LOCUS       NZ_LZNS01000001        24513 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1341354
            Orig. end                         :: 1365867
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24513
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="crocagin"
                     /region_number="11"
                     /rules="(PhyH and Carbam_trans_N)"
                     /tool="antismash"
     cand_cluster    1..24513
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PhyH and Carbam_trans_N)"
                     /kind="single"
                     /product="crocagin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24513
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14513](+)"
                     /cutoff="10000"
                     /detection_rule="(PhyH and Carbam_trans_N)"
                     /neighbourhood="10000"
                     /product="crocagin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14513
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PhyH and Carbam_trans_N)"
                     /neighbourhood="10000"
                     /product="crocagin"
                     /protocluster_number="1"
     gene            complement(425..1561)
                     /gene="glf"
                     /locus_tag="STBA_RS05850"
                     /old_locus_tag="STBA_11940"
     CDS             complement(425..1561)
                     /EC_number="5.4.99.9"
                     /GO_function="GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /gene="glf"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009085867.1"
                     /locus_tag="STBA_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_11940"
                     /product="UDP-galactopyranose mutase"
                     /protein_id="WP_077058220.1"
                     /transl_table=11
                     /translation="MDILVVGAGLFGLTVAERCASELGLRVTVMERRSHLGGNAYSEDD
                     PETGIEVHRYGSHLFHTSNDRVWAYVNRFTEFTDYRHHVYTVHGGKIYSMPINLGTICG
                     FFGRALTPDDARALVREQAAEATDPETLEGKAVSMIGRPLYEAFIRHYTAKQWQTDPRD
                     LPADIIGRLPVRYTFNSRYFSDAHEGLPKDGYGAWLRSMADHRNIEVRLDTDFFEYRKK
                     VPPGVPIVYTGPLDRYFDYVEGELGWRTLDFQTEVRATGDFQGASVVNYADPDVPFTRI
                     HEFRHLHPERDHYPADKTVIMREFSRFAGPSDEPYYPINSRSDRKILSRYRERARAEPD
                     VFFGGRLGAYKYLDMHMAIGSALSLFDNHLLPRFAAVM"
     gene            complement(1587..3482)
                     /locus_tag="STBA_RS05855"
                     /old_locus_tag="STBA_11950"
     CDS             complement(1587..3482)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /locus_tag="STBA_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_11950"
                     /product="glycosyltransferase"
                     /protein_id="WP_077058221.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.5e-06,
                     bitscore: 26.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQYRPPHGLVKQQHVDTVLQRILLPGDHAQRGHVSLLLESTGGA
                     TADFRERMVLPAGHTVSFCSYLNAFPAGYWARWSILDRVRLSLEVVGNAVVRVYRSSAD
                     GEAEVAEEVRHQGQGDVDIELPLTGFDDGGWYWFELSPQKQRNVELLRGSWNALTPAPG
                     RAAAVVGMPTFNRPQDCLATMRVVAGHPALRAVVKRLVVVDQGSDKVTAQPGYQRLADD
                     FGEQLLVVDQPNLGGSGGYAQVMRRALDVPECEQIVFMDDDIVLEPDCLLRGIAFARYA
                     AHPLLVGGQMLNRELPSQLYVMGELIDRRAFTWLKPSHSEYDHDFSTRPLRETPWLHRR
                     IDVSYNSWWTCVIPRTVAEKVGGPLPLFLKWDDVEYGLRSASRGFPTVSVPGIAVWHEP
                     WWKKDEENNWQTYFHSRNRMVAAALHGRLPHFPALFGAHLRDTLRHLVSMQYWNVALRG
                     AGVRDFLQGPDALSSSLPTARQRAARAFERFAPVTGPVEVTETPLGDGAGDLPRQVAQP
                     PGTSGASMFRLLVELVRGCLPVSGGHAGHGHPRLSTDQAAWHVLAALGGAAVTSPDGSH
                     WTLRERRPDVFRKLLAETLISHGRLALAFPRTRSKYRRNRQRLESLRRPSIRKSV"
     gene            complement(3644..5026)
                     /locus_tag="STBA_RS05860"
                     /old_locus_tag="STBA_11960"
     CDS             complement(3644..5026)
                     /GO_function="GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060395.1"
                     /locus_tag="STBA_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_11960"
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="WP_253194555.1"
                     /transl_table=11
                     /translation="MADTNFRGDVLELTRELGATTMRYPGGNFVSSHRWEDGVGPLKDR
                     PRTLDLAWRTVESNAFGLHEFMDWTDRAGVDPYMVVNLGTRGPGEAAALVEYCNVAKGT
                     TLAELRQKNGVDAPFGVQLWGLGNEMDGSWQVGHRSARSYGEVAGQAAQAMKLVDSSIE
                     TVLCGSSNMTMPTYASWEAEALDAAYEHIDYVSLHQYYDPEKYDEQSFLASACSMDRHI
                     EDAIAAVDFVRARQHRQRRIHLAYDEWNVWYQSRFREPYEWSSMSESPRVLIEDDFTVR
                     DAVVAGSLLMTLLRHADRVRIACQAQLVNVIAPIRTFGSGSAWKQPIFYPFALTARHAR
                     GDVLRSELSAPTIDTERFGPVPAVDVVATHDETDGKVAIFAVNRSRQPITLQGATTGFG
                     ELTVTGHHVLADEDTSAVNTPENPLRVRPRDLPVTSAGTGNCRQTLPPVSWNLITLAPA
                     AP"
     misc_feature    5399..5416
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.17"
                     /tool="antismash"
     gene            5474..6463
                     /locus_tag="STBA_RS05865"
                     /old_locus_tag="STBA_11970"
     CDS             5474..6463
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720153.1"
                     /locus_tag="STBA_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_11970"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_253194557.1"
                     /transl_table=11
                     /translation="MAHLAKVSPKTVSNVVNGYVHVSPVTRKRVQRAIQELDFRPNRSA
                     RNLRRGSTGIIGVIVPDLHMSYFAELSHQLLMAAEEHGRTLLIEQTLGDWRREEAVIDH
                     LGDRFVDGVVVTPLAPHGSAFTGRAGMGFVFIGERPSGCSADYVGIDNVAASREAVTHL
                     VDRGRRRIAAIGLQPEPCGGTPLQRHTGYREALAATGLPVDTRLEKETVRYHLHDGARA
                     MRSLLDGPCPPDAVFCFNDALALGALRALHQRGLRVPDDVAVMGFDDFEATEFSTPSLS
                     SVASDKAAMARGAVRLLLERIDSPERPAREILLGHTLRIRESTVGGFS"
     misc_feature    complement(5499..5517)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.93"
                     /tool="antismash"
     misc_feature    5501..5514
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     misc_feature    5660..5662
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5696..5698
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6365..6367
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6576..7811
                     /locus_tag="STBA_RS37070"
                     /old_locus_tag="STBA_11980"
     CDS             6576..7811
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS37070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_11980"
                     /product="hypothetical protein"
                     /protein_id="WP_143659438.1"
                     /transl_table=11
                     /translation="MTLRFSLFMVDSVMSAVPAFIVLWAVSQVADADTYGTVAIGQAFG
                     VIGAIAVIWGWELSGPPKIARADPQARKEYYAESIGARLWLFLPAVSLGMIGLWFATDG
                     SYLAIVPGLAGTLSGLSPSWFYIGTGDSRSLVLLETIPNVAATLLGAFLTVYSGYVLPI
                     LVLPLLGALISPIVASVQILGTRRLCASDFRFANAVAALRKDAAPAATGATTALYVTLP
                     VLLVAAVNHGAVASFAAAERLQRSALSLATPVTKVLQGWVPSTDQRIVVSRIFRALAIG
                     AATSATLATITAFTAAPILRLTTGGEISISVSSSLFLGLIVGAIALSQVTGIVCLASLG
                     IFSKVLTSTILGAIVGLGLVPVIGHSHGTVGALGALALAELTVLLYQLWAVLAALRELR
                     KAPQPELVSVEG"
     misc_feature    6825..6827
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7860..9734)
                     /locus_tag="STBA_RS05875"
                     /old_locus_tag="STBA_11990"
     CDS             complement(7860..9734)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /locus_tag="STBA_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_11990"
                     /product="glycosyltransferase"
                     /protein_id="WP_290443728.1"
                     /transl_table=11
                     /translation="MARTADGAYRSVRKDSWRTVQRTYLPFDRPTETLPLYVSPHTEAP
                     AADGANGGSVSMAAYFSAFPASYWRTWTSCRHVRLKIQVNGACAVTIYASNEHGDAVSV
                     LSRDATNGSSFDEILPLDEFREGGWYWFDVVSPDPDVKIIDAKWQVEDDGAKQGAATIV
                     ITTHDRPETCMDLLEGVGEVIGLGGRVEHIFVVDHGRQYSVADNPRFGELHPEVIRRLR
                     VVKQRNLGGAGGFGRGMHESIKENLSDYVVLMDDDVALDPESFIRGLDFADFCREPTIV
                     GAHMFEMSEPCVLSTFGERVDRRDYMWDSVPGVVDSFDLSLNDLRRTPWLHRRFDVDYN
                     AWWTCLIPADVIRSVGLPLPVFIKWDDIEYGLRAGSHGIPTVSLPGFAVWHESWREKDA
                     HDWQAYYLLRNRCIAALIHSRHRRGTGLVLSNLAFDIESLLCMRYSTAALRRQALIDLH
                     REPTDLLRESDGKLASLISLRQGFLDSSERTDHPEKISIDTTLHLSDRTSPKGKVATVL
                     HMGALICRHAFRRRRHTVAPVLPVVMDEWQHIGHRDAVDIYFPYGNLVSRRRRSRSLFV
                     KSVKGLLKEHVRLWWRWPELARRYQSSASHLVSPDTQGMHLFGEKDSR"
     gene            10001..10840
                     /locus_tag="STBA_RS05880"
                     /old_locus_tag="STBA_12000"
     CDS             10001..10840
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: PhyH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017532.4"
                     /locus_tag="STBA_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12000"
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_077058226.1"
                     /sec_met_domain="PhyH (E-value: 3.2e-18, bitscore: 65.4,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPASAIDLDHVIGRVRTTGYAVLPGVLSSEETRRTREALHRLSEL
                     DDEAHGVERLVGMRERGALRNLAAADDVFHALLETSPALDIVDAFLGRRGILNCFDALT
                     LFPGQGRYPWDYHTDLMDVTGVSFPPDKIPGVNVLYYFDRVREENGATWVVPGSHLTLA
                     DEPDPEVMAPLSVPLEVEPGDGVVFDARIWHCAGTNGSDVPRALIKTLFTAPWYRPQMD
                     FTRAVPEEMLARLGPRARRYLNVHNVPPTTVDELRWRLFHGDAVYEEETAVDKVAEV"
     gene            10842..12086
                     /locus_tag="STBA_RS05885"
                     /old_locus_tag="STBA_12010"
     CDS             10842..12086
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="STBA_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12010"
                     /product="radical SAM protein"
                     /protein_id="WP_077058227.1"
                     /sec_met_domain="PF04055 (E-value: 1.8e-11, bitscore: 43.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5e-17, bitscore: 60.8,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYLLPFFSYRQVDDTVVLTNHITKKQAVDTWATVEALEAIYNSPT
                     DPVRLPAIAEEMELVFADRDEANRWLDTGPSRQTGRLPKIEQIELTNRCPYTCKMCPRT
                     FEMDRGLGDMSLELFDSIMRQVSGDTKFCALHHFGESLLHKGIGEAIAIALGHGVRTGL
                     SCNPPSLLPKRAEAVLTAGIANMVLSLDSLDPEVYKSIRGRAARFDIADRNLRELVRLR
                     NEGGHDTNLTLQMINMHANTDEAEQFLAYCEELGVDRGVVIRLERWDFDDELVAELGEH
                     TSAGYTEPCTRPWNSVAILWDGRVVPCCHDYNGEKVLGDLRHETLEEIWAKPESREFRS
                     RNAEMAICGKCAFGQSFREARRQKEGFHRFHREVTEPSGARWEWFNPSLLDAGRTRAWY
                     DGFDVLPAVPHETGA"
     gene            12089..12517
                     /locus_tag="STBA_RS37075"
                     /old_locus_tag="STBA_12020"
     CDS             12089..12517
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS37075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_12020"
                     /product="hypothetical protein"
                     /protein_id="WP_077058228.1"
                     /transl_table=11
                     /translation="MDETRSTTRDAAVRFESAGPAARAVVLRGWAYADEGLDVAGPLLG
                     AARRSGDQTAARDAWTSAERPDPARALGPVRSVVVLTTAGEATVSIAHGGQAWLPARDE
                     EPPTWTVRLDAGAQVVLDGRAAYRVDAGEATSLLWTAA"
     gene            12534..14513
                     /locus_tag="STBA_RS05895"
                     /old_locus_tag="STBA_12030"
     CDS             12534..14513
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     crocagin: Carbam_trans_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014589.4"
                     /locus_tag="STBA_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12030"
                     /product="carbamoyltransferase C-terminal domain-containing
                     protein"
                     /protein_id="WP_171987652.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 5.3e-41,
                     bitscore: 139.8, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITLGITGSFADLAGTFMPDVPEWLFHDSAAALVVDGTVVAAVEE
                     ERLNRLKHSNLFPASAAKACLELAGVHAEDIDDVAFFFGEDYADLEVGHEYLKFPDVPV
                     LSARELLTTRLTEALGREFRHGDVHFTKHHRAHAFGSFADSGFDSALAVVIDGNGEAEG
                     VSVFDCANGGLKLLHSYPDQHSLGHLYLALLPFLGFRRFDEYKVMGLAPYGAPSVYRDC
                     FRPHYALLDDGGYTMNSGAVVEHLLRAGFEPRRRGEPIRQQDSDLAAALQATLEEVERH
                     LLSHWVRETGAARLCLSGGVAHNSTANGRVLQWGLFDEVFVHPASHDAGASAGAAQHRQ
                     AEVTGGRRGKGLVNAFLGPDLGGRDVVRAELAGWSALVDVEEIAPGEETRYAASAVAAG
                     QVVGWAHGRSEFGPRALGHRSILADPRDAGSRDRVNAMIKKREGFRPFAPAVLAESAGE
                     VFDLTSTKARLDFMGCVVDVRPEWREKLPAVTHVDGSARVQTVHRDTNPVMWELIDGFR
                     AATDVPVVLNTSFNNFAEPIVQSVGDVLRCLVTTTLDLAVVPGHAVRRKPGFRAVLHTA
                     DAVLHPAALLREVATADGSVERVVSFRTQGAKRVALSEPVFGLLRAAASEPTSAAARGL
                     PADEETLDALLLLWEHRVVDFRVR"
     gene            14621..14989
                     /locus_tag="STBA_RS05900"
                     /old_locus_tag="STBA_12040"
     CDS             14621..14989
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013098.4"
                     /locus_tag="STBA_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12040"
                     /product="VOC family protein"
                     /protein_id="WP_077058229.1"
                     /transl_table=11
                     /translation="MTDLRFDSVRLDVRDMDAAEAFYRDALGFERVFRYDLPDGVIQMM
                     APGGRPPGVELTMLRDLTPAASPTEHVAFLADDVPSWVERVRRLGYKVEREPFSVEGET
                     MAFVLDPDGHRIELKHYS"
     gene            complement(14980..15960)
                     /locus_tag="STBA_RS05905"
                     /old_locus_tag="STBA_12050"
     CDS             complement(14980..15960)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019845.4"
                     /locus_tag="STBA_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12050"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_077058230.1"
                     /sec_met_domain="ADH_N (E-value: 1.2e-20, bitscore: 72.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDGFEGTAYTLTSAGEVVGRKRSVPAERTVLRVAAAGVCGTDLI
                     DFRGRVERPGTLPDTSPGHEIAATVVHSDDGWPVGTPVVVDPAFHCGACAPCAAGRTSY
                     CERLLLLGHTYGSGGLARYVAVPGSALLRLPHGIDVVSAALVEPLACAHHAAAKVTCDG
                     PALVLGAGTIGLGVALLLRARGLDVAVVDPSPGRAALAADLGLPVGRPDGALPVVVEAS
                     GTVTGFHDALDAVARGGHVLVAAQHSGTLPVEAGLAFGKELRLGWSLGALRADFHAVLR
                     LLAAGVLDPSPLATPVGPEDFGTATFRDMAAGRTAKPVVVWDAQL"
     gene            complement(15953..16531)
                     /locus_tag="STBA_RS05910"
                     /old_locus_tag="STBA_12060"
     CDS             complement(15953..16531)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_12060"
                     /product="hypothetical protein"
                     /protein_id="WP_077058231.1"
                     /transl_table=11
                     /translation="MLIVFDLMDTLLTDPFLRAHEAACGLTFVEFEAVRPDGVYHRLER
                     GEITEDDYWRSLVDSGLNWDVEEFHRVRREGYAWIDGMRDLVSDCTVANTVVIGSNYAD
                     WIDEVVRDHLHGLDVDVFASCRLGVRKPSPRFFELVADATDTPLREMLLVDDKRVNTEA
                     MAALGGIGVHFTDGTDARQALRKAGVAGV"
     gene            complement(16540..17652)
                     /locus_tag="STBA_RS05915"
                     /old_locus_tag="STBA_12070"
     CDS             complement(16540..17652)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019845.4"
                     /locus_tag="STBA_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12070"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_171987653.1"
                     /sec_met_domain="ADH_N (E-value: 7e-15, bitscore: 53.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGRRVVRVPGANGTWWPRLVHGPVPPRPGPQWRLVRVTTAGICG
                     SDLRGLAQAPVHGAADPAGVVPGHEVVGVLADGPGSGERVVVHPLVTCAARDEPLCASC
                     RNGRFGQCDSFWQPTVRWSKSLGFSTDLGGGWADWVWAHRDMVRTLPPDLPDRTAVLAE
                     PLSVAISGVRSVRDHAGDDVVIVGGGTLGLLTVVAVASVLPGSRCFAVVRHDFQADAAR
                     ALGAEPVRTPADLPGARPRGAEVLIDGPGLAVDAGGTSSSLIAAMRAVRAGGRVLTLGN
                     PDDCTDLSPLWLKGLTLLGHLEHAAEPSPRPPESADSLDEAVRLLGAAPDLGRLLVTHT
                     FATDDVARALAVARARRTHRAIKVILQPPS"
     gene            complement(17649..18617)
                     /locus_tag="STBA_RS05920"
                     /old_locus_tag="STBA_12080"
     CDS             complement(17649..18617)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (64-223). E-value:
                     1.2e-08. Score: 26.3. Matches aSDomain:
                     nrpspksdomains_STBA_RS05920_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013530.4"
                     /locus_tag="STBA_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12080"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_077058233.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 8.2e-13, bitscore:
                     46.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGEVLVTGAAGFIGSHLARACRRSGFTVTALDPAPDGERRSAVG
                     GVVRATAGDAGLLADVQAGRYRAVLHQGGISSTLETDRDLLRAVNVDEPLALAEACAVS
                     GTRFAYASSHSVYGTIRGRFAVAEEDVADRDRCTGPLNDYAWSKLTLDQEMAARFGDDA
                     PWSGYRYTNVFGTGEEHKGSMASIISQLLRQTATGVPLKLFADTLEACRDYVPVETVAD
                     TLLDVIRQPPPPGVYNLGSGVPVSFATLLGWCGELRGEEGLAVRLVPNPMSSRYQYWTC
                     ADQSRAGGVLPRARGLSAEEVRSAAHRLYRGFADATAQPVP"
     aSDomain        complement(17949..18425)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STBA_RS05920_NAD_binding_4.1"
                     /evalue="1.20E-08"
                     /label="STBA_RS05920_NAD_binding_4.1"
                     /locus_tag="STBA_RS05920"
                     /protein_end="223"
                     /protein_start="64"
                     /score="26.3"
                     /tool="antismash"
                     /translation="RYRAVLHQGGISSTLETDRDLLRAVNVDEPLALAEACAVSGTRFA
                     YASSHSVYGTIRGRFAVAEEDVADRDRCTGPLNDYAWSKLTLDQEMAARFGDDAPWSGY
                     RYTNVFGTGEEHKGSMASIISQLLRQTATGVPLKLFADTLEACRDYVPVETVADT"
     gene            complement(18614..19831)
                     /locus_tag="STBA_RS05925"
                     /old_locus_tag="STBA_12090"
     CDS             complement(18614..19831)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013227.4"
                     /locus_tag="STBA_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12090"
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="WP_077058234.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-87,
                     bitscore: 293.3, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGPGWYLIDDAEEREVVEALREGHLSRYRFGDESAVSKTMRFER
                     EMAALLGSPHALAVNSCTSALVAGLTGLGVGPGDEVIVPGYTFIASIAAVLFTGARPVL
                     AEIDESLTLAPDDVAAKLGPRTKAIMPVHMMGAPADLDRLLAVADGIPLLEDCAQACGG
                     SYRGRRLGTIGAAGAFSFNTGKTMTTGDGGLLVTESPEVYRQAFAFHDHGFAPDRAGLV
                     EDGPRMGLNLRMHELAAALGLAQVRKLDRALEHCRELAAVVREGLDGVPGVGHRVIHDE
                     GWCGTAHVLIFEEPARATAFARELGGSTLDTSTKHNYARAGQLHVEFTRTDANGERRIR
                     NAAPGDLPRTDALLSRSVALSVGVVDGYLGTLGEVTVRDTAQEAAAKTAKVREALLRTA
                     SPEATG"
     misc_feature    complement(19769..19771)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19908..21392)
                     /gene="rfaE2"
                     /locus_tag="STBA_RS05930"
                     /old_locus_tag="STBA_12100"
     CDS             complement(19908..21392)
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rfaE2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012515.4"
                     /locus_tag="STBA_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12100"
                     /product="D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase"
                     /protein_id="WP_366510920.1"
                     /sec_met_domain="CTP_transf_like (E-value: 3.3e-14,
                     bitscore: 52.0, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVLCAEVDVALGASSRAPGKHGNAPAPLVVVGDALLDHDIVGVV
                     RRLSPEAPVPTVDNAQARTRPGGAGLAALLAARQDRPVVLITALSVDQEGGELADLLRS
                     HDVHVIDLGADGTTPVKSRVRTEDRSLLMLSRASDRRSRSRRRLTGDERDLLLGAAAVL
                     VSDYGNGVTFDESVREALTAAAPRIPVVWDPHPRGAEPVSGVRLVIPNSREAAHFAGGT
                     GTGLVGDIDRAGTLLDRWQTGGVVITRGGNGAVLLESRDGAPLVVPGVPVAAADTCGAG
                     DRFAVTVASLLADRALLAEAVTAAVGTATEFVAAGGASALVADAAAEPARQGGTEHGTT
                     GNDLAALLARVRGRGEEVVAAGGCFDLIHPGHIALLDQARRLGGCLVVCLNDDDSVRRL
                     KGETRPVVPQRDRAAVLASLSSVDAVVLFGEDTPAEVLKAIRPDIYVKGGDYRVEDVAE
                     AALVAEWGGRTVIVPYVEGRSTTGMISRIHDSGSRV"
     gene            complement(<21378..>21830)
                     /locus_tag="STBA_RS38670"
                     /pseudo=""
     CDS             complement(<21378..21830)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525592.1"
                     /locus_tag="STBA_RS38670"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="SIS domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="SIS_2 (E-value: 3.3e-22, bitscore: 77.7,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRSLADVLGGGGRLLAAGNGGSAAEAQHLTSELVGKLRDEREPL
                     SAIALHAETSSVTAIGNDYGFDEVFARQVRAHGRPGDVLMLLSTSGRSENLLCAARAAR
                     EAGLTVWGLSGPEPNPLAELCDETLAVQAEGTATIQECHLVAVHVLC"
     gene            complement(21911..22399)
                     /locus_tag="STBA_RS05935"
                     /old_locus_tag="STBA_12110"
     CDS             complement(21911..22399)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013756.4"
                     /locus_tag="STBA_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_12110"
                     /product="flavin reductase family protein"
                     /protein_id="WP_077058236.1"
                     /transl_table=11
                     /translation="MIGGSLLDTLLTSCVVVTSRDGDEPRGCLVGSVMPVGYDAGVVAF
                     ALTAGSRTERAVAGSGVAALHVLAADDLATARVFAADVDRFGTVPWSPGVLGAPVLGGV
                     AGVLEMAVTASCAAGGCRVFCGEVRHATSTGTPGRVLTITEIRERGVESSRTSMGEGT"
     gene            complement(22396..23394)
                     /locus_tag="STBA_RS05940"
                     /old_locus_tag="STBA_12120"
     CDS             complement(22396..23394)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_12120"
                     /product="hypothetical protein"
                     /protein_id="WP_077058237.1"
                     /transl_table=11
                     /translation="MDRTYEEEIATLGATWRAWQRWRGEAGPGAVTGLGGPAAFVASGG
                     SLAVAHLAAAVYERRYRQPAAVLTPVEFALSPVEFGTVVVISDSMSHPDARLAADHAAA
                     GRACAVVLSNRPAEELRDRLGDRLAIVSAPRPGRDGWIATNSVLSLSLGALTLLGADEG
                     APDPDEVVARWVVGGLLRADADLTRPRLLCLHTPGLRNVAVDLETRAMEAGLGVVTISD
                     LRNLGHGRHVGLYRNAGSTSVLVLAERRWAPLVEGTVDSLPPGVEATVWQAGCDDVWAP
                     VELLVPSAAFLASRAAEAGVDPGNPEVWPGGKALFRTRVADVVPDVLGERG"
     gene            complement(23500..24405)
                     /locus_tag="STBA_RS05945"
                     /old_locus_tag="STBA_12130"
     CDS             complement(23500..24405)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_12130"
                     /product="hypothetical protein"
                     /protein_id="WP_077058238.1"
                     /transl_table=11
                     /translation="MTGTATGAGIADTAAVTYFRLRRELVSPGCERLVVPADAGTPFWA
                     WYAEWQRGGAVRVEAGPPAGLAFPEPTGEVAQWCSGGLASAYTDLLVSHLSPTPLSYRS
                     FAAEVEPHRAGAPLLFTLAVLSAHRGAACSYAGIARRAALAAPAGPSGPADIDADLEFL
                     ARWNEFHPALRLRTVCGELTRERMLASLPPGAEHRLEGCRRTAAAPWCGDCAMCFDTFY
                     AAKAVGRPLGFRLSRRIFEERYTRDYRTWLNTEFRGVQDGGLQLLARLQITHGLQVDPS
                     TDIDHRQEKPAGTHHEEQQT"
ORIGIN
        1 ccagggaggg catcacatag atattcccgc tcgccaccgt ctcaacggcc cggatcatct
       61 cgaccgaatc ggcgtcgctc gcgacgacac cccggacgcc ggcctcgagg agagcgttcg
      121 tcgcggcggc ggtcgtctcg tgggagacca ccagcaccgg tgggcaggtc tcgcttccgg
      181 cccggagcca gggcgtcatt tcgcccggct cacgggtggt tgccgaaagg tcggcgacga
      241 cgaggtcgga gtgcgtcgtc cgccgggccg cgaagcagtc gcggggatct gtcacgacct
      301 ccaccaccga cacgcgcggc gccgcactca gcatggtgcg cagcccttcg cgggtaatcg
      361 cgagcgatgc acagacaacg acctcaatac tcatttgact ctccactcga cgactgccag
      421 agcgtcacat cactgcggcg aagcgcggca gcaggtggtt gtcgaagagg ctcagcgccg
      481 aaccgatggc catatgcatg tcgagatact tataggcgcc gaggcgtccc ccgaaaaaca
      541 cgtcgggttc ggctcgggcc cgctcccggt aacgggacag gatcttccgg tcgctccgtg
      601 aattgatggg gtagtagggc tcgtccgaag ggccggcgaa ccttgagaac tcgcgcatga
      661 tgaccgtctt gtcggcaggg tagtgatccc gctccggatg caggtgtctg aattcgtgga
      721 tccgagtgaa cggaacgtcc gggtccgcgt agttcacgac ggatgcgccc tggaagtcac
      781 ccgttgcccg cacctcggtc tggaagtcaa gggtgcgcca ccccaactca ccttccacat
      841 agtcgaaata ccggtccaag ggacccgtgt acacgatggg aacgccgggc ggtacctttt
      901 tccggtactc gaagaaatcg gtgtcgagcc gcacctcgat gttccggtgg tcggccatgg
      961 accgcagcca cgcgccgtac ccgtccttcg gcaacccctc gtgcgcatcg gaaaaatacc
     1021 tgctgttgaa tgtgtagcgc accgggagcc tgccgatgat atcggcaggg aggtctcgcg
     1081 ggtccgtctg ccactgcttc gccgtatagt gccggatgaa cgcctcgtag agcgggcgtc
     1141 cgatcatcga gacggccttg ccctcaagcg tttccggatc ggtcgcctcg gccgcctgtt
     1201 cccgcaccag ggcccgtgca tcgtccggtg tcagcgctct gccgaagaaa ccgcagatgg
     1261 tgccgagatt gatcggcatg gagtagatct ttccgccgtg caccgtgtac acgtgatgcc
     1321 ggtaatcggt gaactcggtg aagcggttca catacgccca taccctgtcg ttggacgtat
     1381 ggaagaggtg ggacccgtag cgatgcacct ctattccggt ttccggatcg tcctcgctgt
     1441 acgcgttgcc tccgagatgg gaacggcgct ccatgaccgt gacgcgaagc ccgagctcgg
     1501 aagcacatcg ctcggcgacg gtgaggccga acagtccggc tccgacaacg agtatgtcca
     1561 tctcgacgat ccattcatcc gtgcgatcaa actgatttac gaattgaggg ccggcgcagc
     1621 gactcaagtc gttggcgatt tcgtcggtac ttcgatctcg tccggggaaa cgcgagggcg
     1681 agcctgccgt ggctgatcag cgtctcggcc agaagtttcc ggaagacatc cggtcgacgt
     1741 tctctgaggg tccagtggct tccgtccggg ctggtgacgg ccgcgccacc gagagcggcc
     1801 agaacgtgcc acgcggcctg gtcggtggac aagcgggggt gcccatggcc ggcatgtccg
     1861 ccggagacag gaagacaacc ccggacaagt tccaccaaga ggcggaacat ggacgctccg
     1921 gaggttccgg gcggttgtgc cacctgccgg ggaagatctc cggcgccgtc ccccaggggg
     1981 gtctcggtga cctcgaccgg tcctgtcacc ggcgcgaagc gctcgaacgc ccgcgctgcc
     2041 cgctgcctgg cggtcggcag agacgacgac agagcgtcgg ggccctgcag gaagtcccgg
     2101 actccggcgc cgcgcagggc gacgttccag tactgcatgc tcacgaggtg gcggagggtg
     2161 tccctcagat gagcaccgaa gagagcgggg aaatgcggca accgtccgtg cagcgcggcc
     2221 gccaccatcc tgttgcggct gtggaagtac gtctgccagt tgttctcctc gtccttcttc
     2281 caccaaggct cgtgccagac cgcgatgccg gggacggata cggtggggaa tccccggctc
     2341 gcggaccgca gtccgtattc cacgtcgtcc cacttcagga acagcggcag tggcccgccg
     2401 accttctccg ccaccgttct ggggatgacg caggtccacc agctgttgta ggagacgtcg
     2461 atgcgccggt gcagccacgg tgtttcacgg agtgggcggg tcgagaagtc gtggtcgtac
     2521 tccgaatgcg acggcttcag ccaggtgaaa gcacgccggt cgatgagttc tcccatgaca
     2581 tagagctgtg acggcagttc ccgattcagc atctgtccac cgacgagcag cgggtgcgcc
     2641 gcgtagcgcg cgaacgcgat gccgcgcagc agacagtccg gctccaaaac gatgtcgtcg
     2701 tccatgaaga cgatctgctc gcactcgggt acgtccagcg cgcgccgcat cacctgtgca
     2761 tatcctccgc tgccgccgag gttgggctgg tcgaccacga gaagctgctc gccgaagtcg
     2821 tccgccaggc gttggtaccc cggctgtgcg gtgaccttgt cgctgccctg gtccaccacc
     2881 accagtcgct tgaccacagc gcgcagcgcc ggatggccgg ccaccacccg catggttgcc
     2941 aggcagtcct gcgggcggtt gaaggtcggc attccgacga cggcagcggc ccggcccggt
     3001 gcgggcgtga gggcattcca cgagccccgg aggagttcca cgttccgctg cttctgcggg
     3061 gacaattcga accagtacca gccgccgtcg tcgaaaccgg tcagcggcag ctcgatgtcg
     3121 acatcgcctt gaccttgatg ccggacctcc tccgcgactt cggcctcgcc gtcggcggag
     3181 gaacggtaca ccctgaccac tgcgttcccc accacctcca gactgaggcg tacccgatcc
     3241 agaatcgacc agcgggccca gtagcccgcg gggaacgcgt tgagatagct gcagaaggac
     3301 accgtgtggc cggctgggag gaccatcctc tcgcggaagt cggcagtggc acctcctgtg
     3361 gattccagca gcagggacac atgcccccgt tgtgcgtgat cgccgggcag cagtatccgt
     3421 tgcagcacgg tgtcgacatg ctgttgcttc acgagaccgt ggggcgggcg atactgatcc
     3481 atgtccccgt cctccctacg ttgatgtcct gcagcggact ttcggcccga gccgtcgagg
     3541 gccgcagccg tgctcgcact cgcccgccgg tgctacgacc ccggtccgtc gcttggcatc
     3601 gccccggcag gcgcgcacgg cgtacccggc acacgacgcc ggctcatgga gcggctggag
     3661 cgagggtgat gaggttccag gagacaggag ggagagtctg tcggcagttg cccgtcccgg
     3721 ccgaggtgac cgggaggtcc cggggtcgca cacggagagg attctcagga gtgttgacgg
     3781 ccgaggtgtc ctcgtccgcc agcacgtggt gaccggtgac ggtcagctca ccgaagccgg
     3841 tggttgcgcc ctggagagtg atgggctgcc gacttctgtt gacggcgaag atcgcgactt
     3901 tgccgtcggt ctcgtcgtgc gtcgccacca cgtccacggc ggggacgggt ccgaatctct
     3961 ccgtatcgat cgtcggagcg ctgagttcgg acctcagcac gtcgccacgg gcgtggcggg
     4021 cggtgagggc gaagggatag aagatcggct gtttccaggc ggacccggag ccgaaggtcc
     4081 tgatcggcgc gatgacgttg acgagttgag cctggcaggc gatgcggacc cggtccgcat
     4141 gacggagcag tgtcatcagc agactgcccg cgacgacagc gtccctgacg gtgaagtcgt
     4201 cctcgatgag gacgcggggg ctttcggaca tcgacgacca ctcgtacggc tcccggaacc
     4261 gggactgata ccacacattc cactcgtcgt acgccagatg gatgcggcgc tgccggtgct
     4321 ggcgtgcccg cacgaagtcc accgccgcga tggcgtcctc gatgtgccgg tccatggagc
     4381 atgcggatgc cagaaaggac tgttcgtcgt acttctcggg gtcgtagtac tggtgcagtg
     4441 acacgtagtc gatgtgctcg taggctgcgt ccagggcttc ggcttcccag ctcgcgtacg
     4501 tcggcatcgt catgttggag ctgccgcaca gcaccgtctc gatgctgctg tccacgagct
     4561 tcatggcctg ggccgcctgg ccggccacct caccgtacga acgcgcgctg cggtgtccga
     4621 cctgccagga gccgtccatc tcgttaccga gaccccacag ctgcaccccg aagggggcgt
     4681 ccacgccgtt tttctgacgg agctcggcca gtgtggttcc cttcgccacg ttgcagtact
     4741 ccacgagagc ggctgcttcg ccggggcccc gggtgcccag attgaccacc atgtacgggt
     4801 ccaccccggc gcggtccgtc cagtccatga actcgtgcag accgaatgcg ttgctctcca
     4861 cggtgcgcca ggcgaggtcg agcgtacgag gacgatcctt cagtggaccg acgccatctt
     4921 cccagcggtg gctggagacg aagttcccgc cgggatagcg catcgtggtg gccccgagtt
     4981 cccgggtcag ctccagcaca tcgccacgga agttcgtgtc agccaccgtc gaagggtgtc
     5041 cagggtcgta cacaccgccg tagacaccac ggcccatgtg ctcgacgaag aatccgaaga
     5101 ggcggcggtc gattgcaccg atgcggaagt ccctatcgac tcgtacggtc gccgttgtca
     5161 tgactgtcca ttcgcgtcga accgagccgg ccatatgaga tggacgtgcc agcgagttta
     5221 gcttcctgcg cacagccaag tcgtcgcagt gtctacctgg ttcaaaggat tcgcagtaag
     5281 tgtcactttc gtccatagct gatctacttc aggatgctgc acgaccacaa cctgacggaa
     5341 gggtgatggt gtgtccgcca cgcacggtag ggtgtccagc gggccctggg accggggttt
     5401 gtcagcatcg tgtgatccag gagggggagg cgtgacgtca cacggtcgcg cgagaagtgt
     5461 caccatcaag gacgtggcgc accttgccaa ggtttccccg aagaccgtat ccaacgtggt
     5521 caacgggtac gtgcacgtga gtcctgtgac gaggaaacgg gttcagcggg ccatccagga
     5581 gctcgacttt cgaccgaaca gatcggcccg aaatctacgc cgcggcagta caggcatcat
     5641 cggcgtcatc gtgcccgact tacatatgtc ctacttcgcc gagctcagcc atcagttact
     5701 catggcggcc gaggagcacg gccgtacctt gctcatcgag cagactctgg gggactggcg
     5761 gcgggaagaa gcggtcatcg accatctcgg cgaccggttc gtcgacgggg tggtggtgac
     5821 cccgctcgct ccgcacggca gtgcgtttac cgggcgcgcg ggcatggggt tcgtcttcat
     5881 cggggaacga cccagcggat gttccgccga ctatgtgggt atcgacaatg tcgccgcctc
     5941 ccgggaagcc gtcacgcacc ttgtagaccg tggccggcgg cgcatcgcgg ccatcggcct
     6001 ccagcccgag ccgtgcggcg gcacaccact gcagcgacac acgggttacc gcgaagcgct
     6061 tgcagcgacc gggctgccgg tggacacgcg actggagaag gaaaccgtcc gttaccacct
     6121 gcacgacggg gcacgggcga tgcgctcact gctggacggg ccgtgtccgc cggacgccgt
     6181 gttctgcttc aacgatgctc tggctctggg cgcactgcgg gctctgcacc aacgtggact
     6241 gcgggtcccc gacgatgtcg cggtcatggg tttcgacgac ttcgaggcga ccgaattcag
     6301 cacaccgagc ctgagcagcg tcgcctcgga caaagccgcc atggcccgtg gcgcggtgcg
     6361 tctgttactg gaacggatcg actctcctga gcggccggcc agagagattc tgctgggaca
     6421 caccctgcgg atccgcgagt ccacggtggg cggattctcc tagcagctgt ccgggcgagc
     6481 atgtcctgtt cgaacgtgtc gccgagtcgg cagctgacac caccagtcga accaggaggc
     6541 ttgtcatagg cgctaatcag agcaccatca cggtaatgac cttgcggttt tcgctattca
     6601 tggtcgattc agtcatgtcc gcagtccccg ctttcatcgt gctgtgggca gtttcccagg
     6661 tcgccgatgc ggacacatac ggaactgtcg ccatcggaca ggcctttgga gtgatcgggg
     6721 caatcgccgt catttgggga tgggagcttt ccggaccacc aaaaattgcc cgagcagacc
     6781 cacaggcacg caaagaatat tacgccgagt cgatcggcgc acggttatgg ctgttccttc
     6841 ctgccgtgtc tctcggaatg atcggcctgt ggttcgccac cgatggctcc tacctggcaa
     6901 tcgtgccggg tctggccgga acactttccg ggctatcacc ttcctggttc tatatcggaa
     6961 caggtgacag tcgatccctg gttcttctcg aaaccattcc gaatgtagcg gcaacattgc
     7021 tgggcgcttt cctcacggtg tattccggat atgtgctgcc gattctggtg ctgccgctgc
     7081 tgggcgcgct gatcagtccc attgtcgcct cggtgcagat cctgggcacg cgccggctct
     7141 gtgccagcga cttccgattc gccaatgcag tggcggccct gcggaaagat gctgctcccg
     7201 ccgccacggg tgccacgaca gcactgtatg tgactctccc cgtgctcctg gtggcagcgg
     7261 tgaaccacgg cgcggtcgcg tccttcgccg cagcggaacg cctccagcgg tccgcgctct
     7321 ctctggcgac gccggtcaca aaagttttgc agggctgggt gccctcgaca gatcagcgaa
     7381 tcgtagtatc cagaatcttt cgggcactgg ccatcggggc ggcgacctcg gccacattgg
     7441 cgaccattac cgctttcacc gccgcaccaa ttcttcgcct caccacgggc ggcgaaatct
     7501 cgatttcggt ttcctcttcg ctttttctgg gcctcatcgt cggcgccatc gccctctcac
     7561 aagtcacggg tatcgtgtgc ctggccagcc tcggtatctt ttccaaagtt ctgaccagta
     7621 ccatcctcgg cgccatcgtc ggcctgggac tcgtgcccgt gatcggccac agtcacggca
     7681 ctgttggcgc cctgggagct ttggcgcttg cggagctgac cgtgctcctc taccagctct
     7741 gggccgtgct ggcagcgcta cgcgaactca ggaaggcgcc gcagcccgaa ctcgtgagtg
     7801 tggagggctg acctccgccc tccagctcgc ggcacctcgc accgccattc ggccaaaggt
     7861 cagcgggaat ccttctcacc gaaaaggtgc attccctgtg tgtccggcga gaccaggtgg
     7921 ctcgctgacg actggtacct gcgagccaat tcgggccatc tccaccagag ccggacatgc
     7981 tccttgagca aacccttgac ggacttcacg aagagcgaac ggcttcgcct ccgacgggaa
     8041 acgaggttcc catagggaaa gtagatatcg accgcatcac gatggccgat atgctgccat
     8101 tcatccatca ccacagggag taccggagca acagtatgcc gacgcctcct gaacgcgtgc
     8161 cggcatatga gcgcgcccat atgcaggacg gtggcgacct tacctttcgg cgacgtacga
     8221 tcactcaggt gcagtgtcgt gtcgattgaa atcttctcag ggtggtcagt ccgttccgag
     8281 gaatcgagaa aaccctggcg caggctgatc aatgacgcga gcttgccatc ggactcgcgg
     8341 agcagatctg tcggctcccg gtgcaggtcg atcagcgctt gacgcctaag agcagcagtt
     8401 gagtaccgca tacacaacag cgattcgata tcaaaggcga ggttggacag gacgagcccg
     8461 gtgcctcggc gatggcgcga gtggatcaac gcagcgatac atcgattacg caaaagataa
     8521 taggcttgcc aatcatgggc gtctttctcc ctccaggatt cgtgccagac cgcgaatccc
     8581 gggagactga ccgtggggat gccatgcgag ccggcccgga gtccgtactc gatgtcgtcc
     8641 cacttgatga agacaggcag cggaagtccc acggacctta tgacgtcggc cggaatgaga
     8701 catgtccacc aggcattgta gtcgacatcg aaacgccgat ggagccaggg agttctgcgc
     8761 aggtcattga gcgacaagtc gaatgaatcg acgactccgg gcaccgaatc ccacatgtag
     8821 tcccgccggt ccaccctctc gccgaacgtg gacagtacac acggttcact catctcgaac
     8881 atgtgggccc ccacgatagt gggttcccga cagaaatcgg caaaatccaa gcctctgatg
     8941 aagctttccg gatccaaggc cacgtcatcg tccatgagca cgacgtaatc actcagattt
     9001 tccttgatgg attcgtgcat accacgcccg aaccctccgg ctccgccaag gtttcgctgc
     9061 ttcacgacac gcagccggcg gatcacttcc ggatgcagtt caccgaatcg cggattgtcc
     9121 gcgaccgagt actgccggcc gtgatcgacg acgaatatgt gctccaccct cccgccgagg
     9181 ccgatcacct caccgacccc ctccaggagg tccatacagg tttccgggcg atcatgcgtc
     9241 gtgatcacga tcgtcgcggc gccctgcttt gcgccgtcgt cctccacctg ccatttggca
     9301 tcgattattt tcacatccgg atcaggcgaa acgacatcga accaatacca cccaccctcc
     9361 cgaaactcat ccaatggcaa aatctcgtcg aacgaactgc cgttcgttgc atccctggac
     9421 agaactgaca ccgcgtcacc gtgctcgttc gacgcataaa tcgtcaccgc acaagcgcca
     9481 ttcacctgga ttttcaacct gacgtgacga cacgatgtcc aggtacgcca ataactggcc
     9541 gggaaagcgc tgaaataggc tgccatggat acactgccgc cgttcgcccc gtccgccgcc
     9601 ggggcttcgg tgtgagggga aacgtagagc ggcaaggttt ccgttggccg atcgaaaggg
     9661 aggtatgtcc gctgaacggt tcgccaagaa tccttccgga cgctccgata cgcaccatcg
     9721 gctgtcctcg ccactttgca gctccttcga agatggcgtt ccgctcaaac gatctgggcc
     9781 tcggcacaga cctgtcaatg gtggcgacca catccggttc ggccccgcgc ggtcggcggc
     9841 ttccccgccc gcgcactccc ccgccgcgcc cctggacagc ttgtggtcgt gcagcatcgt
     9901 gacgatcgcg aaccgtggac gggtaccacc ggctgctgaa aactcgacgt gcagtgtcgc
     9961 aacaggacga cgaagcgcgt accacgaggg gagaaggcca ttgcctgcca gtgcgatcga
    10021 cctcgaccac gtgatcggca gggtacggac gacggggtat gcggtgcttc cgggcgtcct
    10081 ctcgtccgag gagacccggc gaaccagaga ggcactgcac cggctgtcgg agctggacga
    10141 cgaggcccac ggcgtcgagc gcctcgtcgg gatgcgggaa cgcggcgcgc tgcgcaacct
    10201 ggccgccgcc gacgacgtct tccacgctct gctggagacc tcgcccgcgc tcgacatcgt
    10261 cgacgccttc ctgggccgac ggggaatact caactgcttc gacgccctga ccctgttccc
    10321 cgggcagggc cgctacccgt gggactacca cacggacctg atggacgtga ccggtgtgtc
    10381 gttcccgccc gataagatcc ccggtgtcaa cgtcctttat tacttcgacc gggtgcgcga
    10441 ggagaacggc gccacctggg tcgttcccgg gagccacctc accctcgccg acgagccgga
    10501 ccccgaggtg atggcgccgc tgtcagtgcc gctggaggtc gagcccggtg acggcgtcgt
    10561 gttcgatgcg cgcatctggc actgtgcggg taccaacggc tcggacgtac cacgcgccct
    10621 gatcaaaacg ttgttcaccg cgccctggta ccggccgcag atggacttca cccgtgccgt
    10681 gcccgaggaa atgctcgccc ggctcggccc gcgcgcgcgc cgctatctga acgtgcacaa
    10741 cgtaccgccc acgaccgtcg acgagctgcg gtggcggctg ttccacggtg acgcggtgta
    10801 cgaggaggag acggctgtgg acaaagttgc ggaggtctga cgtgtacctg ctgccgttct
    10861 tcagctaccg gcaggtcgac gacaccgtcg tcctcacgaa tcacatcacc aagaagcagg
    10921 ccgtcgacac gtgggcgacc gtggaggcgc tggaggcgat ctacaactcg ccgaccgatc
    10981 ccgtccgact ccccgcgatc gccgaggaga tggaactggt cttcgcggac cgcgacgagg
    11041 ccaacaggtg gctcgacacc ggaccgtccc ggcagacggg ccggctgccc aagatcgagc
    11101 agatcgaact gaccaaccgc tgcccgtaca cctgcaagat gtgcccgcgc accttcgaga
    11161 tggaccgcgg cctcggcgac atgtcgctgg agctgttcga ctcgatcatg cgccaggtca
    11221 gcggcgacac gaagttctgc gcactgcacc acttcgggga gtccttgctg cacaagggca
    11281 tcggcgaggc catcgccatc gcgctcggcc acggcgtgcg caccggcctg tcgtgcaatc
    11341 cgccgagtct gctgcccaag cgggccgagg cggtcctcac cgcgggcatc gcgaacatgg
    11401 tgctgtccct ggactccctg gacccggagg tctacaagtc catccgcggc cgggcggccc
    11461 ggttcgacat cgccgaccgc aatctgcgcg agctggtgcg gttgcgcaac gagggcggac
    11521 acgacaccaa tctcaccctc cagatgatca atatgcacgc caacaccgac gaggccgagc
    11581 agttcctcgc ctactgcgag gagctgggcg tcgaccgcgg tgtggtgatc cggctcgagc
    11641 gctgggactt cgacgacgag ctcgtggccg agctgggcga gcacacgtcg gccggttaca
    11701 ccgaaccgtg cacccggcca tggaactccg tggccatcct gtgggacggg cgggtcgtcc
    11761 cgtgctgcca cgactacaac ggcgagaagg tactcggcga tctccggcac gagacgcttg
    11821 aggagatctg ggcgaagccg gagtcacgcg agttccgctc ccgcaacgcc gagatggcca
    11881 tctgcggcaa gtgcgcgttc ggccagtcgt tccgggaggc caggcggcag aaggagggct
    11941 ttcaccggtt ccaccgggag gtgaccgagc cgagtggcgc gcggtgggag tggttcaatc
    12001 cgagcctgct cgacgcgggc cggaccaggg cttggtacga cggcttcgac gtgctgcccg
    12061 cggtgcccca cgagacggga gcgtgaacgt ggacgagacg cgatcgacga cgcgcgacgc
    12121 ggcggtgagg ttcgagtcgg ccggtccggc cgctcgggcc gtggtgctcc ggggatgggc
    12181 gtacgccgac gaggggctgg acgtcgccgg ccccctgctg ggcgcggctc ggaggtccgg
    12241 tgaccagacc gccgctcgcg acgcgtggac gtccgcggag aggccggacc cggcgcgcgc
    12301 cctgggaccg gtccgttcgg tggtcgtact gaccacggcc ggcgaggcca ccgtgtccat
    12361 cgcccacggc ggccaggcat ggctgcccgc cagggacgag gagccgccga cgtggaccgt
    12421 tcggctggat gccggtgcgc aggtcgtgct cgatgggcgc gccgcctacc gggtcgacgc
    12481 gggtgaggcc acttcgctgc tctggacagc cgcgtgacgc gaggaggcgg tacatgatca
    12541 cactgggtat cacgggcagc ttcgccgacc tggccggaac gttcatgccc gacgttccgg
    12601 agtggctgtt ccacgattcc gccgcggccc tggtcgtgga cgggaccgtg gtcgccgcgg
    12661 tcgaggagga acgtctcaac cggctcaaac actccaacct gttcccggcc tcggcggcga
    12721 aggcctgcct ggagctggcc ggcgtgcacg cggaggacat cgacgacgtg gcgttcttct
    12781 tcggggagga ctacgccgac ctggaggtcg gccacgagta tctgaagttc cccgacgtgc
    12841 ccgtcctgtc cgcgcgggaa ctgctgacga cgcgtctcac cgaggcgctg ggacgggagt
    12901 tccggcacgg tgacgtccac ttcaccaagc accatcgcgc ccacgcgttc ggttccttcg
    12961 ccgactcggg attcgacagc gcgctggcgg tggtcatcga cggcaacggc gaggccgagg
    13021 gtgtttcggt gttcgactgc gccaacggcg gtctgaagct gctgcacagc taccccgatc
    13081 agcactcgct cggacatctg tacctggcgc tgttgccctt cctcggcttc cgccgcttcg
    13141 acgagtacaa ggtcatggga ctcgcgccct acggtgcccc gtcggtgtac cgcgactgct
    13201 tccgcccgca ctacgcactg ctggacgacg gcgggtacac catgaacagc ggcgccgtgg
    13261 tggagcacct gctgcgcgcc gggttcgagc cgcgcaggcg cggcgagccg atccggcagc
    13321 aggactccga tctggcggcg gccctccagg cgacgctgga ggaggtggag cgccatctgc
    13381 tgagccactg ggtgcgggag acgggggctg cgcggctgtg tctgtccggt ggcgtggccc
    13441 acaactcgac ggccaacggc cgcgtcctgc agtggggtct gttcgacgag gtcttcgtcc
    13501 acccggcgtc gcacgacgcg ggcgcctcgg cgggcgcggc gcagcaccgg caggcggagg
    13561 tcaccggcgg ccgccggggc aaggggctcg tcaacgcctt cctcgggccc gacctgggcg
    13621 gccgggacgt ggtgcgggcc gagcttgccg ggtggagcgc cctggtggac gtggaggaga
    13681 tcgcgccggg cgaggagacg cggtacgcgg cgtcggcggt cgcggccggc caggtggtcg
    13741 gctgggcgca cgggcgttcc gagttcgggc cgcgggccct cggccaccgc agcatcctgg
    13801 ccgacccccg tgacgccggc agccgcgacc gggtcaacgc gatgatcaag aagcgggagg
    13861 ggttcaggcc tttcgccccc gcggtcctcg ccgagtccgc aggcgaggtg ttcgacctca
    13921 ccagcacgaa ggcgcgcctg gacttcatgg gctgtgtcgt ggacgtccgc cccgagtggc
    13981 gggagaagct gcccgccgtc acacacgtgg acggcagcgc acgcgtgcag accgtgcacc
    14041 gggacaccaa tccggtgatg tgggagctga tcgacggttt ccgtgcggcc accgacgtgc
    14101 ccgtggtgct gaacacgtcg ttcaacaact tcgccgagcc gattgtgcag tcggtgggcg
    14161 atgtcctgcg gtgtctggtg accacgacgc tcgacctggc cgtcgtgccc ggccacgcgg
    14221 tccggcgcaa gcccgggttc cgcgccgtgc tccacaccgc ggacgccgtg ctccacccgg
    14281 cggccctgct gcgcgaagtg gcgacggccg acggctcggt cgaacgcgtc gtgtcgttcc
    14341 gtacccaggg ggcgaaacgc gtcgccctgt cggagccggt gttcggcctc ctccgggcgg
    14401 ccgcatcgga accgacgtcg gcggcggccc gcgggctgcc tgccgacgag gaaacgctgg
    14461 acgcgctgct ccttctgtgg gagcaccggg tcgtggactt ccgggtccgc tgacgcctcg
    14521 acgatgaacc atccggggga tccgggcggg accactcccg atccggaccc cggaccccgg
    14581 acccccggac ccccggtcct ggcctcagga aggagacacc gtgaccgacc tgcgtttcga
    14641 cagcgtccgc ctcgacgtgc gggacatgga cgccgccgag gcgttctacc gcgacgccct
    14701 cggcttcgag cgggttttcc gctacgacct gccggacggt gtcatccaga tgatggcgcc
    14761 tggcggtcgg ccgcccggcg tcgaactcac catgctgcgc gatctcaccc cggccgccag
    14821 cccgaccgag cacgtcgcgt tcctggccga cgacgtgccc tcatgggtgg aacgcgtccg
    14881 ccgtctcggc tacaaggtgg agcgggagcc gttctccgtc gagggagaga cgatggcgtt
    14941 cgtcctcgat cccgacggcc accggatcga gctgaagcac tacagctgag cgtcccagac
    15001 gacgacgggc ttggcggtac gtcccgccgc catgtcccgg aaggtggccg tgccgaagtc
    15061 ctcggggccg accggggtgg ccagcgggct cggatcgagc acccccgcgg cgagcagccg
    15121 cagcacggcg tggaagtcgg cccggagggc cccgagcgac cagccgagcc gcagttcctt
    15181 gccgaacgcc aggccggcct ccaccggcag cgtgccgctg tgctgcgccg ccaccaggac
    15241 gtgcccgcca cgggcgaccg cgtccagcgc gtcgtggaag cccgtcaccg tgcccgacgc
    15301 ctccaccacg acgggaagtg caccgtccgg gcggccgacc ggcaggccga ggtccgccgc
    15361 cagcgctgcg cggcccggtg acgggtcgac caccgccacg tccaggcccc gcgcccgcag
    15421 cagcagcgcc acgccgagtc cgatggtgcc tgcgccgagc accagtgcgg gcccgtcgca
    15481 ggtgaccttg gccgccgcgt ggtgcgcaca ggccagcggc tccaccaggg ccgcggacac
    15541 cacgtcgata ccgtgcggca gccgcagcag cgccgaaccc ggcacggcca cgtaccgtgc
    15601 cagacccccc gagccgtagg tgtgtcccag cagcagcagc cgctcgcagt agctggtccg
    15661 gccggccgcg cacggggcgc aggcaccgca gtggaacgcc gggtcgacca ccacgggcgt
    15721 ccccacgggc cacccgtcgt cgctgtgcac gacggtggcc gcgatctcgt ggccgggcga
    15781 ggtgtccggc agcgtgccgg gccgttccac ccgcccccgg aagtcgatga ggtcggtgcc
    15841 gcagacaccc gcggcggcca cccggagcac cgtccgctcc gcgggcacgg accgcttcct
    15901 tccgacgacc tcgcccgcgg aggtcagggt gtacgcggtc ccctcgaagc cgtcagacac
    15961 cggccacccc cgccttccgc agggcctggc gggcgtccgt gccgtcggtg aaatggacac
    16021 cgatgccgcc gagcgccgcc atcgcttcgg tgttgactcg tttgtcgtcc accagcagca
    16081 tctcccgcag tggcgtgtcc gtggcgtccg ccaccagttc gaagaaccgg ggcgacggct
    16141 tgcgcacgcc gagccggcac gaggcgaaga cgtccacgtc cagtccgtgc aggtggtccc
    16201 gtaccacctc gtcgatccag tcggcgtagt tcgacccgat cacgaccgtg ttggcgacgg
    16261 tgcagtcgga caccaggtcg cgcatgccgt cgatccacgc gtagccctcg cggcgcaccc
    16321 ggtggaactc ctcgacgtcc cagttcaggc cgctgtcgac gagactgcgc cagtagtcgt
    16381 cctcggtgat ctcgccccgt tccagtcggt ggtacacgcc gtcggggcgc accgcctcga
    16441 actcgacgaa cgtgagcccg cacgcggcct cgtgagcgcg caggaacgga tcggtcagca
    16501 aagtgtccat caagtcgaag acgatgagca cggctctcct cacgaggggg gttgcagaat
    16561 gaccttgatc gcgcggtggg tccggcgggc acgtgcgacg gcgagcgcgc gcgccacatc
    16621 gtccgtggcg aacgtgtggg tgacgaggag gcggcccagg tccggcgccg cgccgagcag
    16681 gcgcaccgcc tcgtcgaggg agtccgccga ctcgggcggg cgggggctgg gttcggcggc
    16741 gtgttcgaga tggccgagca gggtcagccc cttcagccac agcgggctca ggtcggtgca
    16801 gtcgtcgggg ttgcccagcg tcagcaccct gccgcccgcg cggaccgcgc gcatggcggc
    16861 gatcagcgac gatgacgtgc ctcccgcgtc caccgcgagc cccggcccgt cgatgaggac
    16921 ttcggcgccc cggggccggg cgcccgggag gtcggccggc gtccgcaccg gctccgcgcc
    16981 cagcgcacgg gcggcgtccg cctggaagtc gtgccgtacc acggcgaagc accggctgcc
    17041 gggcagaacg gacgccaccg ccaccacggt gagcagcccc agtgtgccgc cgccgacgat
    17101 cacgacgtcg tccccggcgt ggtcgcgcac cgagcgcaca ccggagatcg ccaccgacag
    17161 cggctcggcc agcacggccg tgcggtcggg caggtcaggg ggcagcgtcc gcaccatgtc
    17221 ccggtgggcc cacacccagt cggcccaccc gccgccgaga tccgtgctga acccgaggga
    17281 cttgctccac cgcacggtgg gctgccagaa ggagtcacac tgcccgaacc ggccgttccg
    17341 gcacgatgcg cacagcggct cgtcgcgggc ggcgcaggtg acgagcggat gcacgacgac
    17401 ccgctcgccg ctgccgggac cgtcggcgag cacgccgacc acctcgtgtc ccggcacgac
    17461 tccggccggg tccgcggcgc cgtgcaccgg ggcctgagcc aggccacgca ggtcgctgcc
    17521 gcagatcccc gccgtggtca cccggacgag ccgccactgc ggtcccggcc gcggtggcac
    17581 ggggccgtgg acgagccgcg gccaccaggt gccgttcgcg ccgggcaccc gcaccacacg
    17641 cctgccggtc acgggaccgg ctgggcggtg gcgtcggcga agccgcggta cagccggtgc
    17701 gcggccgagc gcacctcctc ggccgagagg ccgcgggccc ggggcaggac cccgccggcg
    17761 cggctctgat ccgcgcacgt ccagtactgg tagcggctgc tcatcggatt gggcaccagg
    17821 cggacggcga gtccctcctc gccgcgcagc tcgccgcacc agcccagcag cgtggcgaaa
    17881 ctcaccggaa cacccgaccc gaggttgtac acgccgggtg gcggcggttg ccggatcacg
    17941 tccagcagcg tgtcggccac cgtctcgacc ggtacgtagt cccggcacgc ctccagcgtg
    18001 tccgcgaaca gcttgagcgg aacacccgtg gcggtctgcc gcagcagctg ggaaatgatc
    18061 gacgccatac tgcccttgtg ctcctcgccg gtgccgaaaa cgttggtgta gcggtagccg
    18121 gaccacggcg cgtcgtcgcc gaaccgcgcc gccatctcct ggtccagggt cagtttcgac
    18181 caggcgtagt cgttgagcgg gccggtgcag cggtcccggt cggccacgtc ctcctcggcg
    18241 accgcgaacc ggccgcggat cgtgccgtag acgctgtgcg aggaggcgta ggcgaagcgg
    18301 gtcccggaga cggcgcacgc ctcggccagg gccagcggct cgtcgacgtt caccgcccgc
    18361 agcaggtcac ggtcggtctc cagggtcgag ctgatcccgc cctggtgcag caccgcccgg
    18421 taccgcccgg cctgcacatc ggccagcagt ccggcgtcgc ccgcggtggc ccggacgaca
    18481 ccgccgacgg ccgatctccg ctccccgtcc ggcgcggggt ccagcgcggt cacggtgaac
    18541 cccgaacggc ggcacgccct cgccaggtga cttccgatga acccggccgc tcctgtgacg
    18601 agcacctccc cggtcatccg gtggcctccg gcgaggcggt gcgcagcagt gcctcgcgca
    18661 ccttcgcggt cttcgccgct gcctcctgtg cggtgtcgcg cacggtgacc tcacccaggg
    18721 tgcccagata gccgtccacc acgcccacgc tgagcgcgac cgaccgggac agcagggcgt
    18781 cggtgcgcgg caggtcgccg ggggcggcgt tccgtatccg tcgctcgccg ttcgcgtcgg
    18841 tccgggtgaa ctcgacgtgc agctggcccg cgcgggcgta gttgtgcttc gtcgaggtgt
    18901 ccagggtgga cccgcccagt tcgcgcgcga acgccgtcgc ccgcgccggt tcctcgaaga
    18961 tcagtacatg tgccgtgccg caccagccct cgtcgtggat gacgcggtgg ccgacacccg
    19021 gcacaccgtc aagaccttcg cgcaccacag ccgccagttc gcggcagtgc tccagcgcgc
    19081 ggtcgagctt gcgcacctgt gccaggccca gggccgcggc caactcgtgc atccgcaggt
    19141 tgagccccat ccgcgggccg tcctcgacca gccccgcccg gtccggcgcg aacccgtggt
    19201 cgtggaaggc gaacgcctgc cggtacacct cgggcgactc ggtgaccagc agtccgccgt
    19261 cgcccgtggt catcgtcttg ccggtgttga acgagaaggc gccggccgcg ccgatggtgc
    19321 ccagccgccg cccgcggtac gaaccaccgc acgcctgcgc gcagtcctcc agcaggggta
    19381 ttccgtctgc gaccgcgagc agccggtcca ggtcggcggg ggcgcccatc atgtgcaccg
    19441 gcatgatcgc cttggtgcgc gggccgagct tcgccgcgac gtcgtccgga gccagcgtca
    19501 ggctttcgtc gatctcggcc agcaccggcc gggcgccggt gaagagcacc gccgcgatgg
    19561 aggcgatgaa cgtgtagccg ggcacgatca cctcgtctcc cgggccgacg ccgagaccgg
    19621 tcagcccggc gacgagcgcc gaggtgcagc tgttaacggc cagggcgtgc gggctgccga
    19681 gcagtgcggc catctcccgc tcgaaccgca tcgtcttgga cacggccgac tcgtcgccga
    19741 agcggtagcg gctgagatgg ccttctcgta acgcctcgac gacctcgcgc tcctcggcgt
    19801 cgtcgatcag gtaccagcct ggaccgggca cctcggccct ccttccgctc gacgtgacgg
    19861 ctgatggaat acggtcgcgc aaccgtgtcg cggcgtggcc ggccggctca cacccggctc
    19921 ccgctgtcgt ggatgcggga gatcatgccg gtggtggaac ggccctcgac gtagggcacg
    19981 atcaccgtgc ggccgcccca ctcggcgacc agcgcggcct cggccacgtc ctccacgcgg
    20041 tagtccccgc ccttgacgta gatgtccggc ctgatggcct tgagaacctc cgccggcgtg
    20101 tcctcgccga acagcaccac cgcgtccacc gagctgagcg aggccagcac cgcggcgcgg
    20161 tcccgctgcg gcaccaccgg ccgggtctcg cccttcagcc tgcgcaccga gtcgtcgtcg
    20221 ttcaggcaca ccaccaggca tccgccgagc cggcgggcct ggtccagcag cgcgatgtgg
    20281 ccggggtgga tcaggtcgaa gcagccgcct gcagccacca cctcctcgcc ccgcccccgc
    20341 acccgcgcca gcagggccgc caggtcgttc cccgtcgtgc cgtgctccgt ccctccctgc
    20401 cgcgccggct ctgccgcggc gtcggccacc agcgcggacg ctccgcccgc ggccacgaac
    20461 tcggtcgcgg tccccacggc cgcggtcacc gcctcggcga gcagcgcccg gtcggcgagg
    20521 agcgaggcca ccgtgacggc gaaccggtcg cctgcgccgc aggtgtcggc cgcggcgacc
    20581 gggacgccgg gcaccaccag cggggcaccg tcgcgtgact ccagcagcac ggccccgttg
    20641 ccgccgcggg tgatcaccac gccgcccgtc tgccaccggt cgagcagcgt gccggcccgg
    20701 tcgatgtcgc ccaccaggcc cgtgccggtc ccgcccgcga agtgggcggc ctcccgggag
    20761 ttcgggatga ccagccggac accggacacc ggctcggcgc cgcgcgggtg cggatcccac
    20821 accaccggta tccggggggc ggcagcggtc agcgcctcac gcacggactc gtcgaacgtg
    20881 acaccgttcc cgtagtcgga cacgagcacc gcggcggcgc cgagcagcag gtcccgctcg
    20941 tccccggtca gccggcggcg tgaccggctc ctgcggtcgg aggcgcggct gagcatcagc
    21001 agcgagcggt cctccgtccg cacccgggac ttgaccgggg tggtgccgtc ggcgccgagg
    21061 tcgatcacgt gcacatcgtg cgagcgcagc aagtcggcca gctcgccgcc ctcctgatcc
    21121 accgacaggg ccgtgatcag cacgaccggc cggtcctgac gggcggcgag cagcgccgcg
    21181 aggccggcgc caccggggcg cgtccgcgcc tgtgcgttgt ccaccgtcgg caccggcgcc
    21241 tcgggcgaca gccgccgcac cacgcccacg atgtcgtggt cgagcagcgc gtcgcccacc
    21301 accaccaggg gcgccggagc gttcccgtgc ttcccgggcg cgcggctgga cgcgccgagc
    21361 gccacgtcga cctccgcgca cagcacgtgc acggcgacca ggtggcattc ctggatggtc
    21421 gccgtgccct ccgcctgcac cgccagcgtc tcgtcgcaca gctccgccag cgggttgggt
    21481 tccggcccgc tcaggcccca tacggtcagc ccggcctcac gggcggcccg tgccgcgcac
    21541 agcaggttct cgctgcgccc ggaggtggac agcagcatta gcacgtcgcc gggcctgccg
    21601 tgcgcccgga cctggcgggc gaacacctcg tcgaatccgt agtcgttgcc gatggcggtg
    21661 acgctcgacg tctcggcgtg cagcgcgatg gccgacagcg gctcgcgttc gtcgcgcagc
    21721 ttgcccacca gctccgatgt caggtgctgt gcctccgccg ccgatccgcc gttgcccgcg
    21781 gccagcagcc gcccgccacc gcccagcacg tccgccagcg accttcccca gctctcaagt
    21841 aaggccaggt cgaggccgac cagcgagcgc cggagccggg ccacgtgctg cgggccggtt
    21901 tccatgtggc tcatgtgccc tctcccatcg aggtgcgcga ggactcgacg ccccgctcgc
    21961 ggatttcggt gatagtcagg acgcggcccg gtgtgcccgt cgaggtggcg tggcgcactt
    22021 caccgcagaa gacgcggcag ccgcccgcgg cgcaggatgc ggtgacggcc atctccagca
    22081 cgcccgccac cccgccgagg accggtgcgc ccagtacccc cggcgaccac ggcaccgtgc
    22141 cgaaccggtc cacgtccgcg gcgaacaccc gcgcggtggc caggtcgtcg gcggccagca
    22201 cgtgcagcgc ggcgacgccg ctgcccgcca ccgcgcgctc cgtacgggag cccgcggtga
    22261 gcgcgaacgc caccacaccc gcgtcgtagc cgaccggcat gacggagccg acgagacatc
    22321 cgcgcggctc gtcgccgtcc cggctggtga ccaccacaca gctggtgagc agcgtgtcga
    22381 ggagggagcc accgatcatc cccgctcccc cagcacatcc gggaccacat cggccacccg
    22441 ggtgcggaac agtgccttgc cgccgggcca cacctccggg ttgccggggt cgacgccggc
    22501 ctccgcggcc cgcgaggcca ggaacgcggc gctgggcacc agcagttcca ccggcgccca
    22561 gacgtcgtcg cacccggcct gccacaccgt ggcctcgacc cccggaggga gcgagtcgac
    22621 cgtgccctcc accagtggcg cccagcgccg ctctgccagc accagcacac tcgtcgaccc
    22681 ggcgttgcga tagaggccga cgtgtctgcc gtgaccgagg ttgcgcagat cgctgatggt
    22741 gaccaccccg agtcccgcct ccatggcccg ggtctccagg tccaccgcca cattgcgcag
    22801 gccgggtgtg tggaggcaga gcaggcgcgg ccgggtgagg tcggcgtccg cccgcaggag
    22861 tccgcccacg acccagcgcg ccaccacctc gtccgggtcc ggcgcgccct cgtcggctcc
    22921 cagcagggtc agcgcgccga ggctcaggct gagcaccgag ttcgtcgcga tccacccgtc
    22981 gcgccccggc cggggcgcgg acacgatcgc caaccggtct ccgagacggt cccgcagctc
    23041 ctcggcgggg cgattcgaca gcaccacggc gcaggcccgg ccggccgcgg cgtggtcggc
    23101 cgccagccgg gcgtcgggat gactcatgct gtcggagatc accacaacgg tgccgaactc
    23161 caccggcgac agggcgaact ccaccggcgt gagcacggct gccggctgcc ggtatcggcg
    23221 ttcgtagacc gcggcggcca ggtgcgccac cgcgagcgag ccgcccgagg cgacgaacgc
    23281 ggccgggccg cccagcccgg tcaccgcgcc gggtcccgcc tcgccccgcc agcgctgcca
    23341 ggcgcgccag gtggcgccga gtgtggcgat ttcctcttcg taggtacggt ccactggtcc
    23401 tcccggacag ctccccgagt acggcgggat cggcgcgtca gggcgtgccc gcgcggcggt
    23461 cgacgtcggt ggccctgctg gtgggaacgg actgagcggt catgtctgct gctcctcgtg
    23521 gtgagtgccg gccggctttt cctgcctgtg gtcgatgtcc gtgctcgggt cgacctggag
    23581 accgtgggtg atctgcaatc tcgccaggag ttgcagcccg ccgtcctgga cgccgcggaa
    23641 ctcggtattc agccaggtgc ggtagtcgcg ggtgtagcgc tcctcgaaga tccgccggga
    23701 cagccggaat cccagcggtc gtcccaccgc tttggcggcg tagaacgtgt cgaagcacat
    23761 cgcgcagtcg ccgcaccacg gcgcggcggc ggtgcgacgg cagccctcca gccggtgctc
    23821 ggcgcccggt ggcagcgagg ccagcatccg ttcgcgggtg agctcgccgc acaccgtgcg
    23881 cagccgcagc gccgggtgga actcgttcca ccgcgcgagg aactccaggt ccgcgtcgat
    23941 gtccgccggg ccggacggtc cagcgggcgc ggccagggcg gcgcgccggg cgataccggc
    24001 gtaggaacac gccgcgccgc ggtgcgccga caatacggcg agggtgaaca gcagtggtgc
    24061 gccggcgcgg tgcggctcga cctcggccgc gaagctgcgg tagctcagcg gcgtgggcga
    24121 caggtggctc accagcaggt cggtgtaggc cgaggcgaga ccgcccgagc accactgcgc
    24181 gacctccccg gtgggttccg ggaacgccag gcccgcgggc gggccggcct cgacgcggac
    24241 cgcgccgccc cgctgccact ccgcgtacca ggcccagaac ggcgttcccg cgtccgcggg
    24301 caccaccagc cgctcgcacc ccggcgacac cagttcgcgg cgcaggcgga agtaggtcac
    24361 cgcggcggtg tcggcgatgc ccgcgccggt tgccgtcccg gtcatcactg gttggtgagg
    24421 taggccacgg acacggcgag ctgatcggcg agcagtccgg gttggcagtg cggctccagc
    24481 gtgaacggtc cgtcgtagcc cgctgcctcc agc
//
