LOCUS       NZ_LZNS01000001        24315 bp    DNA     linear   CON 15-JUL-2024
DEFINITION  Streptomyces sp. MP131-18 scaf_01, whole genome shotgun sequence.
ACCESSION   NZ_LZNS01000001
VERSION     NZ_LZNS01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. MP131-18
  ORGANISM  Streptomyces sp. MP131-18
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7861428)
  AUTHORS   Paulus,C., Rebets,Y., Tokovenko,B., Nadmid,S., Terekhova,L.P.,
            Myronovskyi,M., Zotchev,S.B., Rueckert,C., Kalinowski,J. and
            Luzhetskyy,A.
  TITLE     New natural products identified by combined genomics-metabolomics
            profiling of marine Streptomyces sp. MP131-18
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7861428)
  AUTHORS   Tokovenko,B. and Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2016) Helmholtz Institute for Pharmaceutical
            Research Saarland, Helmholtz Centre for Infection Research, Campus
            C2.3, Saarbrucken 66123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 72x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001984575.1-RS_2024_07_15
            Annotation Date                   :: 07/15/2024 02:52:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,130
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 6,890
            CDSs (with protein)               :: 6,890
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 179
            CDSs (without protein)            :: 179
            Pseudo Genes (ambiguous residues) :: 0 of 179
            Pseudo Genes (frameshifted)       :: 62 of 179
            Pseudo Genes (incomplete)         :: 155 of 179
            Pseudo Genes (internal stop)      :: 7 of 179
            Pseudo Genes (multiple problems)  :: 45 of 179
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:18:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 808537
            Orig. end                         :: 832852
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LZNS01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24315
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24315
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24315
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14315](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14315)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    482..500
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.26"
                     /tool="antismash"
     misc_feature    519..536
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.3"
                     /tool="antismash"
     gene            618..1430
                     /locus_tag="STBA_RS03500"
                     /old_locus_tag="STBA_07030"
     CDS             618..1430
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010475057.1"
                     /locus_tag="STBA_RS03500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07030"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_077057825.1"
                     /transl_table=11
                     /translation="MERSAWAQPGIDPSVPSLSRMYDFYLGGSHNFEADRAAAREAIAA
                     FPGLPALALANRAFLRRAVRYAVAEGVSQFVDIGSGILTFGNVHEIARRTGDDTRVVYV
                     DNDPVTVAHSRAVLAGDDRTDILAADLRGPSAILNSEQVGRLIDLGRPVALLLVAVMHF
                     LGEDDKPHERIAELRDMLAPGSLLALTHASPEHRPTASVPDARISEVYRRAGATLVLRS
                     GAEITHFFEGFDLVPPGVVPLPDWRPDGPPDEEGPKVNSGFAGVGRKG"
     gene            1427..3604
                     /locus_tag="STBA_RS03505"
                     /old_locus_tag="STBA_07040"
     CDS             1427..3604
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432667.1"
                     /locus_tag="STBA_RS03505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07040"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_077057826.1"
                     /transl_table=11
                     /translation="MTSSPTGPTGHHRTGDSTEPSDGLRRFAALWCRAVHPRAATPLSR
                     PEFEALLLGLARRLADALRAPRFDPAPGHAVGAALVAAHCTSPDALPGILAVIDSHLVA
                     HCGPTDGEAGPDASESRARCTRLQHAVSAGFARALQERTRSEQEALSRAALAAQTEMAD
                     ALHESEARFRAVFKGAALGIGIADMDGTILDVNDALNQMFGGSEQHIRHRNVLDWARPG
                     DHPEAGRMLEELMRGEREHYQVEKSYPRDDGTTLWTNLTVSLLRDASGEPRYMLAMTED
                     VSERRLLNLRLRYQATHDALTDLPNRSLFFERLEQALDRSGSGPARIGLCYLDLDGFKA
                     VNDSLGHAVGDQLLIAVAERLQGCASGPGQMLARIGGDEFVALVADPPEPRAVTELAER
                     ALEALATPVEVGGRELLVRASIGVVEGATRHLTSAEVLRSADITMYRAKAEGGNRYALA
                     DPDSDARAISRHHLTHHLPAALKGCEFFIEYQPLVKMEDGSIEGAEALVRWSHPRHGVL
                     GPDRFIPLAEHTGLIVPLGRWVLEEAVRQACQWQVRGIGGARPLKINVNLSPRQLHHPE
                     LVADTIAVLEEAGLEPSSLCLEVTETAMIKADENELRPLRELAEYGVGIALDDFGTGYS
                     NLANLRRLPADTLKLDRSFTQGLQRDPADPVDLKIVEGIVSLAHTLQLSVTVEGVETSA
                     QAEQLRELGCDSAQGWFYARPGPPERLPEAV"
     gene            complement(3622..4788)
                     /locus_tag="STBA_RS03510"
                     /old_locus_tag="STBA_07050"
     CDS             complement(3622..4788)
                     /EC_number="2.7.1.170"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031767.1"
                     /locus_tag="STBA_RS03510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07050"
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="WP_077063080.1"
                     /transl_table=11
                     /translation="MLSGTSYDAVDAAVAELAFEGTDLCLRPRGLHTEPYPAALRGELA
                     GCLPPAATTLERVCRLDTGLGQFFGEVAARADAALAGGRADLVVSHGQTVYHWVADARA
                     RGTLQLGAAAWIAEATGLPVVSDLRTRDIARGGQGAPLAALLDALLILDEAPGAPARGA
                     LNLGGIANITARGADGGVLAYDLGPANALIDAAVTEASGGAECMDTGGARAARGTVDAG
                     LLDALLDEPYYRLPPPKSTGKELFHADYLGTRLRAVGRRPATDDLVATLTELTARLVAA
                     ACREHALTELVVSGGGVRNPVLMDRLRALAAPAALVPPERFGLPAQAKEAYLFALLGFL
                     TVHGLAGSVPSATGAGGPAVLGSLTPGAAPLRLPAPRTAPPRRLRIVT"
     gene            4953..6689
                     /gene="metG"
                     /locus_tag="STBA_RS03515"
                     /old_locus_tag="STBA_07060"
     CDS             4953..6689
                     /EC_number="6.1.1.10"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432669.1"
                     /locus_tag="STBA_RS03515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07060"
                     /product="methionine--tRNA ligase"
                     /protein_id="WP_077057827.1"
                     /transl_table=11
                     /translation="MARHLITSALPYINGIKHLGNMVGSMLPADVYARYLRQRGHDVLY
                     ICATDEHGTPAELAAKAAGLPVAEFCARQHEAQKAVYDGFGLRFDHFGRTSSPQNIEIT
                     QHFARKLQENGFIEERATRQVYSPADGRFLPDRYIVGTCPYCGYEAARGDQCENCTRVL
                     DPTDLLDARSAVSGSTDLEVRETKHLFLLQSKLEREVESFVDTAGKEWPTLASSIARKW
                     LTEGLLDRAITRDLEWGVPVPADVWPELAAEGKVFYVWFDAPIGYIGATKEWADAAGEG
                     EERDWRAWWYEADEAVRYTEFMAKDNVPFHTVMFPATQLGTREPWKKVDVVKAFNWLTY
                     YGGKFSTSQRRGIFADAALELLPADYWRYFLMAGAPESDDASFSWELFASVVNKDLADT
                     LGNFVNRVLTFSRKRFGDGVPAGHPAGEAERRLGEEVARLLAEYEEHLSALQFRKATAQ
                     LRALWSAGNAYLEEKAPWQQIKTDQDAAALTLRTAMNLIHLYAVVSEPVIPFTCGTLRS
                     VFATAAEGGAGGEARWVTPEAARSLDTVPAGTDFTVPPVLFTKITDDDLDAYRERFGGQ
                     DG"
     gene            complement(6823..8178)
                     /locus_tag="STBA_RS03520"
                     /old_locus_tag="STBA_07070"
     CDS             complement(6823..8178)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983072.1"
                     /locus_tag="STBA_RS03520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07070"
                     /product="ATP-binding protein"
                     /protein_id="WP_077057828.1"
                     /transl_table=11
                     /translation="MPEQPRHGGGAPLHSRLAFGAPCGGELGTRRRLLRLATFPAVLVA
                     VIATAAVVYLLVGGRPGAPHGDCPLWAVLASAVLLTGAVVVGAAVVAAGEARSHTARLA
                     GLRRQAARGRVELQALLVKVERGERIRPPEGPAPAEPAEDQLDQLRHEIEAAQHAAESA
                     VFQASSLVSGGGDERVEVFVSLARRLQSFVHRQIEYLEELEEDVEDPELLKGLFHVDHL
                     ATRVRRHAENLAVLGGAVPRRQWSRPVDMSEVLRSCIAEVEHYARVKLVPPVEGSVRGH
                     AVADVIHLLAELVENATEFSAPQTQVLLRVQRVTAGIAIEVEDRGLGMTPAEQVRMNAL
                     LAGAERMDVAELLEDGRVGLFVVATLARRHDIVVQLQSNIYGGVQAVLVLPSELLGDGP
                     GAGQGAGRAIGALRAAPLDSLSRAPLPRRPSLVPGVMAASPQGAGLAEEADD"
     misc_feature    complement(8309..8321)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(8348..9013)
                     /locus_tag="STBA_RS03525"
                     /old_locus_tag="STBA_07080"
     CDS             complement(8348..9013)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327113.1"
                     /locus_tag="STBA_RS03525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07080"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_077057829.1"
                     /transl_table=11
                     /translation="MNDELFPRERVEVMPGAVHLPGWLRDGRPAELLAACRAWALPPAG
                     LRTVRTPGGGEMSVRQLSLGWHWYPYGYARTVVDGDGAPVKPFPAWLGDWARQAAADAG
                     PSVTDAGGPSGIPFDIALVNFYDAGARMGMHRDSDERSPAPVVSFSLGDTCVFRFGTPQ
                     SRGRPWQDVELRSGDAFVFGGPSRLAYHGVPRTRPGSGPAGLGLRGRLNVTVRAAGLD"
     gene            9143..9949
                     /locus_tag="STBA_RS03530"
                     /old_locus_tag="STBA_07090"
     CDS             9143..9949
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018853725.1"
                     /locus_tag="STBA_RS03530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07090"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_077057830.1"
                     /transl_table=11
                     /translation="MTGQQTGDSALVGIRNFRDVGGLPAAGGARVRHGVLYRSGHLAHA
                     TEADRAFLSGLGLRTVFDFRNATDQALEGLDVELPGVRNVNLPLNDPADGAEFWALVRD
                     GSLERLRAELTEERTVRRMIESYREMVLHRNAEHGEVLRTLSGGGLPALVHCSAGKDRA
                     GLTVAVTLLAVGVARETILADYLESNAPHRRYRVRRGPETEGGGAELHPEVARLLAPLF
                     DARAEYILAAFDQIDATWGGTERYLSEGLGVTAAEREGLRAALLTG"
     gene            complement(10001..11059)
                     /locus_tag="STBA_RS03535"
                     /old_locus_tag="STBA_07100"
     CDS             complement(10001..11059)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004951789.1"
                     /locus_tag="STBA_RS03535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07100"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_077057831.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.7e-57, bitscore:
                     191.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPAHPDGGVPALLERGRALAAPALRATVGRLAPPMNTVAAYHF
                     GWIDAEGRPAASDSGKAIRPALALLSAEAAGAAPETGVPGAVAVELVHNFSLLHDDLMD
                     GDEQRRHRDTVWKVHGPAQAILVGDALFALANEVILAADTAHAARAARRLAAASRRLVD
                     GQAQDIAFEHRERVTVAECLEMEGNKTGALLACAASIGAVLGGADDALADSLELYGQHL
                     GLAFQAVDDLLGVWGDPRSTGKLTWSDLRQRKKSLPVVAALAARGPAAERLTALLTADA
                     KKTQEEFDDFDEAEFAVRADLIEEAGGRAWTEAEARRQYDTAVAALHRVDMPEQVRNRL
                     TALADFVVVRQK"
     gene            complement(11069..12478)
                     /gene="hpnE"
                     /locus_tag="STBA_RS03540"
                     /old_locus_tag="STBA_07110"
     CDS             complement(11069..12478)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546810.1"
                     /locus_tag="STBA_RS03540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07110"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_077057832.1"
                     /sec_met_domain="DAO (E-value: 1.5e-09, bitscore: 36.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPRRPGHTVVVGGGLAGVTTALALADRGQSVTLVESRPRLGGL
                     AFSFRRDSAAGTLTVDNGQHVYLRCCTAYRGFLQRIDAAALAPLQRRLDVPVLDGATGR
                     MGRIRRTGLPVPLHLAASLARYPHLTPGERAAAARATLALRALDPADPALDGQDFASWL
                     RARGQTDRAIAALWDLIGVATLNARAADVSLALAAMVFRTGLLTEPGAADIGIPRVPLG
                     ELHDTRARAALDRSGVTTLLATRARRLRPAPGGGWHVTVTAPREEPRTGRELAADAVVL
                     AVPHDAAHRLLPAGALADPGRLRRIGSAPILNVHVIYDRPVLRRPFLAALHSPVQWIFD
                     RGGPAGLGVPDGRRGQYLALSQSAAGEEIQLPTDVLRKRYLPELARLLPRAAGAGVRDF
                     FVTREREATFAPAPGVGQLRPGPQTRVAGLYLAGAWTATGWPATMEGAVRSGHAAARAV
                     LGRARTSHGHD"
     gene            complement(12475..13404)
                     /gene="hpnD"
                     /locus_tag="STBA_RS03545"
                     /old_locus_tag="STBA_07120"
     CDS             complement(12475..13404)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542865.1"
                     /locus_tag="STBA_RS03545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07120"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_077063081.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.9e-60, bitscore:
                     201.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.9e-67,
                     bitscore: 226.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSSPLPPPVVAAYHYCHSVAEQHARNFSYGARLVPAPKRRALT
                     AVYAFARRVDDIGDGRLDPAAKEERLSATRALLERVRDGAVQQDDTDPVAVALGDAARR
                     YPIPLGALDELIDGVLMDVRGHTYETWDDLRVYCTRVAGTIGRLSLGVFGVLPGAREAE
                     RAPEYADTLGLALQVTNILRDIREDAANGRVYLPAEDLRKFGCPEGPGLAGPGPESDFT
                     GLIRFQVRRARELFAEGSRLLPMLDRRSGACVTTMAGIYHRLLDRIEADPRAVLRHRVT
                     LPAGHKILVAARGLTGLDARRAARRERL"
     gene            complement(13416..14315)
                     /gene="hpnC"
                     /locus_tag="STBA_RS03550"
                     /old_locus_tag="STBA_07130"
     CDS             complement(13416..14315)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513262.1"
                     /locus_tag="STBA_RS03550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07130"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_077063082.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.2e-40,
                     bitscore: 138.4, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 5.6e-37, bitscore:
                     126.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATAEGDATLAKAAHENFPVAPRFLPRAWRGDLMAVYGFARLVD
                     DIGDGDLPPGGADAARLGLAPGRADDRLLMLDALEADLRRVFASAHGGAPPRHPLLREL
                     IPTVRRAALTPDPFLALIEANRVDQRVRRYATHADLLGYCELSANPVGRLVLGITGTST
                     PERIRRSDAVCTALQLIEHLQDVAEDLARDRIYLPAEAMHRFHVTEADLAAPTANASVR
                     TLVAHMSDRARRLLDEGAPMMTGVSGRLRLLLAGFVGGGRAAAQAIADAGYDVLAGPPR
                     ASKGGLLYAAATTLRRGT"
     misc_feature    14364..14378
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.0"
                     /tool="antismash"
     gene            complement(14417..15211)
                     /locus_tag="STBA_RS03555"
                     /old_locus_tag="STBA_07140"
     CDS             complement(14417..15211)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981490.1"
                     /locus_tag="STBA_RS03555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07140"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_077057833.1"
                     /transl_table=11
                     /translation="MAEQDIPAGGADEARIPTVIADDLHIVYRVHGGGGRGTATAALRR
                     MVRRERGYKMREVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPPERGRVYT
                     DGQPSLLGVNAALMNDLTGERNVILGGLAMGMTRDEIKHRYQDIVDFSGINDKGDFISL
                     PMRTYSSGMQARLRFSIAVAKEHDVLMIDEALATGDKKFQRRSEAKVRELRAEAGTVFL
                     VSHNNKSIRDTCDRVLWLEKGELIMDGPTDQVLKAYEEETGK"
     gene            complement(15204..16133)
                     /locus_tag="STBA_RS03560"
                     /old_locus_tag="STBA_07150"
     CDS             complement(15204..16133)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432679.1"
                     /locus_tag="STBA_RS03560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07150"
                     /product="ABC transporter permease"
                     /protein_id="WP_077057834.1"
                     /transl_table=11
                     /translation="MSETTHDSAPPRDVPLAELAARHGLSVSGARPSLPGYVRQLWGRR
                     QFIVAFSQAKLAAQYSQAKLGQIWQVLTPLLNAFVYFLIFGLLLGGRGGMENDEYIPFL
                     VIGVFVFTFTQNSVMSGVKSISGNLGLVRALHFPRASLPISLSLQQLQQLLFSMVIVLV
                     IALGFGHYPSWLWLLVLPALALQLVFNTGLALFFARLGSATPDLAQLMPFVLRTWMYAS
                     GVIFPLRHMVEEKDDWPSWVDPSLLADILAANPAAVYMDLVRYALMDGTFAESVPMITW
                     LYALGWALVVGVGGFVYFWKAEERYGRG"
     gene            complement(16217..17062)
                     /locus_tag="STBA_RS03565"
                     /old_locus_tag="STBA_07160"
     CDS             complement(16217..17062)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568725.1"
                     /locus_tag="STBA_RS03565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07160"
                     /product="glycosyltransferase"
                     /protein_id="WP_171987856.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3e-10, bitscore:
                     38.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDRPEELRALLDSVAAQDGAAIEVVVVGNGAELPDLPPGVRTLE
                     LPQNLGIPGGRNVGIEAFGPGGSEVDVLLFLDDDGRLPDKTTAETVRSAFEADPQLGIV
                     SFRIADPENGSTQRRHVPRLRASDPMRSSRVTTFLGGANAVRTHVFQQVGGLPDNFFYA
                     HEETDLAWRALDAGWHIDYRADLVLHHPATAPSRHAVYHRMVARNRVWLARRNLPLPLV
                     PVYLLDWALLTLARRPSRAALKAWFGGFFEGWRTPCGPRRPMRWRTVWRLTRLGRPPVI
                     "
     gene            complement(17110..17895)
                     /locus_tag="STBA_RS03570"
                     /old_locus_tag="STBA_07170"
     CDS             complement(17110..17895)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962488.1"
                     /locus_tag="STBA_RS03570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07170"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_077057835.1"
                     /transl_table=11
                     /translation="MSKPSVAELRPVVHPSGVKDRRSGEHWAGRLYMREISLRWTRHLV
                     NTRISPNQLTYLMVLTGVAAGAALLVPGPAGALTGALLIQLYLLLDCVDGEVARWRGQT
                     SITGVYLDRVGHYLAEAALLVGFGLRAADVFAVEEAAPNWLWAFLGTLAALGAILIKAE
                     TDLVDVARTRGGLPAVRDDAAIPRSSGLALARRAAAALKFHRLVGGVEASLLILLVAVL
                     DLVRGDLFFTRLGVALLAAVALVQTLLHLVSVLASSRLR"
     gene            complement(17873..18934)
                     /locus_tag="STBA_RS03575"
                     /old_locus_tag="STBA_07180"
     CDS             complement(17873..18934)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308910.1"
                     /locus_tag="STBA_RS03575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07180"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_077057836.1"
                     /sec_met_domain="Fe-ADH (E-value: 2.4e-19, bitscore: 68.0,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVSVDITAGALDNLAGLLADQRISSSGRLAVAISN
                     GSGAALRERLSPALPGADWYEVAGGTIDAAVQLADAMRSGHYDAVVGLGGGKIIDAAKY
                     AAARVGLPMVAVATNLSHDGICSPVSTLDNDAGRGSYGVPTPIALVIDLDVIREAPVRY
                     VRSGIGDAVSNISAIADWELSHRETGEQIDGLAAAMARQAGEAVLRHPGGCGEDPFLTV
                     LSEALVLSGIAMSIAGHTRPSSGACHEISHALDLLHPRRSALHGEQVGLGAAFAMHLRG
                     APDQCGLIAEVLRRHGLPVLPDHIGFTADEFVAAVAFAPQTRPGRYTILEHLDLTTDQI
                     RDAYADYVKTIGS"
     gene            complement(18922..19686)
                     /locus_tag="STBA_RS03580"
                     /old_locus_tag="STBA_07190"
     CDS             complement(18922..19686)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640650.1"
                     /locus_tag="STBA_RS03580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07190"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_077057837.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.2e-10, bitscore:
                     40.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVVEADGENSRTVLDLTLA
                     NFAEVGLTEAAVVVGYRKEAVYERKETLERRHGVRLTLVENDKAEEWNNAYSLWCARDV
                     IKEGVILANGDTVHPPSVERTLLAAQAAGGRDGGRIILALDTVKKLADEEMKVVTDPEK
                     GVQRITKLMEPAEATGEYIGVTLIEPAAADALADALRTTFERDPQLYYEDGYQELVHRG
                     FHLDTAPIGDISWVEIDNHDDLARGREIACRY"
     gene            complement(19683..21524)
                     /locus_tag="STBA_RS03585"
                     /old_locus_tag="STBA_07200"
     CDS             complement(19683..21524)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="STBA_RS03585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07200"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_077063084.1"
                     /transl_table=11
                     /translation="MSTAILTGPPPPGSPVEHDLRELGFSVRVADGTAGLTRALDAVPA
                     AERVAVVDPRFVGHRHSLRLGLTDPRFDAAAVPGAVTVLPRERGALAGALTAVTAQGAG
                     RAPEAAGRTVAAPPAAGCLADRLATGLDAAGTRVHRPELGTLVAAVPASEAERARAEAA
                     VAAVDEEAVRLRSAVKSRDGFFTTHCISPYSRYLARWCARRGLTPNQVTTASLITALVA
                     AGCAATGTRGGFVAAGLLLLASFVLDCADGQLARYSLQYSTLGAWLDATFDRAKEYAYY
                     AGLALGAARGGDDVWALALGAMILQTCRHIVDFAFNEAHPPAPGGTSGGATALSGRLDR
                     IGWTVWVRRMIVLPIGERWALIAVLTALTTPRVTFTVLLIAGGLAGCYTTAGRLLRSRR
                     LPGGAPGTAAALTGLADSGPLAEGIARLRPRAAGSSRTAPLWALTGTALLLGLLLLPGV
                     AGSWTALAAAGLYALCAGRAVAAEPVRPFDWLLPPLFRCGEYLTFLVLAADSGVNGALP
                     AAFFVVAACAYHHYDTVYRLRGGAGAPPRRLVLATGGHEGRVLVACAAAALWADGQGFT
                     TALAVLGGATALLVLGESIRFWVSSQAPAVHDEGEPA"
     misc_feature    complement(21609..21624)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     gene            21731..22711
                     /gene="galE"
                     /locus_tag="STBA_RS03590"
                     /old_locus_tag="STBA_07210"
     CDS             21731..22711
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-207). E-value:
                     6.4e-13. Score: 40.3. Matches aSDomain:
                     nrpspksdomains_STBA_RS03590_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432685.1"
                     /locus_tag="STBA_RS03590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07210"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_077057838.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.5e-16, bitscore:
                     57.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.9e-11,
                     bitscore: 40.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 7.5e-11, bitscore:
                     40.3, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWLITGGAGYIGAHVVESMCAAGERVVVLDDLSSGSPARLPADV
                     PLVRGSVLDRELLDATLAGHGVTGVVHLAARKQVAESVAEPTGYWRANVHGLTVLLEAV
                     AAAGLRTFVFSSSAAVYGMPGGGLVTEETPCHPLSPYGETKLAGEWLVRAAGRAHGIAT
                     ACLRYFNVAGAARPELADTGAANVIPMFFERLARGQAPEIFGDDYPTPDGSCVRDYVHV
                     ADLAEAHLAAARHLSGRPAAGGEDLTVNIGTGRGASVKELAALVGQVTGHGGPPRISGR
                     RPGDPARVVASVDLAAERLGFTAGRGLEEMVSSAWAGWCHLHPQM"
     CDS_motif       21734..21820
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS03590_0001"
                     /evalue="1.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="STBA_RS03590"
                     /protein_end="30"
                     /protein_start="1"
                     /score="17.5"
                     /tool="antismash"
                     /translation="SWLITGGAGYIGAHVVESMCAAGERVVVL"
     aSDomain        21929..22351
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STBA_RS03590_NAD_binding_4.1"
                     /evalue="6.40E-13"
                     /label="STBA_RS03590_NAD_binding_4.1"
                     /locus_tag="STBA_RS03590"
                     /protein_end="207"
                     /protein_start="66"
                     /score="40.3"
                     /tool="antismash"
                     /translation="VTGVVHLAARKQVAESVAEPTGYWRANVHGLTVLLEAVAAAGLRT
                     FVFSSSAAVYGMPGGGLVTEETPCHPLSPYGETKLAGEWLVRAAGRAHGIATACLRYFN
                     VAGAARPELADTGAANVIPMFFERLARGQAPEIFGDD"
     CDS_motif       22175..22294
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STBA_RS03590_0002"
                     /evalue="5.20E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="STBA_RS03590"
                     /protein_end="188"
                     /protein_start="148"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="EWLVRAAGRAHGIATACLRYFNVAGAARPELADTGAANVI"
     misc_feature    complement(22780..22794)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            22864..23802
                     /locus_tag="STBA_RS03595"
                     /old_locus_tag="STBA_07220"
     CDS             22864..23802
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="STBA_RS03595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STBA_07220"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_077057839.1"
                     /transl_table=11
                     /translation="MGAGHHHGGAPPAGPGTAGAAYRGRLRVALAIACVLLVAELAGAA
                     ATGSLALLADAGHVATDAVGIGMALLAIHVANRPAGSDRRTFGFARAEILAALANCVLL
                     LGVGGYILVEAIGRLRDPAEVPGGLTVVFGVVGLLLNCASLALLMRGQRESLNVRGAFL
                     EVAADALGSLAVVAAALVIVFTGWQQADPVASLLIALLIVPRTVKLAREALDVLLESAP
                     KDVRVAEVRAHILELPGVEDLHDLHVWTITSGMPALSAHVVVARETLDAVGHERLLHDL
                     QGCLGEHFDVAHCTFQLEPSGHAAHEVGLCH"
ORIGIN
        1 ggagcccgcc gacccggccc ccgcctactc cgcgccggtc ggcggcggca ccggcaccgc
       61 ctaccacgcc tcgggcggct cctggtcgct cggctaccac accggggtgg acttccccgt
      121 tgccacgggc acgtccgtga agtcggtgac ggccggcgag gtggtctcgg cgggctggtc
      181 cggctcgttc ggctacgagg tcattgtccg gcatccggac gggcacttca gccagtacgc
      241 gcacctctcc gcgatctccg tctccgaggg gcagccggtc ggcaacggcc agcaggtggg
      301 gcggtccggc tcgacgggca actccagcgg accgcatctg cacttcgaaa tcaggacagg
      361 ggagtcgttc ggcacggaca tcgatccgct cgcctatctg cgggggaacg gcgtctccct
      421 ctgagcgtgg gcgcattccg gccatgcggt ggcttgatgc cgccgcatga cgggcgctca
      481 atacgggaca gatggacagg taaccgcccc gcagaaggat gttgctcctc cgtttccttc
      541 cccgatctgc cgcagggtca gtagtctcga ccgcctgggt tcaattcgtg catatgcagg
      601 ggacattgga gacgccgatg gaacgatccg cctgggctca gcccggcatc gatccatccg
      661 tgcccagcct gtcccggatg tatgacttct acctgggcgg ttcccacaac ttcgaggcgg
      721 accgcgcggc cgccagggag gccatcgcgg cgttccccgg cctgcccgcg ctggccctgg
      781 ccaaccgcgc cttcctgcgg cgggccgtgc gctacgcggt ggcggagggc gtctcccagt
      841 tcgtcgacat cgggtcgggc atcctgacct tcggcaatgt gcacgagatc gcccggcgga
      901 ccggtgacga cacccgcgtc gtctacgtcg acaacgaccc cgtcaccgtc gcccacagcc
      961 gtgccgtcct cgcgggcgac gaccgcacgg acatcctcgc cgccgacctg cgcggcccgt
     1021 ccgcgatcct gaacagcgag caggtcggcc ggctgatcga cctcggccgg ccggtggccc
     1081 tgctgctcgt ggccgtcatg cacttcctcg gcgaggacga caagccccac gagcggatcg
     1141 ccgaactgcg cgacatgctc gcgccgggca gtctgctcgc cctcacccac gcctcccccg
     1201 aacaccgccc cacggcctcg gtgccggacg cgcggatctc ggaggtctac cgcagggcgg
     1261 gcgcaacgct ggtgctgcgc tccggcgcgg agatcacgca cttcttcgag ggcttcgacc
     1321 tcgttccccc aggcgtggtc ccattgcccg actggcggcc cgacgggccg cccgacgagg
     1381 agggtcccaa ggtgaacagc ggcttcgcgg gagtaggacg caaagggtga catcctcgcc
     1441 aacggggccc accggccacc atcgcaccgg cgacagcacg gagccgtccg acggcctgcg
     1501 ccgcttcgcc gccctctggt gccgcgccgt ccacccgcgc gccgccaccc cgctctccag
     1561 acccgagttc gaggcgctgc tgctcggtct cgcgcgccgg ctcgccgacg cgctgcgcgc
     1621 cccccgtttc gaccccgcgc ccggccacgc cgtcggcgcc gccctggtcg cggcccactg
     1681 cacgtccccc gacgcgctgc ccggcatcct ggccgtcatc gactcccacc tggtggcgca
     1741 ctgcggcccg acggacgggg aggccggtcc tgacgcctcg gagagcaggg cccgctgcac
     1801 ccggctccag cacgcggtgt ccgccggttt cgcgcgtgcc ctccaggagc gcaccaggag
     1861 cgaacaggag gcgctgtcgc gcgcggccct cgccgcccag acggagatgg cggacgcgct
     1921 gcacgagagc gaggcgcgct tccgcgcggt cttcaagggg gccgcgctcg gcatcggcat
     1981 cgccgacatg gacggcacca tcctcgacgt caacgacgcc ctcaaccaga tgttcggcgg
     2041 ctcggagcag cacatccgcc accggaacgt actggactgg gcccgccccg gggaccaccc
     2101 cgaggcgggg cgcatgctcg aggagctgat gcgcggcgaa cgtgagcact accaggtcga
     2161 aaagtcctat ccccgggacg acggcacgac gctgtggacc aatctcacgg tctcgctgct
     2221 gcgcgacgcc tcaggggagc cgcgctacat gctcgcgatg accgaggacg tcagcgagcg
     2281 ccgcctgctg aatctccggc tgcgctacca ggcgacccac gacgccctga cggacctgcc
     2341 caaccgttcc ctcttcttcg agcgcctcga acaggcgctg gaccgcagcg gctcgggtcc
     2401 ggcccgcatc ggcctgtgct acctcgacct ggacgggttc aaggccgtca acgacagcct
     2461 cgggcacgcc gtcggcgacc agttgctgat cgccgtggcg gagcgcctcc agggctgcgc
     2521 ctcgggaccc ggccagatgc tggcccggat cggcggcgac gagttcgtcg cgctggtggc
     2581 cgacccgccc gagccgcggg ccgtcaccga gctcgccgag cgggcgctcg aagccctggc
     2641 cacgcccgtg gaggtcggcg gcagggaact gctggtccgg gccagcatcg gcgtcgtcga
     2701 gggggccacc cggcacctga cgtcggccga ggtgctgcgc agcgccgaca tcacgatgta
     2761 ccgggccaag gccgagggcg gcaaccgcta cgcgctggcc gaccccgact ccgacgccag
     2821 ggcgatcagc cgccaccacc tcacgcacca cctgccggcc gcgctgaagg gctgcgagtt
     2881 cttcatcgag taccagccgc tggtcaagat ggaggacggc agcatcgagg gtgcagaggc
     2941 gctggtgcgc tggagccacc cccggcacgg cgtgctcggc cccgaccggt tcatcccgct
     3001 cgccgagcac accgggctga tcgttccgct cggccgctgg gtccttgagg aggcggtgcg
     3061 gcaggcgtgc cagtggcagg tccgcgggat aggcggggcc aggccgctga agatcaacgt
     3121 gaacctctcg ccgcgccagc tgcaccaccc ggagctggtc gcggacacca tcgccgtgct
     3181 ggaggaggcc gggctcgaac ccagctcgct gtgtctcgaa gtcaccgaga ccgccatgat
     3241 caaggccgac gagaacgagc tgcggcccct gcgcgagctg gccgagtacg gagtcggcat
     3301 cgcgctggac gacttcggca ccggctactc caacctggcc aacctgcgcc gtctgcccgc
     3361 cgacacgctc aagctggacc gttccttcac gcagggcctc cagcgcgacc cggcggaccc
     3421 ggtcgacctg aagatcgtcg agggcatcgt ctcgctggcc cacaccctcc aactgtccgt
     3481 caccgtggag ggcgtggaga catccgccca ggccgagcag ctgcgcgagc tgggctgcga
     3541 ctccgcccag ggctggttct acgcacgccc cggccctccg gagcgcctgc ccgaggcggt
     3601 ctgagcgggc ggccgcccgc ctcaggtcac gatccgcagc cgccgcggcg gcgccgtgcg
     3661 cggcgcgggc agccgcagcg gcgcggcgcc cggggtcagc gagccgagga ccgcggggcc
     3721 accggcgccg gtggccgagg gcacggagcc cgcgaggccg tgcacggtga ggaagccgag
     3781 cagggcgaac aggtacgcct ccttcgcctg cgccggcagg ccgaagcgct ccggcggaac
     3841 gagcgcggcc ggtgcggcga gcgcgcgcag ccggtccatc agcaccgggt tccgcacgcc
     3901 gccgcccgag acgaccagct ccgtcagcgc gtgctcgcgg caggccgccg cgaccaggcg
     3961 cgcggtcagc tcggtgagcg tggcgaccag gtcgtccgtg gccgggcgcc ggcccacggc
     4021 gcgcagccgc gttcccaggt aatccgcgtg gaacagctcc ttgccggtcg acttcggcgg
     4081 cggcagccgg tagtacggct cgtccagcag cgcgtcgagc agcccggcgt ccacggtgcc
     4141 gcgggccgcg cgggcgcccc cggtgtccat gcactccgct cccccgctcg cctcggtgac
     4201 ggccgcgtcg atcagcgcgt tggccgggcc gaggtcgtag gcgaggacac cgccgtcggc
     4261 gccgcgggcg gtgatgttgg cgattccgcc gaggttgagc gccccgcgcg cgggcgcgcc
     4321 cggcgcctcg tcgaggatca gcagcgcgtc gagcagcgcg gccagcggcg cgccctgccc
     4381 gccgcgtgcg atgtcgcggg tgcgcaggtc ggagaccacg ggcaggccgg tggcctcggc
     4441 gatccaggcg gcggcgccga gctggagggt gccgcgggcg cgggcgtccg ccacccagtg
     4501 gtagaccgtc tgtccgtgcg agaccacgag gtccgcgcgc ccgccggcga gggccgcgtc
     4561 ggcgcgcgcc gcgacctcgc cgaagaactg cccgagtccg gtgtcgagcc ggcagacccg
     4621 ttccagggtg gtggcggcgg gcggcaggca gccggccagc tcgccgcgca gcgcggccgg
     4681 atacggctcg gtgtgcaggc cacgggggcg caggcacagg tcggtgccct cgaaggccag
     4741 ctcggcgacg gcggcgtcca ccgcgtcgta cgaggtgccg ctgagcatgc cgatcaccag
     4801 ccacggccgg tcgccggaaa acctggtggg gacgcccgcc accggctcgg taggatgagt
     4861 gaagcccata aacgtgatcc gtcacactcc gtggcccaat tcacggcccg acagggctca
     4921 ttgactctac tcacccattg gagcatccga ggatggcccg acacctcatc accagtgcgc
     4981 tgccctacat caacgggatc aagcacctgg ggaacatggt gggctcgatg ctccccgccg
     5041 acgtatacgc ccgctatctg cggcagcgcg gccacgacgt gctgtacatc tgcgcgaccg
     5101 acgagcacgg caccccggcc gagctggccg ccaaggcggc cgggctgccg gtcgccgagt
     5161 tctgcgcgcg gcagcacgag gcgcagaagg cggtgtacga cggcttcggg ctccgcttcg
     5221 accacttcgg caggacgtcg tccccgcaga acatcgagat cacccagcac ttcgcccgca
     5281 aactccagga gaacgggttc atcgaggagc gcgcgacgcg gcaggtgtac tcgcccgccg
     5341 acggccgttt cctgcccgac cgttacatcg tgggcacctg cccctactgc gggtacgagg
     5401 cggcgcgcgg cgaccagtgc gaaaactgca cccgggtgct cgacccgacg gatctgctcg
     5461 acgcgcgctc cgcggtcagc gggagcacgg atctggaggt gcgggagacc aagcacctgt
     5521 tcctgctcca gtcgaagctg gagcgggagg tggagtcctt cgtcgacacc gcgggcaagg
     5581 agtggccgac gctggcctcc tccatcgcgc gcaagtggct gaccgagggg ctgctcgacc
     5641 gggcgatcac ccgggacctg gagtggggcg tgccggtccc cgccgacgtc tggcccgagc
     5701 tggcggccga gggcaaggtc ttctacgtct ggttcgacgc cccgatcggc tacatcggcg
     5761 ccaccaagga gtgggcggac gcggcgggcg agggcgagga gcgcgactgg cgcgcgtggt
     5821 ggtacgaggc cgacgaggcg gtgcggtaca ccgagttcat ggccaaggac aacgtgccgt
     5881 tccacacggt gatgttcccg gccacgcaac tgggcacgcg cgagccctgg aagaaggtcg
     5941 acgtcgtcaa ggcgttcaac tggctgacgt actacggcgg caagttctcc acctcgcagc
     6001 gccgcgggat cttcgccgac gccgcgctgg agctgctgcc cgcggactac tggcggtact
     6061 tcctgatggc gggcgcaccc gagtcggacg acgcgtcctt ctcctgggag ctgttcgcct
     6121 ccgtggtgaa caaggatctc gccgacaccc tgggcaattt cgtcaaccgg gtgctcacct
     6181 tctcgcggaa gcgcttcggc gacggggtcc cggccgggca tccggcgggc gaggcggagc
     6241 ggcggctcgg tgaggaggtc gcgcggctcc tcgcggagta cgaggagcac ctgtcggcgc
     6301 tccagttccg caaggcgacg gctcagctgc gcgcgctgtg gagcgcgggg aacgcctacc
     6361 tggaggagaa ggcgccctgg cagcagatca agaccgatca ggacgccgcg gcgctgacgc
     6421 tgcgcaccgc gatgaatctg attcatctct acgcggtggt ctccgagccg gtcattccgt
     6481 tcacctgcgg gacgctgcgc tcggtgttcg cgacggccgc ggagggcggc gcgggcggcg
     6541 aggcccgctg ggtgacgccc gaggccgcgc ggtcgctgga cacggtgccg gccgggacgg
     6601 acttcaccgt gccgcccgtg ctgttcacga agatcaccga cgatgacctc gacgcgtacc
     6661 gggagcgctt cggcggccag gacggctgag gaccgaggcc ggctgagggc ggccggagtc
     6721 gccgtcctca cgccgtcccc gccggccggg ccgactgctc cgcccgtccg cgcggtcctg
     6781 gccgcggcgc ctccctccca cggggcgcga gcggatgtga cgtcagtcgt cggcctcctc
     6841 ggcgagcccc gcgccctgcg gggacgccgc catgaccccg ggcaccagcg acggccggcg
     6901 cggcagcggg gcgcgcgaca ggctgtccag cggcgcggcc ctgagcgccc cgatggcgcg
     6961 ccccgcaccc tgcccggcgc cgggaccgtc gccgagcagc tcggacggca gcacgagcac
     7021 ggcctgcacg ccgccgtaga tgttgctctg gagctgtacg acgatgtcgt gccgcctggc
     7081 gagggtggcg accacgaaca ggcccacccg gccgtcctcc agcagctcgg ccacgtccat
     7141 ccgctccgcg ccggcgagga gggcgttcat ccggacctgc tccgccgggg tcatgcccag
     7201 gccccggtcc tccacctcga tcgcgatgcc cgccgtgacg cgctgcacgc gtagcagcac
     7261 ctgcgtctgc ggggcggaga actcggtcgc gttctcgacg agctcggcga gaaggtggat
     7321 gacgtcggcg acggcgtgcc cccgcacgct gccctcgacg ggcggcacca gcttgacccg
     7381 cgcgtagtgc tcgacctccg cgatgcagga ccgcagcacc tcggacatgt cgaccgggcg
     7441 gctccactgg cggcgcggca ccgcgccgcc gagcaccgcg aggttctccg cgtgccgtct
     7501 gacgcgggtg gccaggtggt cgacgtggaa cagccccttc agcagctccg ggtcctcgac
     7561 gtcctcctcc agctcctcca ggtactcgat ctgccggtgc acgaaggact ggaggcggcg
     7621 ggcgaggctg acgaacacct cgacccgctc gtcaccgccg ccgctgacga gggaggacgc
     7681 ctggaagacc gcggactccg cggcgtgctg ggcggcctcg atctcgtgcc gcagctggtc
     7741 gagctggtcc tcggcgggct cggcgggcgc cgggccctcg ggcggcctga tgcgctcgcc
     7801 ccgctcgacc ttgaccagca gcgcctggag ctccacgcgc ccgcgggccg cctggcggcg
     7861 cagcccggcg aggcgggccg tgtgcgacct ggcctcgccc gcggcgacga cggcggcccc
     7921 gacgaccacc gcaccggtca gcagcacggc cgaggcgagc acggcccaca ggggacagtc
     7981 gccgtggggg gccccgggcc ggccgccgac cagcagatac acgacggccg cggttgcgat
     8041 cacggcgacc agcacggcgg ggaacgtggc caggcgcagg aggcggcgtc tggtcccgag
     8101 ctctccgccg cacggcgcgc cgaaggccag ccggctgtgc aggggcgcgc ctcccccgtg
     8161 gcgtggctgt tctggcatcg gtgtccttat caggcaggtc aagtgggcgt aaggccacgc
     8221 tatgcgtcaa caggtaggcg aacgggcaca gttccggcat tcgccacccc tcgccacctt
     8281 ccaacgagtg aaaacagccg gcccggccgt gacggcggca cccgtcggcg gccccctccg
     8341 gaggaactca gtcgagcccg gcggcgcgga ccgtgacgtt cagcctgccc ctcagtccga
     8401 gccccgccgg gccgctgccg gggcgggtgc ggggcactcc gtggtaggcg aggcgcgagg
     8461 gcccgccgaa gacgaacgcg tcgccgctgc gcagctcgac gtcctgccac ggacgcccgc
     8521 ggctctgcgg ggtgccgaag cggaagacgc acgtgtcgcc gaggctgaag gagaccacgg
     8581 gcgcgggcga gcgttcgtcg ctgtcgcggt gcatgcccat ccgggcgccg gcgtcgtaga
     8641 agttgaccag ggcgatgtcg aacgggatgc cggacggtcc gcccgcgtcg gtgaccgaag
     8701 gaccggcgtc ggcggcggcc tgccgcgccc agtcgccgag ccaggcgggg aacggcttga
     8761 ccggcgcacc gtcgccgtcg acgacggtgc gggcgtaacc gtaggggtac cagtgccatc
     8821 ccaggctgag ctgccggacg gacatctccc cgccgcccgg cgtccgtacc gtgcgcagcc
     8881 cggccggggg cagcgcccac gcgcggcagg cggccagcag ctcggccggt cgcccgtccc
     8941 gcagccagcc cggcaggtgc acggcgcccg gcatcacctc gacccgctcg cgcgggaaca
     9001 gctcgtcgtt catctcccca tcctcacccg ggagaagaag ggccgggccg ccggccgggg
     9061 catgccgtag ggtcggcccg ggaaccggcc cctgcggtgg cagcggcggg gcgccggcgg
     9121 cagccgacgg agggagacgc acgtgacggg gcagcagacg ggtgattcgg cgctcgtggg
     9181 gatacggaac ttccgcgatg tgggcggcct gccggcggcg ggcggggcgc gggtgcggca
     9241 cggggtgctc taccgcagcg ggcatctggc ccacgcgacc gaggccgacc gggcgttcct
     9301 ttccggtctg gggctgcgca ccgtcttcga cttcaggaac gcgaccgacc aggcgctgga
     9361 gggcctggac gtcgagctgc ccggggtgcg caatgtgaac ctgccgctga acgacccggc
     9421 cgacggcgcc gagttctggg cgctggtgcg cgacgggagc ctcgagcggc tgcgggccga
     9481 gctgaccgag gagcggacgg tgcggcggat gatcgagagc taccgcgaga tggtgctgca
     9541 ccgcaatgcg gagcacggcg aggtgctgcg gaccctgtcc ggcggcggcc tgcccgcgct
     9601 ggtgcactgt tcggcgggga aggaccgggc ggggctgacg gtggccgtga cgctcctcgc
     9661 ggtcggcgtg gcgcgggaga cgatcctggc ggactacctg gagtccaacg cgccgcaccg
     9721 gcggtaccgc gtgcggcgcg gtcccgagac ggagggcggc ggtgcggagc tgcacccgga
     9781 ggtggcccgt ctgctggccc ctctcttcga cgccagggcg gagtacatcc tggccgcgtt
     9841 cgaccagatc gacgcgacgt ggggcggcac cgagcggtac ctgagcgagg ggctcggcgt
     9901 gaccgcggcg gagcgcgaag ggctgcgcgc cgcgctgctg accggctgac cggctgaccg
     9961 gcggccccgc ccgggccggg cacggccggt cccggccggc tcacttctgg cggaccacga
    10021 cgaagtcggc gagcgcggtc agccggttcc tgacctgctc cggcatgtcc acgcggtgca
    10081 gggcggccac ggccgtgtcg tactggcgtc gggcctccgc ctcggtccac gcccggccgc
    10141 cggcctcctc gatcagatcg gccctgacgg cgaactcggc ctcgtcgaag tcgtcgaact
    10201 cctcctgcgt cttcttggcg tcggccgtca gcagcgcggt cagccgctcc gcggcgggcc
    10261 cgcgggccgc gagtgcggcg accacgggca gcgatttctt gcgctgtctg aggtcgctcc
    10321 acgtcagctt gcccgtggag cgcgggtccc cccagacgcc gagcaggtcg tcgacggcct
    10381 ggaaggcgag cccgaggtgc tggccgtaca gctccaggct atcggcaagg gcgtcgtccg
    10441 cgccgccgag tacggcgccg atggaggccg cgcacgcgag cagcgcgccg gtcttgttgc
    10501 cctccatctc caggcactcg gcgacggtga cgcgctcgcg gtgctcgaag gcgatgtcct
    10561 gggcctggcc gtcgacgagc cggcggcttg cggcggccag ccgccgcgcg gcgcgcgcgg
    10621 cgtgggcggt gtccgcggcg aggatcacct cgttcgccag cgcgaagagc gcgtcgccga
    10681 cgaggatcgc ctgggccggg ccgtggacct tccacacggt gtcgcggtgt cggcgctgct
    10741 cgtcgccgtc catcaggtcg tcgtggagca gggagaagtt gtgcaccagt tcgacggcga
    10801 cggcgccggg cacgcccgtt tccggcgccg cgcccgccgc ctcggccgac agcagggcca
    10861 gggcgggcct gatggccttg ccgctgtcgc tcgcggccgg gcggccctcg gcgtcgatcc
    10921 acccgaagtg gtaggcggcg acggtgttca tcggcggggc gaggcggccg acggtggcac
    10981 gcagggcggg cgcggccagc gcccggccgc gttccagcag tgccgggacg ccaccgtccg
    11041 ggtgggctgg ctggttcacg tgctctcctc agtcatgtcc gtgcgatgtc cgcgcccggc
    11101 cgaggaccgc ccgggccgcg gcgtggccgc tgcgcacggc gccctccatc gtggccggcc
    11161 acccggtggc ggtccacgcg ccggccaggt acaggccggc gacgcgggtc tgcgggccgg
    11221 ggcgcagctg cccgacgccg ggggcgggcg cgaaggtggc ctctcgttcg cgggtcacga
    11281 agaagtcgcg gaccccggcg cccgcggccc gcggcaggag ccgggccagc tccggcaggt
    11341 agcgcttgcg cagcacgtcc gtcggcagct ggatctcctc gcccgccgcc gattgcgaca
    11401 gtgccaggta ctggccgcga cggccgtccg gcacgccgag cccggcgggg ccgccgcggt
    11461 cgaagatcca ctgcacgggg ctgtgcagcg cggcgaggaa cgggcggcgc agcacgggac
    11521 ggtcgtagat cacgtggacg ttgaggatcg gtgcgctgcc gatgcgccgc agccggccgg
    11581 ggtcggccag ggcaccggcg ggcagcagcc ggtgggcggc atcgtgcgga acggccagca
    11641 cgacggcgtc cgcggccagc tcgcggccgg tgcgcggctc ctcgcgcggt gcggtcacgg
    11701 tcacgtgcca gccgccgccg ggcgcggggc gcaggcggcg ggcgcgggtg gcgagcaggg
    11761 tggtgacgcc cgaacggtcc agcgcggcac gggcgcgggt gtcgtgcagc tcgccgagcg
    11821 gcacccgcgg gatgccgatg tcggcggcgc ccggctcggt cagcaggccg gtacggaaga
    11881 ccatcgcggc cagggcgagg gacacgtcgg ccgcgcgggc gttcagagtg gcgacgccga
    11941 tcaggtccca cagggccgcg atggcacggt cggtctgccc cctggcccgc agccagctcg
    12001 cgaagtcctg cccgtcgagg gcggggtcgg cggggtcgag cgcgcgcagc gccagcgtgg
    12061 cccgcgcggc ggcggcccgc tcgcccggcg tcagatgcgg gtagcgggcg aggctggcgg
    12121 ccaggtgcag cggcacgggc aggccggtgc gccggatgcg gcccatgcgg ccggtggcgc
    12181 cgtcgaggac gggaacgtcg aggcggcgtt gcaggggggc gagcgcggcg gcgtcgatgc
    12241 gctggaggaa gccgcggtag gcggtgcagc agcgcagata cacgtgctgg ccgttgtcga
    12301 cggtgagcgt tccggcggcc gagtcgcggc ggaaggagaa cgcgaggccg ccgagccgcg
    12361 gcctggactc gaccagggtg acggactgcc cccggtcggc cagggcaagc gcggtggtga
    12421 cccccgcgag accgccgccg acgaccaccg tgtgccccgg gcggcggggg gtggtcacag
    12481 ccgctcccgc cgggcggcgc ggcgcgcgtc gaggccggtg agcccccgcg cggcgacgag
    12541 gatcttgtgg ccggcgggca gggtgacgcg gtggcgcagc acggcgcgcg ggtcggcctc
    12601 gatgcggtcg aggaggcggt ggtagatacc ggccatggtg gtgacgcagg cgccggagcg
    12661 gcggtcgagc atgggcagca gccgggagcc ctcggcgaac agctcgcggg cccggcggac
    12721 ctggaagcgg atcaggccgg tgaagtcgga ttcggggccg gggccggcca gcccgggccc
    12781 ctcggggcag ccgaacttgc gcaggtcctc ggcggggagg tagacgcggc cgttggcggc
    12841 gtcctcgcgg atgtcgcgga ggatgttggt gacctggagg gcaagaccga gggtgtcggc
    12901 gtactcgggg gcgcgctccg cctcgcgtgc gccgggcagc accccgaaga cgcccaggga
    12961 gaggcggccg atggtcccgg ccacgcgggt gcagtagacg cgcaggtcgt cccaggtctc
    13021 gtaggtgtgc ccgcggacgt ccatcagcac gccgtcgatc agctcgtcga gggcgccgag
    13081 cgggatgggg tagcggcggg cggcgtcgcc gagggcgacg gcgaccgggt cggtgtcgtc
    13141 ctgctggacg gcgccgtcac ggacgcgctc cagcagggcg cgggtcgcgg agagtcgttc
    13201 ctccttggcg gcggggtcga gccggccgtc cccgatgtcg tcgacgcgcc gggcgaaggc
    13261 gtacacggcg gtgagggccc ggcgtttcgg cgcgggcacg agccgggcac cgtagctgaa
    13321 gttcctcgcg tgctgctcgg cgacgctgtg gcagtagtgg taggcggcaa cgacgggggg
    13381 aggcaggggt gaacttgtgg tcacgggctc gaagctcacg ttcctcttcg cagtgtcgtg
    13441 gccgccgcgt acagcagtcc gcccttggat gcccgcggtg gccccgccag gacgtcgtac
    13501 ccggcgtcgg cgattgcctg ggccgccgcc ctgccgccgc cgacgaatcc ggcgagcagc
    13561 agccgcagcc gcccggacac gccggtcatc atgggcgcgc cctcgtcgag cagcctacgt
    13621 gcccggtcgc tcatatgggc caccagggtc cggacggagg cgttcgcggt gggggcggcg
    13681 aggtcggcct cggtgacgtg gaagcggtgc atggcctccg ccggcaggta gatccggtcc
    13741 ctggcgaggt cctccgcgac gtcctggagg tgctcgatca gctggagcgc ggtgcacacg
    13801 gcgtcggagc ggcggatgcg ctcgggggtg gaggtgccgg tgattcccag gacgaggcgg
    13861 ccgacggggt tggccgacag ctcgcagtag ccgaggaggt cggcgtgggt ggcgtagcgg
    13921 cggacccgct ggtccacgcg gttggcctcg atcagggcga ggaacgggtc cggggtgagg
    13981 gcggcgcgcc ggacggtggg gatgagctcg cgcagcagcg ggtggcgggg cggtgcgccg
    14041 ccgtgggcgc tcgcgaagac gcggcgcagg tcggcttcga gggcgtccag catcaggagc
    14101 cggtcgtcgg cccggccggg ggcgagtccg aggcgggccg cgtcggcgcc gcccggcggg
    14161 aggtcgccgt cgccgatgtc gtcgacgagg cgggcgaatc cgtagacggc catgaggtcg
    14221 ccgcgccacg cgcgcggcag gaagcggggg gccacgggga agttctcgtg ggcagccttc
    14281 gcgagggtcg cgtccccctc cgcggtggcg gtcagcacgg gcggcccgtc atcaccattg
    14341 ccgtcatact tactcttcta ccttatggtc ggacaatggc ccgccccgga cacgcgtggc
    14401 gggacgggca gcgcccttac ttgccggtct cctcctcgta cgccttcagc acctgatcgg
    14461 tggggccgtc catgatcagc tcgcccttct ccagccacag gacgcggtca caggtgtccc
    14521 tgatcgactt gttgttgtgg ctgaccagga acaccgtgcc ggcctcggcg cgcagctcgc
    14581 gcaccttggc ctccgagcgg cgctggaact tcttgtcgcc ggtggccagg gcctcgtcga
    14641 tcatgagcac gtcgtgctcc ttggcgacgg cgatggagaa ccgcagcctg gcctgcatgc
    14701 cggaggagta ggtccgcatc ggcaggctga tgaagtcgcc cttgtcgttg atcccggaga
    14761 agtcgacgat gtcctggtag cggtgcttta tctcgtcccg cgtcatgccc atggcgaggc
    14821 cgccgaggat gacgttgcgc tcgccggtga gatcgttcat cagggctgcg ttgacaccga
    14881 gcagcgaggg ctggccgtcg gtgtagaccc ggccgcgctc gggcggcagc agaccggcaa
    14941 tggcccgcag cagggtcgac ttgcccgagc cgttgctgcc gatgaggccg atggcctcgc
    15001 cgcggtaggc gacgaagctg acgccgcgca cggcgtgcac ctcgcgcatc ttgtagccgc
    15061 gctcgcggcg gaccatgcgg cgcagcgcgg ccgtggcggt gccccggcca ccgccgccgt
    15121 gcacgcggta gacgatgtgc agatcatctg cgatgacggt ggggatacgt gcctcgtccg
    15181 ccccgccggc ggggatgtcc tgttcagcca cggccgtacc gctcctccgc cttccagaag
    15241 tacacgaacc cgccgacccc cacgacgagc gcccagccga gcgcgtacag ccaggtgatc
    15301 atcgggacgc tctcggcgaa cgtcccgtcc atgagtgcgt aacgcaccag gtccatgtac
    15361 acggcggccg gattggccgc caggatatcc gccagcaggc tcgggtccac ccagctcggc
    15421 cagtcgtcct tctcctccac catgtggcgc agcgggaaga tgacgccgga ggcgtacatc
    15481 catgtccgca ggacgaacgg catcagctgg gccaggtcgg gtgtggcgct gccgagccgg
    15541 gcgaagaaca gcgcgagccc ggtgttgaac acgagttgca gagcgagcgc cgggagtacc
    15601 aggagccaca gccaggacgg gtagtgcccg aacccgagcg cgatgacgag cacgatcacc
    15661 atcgagaaca gcagttgctg aagctgctgg agggaaagcg agatgggcag cgaggcgcgc
    15721 gggaagtgca gggcccggac caggccgagg ttgcccgaga tcgacttcac gccggacatc
    15781 acggagttct gcgtgaaggt gaagacgaac accccgatca ccaggaacgg gatgtactcg
    15841 tcgttctcca taccgccgcg tccgccgagc agcaggccga agatcaggaa gtacacgaac
    15901 gcgttcagca gcggggtgag cacctgccag atctggccga gcttcgcctg gctgtactgg
    15961 gcggccaatt tcgcctggga gaaggcgact atgaattgcc ggcgccccca cagctgccgg
    16021 acgtagcccg gcagggaggg ccgggcacca ctgacggaca ggccgtgacg ggccgcaagc
    16081 tcggccaggg gcacgtcgcg ggggggcgca ctgtcgtgcg tggtctcact cactcgaact
    16141 ctcgtcctcg cagggcacaa gctggaagaa gaagccgcgc ggcggcggct actggatggt
    16201 ctcagacccg agcttgtcag atgacaggag gtcgtccgag tcgggtcagg cgccataccg
    16261 tacgccaacg catcggcctg cggggaccac acggcgtccg ccagccctcg aagaagccac
    16321 cgaaccacgc cttcagggca gcgcgcgagg gccgccgggc cagggtcagc agcgcccagt
    16381 ccaggaggta gaccgggacc agcggcagcg gcaggttgcg ccgggccagc cagacccggt
    16441 tccgcgcgac catgcggtgg tagacggcgt gcctggaggg cgcagtggcc ggatggtgca
    16501 gcaccagatc cgcgcggtag tcgatgtgcc agcccgcgtc cagcgcccgc caggccaggt
    16561 cggtctcctc gtgggcgtag aagaaattgt ccggcaggcc gccgacctgc tggaagacgt
    16621 gggtgcgcac ggcgttggcg ccgccgagga aggtggtgac ccgggaggag cgcatcgggt
    16681 cggaggcacg cagccgcggc acgtgccgac gctgcgtact gccgttctcc gggtcggcga
    16741 tgcggaaact gacgatgccg agctggggat cggcctcgaa cgcggaacga accgtttcgg
    16801 ccgtagtttt gtccggaagc cgaccatcgt cgtccagaaa cagtagtacg tcgacctcgc
    16861 tgccccccgg gccgaacgcc tcgatgccca cgttccgccc gccggggatg ccgagattct
    16921 gcggcagctc cagggtgcgc acaccgggcg gcagatcggg cagctcggca ccgttgccga
    16981 cgaccaccac ctcgatggcc gcgccgtcct gcgcggccac cgagtccagc agcgcccgca
    17041 gttcctccgg gcggtcgccc atcgtcagga tgaccgcacc cagtctgagc tgcgccgtac
    17101 ccaccacact cacctcagcc tgctcgacgc cagtacggac accaggtgca gcagagtctg
    17161 caccagcgcg acggcggcca gcagggccac gccgaggcgg gtgaagaaca gatcgccccg
    17221 gaccaggtcg agcaccgcca ccagcaggat cagcagcgat gcctcgacgc cgccgaccag
    17281 ccggtggaac ttcagcgccg cggcggccct gcgggccagc gcgagaccgg acgaccgggg
    17341 tatggccgcg tcgtcccgga ccgcgggcag gcccccgcgg gtcctggcga cgtcgaccag
    17401 gtccgtctcc gccttgatga ggatggcgcc gagcgcggcg agcgtaccga ggaacgccca
    17461 cagccagttc ggcgcggcct cctccacggc gaacacgtcg gcggcgcgca ggccgaagcc
    17521 gaccagcagg gcggcctcgg ccaggtagtg gccgacgcgg tccaggtaga cgccggtgat
    17581 ggaggtctgg ccgcgccagc gcgcgacttc gccgtccacg cagtcgagca ggaggtacag
    17641 ctggatgagc agcgcgccgg tcagcgcccc ggccggaccg gggacgagca gcgccgctcc
    17701 ggcggcgacg ccggtgagaa ccatcaggta cgtgagctgg ttcggcgaga tccgcgtgtt
    17761 caccaggtgc ctggtccagc gcagcgagat ctcgcgcatg tacaggcgcc cggcccagtg
    17821 ctcaccgctg cgccggtcct tcacccccga ggggtgcacg accggccgga gttcagctac
    17881 cgatggtttt gacatagtcc gcgtacgcgt ccctgatctg gtcggtggtc aggtcgagat
    17941 gttcgagaat ggtgtaacgg ccgggcctgg tctgcggggc gaaggccacc gccgccacga
    18001 actcgtcggc ggtgaagccg atgtggtcgg gcagcacggg cagcccgtgg cgccgcagca
    18061 cctcggcgat cagcccgcac tggtcgggag cgccgcgcag gtgcatggcg aacgcggcac
    18121 cgaggcccac ctgctcgccg tgcagcgcgg agcgccgcgg gtggagcagg tccagggcgt
    18181 gggagatctc gtggcaggcg ccggaggagg gccgggtgtg gccggcgatc gacatggcga
    18241 tgccggagag gaccagcgcc tcggacagca cggtgaggaa cgggtcctcc ccgcagccgc
    18301 cggggtgccg cagcaccgcc tcgcccgcct gcctggccat ggccgcggcg agaccgtcga
    18361 tctgctcccc ggtctcgcgg tgggacagct cccagtcggc gatggccgaa atgttcgaca
    18421 cggcgtcgcc gatacccgac cgcacgtagc ggaccggtgc ctcgcggatc acgtccaggt
    18481 cgatgaccag cgcgatcggg gtggggacgc cgtaggagcc gcggcccgcg tcgttgtcca
    18541 gcgtggacac cggggagcag atgccgtcgt gcgagagatt ggtggcgacc gcgaccatcg
    18601 gcagcccgac gcgggcggcg gcgtacttgg cggcgtcgat gatcttgccc ccgcccaggc
    18661 cgaccacggc gtcgtagtgg cccgagcgca tggcatcggc cagctgcacg gcggcgtcga
    18721 tggtgccacc ggcgacctcg taccagtcgg cgcccggcag ggccgggctc agacgctcgc
    18781 gcagggccgc gccggagccg ttgctgatgg ccacggcgag ccggccggag gaggagatcc
    18841 gctggtcggc caggagcccc gccagattgt ccagggcccc ggcggtgatg tcgaccgaga
    18901 cgggggacgg gatgaggcgg gtcagtaccg gcacgcgatc tcccgtcccc gcgcaagatc
    18961 gtcgtggttg tcgatctcga cccagctgat gtccccgatg ggggcggtgt cgaggtggaa
    19021 cccgcggtgg accagctcct ggtagccgtc ctcgtagtag agctgcggat cacgctcgaa
    19081 cgtggtgcgc agcgcgtcgg ccagcgcgtc ggccgccgcg ggctcgatga gggtgacgcc
    19141 gatgtactcg ccggtggcct cggcgggctc catcagcttg gtgatgcgct gcacgccctt
    19201 ctcggggtcg gtgacgacct tcatctcctc gtcggccagc ttcttcaccg tgtccagggc
    19261 gaggatgatg cggccgccgt ccctgccacc ggcggcctgg gcggcgagca gcgtgcgctc
    19321 gacggagggc gggtgaacgg tgtcgccgtt ggcgaggatg accccctcct tgatgacatc
    19381 gcgcgcgcac cacagggagt acgcgttgtt ccactcctcg gccttgtcgt tctcgacgag
    19441 ggtcaggcgc accccgtggc ggcgctccag ggtctccttg cgctcgtaca cggcttcctt
    19501 gcggtagccg acgacgacgg cggcctcggt gaggccgacc tccgcgaagt tggccagagt
    19561 gaggtcgagg accgttctgc tgttctcgcc gtccgcctcg acgaccggca ccagcgcctt
    19621 gggcagggtg tcggtgtagg ggcgaagacg ccgtccggcg ccggcggcca gcacgaggcc
    19681 gatcatgcgg gttctccttc gtcgtgtacg gccggtgcct gggaggagac ccagaagcgg
    19741 atgctctcgc ccagcaccag gagcgccgtg gccccgccaa ggaccgcaag cgcggtggtg
    19801 aagccctgac cgtccgccca cagggcggcg gctgcgcagg ccaccaggac gcgcccctcg
    19861 tgaccgccgg tggccaggac cagccggcgg gggggcgccc cggcgccgcc ccggaggcgg
    19921 tacaccgtgt cgtagtgatg gtaggcgcaa gccgccacca caaagaaagc cgccggcaac
    19981 gctccgttta ccccggagtc ggccgcgagc accaggaagg tcaggtattc gccgcaccgg
    20041 aacagcgggg gaagcagcca gtcgaacggt ctgaccggct ccgcggcgac cgcgcggccg
    20101 gcgcacagcg cgtagagccc ggccgcggcg agggccgtcc agctgcccgc gacgccgggg
    20161 aggagcagca ggccgagcag cagcgccgtg ccggtcaggg cccacagcgg ggcggtacgg
    20221 ctgctgcccg cggccctggg gcgcagccgg gcgatgccct ccgcgagcgg gccgctgtcg
    20281 gcgaggccgg tgagcgcggc ggccgtgccc ggggcgccgc cgggcaggcg gcgggagcgc
    20341 agcagtcgcc cggcggtggt gtagcagccg gcgaggccgc cggcgatcag cagcacggtg
    20401 aaggtgacgc ggggggtggt cagcgcggtg aggacggcga tcagtgccca gcgttcgccg
    20461 atgggcagca cgatcatgcg gcgtacccac acggtccagc cgatgcggtc gagccggccg
    20521 gacagcgcgg tcgcgccgcc cgaggtaccg ccgggggcgg gcgggtgggc ctcgttgaac
    20581 gcgaagtcga cgatgtggcg gcaggtctgg aggatcatcg cgccgagcgc cagggcccat
    20641 acgtcgtccc cgccgcgggc ggcgccgagg gcgagtccgg cgtagtaggc gtactccttg
    20701 gcccggtcga aggtggcgtc cagccaggcc cccagcgtgg agtactgaag ggagtagcgg
    20761 gccagttggc cgtcggcgca gtcgaggacg aacgacgcga ggagcaggag cccggcggcg
    20821 acgaacccgc cgcgggtgcc ggtggccgcg cagccggccg cgacgagcgc ggtgatcagc
    20881 gaggcggtcg tgacctggtt gggcgtgagg ccgcggcggg cgcaccagcg ggccaggtag
    20941 cgggagtagg ggctgatgca gtgggtggtg aagaagccgt ccctcgactt cacggcggaa
    21001 cgcagccgca ccgcctcctc gtcgacggcg gcgacggcgg cctcggcccg cgcccgctcc
    21061 gcctccgagg cggggacggc ggcgacgagg gtacccagct ccggacggtg cacacgcgtt
    21121 cccgccgcgt cgaggccggt ggccaggcgg tcggcgaggc agccggccgc cggcggcgcg
    21181 gccacggtgc ggcccgcggc ctccggcgcg cgccccgctc cctgggcggt gacggcggtc
    21241 agcgcgccgg ccaacgcacc gcgctcgcgc gggagtacgg tcacggcgcc cggcacggcg
    21301 gccgcgtcga acctggggtc ggtcagaccg aggcgcaggc tgtgccggtg gccgacgaag
    21361 cgcgggtcga cgaccgcgac gcgctcggcg gcggggaccg cgtcgagcgc ccgcgtcaac
    21421 ccggccgtgc cgtccgccac tcgaacggag aaacccagct cgcgcaggtc gtgttcgacc
    21481 ggcgacccgg gtgggggcgg accggtgagg atggcggtcg acagctgact cactccttgg
    21541 ggcagaaccg tccctgcggc tgcacgtcgg cagagattat ccgatgacca ccacacggca
    21601 agaatggcgt tgacatcagg aaaccccgag ttcatgtccg gcggccgaag cggcggtcga
    21661 tgcgactcta tgcgatgggc cggacacaca gcgcaagggg cgggtgccgc gcagcggtta
    21721 ggctgccgac atgagctggc tgatcaccgg cggcgccgga tacatagggg cgcacgtcgt
    21781 cgagagcatg tgtgcggcgg gcgagcgggt ggtggtgctc gacgacctgt cctccggatc
    21841 gcccgccagg ctgcccgcgg acgtgccgct ggtgcgcggc tcggtgctcg accgggagct
    21901 gctggacgcg acgctggccg ggcacggggt caccggggtg gtgcacctgg ccgcgaggaa
    21961 gcaggtggcc gagtcggtgg ccgagccgac cggctactgg cgggccaacg tgcacggcct
    22021 gacggttctg ctcgaagcgg tcgcggcggc cggcctgcgc acgttcgtct tctcctcctc
    22081 ggcggccgtc tacggcatgc cgggcggcgg cctggtcacg gaggagacgc cgtgccaccc
    22141 gctgagcccg tacggcgaga cgaagctggc cggcgagtgg ctggtgcggg cggcgggccg
    22201 ggcgcacggc atcgccacgg cctgcctgcg ctatttcaac gtggcgggcg ccgcacgccc
    22261 cgagctggcg gacaccgggg cggccaacgt catcccgatg ttcttcgagc ggctggcgcg
    22321 cgggcaggcg ccggagatct tcggcgacga ctacccgacg ccggacggca gctgcgtgcg
    22381 cgactacgtg cacgtggccg atctggcgga ggcgcacctg gcggccgccc gccacctctc
    22441 gggccgcccg gcggccgggg gcgaggacct cacggtgaac atcggcaccg ggcgcggggc
    22501 ctcggtgaag gagctggcgg cgctggtcgg acaggtcacc ggccacggcg gcccgccgcg
    22561 gatctcgggg cgcaggccgg gcgatccggc ccgggtcgtg gcctcggtcg acctggccgc
    22621 ggaacggctg ggcttcacgg ccgggcgagg tctggaggag atggtctcct cggcctgggc
    22681 gggctggtgt catctgcacc cacagatgta gctcctccac catcgccgca cgtcaggcga
    22741 ccgggccgca ctccggatga acgcgcaggt cagagcacat gacaacggtg ttcagtgccg
    22801 cgttgccgaa gggccaggac ccgtagttca ctgtggggtg ccgacgaaaa aagggggcgt
    22861 gcgatgggag ccggacacca ccacggagga gcgccgcccg ccgggcccgg cacggcgggg
    22921 gcggcctacc gggggcgcct gcgggtggcc ctggccatcg cctgcgtgct gctggtggcg
    22981 gagctggccg gggccgcggc aacgggctcg ctcgcgctgc tcgcggatgc cggtcacgtg
    23041 gcgacggacg ccgtgggcat cggcatggcg ctgctggcca tccacgttgc caaccggccc
    23101 gcgggcagcg accggcgcac tttcggcttc gcccgcgcgg agatcctggc cgcgctggcc
    23161 aactgcgtgc tcctgctggg cgtcggcggc tacatcctgg tcgaggcgat cggccggctg
    23221 cgcgacccgg ccgaggtccc cggcgggctg accgtggtct tcggtgtcgt cggcctgctc
    23281 ctcaactgcg cctcgctggc gctgctgatg cgcgggcagc gcgaaagcct gaacgtgcgc
    23341 ggcgcgttcc tcgaagtggc cgcggatgcc ctgggttcgc tcgcggtggt ggcggcggcg
    23401 ctggtgatcg tgttcaccgg ctggcagcag gccgacccgg tcgcctcgtt gctgatcgcg
    23461 ctgctgatcg tgccgcgcac ggtgaagctg gcccgggagg cgctggacgt gctgctcgaa
    23521 tccgcgccga aggacgtgcg ggtcgcggag gtcagggcgc acatactgga gttgcccggc
    23581 gtggaggacc tgcacgacct gcacgtgtgg acgatcacct cggggatgcc cgcgctgtcc
    23641 gcgcacgtcg tcgtcgcgcg ggagacgctg gacgcggtgg ggcacgaacg gctgctgcac
    23701 gacctccagg gctgcctggg cgagcacttc gacgtggcgc actgcacgtt ccagctggag
    23761 ccctcggggc atgcggcaca cgaagtgggc ctctgccact gatccggtgc ggcacactgg
    23821 tccgagcccg cgcatgcggg acgcagggac gaagcgcggg gaaggtggac atgccgcaca
    23881 gcaccgacgc cacggcggag ccggtcatgc tggaactggt cgatgaggac ggccggacgg
    23941 tgggtaccgc ggagaagctg tccgcgcacc gggctcccgg gcggctgcac cgggccttct
    24001 cggtcttcct gttcgacgcc ggggggcggc tgctgctcca gcgccgcgcg ccggggaagt
    24061 accactcccc cggcgtctgg tcgaacacgt gctgcggaca tccctacccg ggggagccgc
    24121 cgttcctggc cgccacccgg cgcaccgtcg aagagctggg cgcggcgccc gagtcgctgc
    24181 gggcggcggg caccgtccgc tacaaccacc ccgaccccgc ctccggcctc gtcgagcagg
    24241 agtacaacca cctgttcgcc ggggtggtga gcatgccgct gcggcccgat cccgaggaga
    24301 tcgcggacac cgcgt
//
