LOCUS       NZ_LZNS01000001        25666 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1149709
            Orig. end                         :: 1175375
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25666
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="deazapurine"
                     /region_number="10"
                     /rules="(GTP_cyclohydroI and PTPS and QueE and QueC and not
                     (dpdA1 or bTGT))"
                     /tool="antismash"
     cand_cluster    1..25666
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /kind="single"
                     /product="deazapurine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25666
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15666]"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15666
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
     misc_feature    223..237
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.98"
                     /tool="antismash"
     gene            272..3433
                     /locus_tag="STBA_RS04825"
                     /old_locus_tag="STBA_09770"
     CDS             272..3433
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432430.1"
                     /locus_tag="STBA_RS04825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09770"
                     /product="glycosyl hydrolase 115 family protein"
                     /protein_id="WP_253194530.1"
                     /transl_table=11
                     /translation="MTSRRSFLSLLPLTVAATAVPTAAHATPAVTAAPATGGRGARGTF
                     VSTSWRPGSLALVANGKAAPVLVSSQDHPGVLRVADDLAADIARVTGVAPDLMRDEVTG
                     RHDEVVIVGTIGRSPLVDGLIEAGKLDVDGIAGRWETTRQQVVAHPLPGVRRAFVIAGS
                     DQRGTIFGAYEASRQMGVSPWYWWDDVPAPTHTELYALPGRHTQGTPAVKYRGFFINDE
                     NPALGTWAPAFFGPGHAPGFPNGFNSAFFAKVFEVMLRLKANYLWPAVWGRAFAEDDPE
                     NHATATAYGIVMGTSHEAPMMRGIEEWNRHAVPAVRDEDGNVVTPGTDPYGGTGEWSFR
                     RNGEAIKQYWADGVRRMVEQDFEGVVTLGMRGNGDVSLPDGDGIDLMQSILESQRAILA
                     EVTGTDDLTAIPQVQTLYKEVQRYWDQGLRPPDDVTVIFCDDNWGNMRKVPERRLAERA
                     GGYGLYYHFDYVGGGRNYKWVDTVNLASTWEQLHLSYRSGIDRLWVVNVGDLKAEEMPL
                     QFFLDYAWDPERWTIDRLAEWERQYAEQSFGPRHAEAIAEVLHTYGVLQARRKPELLNR
                     RITLDPAKDPATDSSAVVYDDRATPFSIEHYRELDRVTEAWERLDAEAQRIGDELDAAH
                     QDAYYQLVQYQVEATANLYALRHAEFTSLHYAAQGRAAANQLADATDARFADDQAMSDY
                     YNNTLADGKWAGFQTQPKIGYGDVERYGPDAPWQQPQTPDHVALPDEVFPPVRRVELPE
                     GPEMGVAIDGSALWWPAADTPARLPSFSPFQSQPAQYIEVFNRGAAPFAYRIEPAEPWV
                     TVTESSGTVETQVRAEVAVDFAAAPHGTTTVPITVTGPDGVRVEVLAVVENPDVPRRRL
                     AGFIEANGYVSIEAAHHSRAVNTSGVRWQRIPDIGRTGDGMTPFPVTASRRTPGGRGPR
                     LEYELTLFTTGEVRVYAYLSPRNNVLPTDGLSYAVSFDEAEPQTVNVTEVTGADDTAMN
                     KQWERNTSDNVNLTVTTHTVAEPGRHVLKFWMVDPTVVLQKIVVDTGGLNPSYLGPPES
                     TRARD"
     gene            complement(3484..3678)
                     /locus_tag="STBA_RS04830"
                     /old_locus_tag="STBA_09780"
     CDS             complement(3484..3678)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177552.1"
                     /locus_tag="STBA_RS04830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09780"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_077058038.1"
                     /transl_table=11
                     /translation="MTSADPMPHGVWRGSSYSGNNGGECVEVADGFPGVVPVRDSKNPG
                     PVVAVPAGAWSVFVERVKR"
     misc_feature    3752..3766
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.04"
                     /tool="antismash"
     gene            3927..4109
                     /locus_tag="STBA_RS04835"
                     /old_locus_tag="STBA_09790"
     CDS             3927..4109
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="STBA_RS04835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="STBA_09790"
                     /product="hypothetical protein"
                     /protein_id="WP_077058039.1"
                     /transl_table=11
                     /translation="MDRPLPRPGGTRAPKAVDAFAAAYVRMYWTFAFRRPEERWLKAMA
                     EAAESWANHRGLVVV"
     gene            complement(4168..5034)
                     /locus_tag="STBA_RS04840"
                     /old_locus_tag="STBA_09800"
     CDS             complement(4168..5034)
                     /NRPS_PKS="Domain: Abhydrolase_1 (46-170). E-value:
                     1.3e-08. Score: 26.7. Matches aSDomain:
                     nrpspksdomains_STBA_RS04840_Abhydrolase_1.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677092.1"
                     /locus_tag="STBA_RS04840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09800"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_079251720.1"
                     /transl_table=11
                     /translation="MAPSPRTQPRTRLLHDASRHEFRDPARPRPVRLYLWEPQRPPAAP
                     APLVVVSHGTGGSGSAMGWLARPLAEAGLRVVALDHHGNNFVDGYEPEGFAFVWERARD
                     VSFVLDVLAGERPLGPVGAAGFSLGGYTVAALAGARVAPQVMAAVLAGQASLPALPEFP
                     DLLGALGEKVPADELRAAIGGAGADVSDSRIRAVFQVAPAVGSLLTPQSLKAVRVPVEI
                     RWGGADTITPFDDDTRPYLAHIPTAVGRSVGSDVRHEDFFEAEPAGEPVRARVAGEAAA
                     FFRRHLS"
     aSDomain        complement(4525..4896)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STBA_RS04840_Abhydrolase_1.1"
                     /evalue="1.30E-08"
                     /label="STBA_RS04840_Abhydrolase_1.1"
                     /locus_tag="STBA_RS04840"
                     /protein_end="170"
                     /protein_start="46"
                     /score="26.7"
                     /tool="antismash"
                     /translation="PLVVVSHGTGGSGSAMGWLARPLAEAGLRVVALDHHGNNFVDGYE
                     PEGFAFVWERARDVSFVLDVLAGERPLGPVGAAGFSLGGYTVAALAGARVAPQVMAAVL
                     AGQASLPALPEFPDLLGALG"
     misc_feature    complement(5069..5085)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            5096..5980
                     /gene="fdhD"
                     /locus_tag="STBA_RS04845"
                     /old_locus_tag="STBA_09810"
     CDS             5096..5980
                     /GO_function="GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fdhD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191523.1"
                     /locus_tag="STBA_RS04845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09810"
                     /product="formate dehydrogenase accessory sulfurtransferase
                     FdhD"
                     /protein_id="WP_077058040.1"
                     /transl_table=11
                     /translation="MGRMTERRRVVRIRDGVLSERADTLVGEEPLEIRVAGRQVAVTMR
                     TPGDDFALAAGFLVSEGVFACAQELARIAYCAGATEDGTNTYNVVDVRPAEGIELSGLA
                     LDRLARNVYTTSSCGLCGKASLDAVRTTARWPLPLTGGPRLTPEVLSALPERLRAAQRV
                     FRSTGGLHAAGLFTADGGLIDVREDVGRHNAVDKVVGRALTRGALPLTDTVLMVSGRAS
                     FELVQKAVMAGIPVLAAVSAPSSLAVDLAAESGVTLVGFLRGTSMNVYAGAERLALSVS
                     SGPSGSSDQRLAR"
     gene            complement(5902..6909)
                     /locus_tag="STBA_RS04850"
                     /old_locus_tag="STBA_09820"
     CDS             complement(5902..6909)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951953.1"
                     /locus_tag="STBA_RS04850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09820"
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="WP_077058041.1"
                     /transl_table=11
                     /translation="MSVVRRLTRFLDPYIVLLLGTVGLAALLPASGPAAGAVDGAATGF
                     IGLLFFLYGARLSTREALDGLRRWRLHLAVLAATFAVFPLLGLAARGLVPWLITDELYD
                     GLLFLCLVPSTVQSSIAMTSLARGNVPAAIAAGSFSSVLGVLLTPLLAAVLIGSSGGFS
                     ADSLLAICGQLLLPFLLGQLLRRWIGGFVRRHRRVLSLVDRGSILVVVYAAFSQGMNAG
                     VWQEASWRRLLALFGVEVLLLAALLLLTAWVARRLRLPREDRIVVVLAGSQKSLAAGLP
                     MASVIFQGQAALAVLPLMMFHQMQLIVCAYLAKRWSDDPEGPEETDSASRSAPA"
     gene            7006..7848
                     /locus_tag="STBA_RS04855"
                     /old_locus_tag="STBA_09830"
     CDS             7006..7848
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004980961.1"
                     /locus_tag="STBA_RS04855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09830"
                     /product="aldo/keto reductase"
                     /protein_id="WP_077058042.1"
                     /transl_table=11
                     /translation="MSSVPHVTLNNGVKMPQLGFGVWQVPDADAEVAVGQALDAGYRSI
                     DTAAAYQNEEGTGRALAASGLPREELFVTTKLWNSAKETWTRDAVLREFDASLARLGLD
                     YLDLYLVHWPRPMRDDYLTILRTFDEIHRTGRARAIGVSNFKPPHLRRVVEETGVVPSV
                     NQIELHPYLQQAETATLDAELGTVTEAWSPLGSGKGLLDDPALTAIADKHGRTPAQVVL
                     RWHLTTGHVAIPKSVTPSRIRENLDVFGFDLDADDMAAVDALDAGVRTGPDPDTFDWN"
     gene            7937..9529
                     /locus_tag="STBA_RS04860"
                     /old_locus_tag="STBA_09840"
     CDS             7937..9529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925670.1"
                     /locus_tag="STBA_RS04860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09840"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_077058043.1"
                     /transl_table=11
                     /translation="MTNARTHRTLAALAALGGILAAVAGLAAGELAAAAVRPEAAPVAA
                     VGEAAIALAPVPVTTWAIDTFGTNDKPVLEAGIVVVLVLFAAGLGLLARWHRAAGPAGA
                     AAFGAVGALAAVTGPGARPSDAWPSVVAAVAAAGVLALLAGRLRAAPAPRNDGAAAAEP
                     AAPADRRRFLTAAAATAAASAGAGLLGRTLHSADSAAAAASRSALALPAADAAAPPVPP
                     GARLNVPGLAPFITPNDRFYRIDTALRVPRVDAERWRLRIHGAGVPRPVTWTLADLFAR
                     EIVERDITLACVSNPVGGTFVGNARWLGVRLDGVLRDAGVRPPSRGGPADQLVAHSVDG
                     MTLGSPLETVMDGRDALLAFGMNGEPLPFAHGFPVRMVVPGLYGYVSACKWLTELELTT
                     FDAFPAYWTDRGWAERGPVKTQSRIDTPRGSAPPRAGLVPVAGVAWAQHTGIDRVEVRV
                     DEGPWQEAELAEEDTADTWRQWRFDWRAEPGEYRLQVRATDRGGRTQPAEESGTAPDGA
                     TGRHTVTVRVVDA"
     gene            complement(9542..9847)
                     /locus_tag="STBA_RS04865"
                     /old_locus_tag="STBA_09850"
     CDS             complement(9542..9847)
                     /EC_number="4.2.1.96"
                     /GO_function="GO:0008124 -
                     4-alpha-hydroxytetrahydrobiopterin dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006729 - tetrahydrobiopterin biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571771.1"
                     /locus_tag="STBA_RS04865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09850"
                     /product="4a-hydroxytetrahydrobiopterin dehydratase"
                     /protein_id="WP_077058044.1"
                     /transl_table=11
                     /translation="MAPRPLTGQEIEQALAGLPGWTLEDDRLVRSYGLAGHLPAVALLV
                     HIATVQEELDHHADLALTYNRLGVAVHTHSVGGKVTELDVRLARRIEDLAPAHGAS"
     gene            10001..10366
                     /locus_tag="STBA_RS04870"
                     /old_locus_tag="STBA_09860"
     CDS             10001..10366
                     /EC_number="4.1.2.50"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070497 -
                     6-carboxy-5,6,7,8-tetrahydropterin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: PTPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016577818.1"
                     /locus_tag="STBA_RS04870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09860"
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="WP_077058045.1"
                     /sec_met_domain="PTPS (E-value: 1.3e-32, bitscore: 111.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFRITKEFHFSASHRLDGLPEGHPCGRLHGHNYVVELELAAAAD
                     GLDEVGFVRDYGELKDFSRWLDHEVDHRHLNDLLADRNPSAENLSRWLYERWLPRYPEL
                     SSVRVSETAKTWAEYRP"
     gene            10476..11123
                     /locus_tag="STBA_RS04875"
                     /old_locus_tag="STBA_09870"
     CDS             10476..11123
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016577817.1"
                     /locus_tag="STBA_RS04875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09870"
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="WP_253194532.1"
                     /sec_met_domain="QueE (E-value: 5.4e-69, bitscore: 230.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.7e-12, bitscore: 45.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3e-13, bitscore: 49.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRRCAFLRLGGCNLACRWCDTPYTWDWTGIGDSGVAYDPRTELR
                     AMAWEEVLRRLRAYAVPMIVISGGEPLSQQKRLVPLLRALAGSGHRIEIETNGTVTPRP
                     ELVELVRFNVSPKLAHSGDPESRRLKPEALAALAAAPGTAFKFVCRTPGDLDEVAAVVE
                     RFGTTPVWIMPEGRNREELDRNLGTLGDEVIARGWNLTTRLHIAVWGNRRGI"
     gene            11123..11701
                     /gene="folE"
                     /locus_tag="STBA_RS04880"
                     /old_locus_tag="STBA_09880"
     CDS             11123..11701
                     /EC_number="3.5.4.16"
                     /codon_start=1
                     /gene="folE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: GTP_cyclohydroI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356712.1"
                     /locus_tag="STBA_RS04880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09880"
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="WP_077058047.1"
                     /sec_met_domain="GTP_cyclohydroI (E-value: 1.8e-50,
                     bitscore: 169.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSAYENRPETHDPLEDVARRLLVEIGEDPDRDGLKETPARFAR
                     WWREFSGYDAGEADTRFPLRTSGQIVMVSDIHVWSLCEHHLLPFSCVLTIAYKPHGDVL
                     GLSKFARIAHRHAHRLQVQERLIQDVAEDVSAATGSPDVAVIGQGEHLCMSMRGIRTPA
                     LMTTSVFTGIFEEYGPARDELVATAFPRR"
     misc_feature    11312..11314
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11727..12896
                     /locus_tag="STBA_RS04885"
                     /old_locus_tag="STBA_09890"
     CDS             11727..12896
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036879.1"
                     /locus_tag="STBA_RS04885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09890"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_077058048.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.6e-07,
                     bitscore: 29.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIALVLLTYNPDEPAGVERAVASLADGLRELGHRAVIIAAGPAG
                     EDDDENLLRLPTLNLPRPVQFDEEQRLLTEHEPLRREILTLLDQHRIDVVCWSDAVVGL
                     GFLSPAPAEVRTALMVHFLRVDEPMRESLAHGPDAVLAVSPFMIEEAARAGLDSSGWHA
                     LPNALLGVGEPPPPEERERLRRTGPVRVVARADPSKGVAELLRAHPDGWGRPVQVVLAA
                     AGFELWPGMQDDVFEECRALAGNRPDIEILPPLAWDEVQPFLAGAAVTLVPSTSPETFG
                     NVPAESLSVGTPVVGYGFGHLPALAGPAGRLVGLDVVSGFGHLPALTGRALDMVDFAEG
                     PKRLWEATADLLADREAYHAAARQAPHQVAEHTPAAVAAAFLRATLGTA"
     gene            12893..14149
                     /locus_tag="STBA_RS04890"
                     /old_locus_tag="STBA_09900"
     CDS             12893..14149
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /locus_tag="STBA_RS04890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09900"
                     /product="glycosyltransferase"
                     /protein_id="WP_077058049.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.7e-21,
                     bitscore: 74.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGGPRICVVIPTYERAALLRGTLDALAGQRLPTAEFEVVVSDDG
                     SHDDTREVVAGFADRLSIRYRFQEDLGFRAAAARNAGARLASAPVLAFVDAGILPGPDF
                     LAAHLAAHLAVPEGAAQDPPRAVIGYTFGYRPGSPTPGLGDAVRVMTPEELVGHYGDAP
                     DFRDARHLAFARFGFDLGRSAVPWQWFWSMNCSVRADDFLALGGFDESFRSWGGEDLEL
                     GFRLFRHGVRPVVSRDAWAVDVPHPRAASADLASNHANFLAFLHKHPEPVVELLWAWFA
                     RERPGFEVRHDWNTEDEYLLLLDAAAAAGSVDVTRELAPLRDVAPGTRIAVLGCGASIP
                     PWLPRAELFDFDRHAVNAAARSGRSVRHAIGLRTTLPDDSFDIVLVTSRLKDLWSRWRP
                     QLLAEARRIGGDLRGPLSG"
     gene            complement(14161..14907)
                     /locus_tag="STBA_RS04895"
                     /old_locus_tag="STBA_09910"
     CDS             complement(14161..14907)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016908.4"
                     /locus_tag="STBA_RS04895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09910"
                     /product="FkbM family methyltransferase"
                     /protein_id="WP_077058050.1"
                     /transl_table=11
                     /translation="MTGIRNITLDTGLDFWAPHEAEAHWQYEEIFKLGCYSGIRLPPGA
                     YVIDVGANIGLFTYFLKRGCPTARVRAFEPMPEALASLRRNIEAHGLTGITIEECALGS
                     GTEDEVPFVYYPQAPGNSTRYPEEKELQIAVLAREAPEEYIRAHYRGYSVPVQVARLSS
                     YLVPGERVDLLKIDVEGAELDVLRGVDTEHWPLIGRLVLEVQDLDGRLDAIGDLLRGHG
                     FVVDARPSPLIPEDVRTFLVHAVRPG"
     gene            complement(14950..15666)
                     /gene="queC"
                     /locus_tag="STBA_RS04900"
                     /old_locus_tag="STBA_09920"
     CDS             complement(14950..15666)
                     /EC_number="6.3.4.20"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570258.1"
                     /locus_tag="STBA_RS04900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09920"
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="WP_077063111.1"
                     /sec_met_domain="QueC (E-value: 1.3e-56, bitscore: 190.1,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.1e-07, bitscore:
                     30.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQDTSSPDPFTAVVVLSGGMDSTALMAHYAALRFRLVAVTVDYG
                     QRHRREIDAARDIAAHYGAAHRLVDFSGFGSLLAGSALTDESVAVPEGHYAEEAMKATV
                     VPNRNAVLANIAVSVGVACRAGVVALGMHAGDRAVYPDCRPPFLTALQELVAVANEGFP
                     TPRVEAPFLTWTKAAIAAHGAGLGAPLGRSWSCYKGGDQHCGICGTCYERREAFEEAGL
                     PDPTTYLDGVTRFAVP"
     gene            complement(15732..18692)
                     /locus_tag="STBA_RS04905"
                     /old_locus_tag="STBA_09930"
     CDS             complement(15732..18692)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="STBA_RS04905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09930"
                     /product="AAA family ATPase"
                     /protein_id="WP_077058051.1"
                     /transl_table=11
                     /translation="MTGRARPRPPAFVGREAQLRALGRARRDCPEKGLVRCVVTGEPGA
                     GRTALLGAFARAARAEGSTTVGLVGRRRDRHVPGALVEELVLALADALPAGSEPQTRLR
                     SVQERLGAEDFCSAVPGPGRGPALWPTVLSAVTVLAARAPLVLTVDDVCRAGPGALAAL
                     QLVLETCAHLPVVVVVSVRPGEPAEAPPELAELLLDARQLALDGLSERETALLMRALLP
                     RVPTAGLVGACHRLTAGNPLLICELAGWVRDGLRAARGPVVPESAVLPEVAELVRGRVA
                     RIDADAGRVAEAIAVAAGRGGADTSLVAHLSGIGLSRTLNALDLLVRMRLVADEDSLRL
                     RHPLLAQSLLGAMTLMARNAAHLTIAAYLHERGAPAEWIADHLIASTVPPGGAWPVGAL
                     LRAARSAEDATALRYLELAVRTAAGEEHRVAMLELAAARVRADPAAGLGAAVDMLARAT
                     DHVTRARLLGHIGRALDGAGLPEAAQRVPDQVAALVDGTPLHGWPHLHRCLTHFYESPP
                     ADTAKIIEDLPGRPPSAGRDGVPRTHAAATAIGAFCRFLVDDDPRAAVRRARWALGRSL
                     DELGLHPLALPSALTVLGESGHHDEAAAHVRRLDGFAQGWPSASRAMLLLVEARIALAA
                     GEVPTARGRLAAALERTAGYGAAASDPVLVCTVGLLAGVLLSLDEGAEAEALLRRHGYL
                     GELPPGWHYQDLLLARARLRAAGSDLVGAGRDMAELLERGRDAGLRATGTVSWRMHGVA
                     LLDQVGRTEEARQLARQQVRFAGSTGSAGERGRALRVLGRVEGGTAGEHLLNEAVSLLE
                     NTQDTYDLAHALGDLGCLLIRLDRPDEALAVLTRAVRLADRCEARALSGQLGQQLLAAD
                     ERAPQHVSLRGILALTRRERQILVDAMRGLTNKRIATMRQITRRTVELHLSSAYRKLRI
                     DGRGDFPLVFCNPGLWTLLTDGALAARRHPAAPRPAVTGARGRASAGSPQSFGLGP"
     misc_feature    complement(18102..18104)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18105..18107)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18689..19543)
                     /locus_tag="STBA_RS04910"
                     /old_locus_tag="STBA_09940"
     CDS             complement(18689..19543)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356720.1"
                     /locus_tag="STBA_RS04910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09940"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_077058052.1"
                     /transl_table=11
                     /translation="MPHLDENAIRTHPLCGPLDRMPAEYRGPRRLGRDGWLNFVQRLGR
                     GEEIDLVRAATAGGRRILDVGGGTGELTRAVAAESGRCTTVEPHRDRVATLHLATEAEG
                     AGVIEAFPGRAESLPFPDASFDVVFSTWVLPFVDDLQRSVREMARVCDLSDPGARILLI
                     GGAPDNELINILNEVCAPIAGEPYDHHGFLLVTAAEILAEEGFRRFALQRTESALHFPE
                     ISLEERIDAACTVLVDFWYEGHPRAADMRSALRPAVRGHFERRPHAIGDQGTVLVARPG
                     APS"
     misc_feature    complement(19517..19528)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.02"
                     /tool="antismash"
     misc_feature    19612..19625
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.63"
                     /tool="antismash"
     misc_feature    complement(19801..19812)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.2"
                     /tool="antismash"
     gene            complement(19996..22098)
                     /locus_tag="STBA_RS04915"
                     /old_locus_tag="STBA_09950"
     CDS             complement(19996..22098)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848477.1"
                     /locus_tag="STBA_RS04915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09950"
                     /product="phage holin family protein"
                     /protein_id="WP_077058053.1"
                     /transl_table=11
                     /translation="MADRKKGRSVPVTTWRNAGAALLRVLAVWAVSTLTMVLLALVLPG
                     FHLQSADGDSFTRIGITAALGAGCFGLLNALVWPWLVRAMLLVPALALGLLVFLLNGSL
                     LWLALSAIPDGRGTAGPSTAVVVAAVMSVAASATSTFLAVRDPDAQARRLRRMAGRRAA
                     RSGTARHTDTPGIVFLQLDGIGHRRLCDALEGERPQMPALAALLGTTHRLTPWHTDWSS
                     QTGAAQLAILHGSNEDVPAFRWYEKDTGEVIVSNRPSSAAELQRRAVERTGSAGLLAQD
                     GASRGNLFTGGAGQAALVLSVAARRGRGQRSRAGYFAYFSDPAHAARTAASFLAELVRE
                     IAQALRARLTGSGPRVSRGGLYPFIRAFATVVQRDVVTAAVIGDVLNGRTSVYADLVAY
                     DEVAHHSGPDSRDTRPVLARLDRCVATILRAVEHAPRPYHLVLLSDHGQSHGETFEAAY
                     GHTLEELVRIGCGRPVPRPPRRQETGAEARGAARVALHRPERPARPRPAEDDRQERGRA
                     PVVLASGNLGLISLPDVPGRAGRRTIERRCPALLRTLAEHPGIGFLLVHDERHGPVVLG
                     AGGAEHRLTTGEIVGHDPLAPFGPRAAAAVRRTAGFAHAADIMVNSSVDQDTGDVHAFE
                     DQIGCHGGLGGEQSRAFLMSPLALSAPAPGLVGAEAVHRELLRWQREAMLRPTPAQPAH
                     APSRPR"
     gene            22172..22948
                     /locus_tag="STBA_RS04920"
                     /old_locus_tag="STBA_09960"
     CDS             22172..22948
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071349.1"
                     /locus_tag="STBA_RS04920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09960"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_077058054.1"
                     /transl_table=11
                     /translation="MPVDITWWGHATATVLDSGTSVLTDPLFTRRCAHLRRRRGTLPPV
                     AARRADVVLVSHLHADHLHLRSLARLAAGTPLLLPRGALRAVPGLRRLAARLEVCEVTP
                     GDRVPVGGLTVRAVPAAHDGRRLPFGPRRVSALGYVVEGEARTYYAGDTDLFEAMAREA
                     GPVDMVLLPVGGWGPRLGNGHLNAERAAEALTRLRPRGAVPVHYGTYWPFGMAGVRPHE
                     FHSPGDEFVRHAARLAPAVRVHRLRHGESVRLAVAG"
     gene            22945..23637
                     /locus_tag="STBA_RS04925"
                     /old_locus_tag="STBA_09970"
     CDS             22945..23637
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309438.1"
                     /locus_tag="STBA_RS04925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09970"
                     /product="VTT domain-containing protein"
                     /protein_id="WP_077058055.1"
                     /transl_table=11
                     /translation="MTTAGAECALAASRAVSPDTTQQAIGYPSLFLLVLLGALVPVVPT
                     GAVVSSAAAVAFHHSNAAAFSLGVFAVAAAAAFLGDAILYALGGRGVRSRNGSRWLDRI
                     REQVAPEPLARAQERLARRGATVLLVSRLVPAGRIPVMLACLLARMPLHRYLRGNLPAV
                     LGWAATYQLLGMLGGALFPHPWQGVVAAVTLTLLIAAAPVVLRRLRQALGRPAAGRPRP
                     ARGLRGRG"
     gene            complement(23525..23980)
                     /locus_tag="STBA_RS04930"
                     /old_locus_tag="STBA_09980"
     CDS             complement(23525..23980)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076576.1"
                     /locus_tag="STBA_RS04930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09980"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_077058056.1"
                     /transl_table=11
                     /translation="MNVGPQADGADDVFVRDCPTRTVLDHVTSRWGVLVLVALREEPLR
                     FYQLRDRIGGISEKMLSQNLRVLTEDGLITRRVEPVVPVRVSYALTDIGRELTAPLRTM
                     IDVIAARLPEIIRAREAHAPGAAGPPPAGRGPAADGAGPPAPPRSAA"
     gene            24044..24694
                     /locus_tag="STBA_RS04935"
                     /old_locus_tag="STBA_09990"
     CDS             24044..24694
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433044.1"
                     /locus_tag="STBA_RS04935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_09990"
                     /product="DsbA family oxidoreductase"
                     /protein_id="WP_077058057.1"
                     /transl_table=11
                     /translation="MSEITVEVWSDLVCPWCYIGKRRLERALADFDGRDEVRVVWRSYQ
                     LDPEAPATADLTLPAHLTERQGLPPEQVAEMLGRVTGIAEGDGLAYRLAEARPANTFDA
                     HRLVHHAAGLGLGAAVQERLLAAYAQEGIALAGHETLARLAAEAGCDEAAARRALANGD
                     HADAVREDIATARQLGITGVPAFVLDRAFLVSGAQPAEAFGRVLRELHTRGAA"
ORIGIN
        1 cgggcggccg gcacgcggtg catctggaac ggcccgcgga attcgccgcg ctgatccgtc
       61 gccgggccgc tgctgccgcc gctgctgctg ctgctgaaaa cttttcatag ggcggaagca
      121 caccaggccc gcccaggtca ccgaaccact gccgcccccg cgcggatcac gccggtgacg
      181 gagtattgac ccacgccagg cccgtcatta ctttcttccg gaaccatccc gaaaattatc
      241 ggccatccct tcctccgggc ggagaatgac cttgacgagc cgtcgttcct tcctcagtct
      301 gctccccctg accgtcgccg ccaccgcggt gcccaccgcc gcccatgcca cacccgccgt
      361 caccgccgca ccggccacag gtggccgggg ggcacgcggc accttcgtgt ccacgtcctg
      421 gcggcccggc agcctcgcgc tcgtcgcgaa cggcaaagcc gcgcccgtcc tggtgagttc
      481 gcaggaccac cccggcgtgc tccgcgtcgc cgacgacctc gcggccgaca ttgcacgcgt
      541 caccggcgtc gcgcccgacc tcatgcgcga cgaggtcacc ggccgccacg acgaggtcgt
      601 catcgtcggc accatcggcc ggagtcccct cgtcgacggc ctgatcgagg ccggcaagct
      661 cgacgtcgac ggcatagccg gccgctggga gaccaccagg cagcaggtcg tcgcccaccc
      721 gctgcccggc gtgcgccgcg cgttcgtcat cgcgggcagc gaccagcgcg gcaccatctt
      781 cggcgcgtac gaggcgtccc gtcagatggg tgtctccccc tggtactggt gggacgacgt
      841 gcccgccccc acccacacgg agctctacgc cctgccgggc cgccacaccc agggcacccc
      901 ggccgtgaag taccgcggct tcttcatcaa cgacgagaac ccggcactcg gcacctgggc
      961 ccccgcgttc ttcggcccgg ggcacgcgcc cggcttcccc aacggcttca acagcgcctt
     1021 cttcgcaaag gtcttcgagg tcatgctgcg cctgaaggcc aactacctgt ggcccgccgt
     1081 ctggggccgc gccttcgccg aggacgaccc ggagaaccac gcgaccgcca ccgcgtacgg
     1141 catcgtgatg ggcacctcgc acgaggcccc gatgatgcgc ggcatcgagg agtggaaccg
     1201 gcacgccgtc ccggccgtgc gcgacgagga cgggaacgtc gtcaccccgg gcaccgaccc
     1261 ctacggcggc accggcgagt ggagcttccg ccgcaacggc gaggcgatca agcagtactg
     1321 ggccgacggc gtccgccgca tggtcgagca ggacttcgag ggcgtggtca ccctcggcat
     1381 gcgcggcaac ggcgacgtca gcctgcccga cggcgacggc atcgatctga tgcagtccat
     1441 cctggagagc cagcgcgcca tcctcgccga ggtcaccggc acggacgacc tcaccgccat
     1501 cccgcaggta cagaccctct acaaggaggt gcagcgctac tgggaccagg gtttgcggcc
     1561 cccggacgac gtcaccgtca tcttctgcga cgacaactgg ggaaacatgc gcaaggtccc
     1621 cgagcggcgc ctcgccgaac gcgccggcgg ctacggcctg tactaccact tcgactacgt
     1681 cggcggcggg cgcaactaca agtgggtcga caccgtcaac ctggcctcca cctgggagca
     1741 gctgcacctg tcctaccgct cgggcatcga ccgcctgtgg gtcgtcaacg tgggcgacct
     1801 gaaggccgag gagatgccgc tccagttctt cctcgactac gcctgggacc ccgaacgctg
     1861 gaccatcgac cggctcgccg agtgggaacg gcagtacgcg gagcagagct tcggcccgcg
     1921 gcacgccgag gccatcgccg aggtgctgca cacctacggc gtgctccagg cccgccgcaa
     1981 gccggaactg ctcaaccgcc gcatcaccct cgacccggcc aaggacccgg ccaccgactc
     2041 ctccgccgtg gtgtacgacg accgggccac gccgttcagc atcgagcact accgcgaact
     2101 cgaccgcgtc accgaggcgt gggagcgcct cgacgccgag gcgcagcgca tcggggacga
     2161 gctggacgcg gcccaccagg acgcctacta ccagctggtg cagtaccagg tggaggccac
     2221 cgccaacctt tacgcgctgc ggcacgcgga gttcacctcg ctgcactacg ccgcgcaggg
     2281 ccgcgccgcg gccaaccagc tggccgacgc caccgacgcc aggttcgccg acgaccaggc
     2341 gatgtcggac tactacaaca acacgctggc cgacgggaag tgggccggct tccagacgca
     2401 gcccaagatc ggctacggcg acgtcgaacg gtacgggccc gacgcgccgt ggcagcagcc
     2461 gcagacgccg gaccacgtgg cgctgcccga cgaggtgttc cccccggtgc gccgcgtcga
     2521 gctgcccgag ggcccggaga tgggagtcgc gatcgacggc tccgccctgt ggtggcccgc
     2581 ggcggacacc cccgcgcggc tgccgtcgtt cagcccgttc cagagccagc ccgcgcagta
     2641 catcgaggtg ttcaaccgcg gggcggcacc gttcgcgtac cgcatcgaac cggcggagcc
     2701 ctgggtgacc gtcaccgaga gctccggcac cgtcgaaacg caggtgcgcg ccgaggtcgc
     2761 cgtggacttc gccgccgccc cgcacggcac caccacggtg ccgatcacgg tgacgggacc
     2821 ggacggcgta cgcgtcgagg tgctcgccgt ggtcgagaac cccgacgtgc cgcggcggcg
     2881 cctggccggc ttcatcgagg cgaacggcta cgtgtcgatc gaggccgcgc accactcccg
     2941 ggcggtgaac acctcgggcg tgcgctggca gcgcatcccg gacatcggcc gcacgggcga
     3001 cggcatgaca ccgttccccg tcaccgcgtc ccgccggacc ccggggggcc gggggccgcg
     3061 cctggagtac gaactgacgc tgttcaccac cggcgaggtg cgggtgtacg cctacctctc
     3121 gccgcggaac aacgtgctgc ccaccgacgg gctctcctac gccgtgtcgt tcgacgaggc
     3181 cgagccgcag accgtgaacg tcaccgaggt gaccggcgcg gacgacaccg cgatgaacaa
     3241 gcagtgggaa cgcaacacgt ccgacaacgt caacctgacg gtcaccaccc acacggtcgc
     3301 agaacctggc cgccacgtgc tgaagttctg gatggtcgac ccgacggtcg tgctccagaa
     3361 aatcgtggtg gacaccggcg gcctcaaccc cagctacctc ggccccccgg aaagcacccg
     3421 cgcacgcgac tgaccccggc ccggcccctg gcccgccacg gcgggccagg ggcctcatgg
     3481 ctcttaccgc ttcacgcgct ccacgaacac cgaccaggca ccggcgggca ccgccacgac
     3541 cgggccggga ttcttgctgt cgcggacggg cacgacgccg gggaagccgt ccgcgacctc
     3601 gacgcactcg cccccgttgt taccgctgta gctgctcccg cgccacactc cgtgcggcat
     3661 tgggtccgcg ctggtcatga ataccgctcg ttcgaaccag atcggtgcac ttgaccttcc
     3721 cgagattgcc cggaactggt cgaagacccg gtgggagcgc tacctcggcg tgaaaaagag
     3781 gctgctctgg tccgaggaga cgcgttgctg tacacggacg tcaacgaaca caacacgccc
     3841 cactcggggc gccgcgttca tcgacccggg ctgcctcgtc gtgcagctcg ttgcggccgg
     3901 gcacacagcc ccgagggcgc cgaggcgtgg accgcccgct gccgcggcct ggcgggacgc
     3961 gggccccgaa ggccgtcgac gccttcgccg ccgcctacgt gcggatgtac tggacgttcg
     4021 ccttccgccg gcccgaggag cggtggctca aggccatggc ggaagcggcc gagtcgtggg
     4081 ccaaccaccg ggggctcgtg gtggtctgaa cggtccgcgg tcgagccccg gccactcgcg
     4141 cgggagggta agcggtcggt gtgcgggtca gctcaggtgt cggcggaaga aggcggccgc
     4201 ttcgccggcc acccgggcgc ggacgggctc gccggccggt tcggcctcga agaagtcctc
     4261 gtggcgcaca tcggagccga cggatcggcc gactgcggtg gggatgtgcg ccagatacgg
     4321 gcgggtgtcg tcgtcgaacg gagtgatcgt gtccgccccg ccccaccgga tttccaccgg
     4381 gacccggacg gctttcaggc tctgcggtgt caggagagag cccacggcag gggccacctg
     4441 gaagacggcc cttatccggg agtcggacac gtccgctccc gcaccgccga tagcggcccg
     4501 cagctcgtcc gccggtacct tctcacccag cgccccgagc agatcgggga actccggcag
     4561 cgcgggcaag gacgcctgcc ccgccagcac tgccgccatg acctgcggcg cgacccgcgc
     4621 cccggccagc gccgcgacgg tgtagccgcc gagggagaag cccgccgccc ccaccggccc
     4681 caagggccgc tcaccagcca gcacgtcgag gacgaacgag acgtccctgg cccgctccca
     4741 tacgaaggcg aagccctccg gctcgtagcc gtcgacgaaa ttgttgccgt ggtggtccag
     4801 ggcgaccacc cgcagaccgg cttccgccag cgggcgggcc agccagccca tggcgcttcc
     4861 ggagccgccc gtgccgtggg agacgacgac cagcggagcg ggtgcggccg gcggacgctg
     4921 tggttcccac agatacagcc gaacgggacg cggacgggcc ggatcacgga attcgtggcg
     4981 ggatgcgtcg tgcaggagac gtgtccgcgg ctgtgtccgc ggtgagggtg ccatggccgc
     5041 atcctacgaa gaaggccgcc gccgtataag cgccggatat gggcatgatg gcgttatggg
     5101 acggatgacc gagcgccgcc gcgtggtgcg gatcagggac ggcgtgctca gcgagcgggc
     5161 cgacacgctg gtcggcgagg agccgctgga gatccgcgtc gccggccggc aggtcgcggt
     5221 cacgatgcgg acgccgggag acgacttcgc actggccgcg ggcttcctgg tcagcgaggg
     5281 cgtgttcgcg tgcgcgcagg agctggcccg catcgcctac tgcgcgggcg cgaccgagga
     5341 cggcaccaac acatacaacg tggtcgacgt gcggcccgcc gagggcatcg agctgtcagg
     5401 tctcgcactc gaccgcctgg cacgcaatgt ctacaccacc tcctcctgcg ggctgtgcgg
     5461 aaaggccagc ctggacgccg tgcgcaccac ggcccgctgg ccgctgccgc tgaccggcgg
     5521 cccgcgtctg acaccggagg tgctgagcgc cctgccggag cggctgcgcg ccgcgcagcg
     5581 cgtgttccgc agcaccggcg gactgcacgc ggcagggctg ttcacggcgg acggcggcct
     5641 gatcgacgtg cgggaggacg tggggcggca caacgcggtg gacaaggtcg tcggccgcgc
     5701 cctgacccgc ggcgcgctgc cgctcaccga cacggtgctg atggtgtcgg ggcgcgcgtc
     5761 gttcgagctg gtgcagaagg cggtgatggc gggcatcccc gtgctggccg cggtgtcggc
     5821 gccctcctcg ctcgcggtgg acctcgcggc ggagtccggg gtgacgctcg tcggcttcct
     5881 gcgcggcacc tcgatgaacg tctacgccgg ggcggaacgg ctggcgctgt ccgtctcctc
     5941 cgggccctcc gggtcatccg accagcgttt ggccaggtag gcgcagacga tcagctgcat
     6001 ctggtgaaac atcatcaggg gcagcaccgc gagcgcggcc tgcccctgga atatcacgct
     6061 cgccatgggc agccccgcgg ccagcgactt ctgcgagccc gccagcacca cgacgatccg
     6121 gtcctcgcgc ggcaggcgca ggcgccgcgc cacccacgcg gtcagcagca gcagcgccgc
     6181 gagcagcagg acctcgacgc cgaacagcgc cagcagccgc cgccagctcg cctcctgcca
     6241 cacaccggcg ttcatgccct ggctgaacgc cgcgtagacc accaccagga tcgagccgcg
     6301 gtccaccagc gacaggacgc ggcggtgccg ccggacgaag ccgccgatcc accggcgcag
     6361 cagctggcca aggaggaacg gcagcagcag ctgcccgcag atcgccagca gcgagtccgc
     6421 ggagaatccg ccgctgctgc cgatcagcac ggcggcgagc agcggcgtca ggagcacgcc
     6481 gagcacgctg gagaacgaac cggcggcgat ggccgcgggc acgttcccgc gggcgagtga
     6541 ggtcatcgcg atcgaggact gcacggtgga gggcaccagg cacaggaaca gcagcccgtc
     6601 gtacagctcg tcggtgatca gccacggcac gaggccgcgg gcggccaggc cgagcagcgg
     6661 aaagaccgcg aacgtggcgg cgagcaccgc caggtgcagc cgccaccggc gcagcccgtc
     6721 cagcgcctcg cgcgtggaca gccgggcgcc gtagaggaag aacagcaggc cgatgaagcc
     6781 cgtggccgcg ccgtccacgg cccccgccgc cgggcccgag gccggcagca gggcggcgag
     6841 ccccaccgtg ccgagcagca gcacgatgta ggggtcgagg aaacgggtca gtctgcgcac
     6901 gacggacatt gtctcccggc tccccgtgcg tgcggggcgg gggccgatca tggacgatgg
     6961 gaagcggaag atgtcggatc gaatcgacca aggactgatg tgcccgtgag cagcgtcccc
     7021 catgtgaccc tcaacaacgg cgtgaagatg ccgcagctcg gcttcggcgt ctggcaggtg
     7081 ccggacgccg acgccgaggt cgcggtcggc caggccctcg acgccgggta ccgcagtatc
     7141 gacaccgccg ccgcgtacca gaacgaggag ggcacgggcc gcgcgctcgc cgcctcgggg
     7201 ctgccccgcg aggagttgtt cgtcaccacc aagctgtgga acagcgccaa ggagacctgg
     7261 accagggacg cggtgctgcg cgagttcgac gcctcgctcg cccggctcgg cctggactac
     7321 ctggacctgt acctcgtcca ctggccgcgg ccgatgcgcg acgactacct gacgatcctg
     7381 cgcacgttcg acgagattca ccgcaccggc cgggcgcgcg ccatcggcgt ctccaacttc
     7441 aagccgccgc acctgcgccg cgtcgtcgag gagaccgggg tggtgccttc cgtcaaccag
     7501 atcgagctgc acccctacct tcagcaggcc gagaccgcga cgctcgacgc cgagctgggc
     7561 accgtcaccg aggcgtggtc gccgctcggc tcgggcaagg gtctgctcga cgacccggcg
     7621 ctgacggcga tcgcggacaa gcacggccgc actcccgccc aggtggtgct gcgctggcac
     7681 ctcacgaccg gccacgtcgc cattcccaag tccgtgacac cctcgcggat cagggagaat
     7741 ctcgacgtgt tcggcttcga tctcgacgcc gatgacatgg cggctgtcga cgccctggac
     7801 gccggggtca ggaccggccc cgatcccgac accttcgact ggaactgacc cgggcggctc
     7861 ccgggcgccc cgacgtcagc gtttcgttct ttttccgcgc ttcccacagc cccgtccgcg
     7921 ggcgtcgaat gggagcgtga ccaacgcaag gacgcaccgc acgctcgccg cgctcgccgc
     7981 gctcggcgga atcctggcgg cggtggccgg actcgccgcg ggcgagctgg ccgccgccgc
     8041 ggtgcggccg gaggccgcgc cggtcgccgc cgtcggggag gccgccatcg ccctggcccc
     8101 cgtgccggtc accacctggg cgatcgacac cttcggcacg aacgacaagc cggtgctcga
     8161 agccggcatc gtcgtggtgc tcgtgctgtt cgccgcgggc ctcggcctgc tggcgcggtg
     8221 gcaccgcgcc gcggggccgg ccggcgcggc ggcgttcggc gccgtgggcg ccctggccgc
     8281 ggtgacgggc cctggcgccc ggccgtccga cgcctggccc tcggtcgtcg ccgccgtggc
     8341 cgcggccggg gtgctcgccc tgctggccgg gcggctgcgg gcggcgcccg cgccgcggaa
     8401 cgacggcgcg gctgccgcgg agccggcggc gcccgccgac cggcgccgct tcctgacggc
     8461 cgccgccgcg accgccgccg cctcggcggg cgccgggctg ctcggccgca cgctgcactc
     8521 cgccgattcg gccgccgccg ctgcctcccg gagcgcgctg gccctgcccg cggccgacgc
     8581 agccgcgccg cccgtaccgc ccggcgcgcg gctgaacgtt cccggcctgg ccccgttcat
     8641 caccccgaac gaccgcttct accgcatcga caccgcgctg cgcgtcccgc gcgtggacgc
     8701 ggagcggtgg cggctgcgga ttcacggggc gggcgtgccg cgcccggtga cgtggacgct
     8761 ggccgacctg ttcgcgcggg agatcgtcga acgcgacatc accctcgcct gcgtgtccaa
     8821 cccggtgggc ggcaccttcg tcggcaacgc ccgctggctg ggcgtccggc tcgacggggt
     8881 gctgcgcgac gcgggcgtcc ggccgccgtc ccggggcggc ccggccgacc agttggtggc
     8941 gcactccgtg gacgggatga cgctcggcag tccgctggag acggtgatgg acggcaggga
     9001 cgcgctgctc gccttcggca tgaacggcga accgctgccg ttcgcacacg gtttcccggt
     9061 gcggatggtg gtgccgggcc tctacggcta cgtgtcggcc tgcaagtggc tgacggagct
     9121 ggagctgacc acgttcgacg cgttccccgc gtactggacg gaccgcggct gggccgaacg
     9181 ggggccggtg aagacgcagt cccgcatcga caccccgcgc ggctcggcgc cgccgcgcgc
     9241 tggcctggtg ccggtggcgg gcgtggcctg ggcgcagcac accggcatcg accgcgtgga
     9301 ggtccgggtg gacgaggggc cgtggcagga ggcggagctg gccgaggagg acacggccga
     9361 cacctggcgc cagtggcgct tcgactggcg ggccgagccg ggcgagtacc gcctccaggt
     9421 cagggccacg gaccgcggcg ggcggacgca gccggccgag gagtcgggga ccgcgcccga
     9481 cggcgcgacg ggccggcaca ccgtgaccgt ccgggtggtc gacgcgtgag ggcgcgcggg
     9541 atcagctggc accgtgtgcc ggggcgagat cctcgatgcg gcgggcgagc cgcacgtcca
     9601 gctcggtgac cttgccgccc acgctgtggg tgtgcaccgc gacgccgagc cggttgtagg
     9661 tgagcgccag atcggcgtgg tggtccagct cctcctgcac ggtcgcgatg tgcacgagca
     9721 gcgcgacggc gggcaggtgg ccggccaggc cgtagctgcg caccagccgg tcgtcctcca
     9781 gggtccagcc gggcagcccg gcgagcgcct gctcgatctc ctgcccggtc aacggccgcg
     9841 gtgccatggc gtgctccctc cgtacggcga ggtacaccag cctaggtccc gcgcgccgcc
     9901 gcggcacgtg gaccttcgga cgccggctcc gcgtatctcg gtccgtaccg tgatgtgccg
     9961 ccccgccgcc ttggacacca tgggtgccgg aggtgctggc atgacctttc ggatcaccaa
    10021 ggagtttcac ttctcggcca gtcaccggct cgacgggctg cccgaggggc acccgtgcgg
    10081 ccggctgcac ggccacaact acgtggtgga gctggagctc gccgcggcgg cggacgggct
    10141 ggacgaggtc ggcttcgtgc gggactacgg cgagctgaag gacttcagcc ggtggctgga
    10201 ccacgaggtg gaccaccgcc acctcaacga cctgctggcc gaccgcaatc cgtcggccga
    10261 gaacctctcg cgctggctgt acgaacgctg gctgccgcgc tatcccgagc tgagctccgt
    10321 ccgggtctcc gagacggcga agacgtgggc ggagtaccgc ccgtgacggc cgcacccacg
    10381 gcaggccgcg aagggggtgg tgccgcaatg ggtccgaagc tcatcgtcaa cgagatcttc
    10441 ggcccgacct gaccgtgcag ggagaaggcc cttcgatggg ccggcgctgc gcgttcctcc
    10501 ggctgggcgg ctgcaacctg gcctgccgct ggtgcgacac cccctacacg tgggactgga
    10561 ccggcatcgg cgactccggg gtggcgtacg acccgcgcac ggagctgcgt gcgatggcct
    10621 gggaggaggt cctgcggcgc ctgcgcgcgt acgcggtgcc gatgatcgtg atctccggcg
    10681 gggagccgct cagccagcag aagcggctgg tgccgctgct gcgcgcgctc gccgggagcg
    10741 ggcaccgcat cgagatcgag accaacggaa ccgtcacgcc gcggccggag ctggttgagc
    10801 tggtgcggtt caacgtctcg cccaagctgg cccattcggg cgacccggag tcgcgacggc
    10861 tcaaaccgga agcgctcgcc gcgctcgccg cggcgcccgg caccgcgttc aagttcgtct
    10921 gccggacccc cggggatctg gacgaggtgg ccgccgtcgt cgaacgcttc ggcaccaccc
    10981 cggtgtggat catgcccgag ggacggaacc gcgaggagct ggaccgcaat ctcggcacgc
    11041 tgggcgacga ggtgatcgcc cgcggctgga acctgacgac ccgactgcac atcgcggtat
    11101 ggggcaaccg gaggggcatc tgatgaccac gagtgcctac gagaaccggc cggaaaccca
    11161 cgacccgctg gaggacgtgg cacgtcggct tctcgtcgag atcggcgagg acccggaccg
    11221 ggacgggctg aaggagaccc cggcgcggtt cgcccgctgg tggcgggagt tcagtgggta
    11281 cgacgcgggc gaggcggaca cccgtttccc gttacgcacc agcggacaga tcgtgatggt
    11341 ctccgacatt cacgtctggt cgctgtgcga gcaccacctg ctgccgttct cctgcgtcct
    11401 gaccatcgcc tacaagccgc acggcgacgt gctcggcctg tcgaagttcg cgcgcatcgc
    11461 ccaccgccac gcgcaccggc tccaggtgca ggagcgcctg atccaggacg tcgccgagga
    11521 cgtctccgcc gcgaccggct ccccggacgt cgcggtgatc gggcagggcg agcacctgtg
    11581 catgagcatg cggggcatcc gcaccccggc cctgatgacg acctcggtgt tcaccgggat
    11641 cttcgaggag tacgggccgg cccgcgacga gctggtcgcc accgccttcc cccgccgatg
    11701 aggcccggcc gagaaaggag catgccgtga acatcgctct cgtcctgctg acctacaacc
    11761 ccgacgagcc cgccggcgtg gaacgtgccg tcgcctcgct cgccgacggc ctgcgcgagc
    11821 tgggtcaccg cgcggtgatc atcgccgcgg gtccggccgg cgaggacgac gacgagaacc
    11881 tgctgcggct gcccacgctg aacctgccgc ggccggtcca gttcgacgag gagcagcggc
    11941 tgctgaccga gcacgagccg ctccggcggg agatcctgac cctgctcgat cagcaccgga
    12001 tcgacgtggt ctgctggagc gacgccgtgg tgggcctggg cttcctgagc ccggcaccgg
    12061 ccgaggtgcg gacggcgctg atggtccact tcctgcgcgt cgacgagccc atgcgggaga
    12121 gcctggccca cggccccgac gccgtactcg ccgtcagtcc gttcatgatc gaggaggcag
    12181 ccagggccgg gctcgactcc agcggctggc acgcgttgcc caacgccctg ctgggcgtcg
    12241 gcgagccgcc gccgcccgag gaacgcgaac ggctccggcg cacaggaccg gtgcgggtcg
    12301 tggctcgtgc cgatccgtcc aagggcgtcg ccgaactgct gcgggcccac ccggacggat
    12361 gggggcgccc cgtgcaggtc gtgctggcgg cggccgggtt cgagctgtgg ccgggcatgc
    12421 aggacgacgt gttcgaggaa tgccgggccc tcgccgggaa ccggccggac atcgagatcc
    12481 tgcccccgct cgcctgggac gaggtgcagc cgttcctcgc gggcgccgcc gtcaccctgg
    12541 tcccgtcgac cagcccggag acgttcggca atgtccccgc cgagtccctg tcggtgggca
    12601 cgcccgtcgt cggctacggc ttcgggcacc tgcccgcgct cgccggcccg gccgggcggc
    12661 tggtcggcct ggacgtggtg agcggcttcg gccacttgcc cgcgctcacc ggccgggcgc
    12721 tcgacatggt cgacttcgcg gaggggccca agcggctgtg ggaggccacc gcggacctgc
    12781 tcgcggaccg tgaggcgtat cacgccgcgg cgcggcaggc gccccaccag gtcgccgagc
    12841 acacgccggc cgccgtggcg gcggccttcc tgcgcgccac gctgggcacg gcgtgaacgg
    12901 tgggccgcgg atctgcgtcg tgatccccac ctacgagcgt gccgcgctgc tgcgcggcac
    12961 gctcgacgcg ctggccgggc agcggctgcc gacggccgag ttcgaggtcg tggtctcgga
    13021 cgacggctcc cacgacgaca cccgggaggt ggtggcgggc ttcgccgacc ggctttcgat
    13081 ccggtaccgc ttccaggagg acctggggtt ccgggccgcc gccgcccgca acgcgggcgc
    13141 gcggctggcg tccgcgccgg tcctggcctt cgtcgatgcg ggcatcctgc cgggcccgga
    13201 cttcctcgcc gcccacctcg ccgcccacct cgccgtgccg gagggggctg cccaggaccc
    13261 gccgcgggcg gtgatcggtt acaccttcgg gtaccggccc ggtagcccga ccccggggct
    13321 cggcgacgcc gtccgggtca tgaccccgga ggagctggtc ggccactacg gcgacgcgcc
    13381 ggacttccgg gacgcccggc atctggcgtt cgcccgcttc gggttcgacc tggggcgcag
    13441 tgccgtgccg tggcagtggt tctggtcgat gaactgctcg gtgcgcgccg acgacttcct
    13501 ggcactcggc ggcttcgacg agagcttccg cagctggggc ggtgaggacc tggagctggg
    13561 gttccggctg ttccggcacg gggtgcgccc ggtggtcagc agggacgcct gggccgtgga
    13621 cgtgccgcat ccgagggccg cctcggcgga cctggcgagc aaccacgcca acttcctggc
    13681 cttcctgcac aagcacccgg agccggtggt cgagctgctg tgggcgtggt tcgcgcgcga
    13741 gcggcccggc ttcgaggtcc ggcacgactg gaacaccgag gacgagtacc tgctcctgct
    13801 cgacgcggcc gccgcggccg ggtctgtcga cgtcacgcgg gagttggccc cactgcggga
    13861 cgtcgccccc ggcacgcgga tcgccgtcct cggctgcggg gcgtcgattc ccccctggct
    13921 gccgcgggcg gagctgttcg acttcgaccg gcatgcggtg aacgccgccg cgcggtccgg
    13981 gcgttcggtc cgccacgcga tcggcctgcg cacgacgctg ccggacgact cgttcgacat
    14041 cgtcctcgtc acctcgcggc tgaaggacct gtggagccgc tggcggccgc agttgctcgc
    14101 ggaggcccgc cggatcggcg gggacctccg cgggccactg tccggatgac gtcgggggtg
    14161 tcagccgggg cggacggcgt ggacgaggaa ggtcctgacg tcctccggga tcagcggtga
    14221 cggccgggcg tcgaccacga agccgtgtcc gcgcagcagg tcaccgatcg cgtcgagccg
    14281 gccgtccagg tcctgcacct caaggaccag ccggccgatg agcggccagt gctcggtgtc
    14341 gactccgcgc agcacgtcca gctccgcgcc ttcgacgtcg atcttcagca gatcgacccg
    14401 ctcgccgggg accaggtagg acgagagccg cgccacctgg acgggtacgg agtagccccg
    14461 gtagtgcgcc ctgatgtact cctccggggc ctcccgggcg agcacggcga tctgcagctc
    14521 cttctcctcc gggtaccgcg tcgaattgcc gggcgcctgc gggtagtaga cgaagggcac
    14581 ctcgtcctcg gtgcccgagc cgagggcgca ctcctcgatc gtgatgccgg tcagcccgtg
    14641 cgcctcgatg ttgcgccgca gcgacgccag cgcttccggc atcggctcga aggcgcggac
    14701 gcgggcggtg gggcaaccgc gtttgaggaa gtacgtgaag aggccgatgt tcgcccccac
    14761 gtcgatgacg tacgccccgg ggggcagccg gatgccgctg tagcagccga gcttgaatat
    14821 ctcctcgtac tgccagtggg cttcggcctc gtggggggcc cagaagtcca gacccgtgtc
    14881 gagtgtgatg ttccgtatac cagtcacatg cgtacctttt gctgatcgca cgccttcggg
    14941 cgtgctcggt cagggaacgg cgaaccgggt cacgccgtcc aggtaggtcg tcgggtccgg
    15001 cagtccggct tcctcgaacg cctcccgccg ctcgtagcag gtcccgcaga tgccgcagtg
    15061 ctggtcgccg cccttgtagc acgaccagct gcgccccagc ggcgctccga gcccggcccc
    15121 gtgggcggct atcgcggcct tggtccaggt caggaacggc gcctcgaccc tgggcgtggg
    15181 gaaaccctcg ttggccacgg cgaccagctc ctgaagggcc gtcaggaaag gcgggcggca
    15241 gtccgggtag acggcgcggt cgccggcgtg catgccgagc gccaccacgc cggcccggca
    15301 ggcgacaccg accgacacgg cgatgttggc gagtaccgca ttccggttcg gcacgaccgt
    15361 cgccttcatc gcctcctccg cgtagtggcc ttcggggacc gcgacgctct cgtcggtgag
    15421 cgccgatccg gcgagcagcg aaccgaagcc gctgaagtcg acaagccggt gggcggcgcc
    15481 gtagtgggcc gcgatgtcac gggcggcgtc gatctcccgg cggtgccgct gcccgtagtc
    15541 cacggtcacg gccacgaggc ggaaccgcag cgccgcgtag tgcgccatca gggcggtgga
    15601 gtccatgcct ccggagagga ccacgacggc ggtgaacggg tccgggctgc tggtgtcttg
    15661 ctccatcagg gaacctccca ggatcggtcc ggcctgtccg ttcagtgtgg tgccggaccg
    15721 gcgcgcgcac atcacggccc gaggccgaag gattgagggc ttccggccga agcacggccc
    15781 cgcgccccgg tgaccgcggg cctcggtgcc gccgggtgcc ggcgggcggc cagggccccg
    15841 tcggtgagga gggtccacag gccggggttg cagaacacca gggggaagtc gccgcgtccg
    15901 tcgatacgaa gcttgcggta ggcgctggaa aggtgcagtt cgacggtgcg ccgggtgatc
    15961 tgacgcatcg tcgcgatccg cttgttcgtc agaccgcgca tcgcgtcgac gaggatctgc
    16021 cgttcgcgcc gggtcagcgc caggatgccg cgcaacgaga cgtgctgagg cgcgcgttcg
    16081 tccgccgcga gcagctgctg cccgagctgg ccgctcagcg cgcgggcctc gcaccggtcg
    16141 gccagccgca ccgctcgggt caggacggcg agcgcctcgt ccggccggtc gagccggatc
    16201 agcaggcagc caagatcgcc gagcgcgtgg gccaggtcat aggtgtcctg cgtgttctcc
    16261 agcagcgaca ccgcctcgtt cagcaggtgt tcgcccgccg tgccgccctc cacccggccc
    16321 agcacgcgca gggcccggcc gcgttccccg gccgacccgg tgctgccggc gaaccgcacc
    16381 tgctggcggg ccagttgcct ggcctcctcg gtccggccca cctggtcgag cagcgcgacc
    16441 ccgtgcatgc gccacgagac ggtccccgtc gcccgcaggc cggcgtccct gccgcgctcc
    16501 agcagctccg ccatgtcccg tccggcgccc acgagatcgc ttccggcggc ccgcaacctg
    16561 gccctggcca gcaggagatc ctgatagtgc cagccgggcg gcagctctcc cagatatccg
    16621 tgccgccgca gcagcgcctc ggcctcggcg ccctcgtcca ggctgaggag cacaccggcc
    16681 aggagaccca ccgtgcacac cagcacgggg tcgctcgcgg ccgccccgta tccggcggtt
    16741 cgttccagag cggcggcgag ccgcccgcgg gcggtcggca cctcccccgc ggccagcgcg
    16801 atccgtgcct cgaccagcag cagcatcgcg cgggatgcgc tcggccagcc ctgcgcgaag
    16861 ccgtcgagcc ggcgcacgtg ggcggcggcc tcgtcgtggt ggcccgactc cccgagcacg
    16921 gtcagggccg agggcaacgc caggggatgc aggcccagtt cgtcgaggct tcggcccagc
    16981 gcccagcgcg cccgccgcac ggcggcgcgc ggatcgtcgt cgacgaggaa gcggcagaac
    17041 gcgccgatgg ccgtcgccgc cgcgtgcgtt cgcggcacgc cgtcgcggcc ggccgacggc
    17101 ggccggcccg gcagatcctc gatgatcttc gcggtgtccg cgggcggcga ctcgtagaag
    17161 tgcgtcagac agcggtggag gtggggccag ccgtgcagcg gggtcccgtc gaccagcgcc
    17221 gccacctggt caggcacccg ctgcgcggcc tcgggcaggc ccgcgccgtc cagggcccgg
    17281 ccgatatggc cgagcagacg ggcccgggtg acgtggtcgg tggcgcgggc cagcatgtcc
    17341 accgccgcgc cgagaccggc ggccgggtcg gcccggaccc gcgccgctgc cagctccagc
    17401 atggcgacgc ggtgctcctc accggcagcg gtcctgacgg cgagttcgag atagcgcaac
    17461 gcggtggcgt cctcggcgga acgggcggcc cgcagcagtg cgcccaccgg ccaggcgccg
    17521 ccgggcggca ccgtcgaggc gatgaggtgg tcggcgatcc actccgccgg ggcgccccgc
    17581 tcgtgcaggt aggcggcgat ggtgaggtgt gccgcgttgc gcgccatgag cgtcatggcg
    17641 ccgagcagcg actgcgccag cagggggtgc cgcagccgca gggagtcctc gtccgccacg
    17701 agccgcatcc gcaccaggag atcaagggcg ttgagggtcc tgctcagccc gattccgctc
    17761 agatgcgcga cgagggaggt gtccgcgccg ccgcggccgg cggcgacggc gatggcctcc
    17821 gcgacgcgcc cggcgtccgc gtcgatccgg gcgacgcgcc ccctcaccag ctccgccacc
    17881 tcgggcagca ccgcgctctc gggcactacc ggcccccggg cggcgcgaag gccgtcccgg
    17941 acccagccgg ccagttcgca gatcagcaac gggttgcctg cggtcagccg atggcaggcg
    18001 ccgaccagtc ccgccgtggg gacgcgcggc agcagtgcac gcatcagcag ggccgtctcc
    18061 cgctcggaga gcccgtccag cgccagctgc cgcgcgtcca gtaataactc ggccagctcc
    18121 ggcggggcct cggcgggctc gcccggccgc accgacacga ccacgaccac ggggaggtgg
    18181 gcacacgtct ccagcaccag ctgaagcgct gccagcgccc cggggccggc ccggcagacg
    18241 tcgtccaccg tcaggaccag cggtgcccgc gccgccagca cggtgaccgc gctcagcaca
    18301 gtcggccaca gcgccggtcc ccggcccggg ccggggacgg ccgagcagaa gtcctcggcc
    18361 ccgagccgtt cctggacgct gcgaagccgc gtctgtggct cgctgcccgc cgggagggcg
    18421 tcggccagcg ccaggaccag ctcctcgacc agcgcgcctg ggacgtgccg gtcccgccgc
    18481 cggccgacga gtcctaccgt ggtgctcccc tcggcgcgcg cggcacgggc gaacgcgccg
    18541 agcagcgcgg tgcgccccgc gcccggctcc ccggtgacca cgcaccggac cagccccttt
    18601 tccggacagt cccgccgggc gcggcccagc gcgcgcagct gcgcctcccg gcccacgaac
    18661 gcggggggcc gcgggcgggc ccggcccgtc acgagggtgc tcccggccgg gcgacgagga
    18721 cggttccctg gtcgccgatc gcgtgcgggc ggcgttcgaa gtgtccgcgc accgccggcc
    18781 gcagagcgct ccgcatatcc gccgctcgcg gatgcccttc gtaccagaag tcgaccagca
    18841 ccgtgcacgc cgcgtcgatc cgctcctcca gggaaatctc cggaaaatgc agtgcggact
    18901 cggtccgctg gagcgcgaag cggcgaaatc cttcctccgc gagaatctcg gcggcagtga
    18961 cgagaaggaa accatggtga tcgtacggct cgcccgcgat gggcgcgcag acctcgttga
    19021 ggatattgat cagctcattg tccggggctc cgccgatcag caggattctg gctccgggat
    19081 cggaaaggtc acacacgcgc gccatctcgc gaacggacct ttgcagatcg tccacaaagg
    19141 gcaggaccca ggtggagaac accacgtcga aggacgcgtc ggggaacggc agtgattccg
    19201 cgcgaccggg gaacgcctcg atgacaccgg ccccttccgc ctccgtggcg aggtggagcg
    19261 tggcgacccg gtcgcggtgc ggctcgacgg tggtgcagcg gcccgactcg gccgcgacgg
    19321 cccgggtgag ctcccccgtc ccgccgccga cgtccaatat tcgccgtcca ccggcggtgg
    19381 cggcacggac caggtcgatc tcctcgccgc gcccgagccg ctgcacgaag ttcagccatc
    19441 cgtcgcggcc gaggcggcgc gggccccggt actcggcggg catacggtcc agcgggccgc
    19501 acaacgggtg cgtgcggatg gcgttttcgt cgagatgcgg catcactgca ctcccggagt
    19561 tttgcgtgtt cacggtattc ccctcggatg ggctgcggac gtggccgccc cggcacgaag
    19621 tatgcggcca gggggcttgt cgccgtttcg gcgaggctat gcgcgtccgc gaactggcag
    19681 ggtttcggaa ggatgcccga ggcgcggacc tcttcgtctc gcgcaggcac aggccctacg
    19741 tggatggaat gaccgaacgg gtaagctccc gttaaccttt ggcgacatcg tccccatcgg
    19801 gataacgttt tacctccggc cgcaccgtac cacccagttg gcatattcgg gaggggagat
    19861 acccgctgcc ctggggttcg gcaaggctcc gatccagcca ttcaatcgcg cacgccgacc
    19921 ggcacagaaa gagaccggaa tccgtctgat ccagaccgga atccgtctga tccacgaagc
    19981 tccgaacgac actgcctagc ggggccggga aggcgcgtgg gccggttgcg cgggggtggg
    20041 gcggagcatt gcctcccgct gccagcgcag cagttcgcgg tgcaccgcct ccgcgcccac
    20101 gaggccgggg gccggggcgg acagagccag cggggacatc aggaaggcgc ggctctgctc
    20161 cccgccgagg ccgccgtggc agccgatctg gtcctcgaag gcgtgcacgt cgccggtgtc
    20221 ctgatccacc gaggagttga ccatgatgtc ggcggcgtgc gcgaagcccg cggtgcggcg
    20281 cacggccgcg gcggcccgcg gtccgaaggg cgccagcggg tcgtggccga cgatctcgcc
    20341 ggtggtgagc cggtgttcgg cgccgcccgc gccgaggacg acgggcccgt gccgttcgtc
    20401 gtggacgagc aggaagccga tgcccgggtg ttcggcgagc gtgcgcagca gcgcggggca
    20461 gcggcgttcg atggtccggc gcccggcccg tcccggcacg tcgggcaggg agatcaggcc
    20521 gaggttgccg gaggcgagga cgacgggcgc gcgcccgcgc tcctgccggt cgtcctccgc
    20581 gggccgcggc cgggcgggcc gttccggccg gtggagcgcg acgcgggcgg cgccgcgggc
    20641 ctcggcgccg gtctcctggc ggcgcggcgg cctgggcacg ggccgcccgc agccgatcct
    20701 gaccagctcc tccagcgtgt gcccgtaggc ggcctcgaag gtctcgccgt ggctctgccc
    20761 gtggtcggac agcagcacca ggtggtaggg gcggggcgcg tgctcgacgg cgcggaggat
    20821 cgtggcgacg cagcggtcga ggcgcgcgag caccggccgg gtgtcgcggc tgtcgggacc
    20881 cgagtggtgg gcgacctcgt cgtaggcgac gaggtcggcg tagacggagg tgcggccgtt
    20941 gaggacgtcg cctatgacgg cggcggtgac cacgtcgcgc tggacgacgg tggcgaaggc
    21001 gcggatgaac gggtagaggc cgccgcggct gacccgcggc ccgctgccgg tgagccgggc
    21061 gcgcagggcc tgcgcgatct cgcggaccag ctcggcgagg aaggaggcgg cggtgcgcgc
    21121 ggcgtgggcg gggtcggaga agtacgcgaa gtacccggcg cgcgagcgct gcccgcgacc
    21181 gcgccgcgcg gcgacggaca gcaccagcgc ggcctggccc gcgccgccgg tgaacaggtt
    21241 cccgcggctc gcgccgtcct gcgcgagcag gccggcgctg ccggtgcgtt cgacggcgcg
    21301 gcgctggagt tccgcggcgc ttgaggggcg gttgctgacg atgacctcgc cggtgtcctt
    21361 ctcgtaccag cggaacgcgg gcacatcctc gttgctgccg tggaggatgg ccagctgggc
    21421 ggcgccggtc tggctcgacc agtcggtgtg ccagggcgtc agccggtggg tggtgccgag
    21481 gagggcggcg agggccggca tctggggccg ttcgccctcg agcgcgtcgc acagccgccg
    21541 gtggccgatg ccgtcgagct ggaggaacac gatgccgggg gtatcggtgt gccgggccgt
    21601 gcccgagcgg gcggcccggc ggccggccat ccggcgcagg cggcgggcct gcgcgtccgg
    21661 gtcgcggacg gcgaggaagg tgctggtggc ggaggcggcg acggacatca cggccgccac
    21721 gacgacggca gtcgacggcc cggcggtgcc gcggccgtcg gggatggcgc tgagcgcgag
    21781 ccacagcagg gagccgttga gcaggaagac cagcaggccg agggccaggg cgggcaccag
    21841 cagcatcgcg cggaccagcc agggccagac cagcgcgttg agcaggccga agcagccggc
    21901 gccgagggcg gcggtgatgc cgatgcgggt gaagctgtcg ccgtcggcgg actggaggtg
    21961 gaagccgggc agcaccagcg cgagcagcac catggtgagg gtgctcaccg cccacacggc
    22021 gagcacgcgc agcagggccg cacccgcgtt ccgccaggtt gtcaccggta ccgacctgcc
    22081 cttcttccgg tctgccattt tccacgtcgg ccgcctggca tcctgggagg acggggaacg
    22141 ggccgggggg cgggagcgga aggagttcca cgtgccggtg gacatcacct ggtgggggca
    22201 cgccaccgcg acggtactcg actccgggac ctcggtgctg accgatccgc tgttcacccg
    22261 gaggtgcgcc cacctgcgcc ggcggcgcgg gacgctgccc ccggtggccg ccaggcgcgc
    22321 ggacgtggtc ctcgtctcgc acctgcacgc cgaccacctg cacctgcgtt ccctcgcgcg
    22381 cctcgccgcg ggcacgccgc tgctgctgcc gcgcggcgcg ctgcgggcgg tgccggggct
    22441 gcggcggctc gcggcccgcc ttgaggtgtg cgaggtcacg cctggcgacc gggtgccggt
    22501 gggcggtctc acggtgcggg cggtgccggc cgcgcacgac gggcggcggc tgccgttcgg
    22561 gccgcggcgg gtgtcggcgc tcggctacgt ggtggagggg gaggcgcgga cgtactacgc
    22621 gggggacacg gatctgttcg aggcgatggc gcgggaggcg gggcccgtgg acatggtgct
    22681 gctgccggtc ggcggctggg ggccgcggct ggggaacggg catctgaacg cggagcgggc
    22741 ggcggaggcg ctgacccggc tgcgcccgcg cggcgcggtg ccggtgcact acggcacgta
    22801 ctggccgttc gggatggcgg gggtgcgccc gcacgagttc cactcccccg gtgacgagtt
    22861 cgtgcggcac gcggcccggc tggccccggc ggtgcgggtg caccggctgc ggcacggcga
    22921 gagcgtgcgg ctggcggtgg ccggatgacg acggcgggcg cggagtgcgc gctcgccgcc
    22981 tcacgggcgg tgtccccgga tacgacgcag caggcgatcg gctacccgtc gctgttcctg
    23041 ctggtgctgc tgggggcgct ggtgccggtg gtgccgacgg gcgcggtggt cagctcggcg
    23101 gcggcggtcg cgttccacca cagcaacgcg gcggcgttct cgctcggggt gttcgcggtg
    23161 gccgccgcgg cggcgttcct cggcgacgcg atcctgtacg cgctgggcgg gcgcggggtg
    23221 cggtcgcgga acgggtcgcg ctggctggac cggatacgcg agcaggtggc gcccgagccg
    23281 ctggcgcggg cgcaggagcg gctggcgcgg cggggcgcga cggtgctgct ggtgtcgcgg
    23341 ctcgtcccgg ccggccgcat acccgtgatg ctggcctgcc tcctggcgcg catgcccctg
    23401 caccgctacc tgcgcggcaa tctgcccgcg gtgctcggct gggcggcgac ctaccagctg
    23461 ctggggatgc tgggcggcgc gctgttcccg catccgtggc agggcgtggt cgccgcggtg
    23521 acgctcacgc tgctgatcgc ggcggcgccg gtggtcctgc gccgtctgcg gcaggccctc
    23581 ggccggccgg cggcgggccg gccgcgcccg gcgcgtgggc ttcgcgggcg cggatgatct
    23641 cgggcagccg ggccgcgatg acgtcgatca tggtccgcag cggcgcggtg agctcccggc
    23701 cgatgtccgt gagggcgtag ctgacccgca ccggcacgac gggctcgacc cggcgggtga
    23761 tcagcccgtc ctcggtcagg acccgcaggt tctgcgagag catcttctcg ctgatgccgc
    23821 cgatgcggtc gcgcagctgg tagaagcgca gcggctcctc ccgcagcgcg acgagaacga
    23881 gcactcccca gcggctggtc acgtggtcga ggaccgtgcg cgtcgggcag tcgcgcacga
    23941 acacgtcgtc ggcaccgtcg gcctgcggtc ctacgttcat gacgtgacct taccaaaagg
    24001 tatgccctta ccaggggtta gccgcatgtc ctagggtgag cctatgagcg agatcacggt
    24061 ggaggtctgg tcggacctcg tctgcccctg gtgctatatc ggcaagcgac gcctggagcg
    24121 ggcgctcgcc gacttcgacg gccgggacga ggtgcgggtg gtgtggcgca gctaccagct
    24181 ggacccggag gcgcccgcca cggcggacct gacgctgccc gcccacctga ccgagcgaca
    24241 gggcctgccc cccgagcagg tcgcggagat gctggggcgg gtcaccggga tagccgaggg
    24301 cgacgggctc gcctaccggc tggcggaggc cagaccggcg aacaccttcg acgcgcaccg
    24361 tctcgtccac cacgccgcgg gcctcggcct cggtgccgcg gtgcaggaac ggctgctggc
    24421 cgcctacgcg caggagggca ttgcgctcgc cggacacgag accctggcgc ggctggccgc
    24481 ggaggccggc tgcgacgagg cggcggcgcg gcgcgcgctg gcgaacgggg accacgccga
    24541 cgccgtgcgc gaggacatcg cgaccgcccg gcagctcggc atcaccggcg tccccgcctt
    24601 cgtcctcgac cgcgccttcc tggtctcggg cgcacagccg gcggaggcgt tcggccgggt
    24661 cctgcgcgag ctgcacacgc gcggcgcggc gtaggccgac aggactcccg ggctcagggc
    24721 ccttccggtg gacagggcgc gtccagcagc cgcgagccgc cgaccgggag gtcccacagg
    24781 tcggccgccg ggcggccggc ggcctgccag gcggcgcgca cccgggccag cggctcggtc
    24841 ggcggctcgg cggagagcag gaacgtcgcc cagtgcatcg gcgccatccg cgccgccccc
    24901 aggtccccgc aggcgcgcac cgcctcctcc gggtcggtgt gcacggggcg ctggagccac
    24961 ggcgggtcgt aggcgccgat gggcagcagc gccaggtcga tgccgggaca gcgggcgccg
    25021 atctcggtga accagtgccc gtagccggtg tcccccgcga agtacagccg ccgcccggcg
    25081 gcgtcggtca gcacccaacc gccccacagc gaacggcagg tgtcggtcag cgtgcgcttg
    25141 gaccagtggt gtgcgggcac gaagtcgaag cgcacgggac cgccgggggc gggcagttcg
    25201 gccgcctccc accagtcgag ttcggtgacg cggcggaacc cgcggcgccg gcaccaggcg
    25261 ccgagcccgg cgggcacgaa cagcggggtg cggcgcggca ggcgtttcag ggtgggcgcg
    25321 tcgaggtggt cgtagtggtt gtgcgagatg acgacggcgt cgacgggcgg caggtcctcc
    25381 caggcgacgc cgaccggggt gatgcgggcg ggggtggcca gaatccggcg cgaccacacc
    25441 gggtcggtga gcacggtcag gccgccgacg ccgacgaccc agctcgcgtg gcccgcccag
    25501 gtcagggaca gctcccccgg gccgggccgc ggcagcggcg ccggggcgaa cgggaggccc
    25561 gcagtgtcgg ccggcgcggc ggcgcccggc cgcagcgacc cgctgcgcga agcgcggatc
    25621 agcgtgacca ggccgggcag cggcgtggtg aggcggtcgg cgaagc
//
