acggctcggc cggccggcgc gcggtgatcc
     7801 cgagcgacgc gtacaccccg tcctccgggc cggggaagtc cgccgcgtac gcctcccgca
     7861 gcacggccgt cgccgccgcg aggcacacct gcgtgacgcc cgccccggtc gcgcggccga
     7921 tcgcgtacag ccgcggcagc tccgtctcgg cggtgctcgc cgcccgccgg tccgagcgcg
     7981 gcacgtcgag cgcggaccag cgggccctgc ggcgcggcag cggcagcacg tgccgcaggg
     8041 cggccaggcg gcgggccgcc ccgggccctg gcagcgggtc agcgggcgcg gtcggtgcgg
     8101 gccttggctg cctgccgaag agcagctcga cggtgcgggc cacggccaga ccgtcctgga
     8161 acgcgtggtg cgcccggtag cacaggccga agccgcggcc gtcgcggatc acccacacgt
     8221 cccacagcgg gcggtccgcg gccgggggcc gggcgagcag cgcggtgagc atccggtcgg
     8281 cgagcggccc ctcgcccggc ggcaggtcga acgcctgcac gtggcgtgcg gcgtcgaagt
     8341 ccgggtcggc cgcccagtgc gcccgccgtc cggcacccgc cggacggtac gtcagctccg
     8401 gcgcgtgcgg caggcgcccg gcgaggtgcg ccgccacctc ggccaccatg ggggcggggc
     8461 ccgggaacgt cagcagcgcg ccgatctgcc agtcccgttc cccctcgcgg cgcgcgaagt
     8521 ccatgaagat gcggtccagc gtggtctgcg cgaccgttgc ggccggggtg ctcatgatgc
     8581 ctccgcgaaa gccagtgcca cgttgtgccc gccgaagccg gtggacaccg acagggcgag
     8641 cggcagccgc cgcgggcgcg gcgtggtgac caggtccaga tcgatgccgg gcgagggcgc
     8701 ggccaggttg gcggtcggcg ggatcagccg ccgttccacc gcgagcaccg tcagcgcggc
     8761 ctccaccgcg cccgccgcgc ccagcagatg ccccgtcacg gccttggtcg aggtgaccgg
     8821 cggccggtgc ggcagtacct cggcgagcac cccggcctcc acccggtcgc ccagcggggt
     8881 gcccgtgccg tgcgcgttga cgtgggccac gtcggccggc gcggcgcccg ccgcggccag
     8941 cgcctgccgc agggccgcgg cgagaccgcg cccgcccggg tccggcttga cgatgtggtg
     9001 cgcgtccgag gtggcgccct gacccgcgac gcgcgccctg gggcgcgcgc cgcgcgcgcg
     9061 ggcgtcgcgc tcccgttcca gcacgagcat gcccgcgccc tcccccatca cgaagccgtc
     9121 ccggtccgcg tcgaacggcc gcagcgcgcc cgccggatcg ccgaaccggc tggacagggc
     9181 gtgcatccgg tcgaagcccg cctggaagaa cggcgtgagc ggcgcctccg cgccgcccgc
     9241 caccgcgatg tcgcaccggt cgagggccag caggtcgagc gcggtgcaga tcgccgtcgc
     9301 gcccgaggcg cacgcggtgt tgaccgtcag tcctggaccg gtcgcgtgca ggtccatcgc
     9361 cagctgcgcc gcgagcgcgt tgcccagcgc gccgggcacg gagaacgcgg acatgccgtg
     9421 ctgcccggcg tcaagcagca cccggtgctg cgcctcgtag gtctgggcgc cgcagcagcc
     9481 cgcccccgcg acgaccgcga cccgtgcgcc gtcccagccg ccggggtcga gcccggcgtc
     9541 ggccacggcc tcccgggcgg cgagcagcgc cagttgcacg cagcggtccg gcttgcgcgc
     9601 cagcaggccg ttcagccggc cggggccgaa cggcggcacc cggcaggcca ggcgcggcgg
     9661 ctgcccctcg tcgtcgaggg ccgcggtcgg cagtccctgg cagacgcgtt tccacgtggc
     9721 gtcccggccg tcgcccgcgg gcgtcaccgt gccgactccg gtgacgcaca cggcgccgcg
     9781 tccgctcatg cgccggccgc ggcgtgcccg gcgatgatgc cgagcacgtc gcccacggtg
     9841 ccggcctcgt gcagctcctc ctcggtgatg gtcagcccgt gccgctgctt gaggatcagc
     9901 accagctcgg cgatgccgag ggagtccagt cccgcctcct cccggcccgc ctgctcggtg
     9961 atctcctcct cgggcacccc catggagacg agagcggcct tcagatcgtc gaatgacatg
    10021 gcttcctcct gttcctcggg ctgttccgca agctgttcct ggggccgttc cgcgggctgc
    10081 cggcggcgga cccgtggcgc gccgcggcca gatcgcgggc cgcggcgagg ccgccgagcc
    10141 ggtagaccgg gtacagcagc gggacgtcgt agacgaacgg gcgcgggccg agcgcgtccg
    10201 gcggcaccgc ggcctcgggg cccgtcgccg tcagcagccg cacgcccgcg gccagggccg
    10261 ccgcctcccg gcccgccgcg gccagcgcgc cgacggcgta ggcggtgccc agcgggccgg
    10321 ccgcgccctg ccgcaggcac gccgcggcgc gggccatgac gcgcccggtg ccgcccagct
    10381 cgtgggcggc gacggcgcgc gcggcacgca tcacgtgcag cagggggaag gccgcggaac
    10441 gcgtccactc gtacgggtag ccgccgtcga ggcgctgccg cgcggcgagc cagctccagc
    10501 cgcgggccgc ggcggcgcgc tcggccgggc ccggctgccc ggccagcagc gcgagcaccg
    10561 ccttggccgt gatctccgcc tccgaacggg agccgcccgt ataggtgttg aagccgccgt
    10621 ccgcattctg cgcgcggcgc agccaggcgg cgcccgccgc ggcggcgtcc cgggcctggg
    10681 gcgcggcgca gcgccggaga aacgtcacgg ccacggcggt gtcgtcggcg tcggcgtgcg
    10741 tcacgcccgg cgcgtagccc cagccgccgt ccggcagctg ggcgtggcac aggtagtcgg
    10801 ccgaggcggc cagccggtcc tcgcccacgc cgctctccgc gagcgtcagc gaggccaggc
    10861 aggtcagcca gacgtcctgg ctgctgatga acggcacccc gccgtccgcc ctgatctgcg
    10921 ccaccacgaa gtcgacgccg cgcgccacca cgtcgggcgc caggcgccgt tcgcgcagca
    10981 cgagcagaat cgtcacggtg cccagcacgt actggtccca gctgccgtcg caggactggc
    11041 tctcccgcag cagcgcgagg tccgcccgcg ccgccccgca gccgtgccgc ccggtcagca
    11101 gccgcaccgc ggccagggtc ggccgcagcc agccgccgcc gcccgccgcc agcgggtcgg
    11161 gcggcacgtc cggcacgtcc cacgcctcgc cggggcgcag cagggtcagc agcgcgccga
    11221 gcagggcccg cttgcgcagg ctcgcgacgg cgcggtggcc ggccagcgcg gcgcgcagcc
    11281 gcgccgcgcc gcccgacggc tcggggcggc cgagtgcggc ggcggcgagg tagcgggaga
    11341 gcaggcggtc gaacgggtcg gtgtgcgcgg cgggcggcgc ggccagttcg cgggcgcaga
    11401 accgctcgac ggcccgccgc gcgtggggcg cggcgcccgt gtcgcgcagc agccgcacgg
    11461 cgagcgcggc ttcgagcagg cggccgcggc agccgccgcg ccagtgtcct tccggcgcgc
    11521 ggcgggcgag gaggtccgcc gcggcggctt cgacgacggt ggtgagggcc ggcccccggg
    11581 gtccgggggg gcgcggatca cgccgggggg cggggcaacg ggtcgcgggc acgggtgact
    11641 ccacggaacg gcgcggcccg atggaccgcg cagaaggaac aactggcttg gcattccgag
    11701 gagttgagga tgatcacccg ggctgcgcat ccatgagagc acagccgtgg acaccggatg
    11761 gccgacggcc gactattcca ctccataggg tgaacagacc gtcacacagc gcacgcgggg
    11821 atcgttcagg aggcgcggcg cttgccccct ccggcgcggg tgacgcgaaa gacgacgaac
    11881 gccagcaccg cgaggacgac caccacgagc acgactttgg agtagacgga gaccaggtcc
    11941 gtcacccgct cccagtcctc gcccaggcgg tagccggcca gcacgaagag tgtgttccag
    12001 atggcgctgc ccagcgtcgt gagcagcagg aacgtgccca ccggcatgcg ttccacgccc
    12061 gccggaatcg aaatcagact tcggaaaatg ggaatcatcc ggccgaagaa caccgctttc
    12121 gcaccgtgtt tgctgaacca cgcctccgtc ttctcgatat ccgccacttt caccagcgga
    12181 agcttcgccg cgatcgcgat cagccgctcc cggcccagca gcgcacccac ccagtacagc
    12241 gccatcgcgc cgacgaccga cccgatggtg gtccacagca gcgcggccca caggctcatg
    12301 tcgccgcggc tcgcggtgaa gccggccagc ggcaggatca cctcgctggg cagcggcggg
    12361 aacaggtttt ccagagcgat ggccgcaccg gcgcctggcg cgccgagggc ctccatgagg
    12421 tcggtggccc acccggcgat gccgccggga tcttcggagg actcggccag gtgaacggga
    12481 acggaggatg aggtcacacc ccgaacgcta caaagtccct ccgcgccgga acgatggggg
    12541 atgcctcacg ggaaccctgc ggaaaaccgc agtccgccgc cgcgccccgt tcggatagcg
    12601 tcggcggcgt gaagaaagcc ctgcaccgct ggctgcggat ggccaccggg ctcgccatgg
    12661 gcgccgcgac cgtgctgccg gacctcctcg tcctgtacgc cgcgctgctg ctgcggcggc
    12721 ggggcgatcc ggccgcggtg cggctggccg ggtgggaacg cgccagggtg acgcgcctgc
    12781 acggcgacgt cccggaagcc accgcaccac ccgagccgcg cgccgccctg gcctacctgg
    12841 cggcgcgcct gccggtcgga ctgctggccg gtctcgtgct gctctcggcg ctggtcggag
    12901 ccgcctacgc ctcgacgctc gggtggctgt ggttctgggc cgaccacttc tgggccaacg
    12961 ttttctccgg cgtcggcggc ctgttcctgc tcttcctcgc cgcctacgcc gtgcaggccg
    13021 tcgccgccct ggaggccgcc ctcgtgcggc gcttcctcgg ccccacccgg caggaggcgc
    13081 tcgagcggcg catcgaggag ctggcggaga gccgggccgg cgtggtggcc gccgtgcacg
    13141 aggagcgccg ccggatcgaa cgcgatctgc acgacggcgt gcagcagcgc ctggtggcgc
    13201 tcggcatgct gctgggccgc gcccggcgca ggggcgacac cgacgacctg ctggcgcagg
    13261 cccaccagca ggcgcggcag gcgctcgcgg agctgcggga ggtggcctgg cgggtgtacc
    13321 cgacggtgct ggacgaggcc gggctgcggg cggccctcga agcggtcgcc gaacgttccc
    13381 cgctgccggt gcgcctggac taccggctgg cggccgagcc ggaccggccg gtggcggccg
    13441 tcgcctactt cgtggtgtcc gaggccgtca ccaacgccgt gaagcactcg ggcgccgccg
    13501 ccgtcgccgt ccgcctggca ggcgaggggc ccgcgctgac cgtgcgcgtc acggacgacg
    13561 gccggggcgg cgccgacccg gcgggcggcg ggctgctcgg gctggccagg cgcgccgccg
    13621 cgctcgacgg gcggctgtcc gtggccagcc cggccggcgg gcccaccgtg atcaccgcgg
    13681 agctgccgtg cgcgtgatcc tggcggacga ttcgacgctg ctgcgcgagg gcctggtgcg
    13741 gctgctcacc gaggagggcc acgaggtgac cgcggcggtc ggcgacgccg cggcgctgct
    13801 ggccgcggtg gaccgcgatc cgccggacgt caccgtgatc gacgtgcgga tgccgccgac
    13861 gcacagcgac gaagggctgc gcgcggccct cgacatccgc cgccggtggc cggcggtggg
    13921 ggtgctggtg ctgtcgcagt acgtcgaggg ccgctacgcg acggagttgc tgaccgggga
    13981 gccggcgggc gtcggctacc tgctgaagga ccgcgtggtg gagatcgacg agtttctcga
    14041 cgcgctggag cgcgtcgcgg ccggccgtac cgcgttcgac cccgaggtgg tgcggcggct
    14101 gctggcgcgc agttcgcaca ccgatcccct cgcccgcctc acgccgcgcg aacgcgaggt
    14161 gctgcacgag atggcgcagg gccacacgaa cgcgacgatc gccgaacacc tgtgggtctc
    14221 gcgcagcgcg gtggagaagc acgtcaacgc gatcttcgac aagcttcagc tgccaggacc
    14281 cggcggctac agccgccggg tcctggccgt gctgcgctac ctgggctcct gaaggccctg
    14341 gagcccgagc aggaacgact tgactgccgt ggccgcgacc tccccgccgt ccagcgcgtc
    14401 ggggtcggaa cacagcagga ccggccggtc cttctcgtcc tcgggcaggc gaccgtggct
    14461 gccgcggacg cacgacgggt cgagcggcac cacgttcatc cggtagcgca ggcccagctt
    14521 cttgcgggcc agggccgcgg cggccctggc cttggcgaac cggtccgccg ggtcgaagaa
    14581 cagctccgcc gggtcgtagc ccggcttgcg gtggatgtcg acgatggccg cccagtccgg
    14641 cgcggccgcg tcgtccagcc agtagtagta cgtgaaccac gcgccggggt cggccaccgc
    14701 gaccagctcg ccggcgcgcc cgtggtcgag gccgtgccgc ttcttgcccg actcgtccag
    14761 cacctcggcg acaccgggca gcccggccag cacctcacgc gtgcgctcca ggtcctcggg
    14821 gcgccgcacg tacacgtgcg ccacctggtg gtcggcgacg gcgaaggcgc gggacaccca
    14881 cgggtccagg tactccatcc cggcctgcgt gtacacgtcg agcagcccgg cgcggcgcag
    14941 cgcgcggttg atgtcgacgg gccggtccac gggcgtgatg ccgtactcgg acagcaccac
    15001 gaccgtggcg tccgcggcct gcgccgcgtc cagcagcggc ccgatctcgg cgtccagctc
    15061 gcccgcggcg gcccgcgcct gcgggctgtc ggggccgaag cgctggagat cgtagtccag
    15121 gtgcggcagg tagaccagcg tcaggtcggg ccgctgcgtg cgcagcaggt gcctggccgc
    15181 ggcggcgatc cagcgggagg aggcgatgga cgcggtgggc ccccagtagt tgaacagggg
    15241 gaacgggccg tagcggctgg tcagttcgtc gtgcagctcg gacggcctgg tgtagcagtc
    15301 ggggtccttg cggccgtcgg cgtagtagat gggccgcggg gtgatggtga agtcggtgtc
    15361 cgcgcccatc gcgtaccacc agcagacgtt cgcgacggtg tagccgggcc gcacgcggcg
    15421 cgcggcgtcc cagatcttct cgccgccgac gagcgcgttg tgctgccgcc acagcagcac
    15481 gtcgccgacg ccgcggaagt accagccgtt gccgacgatg ccgtgctcgg cgggcggcgc
    15541 gccggtgagg aacgtggcct gcgcggagca ggtcacggcg ggcagcaccg tgccgagcgg
    15601 cgcgcgcgag ccgccgcggg cgagcgcggc gaggcgtggc aggtgatcga gcagggccgg
    15661 ggtgaggccg accacgttca gcacgacgac cgggcgggtc atgacagctc cttgagtccg
    15721 agtccggtca gcaggtcgcg cgcgagggac agttcggcgg cgatgccgtc cgcgagtccc
    15781 tcgggcgtgc ggggccgcag ggccggcggc agtacctgcc aggtgtaggt ctccacctcc
    15841 aggtggcggg tgagggcccg ttcgccgccg accaggcggg tgagggcctg cgtgaggtgc
    15901 ggcagcgtcg aggtcagcgg cgggtgcggg cgggcgtgca gcgggatgtg caggtgaacg
    15961 cgccaggggt cgcgtcccgg cagcggctcg ggcccgaaca gggcgatgtc caggtcgtcg
    16021 tggcccagga cgccgcccgg cgcccgctcc cgcgtctggt gcaggaagcg gggctcggcg
    16081 aagtcggcga gcgccgcgcg caccgcgggc tcccccgggt gctcggcgtg cagggccgcc
    16141 gacagctgcg ccttcacgac gggcacgccg cgcgcggtca gaccggcgat ggcgcggtcc
    16201 gggtcctcga aggcggtggc caggtggcag gtgtccaggc agaccccgac ccggctgctc
    16261 ggcggcgccc cgggcgccgt cagcacctcg gcggcctgcc ccgtggtctc cacgatgcag
    16321 ccgggctcgg gctccagggc gagcctgatg gagcggccgg tgcgctccgc gagtgcgtcg
    16381 agccgtccgg ccagctcggt gaggtgcgcc agcgcccgtt cctggtcctg cggtgtgaac
    16441 ggggtgcgcc aggccagcgg cagcgtcgag atggtgccct ccggctcgtc cccgggcagc
    16501 agctcggcga ggaggccggc caggtcggcg gtgtggtcca ggcgttcgcg gctggtccag
    16561 tcgggcgtgt agacggcgta cttgacgcgt tcgccgccga acccgcggta ggggaagccg
    16621 ttcagcgtga cgacttcgag gccgtggcgc tccagggcct cgcgcagggt gcggcgggcg
    16681 cccgcgtccg ccaccagggt gcgggccgcg tcacgggcca gccacaggcc gatgcccagg
    16741 cgcgcgcggt cgaggcgccg cctgaccggc tcgcagtagt cgcgcagctg cgcgaggacg
    16801 ccgtcgagcg tctccgcggg gtggacgttc gtgcagtagg cgaggtggac gaccgagccg
    16861 tcggggtgct ggaagcgcac ggcgcctcac cgcccggccg gggcgccgcg caggatcgag
    16921 ttgccctcga aactctccgg ctgctcgcgt ccgtccagct caagacggcc gctctggccg
    16981 tagaactcca ccgggttgcg ccacagcacc cggtccacgt cgtcgtcggt gaacccggcg
    17041 gccagcatgg cgtcggcgac gcggcgcgtc ttcagcgggt cgctgcggcc ccagtccgcg
    17101 gccgagttga ccagcatccg gtcgaggccg aggcggcgga gcacctcgac ggtgcgccgc
    17161 tcgtccatct tggtgtccgg gtagacggag aacgccatcc agcagccgct gtccgcggcg
    17221 cggtcgacgg tcgtctcgtt caggtggtcg agcacgacgc gctcgggcgg cagttcggac
    17281 tcggcgagca cggacagggt gcgttccagg cccgcggcct tgtcgcggtg cggcgtgtgg
    17341 acgagggcgg gcaggccgtg gcgcgcggcc agttcgagct gggcggccag cgcgtcgtcc
    17401 tcggccgggg tcagcgagtc gtagccgatc tcgccgacgg ccaccacgtt gtccttctcc
    17461 aggtagcgcg gcagctcctg gagcacgggc gtgcagcgcg ggtcgttcgc ctccttgggg
    17521 ttgagggcga gcgtgcagtg gtgggcgatg ccgtactggg cggcccggta gggctcccag
    17581 ccgagcagcg agtcgaagta gtccaggaag ctggcggtcg aggtgcgggg ctggcccagc
    17641 cagaacgagg gctccacgac ggccgccacc ccggccgcgc gcatccgctc gtagtcgtcg
    17701 gtcgtgcggg aggtcatgtg gatgtgggga tcgaaaatgc gcatcatgcc tccggggcgg
    17761 gcgcgggcgg cggggagagg gccagggcgt gccgcacgtc ggcgggcacg ggccgtccgg
    17821 cggccgtgcg ttccgcggcg aagtcggtga gcatcctggc gagttcgggg tcggcacggt
    17881 cggcgaggcc ggcgacctcg gtcacgggga cgtcggtgaa gacgcacttg aggacggcgt
    17941 gccgccacag gtgctggtcg aggtggcggg cggcgtaggg gccgacggcg gcggcgatca
    18001 gccgcgggtc gttggtgcgc agcgcgtcct cgacgagcgg cagggcgtcg gcgccgaccg
    18061 gcaggtgcgg cagggcgcgc agcacggcgc ggcgctccgc cgcgtcgccg tgccggtaga
    18121 ggcgggcggc ggtggcggcg tcggcgcccg cggcgcgcag cagcgccacc cggacggcgt
    18181 ccgcggcggc gcggccgacg tggcggcccg cggaggtgaa cgcggcctcc caggcgtcgg
    18241 tgcccagcac gccgtccagc caggcgcgag cggcgggggt gaggctggtc tcggtcagca
    18301 cttagccggc ctcccggtgc gcggtggtca ggaagtcgag ggatctgcgg gcgagttcgg
    18361 gtccggcgtg ggagtggcgc ggcagctcga cggagaccag gccgccgtat ccggtggcgg
    18421 cgagggcggc gagcacgggc gggaagttga tctcgccctc gcccagcggc agatgctcgt
    18481 gaacgccgcg ccgcatgtcc tcgatctgca cgtgggcggt ccagggcgcg gcggcggtga
    18541 cgcagtccgg gacgggcacg ggttcgaggc agtggcagtg cccgaggtcg agggtgaggc
    18601 ggacgccgtc gaggtcgcgg cgcagccggt ggaacgcggc gatggtgtcg agcagcatgc
    18661 cgggctccgg ctcgacggcc agcggcaccc cggccgcggt ggcgaggtcg agcaccgggg
    18721 cgagggctcc ggcgagccgc ttccacgcct cggcctccgg agtgtcgcgc ggcacccggc
    18781 cgctgaagca gtgcaccgcg gtcgcgccga ggtcgcggcc gacgcgcacc gcgtcgagga
    18841 gcagcccggt gcggcgctcg cgggcggccg ggtcggggtc gaggaggctg gggccgtgct
    18901 tggcggtggg gtcgagtacg tacctggcgc cggtctcgac cgcgacggcg aggccgaggc
    18961 ggtcgagccg gcgcgcgacc tgcgcggtgc ggcgcccgag atcgggggcg caggggtcga
    19021 ggtgcatgtg gtcgagcgtc agcgccacgc cctggtagcc gaggtcggcc agcagggcga
    19081 gggcgtcgga caggcgcagg tcggtcaggc cgttggtgcc gtaggcgaag cggggccggc
    19141 gtggaccggt catgtggggg tgaccttcct ggacaggcgc cgggcggcgg ccagcgcccc
    19201 gagcagcacg ggcacggcct gcgggcggcc cgcgcgggcg gccagtgccg cctggagcgg
    19261 catcagggcg gtcagcccgc cgacgacgcc ctgccgcacc cgggcgccgg tcggctcgcg
    19321 ggcggcgcgc agcagcgggg gcgcggcggt cagcaggtag gcgaccgaac cggcgaccga
    19381 accggcgcgt tccgcccggg gcgcgggcgt gcgcccgggg gcggcgacgg ccgcggcggt
    19441 gccgagggcg gcggccagcg tgaccagcgg cgcggaccgc ggcccgccga acgcctcgtg
    19501 ccgggagagc gccgtgacgg cggcggtgtg ggcgccgacg acgcccgccg cgggcagcgc
    19561 gcggtggggc gcgcggcccg cgcacgcgcc gaggacgacg ttgagggaac gggccgcgcc
    19621 catcgcggcg ggcccggcag tggtgtgctt gacgcccagg tcgtaggccc aggcggtggc
    19681 ggccagcgcc ccggccgcgg cgagggcggg ccgggagtgg acggcggcga gggtgagccc
    19741 ggcggcggtg agcccggccg ccgccgcgag ggccgcggcc gggcggatgc ggccggaggg
    19801 gagggggcgc gcgggccgtt cgcgcgcgtc ggtgtcgcgg tcggcccagt cgttgagcgc
    19861 catccccgac cagtacaggc acagggagga accggcggcc agggccgtcc gccggagcgg
    19921 cgcgccgccc gcggcggcgg caccggccac gatgtcgccg gggacggtca gcgcggccgg
    19981 gccgcggacc agctcgatcc aggcgcggtt cacggcctgg cccgcagcgt ctgcgcgagg
    20041 gtcagcagct cctcgtactg ctcgccgagc gcggccgggc cggtgtcggg gtccttgaag
    20101 aagaagccga gccccggcac gggcccggac atgccggtgg cgtgggcgcg cgcgaccagg
    20161 cgggccaggt cgagcaccag cggtgcggcg agcgcggagt cgcagccctg ccagatggtc
    20221 tggagcacca tgcgggcgcc gaggaagccg tcgaacgcga cgtggtccca agcggtcttc
    20281 cagtcgccga gcgcgggcac gttgtcgatg tgcacggtgc cctcgggcag gtccccgagg
    20341 gtgtcggcga ggacgcgttc cttccccgcg ttcttggccg cggcggcggc cgggtcggcg
    20401 agggcggcgc cgtcgccgcc gccgagcagg ttggtgccgg accaggaccg cacgtccagg
    20461 gcgcgctggg cgaacatcgg ggccagggcg gcgcgcagca gcgtctggcc ggtcttgccg
    20521 tcccgcccgg cgtgcggcag accggcggcg agggcccgtt cggcgaggcc ggggccgcgc
    20581 atgccggtcg cgggcgtgaa gttgatgtag gagcagccgg cggcgatggc cgcggcggcg
    20641 tagccggtgc tgatcgcggg gtcggtctcg gtgctcgcca cgttgacgac caccgtgcgt
    20701 tccaggccgt ggcggtgggt gaagtcggcg atgtcggcgg ccgggtcggc gcccgggtgc
    20761 ctgatctcgg cgtcggcggc ggccagttcc gcggcgatgg cggcgggcag cccgtgcggc
    20821 aggacgcccg cggcgacgag ctgttccgcg cgtttgggga cggggatgtc gacgatgtcg
    20881 tggccgccga cgaccagccg gtcgaggtcg ggcagcgcgc tgtcggcgaa cggtggcagg
    20941 gcggtgacca tgccggtggg cggggtgagt ccggccgcaa gggcggcccg cccggcgatg
    21001 gtcgtggtgg cgacggagcc gcgcgcgccg atgagccaga ggccgacgcg cgcggtggat
    21061 gcggttgtca cgggggtggc cctcctcctt cgttttcggg tgccacgaaa gggggccccg
    21121 gtgcccggcc gggttcggcg cggtcgggca ccggggggtt gcgacggcgg ggtggggttc
    21181 ggcgtcacca ccgcgccacc gtcaccggcc gtgggggccg ggtccgtcgc cgccgcccct
    21241 cgcggcggag acgggtctag gggacggttc taggggaaac tcgcactgct cagggcagtt
    21301 cctgtatgcg gacgttgcgg aagctaacgg tgtcttcctc accgtggttc tggaggccga
    21361 cgtggccctg cgtcaggcta cgtgcgggat cggtattggt gaagtcgttg atcagggtgc
    21421 cgttgaggaa gatctgaagt cgctcacctt cgacccgcag ttcgtaggtg ttccactccc
    21481 ccggcgggtt gagggccgcg tcgcgggcct cgatgtcggc ggactggaag gtgtagacgg
    21541 acccggtggt gcgttcgggc gcgtccgtgg cgtcgatctg gatctcgtag ccgttgtcca
    21601 cggcggacca cgggtcgtcg gagggcggga ag
//
